No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditions
|
313291 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
243 |
4. Check minimum number of eventsNone |
243 |
5. Include endpointsNone |
243 |
6. Filter based on genotype QC (FinnGen only) |
220 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- D07
- Name in latin
- Carcinoma in situ prostatae
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of vagina
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of other and unspecified genital organs
- In situ neoplasms
- Any operation in hilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 220 | 220 | - |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | - |
| Median age at first event (years) | 58.46 | 58.46 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 226
- Matched controls
- 2260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
380.4
311.7
147
11
LEB00
NOMESCO Finland
Biopsy of vagina
228.1
307.7
169
29
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
+∞
276.6
205
*
ULA02
NOMESCO Finland
Kolposcopy
108.1
218.7
207
207
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
1083.0
153.1
133
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
32.8
151.4
180
241
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
28.9
148.5
169
210
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
20.3
119.3
125
130
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
28.7
99.1
73
37
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
20.6
94.9
84
63
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
33.1
89.2
61
25
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
270.3
88.3
85
5
LDA10
NOMESCO Finland
Curettage of cervix uteri
13.4
64.9
72
76
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
27.2
63.9
46
21
N87.0
ICD-10 Finland
Mild cervical dysplasia
16.7
51.8
47
35
N89.0
ICD-10 Finland
Mild vaginal dysplasia
70.8
44.6
50
9
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
14.5
42.2
41
34
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
212.9
35.9
36
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
9.3
30.4
40
51
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
127.4
22.0
23
*
D06BB10
ATC
imiquimod; topical
6.5
20.7
37
66
LEB10
NOMESCO Finland
Excision of lesion of vagina
44.4
19.9
24
6
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
+∞
19.0
18
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
36.3
18.4
23
7
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
3.4
17.9
136
698
D07.2
ICD-10 Finland
Carcinoma in situ: Vagina
+∞
15.8
15
*
N90.0
ICD-10 Finland
Mild vulvar dysplasia
85.8
14.8
16
*
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
27.7
13.6
18
7
N87.1
ICD-10 Finland
Moderate cervical dysplasia
10.3
13.4
26
28
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
18.7
12.8
19
11
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.2
12.1
59
225
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
11.6
11
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.5
10.0
38
123
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
38.4
9.1
11
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.7
9.0
175
1270
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
9.0
41
149
ZXC10
NOMESCO Finland
Use of laser
7.5
8.8
20
29
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
6.9
99
608
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
6.5
37
151
L04AX01
ATC
azathioprine; systemic
4.3
6.5
17
42
LFC00
NOMESCO Finland
Partial excision of vulva
71.8
6.5
7
*
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
18.7
6.3
9
5
8070/2-C52.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vagina, NOS
+∞
6.3
6
*
J01EA01
ATC
trimethoprim; systemic
2.1
6.1
86
519
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
6.1
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
16
38.83
76.66
4.8
1.6
—
—
—
0
0
97
128
12.52
75.62
4.4
1.5
—
—
—
0
0
180
583
11.26
61.59
4.6
1.5
—
—
—
0
0
153
962
2.83
12.14
3.4
2.7
—
—
estimate
—
0
0
55
259
2.48
7.30
1.7
1.9
—
—
—
0
0
57
277
2.41
7.05
1.8
2.0
—
—
—
0
0
36
140
2.87
6.95
1.6
1.8
—
—
—
0
0
38
170
2.48
5.55
1.9
1.8
—
—
—
0
0
39
180
2.41
5.32
6.2
5.1
252.88
248.80
u/l
0.06
34
169
78
478
1.96
5.19
2.5
2.2
—
—
—
0
0
52
289
2.04
4.49
1.8
1.7
1120.13
1180.16
nmol/l
0.20
42
219
133
1004
1.79
4.35
3.1
2.5
83.83
79.60
nmol/l
0.83
119
917
53
301
1.99
4.30
2.6
1.9
—
—
—
0
0
186
1573
2.03
4.06
6.5
4.6
14.52
10.97
mm/h
2.29
172
1469
145
1148
1.73
3.78
7.0
4.4
6.14
6.39
mmol/l
1.10
138
1076
7
9
7.98
3.58
1.4
1.7
—
—
—
0
0
127
980
1.68
3.55
11.1
6.4
1.22
1.22
mmol/l
0.56
104
853
113
851
1.66
3.43
2.3
2.0
98.16
99.91
pmol/l
0.17
60
435
31
158
2.11
3.34
5.7
3.0
118.88
69.73
ng/l
1.91
26
139
40
225
1.95
3.31
6.9
5.0
—
—
—
0
0
73
495
1.70
3.28
3.3
2.6
295.42
304.10
umol/l
0.37
65
445
10
25
4.14
3.12
1.5
1.4
—
—
—
0
0
42
249
1.84
2.96
4.6
4.6
32.29
33.93
%
0.52
28
165
113
876
1.58
2.89
10.0
5.7
1.22
1.22
mmol/l
0.22
98
813
71
493
1.64
2.87
3.4
2.2
2.78
2.91
mg/l
0.16
65
427
21
98
2.26
2.81
9.0
6.6
24.41
25.18
mmol/l
0.39
21
98
109
845
1.56
2.75
7.9
4.3
35.99
36.55
g/l
0.57
99
804
25
127
2.09
2.73
16.7
5.7
10.55
8.20
mmol/l
1.34
25
121
144
1191
1.58
2.71
14.9
10.2
3.78
3.90
e9/l
0.29
130
1040
15
61
2.56
2.68
1.1
1.3
—
—
—
0
0
31
172
1.93
2.67
2.7
3.0
—
—
—
0
0
18
81
2.33
2.62
2.1
1.9
—
—
—
0
0
98
750
1.54
2.57
4.5
3.2
2.38
2.37
mmol/l
0.28
81
692
10
31
3.33
2.55
1.0
1.1
—
—
—
0
0
76
553
1.56
2.48
1.9
1.6
21.53
21.88
nmol/l
0.06
61
474
83
617
1.55
2.46
5.4
3.5
0.00
0.00
estimate
0.50
26
215
17
78
2.28
2.38
1.9
1.8
—
—
—
0
0
31
181
1.83
2.30
8.5
7.9
0.45
1.39
mmol/l
0.86
26
156
18
86
2.19
2.30
1.3
1.3
4.83
2.19
u/ml
—
7
12
18
86
2.19
2.30
1.4
1.3
2.89
15.99
u/ml
—
7
21
24
129
1.96
2.27
2.4
1.4
—
—
—
0
0
177
1565
1.60
2.24
13.2
8.0
74.14
77.11
u/l
0.62
166
1483
132
1100
1.48
2.19
3.7
3.1
110.66
78.13
ug/l
1.35
123
1036
34
208
1.75
2.17
2.8
1.9
—
—
—
0
0
7
19
3.77
2.17
1.4
1.5
—
—
—
0
0
7
19
3.77
2.17
1.4
1.5
—
—
—
0
0
7
19
3.77
2.17
1.4
1.5
—
—
—
0
0
88
685
1.47
2.03
5.9
2.9
—
—
—
0
0
91
713
1.46
2.03
4.1
3.4
20.79
115.16
ng/l
0.52
51
441
7
21
3.41
1.98
1.9
1.8
—
—
—
0
0
5
11
4.62
1.95
3.6
2.8
0.60
0.91
index
—
5
11
81
626
1.46
1.92
4.7
3.8
17.35
6.82
mg/mmol
0.40
37
336
12
52
2.38
1.91
4.1
4.1
25.48
25.10
mmol/l
0.28
12
52
7
22
3.25
1.89
1.9
1.7
—
—
—
0
0
82
642
1.44
1.79
5.8
2.3
70.65
66.27
u/l
0.10
77
604
12
54
2.29
1.77
4.7
2.9
2.21
1.31
mg/l
1.24
12
49
5
13
3.91
1.72
1.0
1.0
2249.80
2024.00
miu/ml
—
5
13
5
13
3.91
1.72
1.4
1.2
0.44
0.78
e9/l
—
5
13
210
1974
1.90
1.71
19.1
12.9
82.78
84.85
ml/min/173m2
0.72
196
1823
10
42
2.44
1.64
1.5
1.1
—
—
—
0
0
13
63
2.13
1.63
1.5
1.2
—
—
—
0
0
131
1126
1.39
1.63
5.6
3.6
0.00
0.00
estimate
0.50
28
224
65
496
1.44
1.62
1.5
1.6
—
—
—
0
0
64
487
1.44
1.61
4.1
3.1
1869.72
734.50
ng/l
0.83
51
408
11
50
2.26
1.59
3.5
2.5
—
—
—
0
0
23
138
1.74
1.59
1.4
1.4
—
—
—
0
0
20
116
1.79
1.54
3.3
2.4
1.94
3.64
ug/l
1.91
14
103
11
51
2.22
1.53
1.2
1.5
—
—
—
0
0
30
196
1.61
1.53
2.8
1.9
—
—
—
0
0
17
94
1.87
1.52
1.7
2.1
1819.39
4462.78
u/l
—
8
38
132
1144
1.37
1.52
5.7
3.6
0.00
0.04
estimate
1.08
28
218
131
1135
1.37
1.50
5.5
3.6
0.00
7.19
estimate
0.50
28
226
10
45
2.28
1.48
1.4
2.1
—
—
—
0
0
19
110
1.79
1.48
6.3
1.9
24.87
5.82
iu/ml
—
7
25
5
16
3.17
1.44
1.0
1.1
—
—
—
0
0
5
16
3.17
1.44
1.0
1.4
—
—
—
0
0
6
22
2.77
1.44
1.3
1.0
—
—
—
0
0
6
22
2.77
1.44
1.2
1.1
—
—
—
0
0
16
89
1.86
1.41
1.5
1.4
—
—
—
0
0
5
17
2.98
1.36
3.6
2.5
23.80
13.55
index
—
5
11
8
34
2.40
1.30
1.9
1.5
—
—
—
0
0
8
35
2.33
1.28
2.1
1.2
—
—
—
0
0
8
35
2.33
1.28
2.1
1.2
—
—
—
0
0
11
56
2.01
1.24
1.8
1.1
—
—
—
0
0
16
95
1.74
1.17
2.0
1.6
—
—
—
0
0
7
31
2.30
1.11
2.6
1.2
—
—
—
0
0
7
31
2.30
1.11
2.6
1.2
—
—
—
0
0
7
31
2.30
1.11
2.6
1.2
—
—
—
0
0
7
31
2.30
1.11
2.6
1.2
—
—
—
0
0
7
31
2.30
1.11
2.6
1.2
—
—
—
0
0
7
31
2.30
1.11
2.6
1.2
—
—
—
0
0
65
530
1.32
1.05
5.3
2.8
0.21
0.38
e6/l
1.00
49
369
9
47
1.95
1.03
1.6
1.4
—
—
—
0
0
204
1951
1.47
0.92
4.4
4.1
1.30
1.24
mmol/l
0.67
182
1835
33
248
1.39
0.90
2.2
1.6
1.31
1.32
%
0.03
26
218
20
136
1.52
0.90
4.2
2.4
65.95
67.59
g/l
0.22
15
128
100
878
1.25
0.88
5.5
3.3
0.00
0.03
estimate
0.96
24
186
22
154
1.47
0.87
1.4
1.4
—
—
—
0
0
6
32
1.90
0.82
1.0
1.3
—
—
—
0
0
212
2050
1.55
0.82
5.3
4.9
1.57
1.59
mmol/l
0.34
190
1940
15
98
1.57
0.80
1.4
1.4
137.86
187.69
miu/ml
—
7
46
0
25
0.00
0.79
0.0
1.0
—
96.50
—
0
20
9
55
1.66
0.74
2.1
1.5
—
—
—
0
0
34
266
1.33
0.74
2.3
1.8
30.20
29.01
s
0.69
34
259
59
497
1.25
0.74
2.0
1.7
1.06
1.01
mg/l
0.04
48
398
5
26
1.94
0.71
1.2
1.4
—
—
—
0
0
5
27
1.87
0.69
1.4
1.8
—
—
—
0
0
39
315
1.29
0.68
5.3
2.6
1.22
0.91
e6/l
0.18
22
148
210
2036
1.44
0.68
24.3
13.5
18.08
19.44
mg/l
0.34
174
1616
212
2060
1.47
0.66
5.3
5.0
4.86
4.89
mmol/l
0.16
193
1957
11
71
1.58
0.63
2.1
1.2
—
—
—
0
0
47
396
1.24
0.59
3.2
2.3
2.45
2.45
mmol/l
0.02
38
356
6
36
1.68
0.57
1.7
1.5
—
—
—
0
0
6
37
1.64
0.56
1.2
1.4
—
—
—
0
0
47
399
1.22
0.55
2.0
1.7
480.38
14620330.24
pmol/l
0.50
42
342
6
99
0.60
0.53
1.3
1.7
—
—
—
0
0
73
652
1.18
0.51
4.4
2.9
0.00
0.02
estimate
0.74
24
183
7
47
1.50
0.48
1.1
1.1
—
24.12
—
0
17
197
1912
1.24
0.45
6.9
5.9
37.55
38.42
mmol/mol
0.96
179
1810
5
31
1.63
0.43
1.2
2.2
—
—
—
0
0
205
2001
1.26
0.42
5.5
4.8
5.73
5.75
mmol/l
0.07
187
1881
5
33
1.53
0.41
1.4
1.3
—
—
—
0
0
8
60
1.35
0.40
2.0
2.6
25.45
25.37
mmol/l
—
8
60
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
5
35
1.44
0.39
2.6
1.9
14.82
16.96
%
—
5
35
5
35
1.44
0.39
1.0
2.0
13.40
13.29
%
—
5
35
9
70
1.30
0.37
1.1
1.1
—
5.63
—
0
12
5
80
0.62
0.36
3.4
3.0
11.58
1667.13
u/ml
—
5
71
6
42
1.44
0.36
1.8
1.6
—
—
—
0
0
211
2074
1.26
0.32
6.0
5.6
2.84
2.86
mmol/l
0.11
192
1962
54
494
1.12
0.27
1.4
1.3
1.71
10.48
u/ml
3.06
23
197
24
207
1.18
0.26
1.5
1.8
3.52
3.44
mmol/l
0.11
16
157
32
284
1.15
0.25
6.1
2.7
4.81
3.92
e6/l
0.19
16
116
64
595
1.11
0.24
1.4
1.3
0.57
1.49
u/ml
1.45
19
183
19
162
1.19
0.23
1.3
1.4
—
26.36
—
0
10
5
38
1.32
0.23
1.8
1.7
—
—
—
0
0
54
499
1.11
0.23
5.6
3.5
1.02
1.02
kg/l
0.44
39
324
5
41
1.22
0.22
4.8
3.8
61.20
58.75
u/ml
—
5
41
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
23.81
—
0
10
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
12
0.00
0.21
0.0
1.0
—
135.33
—
0
12
0
12
0.00
0.21
0.0
1.0
—
96.33
—
0
6
0
12
0.00
0.21
0.0
1.2
—
9.26
—
0
12
0
12
0.00
0.21
0.0
1.0
—
109.00
—
0
6
0
13
0.00
0.21
0.0
1.0
—
47.06
—
0
13
150
1463
1.08
0.17
4.4
3.1
60.64
36.77
u/l
0.68
140
1400
8
68
1.18
0.17
1.5
1.1
—
—
—
0
0
8
69
1.17
0.16
1.5
1.1
—
—
—
0
0
9
78
1.16
0.15
1.7
1.8
—
—
—
0
0
9
78
1.16
0.15
1.2
1.3
—
—
—
0
0
12
102
1.19
0.15
7.4
2.2
0.60
0.60
%
0.01
12
102
94
964
0.96
0.09
2.0
1.9
1.37
1.35
mmol/l
0.11
67
817
20
185
1.09
0.08
2.2
2.7
59.00
70.23
ml/min/173m2
—
5
84
19
205
0.92
0.08
5.1
4.1
2.09
8.81
ug/l
2.12
13
159
7
85
0.82
0.07
1.0
1.1
1.50
1.65
g/l
—
7
85
9
88
1.02
0.07
1.7
1.1
0.91
0.90
g/l
—
9
88
28
267
1.06
0.05
1.8
2.0
3.11
3.23
ratio
0.26
19
220
54
527
1.03
0.04
1.3
1.4
16.83
29.57
iu/ml
1.49
16
182
11
103
1.07
0.02
8.0
2.3
0.92
1.14
%
0.61
11
103
143
1422
1.02
0.01
3.6
3.4
—
—
—
0
0
16
154
1.04
0.00
5.6
2.2
0.27
0.87
e6/l
0.46
16
144
20
194
1.03
0.00
5.1
2.2
36.13
29.33
u/l
0.36
15
159
13
128
1.02
0.00
1.1
1.1
—
—
—
0
0
14
138
1.02
0.00
1.3
1.4
—
—
—
0
0
198
1984
0.98
0.00
6.4
6.0
1.72
1.81
mu/l
0.44
179
1877
175
1754
0.99
0.00
5.4
5.0
14.36
14.50
pmol/l
0.40
154
1636
20
203
0.98
0.00
1.4
1.3
87.84
168.32
u/ml
—
7
92
34
335
1.02
0.00
3.8
3.7
141.05
124.94
ng/l
0.04
22
224
10
95
1.06
0.00
6.5
3.2
40.88
46.92
%
—
10
95
0
6
0.00
0.00
0.0
2.3
—
45.53
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
113.83
—
0
6
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
6.12
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_VAGINA – Carcinoma in situ of vagina
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).