Carcinoma in situ of other and unspecified genital organs

CD2_INSITU_GENITAL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D07
  • Cause of death: ICD-10 D07

2 out of 7 registries used, show all original rules.

365

4. Check minimum number of events

None

365

5. Include endpoints

823

6. Filter based on genotype QC (FinnGen only)

742

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D00-D09
Name in latin
Carcinoma in situ organorum genitalium aliorum sive non specificatorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 742 742 -
Unadjusted period prevalence (%) 0.26 0.26 -
Median age at first event (years) 60.27 60.27 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
771
Matched controls
7710
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
40.5
307.7
326
137
ULA02
NOMESCO Finland
Kolposcopy
25.6
307.7
524
591
LEB00
NOMESCO Finland
Biopsy of vagina
43.3
307.7
247
83
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
95.1
303.0
159
21
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
54.3
275.4
160
37
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
11.7
270.3
437
777
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
646.1
245.1
230
5
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
3099.5
226.6
208
*
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
+∞
226.6
206
*
D07.0
ICD-10 Finland
Carcinoma in situ: Endometrium
+∞
188.5
173
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
9.7
172.0
245
354
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
8.1
170.0
307
581
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
147.8
137
*
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
432.3
144.0
140
*
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
46.0
126.1
75
18
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
43.6
124.4
75
19
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
15.2
122.9
114
87
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
236.4
119.4
120
6
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
17.6
116.6
99
64
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
9.4
111.0
146
186
N90.0
ICD-10 Finland
Mild vulvar dysplasia
60.1
108.6
61
11
N89.0
ICD-10 Finland
Mild vaginal dysplasia
35.4
102.1
65
20
D06BB10
ATC
imiquimod; topical
8.1
101.3
153
229
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
9.5
94.9
122
150
LFC00
NOMESCO Finland
Partial excision of vulva
180.2
92.4
95
6
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
14.2
85.7
81
63
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
113.0
84.0
90
9
LDA10
NOMESCO Finland
Curettage of cervix uteri
7.0
81.0
137
230
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
14.4
75.1
70
53
N87.0
ICD-10 Finland
Mild cervical dysplasia
9.5
72.8
91
107
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
5.5
65.8
146
316
A63.0
ICD-10 Finland
Anogenital (venereal) warts
8.3
64.5
90
121
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
9.2
58.4
74
88
N76.6
ICD-10 Finland
Ulceration of vulva
16.2
49.8
43
28
B01AB10
ATC
tinzaparin; parenteral
3.8
49.7
182
575
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
5.0
40.3
93
205
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.6
37.4
397
2227
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.1
36.4
184
701
D07AD01
ATC
clobetasol; topical
2.8
34.4
225
985
N85.1
ICD-10 Finland
Endometrial adenomatous hyperplasia
9.0
34.3
43
50
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
9.5
31.5
38
42
N87.1
ICD-10 Finland
Moderate cervical dysplasia
6.2
29.0
51
87
8070/2-C51.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vulva, NOS
+∞
27.2
26
*
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
145.1
26.8
28
*
ZXC96
NOMESCO Finland
Robot assisted procedure
7.2
25.2
38
55
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
129.0
23.7
25
*
ZXC10
NOMESCO Finland
Use of laser
5.8
22.0
41
74
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
21.2
130
539
N95.0
ICD-10 Finland
Postmenopausal bleeding
2.6
21.1
149
662
128
Kela drug reimbursment
Cancers of female genital organs
5.0
21.1
46
96
LCA06
NOMESCO Finland
Biopsy of endometrium
2.3
20.3
184
914
LEB10
NOMESCO Finland
Excision of lesion of vagina
16.6
20.3
32
20
D07.2
ICD-10 Finland
Carcinoma in situ: Vagina
+∞
19.9
19
*
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
6.6
19.8
32
50
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
8.0
19.7
27
35
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
3.8
19.2
60
166
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.2
18.9
52
131
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
184.1
17.6
18
*
N90.4
ICD-10 Finland
Leukoplakia of vulva
13.0
17.2
30
24
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.2
17.2
73
246
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.3
16.9
44
106
D06BB04
ATC
podophyllotoxin; topical
3.5
16.8
61
187
D07.3
ICD-10 Finland
Carcinoma in situ: Other and unspecified female genital organs
+∞
16.7
16
*
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
6.3
16.5
28
46
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
15.6
334
2237
ULC02
NOMESCO Finland
Hysteroscopy
2.8
15.5
82
313
B01AB05
ATC
enoxaparin; parenteral
1.9
15.2
287
1845
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
46.0
15.1
18
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.4
14.7
106
472
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.9
14.4
573
4611
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
43.3
14.1
17
*
SPAT1312
SPAT
General health counselling
1.9
14.0
269
1727
J02AC01
ATC
fluconazole; systemic
1.8
14.0
429
3172
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
12.3
13.7
24
20
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
4.0
13.4
38
98
P01AB01
ATC
metronidazole; oral, rectal
1.7
12.9
389
2838
2333B
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Other and unspecified female genital organs[CARCINOMA IN SITU VULVAE]
+∞
11.5
11
*
8077/2-C51.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of labium minus
+∞
11.5
11
*
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
15.3
11.3
18
12
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
15.3
11.3
18
12
SPAT1263
SPAT
Sampling
1.7
11.3
340
2451
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
3.6
11.3
37
106
J01EA01
ATC
trimethoprim; systemic
1.7
11.1
270
1834
C51.81
ICD-10 Finland
Squamous cell carcinoma of the vulva
44.0
10.9
13
*
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
2.5
10.8
72
308
8542/3-C51.9
ICD-O-3
Paget disease, extramammary of vulva, NOS
111.5
10.4
11
*
G01AA10
ATC
clindamycin; vaginal
1.8
10.4
178
1090
N84.0
ICD-10 Finland
Polyp of corpus uteri
2.1
10.2
105
539
E0000UV, ,
ATC
1.6
10.1
362
2705
8380/2-C54.1
ICD-O-3
Endometrioid intraepithelial neoplasia of endometrium
11.5
10.1
18
16
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
20.3
9.8
14
7
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
3.8
9.8
30
82
8380/3-C54.9
ICD-O-3
Endometrioid adenocarcinoma, NOS, of corpus uteri
10.2
9.6
18
18
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
15.3
9.5
15
10
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.8
9.5
29
79
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
9.4
108
577
L43.8
ICD-10 Finland
Other lichen planus
3.8
9.4
28
75
L04AA06
ATC
mycophenolic acid; systemic
4.6
9.4
22
49
JN4AD
NOMESCO Finland
Body CT examination
2.1
9.2
95
488
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
9.2
255
1777
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
9.0
37
123
N02BE01
ATC
paracetamol; systemic, rectal
2.4
8.9
718
6559
C03CA01
ATC
furosemide; systemic
1.7
8.7
212
1424
SPAT1310
SPAT
Counselling related to known health issue
1.6
8.7
251
1762
UJF32
NOMESCO Finland
Coloscopy
1.7
8.5
213
1441
D07AC01
ATC
betamethasone; topical
1.6
8.5
294
2154
LFC96
NOMESCO Finland
Other partial excision of vulva or perineum
+∞
8.3
8
*
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
8.3
109
611
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
8.3
358
2756
XX3DW
NOMESCO Finland
Time consuming IT work
2.0
8.2
97
523
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
8.2
67
314
L04AA01
ATC
[U] ciclosporin
4.8
8.1
18
38
A02BC02
ATC
pantoprazole; systemic
1.6
8.0
553
4717
127
Kela drug reimbursment
Transplant complication
6.7
7.9
19
29
WZA90
NOMESCO Finland
Other medical or dental certificate
1.7
7.9
195
1311
SPAT1153
SPAT
Removal of sutures
1.6
7.8
246
1757
C54.10
ICD-10 Finland
Malignant tumor of endometrium without histology
15.2
7.7
12
8
8070/3-C52.9
ICD-O-3
Squamous cell carcinoma, NOS, of vagina, NOS
45.4
7.7
9
*
LFD10
NOMESCO Finland
Vulvectomy and excision of regional lymph nodes
45.4
7.7
9
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
7.5
7.7
17
23
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
3.6
7.5
24
68
JN4BD
NOMESCO Finland
Extensive body CT
2.0
7.4
78
404
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
7.4
79
412
8077/2-C51.8
ICD-O-3
Squamous intraepithelial neoplasia, high grade of overlapping lesion of vulva
+∞
7.3
7
*
ZZR00
NOMESCO Finland
Flap of skin
3.9
7.3
21
55
A12AA04
ATC
calcium carbonate; oral
7.4
7.2
16
22
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.6
7.2
17
38
YX9VG
NOMESCO Finland
Other MRI eamination with high intensity magnet for dose design of radiotherapy
20.2
7.1
10
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
7.1
326
2515
E000001, ,
ATC
1.7
7.1
164
1081
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
7.0
233
1675
R50.9
ICD-10 Finland
Fever, unspecified
1.8
7.0
115
690
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
2.3
6.8
52
237
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.2
6.8
26
83
C52.91
ICD-10 Finland
Squamous cell carcinoma of the vagina
40.4
6.8
8
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
6.7
178
1214
WF090
NOMESCO Finland
Profylactic radiotherapy
22.7
6.7
9
*
C51.9
ICD-10 Finland
Malignant neoplasm: Vulva, unspecified
22.7
6.7
9
*
LFE10
NOMESCO Finland
Plastic repair of vulva
12.4
6.6
11
9
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
6.6
75
400
H02AB06
ATC
prednisolone; systemic
1.5
6.5
371
2976
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.4
6.5
18
34
LCD11
NOMESCO Finland
Laparoscopically assisted vaginal hysterectomy
3.5
6.5
22
65
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
6.4
187
1302
8070/2-C52.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vagina, NOS
+∞
6.3
6
*
N99.8
ICD-10 Finland
Other postprocedural disorders of genitourinary system
+∞
6.3
6
*
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.3
276
2100
LEC00
NOMESCO Finland
Partial excision of vagina
26.9
6.2
8
*
SPAT1301
SPAT
No procedures
1.5
6.2
232
1704
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
5.4
6.2
17
32
WX402
NOMESCO Finland
General anaesthesia
1.6
6.2
177
1227
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
6.2
177
1227
LWA00
NOMESCO Finland
Repair of wound dehiscence in gynaecological surgery
12.6
6.1
10
8
D39.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other female genital organs
12.6
6.1
10
8
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
6.0
104
632
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
6.0
113
703

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
202
151
17.77
224.50
4.1
1.8
—
—
—
0
0
557
3150
3.77
61.99
4.6
2.1
—
—
—
0
0
207
652
3.97
57.43
1.7
1.4
—
—
—
0
0
537
3347
2.99
43.23
3.1
2.6
—
—
estimate
—
0
0
35
21
17.41
42.09
1.9
1.8
2.97
1.94
ug/l
—
25
8
102
278
4.08
33.64
1.3
1.5
120.86
272.03
pmol/l
1.23
102
273
360
2309
2.05
20.70
2.5
2.2
—
—
—
0
0
339
2134
2.05
20.46
5.4
4.2
0.00
0.00
estimate
0.80
96
759
450
3224
1.95
17.88
5.5
4.3
36.32
36.06
g/l
0.54
425
3024
284
1748
1.99
17.64
2.4
2.2
—
—
—
0
0
154
779
2.22
15.95
2.2
1.6
—
—
—
0
0
430
3120
1.86
15.53
4.7
3.6
6.47
6.26
ph
3.33
251
1745
511
3925
1.90
15.29
5.4
4.1
0.00
0.02
estimate
1.49
104
778
181
993
2.08
15.15
1.4
1.3
—
—
—
0
0
588
4765
1.99
14.54
6.3
4.9
20623.70
3119.93
e6/l
—
7
75
500
3849
1.85
14.45
5.3
4.1
0.00
0.00
estimate
0.50
102
785
500
3893
1.81
13.43
5.4
4.1
18.06
2.00
estimate
0.42
104
810
105
491
2.32
12.98
2.7
2.3
2.81
6.18
ug/l
4.75
94
434
396
2907
1.74
12.79
5.1
4.0
0.04
0.08
estimate
0.40
85
640
134
716
2.05
11.82
5.6
6.9
0.60
1.20
mmol/l
1.10
106
597
256
1698
1.76
11.54
5.8
4.2
1.02
1.90
kg/l
0.50
173
1138
507
4055
1.73
11.45
5.6
4.5
6.55
6.54
mmol/l
0.05
487
3827
115
597
2.09
10.92
5.9
7.6
121.02
118.34
g/l
0.81
115
585
132
721
2.00
10.91
5.8
7.0
7.40
7.42
ph
1.38
90
405
349
2551
1.67
10.85
3.7
3.1
—
—
—
0
0
163
972
1.86
10.33
2.3
1.9
—
—
—
0
0
285
2016
1.66
9.80
3.6
3.0
1341.56
920.31
ng/l
0.48
247
1708
393
3040
1.60
9.21
19.9
12.5
1.23
1.17
inr
1.15
339
2500
510
4212
1.62
8.97
12.1
9.2
3.98
3.96
e9/l
0.08
466
3680
226
1546
1.65
8.66
3.4
2.6
8.64
7.64
e6/l
0.23
210
1419
266
1917
1.59
8.16
1.4
1.5
—
—
—
0
0
73
359
2.14
7.94
1.4
1.2
—
—
—
0
0
468
3849
1.55
7.85
7.1
5.9
9.39
10.38
umol/l
1.81
446
3658
415
3340
1.53
7.57
6.7
5.6
1.21
1.22
mmol/l
3.28
375
3064
306
2317
1.53
7.37
3.7
2.4
60.07
62.48
u/l
0.17
285
2125
175
1163
1.65
7.37
3.5
2.9
0.80
0.82
mmol/l
0.75
164
1090
626
5554
1.68
7.20
10.4
7.8
79.21
77.80
u/l
0.34
599
5254
452
3736
1.51
7.05
7.5
6.3
1.21
1.22
mmol/l
3.46
384
3212
311
2390
1.50
6.86
4.2
3.2
6.68
6.64
mmol/l
0.07
260
2013
567
4942
1.56
6.70
5.0
3.9
—
0.22
—
0
9
237
1726
1.54
6.70
5.0
3.9
—
—
—
0
0
117
729
1.71
6.22
2.6
2.1
0.00
0.04
estimate
0.78
14
138
563
4936
1.52
6.13
6.2
4.8
—
3.01
—
0
5
292
2263
1.47
5.97
4.0
3.3
46.20
27.60
mg/l
0.79
183
1311
294
2300
1.45
5.65
4.6
4.0
8.66
6.12
mg/mmol
0.38
173
1290
283
2225
1.43
5.19
4.3
3.2
21.25
48.32
e6/l
1.86
242
1677
50
252
2.05
5.15
2.1
2.1
1397.21
4223.11
u/l
1.22
20
102
129
864
1.59
5.15
7.8
4.1
1.05
1.03
mmol/l
0.34
118
777
438
3735
1.40
4.95
9.2
6.0
0.04
0.04
e9/l
0.50
395
3213
247
1908
1.43
4.94
4.2
3.1
0.26
0.42
e6/l
1.41
201
1373
741
7061
2.27
4.86
18.7
13.4
—
—
—
0
0
284
2258
1.41
4.81
2.6
2.1
125.03
146.75
u/l
0.98
273
2145
444
3809
1.39
4.76
9.3
6.0
1.78
1.93
e9/l
2.69
412
3364
698
6531
1.73
4.75
4.6
4.2
1.32
1.25
mmol/l
2.24
637
5997
435
3728
1.38
4.64
9.2
6.0
0.54
0.55
e9/l
0.30
394
3214
62
353
1.82
4.50
2.9
2.0
0.00
0.01
estimate
0.50
12
106
84
523
1.68
4.48
10.2
5.6
8.98
8.56
mmol/l
0.27
79
497
320
2623
1.38
4.43
4.8
3.9
56.29
85.03
e6/l
0.95
248
1774
737
7034
2.08
4.38
24.0
16.9
139.58
139.72
mmol/l
0.76
730
6892
221
1707
1.41
4.34
5.9
4.7
—
—
—
0
0
333
2757
1.37
4.29
3.9
3.4
2.37
2.37
mmol/l
0.70
297
2512
737
7040
2.06
4.27
24.1
17.0
3.95
3.93
mmol/l
0.79
729
6885
145
1041
1.48
4.19
1.8
1.6
—
—
—
0
0
445
3863
1.36
4.19
9.5
6.3
0.18
0.18
e9/l
0.09
413
3376
83
527
1.64
4.11
2.3
2.9
76.47
74.54
e9/l
0.16
68
386
15
47
3.23
4.07
1.9
1.6
33.52
44.97
%
2.11
15
47
221
1725
1.39
4.05
2.6
2.5
313.55
313.47
umol/l
0.00
198
1521
314
2605
1.35
3.89
4.6
3.6
49.15
67.95
ng/l
0.25
217
1735
750
7233
2.36
3.87
16.0
12.1
23.98
23.81
u/l
0.12
737
7025
721
6864
1.78
3.85
22.9
14.9
21.66
20.90
mg/l
0.25
617
5610
108
750
1.51
3.66
1.7
1.4
—
—
—
0
0
278
2292
1.33
3.51
4.7
3.7
7.40
7.40
ph
0.16
211
1621
36
187
1.97
3.49
1.3
1.2
—
—
—
0
0
102
707
1.51
3.49
2.8
2.7
1.96
1.90
%
0.26
89
632
24
112
2.18
3.09
1.4
1.3
—
—
—
0
0
22
99
2.26
3.08
2.8
3.2
1.66
1.66
%
0.00
22
91
93
653
1.48
3.00
5.0
4.3
0.70
0.99
%
0.70
37
172
8
17
4.74
2.92
1.0
1.2
—
—
—
0
0
25
122
2.08
2.90
3.5
2.3
38.18
58.12
ug/min
0.29
13
71
165
1294
1.35
2.85
3.7
2.8
458.08
487.44
mosm/kgh2o
1.17
149
1137
44
262
1.72
2.83
1.8
2.1
1.54
1.57
g/l
0.05
35
227
103
747
1.44
2.82
2.8
2.1
378.18
378.80
nmol/l
0.01
97
697
122
913
1.40
2.81
1.5
1.4
—
—
—
0
0
689
6566
1.46
2.73
7.3
6.1
38.90
38.86
mmol/mol
0.04
648
6152
724
6979
1.61
2.63
6.5
5.9
2.75
2.80
mmol/l
0.72
670
6505
99
724
1.42
2.60
3.9
3.9
7.30
7.36
ph
1.13
64
503
43
261
1.69
2.60
1.2
1.3
9.18
2.08
u/ml
—
10
27
11
36
3.08
2.57
2.4
2.6
0.82
0.81
index
0.02
11
36
211
1742
1.29
2.51
1.8
1.7
0.91
1.00
mg/l
0.26
170
1340
57
376
1.56
2.48
4.3
3.4
7.43
7.42
ph
0.47
46
320
716
6896
1.54
2.47
5.7
5.1
4.75
4.83
mmol/l
1.62
667
6447
228
1905
1.28
2.46
2.9
2.3
3.30
2.90
mg/l
1.26
201
1634
284
2439
1.26
2.44
3.7
3.3
—
0.78
—
0
9
702
6737
1.47
2.43
6.1
5.1
5.92
5.83
mmol/l
1.15
647
6216
9
27
3.36
2.40
1.2
1.1
7.44
7.40
ph
—
9
19
37
221
1.71
2.39
1.3
1.2
—
—
—
0
0
75
531
1.46
2.35
8.5
6.9
—
—
—
0
0
147
1165
1.32
2.35
3.7
2.8
2.42
1.20
e6/l
0.72
97
579
11
39
2.85
2.35
1.0
1.3
—
—
—
0
0
23
119
1.96
2.32
1.5
1.3
—
—
—
0
0
634
5996
1.32
2.31
5.9
5.1
14.78
14.72
pmol/l
0.24
591
5556
264
2260
1.26
2.31
8.0
6.0
—
—
—
0
0
42
263
1.63
2.28
1.2
1.3
6.65
8.77
u/ml
0.15
11
46
7
18
3.91
2.25
1.7
1.4
—
—
—
0
0
152
1218
1.31
2.25
1.7
1.7
1336.91
1212.95
nmol/l
0.86
122
914
25
135
1.88
2.24
7.2
3.2
—
—
—
0
0
86
631
1.41
2.24
4.2
2.7
1.90
2.19
mmol/l
0.33
77
545
138
1092
1.32
2.23
3.2
2.3
2.33
2.39
g/l
0.49
127
1006
406
3657
1.23
2.20
3.5
3.1
110.38
89.46
ug/l
1.50
379
3427
21
108
1.97
2.17
1.4
1.2
324.31
269.46
u/ml
0.38
16
67
85
626
1.40
2.17
5.4
4.4
0.07
0.09
%
0.18
29
144
14
61
2.32
2.15
3.7
3.0
56.29
54.00
%
0.20
14
56
56
381
1.51
2.15
4.5
2.7
24.47
24.58
mmol/l
0.10
56
373
7
19
3.71
2.15
1.0
1.0
—
—
—
0
0
711
6862
1.46
2.15
5.5
5.0
1.54
1.59
mmol/l
2.51
656
6381
191
1587
1.27
2.13
3.2
2.6
2.47
2.45
mmol/l
0.97
168
1446
26
145
1.82
2.13
2.9
1.6
—
—
—
0
0
85
629
1.39
2.11
5.2
4.2
0.29
0.76
%
2.32
28
161
122
957
1.33
2.10
3.8
3.2
8.45
4.59
e9/l
0.69
102
833
70
501
1.44
2.10
1.4
1.3
—
—
—
0
0
146
1179
1.29
2.04
2.2
1.8
—
—
—
0
0
22
119
1.87
1.99
1.1
1.1
—
—
—
0
0
247
2130
1.23
1.98
1.8
1.6
20.98
21.49
nmol/l
0.18
215
1793
7
21
3.35
1.97
1.4
1.6
14.29
7.10
%
—
7
21
14
64
2.21
1.95
2.1
1.2
31.44
34.64
g/l
0.45
14
59
54
374
1.48
1.93
4.0
1.8
25.27
7.39
iu/ml
1.04
14
88
85
641
1.37
1.90
5.8
4.6
0.07
0.14
%
0.41
28
132
107
836
1.33
1.90
1.5
1.7
—
—
—
0
0
86
651
1.36
1.88
4.1
2.7
7.39
7.38
ph
0.11
55
360
756
7420
1.97
1.88
33.8
23.2
269.00
263.14
e9/l
1.67
751
7290
22
122
1.83
1.86
10.2
3.7
2.91
2.95
mmol/l
0.02
16
88
756
7422
1.96
1.85
33.8
23.2
4.36
4.40
e12/l
1.46
750
7269
756
7422
1.96
1.85
33.8
23.2
6.68
6.58
e9/l
0.89
750
7263
5
12
4.19
1.82
3.8
5.0
—
—
—
0
0
7
23
3.06
1.80
1.4
1.6
30.43
27.48
%
—
7
23
40
264
1.54
1.80
4.4
3.6
—
—
—
0
0
11
47
2.36
1.78
1.4
1.4
5.87
5.57
ug/l
0.08
11
38
363
3280
1.20
1.77
2.2
2.1
97.27
99.01
pmol/l
0.29
195
1609
6
18
3.35
1.75
1.0
3.2
59.67
49.89
%
—
6
18
192
1633
1.23
1.73
1.8
1.5
2.17
2.24
g/l
0.23
123
973
142
1170
1.26
1.69
3.2
2.3
11.64
12.79
umol/l
0.87
131
1084
384
3500
1.19
1.67
9.8
6.1
27.80
28.71
%
0.94
368
3307
30
189
1.61
1.65
3.1
2.9
2.05
2.29
index
0.11
20
91
31
198
1.59
1.62
18.9
8.9
—
—
—
0
0
695
6733
1.33
1.56
7.0
6.2
1.90
1.87
mu/l
0.12
653
6297
11
51
2.17
1.51
1.2
1.1
—
—
—
0
0
12
58
2.09
1.49
2.6
3.4
—
—
—
0
0
12
58
2.09
1.49
1.3
1.3
—
—
—
0
0
374
3428
1.18
1.46
10.2
6.2
8.46
8.51
%
0.14
355
3200
122
1006
1.25
1.46
3.5
2.3
21.11
21.57
%
0.11
112
937
41
287
1.45
1.44
2.6
4.9
1.70
1.51
%
0.87
41
275
6
22
2.74
1.43
3.3
2.2
0.59
0.62
mmol/l
—
6
22
350
3196
1.17
1.42
15.1
10.8
0.00
0.00
e9/l
0.39
305
2616
101
817
1.27
1.42
3.5
2.2
6.88
6.25
umol/l
0.18
91
710
9
40
2.26
1.40
1.0
1.1
2068.22
1686.25
miu/ml
—
9
40
10
46
2.19
1.40
1.5
1.6
14.70
25.76
ug/l
—
10
46
10
46
2.19
1.40
1.7
1.2
—
—
—
0
0
28
182
1.56
1.39
1.6
2.4
—
—
—
0
0
18
104
1.75
1.38
5.8
1.4
—
—
—
0
0
48
350
1.40
1.36
2.3
2.0
—
—
—
0
0
32
216
1.50
1.35
3.8
1.3
—
—
—
0
0
30
200
1.52
1.34
3.9
1.3
—
—
—
0
0
503
4748
1.17
1.30
4.0
3.2
51.61
41.89
u/l
0.86
473
4454
124
1039
1.23
1.29
2.4
2.2
162.08
110.29
ug/g
0.35
92
812
371
3422
1.16
1.29
10.0
6.1
2.83
2.77
%
0.23
354
3188
10
48
2.10
1.28
1.9
1.5
—
—
—
0
0
32
219
1.48
1.28
3.8
1.3
—
—
—
0
0
26
170
1.55
1.27
4.3
1.3
—
—
—
0
0
373
3445
1.16
1.27
9.6
6.0
58.09
56.84
%
1.24
361
3272
107
885
1.24
1.26
1.5
1.3
—
—
—
0
0
20
123
1.64
1.25
3.4
7.7
11.65
10.86
mmol/l
0.51
20
112
20
123
1.64
1.25
3.4
7.7
105.85
105.32
mmol/l
0.19
20
112
14
78
1.81
1.21
1.8
1.5
—
—
—
0
0
14
78
1.81
1.21
1.8
1.5
—
—
—
0
0
14
78
1.81
1.21
1.8
1.5
—
—
—
0
0
14
78
1.81
1.21
1.8
1.5
—
—
—
0
0
25
164
1.54
1.21
2.9
1.9
122.47
127.93
g/l
0.47
15
129
21
132
1.61
1.21
1.1
1.2
—
—
—
0
0
13
71
1.85
1.20
2.1
1.4
—
—
—
0
0
395
3676
1.15
1.19
2.7
2.5
82.31
79.71
nmol/l
0.99
358
3338
8
38
2.12
1.18
1.4
2.1
7.39
7.95
mmol/l
—
8
38
12
64
1.89
1.18
1.2
1.3
—
—
—
0
0
22
141
1.58
1.18
5.5
3.5
3.36
4.28
e9/l
2.20
22
141
8
40
2.01
1.12
4.8
3.4
626.13
1177.92
u/ml
—
8
40
15
88
1.72
1.12
4.5
3.0
—
—
—
0
0
368
3419
1.15
1.11
10.3
6.2
0.66
0.71
%
0.93
349
3176
72
578
1.27
1.11
1.5
1.3
321.39
127.67
u/ml
0.49
63
539
31
218
1.44
1.11
4.0
1.3
—
—
—
0
0
131
1123
1.20
1.10
1.1
1.2
—
—
—
0
0
38
278
1.39
1.10
3.0
2.6
25.19
25.54
mmol/l
0.30
38
271
35
253
1.40
1.08
1.7
1.7
19.80
20.35
s
0.38
30
222
35
253
1.40
1.08
1.3
1.4
0.31
0.29
mg/l
0.08
16
95
61
482
1.29
1.07
1.8
1.8
—
—
—
0
0
77
627
1.25
1.06
4.2
3.1
98.01
76.28
ng/l
1.49
68
550
93
775
1.23
1.04
1.5
1.4
—
—
—
0
0
72
583
1.26
1.04
4.9
4.0
—
—
—
0
0
11
60
1.85
1.03
2.1
1.2
—
—
—
0
0
266
2430
1.14
1.01
9.8
5.9
—
—
—
0
0
40
300
1.35
1.01
1.5
1.6
5.38
11.68
u/ml
—
8
62
5
23
2.18
0.98
1.0
1.4
—
—
—
0
0
60
480
1.27
0.97
2.4
2.9
191.55
183.30
ng/l
0.05
53
448
28
199
1.42
0.97
1.4
1.7
—
—
—
0
0
7
37
1.90
0.94
1.3
1.7
1.14
1.25
nmol/l
—
7
28
21
303
0.68
0.93
1.0
1.1
—
—
—
0
0
21
302
0.69
0.92
1.3
1.6
1724.61
992.22
mu/l
1.25
15
252
6
28
2.15
0.91
4.0
4.0
—
—
—
0
0
6
28
2.15
0.91
1.3
2.1
15.98
16.31
%
—
6
28
30
219
1.38
0.90
3.8
1.3
—
—
—
0
0
268
2469
1.13
0.88
4.0
2.9
28.93
28.57
u/l
0.09
252
2335
21
144
1.47
0.88
1.4
1.3
59.50
60.83
mmol/l
0.05
16
119
12
72
1.68
0.85
1.3
1.1
—
—
—
0
0
19
129
1.48
0.84
3.9
2.3
15.73
15.93
%
0.13
19
129
66
546
1.23
0.82
3.4
3.7
4.57
4.53
pmol/l
0.08
56
482
50
401
1.26
0.82
1.5
1.2
—
—
—
0
0
14
89
1.58
0.81
1.2
1.2
—
—
—
0
0
24
173
1.40
0.79
5.2
3.5
55.81
58.93
%
0.59
24
173
6
33
1.82
0.79
4.0
3.5
—
—
—
0
0
8
48
1.67
0.79
1.3
1.2
—
—
—
0
0
8
48
1.67
0.79
1.5
1.3
—
—
—
0
0
34
261
1.32
0.77
1.4
1.3
215.39
231.39
miu/ml
0.11
18
122
65
542
1.22
0.76
2.8
2.5
21.81
22.99
au/ml
—
10
46
10
59
1.70
0.76
1.5
1.5
35704.80
148196.27
e6/l
—
5
37
14
91
1.55
0.75
1.0
1.3
—
—
—
0
0
13
83
1.58
0.75
2.2
1.8
18.31
22.97
ng/l
0.77
13
83
13
83
1.58
0.75
1.5
1.7
60.63
53.94
%
—
8
50
20
141
1.43
0.75
3.3
3.5
541.11
2325.90
u/ml
0.48
20
133
131
1164
1.15
0.75
1.5
1.4
720.00
596.80
titre
0.25
35
275
10
60
1.68
0.72
1.9
1.2
6.22
6.28
mmol/l
—
10
55
82
705
1.18
0.71
1.3
1.5
—
—
—
0
0
17
118
1.45
0.69
1.9
1.6
0.32
0.63
g/l
—
10
99
43
348
1.25
0.68
7.0
8.8
16.00
15.61
%
0.57
43
337
7
43
1.63
0.67
2.0
1.3
60.14
69.56
umol/l
—
7
43
10
62
1.62
0.65
1.0
1.2
—
—
—
0
0
10
154
0.64
0.64
2.2
4.7
—
—
—
0
0
20
146
1.38
0.64
1.2
1.1
—
—
—
0
0
20
146
1.38
0.64
1.2
1.1
—
—
—
0
0
17
121
1.41
0.62
1.1
1.2
—
—
—
0
0
68
583
1.18
0.62
1.2
1.3
—
—
—
0
0
8
50
1.61
0.61
1.0
1.2
—
—
—
0
0
26
201
1.30
0.59
1.3
1.2
—
—
—
0
0
36
291
1.25
0.59
1.4
1.7
—
16.34
—
0
7
16
115
1.40
0.57
1.0
1.1
1.56
1.85
eliau/ml
—
8
58
13
90
1.45
0.55
3.5
2.7
—
—
—
0
0
261
2764
0.92
0.54
3.1
3.2
—
—
—
0
0
16
216
0.74
0.54
3.9
4.1
14.87
31.25
u/ml
2.03
16
210
9
61
1.48
0.54
1.3
1.1
—
—
—
0
0
16
117
1.38
0.52
1.1
1.0
—
—
—
0
0
84
745
1.14
0.52
3.1
4.0
2.79
9.36
ug/l
4.36
70
598
6
40
1.50
0.51
1.3
1.9
—
—
—
0
0
6
40
1.50
0.51
1.0
1.3
—
—
—
0
0
224
2102
1.09
0.51
4.2
3.5
0.00
0.01
estimate
1.34
80
639
165
1526
1.10
0.51
1.7
1.7
461.71
32000447.85
pmol/l
1.81
136
1275
31
252
1.24
0.50
1.3
1.4
295.31
305.96
ug/g
0.07
16
144
36
300
1.21
0.47
1.3
1.3
—
—
—
0
0
10
68
1.48
0.47
1.8
9.9
7.66
7.12
mmol/l
—
10
55
7
49
1.43
0.46
1.0
1.0
—
—
—
0
0
166
1547
1.09
0.45
1.4
1.3
6.79
13.50
u/ml
0.98
70
596
17
130
1.31
0.44
1.2
1.3
—
0.46
—
0
7
47
406
1.17
0.43
3.3
2.4
117.94
128.56
g/l
2.97
47
395
21
262
0.80
0.43
4.3
2.9
21.41
831.85
u/ml
0.91
16
229
15
113
1.33
0.43
1.1
1.0
—
—
—
0
0
70
625
1.13
0.42
1.9
1.7
—
—
—
0
0
226
2141
1.08
0.41
3.5
3.1
0.50
0.00
—
8
43
0
15
0.00
0.41
0.0
2.7
—
—
—
0
0
8
59
1.36
0.41
1.0
1.1
—
—
—
0
0
23
186
1.24
0.40
3.1
4.0
1.58
4.11
ratio
0.73
14
111
5
34
1.47
0.40
1.8
1.5
144.80
145.24
nmol/l
—
5
34
29
242
1.21
0.39
2.6
2.9
147.73
384.34
mg/l
1.64
11
77
44
504
0.87
0.38
2.9
2.5
—
—
—
0
0
65
583
1.13
0.37
2.7
2.8
63.99
67.43
g/l
1.80
53
539
11
81
1.36
0.36
1.5
2.5
—
—
—
0
0
62
687
0.89
0.34
1.3
1.2
—
—
—
0
0
19
154
1.24
0.34
1.6
1.2
—
—
—
0
0
201
1913
1.07
0.33
1.4
1.3
0.63
1.51
u/ml
2.23
54
506
22
263
0.83
0.32
1.5
2.0
2.02
26.36
iu/l
—
7
106
10
74
1.36
0.32
1.9
2.1
88.68
89.70
%
—
10
74
12
92
1.31
0.32
1.0
1.1
—
—
—
0
0
18
147
1.23
0.31
2.3
1.9
—
—
—
0
0
33
378
0.87
0.30
2.3
2.4
—
—
—
0
0
63
573
1.11
0.30
1.4
1.8
3.49
3.49
mmol/l
0.01
39
413
13
102
1.28
0.30
1.2
1.0
—
—
—
0
0
14
112
1.25
0.28
1.2
1.3
0.21
0.35
nmol/l
—
9
81
22
258
0.85
0.27
1.1
1.2
1.64
1.64
g/l
0.02
22
258
5
71
0.70
0.26
1.8
2.1
1.18
1.20
mmol/l
—
5
71
9
76
1.19
0.24
2.0
2.1
—
—
—
0
0
12
96
1.25
0.24
1.1
1.6
—
—
—
0
0
11
88
1.25
0.22
1.3
1.6
—
—
—
0
0
110
1043
1.06
0.22
4.3
3.0
3.73
4.53
e6/l
0.43
59
453
57
616
0.92
0.22
1.4
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
1.57
—
0
12
0
12
0.00
0.21
0.0
1.8
—
5.67
—
0
12
0
13
0.00
0.21
0.0
3.2
—
—
—
0
0
6
48
1.25
0.20
1.2
1.6
9.57
11.53
umol/l
—
6
43
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
13
108
1.21
0.20
1.2
1.3
—
—
nmol/l
—
0
0
69
646
1.07
0.20
1.2
1.2
95.96
150.19
u/ml
1.09
27
268
64
601
1.07
0.17
5.6
3.5
1.23
1.23
mmol/l
0.17
53
511
20
176
1.14
0.17
1.1
1.5
21.60
603.04
e6/l
0.78
15
131
20
176
1.14
0.17
1.1
1.4
1.00
15.05
e6/l
1.37
15
126
5
66
0.76
0.17
1.0
1.1
—
—
—
0
0
171
1661
1.04
0.14
1.3
1.3
23.81
31.75
iu/ml
0.74
49
535
9
83
1.09
0.14
2.4
1.7
3.51
50.83
u/ml
—
9
83
23
208
1.11
0.14
1.2
1.3
407.39
511.13
mg/l
1.19
23
196
11
128
0.86
0.13
2.4
1.5
—
—
—
0
0
11
94
1.17
0.13
1.5
1.2
—
—
—
0
0
321
3164
1.02
0.11
2.0
1.9
1.42
1.33
mmol/l
1.20
266
2697
52
496
1.05
0.10
1.3
1.3
29.23
31.42
iu/l
0.17
43
438
135
1320
1.03
0.08
3.9
3.7
155.15
323.85
ng/l
0.78
93
958
6
72
0.83
0.07
1.7
2.1
104.33
105.92
mmol/l
—
6
72
6
72
0.83
0.07
1.0
1.1
—
—
—
0
0
6
72
0.83
0.07
1.7
2.1
3.90
3.94
mmol/l
—
6
72
6
75
0.80
0.07
1.0
1.1
125.00
110.49
pmol/l
—
6
75
15
137
1.10
0.07
2.7
3.9
17.49
20.42
mg/l
—
8
93
14
151
0.93
0.05
1.4
1.5
—
—
—
0
0
34
351
0.97
0.03
1.1
1.1
—
—
—
0
0
72
708
1.02
0.03
3.3
2.4
32.41
41.66
u/l
1.16
58
579
14
148
0.94
0.02
1.3
1.5
—
—
—
0
0
10
107
0.93
0.02
1.3
1.2
—
—
—
0
0
14
146
0.96
0.00
1.3
1.5
1.31
1.31
mm
—
8
108
61
616
0.99
0.00
3.0
2.5
6.05
6.09
ph
0.10
38
413
12
115
1.04
0.00
1.2
1.1
2.50
5.02
u/ml
—
6
43
16
165
0.97
0.00
1.3
1.5
—
—
—
0
0
19
185
1.03
0.00
1.4
1.6
56.55
57.75
ug/l
0.04
14
157
20
195
1.03
0.00
1.1
1.1
—
—
—
0
0
25
254
0.98
0.00
1.7
1.2
—
—
—
0
0
26
257
1.01
0.00
2.2
2.1
8.71
10.39
g/l
1.11
18
236
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
377.20
—
0
5
0
5
0.00
0.00
0.0
1.8
—
586.62
—
0
5
6
66
0.91
0.00
1.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
69
0.87
-0.00
2.7
2.8
—
—
—
0
0
8
82
0.98
-0.00
1.3
2.1
31.00
31.50
pg
—
8
82
0
9
0.00
-0.00
0.0
4.4
—
7.43
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
59.43
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.2
1.1
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
3.22
—
0
9
9
94
0.96
-0.00
3.6
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.8
1.7
5.96
6.93
mmol/l
—
5
35

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_GENITAL – Carcinoma in situ of other and unspecified genital organs

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).