Carcinoma in situ of penis

CD2_INSITU_PENIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only males

244368

2. Check conditions

  • not C3_PENIS
244216

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D07.4&
  • Hospital discharge: ICD-9 2335
  • Cause of death: ICD-10 D07.4&
  • Cause of death: ICD-9 2335
  • Cancer registry: Topography ICD-O-3 C60
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

74

4. Check minimum number of events

None

74

5. Include endpoints

None

74

6. Filter based on genotype QC (FinnGen only)

64

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D07
Name in latin
Carcinoma in situ vesicae urinariae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 64 - 64
Unadjusted period prevalence (%) 0.03 - 0.03
Median age at first event (years) 66.90 - 66.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
68
Matched controls
680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D07.4
ICD-10 Finland
Carcinoma in situ: Penis
+∞
72.3
56
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
11.8
20.2
26
34
KGB00
NOMESCO Finland
Biopsy of penis
86.6
13.1
14
*
N48.1
ICD-10 Finland
Balanoposthitis
21.7
12.5
18
11
KGD10
NOMESCO Finland
Destruction of lesion of penis
115.4
9.7
10
*
D04.8
ICD-10 Finland
Carcinoma in situ: Skin of other sites
+∞
9.6
9
*
D06BB10
ATC
imiquimod; topical
12.7
9.1
16
16
KGH10
NOMESCO Finland
Operation for phimosis
12.5
8.6
15
15
L43.8
ICD-10 Finland
Other lichen planus
+∞
8.5
8
*
E0000UV, ,
ATC
4.3
8.1
40
170
C60.1
ICD-10 Finland
Malignant neoplasm: Glans penis
89.4
7.6
8
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.9
7.5
20
53
A63.0
ICD-10 Finland
Anogenital (venereal) warts
34.0
7.3
9
*
Z2221
NOMESCO Finland
Medical doctor
4.0
7.1
29
106
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
19.2
7.0
10
6
WX320
NOMESCO Finland
Spinalanesthesy
3.8
6.5
29
112
8070/2-C60.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of penis, NOS
+∞
6.3
6
*
J02AC01
ATC
fluconazole; systemic
4.1
6.3
22
71

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
30
10.30
10.83
2.0
1.3
—
—
—
0
0
29
106
4.03
7.10
1.9
2.5
—
—
—
0
0
25
86
4.02
6.60
1.7
1.8
—
—
—
0
0
42
231
3.14
4.98
3.6
2.2
—
—
—
0
0
23
89
3.39
4.95
1.4
1.2
—
—
—
0
0
18
62
3.59
4.59
1.7
1.5
—
—
—
0
0
39
217
2.87
4.35
13.6
7.3
—
—
—
0
0
46
287
2.86
4.01
12.2
7.6
2.90
2.85
%
0.05
41
273
33
174
2.74
4.00
6.1
3.1
—
—
estimate
—
0
0
46
288
2.85
3.97
12.3
7.7
9.58
9.13
%
0.32
41
276
18
70
3.14
3.75
1.7
2.1
—
—
—
0
0
45
286
2.70
3.65
12.4
7.8
0.67
0.60
%
0.29
40
273
34
190
2.58
3.58
5.9
3.0
0.26
0.37
e6/l
0.27
27
135
11
29
4.32
3.37
1.4
2.0
—
—
—
0
0
30
164
2.48
3.24
2.7
2.0
3.47
2.70
mg/l
0.69
22
153
10
25
4.50
3.24
2.3
2.5
—
—
—
0
0
47
316
2.58
3.23
10.8
6.7
0.67
0.64
e9/l
0.20
38
274
47
317
2.56
3.19
10.8
6.7
0.04
0.04
e9/l
0.13
38
274
21
98
2.65
3.12
2.0
1.7
—
—
—
0
0
38
239
2.34
2.93
7.2
3.8
35.99
74.72
e6/l
0.46
29
174
6
9
7.18
2.93
4.0
1.4
—
—
—
0
0
47
326
2.43
2.87
11.7
7.2
0.21
0.21
e9/l
0.02
39
288
46
319
2.37
2.76
11.7
6.9
1.56
1.88
e9/l
0.83
40
283
22
113
2.40
2.64
4.8
2.8
0.69
0.38
e6/l
0.24
13
61
9
26
3.83
2.59
2.7
3.9
—
—
—
0
0
35
223
2.17
2.51
8.1
5.3
—
—
—
0
0
7
17
4.46
2.43
1.3
1.2
—
—
—
0
0
6
13
4.95
2.32
1.5
2.7
—
—
—
0
0
32
202
2.10
2.30
3.4
3.0
—
—
—
0
0
28
168
2.13
2.29
14.5
6.7
—
—
—
0
0
5
9
5.89
2.25
1.4
1.7
—
—
—
0
0
34
223
2.05
2.18
6.1
3.1
30.93
32.42
e6/l
0.02
29
169
43
308
2.08
2.16
17.7
11.1
1.20
1.19
mmol/l
0.19
37
275
39
271
2.03
2.11
3.7
3.6
—
—
estimate
—
0
0
9
33
2.98
2.02
10.9
28.6
16.07
14.89
%
—
9
33
38
266
1.97
1.97
2.9
2.1
100.84
91.13
pmol/l
0.53
23
151
29
188
1.95
1.86
11.8
4.2
7.39
7.39
ph
0.35
23
134
42
309
1.94
1.84
4.4
3.5
0.00
0.00
estimate
—
7
69
16
83
2.21
1.83
1.8
3.3
58.69
65.26
e9/l
0.45
11
64
38
272
1.90
1.79
19.4
14.7
0.00
0.01
e9/l
0.51
31
224
47
362
1.97
1.76
8.2
4.3
—
6.00
—
0
7
45
342
1.93
1.75
20.6
12.4
4.19
4.35
e9/l
0.12
39
301
5
13
4.06
1.74
1.0
2.1
—
—
—
0
0
13
63
2.31
1.73
2.6
1.4
—
—
—
0
0
13
63
2.31
1.73
7.6
9.5
1.22
1.39
mmol/l
0.37
13
63
8
31
2.79
1.72
3.9
2.7
1064.88
573.08
ug/l
—
8
31
7
25
3.00
1.70
1.7
1.4
—
—
—
0
0
11
50
2.43
1.67
5.5
8.3
23.03
24.81
mmol/l
0.67
11
50
35
248
1.85
1.67
3.9
3.0
6.00
6.09
ph
0.07
15
134
42
316
1.86
1.65
4.4
3.5
0.00
4.62
estimate
—
7
65
10
44
2.49
1.64
2.1
2.2
91.90
216.24
ng/l
—
10
38
42
317
1.85
1.62
4.5
3.4
0.00
0.00
estimate
—
7
71
15
80
2.12
1.60
8.3
17.4
7.42
7.42
ph
—
8
47
5
16
3.29
1.46
1.0
1.4
13.30
14.09
ug/l
—
5
16
0
41
0.00
1.36
0.0
1.4
—
—
—
0
0
22
144
1.78
1.30
3.1
2.8
—
—
—
0
0
20
128
1.80
1.27
3.7
3.9
25.60
318.31
ng/l
0.85
15
108
18
112
1.83
1.25
1.7
1.4
2.68
2.95
g/l
—
8
67
10
50
2.17
1.24
3.7
2.1
11.73
11.78
g/l
—
10
45
8
38
2.25
1.23
7.1
3.6
23.75
23.82
mmol/l
—
8
38
12
65
2.03
1.22
8.4
10.3
—
—
—
0
0
0
33
0.00
1.20
0.0
13.5
—
—
—
0
0
41
325
1.66
1.18
16.4
15.3
1.21
1.31
inr
0.62
28
274
7
34
2.18
1.06
1.0
1.1
—
—
—
0
0
11
62
1.92
1.01
3.1
5.0
0.80
1.00
%
—
5
29
12
70
1.87
1.00
9.7
19.4
119.92
123.73
g/l
0.32
12
70
30
227
1.58
1.00
2.3
2.1
1.44
1.42
mmol/l
0.02
25
187
14
210
0.58
0.99
3.9
3.5
—
—
—
0
0
25
187
1.53
0.85
2.0
1.7
20.28
18.87
nmol/l
0.17
20
149
52
455
1.61
0.85
6.1
5.4
3.08
3.02
ug/l
0.01
46
411
34
273
1.49
0.83
4.9
4.1
33.67
46.38
ng/l
0.45
26
213
5
27
1.92
0.70
1.0
1.0
—
—
—
0
0
7
43
1.70
0.69
7.1
3.1
—
—
—
0
0
8
49
1.72
0.65
1.5
2.1
—
0.00
estimate
—
0
12
6
35
1.78
0.59
1.2
2.2
—
0.00
estimate
—
0
11
6
38
1.63
0.56
9.8
4.5
—
—
—
0
0
9
63
1.49
0.55
7.9
4.5
0.76
1.84
mmol/l
—
9
49
6
39
1.59
0.54
9.0
2.2
1.23
1.24
%
—
6
39
60
560
1.61
0.51
41.6
20.0
37.36
26.85
mg/l
0.75
53
489
7
49
1.48
0.47
7.9
4.8
1.22
1.21
mmol/l
—
7
42
14
107
1.39
0.41
7.1
8.9
102.43
103.70
mmol/l
0.69
14
107
10
73
1.43
0.37
4.3
1.6
—
—
—
0
0
6
42
1.47
0.37
1.0
1.3
—
—
—
0
0
6
45
1.36
0.35
1.2
1.4
—
—
—
0
0
19
225
0.78
0.33
8.5
4.3
—
—
—
0
0
7
51
1.41
0.33
2.7
1.5
—
—
—
0
0
7
56
1.28
0.30
1.3
1.5
—
—
—
0
0
8
65
1.26
0.28
2.5
2.6
11.19
9.58
ug/l
—
8
56
56
534
1.28
0.25
6.1
4.7
1.48
1.34
mmol/l
0.34
50
495
5
38
1.34
0.24
7.4
2.1
0.58
0.64
%
—
5
38
53
505
1.22
0.22
6.2
4.1
1.73
2.03
mu/l
1.02
48
449
5
42
1.21
0.22
5.8
17.3
—
—
—
0
0
10
80
1.29
0.22
2.7
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
3.2
—
105.73
—
0
11
0
11
0.00
0.21
0.0
3.2
—
1.21
—
0
11
0
11
0.00
0.21
0.0
3.2
—
4.03
—
0
11
0
11
0.00
0.21
0.0
2.3
—
9.55
—
0
11
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
6
49
1.25
0.20
11.0
4.3
—
—
—
0
0
57
550
1.22
0.18
6.8
5.4
1.26
1.29
mmol/l
0.25
52
511
25
228
1.15
0.16
7.6
4.0
50.78
74.31
mg/l
0.33
18
169
17
152
1.16
0.14
1.4
1.3
—
—
—
0
0
10
87
1.18
0.10
1.6
1.3
—
—
—
0
0
19
175
1.12
0.10
4.1
3.3
0.00
0.42
estimate
—
6
59
58
567
1.16
0.09
29.1
18.6
—
—
—
0
0
25
236
1.09
0.08
9.0
4.6
12.46
11.54
mg/mmol
0.04
16
169
8
74
1.09
0.08
1.8
1.4
—
—
—
0
0
12
130
0.91
0.05
6.0
4.8
—
—
—
0
0
28
272
1.05
0.02
4.2
3.2
0.52
0.85
ug/l
1.53
22
184
24
237
1.02
0.00
4.7
3.5
0.00
0.00
estimate
—
6
60
19
194
0.97
0.00
5.4
3.4
0.00
0.00
estimate
—
6
65
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.4
—
2.36
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
64.75
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
19.0
—
1317.00
—
0
5
0
5
0.00
-0.00
0.0
11.4
—
739.00
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_PENIS – Carcinoma in situ of penis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).