pathological myopia: ['Excessive axial myopia associated with complications (especially posterior staphyloma and CHOROIDAL NEOVASCULARIZATION) that can lead to BLINDNESS.']
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
294 |
4. Check minimum number of eventsNone |
294 |
5. Include endpointsNone |
294 |
6. Filter based on genotype QC (FinnGen only) |
252 |
Control definitions (FinnGen only)
- Control exclude
- H7_VITREOUS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H44
- Name in latin
- Myopia degenerativa
Similar endpoints
↥List of similar endpoints to
Degenerative myopia
based on the number of shared cases.
Similar with more cases:
- Disorders of globe
- Disorders of vitreous body and globe
- Diseases of the eye and adnexa
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2133 | 1513 | 608 |
| Only index persons | 1912 | 1363 | 549 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.02 |
| Only index persons | 0.04 | 0.05 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 59.30 | 62.03 | 52.35 |
| Only index persons | 57.27 | 59.91 | 50.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 252 | 189 | 63 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.03 |
| Median age at first event (years) | 57.41 | 57.08 | 58.39 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 268
- Matched controls
- 2680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H44.2
ICD-10 Finland
Degenerative myopia
+∞
307.7
256
*
H52.1
ICD-10 Finland
Myopia
31.7
140.5
102
51
H26.4
ICD-10 Finland
After-cataract
9.7
65.9
98
151
CJB10
NOMESCO Finland
Laser discission of secondary cataract
9.9
60.6
84
118
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.3
56.1
117
257
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
16.1
50.6
46
34
H26.02
ICD-10 Finland
Presenil cataract
18.4
48.8
41
26
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.2
44.3
81
152
H33.0
ICD-10 Finland
Retinal detachment with retinal break
15.7
40.7
37
27
H43.8
ICD-10 Finland
Other disorders of vitreous body
12.8
33.3
34
30
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
6.0
33.3
70
148
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
7.4
29.8
48
77
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.5
29.3
98
304
S01ED51
ATC
timolol, combinations; ophthalmic
6.0
27.5
55
110
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
7.9
25.7
38
55
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.6
23.9
144
653
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.4
21.5
145
693
114
Kela drug reimbursment
Glaucoma
4.9
21.5
54
131
S01EC04
ATC
brinzolamide; ophthalmic
6.9
20.7
34
55
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
5.4
20.2
44
94
XCK00
NOMESCO Finland
Perimetry
5.8
19.5
39
77
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
6.2
18.2
33
59
S01EE01
ATC
latanoprost; ophthalmic
5.1
17.5
40
89
H33.3
ICD-10 Finland
Retinal breaks without detachment
6.7
17.2
29
48
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
6.0
17.1
32
59
3602A
ICD-9 Finland
Disorders of the globe, Degenerative disorders of globe[MYOPIA MALIGNA]
+∞
16.8
16
*
XCH00
NOMESCO Finland
Eye pressure measurement
6.2
16.7
30
53
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
22.7
16.3
23
11
CKC12
NOMESCO Finland
Photocoagulation of retina
7.0
15.7
25
39
H35.4
ICD-10 Finland
Peripheral retinal degeneration
48.0
15.3
18
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.8
15.1
113
548
H40.0
ICD-10 Finland
Glaucoma suspect
4.0
15.0
47
134
S01ED01
ATC
timolol; ophthalmic
6.7
14.5
24
39
Z3229
NOMESCO Finland
Other healthcare associate professional
4.1
14.4
43
118
XCK10
NOMESCO Finland
Photography of fundus of eye
3.7
12.6
44
135
ZXA10
NOMESCO Finland
Bilateral
2.7
11.4
76
340
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
26.3
11.3
15
6
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.4
11.2
155
971
H25.0
ICD-10 Finland
Senile incipient cataract
3.9
10.9
34
96
H53.0
ICD-10 Finland
Amblyopia ex anopsia
22.6
10.8
15
7
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
15.0
10.6
17
12
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
10.5
10
*
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
5.1
10.2
22
46
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
17.6
10.0
15
9
H26.2
ICD-10 Finland
Complicated cataract
17.6
10.0
15
9
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.8
9.9
56
228
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
9.4
9
*
H44.3
ICD-10 Finland
Other degenerative disorders of globe
+∞
9.4
9
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
51.7
8.7
10
*
S01EE04
ATC
travoprost; ophthalmic
8.7
8.7
18
22
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.8
8.7
49
199
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
4.4
8.6
22
53
CKD40
NOMESCO Finland
Endophotocoagulation of retina
20.8
8.5
12
6
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
20.8
8.5
12
6
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
92.9
8.5
9
*
CS494
NOMESCO Finland
Other visual field testing
8.0
8.3
18
24
S01EE03
ATC
bimatoprost; ophthalmic
8.2
8.0
17
22
H27.0
ICD-10 Finland
Aphakia
46.4
7.8
9
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
46.4
7.8
9
*
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
8.4
7.7
16
20
S01EA05
ATC
brimonidine; ophthalmic
7.5
7.6
17
24
CKC70
NOMESCO Finland
Circular buckling of sclera
82.3
7.5
8
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
+∞
7.3
7
*
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
7.3
7
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
30.9
7.2
9
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
7.3
7.1
16
23
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.6
7.1
17
39
S01EC03
ATC
dorzolamide; ophthalmic
14.3
6.9
11
8
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
41.1
6.8
8
*
XCD20
NOMESCO Finland
Photoangiography of eye
8.5
6.4
13
16
3745
FHL
Hard membrane girding, cerclage with coagulation
+∞
6.3
6
*
ZXA05
NOMESCO Finland
Left side
2.0
6.0
76
436
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
190
1.84
2.52
4.5
3.5
78.04
82.91
ng/l
0.23
24
164
43
277
1.66
2.24
1.5
1.9
—
—
—
0
0
18
89
2.10
2.11
1.4
1.6
—
—
—
0
0
205
1842
1.48
1.98
4.8
4.6
14.77
14.85
pmol/l
0.19
191
1670
32
483
0.62
1.80
1.5
1.3
13.50
31.54
iu/ml
—
8
166
130
1092
1.37
1.78
2.9
2.5
76.86
80.31
nmol/l
0.76
112
979
55
398
1.48
1.75
1.5
1.7
1344.40
1216.77
nmol/l
0.51
38
292
231
2144
1.56
1.74
6.3
6.3
38.79
39.09
mmol/mol
0.24
220
2001
6
20
3.04
1.59
1.5
1.2
—
—
—
0
0
38
262
1.52
1.52
1.6
2.0
—
—
—
0
0
50
367
1.45
1.48
1.8
2.0
—
—
—
0
0
5
16
3.16
1.44
1.2
1.6
108.40
69.94
umol/l
—
5
16
57
431
1.41
1.44
1.4
1.5
—
—
—
0
0
121
1039
1.30
1.31
2.1
2.1
95.81
97.54
pmol/l
0.13
56
516
126
1096
1.28
1.22
6.5
6.0
1.22
1.21
mmol/l
0.11
113
1003
32
443
0.68
1.20
1.5
1.3
18.33
12.19
u/ml
0.14
13
170
38
277
1.43
1.18
6.3
6.3
—
—
—
0
0
69
556
1.32
1.17
4.9
4.2
1.02
1.02
kg/l
0.25
46
364
62
495
1.33
1.12
1.8
1.8
482.13
18159651.29
pmol/l
0.50
47
402
11
60
1.87
1.04
3.7
4.3
3.55
3.89
mmol/l
1.43
11
60
5
107
0.46
1.03
2.0
2.9
81.00
1943.44
u/ml
—
5
94
137
1222
1.25
1.02
7.9
6.8
1.22
1.22
mmol/l
0.40
116
1041
0
29
0.00
0.98
0.0
1.7
—
—
—
0
0
10
54
1.88
0.98
1.6
1.0
167.40
15.41
e6/l
—
5
39
0
31
0.00
0.97
0.0
2.1
—
13.35
—
0
31
24
168
1.47
0.93
3.0
3.3
244.33
199.33
ng/l
0.22
24
152
242
2325
1.42
0.92
20.6
18.2
139.66
139.73
mmol/l
0.16
236
2273
232
2216
1.35
0.90
5.2
5.1
5.78
5.90
mmol/l
1.11
217
2024
27
196
1.42
0.88
1.6
2.6
70.21
64.42
ml/min/173m2
0.39
14
73
242
2330
1.40
0.85
20.8
18.2
3.95
3.96
mmol/l
0.15
236
2274
61
725
0.79
0.83
2.9
3.4
0.00
0.00
estimate
0.50
23
214
225
2148
1.30
0.81
6.0
5.7
1.85
1.89
mu/l
0.20
213
1951
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
21
149
1.44
0.78
7.1
8.9
0.54
0.64
%
0.61
21
149
235
2260
1.32
0.76
5.3
5.2
4.76
4.76
mmol/l
0.00
217
2079
85
741
1.22
0.75
2.8
3.1
809.96
1125.85
ng/l
1.07
74
619
234
2252
1.31
0.73
5.1
5.1
1.56
1.54
mmol/l
0.30
217
2061
9
56
1.63
0.73
2.0
1.1
—
—
—
0
0
21
152
1.41
0.71
7.1
8.7
1.21
1.30
%
0.20
21
152
12
77
1.58
0.70
1.5
1.3
—
—
—
0
0
13
87
1.52
0.64
1.4
1.7
4.04
4.20
ug/l
0.01
13
80
8
50
1.62
0.62
1.5
1.5
—
—
—
0
0
5
30
1.68
0.61
1.2
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
66
573
1.20
0.60
2.8
2.3
2.86
3.00
mg/l
0.18
60
489
49
413
1.23
0.60
3.1
2.8
1.67
1.02
e6/l
0.29
26
209
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
18
132
1.39
0.59
1.4
1.7
—
—
—
0
0
101
915
1.17
0.56
3.9
3.7
19.62
97.16
ng/l
0.66
75
640
59
512
1.20
0.54
2.7
2.6
2.46
2.45
mmol/l
0.02
49
460
245
2388
1.30
0.54
11.8
12.3
24.27
25.43
u/l
0.64
239
2307
246
2399
1.31
0.54
22.2
20.5
73.24
73.94
umol/l
0.17
241
2367
11
75
1.49
0.51
1.9
2.0
—
—
—
0
0
44
376
1.20
0.48
3.1
2.9
2.43
3.71
e6/l
0.52
22
171
21
164
1.30
0.48
1.5
1.9
3.47
3.53
mmol/l
0.09
15
127
236
2297
1.23
0.47
6.1
5.9
2.70
2.77
mmol/l
0.69
220
2113
7
48
1.47
0.47
1.4
2.8
7.04
8.44
pmol/l
—
7
48
76
684
1.16
0.46
3.3
3.1
0.66
0.43
e6/l
0.33
57
491
10
69
1.47
0.45
1.3
1.3
—
—
—
0
0
35
412
0.83
0.45
1.2
1.5
—
—
—
0
0
249
2441
1.28
0.43
26.3
24.1
252.28
253.06
e9/l
0.07
244
2395
249
2441
1.28
0.43
26.3
24.1
4.43
4.44
e12/l
0.11
244
2386
22
176
1.27
0.43
1.6
1.6
—
—
—
0
0
5
31
1.62
0.43
1.6
1.6
—
—
—
0
0
6
92
0.64
0.43
2.2
1.4
—
—
—
0
0
10
70
1.45
0.42
2.0
1.7
—
—
—
0
0
67
602
1.15
0.41
1.3
1.3
2.58
2.38
u/ml
0.03
15
186
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
2.5
—
82.71
—
0
15
0
15
0.00
0.41
0.0
3.7
—
1.47
—
0
15
0
15
0.00
0.41
0.0
2.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
83
760
1.13
0.39
2.2
2.4
58.44
61.75
u/l
0.20
77
701
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
145
1375
1.12
0.38
2.7
3.0
—
—
—
0
0
54
603
0.87
0.38
2.4
2.7
335.87
327.35
umol/l
0.29
48
527
29
341
0.83
0.37
3.7
2.4
18.18
22.66
%
1.87
24
311
6
43
1.40
0.35
1.5
1.3
—
—
—
0
0
6
43
1.40
0.35
1.5
1.3
—
—
—
0
0
34
390
0.85
0.34
3.5
2.4
11.34
12.94
umol/l
0.93
28
362
13
101
1.30
0.32
2.2
2.0
—
—
—
0
0
182
1761
1.10
0.29
3.9
4.4
11.38
12.03
mm/h
0.33
170
1626
15
121
1.25
0.29
4.9
3.9
33.49
47.25
%
1.66
15
121
219
2140
1.13
0.29
4.4
4.3
1.25
1.26
mmol/l
0.06
202
1943
133
1269
1.10
0.29
4.5
4.0
0.00
6.01
estimate
0.50
33
270
9
118
0.75
0.28
1.0
1.3
—
—
—
0
0
37
329
1.14
0.28
6.8
6.5
103.41
104.34
mmol/l
0.51
37
329
24
206
1.18
0.27
1.4
1.4
—
—
—
0
0
80
747
1.10
0.27
2.2
2.1
226.69
174.91
u/l
0.27
75
701
190
1846
1.10
0.27
7.5
8.0
78.37
80.37
u/l
0.29
178
1731
32
360
0.87
0.26
3.4
2.4
2.46
2.32
g/l
0.80
27
330
231
2268
1.13
0.26
16.9
15.5
25.75
23.54
mg/l
0.34
186
1838
17
142
1.21
0.25
5.4
6.4
25.59
25.02
mmol/l
0.24
17
137
9
77
1.17
0.24
3.3
2.6
24.93
25.12
mmol/l
—
9
77
60
556
1.10
0.24
2.3
2.4
—
—
—
0
0
76
713
1.09
0.23
4.8
4.1
0.00
0.01
estimate
0.50
31
249
5
38
1.32
0.23
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
85
805
1.08
0.21
2.6
2.9
33.37
30.71
u/l
0.26
76
764
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
206.08
—
0
12
131
1358
0.93
0.21
9.0
10.2
4.30
4.02
e9/l
0.53
117
1182
16
187
0.85
0.21
8.0
6.4
9.94
9.09
mmol/l
0.19
16
180
0
13
0.00
0.21
0.0
8.9
—
39.20
—
0
5
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
4.8
—
165.46
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
49.02
—
0
14
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
1.23
—
0
8
103
1075
0.93
0.19
2.5
2.8
—
—
estimate
—
0
0
112
1078
1.07
0.18
4.7
4.4
36.18
35.79
g/l
0.36
99
1011
7
61
1.15
0.17
1.3
1.4
—
—
—
0
0
94
900
1.07
0.17
3.0
3.3
2.36
2.36
mmol/l
0.03
81
814
132
1280
1.06
0.16
4.4
4.0
0.00
0.01
estimate
0.50
30
255
6
79
0.75
0.15
1.2
1.2
1.70
1.60
g/l
—
6
79
6
80
0.74
0.15
1.2
1.2
1.00
0.91
g/l
—
6
80
99
1026
0.94
0.15
2.0
1.9
1.35
1.32
mmol/l
0.12
78
849
10
84
1.20
0.14
1.9
2.1
—
—
—
0
0
12
138
0.86
0.13
8.0
7.6
17.04
15.61
%
2.17
12
133
9
106
0.84
0.13
2.3
1.3
—
—
—
0
0
129
1257
1.05
0.13
4.6
4.0
0.00
0.00
estimate
-0.00
31
264
12
104
1.16
0.12
5.6
3.5
24.72
24.90
mmol/l
0.06
12
104
50
474
1.07
0.12
3.6
3.9
282.66
180.35
ng/l
0.23
38
378
29
271
1.08
0.10
6.1
6.9
10.77
12.04
kpa
0.89
29
264
29
271
1.08
0.10
6.1
6.9
5.52
5.17
kpa
0.49
29
264
18
197
0.91
0.10
1.9
1.9
—
—
—
0
0
157
1544
1.04
0.09
3.5
3.1
51.90
47.05
u/l
0.26
143
1446
95
975
0.96
0.09
4.6
3.9
0.00
0.05
estimate
1.64
20
223
5
63
0.79
0.08
1.2
1.9
—
—
—
0
0
17
156
1.10
0.08
1.0
1.3
—
42.56
—
0
13
6
72
0.83
0.07
1.2
5.3
37.87
26.66
mg/l
—
6
61
6
72
0.83
0.07
2.0
2.0
206.83
344.74
ug/l
—
6
65
6
72
0.83
0.07
1.2
5.3
54.15
58.92
mg/l
—
6
62
23
245
0.93
0.07
3.0
3.1
0.60
0.79
ug/l
0.96
17
152
8
78
1.03
0.07
1.3
1.3
—
—
—
0
0
7
80
0.87
0.07
1.0
1.3
—
28.74
—
0
5
31
295
1.06
0.07
5.4
4.6
34.43
33.27
%
0.32
23
171
74
722
1.03
0.06
1.6
1.7
25.83
21.09
nmol/l
1.41
60
602
222
2205
1.04
0.05
16.9
15.5
80.00
79.76
ml/min/173m2
0.06
208
2041
133
1316
1.02
0.04
5.6
6.4
9.68
10.66
umol/l
1.04
127
1251
19
181
1.05
0.03
1.2
1.2
93.50
180.89
u/ml
—
6
79
23
221
1.04
0.03
2.2
2.1
3.23
3.36
ratio
0.20
17
183
54
549
0.98
0.02
1.6
1.7
0.80
1.23
mg/l
1.32
42
449
26
252
1.04
0.02
3.7
3.4
—
—
—
0
0
17
177
0.96
0.01
1.9
1.9
—
—
—
0
0
110
1092
1.01
0.01
3.9
3.0
83.83
109.76
ug/l
1.48
104
1013
18
174
1.04
0.00
2.7
3.1
29.55
38.10
u/ml
0.37
18
167
14
138
1.02
0.00
4.1
3.3
0.97
1.21
%
1.05
14
138
16
158
1.01
0.00
8.5
7.0
27.43
24.63
mmol/l
1.45
16
158
32
318
1.01
0.00
4.9
4.6
19.78
21.87
%
0.30
12
157
11
109
1.01
0.00
2.9
3.8
1.75
1.53
%
0.26
11
104
24
239
1.00
0.00
1.8
2.4
27.00
30.28
u/l
0.57
19
198
14
137
1.02
0.00
4.1
3.3
0.58
0.61
%
0.17
14
137
12
125
0.96
0.00
1.2
1.0
—
—
—
0
0
5
55
0.91
0.00
1.6
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
107.29
—
0
7
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.18
—
0
7
7
75
0.93
-0.00
1.0
1.4
—
2.28
—
0
15
0
8
0.00
-0.00
0.0
1.5
—
14.76
—
0
8
8
81
0.99
-0.00
2.5
1.6
—
—
—
0
0
8
80
1.00
-0.00
2.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
77
770
1.00
-0.00
4.0
4.0
6.18
7.87
mg/mmol
0.19
49
451
7
74
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
68.70
—
0
8
7
75
0.93
-0.00
1.0
1.4
—
1.68
—
0
10
0
5
0.00
-0.00
0.0
1.6
—
2.17
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1759.50
—
0
8
5
53
0.94
-0.00
3.4
2.5
18.38
15.72
%
—
5
53
7
72
0.97
-0.00
1.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
60
1.00
-0.00
2.2
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_DEGENMYOPIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_DEGENMYOPIA | 0.986 [0.85, 1.15] | 0.861 |
| Birth year | 0.991 [0.98, 1.0] | 0.057 |
During the follow-up period (1.1.1998 — 31.12.2019), 268 out of 1168 females with H7_DEGENMYOPIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_DEGENMYOPIA | 0.96 [0.72, 1.27] | 0.776 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 478 males with H7_DEGENMYOPIA died.
Mortality risk
Mortality risk for people of age
years, who have H7_DEGENMYOPIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.071% | 0.19% |
| 5 | 0.463% | 1.034% |
| 10 | 1.237% | 2.553% |
| 15 | 2.487% | 4.715% |
| 20 | 4.421% | 8.143% |
Relationships between endpoints
↥Index endpoint: H7_DEGENMYOPIA – Degenerative myopia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data