Hydatidiform mole

O15_PREG_HYDAT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O01
  • Hospital discharge: ICD-9 630
  • Hospital discharge: ICD-8 6342|64592
  • Cause of death: ICD-10 O01
  • Cause of death: ICD-9 630
  • Cause of death: ICD-8 6342|64592

2 out of 7 registries used, show all original rules.

590

4. Check minimum number of events

None

590

5. Include endpoints

None

590

6. Filter based on genotype QC (FinnGen only)

536

Control definitions (FinnGen only)

Control exclude
O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O00-O08
Name in latin
Mola hydatidosa

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4171 4171 -
Only index persons 4060 4060 -
Unadjusted period prevalence (%)
Whole population 0.12 0.12 -
Only index persons 0.15 0.15 -
Median age at first event (years)
Whole population - 30.10 -
Only index persons - 29.99 -

-FinnGen-

Key figures

All Female Male
Number of individuals 536 536 -
Unadjusted period prevalence (%) 0.19 0.19 -
Median age at first event (years) 30.24 30.24 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
553
Matched controls
5530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O01.0
ICD-10 Finland
Classical hydatidiform mole
+∞
181.5
164
*
O01.9
ICD-10 Finland
Hydatidiform mole, unspecified
+∞
178.0
161
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
41.8
157.1
97
28
O02.1
ICD-10 Finland
Missed abortion
+∞
144.2
132
*
O01.1
ICD-10 Finland
Incomplete and partial hydatidiform mole
+∞
133.9
123
*
8502
FHL
Evacuation and abrasion
76.1
123.8
67
10
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
62.3
117.9
66
12
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
+∞
104.6
97
*
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
286.0
95.9
95
*
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
144.8
92.3
96
8
MBA05
NOMESCO Finland
Curettage of uterus after abortion
797.3
72.9
70
*
63420
ICD-8 Finland
Other complications of pregnancy, Missed abotion and missed delivery
+∞
72.5
68
*
6300A
ICD-9 Finland
Hydatidiform mole[MOLA HYDATIDOSA]
+∞
66.0
62
*
O00.1
ICD-10 Finland
Tubal pregnancy
+∞
64.9
61
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
13.1
61.1
61
52
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
331.4
59.5
59
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
5.1
59.2
153
383
Z32.1
ICD-10 Finland
Pregnancy confirmed
5.0
58.5
158
410
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
292.7
53.1
53
*
64592
ICD-8 Finland
Other abortion, Mola hydatidosa cum abortu
+∞
49.7
47
*
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
86.2
36.3
40
5
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
+∞
32.6
31
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
7.1
31.1
49
75
LCH11
NOMESCO Finland
Pharmacologic abortion
39.5
29.7
37
10
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
+∞
27.3
26
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.3
26.6
120
429
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
42.4
26.1
32
8
8501
FHL
Emptying the uterus with suction
+∞
25.2
24
*
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
+∞
24.1
23
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.4
23.0
284
1678
O20.0
ICD-10 Finland
Threatened abortion
7.0
22.4
35
53
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
6.1
22.3
40
70
O02.9
ICD-10 Finland
Abnormal product of conception, unspecified
+∞
22.0
21
*
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
+∞
22.0
21
*
D39.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Placenta
+∞
21.0
20
*
ZXD05
NOMESCO Finland
Urgent procedure
2.4
20.0
204
1092
64199
ICD-8 Finland
Abortion induced for other legal indications, Without mention of sepsis or toxaemia
+∞
18.9
18
*
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
+∞
18.9
18
*
N96
ICD-10 Finland
Habitual aborter
65.4
16.8
19
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
4.9
16.6
37
79
6310A
ICD-9 Finland
Other abnormal product of conception[OVUM ABORTIVUM]
+∞
15.7
15
*
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
+∞
15.7
15
*
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
+∞
15.7
15
*
8511
FHL
Cervical dilation and drainage with suction
+∞
15.7
15
*
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
5.0
15.1
33
69
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
+∞
14.6
14
*
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
82.3
14.6
16
*
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
13.6
13
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
13.5
161
895
SPAT1379
SPAT
Health check-up of pregnant person
2.3
12.6
114
566
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.7
11.9
70
284
ZXE00
NOMESCO Finland
One hour or less
1.9
11.7
233
1536
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.9
11.6
35
95
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
5.7
11.2
21
38
W82
ICPC
Abortion spontaneous
20.5
11.2
16
8
WX400
NOMESCO Finland
Inhalation anesthesy
3.7
11.1
36
103
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.3
11.0
91
433
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.0
10.8
144
825
C58
ICD-10 Finland
Malignant neoplasm of placenta
+∞
10.4
10
*
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
+∞
10.4
10
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.1
10.1
110
584
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.2
10.1
92
456
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.8
9.7
240
1666
V03AF03
ATC
calcium folinate; systemic
56.0
9.7
11
*
LCA10
NOMESCO Finland
Curettage of body of uterus
3.8
9.7
30
83
W78
ICPC
Pregnancy
1.9
9.6
144
855
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.5
9.5
61
258
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
4.6
9.4
22
49
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
8.8
128
752
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.0
8.8
102
554
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
50.8
8.7
10
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.7
8.6
213
1469
O03
ICD-10 Finland
Spontaneous abortion
91.4
8.4
9
*
W79
ICPC
Unwanted pregnancy
13.0
8.4
14
11
O03.3
ICD-10 Finland
Spontaneous abortion, Incomplete, with other and unspecified complications
+∞
8.4
8
*
6320A
ICD-9 Finland
Missed abortion[ABORTUS INHIBITUS (""""MISSED ABORTION"""")]
+∞
8.4
8
*
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
3.1
8.1
34
115
SPAT1196
SPAT
Monitoring of normal pregnancy
2.2
8.0
69
334
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
7.9
105
596
MAA00
NOMESCO Finland
Amniocentesis
3.4
7.5
27
83
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.8
7.3
124
760
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
+∞
7.3
7
*
6370A
ICD-9 Finland
Unspecified abortion, Complicated by genital tract and pelvic infection
+∞
7.3
7
*
LBC21
NOMESCO Finland
Laparoscopic salpingotomy and removal of products of conception
+∞
7.3
7
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.8
7.1
110
656
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.0
132
833
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.8
6.9
34
126
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
8.4
6.9
14
17
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.7
6.7
139
902
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.3
6.5
49
223
SPAT1380
SPAT
Postpartum check-up
1.9
6.4
85
482
6331A
ICD-9 Finland
Ectopic pregnancy, Tubal pregnancy
+∞
6.3
6
*
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
+∞
6.3
6
*
O03.8
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, with other and unspecified complications
+∞
6.3
6
*
O06.1
ICD-10 Finland
Unspecified abortion, incomplete, complicated by delayed or excessive haemorrhage
+∞
6.3
6
*
SPAT1197
SPAT
Extensive health check-up of expecting family
1.8
6.1
110
685

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
125
364
4.14
38.66
9.0
1.7
12620.42
9520.91
u/l
0.20
85
112
98
531
2.03
8.45
1.8
1.4
1172.87
1025.06
mu/l
0.50
78
439
44
206
2.23
5.51
1.3
1.3
—
—
—
0
0
98
638
1.65
4.54
1.3
1.2
—
—
—
0
0
63
380
1.74
3.87
1.3
1.4
—
—
—
0
0
183
1442
1.40
3.34
2.8
2.3
53.95
59.27
u/l
1.00
172
1337
155
1187
1.42
3.33
2.0
1.6
—
—
—
0
0
46
265
1.80
3.31
2.1
1.5
—
—
—
0
0
273
2312
1.36
3.14
2.8
2.5
—
—
estimate
—
0
0
15
57
2.68
2.98
1.9
1.4
39.61
28.22
nmol/l
0.82
15
46
124
931
1.43
2.94
2.1
1.7
—
—
—
0
0
49
299
1.70
2.92
1.6
1.4
114.88
63.19
ug/l
0.75
40
254
92
669
1.45
2.58
1.9
1.8
—
—
—
0
0
359
3224
1.32
2.53
4.6
4.1
3263.50
442.08
e6/l
—
6
39
15
317
0.46
2.40
3.6
5.5
1.10
1.19
mmol/l
0.18
15
311
6
13
4.65
2.27
1.5
1.3
—
—
—
0
0
200
1683
1.30
2.20
4.4
7.6
1.07
1.09
inr
0.39
161
1382
146
1178
1.33
2.18
1.5
1.6
0.77
0.84
mg/l
0.20
117
903
38
238
1.64
2.11
1.6
1.4
—
—
—
0
0
37
231
1.64
2.08
1.5
1.4
1.21
1.27
mm
0.48
19
169
5
10
5.03
2.07
1.2
1.0
—
—
—
0
0
0
56
0.00
2.07
0.0
1.1
—
0.50
—
0
27
144
1168
1.31
2.06
4.2
3.6
1.02
2.34
kg/l
0.50
101
764
0
52
0.00
1.89
0.0
1.5
—
0.35
—
0
39
0
52
0.00
1.89
0.0
1.5
—
6.08
—
0
39
0
52
0.00
1.89
0.0
1.5
—
3.04
—
0
37
0
53
0.00
1.88
0.0
1.5
—
—
—
0
0
36
233
1.58
1.78
1.5
1.4
—
—
—
0
0
250
2207
1.24
1.76
2.0
2.0
—
—
—
0
0
168
1426
1.26
1.66
2.7
2.9
45.02
77.41
ng/l
0.24
79
745
12
59
2.06
1.44
1.8
1.4
—
—
—
0
0
5
16
3.14
1.44
1.0
1.8
—
—
—
0
0
16
88
1.84
1.43
1.5
1.4
—
—
—
0
0
179
1553
1.23
1.43
2.3
2.0
—
—
—
0
0
0
37
0.00
1.35
0.0
1.1
—
—
—
0
0
9
42
2.16
1.34
1.0
1.1
—
—
—
0
0
472
4880
0.78
1.27
4.4
4.3
1.57
1.57
mmol/l
0.03
457
4679
99
819
1.25
1.22
2.0
2.5
64.46
89.31
ug/g
1.14
69
643
146
1260
1.22
1.21
2.3
2.2
2.26
2.61
mg/l
1.95
131
1119
19
117
1.65
1.19
1.9
1.8
3.47
5.17
umol/l
1.05
12
87
171
1503
1.20
1.17
4.7
5.9
—
—
—
0
0
8
153
0.52
1.15
1.4
3.2
25.04
25.54
mmol/l
—
8
147
318
2952
1.18
1.15
3.7
3.2
67.75
69.53
ug/l
0.17
310
2835
5
20
2.51
1.15
1.4
2.1
12.20
24.62
ug/l
—
5
20
82
668
1.27
1.15
1.2
1.2
—
—
—
0
0
12
207
0.57
1.12
1.4
2.4
1.73
4.83
iu/l
—
5
98
478
4922
0.79
1.10
4.8
4.9
2.88
2.85
mmol/l
0.37
461
4724
14
81
1.75
1.10
1.4
1.4
128.67
169.46
au/ml
—
6
27
160
1406
1.19
1.09
2.3
2.0
—
—
—
0
0
163
1435
1.19
1.09
2.6
2.6
—
—
—
0
0
17
265
0.63
1.07
4.1
7.0
—
—
—
0
0
8
149
0.53
1.05
1.4
1.2
—
1244.00
—
0
10
13
213
0.60
1.01
2.6
3.2
129.77
129.30
g/l
0.04
13
207
168
1493
1.18
1.01
1.4
1.3
0.64
1.52
u/ml
2.02
52
425
106
908
1.21
0.95
1.7
1.6
407.68
49938467.51
pmol/l
1.81
90
807
40
305
1.34
0.93
1.1
1.1
—
—
—
0
0
476
4890
0.81
0.93
4.6
4.4
4.86
4.84
mmol/l
0.20
461
4710
45
351
1.31
0.91
3.0
4.2
2.75
11.10
ug/l
1.88
31
271
7
126
0.55
0.89
1.0
1.7
0.65
3.34
ug/l
—
7
115
8
42
1.92
0.89
1.5
1.2
—
—
—
0
0
22
309
0.70
0.87
1.2
1.8
1.24
1.41
g/l
0.39
22
295
163
1467
1.16
0.83
4.2
3.7
0.00
0.00
estimate
0.80
64
548
228
2103
1.14
0.82
3.9
3.3
0.02
0.04
estimate
0.45
52
459
502
4904
1.26
0.81
12.7
12.0
18.15
18.87
mg/l
0.22
406
3936
493
4807
1.24
0.81
5.8
6.0
1.80
1.77
mu/l
0.06
475
4618
210
1928
1.14
0.80
1.7
1.9
104.67
98.15
pmol/l
0.79
96
1048
258
2402
1.14
0.80
6.1
5.5
8.87
9.73
umol/l
1.59
248
2284
174
1578
1.15
0.79
3.3
2.9
0.00
0.02
estimate
1.74
51
474
15
98
1.55
0.79
2.5
2.4
4.93
7.02
pmol/l
1.34
15
98
13
82
1.60
0.78
1.9
2.1
—
—
—
0
0
19
132
1.46
0.77
1.0
1.0
9.51
3.28
u/ml
—
8
62
20
278
0.71
0.76
2.0
2.5
4.47
4.64
kpa
0.13
20
271
85
731
1.19
0.75
2.2
2.4
14.68
14.30
umol/l
0.22
79
684
522
5130
1.31
0.74
11.6
10.9
—
—
—
0
0
27
202
1.35
0.74
2.3
9.6
25.10
24.58
mmol/l
0.47
27
189
444
4302
1.16
0.71
5.0
5.0
14.32
14.38
pmol/l
0.23
426
4090
26
195
1.35
0.70
1.6
1.8
—
—
—
0
0
17
118
1.45
0.70
1.0
1.0
3.76
6.02
u/ml
—
5
49
83
720
1.18
0.68
2.5
3.0
82.28
250.90
ng/l
0.75
44
406
135
1220
1.14
0.65
1.3
1.4
40.43
23.19
iu/ml
0.33
40
381
289
2737
1.12
0.64
4.0
3.6
0.05
0.01
estimate
0.34
65
549
123
1108
1.14
0.62
2.2
2.2
289.56
301.51
umol/l
0.92
110
994
16
113
1.43
0.61
1.6
9.6
1.00
1.28
mmol/l
1.10
16
99
450
4612
0.87
0.61
3.8
3.7
1.20
1.21
mmol/l
0.07
431
4388
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
2.6
—
134.38
—
0
21
26
332
0.77
0.60
2.7
3.2
5.96
5.79
kpa
0.48
26
323
77
672
1.17
0.60
2.2
2.3
2.46
2.44
g/l
0.11
71
627
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
16
114
1.42
0.59
1.2
1.0
—
—
—
0
0
47
559
0.83
0.59
1.5
1.6
—
—
—
0
0
125
1132
1.13
0.59
2.2
1.9
—
—
—
0
0
286
2716
1.11
0.58
4.0
3.6
0.00
2.85
estimate
0.50
67
569
21
275
0.75
0.58
4.2
1.7
—
—
—
0
0
35
428
0.81
0.57
4.4
4.9
0.11
0.16
%
—
9
86
19
141
1.36
0.57
1.1
1.3
291.30
351.55
ug/g
—
10
76
27
339
0.79
0.55
2.7
3.4
7.40
7.39
ph
0.30
12
188
56
479
1.19
0.55
1.2
1.2
—
—
—
0
0
195
2081
0.90
0.53
2.1
1.8
1.28
1.30
mmol/l
0.11
169
1837
13
181
0.71
0.53
2.5
2.4
0.62
0.62
%
0.02
13
181
15
109
1.39
0.51
2.1
4.2
59.60
58.76
%
0.11
15
109
10
145
0.68
0.51
4.9
6.8
—
—
—
0
0
490
4811
1.16
0.51
11.5
12.5
139.87
139.66
mmol/l
1.67
484
4722
97
874
1.13
0.50
1.6
1.5
—
—
—
0
0
73
645
1.15
0.50
2.8
2.8
2.72
3.83
e6/l
1.05
35
290
233
2457
0.91
0.49
2.3
2.5
79.48
76.64
nmol/l
0.80
216
2313
50
429
1.18
0.49
3.7
3.3
—
—
—
0
0
49
420
1.18
0.49
2.8
2.1
6.32
6.14
ph
0.75
36
267
16
211
0.75
0.48
1.3
1.4
0.39
0.25
mg/l
—
7
72
281
2687
1.09
0.47
4.0
3.6
0.00
0.00
estimate
0.80
66
562
33
275
1.21
0.44
1.2
1.1
—
—
—
0
0
50
574
0.86
0.44
1.2
1.4
—
—
—
0
0
129
1192
1.11
0.44
2.8
2.8
0.14
0.34
e6/l
2.39
90
846
445
4353
1.11
0.44
14.3
14.9
13.34
13.43
%
1.02
440
4294
7
51
1.38
0.44
2.9
1.5
8.51
8.99
u/ml
—
7
51
55
482
1.16
0.43
1.6
1.8
—
—
—
0
0
15
113
1.34
0.43
1.1
1.1
—
—
—
0
0
6
94
0.63
0.42
2.5
2.3
5.05
4.94
mmol/24h
—
6
84
8
57
1.41
0.42
1.1
1.2
—
—
—
0
0
8
57
1.41
0.42
1.1
1.2
—
—
—
0
0
8
57
1.41
0.42
1.1
1.2
—
—
—
0
0
8
57
1.41
0.42
1.1
1.2
—
—
—
0
0
61
541
1.14
0.41
1.5
1.3
170.81
149.74
u/ml
0.14
31
238
0
15
0.00
0.41
0.0
1.5
—
70.22
—
0
9
0
15
0.00
0.41
0.0
1.7
—
0.22
—
0
7
346
3565
0.92
0.40
2.8
3.0
30.02
34.39
u/l
1.00
334
3427
26
215
1.22
0.39
2.3
2.2
—
—
—
0
0
122
1133
1.10
0.38
1.3
1.3
2.72
12.72
u/ml
4.12
47
504
9
68
1.33
0.37
1.1
1.1
—
—
—
0
0
80
875
0.90
0.36
1.3
1.4
863.33
584.93
titre
0.30
12
207
46
405
1.15
0.35
2.4
2.4
11.76
25.51
au/ml
—
8
58
9
125
0.72
0.35
3.6
2.1
1.00
1.41
g/l
—
9
110
10
134
0.74
0.35
5.3
2.5
9.59
10.86
mg/l
—
10
125
52
463
1.14
0.34
1.7
2.0
0.00
0.07
estimate
1.05
16
116
457
4642
0.91
0.33
4.3
4.2
5.58
5.66
mmol/l
0.85
441
4407
6
86
0.69
0.33
1.3
1.5
0.93
0.51
g/l
—
6
69
36
412
0.86
0.33
3.9
4.7
0.00
0.13
%
—
9
91
68
619
1.11
0.32
1.4
1.4
28.92
28.82
iu/l
0.01
62
553
68
745
0.90
0.32
1.6
1.5
—
—
—
0
0
36
411
0.87
0.32
3.7
4.5
0.27
0.89
%
1.69
11
99
169
1606
1.08
0.32
2.0
1.5
—
—
—
0
0
130
1380
0.92
0.31
3.5
3.3
7.24
7.34
mmol/l
0.10
114
1217
16
197
0.81
0.31
3.7
3.1
24.16
24.08
mmol/l
0.03
16
197
215
2239
0.93
0.31
9.9
9.8
0.00
0.00
e9/l
0.22
182
1843
41
462
0.88
0.31
2.8
2.4
32.07
38.67
u/l
0.69
29
384
7
53
1.32
0.31
1.4
1.1
94.14
110.00
pmol/l
—
7
53
7
54
1.30
0.30
1.9
2.9
—
—
—
0
0
100
932
1.09
0.30
2.3
2.5
8.50
8.07
e6/l
0.07
90
856
38
429
0.88
0.29
3.8
4.6
0.27
1.06
%
3.17
11
108
10
130
0.76
0.29
4.5
2.1
10.47
10.93
g/l
—
10
122
7
56
1.25
0.29
1.9
1.2
—
—
—
0
0
196
1878
1.07
0.29
3.5
5.4
1.23
1.22
mmol/l
1.39
182
1752
147
1396
1.07
0.28
3.0
3.0
17.05
127.16
e6/l
1.31
105
1046
10
129
0.77
0.28
1.4
9.0
0.77
0.93
%
—
10
118
11
85
1.30
0.28
2.1
4.4
4.16
4.25
e9/l
0.06
11
85
179
1714
1.07
0.27
3.5
3.7
78.29
67.49
e6/l
0.10
119
1115
5
71
0.70
0.26
4.6
1.9
57.20
62.82
%
—
5
71
11
138
0.79
0.26
1.5
8.5
1.42
1.59
%
0.25
11
129
33
371
0.88
0.25
1.9
8.1
14.42
13.54
kpa
0.32
33
355
33
371
0.88
0.25
2.0
8.1
5.19
5.12
kpa
0.13
33
355
198
1907
1.06
0.25
4.3
4.4
37.30
36.82
g/l
0.69
185
1811
131
1246
1.07
0.24
1.3
1.4
1.90
2.11
g/l
1.56
93
836
6
84
0.71
0.24
4.0
2.8
56.68
63.13
%
—
6
84
487
4819
1.09
0.24
11.8
12.6
3.90
3.91
mmol/l
0.23
482
4716
136
1297
1.06
0.23
2.1
2.0
196.85
181.37
u/l
0.06
128
1241
21
181
1.17
0.23
1.9
1.8
—
—
—
0
0
101
956
1.07
0.22
3.3
3.7
—
—
—
0
0
17
144
1.19
0.22
1.0
1.1
0.41
0.97
u/ml
—
7
69
26
294
0.88
0.22
3.8
1.6
—
—
—
0
0
5
42
1.19
0.21
1.2
1.2
—
—
—
0
0
5
42
1.19
0.21
1.6
1.1
1.00
1.05
ratio
—
5
34
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
6.45
—
0
11
26
293
0.88
0.21
3.6
1.6
—
—
—
0
0
26
293
0.88
0.21
3.6
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
3.6
—
0.64
—
0
12
170
1639
1.05
0.21
3.3
3.2
2.35
2.36
mmol/l
0.49
163
1525
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.0
—
22.85
—
0
13
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
117
1225
0.94
0.20
4.0
4.1
5.04
7.34
mg/mmol
0.43
65
730
0
14
0.00
0.20
0.0
1.1
—
0.03
—
0
14
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
26
291
0.89
0.19
3.4
1.7
—
—
—
0
0
51
549
0.92
0.19
2.6
2.1
5.33
5.30
umol/l
0.01
44
474
18
206
0.87
0.18
1.2
1.2
—
—
—
0
0
454
4493
1.06
0.18
5.0
5.0
36.84
37.58
mmol/mol
1.47
433
4300
5
69
0.72
0.17
1.0
1.4
—
—
—
0
0
8
69
1.16
0.16
2.1
1.9
—
—
—
0
0
25
225
1.12
0.16
1.2
2.1
0.00
0.02
estimate
0.80
12
93
64
604
1.07
0.16
2.2
2.4
23.25
23.11
%
0.03
56
565
21
235
0.89
0.16
4.2
1.5
—
—
—
0
0
25
276
0.90
0.15
5.4
7.4
6.56
8.10
mmol/l
0.87
25
269
52
488
1.07
0.15
1.4
1.4
—
—
—
0
0
253
2581
0.96
0.15
5.3
6.2
0.04
0.04
e9/l
0.83
225
2268
15
171
0.87
0.15
1.1
2.0
—
12.76
—
0
7
116
1202
0.96
0.14
1.6
1.6
22.97
21.52
nmol/l
0.48
104
1073
7
90
0.77
0.14
4.4
3.5
0.83
0.93
nmol/l
—
7
78
64
674
0.94
0.14
3.1
2.9
0.85
0.82
mmol/l
0.92
59
644
82
784
1.05
0.14
2.6
2.6
526.36
497.67
mosm/kgh2o
0.54
72
697
8
100
0.80
0.13
8.8
3.2
18.63
27.37
mg/l
—
8
86
8
100
0.80
0.13
8.8
3.2
33.09
31.62
mg/l
—
8
87
236
2314
1.03
0.13
2.4
2.6
—
—
—
0
0
34
316
1.08
0.13
1.7
1.8
243.21
342.97
mu/l
1.58
28
291
273
2685
1.03
0.13
5.2
6.4
0.19
0.18
e9/l
0.80
252
2394
13
148
0.88
0.12
1.2
1.2
—
—
—
0
0
22
200
1.10
0.12
1.7
2.7
7.41
7.42
ph
0.58
17
170
238
2338
1.03
0.12
5.3
6.2
2.99
2.76
%
1.04
225
2207
16
143
1.12
0.11
1.0
1.0
2.39
1.34
u/ml
—
5
55
254
2580
0.97
0.11
5.3
6.2
0.53
0.53
e9/l
0.19
226
2270
36
338
1.07
0.11
1.3
1.2
—
—
—
0
0
12
136
0.88
0.11
1.2
1.3
—
—
—
0
0
359
3627
0.97
0.10
7.5
7.2
71.11
74.07
u/l
1.12
342
3468
54
565
0.95
0.10
1.2
1.4
—
—
—
0
0
28
300
0.93
0.10
1.1
1.1
0.85
0.88
g/l
0.32
28
300
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
16
145
1.11
0.09
1.1
1.3
—
—
—
0
0
6
56
1.07
0.08
1.0
1.5
—
—
nmol/l
—
0
0
32
302
1.06
0.08
1.4
1.3
181.58
216.28
miu/ml
—
10
161
214
2108
1.02
0.08
4.4
6.1
1.23
1.22
mmol/l
1.70
186
1836
30
318
0.94
0.08
3.3
3.1
—
—
—
0
0
5
62
0.80
0.08
1.0
1.2
10.74
27.11
u/l
—
5
55
220
2169
1.02
0.08
3.5
3.2
6.20
6.22
ph
0.10
140
1278
5
65
0.77
0.08
8.4
3.7
—
—
—
0
0
255
2581
0.98
0.08
3.2
4.1
6.15
6.37
mmol/l
1.08
234
2387
22
205
1.08
0.08
1.3
1.2
—
—
—
0
0
516
5142
1.05
0.07
10.7
10.5
23.01
23.64
u/l
0.55
510
5045
23
215
1.07
0.07
1.7
2.4
50.30
124.22
ng/l
2.10
23
188
6
73
0.82
0.07
1.0
1.1
—
—
—
0
0
15
137
1.10
0.07
1.0
1.1
—
—
—
0
0
15
137
1.10
0.07
1.0
1.1
—
—
—
0
0
133
1356
0.97
0.07
3.6
4.3
—
—
—
0
0
27
286
0.94
0.07
1.5
2.1
8.60
6.94
iu/ml
—
6
63
237
2399
0.98
0.07
5.4
6.1
54.55
56.69
%
2.53
228
2302
7
80
0.87
0.07
1.3
1.4
1.80
1.69
nmol/l
—
7
75
178
1754
1.02
0.07
2.8
3.0
26.94
28.14
u/l
0.17
172
1660
47
487
0.96
0.06
4.4
5.2
1.03
1.05
mmol/l
0.25
40
445
26
247
1.06
0.05
1.7
1.6
9.76
10.01
u/ml
—
9
63
40
415
0.96
0.05
1.3
1.2
—
—
—
0
0
61
595
1.03
0.05
1.9
1.6
1303.63
1194.14
nmol/l
0.51
53
465
62
605
1.03
0.04
1.4
2.0
—
—
—
0
0
61
624
0.97
0.04
1.4
1.7
3.46
3.47
mmol/l
0.02
39
427
11
101
1.09
0.04
2.3
2.8
25.32
24.82
mmol/l
0.83
11
93
28
291
0.96
0.04
1.1
1.1
1.61
1.62
g/l
0.08
28
291
244
2424
1.01
0.03
5.3
6.2
30.89
29.32
%
1.89
231
2323
15
159
0.94
0.03
2.4
11.5
16.94
15.59
%
1.60
15
149
34
330
1.03
0.03
2.9
3.1
1.25
1.23
mmol/l
0.87
29
283
22
211
1.04
0.03
6.5
2.1
—
—
—
0
0
14
132
1.06
0.02
1.9
2.8
—
—
—
0
0
119
1202
0.99
0.02
3.3
3.5
30.72
36.44
mg/l
0.18
70
738
38
372
1.02
0.01
3.2
2.8
7.38
7.34
ph
2.64
29
269
515
5142
1.02
0.01
14.2
14.5
66.67
67.08
umol/l
0.26
510
5100
16
153
1.05
0.01
1.0
1.0
6.38
3.41
u/ml
—
5
76
236
2350
1.01
0.01
5.4
6.3
8.67
8.34
%
0.84
223
2225
36
367
0.98
0.01
2.0
8.3
7.43
7.41
ph
0.54
25
218
11
104
1.06
0.01
1.7
1.4
—
—
—
0
0
12
126
0.95
0.00
6.5
2.0
—
—
—
0
0
68
686
0.99
0.00
1.3
1.3
—
—
—
0
0
265
2644
1.00
0.00
5.1
6.2
1.95
1.98
e9/l
0.15
244
2383
14
137
1.02
0.00
1.9
3.4
432.86
345.38
mg/l
—
7
55
25
254
0.98
0.00
3.9
2.6
57.49
76.00
e9/l
—
10
178
20
203
0.98
0.00
1.7
1.4
—
—
—
0
0
62
625
0.99
0.00
3.3
3.2
8.29
4.74
e9/l
0.34
50
563
10
98
1.02
0.00
1.0
1.2
—
—
—
0
0
130
1304
1.00
0.00
3.4
3.7
7.40
7.40
ph
0.07
101
922
17
169
1.01
0.00
1.1
1.1
—
—
—
0
0
30
299
1.00
0.00
2.0
9.3
127.27
119.05
g/l
2.24
30
290
234
2338
1.00
0.00
5.4
6.3
0.69
0.70
%
0.16
219
2198
155
1549
1.00
0.00
5.4
6.3
—
—
—
0
0
289
2893
1.00
0.00
8.9
9.1
3.71
3.90
e9/l
0.99
264
2562
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
77.55
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
20.35
—
0
6
8
89
0.90
-0.00
1.0
1.4
—
58.08
—
0
6
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
65
0.92
-0.00
1.3
14.5
103.67
104.84
mmol/l
—
6
58
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
10.8
—
4.85
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
35.80
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
1.34
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
68.57
—
0
7
7
76
0.92
-0.00
1.1
1.3
—
—
—
0
0
8
80
1.00
-0.00
1.1
1.2
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
13.68
—
0
5
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
9
91
0.99
-0.00
2.2
2.2
—
—
—
0
0
6
60
1.00
-0.00
2.2
1.9
—
—
—
0
0
6
65
0.92
-0.00
1.3
14.5
10.17
11.50
mmol/l
—
6
58
5
51
0.98
-0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_PREG_HYDAT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PREG_HYDAT.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_PREG_HYDAT – Hydatidiform mole

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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