No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditions
|
1509 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
528 |
4. Check minimum number of eventsNone |
528 |
5. Include endpointsNone |
528 |
6. Filter based on genotype QC (FinnGen only) |
478 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
Deep bite that required surgery
based on the number of shared cases.
Similar with more cases:
- Bilateral sagittal split ramus osteotomy operation
- LeFortI or BSSO operation
- Deep bite
- Anomalies of dental arch relationship, including avohilmo
- Dentofacial anomalies [including malocclusion]
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2875 | 1851 | 1018 |
| Only index persons | 2854 | 1841 | 1013 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.06 | 0.07 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 37.45 | 37.25 | 37.86 |
| Only index persons | 37.48 | 37.25 | 37.91 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 478 | 337 | 141 |
| Unadjusted period prevalence (%) | 0.10 | 0.12 | 0.06 |
| Median age at first event (years) | 40.25 | 39.80 | 41.35 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 500
- Matched controls
- 5000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.13
ICD-10 Finland
Retrognaty, mandibular
953.7
307.7
426
30
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
182.2
307.7
266
31
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
310.1
307.7
379
50
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
139.9
307.7
174
19
SJC10
NOMESCO Finland
Orthodontic band in one tooth
326.9
307.7
339
32
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
151.7
307.7
239
30
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
245.6
307.7
335
41
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
310.6
307.7
352
38
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
406.1
307.7
402
50
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
149.2
307.7
245
32
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
+∞
307.7
500
11
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
354.1
307.7
266
16
K07.23
ICD-10 Finland
Deep bite
+∞
307.7
500
42
EB1MA
NOMESCO Finland
Cephalometry with X-ray
158.0
307.7
277
39
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
145.6
307.7
346
76
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
199.0
307.7
305
39
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
60.5
307.7
243
77
SBB10
NOMESCO Finland
Dental impressions
128.7
307.7
426
214
SXC05
NOMESCO Finland
Other oral or dental procedure
25.9
297.3
261
202
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
65.5
292.7
167
38
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
34.1
291.4
209
103
SAA04
NOMESCO Finland
Special examination of mouth
29.3
288.8
226
137
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
80.4
279.1
152
27
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
141.9
269.0
135
13
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
58.1
230.0
133
31
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
44.1
229.2
143
45
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
60.9
229.0
131
29
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
17.9
172.7
160
128
EBB10
NOMESCO Finland
Insertion of dental implant
52.8
167.7
98
23
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
10.7
161.0
270
495
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
27.3
150.0
108
50
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
81.2
130.5
70
10
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
12.1
127.7
151
173
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
44.1
118.8
72
19
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
38.7
116.2
73
22
EBB15
NOMESCO Finland
Insertion of dental implant abutment
66.6
115.6
64
11
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
44.3
114.1
69
18
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
8.5
103.3
166
275
SPC20
NOMESCO Finland
Implant borne crown
58.4
100.5
57
11
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
12.7
100.5
108
106
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
580.3
99.1
95
*
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
29.0
98.9
68
27
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
197.4
94.9
96
6
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
189.8
91.6
93
6
K07.24
ICD-10 Finland
Open bite
27.7
87.5
61
25
K07.60
ICD-10 Finland
Snapping jaw
8.2
82.9
130
206
SAA03
NOMESCO Finland
Extended examination of mouth
6.8
81.2
388
1694
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
37.8
76.5
48
14
WZC00
NOMESCO Finland
Treatment plan or consultation
5.5
75.6
333
1332
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
17.8
71.2
60
38
EEC05
NOMESCO Finland
Le Fort I osteotomy
151.6
63.6
66
5
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
151.6
63.6
66
5
SXC03
NOMESCO Finland
Other oral or dental procedure
29.3
63.4
43
16
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
4.8
61.3
345
1584
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
651.9
60.0
58
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.1
58.5
120
246
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
17.1
51.8
44
28
K00.00
ICD-10 Finland
Hypodontia
17.5
50.1
42
26
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
20.1
49.6
39
21
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
76.9
49.2
55
8
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
12.0
48.5
51
47
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
15.9
46.4
41
28
K07.10
ICD-10 Finland
Asymmetry of jaw
86.4
42.7
47
6
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
10.1
40.7
48
52
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
216.9
39.4
40
*
K01.0
ICD-10 Finland
Embedded teeth
10.0
38.9
46
50
EBA10
NOMESCO Finland
Operative extraction of tooth
3.8
38.7
159
551
K07.14
ICD-10 Finland
Retrognaty, maxillary
111.4
38.3
41
*
Z3229
NOMESCO Finland
Other healthcare associate professional
5.9
38.2
75
145
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
86.9
36.4
40
5
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
6.5
34.4
60
103
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
7.9
34.1
49
68
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
349.0
33.3
33
*
ZXE20
NOMESCO Finland
More than three and less than five hours
4.2
32.2
101
287
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
8.8
31.7
41
50
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
91.1
31.1
34
*
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
40.9
30.7
38
10
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
164.9
30.0
31
*
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
309.0
29.1
29
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.5
28.7
60
122
SPC10
NOMESCO Finland
Standard dental crown
11.3
28.0
30
28
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
40.4
27.4
34
9
EB1S1
NOMESCO Finland
Photography of teeth
42.6
26.1
32
8
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.8
26.1
63
145
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
3.2
25.3
123
462
SJE90
NOMESCO Finland
Orthodontic finishing
51.1
24.5
29
6
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
10.2
24.3
28
29
EB1WA, ,
NOMESCO Finland
32.9
24.0
31
10
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
125.8
22.8
24
*
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
65.6
22.1
25
*
ZXA10
NOMESCO Finland
Bilateral
3.1
21.9
108
406
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
114.8
20.7
22
*
OIKK, ,
NOMESCO Finland
7.4
19.7
29
41
K01.17
ICD-10 Finland
Retained molar with obstruction in the lower jaw
5.1
19.3
42
88
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
23.7
19.3
27
12
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
24.8
18.8
26
11
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
17.9
156
778
J01CE02
ATC
phenoxymethylpenicillin; oral
2.7
16.8
408
3116
SAA02
NOMESCO Finland
Basic examination of mouth
2.7
16.4
416
3219
EDC30
NOMESCO Finland
Genioplasty
+∞
15.7
15
*
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.2
15.0
168
923
SPC08
NOMESCO Finland
Implant crown
25.9
14.8
20
8
SPC09
NOMESCO Finland
Implant crown, demanding
82.6
14.6
16
*
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
43.8
14.2
17
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.2
14.2
39
99
SPA02
NOMESCO Finland
Preparation for dental prosthetics
4.9
14.0
31
66
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
77.3
13.6
15
*
SDA02
NOMESCO Finland
Periodontal treatment, brief
2.0
13.5
229
1464
SPAT1324
SPAT
Screening procedure
2.1
12.8
149
825
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
12.7
12.7
22
18
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
12.6
197
1214
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
133.2
12.5
13
*
K07.33
ICD-10 Finland
Crowding of tooth or teeth
38.6
12.3
15
*
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
9.6
12.1
24
26
EB1TW
NOMESCO Finland
3D modelling of dentition
27.5
12.1
16
6
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
27.5
12.1
16
6
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
13.8
12.0
20
15
SAA01
NOMESCO Finland
Simple examination of mouth
2.4
11.9
422
3457
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
122.7
11.5
12
*
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
5.3
11.4
23
45
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
3.4
11.4
42
131
SPB20
NOMESCO Finland
Temporary bridge
20.6
11.2
16
8
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.9
10.8
32
86
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
61.3
10.7
12
*
SCA02
NOMESCO Finland
Preventive oral health care
2.5
10.6
74
327
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
2.0
10.1
149
888
SDA03
NOMESCO Finland
Periodontal treatment
1.8
9.6
251
1789
EDW99
NOMESCO Finland
Other operation on mandible
101.9
9.4
10
*
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.9
9.4
175
1122
G50.1
ICD-10 Finland
Atypical facial pain
7.3
9.1
21
30
WX402
NOMESCO Finland
General anaesthesia
1.9
9.0
130
766
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
19.0
9.0
13
7
EMAK, ,
NOMESCO Finland
3.4
8.9
33
103
K07.61
ICD-10 Finland
Cracking jaw joint
4.0
8.8
25
65
SCA01
NOMESCO Finland
Preventive oral health care, short
1.8
8.6
180
1191
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
8.5
232
1654
WX704
NOMESCO Finland
Intubation
2.5
8.5
55
235
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
8.1
8.4
18
23
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
13.1
8.4
14
11
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
8.3
29
87
TEG00
NOMESCO Finland
Punction of mandibular joint
33.9
8.1
10
*
ECU00
NOMESCO Finland
Removal of implant or external fixation device from alveoli
33.9
8.1
10
*
SCF02
NOMESCO Finland
Preventive oral care by dental hygienist
3.6
8.1
27
79
L07
ICPC
Jaw symptom/complaint
6.3
7.9
20
33
N02BE01
ATC
paracetamol; systemic, rectal
2.3
7.8
449
3954
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
45.7
7.7
9
*
ECA30
NOMESCO Finland
Excision of lesion of gingiva
12.1
7.6
13
11
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
25.4
7.6
10
*
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
81.3
7.4
8
*
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
3.7
7.4
23
64
XX2XX, ,
NOMESCO Finland
+∞
7.3
7
*
K07.05
ICD-10 Finland
Micrognatia (hypoplasia) of both jaws
+∞
7.3
7
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
7.3
7
*
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
16.0
7.3
11
7
K07.68
ICD-10 Finland
Other disorders of the jaw joint
8.1
7.1
15
19
N03AX16
ATC
[U] pregabalin
1.8
7.0
110
662
J01FF01
ATC
clindamycin; systemic
1.8
6.8
138
894
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
40.6
6.8
8
*
R06.5
ICD-10 Finland
Mouth breathing
2.3
6.6
54
255
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.5
6.6
41
171
K06.00
ICD-10 Finland
Local gingivore traction
3.5
6.5
22
65
ECB10
NOMESCO Finland
Reconstruction of gingiva
70.7
6.4
7
*
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
8.3
6.4
13
16
EDC45
NOMESCO Finland
Reconstruction of mandible using bone graft
+∞
6.3
6
*
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
+∞
6.3
6
*
SFA00
NOMESCO Finland
Small restoration
1.9
6.2
81
458
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
7.8
6.2
13
17
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
12.7
6.1
10
8
SPA60
NOMESCO Finland
Fitting of intermediary dental prosthesis structures, 1 to 3 units
8.8
6.1
12
14
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
279
2024
1.86
10.31
2.2
2.7
—
—
estimate
—
0
0
247
1807
1.73
8.17
3.1
3.0
0.11
0.02
estimate
0.69
47
405
167
1231
1.54
4.66
3.4
3.2
0.00
0.01
estimate
1.08
55
462
370
3228
1.56
4.54
3.9
3.9
7.62
8.96
mm/h
1.76
362
3085
179
1370
1.48
4.07
2.3
2.6
0.02
0.02
estimate
0.01
48
391
280
2340
1.45
3.98
3.4
3.2
0.00
3.17
estimate
0.50
58
475
143
1050
1.51
3.97
3.8
3.1
1.02
1.02
kg/l
0.03
96
687
276
2314
1.43
3.77
3.4
3.2
0.02
0.00
estimate
0.41
59
472
44
243
1.89
3.62
1.5
1.5
—
—
—
0
0
276
2352
1.39
3.23
3.4
3.2
0.00
0.01
estimate
0.50
55
450
167
1332
1.38
2.84
2.5
2.9
13.52
23.26
ng/l
1.74
79
699
98
714
1.46
2.76
1.4
1.6
61538892.98
52147662.64
pmol/l
0.05
91
652
49
309
1.65
2.62
1.4
1.4
—
—
—
0
0
29
157
1.90
2.58
1.0
1.1
7.94
2.15
eliau/ml
—
5
26
26
137
1.95
2.50
1.0
1.1
0.94
2.82
u/ml
1.09
11
76
464
4419
1.69
2.44
10.5
12.2
19.04
20.57
mg/l
0.39
375
3522
46
292
1.63
2.41
1.6
1.5
341.51
281.11
mu/l
0.39
41
264
38
232
1.69
2.31
2.1
1.9
—
—
—
0
0
457
4347
1.60
2.28
9.9
12.7
3.93
3.93
mmol/l
0.01
452
4260
156
1865
0.76
2.09
2.0
1.9
1.40
1.41
mmol/l
0.06
142
1672
57
397
1.49
2.02
4.3
5.1
—
—
—
0
0
20
109
1.87
1.80
1.1
1.1
9.77
2.57
u/ml
0.48
11
55
39
570
0.66
1.75
2.4
2.4
4.39
3.53
e6/l
0.25
22
238
435
4144
1.38
1.66
4.0
4.1
5.55
5.74
mmol/l
5.03
419
3945
452
4336
1.44
1.63
9.9
12.6
139.99
139.73
mmol/l
2.20
446
4265
21
121
1.77
1.61
1.2
1.4
18.52
23.23
u/l
0.34
13
104
435
4150
1.37
1.59
5.4
5.4
1.71
1.76
mu/l
0.47
424
4000
20
116
1.75
1.51
1.0
1.1
0.73
1.18
u/ml
—
9
60
127
1057
1.27
1.50
1.6
1.6
—
—
—
0
0
480
4674
1.67
1.46
9.7
10.4
27.73
27.49
u/l
0.11
474
4609
124
1034
1.26
1.44
1.7
1.8
0.71
0.89
mg/l
0.70
90
791
152
1299
1.24
1.43
2.4
2.7
55.11
58.74
u/l
0.40
143
1238
82
650
1.31
1.41
3.7
3.4
19.81
22.28
%
0.56
27
217
14
75
1.89
1.35
1.4
3.8
21.80
22.43
mg/l
—
9
55
0
37
0.00
1.35
0.0
1.2
—
—
—
0
0
9
173
0.51
1.31
1.2
1.5
—
—
—
0
0
8
34
2.37
1.29
1.0
1.1
1490.75
1706.32
miu/ml
—
8
34
380
3594
1.24
1.25
4.8
4.5
14.42
14.39
pmol/l
0.08
370
3419
31
213
1.49
1.24
1.2
1.3
11.83
10.10
u/l
0.22
24
173
107
895
1.25
1.21
2.5
2.1
—
—
—
0
0
146
1265
1.22
1.19
1.7
1.6
—
—
—
0
0
16
94
1.73
1.18
1.4
1.8
—
—
—
0
0
51
388
1.35
1.18
2.1
2.6
12.59
13.68
nmol/l
0.44
51
373
0
35
0.00
1.15
0.0
1.1
—
42.21
—
0
35
437
4212
1.30
1.14
8.3
10.7
91.50
91.53
ml/min/173m2
0.01
410
3844
248
2266
1.19
1.13
3.7
4.9
6.05
6.41
mmol/l
3.56
226
2108
7
30
2.35
1.12
1.4
3.6
433.86
479.07
u/ml
—
7
30
114
971
1.23
1.10
2.5
2.2
—
—
—
0
0
48
619
0.75
1.09
1.9
3.5
0.86
0.82
mmol/l
1.13
43
595
45
342
1.35
1.06
3.9
11.0
1.03
0.88
mmol/l
0.09
26
285
433
4178
1.27
1.05
3.9
3.8
1.30
1.29
mmol/l
0.07
421
4001
44
335
1.34
1.03
2.5
2.1
7686.84
3853.05
u/l
0.32
21
147
0
30
0.00
0.97
0.0
1.7
—
—
—
0
0
63
511
1.27
0.95
3.1
2.5
0.60
0.66
ug/l
0.36
23
248
338
3198
1.18
0.93
6.2
7.7
72.80
75.66
u/l
1.05
327
3071
9
52
1.74
0.93
1.2
1.6
23.14
22.52
nmol/l
—
9
47
17
254
0.66
0.91
1.4
1.6
—
—
—
0
0
35
264
1.35
0.89
1.3
1.4
213.59
240.19
miu/ml
0.19
17
141
32
238
1.37
0.88
1.3
1.6
—
—
—
0
0
212
1944
1.16
0.87
2.0
2.6
77.16
74.07
nmol/l
1.01
205
1841
11
64
1.73
0.86
1.6
1.9
6.92
7.82
mmol/l
0.72
11
64
107
929
1.19
0.86
1.3
1.3
11.64
10.28
u/ml
0.08
62
389
24
171
1.42
0.84
1.9
1.7
4.33
7.61
u/ml
—
8
51
14
89
1.59
0.82
1.0
1.1
4.94
1.75
—
5
24
0
25
0.00
0.79
0.0
1.7
—
—
—
0
0
17
245
0.68
0.78
1.9
1.4
0.98
0.93
ratio
0.25
12
152
17
245
0.68
0.78
1.9
1.4
1.26
1.16
ratio
0.16
12
152
17
245
0.68
0.78
1.9
1.4
1.05
1.23
ratio
0.46
12
152
0
27
0.00
0.77
0.0
1.1
—
—
—
0
0
55
452
1.24
0.76
1.3
1.3
27.31
26.22
iu/l
0.08
47
392
370
3552
1.16
0.75
3.5
3.6
—
—
—
0
0
9
54
1.68
0.75
1.9
1.4
—
—
—
0
0
17
242
0.69
0.74
1.8
1.4
—
—
—
0
0
115
1019
1.17
0.73
1.3
1.3
25.92
26.48
iu/ml
0.02
33
322
5
25
2.01
0.73
1.2
1.5
5.62
6.33
mmol/l
—
5
25
20
143
1.42
0.71
1.5
1.4
0.30
0.40
nmol/l
0.44
15
115
24
180
1.35
0.66
1.2
1.2
—
—
—
0
0
32
399
0.79
0.61
1.5
1.7
—
—
—
0
0
7
112
0.62
0.58
1.9
1.7
0.13
1.16
ug/l
—
7
106
0
23
0.00
0.58
0.0
1.7
—
—
—
0
0
7
115
0.60
0.58
2.0
1.5
—
—
—
0
0
54
630
0.84
0.56
2.4
2.3
2.08
1.00
e6/l
0.49
37
302
6
37
1.63
0.55
1.0
1.1
—
—
—
0
0
11
158
0.69
0.53
1.6
1.6
—
—
—
0
0
54
464
1.18
0.52
1.2
1.3
51.25
157.60
u/ml
5.02
22
193
22
280
0.78
0.51
1.2
1.1
1.53
1.54
g/l
0.05
22
280
58
665
0.86
0.50
2.7
3.4
598.00
496.53
ng/l
0.09
29
416
7
109
0.64
0.49
2.0
2.2
147.79
275.07
ug/l
—
7
102
51
443
1.17
0.44
1.5
1.6
1134.02
1184.05
nmol/l
0.20
41
358
23
283
0.80
0.42
1.3
1.2
0.83
0.91
g/l
1.28
23
283
5
32
1.57
0.42
4.8
1.9
1.03
0.76
e9/l
—
5
32
84
761
1.12
0.41
2.1
2.9
577.27
585.31
ng/l
0.01
70
623
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
3.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
3.4
—
—
—
0
0
10
138
0.72
0.41
3.9
3.2
1.00
1.31
mg/l
—
10
129
5
34
1.48
0.40
1.4
2.1
1.20
1.19
mmol/l
—
5
34
5
34
1.48
0.40
1.4
2.1
105.40
105.65
mmol/l
—
5
34
113
1044
1.11
0.40
1.6
2.3
311.77
323.21
umol/l
0.74
106
970
96
1045
0.90
0.39
2.1
2.6
0.15
0.32
e6/l
1.68
77
742
5
35
1.43
0.39
1.2
1.3
193.12
183.04
pmol/l
—
5
35
85
774
1.12
0.39
2.0
2.0
3.74
3.51
ratio
0.65
57
598
20
246
0.81
0.38
1.5
2.3
70.20
68.33
g/l
0.97
20
235
124
1155
1.10
0.37
1.7
2.1
134.14
208.39
u/l
0.72
118
1104
33
384
0.85
0.36
1.5
1.7
—
—
—
0
0
10
134
0.74
0.35
1.0
1.1
—
—
—
0
0
10
133
0.75
0.34
1.0
1.1
—
—
—
0
0
6
46
1.31
0.33
4.7
3.4
234.83
43.79
u/ml
—
6
46
150
1584
0.92
0.33
4.0
6.5
1.21
1.22
mmol/l
0.31
140
1492
36
314
1.16
0.32
1.9
2.4
82.33
74.60
ml/min/173m2
0.88
18
138
15
119
1.27
0.32
2.1
2.1
—
—
—
0
0
65
591
1.11
0.32
1.7
1.7
3.52
3.54
mmol/l
0.03
39
422
447
4412
1.12
0.31
4.6
4.5
4.92
4.81
mmol/l
1.86
438
4258
351
3429
1.08
0.31
3.2
3.3
50.25
41.18
u/l
0.37
344
3335
51
458
1.13
0.31
2.1
2.1
390.96
376.37
nmol/l
0.15
45
435
7
100
0.70
0.31
1.0
1.1
—
—
—
0
0
411
4042
1.09
0.30
4.5
5.0
36.51
37.80
mmol/mol
4.14
395
3898
17
206
0.82
0.29
1.9
1.4
—
—
—
0
0
56
510
1.11
0.27
3.0
2.0
—
—
—
0
0
29
331
0.87
0.27
2.3
2.7
—
—
—
0
0
14
113
1.25
0.27
1.1
1.3
207.29
138.07
e6/l
0.17
14
84
445
4401
1.10
0.25
4.5
4.4
1.50
1.47
mmol/l
0.73
435
4231
49
535
0.91
0.23
1.7
1.9
—
—
—
0
0
107
1013
1.07
0.23
2.0
2.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
130.60
114.42
pmol/l
—
5
38
187
1805
1.06
0.22
4.1
6.9
1.22
1.21
mmol/l
0.15
172
1583
152
1583
0.94
0.22
1.7
1.9
102.66
97.91
pmol/l
0.56
74
850
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
48
441
1.10
0.21
4.7
7.7
105.92
104.62
mmol/l
1.58
48
441
8
103
0.77
0.21
1.3
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
44.12
—
0
12
8
105
0.76
0.21
1.4
1.7
—
—
—
0
0
14
117
1.20
0.20
1.1
1.2
3.60
3.65
mmol/l
0.10
14
110
448
4439
1.09
0.20
4.8
4.8
3.00
2.87
mmol/l
2.65
439
4271
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
11
133
0.82
0.19
1.2
1.3
—
—
—
0
0
30
270
1.12
0.19
2.3
1.7
0.47
0.31
mg/l
0.56
17
127
260
2542
1.05
0.18
6.6
9.5
3.63
3.94
e9/l
2.07
240
2244
66
620
1.07
0.18
3.2
2.1
—
—
—
0
0
105
1004
1.06
0.18
1.8
2.1
2.41
2.64
mg/l
0.49
97
880
28
308
0.90
0.16
3.4
3.3
2.60
1.82
mmol/l
0.70
23
261
6
77
0.78
0.15
1.0
1.1
—
—
—
0
0
168
1633
1.04
0.15
3.3
4.9
38.27
37.25
g/l
2.13
160
1567
20
223
0.89
0.14
1.8
3.3
4.95
5.11
kpa
0.52
20
217
13
112
1.17
0.14
1.8
1.8
—
—
—
0
0
13
112
1.17
0.14
1.1
1.2
2.15
11.63
e6/l
0.77
13
80
13
112
1.17
0.14
1.1
1.2
—
—
—
0
0
19
211
0.90
0.13
1.5
1.6
—
—
—
0
0
131
1272
1.04
0.12
1.4
1.3
0.77
1.94
u/ml
1.69
51
383
14
123
1.14
0.12
1.1
1.4
4.35
2.86
ug/l
0.57
14
112
137
1333
1.04
0.12
2.2
3.2
2.34
2.35
mmol/l
0.76
130
1254
22
201
1.10
0.11
3.7
9.5
23.60
24.87
mmol/l
1.85
22
201
20
182
1.10
0.11
2.0
1.8
—
—
—
0
0
96
991
0.96
0.11
1.4
1.5
22.83
21.05
nmol/l
0.57
87
899
5
47
1.06
0.09
1.0
1.2
—
—
—
0
0
17
186
0.91
0.09
1.8
3.2
1.69
1.18
mmol/l
0.44
11
134
6
57
1.05
0.08
1.2
1.1
—
—
—
0
0
5
60
0.83
0.08
1.0
1.2
—
—
—
0
0
7
68
1.03
0.08
1.3
1.2
—
640.00
—
0
6
16
147
1.09
0.07
1.6
2.2
92.25
94.84
%
0.22
16
141
7
81
0.86
0.07
1.4
1.5
—
—
—
0
0
19
204
0.93
0.07
3.2
2.8
143.58
133.77
g/l
2.19
19
197
210
2125
0.98
0.06
4.7
6.4
9.70
10.51
umol/l
1.03
203
2041
164
1662
0.98
0.05
3.4
3.2
31.21
30.48
u/l
0.10
158
1586
23
243
0.94
0.05
1.2
1.9
2.06
3.71
mg/l
1.37
16
174
390
3918
0.98
0.05
12.2
14.8
13.22
13.35
%
1.82
385
3888
43
417
1.03
0.04
3.2
3.8
28.69
31.40
%
1.06
35
308
10
92
1.09
0.03
1.4
1.7
—
—
—
0
0
14
132
1.06
0.02
1.5
2.4
3.86
3.55
g/l
0.25
14
127
10
93
1.08
0.02
1.0
1.1
—
—
—
0
0
18
173
1.04
0.01
3.2
2.4
0.66
0.61
%
0.47
18
173
10
94
1.07
0.01
1.3
1.5
—
—
—
0
0
12
126
0.95
0.00
1.2
1.2
—
—
—
0
0
31
304
1.02
0.00
1.1
1.0
—
—
—
0
0
126
1266
0.99
0.00
2.6
3.3
8.64
8.42
mmol/l
0.20
119
1123
18
175
1.03
0.00
3.2
2.4
1.43
1.29
%
0.20
18
175
15
146
1.03
0.00
3.7
3.1
26.45
25.14
mmol/l
0.99
15
137
20
197
1.02
0.00
1.4
1.7
—
—
—
0
0
30
302
0.99
0.00
1.6
1.4
—
—
—
0
0
16
161
0.99
0.00
1.4
1.6
47.33
52.68
ug/l
0.52
16
161
107
1068
1.00
0.00
3.1
4.1
5.09
9.70
mg/mmol
0.60
73
679
0
6
0.00
0.00
0.0
3.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
11.7
—
10.10
—
0
6
0
6
0.00
0.00
0.0
1.0
—
0.01
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
7
70
1.00
0.00
1.0
1.1
—
13.97
—
0
38
5
52
0.96
0.00
1.0
2.3
18.42
17.04
%
—
5
52
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
8
82
0.98
0.00
1.6
1.4
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.1
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
46.80
—
0
5
6
69
0.87
-0.00
1.2
1.2
9.73
10.79
u/l
—
6
61
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
87
0.92
-0.00
1.0
1.1
116.25
115.51
%
—
8
79
0
7
0.00
-0.00
0.0
10.0
—
5.81
—
0
7
0
5
0.00
-0.00
0.0
2.2
—
12.72
—
0
5
6
62
0.97
-0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.2
—
—
—
0
0
5
59
0.85
-0.00
1.6
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
9.08
—
0
5
6
66
0.91
-0.00
1.2
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
-0.00
1.1
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
99
0.91
-0.00
2.3
2.5
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.3
—
—
—
0
0
29
290
1.00
-0.00
1.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.1
—
0.71
—
0
7
7
76
0.92
-0.00
1.4
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_DEEP_BITE_SURGERY and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_DEEP_BITE_SURGERY.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_DEEP_BITE_SURGERY – Deep bite that required surgery
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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