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Use of entacapone

PDMED_ENTACAPONE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N04BX02

1 out of 7 registries used, show all original rules.

360

4. Check minimum number of events

Min. number of events 3
360

5. Include endpoints

None

360

6. Filter based on genotype QC (FinnGen only)

311

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 311 111 200
Unadjusted period prevalence (%) 0.07 0.04 0.09
Median age at first event (years) 69.22 67.11 70.38

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
319
Matched controls
3190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N04BX02
ATC
entacapone; oral
+∞
307.7
319
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
+∞
307.7
319
87
G20
ICD-10 Finland
Parkinson disease
4854.7
307.7
316
62
N04BD01
ATC
selegiline; oral
391.1
307.7
227
20
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
5299.2
307.7
316
56
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
727.8
307.7
222
10
N04BC05
ATC
pramipexole; oral
41.9
265.2
212
144
N87
ICPC
Parkinsonism
81.6
226.5
125
25
N04BB01
ATC
amantadine; oral
90.2
161.4
86
13
N04BC04
ATC
ropinirole; oral
293.9
118.6
114
6
N04BD02
ATC
rasagiline; oral
208.6
111.5
110
8
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
259.3
107.9
105
6
193
Kela drug reimbursment
Rasagiline
269.1
97.4
95
5
N06DA03
ATC
rivastigmine; oral, transdermal
11.9
82.5
99
116
N05AH04
ATC
quetiapine; oral
8.6
80.6
149
295
N04AA02
ATC
biperiden; systemic
33.1
72.6
48
17
N03AE01
ATC
clonazepam; systemic
11.8
66.8
77
84
G02CB01
ATC
bromocriptine; systemic
169.1
54.8
56
*
N04BC02
ATC
pergolide; oral
309.3
52.8
52
*
N04BC09
ATC
rotigotine; transdermal
531.7
47.6
46
*
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
86.7
41.1
45
6
XA800
NOMESCO Finland
Neuropsychological investigation
12.2
39.0
41
38
N04BC06
ATC
cabergoline; oral
221.3
38.7
39
*
R25.1
ICD-10 Finland
Tremor, unspecified
12.6
37.8
39
35
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
88.7
35.7
39
5
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
6.2
30.7
59
113
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
45.8
27.4
33
8
Z2445
NOMESCO Finland
Psychologist
10.2
25.7
30
32
A06AD11
ATC
lactulose; oral
3.5
24.9
121
471
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
4.8
23.9
61
149
3320A
ICD-9 Finland
Parkinson's disease, Paralysis agitans
90.2
23.0
25
*
N04BC01
ATC
bromocriptine; oral
+∞
22.1
21
*
N04BX01
ATC
tolcapone; oral
+∞
17.9
17
*
H02AA02
ATC
fludrocortisone; oral
14.5
16.8
28
21
JDB10
NOMESCO Finland
Percutaneous gastrostomy
19.2
16.8
25
14
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
24.9
15.3
21
9
N04BX04
ATC
opicapone; oral
84.1
14.7
16
*
F02.39
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
84.1
14.7
16
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.9
14.7
87
366
R1250
NOMESCO Finland
Evaluation of functional capability
6.9
13.8
22
34
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.4
13.6
154
884
S01.0
ICD-10 Finland
Open wound of scalp
3.4
13.5
55
185
N05BA04
ATC
oxazepam; oral
2.5
13.0
114
580
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.1
12.9
23
40
I95.1
ICD-10 Finland
Orthostatic hypotension
3.9
12.3
39
111
N06AX11
ATC
mirtazapine; oral
2.3
11.8
126
694
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
14.3
11.6
19
14
N19
ICPC
Speech disorder
14.3
11.6
19
14
C07AA05
ATC
propranolol; systemic
2.8
11.5
67
276
XKD06
NOMESCO Finland
Physiologic investigation of micturition
5.0
11.4
25
53
G04BD12
ATC
mirabegron; oral
2.8
11.3
66
273
N06AB04
ATC
citalopram; systemic
2.5
11.1
90
437
SPAT1231
SPAT
Assessment of adjustments needed in living environment
5.7
11.0
21
39
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
13.5
10.8
18
14
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
14.9
10.6
17
12
R47.1
ICD-10 Finland
Dysarthria and anarthria
11.8
10.2
18
16
SPAT1229
SPAT
Assessment of need for aid
3.0
10.0
47
172
N05AH02
ATC
clozapine; systemic
18.2
9.5
14
8
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
5.1
9.4
20
41
R13
ICD-10 Finland
Dysphagia
3.1
9.4
42
149
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.5
9.3
23
54
R4130
NOMESCO Finland
Speech therapy
5.0
9.2
20
42
N30.0
ICD-10 Finland
Acute cystitis
2.5
9.1
64
288
N06AB10
ATC
escitalopram; oral
2.6
9.1
61
269
S72.0
ICD-10 Finland
Fracture of neck of femur
3.1
9.0
40
141
Z02.4
ICD-10 Finland
Examination for driving licence
0.3
8.9
28
761
R53
ICD-10 Finland
Malaise and fatigue
2.1
8.8
106
600
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
51.4
8.7
10
*
XF606
NOMESCO Finland
Ortostatic test
28.4
8.5
11
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.0
8.4
24
63
N04AA01
ATC
trihexyphenidyl; oral
+∞
8.4
8
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.9
8.4
25
68
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
8.2
38
137
I10
ICD-10 Finland
Essential (primary) hypertension
0.5
8.0
129
1830
N05CD07
ATC
temazepam; oral
2.3
8.0
71
354
K59.09
ICD-10 Finland
Constipation, unspecified
2.9
7.9
40
152
N30.9
ICD-10 Finland
Cystitis, unspecified
3.1
7.9
34
118
AA1AD
NOMESCO Finland
CT of head and brain
2.0
7.8
123
763
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
10.4
7.6
14
14
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.4
7.6
28
88
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
7.5
72
371
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
7.4
75
395
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
7.4
64
316
N04BC07
ATC
apomorphine; parenteral
+∞
7.3
7
*
AAW01
NOMESCO Finland
Implantation of intracranial stimulation device
+∞
7.3
7
*
C10AA07
ATC
rosuvastatin; oral
0.3
7.3
27
686
C10AX09
ATC
ezetimibe; oral
0.2
7.2
8
351
N29
ICPC
Neurological sympt/complt other
8.2
7.2
15
19
C10AA05
ATC
atorvastatin; oral
0.5
7.1
64
1120
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.5
7.0
17
39
N03AX12
ATC
[U] gabapentin; oral
2.3
6.8
58
284
D21
ICPC
Swallowing problem
6.7
6.7
16
25
A28
ICPC
Limited function/disability NOS
2.0
6.6
93
550
N06AX03
ATC
mianserin; oral
3.1
6.6
27
91
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
6.5
33
126
N05BA06
ATC
lorazepam; systemic, sublingual
3.0
6.5
29
103
F0230, G20,
ICD-10 Finland
71.2
6.4
7
*
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
27.3
6.3
8
*
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.6
6.2
38
160
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
6.1
124
823
M48.0
ICD-10 Finland
Spinal stenosis
2.1
6.0
60
312
A10BK03
ATC
empagliflozin; oral
0.1
6.0
*
223

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
134
2058
0.40
14.40
3.8
5.6
4.20
4.36
mmol/l
1.46
122
1855
134
2048
0.40
13.98
3.7
5.4
1.37
1.42
mmol/l
0.79
119
1826
126
1975
0.40
13.96
3.3
4.7
1.17
1.25
mmol/l
0.92
112
1748
148
2114
0.44
11.62
4.0
6.4
2.39
2.48
mmol/l
0.84
132
1889
145
2080
0.44
11.35
5.7
7.5
39.23
40.91
mmol/mol
1.53
136
1894
38
888
0.35
8.94
3.6
4.1
3.97
10.13
mg/mmol
2.21
27
575
155
2099
0.49
8.85
4.1
5.8
5.88
6.17
mmol/l
2.13
136
1862
173
2245
0.50
8.38
8.8
13.1
14.15
23.56
u/l
18.51
155
2154
38
858
0.37
8.14
2.7
3.4
27.07
54.93
mg/l
1.60
28
585
40
861
0.39
7.58
2.6
3.3
6.78
7.25
mmol/l
0.31
34
698
40
832
0.41
6.86
1.6
2.0
1.18
1.30
mmol/l
0.64
30
656
189
2311
0.55
6.02
33.1
30.4
6.53
6.96
e9/l
2.33
182
2237
189
2310
0.55
5.99
33.4
30.4
244.77
236.00
e9/l
1.20
184
2247
189
2310
0.55
5.99
33.1
30.4
4.29
4.37
e12/l
1.32
182
2235
156
1995
0.57
5.60
4.4
5.3
1.92
2.05
mu/l
0.63
144
1756
70
1083
0.55
4.75
5.2
5.9
5.14
3.70
ug/l
0.28
64
947
184
2196
0.62
4.21
19.8
18.5
—
—
—
0
0
36
662
0.49
4.13
3.6
3.0
302.10
366.17
umol/l
3.23
30
549
70
1040
0.58
3.91
3.0
3.5
1473.83
1985.04
ng/l
0.49
61
893
18
68
2.75
3.63
3.4
4.5
27.17
34.15
mg/l
0.45
13
51
149
1836
0.65
3.61
5.3
8.6
84.52
82.38
u/l
0.20
135
1720
186
2186
0.64
3.59
24.0
20.6
29.95
27.54
mg/l
0.42
167
1884
0
89
0.00
3.55
0.0
1.3
—
—
—
0
0
5
191
0.25
3.53
1.0
1.5
—
—
—
0
0
103
1368
0.64
3.49
4.4
6.7
10.99
12.24
umol/l
0.92
96
1293
130
1626
0.66
3.21
3.4
4.2
14.56
15.11
pmol/l
1.53
114
1420
10
282
0.33
3.19
1.2
1.3
—
—
—
0
0
62
899
0.61
2.97
1.7
2.3
—
—
—
0
0
93
1217
0.67
2.72
6.3
5.9
0.16
0.19
e9/l
1.54
80
1042
64
434
1.59
2.67
3.9
3.4
2.20
1.43
e6/l
0.33
29
228
92
1197
0.67
2.58
6.4
5.8
1.48
1.73
e9/l
3.27
77
1047
83
1101
0.67
2.57
7.5
6.0
8.01
9.09
%
4.32
74
1017
82
1090
0.67
2.56
7.4
5.8
63.14
59.52
%
2.60
74
1023
91
1185
0.68
2.56
6.3
5.7
0.03
0.04
e9/l
1.00
69
996
105
1330
0.69
2.54
9.6
9.5
4.61
4.37
e9/l
0.34
82
1147
83
1099
0.67
2.53
7.5
5.8
2.60
2.75
%
0.33
74
1012
84
1108
0.67
2.51
7.7
6.0
23.33
24.90
%
0.88
75
1034
83
1093
0.67
2.44
7.5
5.9
0.59
0.60
%
0.09
73
1008
91
1177
0.68
2.44
6.3
5.7
0.52
0.62
e9/l
4.81
69
987
44
662
0.61
2.40
3.6
3.8
—
—
—
0
0
77
1023
0.67
2.36
2.6
3.1
143.46
149.28
ug/l
0.06
67
925
83
613
1.48
2.33
4.5
4.2
85.77
82.90
%
0.63
83
602
113
886
1.43
2.32
4.9
3.6
—
—
—
0
0
90
1151
0.70
2.21
4.8
4.7
37.20
45.68
ng/l
0.26
70
933
93
713
1.43
2.14
4.3
3.5
—
0.00
estimate
—
0
5
10
225
0.43
1.97
1.2
1.5
—
—
—
0
0
17
313
0.52
1.92
2.6
4.5
2.59
47.94
ug/l
—
10
269
14
275
0.49
1.92
2.3
2.6
3.79
6.67
ug/l
1.60
14
240
12
248
0.46
1.90
5.5
8.8
—
—
—
0
0
0
51
0.00
1.90
0.0
1.2
—
33.29
—
0
44
11
233
0.45
1.86
3.9
4.3
0.50
0.86
%
—
6
87
10
219
0.44
1.85
4.2
4.4
0.40
0.12
%
—
5
73
5
13
3.89
1.72
1.0
1.0
118.60
136.69
nmol/l
—
5
13
0
46
0.00
1.72
0.0
1.4
—
—
—
0
0
11
224
0.47
1.69
4.4
4.6
0.00
0.21
%
—
5
71
45
625
0.67
1.67
3.0
3.4
0.66
0.89
ug/l
2.01
31
436
11
220
0.48
1.61
3.1
3.3
5.02
5.15
kpa
0.20
11
212
11
218
0.49
1.57
3.0
4.2
0.50
0.45
%
—
6
76
6
139
0.42
1.43
2.3
2.6
—
—
—
0
0
10
197
0.49
1.42
3.8
3.2
123.80
127.79
g/l
—
10
190
33
471
0.67
1.41
4.8
5.5
—
—
—
0
0
118
1376
0.77
1.40
5.5
7.1
1.21
1.21
mmol/l
0.47
105
1159
5
123
0.40
1.40
1.6
1.3
—
—
—
0
0
31
209
1.54
1.36
4.9
2.7
6.23
6.14
ph
0.21
26
157
7
149
0.46
1.35
2.1
3.4
—
—
—
0
0
21
327
0.62
1.33
1.2
1.3
—
—
—
0
0
6
132
0.44
1.31
2.5
3.2
84.50
1713.62
u/ml
—
6
113
40
535
0.71
1.21
1.5
1.7
1.21
1.52
mg/l
0.47
34
439
47
611
0.73
1.19
2.1
1.9
334.03
35366295.45
pmol/l
0.74
40
492
66
815
0.76
1.18
5.4
5.6
—
—
—
0
0
136
1537
0.80
1.18
5.2
5.4
6.27
6.89
mmol/l
5.76
131
1475
17
268
0.61
1.15
2.9
2.9
3.82
4.27
kpa
0.60
17
258
62
769
0.76
1.15
2.4
2.3
3.27
3.17
mg/l
0.07
51
647
21
312
0.65
1.10
2.7
3.7
7.39
7.38
ph
0.29
14
193
106
906
1.25
1.10
4.7
3.7
44.36
131.47
e6/l
0.65
81
711
21
311
0.65
1.09
2.6
3.7
5.99
5.78
kpa
0.33
21
300
30
408
0.71
1.01
1.4
1.5
1.78
2.69
g/l
2.18
12
222
78
649
1.27
1.01
3.4
2.9
5.88
4.01
e6/l
0.55
71
592
91
772
1.25
1.00
4.7
3.5
0.28
0.45
e6/l
1.02
65
581
0
31
0.00
0.97
0.0
1.0
—
—
—
0
0
68
563
1.26
0.92
4.8
4.7
1.02
1.02
kg/l
1.26
52
390
11
181
0.59
0.91
1.2
1.5
—
—
—
0
0
125
1395
0.83
0.88
11.9
18.4
1.28
1.37
inr
1.29
107
1189
14
215
0.64
0.88
2.1
2.5
—
—
—
0
0
11
178
0.60
0.86
9.9
2.6
7.05
10.41
g/l
1.83
11
160
78
909
0.81
0.85
3.3
3.3
2.32
2.34
mmol/l
1.02
73
817
111
980
1.20
0.82
5.2
4.3
233.01
113.15
e6/l
0.86
82
727
0
27
0.00
0.78
0.0
2.4
—
459.93
—
0
14
0
28
0.00
0.76
0.0
1.2
—
—
—
0
0
112
1246
0.84
0.73
4.7
6.4
1.20
1.21
mmol/l
0.25
105
1136
7
39
1.81
0.73
1.0
1.4
—
—
—
0
0
5
26
1.94
0.71
2.4
1.8
0.60
2.25
u/field
—
5
12
7
119
0.58
0.69
3.1
1.2
60.14
385.68
u/ml
—
7
110
109
1209
0.85
0.68
4.8
4.7
35.24
34.53
g/l
0.71
102
1116
91
1023
0.85
0.66
13.9
13.6
0.00
0.00
e9/l
0.69
64
834
13
188
0.68
0.64
1.5
2.3
10.95
12.78
nmol/l
0.28
13
168
14
197
0.70
0.61
1.1
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
0.67
—
0
5
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
2.9
—
—
—
0
0
0
21
0.00
0.60
0.0
2.4
—
485.00
—
0
12
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
35
427
0.80
0.59
4.5
6.4
105.66
104.10
mmol/l
0.82
35
427
7
115
0.60
0.59
2.0
1.4
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
311.14
—
0
14
0
23
0.00
0.58
0.0
1.2
—
0.19
—
0
15
11
160
0.68
0.57
1.0
1.2
—
—
—
0
0
10
66
1.53
0.53
2.7
4.0
—
—
—
0
0
51
588
0.84
0.50
2.3
3.1
2.46
2.46
mmol/l
0.11
45
525
7
110
0.63
0.49
2.1
3.2
4.20
4.25
pmol/l
—
7
96
36
303
1.21
0.45
1.6
1.8
—
—
—
0
0
40
465
0.84
0.44
2.3
3.0
0.83
0.82
mmol/l
0.24
40
435
9
131
0.68
0.44
2.8
2.9
—
—
—
0
0
6
91
0.65
0.43
11.0
5.4
—
—
—
0
0
46
400
1.18
0.42
1.8
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
23.47
—
0
15
0
16
0.00
0.41
0.0
1.1
—
13.32
—
0
6
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
57.83
—
0
12
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
1.28
—
0
13
24
290
0.81
0.39
1.5
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
9
67
1.35
0.38
3.8
4.3
2.27
2.86
mmol/l
—
9
39
5
37
1.36
0.37
1.8
1.2
—
—
—
0
0
111
1186
0.90
0.36
2.5
2.3
82.23
94.61
pmol/l
3.39
84
627
63
694
0.89
0.35
5.8
6.3
—
—
—
0
0
82
755
1.12
0.34
5.1
4.5
0.00
0.01
estimate
0.50
30
261
14
175
0.79
0.31
1.6
1.5
—
—
—
0
0
63
577
1.11
0.29
4.1
3.3
635.13
542.61
mosm/kgh2o
2.71
56
505
53
580
0.90
0.27
1.5
1.4
—
—
—
0
0
5
72
0.69
0.26
2.4
1.3
—
—
—
0
0
27
306
0.87
0.24
1.3
1.4
—
—
—
0
0
90
850
1.08
0.23
2.6
4.4
7.41
7.40
ph
2.56
68
615
107
1018
1.08
0.23
4.6
4.0
6.29
6.23
ph
0.26
70
575
0
11
0.00
0.21
0.0
1.2
—
8.35
—
0
11
0
11
0.00
0.21
0.0
1.6
—
24.01
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
5.74
—
0
12
90
853
1.08
0.21
4.3
4.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
76
716
1.08
0.21
6.5
4.0
0.00
0.14
estimate
0.71
31
234
51
546
0.92
0.18
3.4
4.1
92.35
264.75
ng/l
1.18
40
484
103
988
1.06
0.17
6.3
4.6
0.00
0.05
estimate
1.43
27
247
5
67
0.74
0.17
1.2
1.2
—
2.61
—
0
7
5
70
0.71
0.17
1.2
1.2
—
—
—
0
0
87
831
1.06
0.16
2.1
1.8
20.44
20.51
nmol/l
0.01
75
676
6
78
0.76
0.15
3.7
14.4
—
—
—
0
0
169
1649
1.05
0.15
7.7
5.3
9273.40
2076.70
e6/l
0.64
15
43
56
593
0.93
0.15
1.7
1.8
1246.34
1198.60
nmol/l
0.13
47
439
19
211
0.89
0.13
5.9
3.8
—
—
—
0
0
59
565
1.05
0.10
4.0
4.3
—
0.30
—
0
10
5
63
0.79
0.08
1.2
1.1
—
—
—
0
0
86
840
1.03
0.07
2.3
2.5
—
—
—
0
0
23
217
1.06
0.06
4.9
4.2
—
—
—
0
0
25
238
1.05
0.05
3.8
2.7
0.24
0.61
e6/l
0.45
25
229
125
1267
0.98
0.05
6.2
4.4
0.00
0.00
estimate
-0.00
28
295
38
367
1.04
0.05
5.0
7.0
2.17
1.34
mmol/l
0.62
29
307
114
1124
1.02
0.04
2.5
2.9
—
—
estimate
—
0
0
128
1296
0.98
0.04
6.2
4.5
0.00
1.07
estimate
0.51
30
283
21
201
1.05
0.03
2.3
3.7
—
—
—
0
0
21
219
0.96
0.03
1.1
1.6
—
—
—
0
0
128
1287
0.99
0.01
6.1
4.5
0.00
5.29
estimate
0.50
31
307
11
107
1.03
0.00
3.5
2.0
—
—
—
0
0
5
50
1.00
0.00
1.8
1.3
24.20
175.58
e6/l
—
5
40
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
8.66
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
56.67
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
6.14
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
83.06
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
1695.00
—
0
5
37
370
1.00
-0.00
5.0
7.0
7.42
7.42
ph
0.29
24
228
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
27.71
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
1.18
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
0.55
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
41.00
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
93.59
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
2.33
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
67
0.89
-0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.8
—
5.06
—
0
5
0
5
0.00
-0.00
0.0
3.2
—
1.06
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: PDMED_ENTACAPONE – Use of entacapone

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).