tonsil cancer: Tumors or cancer of the PALATINE TONSIL.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
499 |
4. Check minimum number of eventsNone |
499 |
5. Include endpointsNone |
499 |
6. Filter based on genotype QC (FinnGen only) |
450 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10
- Name in latin
- Neoplasma benignum tonsillae palatinae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Tonsil
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Neoplasms
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2787 | 1600 | 1173 |
| Only index persons | 2614 | 1535 | 1079 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 56.41 | 55.74 | 57.29 |
| Only index persons | 55.84 | 55.41 | 56.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 450 | 267 | 183 |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | 0.08 |
| Median age at first event (years) | 59.70 | 57.16 | 63.40 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 468
- Matched controls
- 4680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.4
ICD-10 Finland
Benign neoplasm: Tonsil
+∞
307.7
453
*
EMB10
NOMESCO Finland
Tonsillectomy
12.1
86.7
96
98
EMA10
NOMESCO Finland
Biopsy of tonsil
175.0
84.2
86
6
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
22.5
59.9
45
22
JDB10
NOMESCO Finland
Percutaneous gastrostomy
28.0
59.5
41
16
C09.0
ICD-10 Finland
Malignant neoplasm: Tonsillar fossa
119.2
49.9
53
5
C09.9
ICD-10 Finland
Malignant neoplasm: Tonsil, unspecified
236.1
42.6
43
*
8070/3-C09.9
ICD-O-3
Squamous cell carcinoma, NOS, of tonsil, NOS
218.1
39.5
40
*
ENA10
NOMESCO Finland
Biopsy of pharynx
200.4
36.3
37
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.8
36.1
73
145
WF002
NOMESCO Finland
Radical radiotherapy
5.8
32.9
65
126
J35.1
ICD-10 Finland
Hypertrophy of tonsils
12.7
31.0
31
26
130
Kela drug reimbursment
Malignant tumour
4.4
29.6
84
221
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.7
25.1
63
150
C09.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tonsil
252.4
23.9
24
*
R07.0
ICD-10 Finland
Pain in throat
4.3
21.6
60
154
A03FA01
ATC
metoclopramide; systemic, rectal
2.7
20.7
156
738
EMB00
NOMESCO Finland
Excision of lesion of tonsil or adenoids
+∞
16.8
16
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
17.5
16.3
25
15
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
20.1
15.7
23
12
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.2
15.2
42
107
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
14.0
146
781
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.3
13.6
55
182
8070/3-C09.0
ICD-O-3
Squamous cell carcinoma, NOS, of tonsillar fossa
+∞
13.6
13
*
A07AA02
ATC
nystatin; oral
3.8
13.6
44
126
R4190
NOMESCO Finland
Nutritional therapy
4.3
12.8
34
84
J35.0
ICD-10 Finland
Chronic tonsillitis
4.2
12.7
35
89
9680/3-C09.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of tonsil, NOS
+∞
12.6
12
*
ZXE00
NOMESCO Finland
One hour or less
2.0
12.5
203
1276
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.3
12.3
48
155
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
4.1
12.3
35
91
A04AA02
ATC
granisetron; systemic, transdermal
3.2
12.2
51
172
R21
ICPC
Throat symptom/complaint
2.2
11.9
118
612
J39.2
ICD-10 Finland
Other diseases of pharynx
14.1
11.5
19
14
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
15.5
11.4
18
12
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
8.6
10.9
23
28
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
10.8
214
1423
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
24.0
10.3
14
6
EHA10
NOMESCO Finland
Biopsy of palate
17.2
9.9
15
9
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
4.6
9.7
23
52
21050
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Tonsil
+∞
9.4
9
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
9.3
188
1244
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
16.0
9.1
14
9
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
7.9
8.7
19
25
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.5
8.6
30
90
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
8.6
163
1051
N02AA05
ATC
oxycodone; systemic
2.0
8.6
102
562
9673/3-C09.9
ICD-O-3
Mantle cell lymphoma of tonsil, NOS
+∞
8.4
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
8.2
148
936
UJC01
NOMESCO Finland
Scopy of lower throat
8.4
8.2
17
21
ZX095
NOMESCO Finland
Combined chemoradiotherapy
12.0
8.1
14
12
D37.08
ICD-10 Finland
Tumor of uncertain or unknown nature in other part of lip, oral cavity and pharynx
34.0
8.1
10
*
J35.9
ICD-10 Finland
Chronic disease of tonsils and adenoids, unspecified
34.0
8.1
10
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
7.4
8.0
18
25
R04.2
ICD-10 Finland
Haemoptysis
3.9
7.9
23
61
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
7.7
32
108
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
7.3
7.5
17
24
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
7.5
183
1261
H02AB02
ATC
dexamethasone; systemic
2.2
7.4
67
332
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.6
7.2
24
70
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
11.2
6.8
12
11
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
40.7
6.8
8
*
XX3DW
NOMESCO Finland
Time consuming IT work
2.2
6.8
63
315
K11.70
ICD-10 Finland
Hypoptyalism
22.9
6.7
9
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
6.7
339
2811
Z2221
NOMESCO Finland
Medical doctor
1.8
6.6
135
878
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
8.9
6.6
13
15
D10.5
ICD-10 Finland
Benign neoplasm: Other parts of oropharynx
70.8
6.4
7
*
Z72.0
ICD-10 Finland
Tobacco use
3.8
6.4
19
51
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
8.3
6.4
13
16
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.2
6.3
54
261
EBA00
NOMESCO Finland
Extraction of tooth
1.7
6.3
174
1227
B37.0
ICD-10 Finland
Candidal stomatitis
7.2
6.3
14
20
JN4BD
NOMESCO Finland
Extensive body CT
2.2
6.2
55
269
J35.8
ICD-10 Finland
Other chronic diseases of tonsils and adenoids
12.7
6.1
10
8
N06AB04
ATC
citalopram; systemic
1.8
6.1
103
633
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
150
748
2.48
17.36
1.7
1.5
—
—
—
0
0
42
110
4.10
14.65
1.3
1.2
—
—
—
0
0
143
747
2.32
14.54
5.7
3.4
0.79
0.82
mmol/l
1.85
137
711
24
29
8.66
11.43
1.3
1.1
—
—
—
0
0
321
2433
2.02
11.03
13.7
10.3
4.00
4.13
e9/l
0.51
276
2147
284
2131
1.85
9.28
6.6
7.3
1.22
1.21
mmol/l
0.72
248
1853
386
3222
2.13
8.94
10.9
8.5
76.38
78.61
u/l
0.68
376
3056
214
1493
1.80
8.72
4.9
3.5
2.37
2.36
mmol/l
1.00
200
1352
296
2276
1.82
8.65
7.6
6.8
10.00
11.37
umol/l
2.85
289
2181
249
1857
1.73
7.73
5.7
5.0
36.04
35.75
g/l
0.35
241
1753
367
3126
1.81
6.43
5.3
4.5
12.35
11.73
mm/h
0.36
345
2917
17
44
3.97
6.04
1.5
1.3
—
—
—
0
0
250
1947
1.61
5.97
6.3
6.4
1.21
1.21
mmol/l
0.10
241
1808
128
851
1.69
5.71
3.9
2.9
2.46
2.45
mmol/l
0.45
117
755
145
1002
1.65
5.56
1.3
1.3
0.61
1.64
u/ml
1.57
36
295
94
580
1.78
5.44
6.2
5.6
1.01
1.03
mmol/l
0.19
87
540
105
675
1.72
5.25
3.5
2.9
1.88
2.33
e6/l
0.32
51
324
163
1175
1.59
5.20
3.7
3.1
0.36
0.45
e6/l
0.28
118
852
111
730
1.68
5.10
3.2
2.8
0.90
0.99
e6/l
0.13
58
378
22
77
2.95
4.99
2.4
3.7
—
3535.87
—
0
8
370
3242
1.67
4.88
5.7
4.4
14.72
14.78
pmol/l
0.19
346
2982
444
4128
2.47
4.74
22.8
18.9
139.47
139.69
mmol/l
0.99
438
4057
429
3939
2.07
4.66
21.0
15.4
81.56
81.21
ml/min/173m2
0.14
411
3657
418
3807
1.92
4.62
6.9
5.4
1.97
1.90
mu/l
0.58
393
3526
444
4134
2.44
4.61
23.1
19.0
3.96
3.97
mmol/l
0.63
438
4054
52
282
1.95
4.50
1.3
1.3
74.95
149.95
u/ml
1.29
17
116
327
2816
1.54
4.30
3.5
3.4
48.37
49.29
u/l
0.06
308
2677
93
611
1.65
4.24
2.4
2.3
21.99
23.15
%
0.34
85
577
28
122
2.38
4.19
1.1
1.1
—
—
—
0
0
295
2494
1.49
4.17
5.1
5.0
6.48
6.71
mmol/l
1.38
289
2364
179
1370
1.50
4.17
3.9
3.2
27.49
112.12
e6/l
1.02
131
1047
232
1871
1.48
4.16
2.2
2.1
101.30
97.40
pmol/l
0.58
126
967
152
1129
1.51
4.07
3.6
2.7
342.10
340.46
umol/l
0.07
135
1001
38
197
2.01
3.75
1.3
1.3
—
—
—
0
0
231
1896
1.43
3.59
2.9
2.5
77.86
77.37
nmol/l
0.09
207
1705
10
21
4.84
3.57
1.6
2.4
—
—
—
0
0
65
407
1.69
3.54
3.0
2.5
30.64
36.05
u/l
0.69
58
336
235
1939
1.43
3.53
3.0
2.8
—
—
estimate
—
0
0
424
3943
1.80
3.47
5.8
5.2
5.90
5.96
mmol/l
0.59
395
3652
142
1070
1.47
3.46
2.5
2.2
3.15
3.03
mg/l
0.18
120
932
101
712
1.53
3.39
2.4
2.3
12.61
13.51
umol/l
0.59
93
669
26
122
2.20
3.32
1.1
1.1
—
—
—
0
0
431
4043
1.84
3.20
21.9
16.0
21.83
23.29
mg/l
0.45
377
3355
448
4260
2.21
3.14
15.5
12.5
26.73
26.09
u/l
0.35
441
4148
94
663
1.52
3.14
2.4
2.3
2.41
2.35
g/l
0.50
87
615
10
25
4.06
3.10
2.7
3.4
0.65
0.72
%
—
10
25
15
56
2.73
3.08
1.9
1.6
—
—
—
0
0
46
274
1.75
3.01
6.3
9.2
24.20
24.49
mmol/l
0.32
46
269
135
1035
1.43
2.95
2.6
2.3
—
—
—
0
0
48
302
1.66
2.60
1.8
1.6
—
—
—
0
0
71
492
1.52
2.57
3.2
2.9
4.82
7.93
umol/l
3.10
62
446
123
951
1.40
2.52
1.7
1.7
0.91
1.26
mg/l
1.52
96
760
73
515
1.49
2.43
1.8
1.8
1.53
1.48
%
0.23
59
449
231
1979
1.33
2.43
10.9
12.2
1.18
1.21
inr
0.35
197
1632
17
77
2.25
2.40
1.7
3.3
5.11
5.07
kpa
0.10
17
77
166
1362
1.34
2.32
2.6
2.6
53.80
64.55
u/l
1.47
152
1285
234
2017
1.32
2.32
3.5
2.9
140.44
121.28
ug/l
0.59
221
1888
96
722
1.41
2.30
2.2
2.0
—
—
—
0
0
7
18
3.93
2.26
1.0
1.3
—
—
—
0
0
453
4373
2.12
2.23
32.3
24.5
254.01
249.73
e9/l
0.66
443
4300
36
219
1.70
2.23
1.5
1.3
—
—
—
0
0
5
9
5.60
2.22
1.0
1.3
—
—
—
0
0
94
709
1.41
2.21
1.9
1.7
1151.06
1207.81
nmol/l
0.24
72
531
453
4375
2.11
2.20
32.2
24.5
4.45
4.49
e12/l
0.99
442
4289
31
183
1.74
2.14
1.2
2.0
1.39
1.43
g/l
0.12
23
162
59
412
1.49
2.08
4.1
3.3
—
—
—
0
0
119
943
1.35
2.07
2.9
2.6
4.38
6.13
e6/l
0.77
105
859
24
133
1.85
2.03
1.5
1.4
—
—
—
0
0
50
340
1.53
2.00
4.4
2.5
65.36
67.26
ml/min/173m2
0.17
28
144
61
433
1.47
1.99
2.9
2.2
403.20
382.83
nmol/l
0.38
56
406
153
1267
1.31
1.95
1.7
1.7
20.58
20.79
nmol/l
0.06
131
1073
11
45
2.48
1.94
2.2
1.8
—
—
—
0
0
0
50
0.00
1.90
0.0
1.1
—
—
—
0
0
0
52
0.00
1.89
0.0
1.1
—
—
—
0
0
8
29
2.79
1.80
2.8
3.0
1159.75
838.66
mg
—
8
29
16
81
2.01
1.76
1.9
1.9
—
—
—
0
0
365
3406
1.33
1.76
26.5
19.7
13.85
13.63
%
1.96
356
3364
5
13
3.87
1.72
4.0
3.1
0.64
0.61
mmol/l
—
5
13
22
126
1.78
1.71
1.7
1.8
—
—
—
0
0
428
4105
1.50
1.67
6.1
6.0
2.73
2.72
mmol/l
0.16
393
3823
250
2234
1.26
1.67
4.3
3.8
0.00
0.00
estimate
-0.00
56
465
423
4049
1.46
1.66
5.4
5.3
4.62
4.66
mmol/l
0.30
386
3780
21
120
1.79
1.65
1.7
1.8
—
—
—
0
0
22
128
1.75
1.63
1.4
1.4
302.07
310.98
ug/g
0.08
15
75
251
2252
1.25
1.59
4.3
3.8
0.00
3.43
estimate
0.50
57
474
11
50
2.23
1.58
1.4
1.2
—
—
—
0
0
17
92
1.88
1.58
1.1
1.4
—
—
—
0
0
253
2275
1.24
1.56
4.4
3.9
0.00
0.69
estimate
0.51
56
446
0
42
0.00
1.53
0.0
1.1
—
—
—
0
0
6
21
2.88
1.51
2.8
1.3
76.33
60.17
ng/l
—
6
21
106
870
1.28
1.42
1.9
1.8
453.81
16049825.10
pmol/l
0.50
86
729
30
198
1.55
1.41
1.1
1.0
—
—
—
0
0
19
111
1.74
1.41
1.9
1.9
1.62
3.98
iu/l
—
5
41
66
510
1.34
1.36
2.2
1.9
—
—
—
0
0
16
90
1.81
1.34
1.8
2.9
13.88
9.00
pmol/l
0.53
16
90
9
43
2.11
1.31
1.2
1.2
—
—
—
0
0
11
55
2.02
1.28
1.8
1.7
—
—
—
0
0
35
245
1.46
1.27
2.1
1.7
—
—
—
0
0
14
77
1.84
1.26
1.2
1.4
—
—
—
0
0
14
77
1.84
1.26
1.2
1.4
—
—
—
0
0
8
38
2.12
1.19
2.6
2.4
—
—
—
0
0
11
57
1.95
1.18
1.5
1.3
0.13
0.18
nmol/l
2.01
11
38
21
134
1.59
1.16
1.4
1.2
—
—
—
0
0
418
4035
1.34
1.14
5.3
5.2
1.45
1.48
mmol/l
0.83
378
3744
12
65
1.87
1.14
1.2
1.4
—
—
—
0
0
7
136
0.51
1.11
1.0
1.7
—
—
—
0
0
17
104
1.66
1.11
1.7
1.7
—
—
—
0
0
22
144
1.55
1.10
2.0
1.6
—
—
—
0
0
19
120
1.61
1.10
1.3
1.2
—
—
—
0
0
20
129
1.57
1.07
1.9
1.8
1075.17
1733.12
u/l
—
8
43
15
91
1.67
1.01
1.6
1.5
—
—
—
0
0
184
1655
1.18
1.01
4.1
3.8
34.94
90.74
ng/l
0.76
128
1176
76
626
1.26
1.00
1.6
1.5
—
—
—
0
0
44
337
1.34
1.00
4.3
3.2
70.75
81.58
ng/l
0.85
39
295
11
61
1.82
0.99
1.2
1.1
—
—
—
0
0
5
23
2.19
0.98
1.0
1.8
—
—
—
0
0
5
23
2.19
0.98
3.6
4.2
69.40
149.70
nmol/l
—
5
23
9
50
1.82
0.97
1.6
2.1
—
—
—
0
0
67
548
1.26
0.95
2.0
1.9
—
—
—
0
0
61
494
1.27
0.93
5.6
8.1
0.26
1.03
mmol/l
0.99
54
431
400
3861
1.25
0.92
4.5
4.4
1.30
1.29
mmol/l
0.12
362
3563
6
28
2.16
0.92
1.8
1.8
—
—
—
0
0
56
452
1.27
0.89
3.6
4.5
11.42
23.29
ug/l
0.51
45
376
25
178
1.43
0.88
1.5
2.0
—
—
—
0
0
164
1481
1.17
0.83
3.6
3.4
28.84
31.47
u/l
0.90
158
1399
11
65
1.71
0.83
1.5
1.3
0.60
29.37
nmol/l
0.49
11
59
6
32
1.89
0.82
2.5
1.6
—
—
—
0
0
51
412
1.27
0.81
3.6
3.4
1.90
1.88
mmol/l
0.01
43
349
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
8
48
1.68
0.79
1.4
1.1
—
94.40
—
0
5
95
824
1.19
0.78
5.9
3.9
291.69
234.82
ng/l
0.15
82
644
17
115
1.50
0.78
2.5
3.1
2.18
2.22
index
0.02
11
72
138
1239
1.16
0.75
4.7
3.9
0.00
0.00
estimate
0.50
54
439
19
133
1.45
0.74
6.3
3.7
2.05
2.68
ratio
—
10
75
9
55
1.65
0.74
1.6
2.0
—
—
—
0
0
16
109
1.48
0.72
1.6
1.6
—
—
—
0
0
18
126
1.45
0.71
1.7
2.5
192.61
193.54
%
0.01
18
121
5
27
1.86
0.68
1.2
2.3
110.80
105.74
%
—
5
27
7
43
1.64
0.67
1.9
1.7
—
—
—
0
0
7
43
1.64
0.67
1.9
1.7
—
—
—
0
0
7
43
1.64
0.67
1.9
1.7
—
—
—
0
0
145
1318
1.15
0.66
2.5
2.1
157.71
231.24
u/l
0.72
135
1250
10
62
1.63
0.65
1.5
1.2
1.80
1.58
u/ml
—
5
19
7
44
1.60
0.65
1.6
1.1
1.22
1.53
nmol/l
—
7
37
17
121
1.42
0.63
1.3
1.3
—
—
—
0
0
399
3885
1.18
0.62
6.6
6.5
38.70
39.40
mmol/mol
1.04
371
3661
9
137
0.65
0.61
1.1
1.1
1.39
1.54
g/l
—
9
137
13
89
1.47
0.58
3.1
4.6
30.93
30.97
mg/l
—
7
66
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
94
840
1.15
0.55
1.5
1.3
37.14
32.98
iu/ml
0.11
19
281
50
425
1.20
0.54
3.7
3.4
5.95
5.78
kpa
0.56
44
412
11
74
1.50
0.54
1.0
1.1
0.67
3.28
u/ml
—
5
39
13
93
1.41
0.48
1.8
1.6
—
—
—
0
0
10
143
0.69
0.48
1.3
1.2
1.00
0.89
g/l
—
10
143
42
356
1.20
0.48
1.8
2.3
12.91
13.33
nmol/l
0.12
35
325
7
47
1.50
0.47
1.7
1.5
—
—
—
0
0
11
77
1.44
0.46
1.9
1.6
—
—
—
0
0
193
1827
1.10
0.42
1.9
2.0
1.35
1.34
mmol/l
0.04
155
1543
5
32
1.57
0.42
1.0
1.2
101.20
105.09
pmol/l
—
5
32
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
10
72
1.40
0.37
1.3
1.5
1.00
0.99
ratio
—
5
46
10
72
1.40
0.37
1.3
1.5
—
—
—
0
0
10
72
1.40
0.37
1.3
1.5
1.16
1.23
ratio
—
5
46
10
72
1.40
0.37
1.3
1.5
1.18
1.13
ratio
—
5
46
178
1696
1.08
0.33
4.2
3.7
0.04
0.02
estimate
0.27
48
391
12
92
1.31
0.32
1.4
1.2
—
—
—
0
0
157
1492
1.08
0.31
3.5
3.4
7.70
7.59
mmol/l
0.10
128
1263
41
364
1.14
0.29
3.3
2.9
4.27
4.43
kpa
0.32
35
352
18
149
1.22
0.28
2.7
1.8
—
—
—
0
0
39
348
1.13
0.27
1.7
1.4
—
—
—
0
0
137
1303
1.07
0.26
3.5
3.3
1615.99
1058.97
ng/l
0.73
111
1102
11
86
1.29
0.26
1.1
1.3
—
163.33
—
0
6
23
197
1.18
0.26
1.5
1.5
0.29
0.31
mg/l
0.04
11
88
19
160
1.20
0.26
2.8
2.0
—
—
—
0
0
52
475
1.11
0.25
8.4
7.1
—
—
—
0
0
25
217
1.16
0.25
2.0
2.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
4891.40
377233.44
e6/l
—
5
25
19
221
0.85
0.23
5.2
3.6
45.29
47.75
%
0.15
19
216
83
780
1.08
0.22
1.5
1.3
3.16
11.43
u/ml
1.99
29
302
27
239
1.14
0.21
4.3
3.3
3.01
1.92
mmol/l
0.70
17
183
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
11
89
1.24
0.21
2.4
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
51
1.18
0.19
1.0
1.2
—
—
—
0
0
6
52
1.16
0.19
6.8
4.1
—
—
—
0
0
16
137
1.17
0.19
2.7
1.6
0.23
0.23
g/l
0.05
16
131
13
109
1.20
0.18
1.2
1.1
—
5.20
—
0
15
18
157
1.15
0.17
1.7
3.0
—
—
—
0
0
15
129
1.17
0.17
1.6
1.4
112.89
246.55
miu/ml
—
9
64
8
73
1.10
0.15
1.0
1.1
—
15.15
—
0
22
12
140
0.85
0.15
1.8
1.8
39.00
39.72
nmol/l
0.06
12
133
12
102
1.18
0.15
1.3
1.6
—
—
—
0
0
14
121
1.16
0.15
1.4
1.2
—
—
—
0
0
7
88
0.79
0.14
1.0
1.2
16.72
18.64
u/l
—
7
76
29
267
1.09
0.13
1.3
1.4
—
46.44
—
0
23
16
142
1.13
0.13
2.6
1.6
1.19
1.20
g/l
0.06
16
136
33
310
1.07
0.10
1.7
1.8
3.50
3.54
mmol/l
0.06
24
234
5
63
0.79
0.08
2.0
1.3
—
—
—
0
0
5
63
0.79
0.08
1.6
1.4
5.52
7.23
mmol/l
—
5
53
5
64
0.78
0.08
1.2
1.1
—
2.08
—
0
12
5
64
0.78
0.08
2.0
1.4
—
—
—
0
0
5
64
0.78
0.08
2.0
1.4
—
—
—
0
0
11
123
0.89
0.08
1.0
1.3
—
—
—
0
0
15
137
1.10
0.07
1.6
2.3
80.20
91.58
%
0.95
15
132
8
92
0.87
0.07
1.0
1.6
1.03
0.84
nmol/l
—
8
79
54
524
1.03
0.05
4.8
5.0
30.69
31.86
%
0.34
35
345
251
2530
0.98
0.05
3.5
3.0
—
—
—
0
0
19
201
0.94
0.04
4.4
3.2
25.34
25.10
mmol/l
0.13
19
195
40
413
0.97
0.04
2.7
2.1
—
—
—
0
0
41
423
0.97
0.04
2.0
2.0
3.35
3.47
ratio
0.22
32
346
123
1247
0.98
0.04
3.5
3.2
1.02
0.07
estimate
0.46
50
379
146
1448
1.01
0.02
4.3
4.2
4.67
8.76
mg/mmol
1.31
85
890
75
759
0.99
0.01
3.0
3.2
0.63
0.74
ug/l
1.26
43
490
37
378
0.98
0.01
2.4
1.9
—
—
—
0
0
10
105
0.95
0.00
1.4
2.5
9.44
90.53
ug/min
—
5
55
14
138
1.01
0.00
1.5
1.3
—
—
—
0
0
14
138
1.01
0.00
2.2
1.6
—
—
—
0
0
127
1273
1.00
0.00
4.8
5.3
1.79
2.34
ug/l
0.81
111
1157
102
1024
1.00
0.00
4.0
4.4
22.35
21.79
%
0.16
53
478
5
51
0.98
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
-0.00
5.0
3.9
30.75
371.29
u/ml
—
8
82
0
7
0.00
-0.00
0.0
9.1
—
10.49
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
99
990
1.00
-0.00
4.5
3.9
1.02
1.02
kg/l
0.05
69
667
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
92
0.98
-0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.16
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
12.18
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_TONSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TONSIL | 1.132 [0.94, 1.37] | 0.203 |
| Birth year | 0.995 [0.99, 1.0] | 0.236 |
During the follow-up period (1.1.1998 — 31.12.2019), 175 out of 1274 females with CD2_BENIGN_TONSIL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_TONSIL | 1.917 [1.5, 2.46] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 943 males with CD2_BENIGN_TONSIL died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_TONSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.13% | 0.355% |
| 5 | 0.709% | 2.208% |
| 10 | 1.835% | 5.227% |
| 15 | 3.23% | 10.463% |
| 20 | 5.62% | 18.211% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_TONSIL – Benign neoplasm: Tonsil
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data