Corticotropin deficiency

E4_CORTICOTROPIN_DEFICIENCY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E23.03
  • Cause of death: ICD-10 E23.03

2 out of 7 registries used, show all original rules.

345

4. Check minimum number of events

None

345

5. Include endpoints

None

345

6. Filter based on genotype QC (FinnGen only)

317

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 317 200 117
Unadjusted period prevalence (%) 0.06 0.07 0.05
Median age at first event (years) 58.63 56.42 62.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
324
Matched controls
3240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E23.03
ICD-10 Finland
Lack of ACTH
+∞
307.7
324
*
H02AB09
ATC
hydrocortisone; systemic
1125.8
307.7
303
41
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
60.0
96.8
55
11
101
Kela drug reimbursment
Anterior pituitary hypofunction
150.3
86.0
88
8
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
255.6
79.1
78
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
16.9
78.4
71
53
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
127.0
66.9
70
7
E23.00
ICD-10 Finland
Panhypopituitarism
194.6
62.4
63
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
122.3
57.0
60
6
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
11.7
56.7
64
67
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
315.5
53.9
53
*
H03AA01
ATC
levothyroxine sodium; systemic
5.5
51.8
164
508
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
7.8
46.8
75
121
J45.9
ICD-10 Finland
Asthma, unspecified
4.4
35.2
126
410
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
10.7
34.9
40
42
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
32.4
224
1135
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.6
30.0
89
248
N02AA05
ATC
oxycodone; systemic
4.1
29.3
108
353
R03AK08
ATC
formoterol and beclometasone; inhalant
7.4
28.9
45
69
E23.05
ICD-10 Finland
Lack of TSH
306.6
28.2
28
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.6
28.2
148
612
H02AB06
ATC
prednisolone; systemic
3.7
27.8
218
1156
E27.2
ICD-10 Finland
Addisonian crisis
+∞
27.5
26
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.8
26.7
71
180
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
65.8
26.5
30
5
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
26.4
25
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.4
26.1
165
758
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.7
25.5
108
384
R03BB04
ATC
tiotropium bromide; inhalant
4.9
25.5
65
159
J45
ICD-10 Finland
Asthma
4.5
25.2
72
193
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.5
24.0
110
410
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
23.8
81
247
N03AE01
ATC
clonazepam; systemic
6.0
23.5
45
85
R11
ICD-10 Finland
Nausea and vomiting
4.5
23.0
65
172
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.5
22.9
64
168
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
22.3
114
452
R53
ICD-10 Finland
Malaise and fatigue
3.2
22.2
139
622
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.8
22.0
84
276
H02AA02
ATC
fludrocortisone; oral
86.2
22.0
24
*
UJF32
NOMESCO Finland
Coloscopy
3.2
21.9
125
529
AA1AD
NOMESCO Finland
CT of head and brain
3.1
21.3
136
613
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.2
20.8
63
175
M05BA04
ATC
alendronic acid; oral
4.7
20.7
53
129
N06AX21
ATC
duloxetine; oral
3.8
20.7
77
248
N03AX16
ATC
[U] pregabalin
3.1
20.1
116
491
M05BX04
ATC
denosumab; parenteral
5.1
19.6
44
96
R52.2
ICD-10 Finland
Other chronic pain
6.0
19.3
36
66
J01MA12
ATC
levofloxacin; systemic
3.3
19.0
92
349
WZC00
NOMESCO Finland
Treatment plan or consultation
2.8
19.0
165
866
H02AB04
ATC
methylprednisolone; systemic
3.5
18.9
78
268
L04AX01
ATC
azathioprine; systemic
6.5
18.6
32
54
C10AC01
ATC
colestyramine; oral
8.4
18.5
25
32
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.8
18.5
64
195
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.4
18.5
81
289
105
Kela drug reimbursment
Adrenal cortical hypofunction
190.0
17.7
18
*
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
7.9
17.6
25
34
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.0
17.1
55
159
Z01.8
ICD-10 Finland
Other specified special examinations
2.9
17.1
107
468
R96
ICPC
Asthma
3.8
17.0
60
185
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
17.0
84
321
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
16.9
82
310
E23.08
ICD-10 Finland
Hypopituitarism
+∞
16.8
16
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.0
16.6
53
152
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.3
16.6
75
271
R03BA08
ATC
ciclesonide; inhalant
3.8
16.5
57
173
R03DC03
ATC
montelukast; oral
3.0
16.5
90
364
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.4
16.3
34
69
R51.80
ICD-10 Finland
Headache
3.0
16.3
94
392
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
6.8
16.1
26
41
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.2
16.0
46
122
WX892
NOMESCO Finland
Monitored bed care
4.2
15.8
46
123
N06AA09
ATC
amitriptyline; systemic
3.7
15.8
56
173
C03CA01
ATC
furosemide; systemic
2.7
15.6
117
558
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.8
15.6
111
516
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.6
15.6
58
185
SPAT1254
SPAT
Administration of medicine
3.3
15.6
69
246
J45.8
ICD-10 Finland
Mixed asthma
6.3
15.5
27
46
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.3
15.4
67
236
A02BC02
ATC
pantoprazole; systemic
3.0
15.4
257
1806
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.0
15.4
28
50
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
5.0
15.3
35
77
R03DA04
ATC
theophylline; systemic, rectal
5.2
15.3
33
69
N03AX12
ATC
[U] gabapentin; oral
2.9
15.2
88
366
N05AH04
ATC
quetiapine; oral
2.8
14.9
93
402
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.2
14.7
26
45
E23.3
ICD-10 Finland
Hypothalamic dysfunction, not elsewhere classified
+∞
14.7
14
*
S18
ICPC
Laceration/cut
2.5
14.5
192
1189
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
14.5
68
250
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
14.5
111
532
R06.0
ICD-10 Finland
Dyspnoea
2.6
14.5
122
613
R03AC13
ATC
formoterol; inhalant
4.7
14.4
35
81
J45.1
ICD-10 Finland
Nonallergic asthma
3.9
14.4
46
132
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
14.3
75
294
D64.9
ICD-10 Finland
Anaemia, unspecified
3.6
14.2
53
169
N05BA04
ATC
oxazepam; oral
2.6
14.0
119
598
SPAT1229
SPAT
Assessment of need for aid
4.3
14.0
39
101
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
55.9
13.9
16
*
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
55.9
13.9
16
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.9
13.8
22
34
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.4
13.8
55
183
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.8
13.7
45
131
N05CD07
ATC
temazepam; oral
3.4
13.6
54
179
L01BA01
ATC
methotrexate; systemic
5.9
13.6
25
45
TPH07
NOMESCO Finland
Cathetrisation of artery
3.4
13.5
55
185
SPAT1262
SPAT
Handing over of treatment supplies
2.9
13.5
78
322
M81.9
ICD-10 Finland
Osteoporosis, unspecified
5.1
13.3
29
61
A03FA01
ATC
metoclopramide; systemic, rectal
2.6
13.1
103
497
N06AX11
ATC
mirtazapine; oral
2.4
13.1
144
811
H01AC01
ATC
somatropin; parenteral
52.2
13.0
15
*
N02AX02
ATC
tramadol; systemic, rectal
2.4
12.9
170
1033
R50.9
ICD-10 Finland
Fever, unspecified
2.8
12.8
76
318
WZC30
NOMESCO Finland
Teaching
2.8
12.8
80
344
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.3
12.6
26
52
E27.9
ICD-10 Finland
Disorder of adrenal gland, unspecified
+∞
12.6
12
*
R03BA05
ATC
fluticasone; inhalant
2.6
12.6
88
400
N06AX16
ATC
venlafaxine; oral
2.8
12.5
76
321
E23.2
ICD-10 Finland
Diabetes insipidus
135.0
12.5
13
*
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
15.1
12.4
20
14
R02
ICPC
Shortness of breath/dyspnoea
3.0
12.4
64
248
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
12.2
148
862
N05BA01
ATC
diazepam; systemic, rectal
2.9
12.1
64
251
H02AB07
ATC
prednisone; oral
2.9
12.1
64
251
E22.1
ICD-10 Finland
Hyperprolactinaemia
48.6
12.0
14
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.7
11.8
40
119
A06AC01
ATC
ispaghula (psylla seeds); oral
2.4
11.7
111
579
A12BA01
ATC
potassium chloride; oral
5.6
11.7
23
44
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.2
11.7
50
173
E87.6
ICD-10 Finland
Hypokalaemia
4.8
11.7
27
60
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.1
11.6
25
52
R03AC12
ATC
salmeterol; inhalant
4.5
11.5
29
69
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
11.5
105
538
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
124.2
11.5
12
*
102
Kela drug reimbursment
Diabetes insipidus
124.2
11.5
12
*
L28
ICPC
Limited function/disability (L)
2.6
11.4
81
369
A04AA01
ATC
ondansetron; systemic, rectal
3.4
11.4
45
148
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.6
11.4
84
390
NF1AA
NOMESCO Finland
Hip X-ray examination
3.4
11.4
44
143
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.3
11.3
46
154
J01MA02
ATC
ciprofloxacin; systemic
2.2
11.3
146
867
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.9
11.3
62
248
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
9.1
11.2
23
27
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.0
11.2
55
206
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
11.1
68
287
A02BC01
ATC
omeprazole; systemic
2.4
11.1
108
568
J01FF01
ATC
clindamycin; systemic
2.3
11.1
111
591
E0000UV, ,
ATC
2.2
11.1
163
1017
SPAT1301
SPAT
No procedures
2.3
11.1
121
669
J46
ICD-10 Finland
Status asthmaticus
5.7
11.0
21
39
SPAT1153
SPAT
Removal of sutures
2.3
11.0
126
710
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.8
11.0
61
245
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.5
10.8
79
364
N05CF01
ATC
zopiclone; oral
2.2
10.7
127
725
R55
ICD-10 Finland
Syncope and collapse
3.0
10.7
52
194
ZX120
NOMESCO Finland
Intravenous
3.1
10.7
48
171
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.1
10.7
23
48
A07EC01
ATC
sulfasalazine; oral, rectal
3.5
10.6
38
117
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.8
10.6
60
243
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.9
10.5
32
88
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
113.5
10.5
11
*
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.1
10.5
30
79
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
10.5
56
220
A01
ICPC
Pain general/multiple sites
2.9
10.5
53
202
SPAT1263
SPAT
Sampling
2.2
10.5
158
990
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.7
10.5
25
57
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.6
10.5
70
309
WX402
NOMESCO Finland
General anaesthesia
2.4
10.4
96
491
N03AX11
ATC
topiramate; oral
5.0
10.4
23
49
A02BC05
ATC
esomeprazole; systemic
2.2
10.4
156
975
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.9
10.4
54
209
M54.4
ICD-10 Finland
Lumbago with sciatica
2.4
10.4
85
413
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.9
10.3
52
198
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.6
10.2
68
299
A04
ICPC
Weakness/tiredness general
2.6
10.2
69
306
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
10.2
160
1015
E000001, ,
ATC
2.5
10.2
81
388
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
10.2
47
170
L95
ICPC
Osteoporosis
4.4
10.1
26
63
WX002
NOMESCO Finland
Sedation and analgesia
2.5
10.0
79
376
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.1
10.0
45
160
C03DA01
ATC
spironolactone; oral
2.8
10.0
55
219
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
10.0
81
391
R03BA01
ATC
beclometasone; inhalant
2.6
10.0
65
283
M47.9
ICD-10 Finland
Spondylosis, unspecified
5.2
9.9
21
43
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.9
9.9
52
202
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
9.8
49
185
H04.10
ICD-10 Finland
Dry eye syndrome
2.7
9.8
60
253
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.7
9.7
23
52
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.3
9.7
20
40
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.8
9.7
55
223
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.7
9.6
31
89
R33
ICD-10 Finland
Retention of urine
3.4
9.6
37
120
A02BA02
ATC
ranitidine; systemic
2.4
9.6
76
363
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.5
9.6
24
57
H05AA02
ATC
teriparatide; parenteral
31.0
9.5
12
*
E23.06
ICD-10 Finland
Empty sella
102.9
9.5
10
*
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
102.9
9.5
10
*
I95.1
ICD-10 Finland
Orthostatic hypotension
4.9
9.4
21
45
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
+∞
9.4
9
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.1
9.4
148
933
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.7
9.3
31
91
E86
ICD-10 Finland
Volume depletion
8.1
9.3
20
26
C09CA06
ATC
candesartan; oral
2.2
9.2
99
537
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.2
9.1
38
129
C07AB07
ATC
bisoprolol; oral
2.0
9.0
171
1148
318
Kela drug reimbursment
Teriparatide
24.8
9.0
12
5
J37.0
ICD-10 Finland
Chronic laryngitis
4.7
9.0
21
47
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
9.0
194
1364
SPAT1260
SPAT
Consultation of another employee
2.4
8.9
72
345
K59.09
ICD-10 Finland
Constipation, unspecified
3.4
8.9
33
104
R03AC03
ATC
terbutaline; inhalant
2.6
8.8
59
260
S20.2
ICD-10 Finland
Contusion of thorax
3.7
8.7
28
80
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.5
8.7
31
95
L86
ICPC
Back syndrome with radiating pain
3.3
8.7
35
116
301
Kela drug reimbursment
Growth hormone
51.4
8.7
10
*
M79.7
ICD-10 Finland
Fibromyalgia
4.3
8.7
23
57
SPAT1310
SPAT
Counselling related to known health issue
2.1
8.7
122
732
R03AK07
ATC
formoterol and budesonide; inhalant
2.2
8.6
88
466
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.8
8.6
45
174
A06AD11
ATC
lactulose; oral
2.6
8.5
55
237
R03BA02
ATC
budesonide; inhalant
2.3
8.5
79
402
A28
ICPC
Limited function/disability NOS
2.4
8.5
65
304
UJG02
NOMESCO Finland
Proctoscopy
8.2
8.5
18
23
A46
ICD-10 Finland
Erysipelas
2.5
8.5
59
264
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
92.4
8.5
9
*
R01AD09
ATC
mometasone; nasal
2.0
8.4
168
1139
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.3
8.4
33
108
C07AA05
ATC
propranolol; systemic
2.2
8.4
88
471
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
+∞
8.4
8
*
N03AX09
ATC
lamotrigine; oral
3.5
8.3
30
93
WZC00, ,
SPAT
2.4
8.3
63
294
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
8.2
65
308
A02BX02
ATC
sucralfate; oral
4.7
8.2
19
42
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
8.2
107
622
XQ800
NOMESCO Finland
Prick test
3.1
8.2
36
126
A10AB05
ATC
insulin aspart; parenteral
2.9
8.2
40
149
M70.6
ICD-10 Finland
Trochanteric bursitis
2.4
8.2
64
302
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.8
8.2
44
173
S97
ICPC
Chronic ulcer skin
3.2
8.2
33
110
J01DC02
ATC
cefuroxime; systemic
3.6
8.1
28
84
N05AA02
ATC
levomepromazine; systemic
4.0
8.1
23
60
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.3
8.1
32
105
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.0
8.1
119
722
N02BF02
ATC
pregabalin; oral
3.0
8.1
37
133
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
4.5
8.1
20
47
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
8.0
30
95
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.0
8.0
38
139
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
8.0
114
683
NH3EA
NOMESCO Finland
Feet X-ray examination with load
8.1
8.0
17
22
ZXD05
NOMESCO Finland
Urgent procedure
2.0
8.0
113
676
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.8
8.0
18
39
N06AB10
ATC
escitalopram; oral
2.2
8.0
87
472
XX3DW
NOMESCO Finland
Time consuming IT work
2.6
8.0
51
219
SPAT1255
SPAT
Intravenous administration of medicine
3.3
7.9
30
96
M13.9
ICD-10 Finland
Arthritis, unspecified
3.0
7.9
36
129
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
11.2
7.9
14
13
SPAT1325
SPAT
Vaccination
2.0
7.8
118
721
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.7
7.8
45
183
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.7
7.8
44
177
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
46.1
7.7
9
*
GD1AD
NOMESCO Finland
Thorax CT examination
3.2
7.7
32
108
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.4
7.7
29
92
N06AX12
ATC
bupropion; oral
2.9
7.7
38
142
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.8
7.7
42
166
ZYC01
NOMESCO Finland
Remote contact by phone
3.1
7.7
33
114
WVA20, ,
SPAT
4.0
7.7
22
58
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
12.3
7.6
13
11
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.0
7.6
34
120
N91.1
ICD-10 Finland
Secondary amenorrhoea
9.2
7.6
15
17
N04BC06
ATC
cabergoline; oral
25.7
7.6
10
*
ZXC86
NOMESCO Finland
Use of endoscopic device
25.7
7.6
10
*
JN4AD
NOMESCO Finland
Body CT examination
2.6
7.6
49
211
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.7
7.6
24
68
R60.0
ICD-10 Finland
Localized oedema
2.5
7.6
54
244
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.6
7.6
25
73
S01
ICPC
Pain/tenderness of skin
3.6
7.6
25
73
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.9
7.5
22
59
R03AC02
ATC
salbutamol; inhalant
1.9
7.5
199
1464
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
13.8
7.4
12
9
SPAT1240
SPAT
Therapeutic discussion
2.5
7.4
48
207
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.3
7.4
19
46
SPAT1312
SPAT
General health counselling
2.0
7.4
115
709
T90
ICPC
Diabetes non-insulin dependent
2.1
7.3
88
493
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
7.3
50
221
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.1
7.3
90
509
M54.1
ICD-10 Finland
Radiculopathy
3.9
7.3
22
60
E23.6
ICD-10 Finland
Other disorders of pituitary gland
+∞
7.3
7
*
E23
ICD-10 Finland
Hypofunction and other disorders of pituitary gland
+∞
7.3
7
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.1
7.3
32
112
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
7.3
79
426
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
16.2
7.3
11
7
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.1
7.3
20
51
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.5
7.3
25
75
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.0
7.3
33
118
M81.4
ICD-10 Finland
Drug-induced osteoporosis
20.6
7.2
10
5
XG410
NOMESCO Finland
Flow-volume spirometry
3.8
7.2
22
61
M54.5
ICD-10 Finland
Low back pain
1.9
7.1
135
885
L04AX03
ATC
methotrexate; systemic
2.6
7.1
43
179
R06AX13
ATC
loratadine; oral
2.2
7.1
64
320
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
7.1
42
173
C07AB02
ATC
metoprolol; systemic
2.2
7.1
69
356
OAB50, ,
SPAT
2.8
7.1
36
137
J02AC01
ATC
fluconazole; systemic
1.9
7.1
144
966
S06
ICPC
Rash localized
3.3
7.0
27
87
R06AE07
ATC
cetirizine; oral
1.9
7.0
156
1077
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.6
7.0
43
181
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
7.0
157
1087
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.0
6.9
105
638
M01AH01
ATC
celecoxib; oral
2.2
6.9
67
345
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.0
6.9
20
53
R42
ICD-10 Finland
Dizziness and giddiness
2.0
6.9
87
496
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
9.6
6.8
13
14
XCK00
NOMESCO Finland
Perimetry
3.2
6.8
28
94
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
6.8
107
658
N03AG01
ATC
valproic acid; systemic, rectal
3.0
6.8
31
111
J01DB01
ATC
cefalexin; oral
2.3
6.8
278
2338
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.7
6.7
37
147
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.1
6.7
17
29
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
6.1
6.7
17
29
M79.6
ICD-10 Finland
Pain in limb
1.8
6.7
160
1125
L03
ICPC
Low back symptom/complaint
1.9
6.6
107
663
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.1
6.6
28
96
I95.9
ICD-10 Finland
Hypotension, unspecified
7.1
6.6
15
22
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.9
6.6
32
119
WVA30, ,
SPAT
3.0
6.6
29
102
WX725
NOMESCO Finland
Noninvasive ventilation
3.1
6.6
27
91
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.7
6.5
36
143
SPAT1216
SPAT
Assessment of functional ability
2.2
6.5
57
281
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.9
6.5
31
114
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
6.5
25
81
N06AB05
ATC
paroxetine; oral
3.0
6.4
29
103
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
71.2
6.4
7
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.2
6.4
17
42
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
14.7
6.4
10
7
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.3
6.4
24
76
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
6.4
144
988
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.7
6.4
20
56
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
6.4
134
900
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.2
6.4
26
87
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
6.2
6.4
16
27
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
6.4
74
408
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
6.4
102
629
N04BC05
ATC
pramipexole; oral
2.7
6.4
35
139
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.0
6.3
18
47
A06AH03
ATC
naloxegol; oral
9.5
6.3
12
13
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
9.5
6.3
12
13
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.9
6.3
30
110
N06AB04
ATC
citalopram; systemic
2.0
6.3
78
440
A07AA02
ATC
nystatin; oral
3.0
6.3
28
99
297, ,
Kela drug reimbursment
+∞
6.3
6
*
R03DX09
ATC
mepolizumab; parenteral
+∞
6.3
6
*
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
27.2
6.3
8
*
R63.4
ICD-10 Finland
Abnormal weight loss
3.6
6.3
21
62
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.3
6.3
52
251
C01CA24
ATC
epinephrine; parenteral
2.7
6.2
34
135
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.3
6.1
23
73
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.4
6.1
22
68
M89.0
ICD-10 Finland
Algoneurodystrophy
12.8
6.1
10
8
P01BA02
ATC
hydroxychloroquine; oral
2.6
6.1
36
148
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
8.9
6.1
12
14
TQW99
NOMESCO Finland
Other minor procedure on skin
3.1
6.1
25
84
TAB00
NOMESCO Finland
Lumbar puncture
3.1
6.1
25
84
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.6
6.1
35
142
UDC00
NOMESCO Finland
Ear microscopy
2.7
6.1
34
136
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.4
6.1
43
193
UKC02
NOMESCO Finland
Cystoscopy
2.2
6.1
56
282
JG1JB
NOMESCO Finland
Defekography with X-ray
10.3
6.1
11
11
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
10.3
6.1
11
11
A03
ICPC
Fever
2.1
6.1
69
377
A41.9
ICD-10 Finland
Sepsis, unspecified
4.0
6.1
17
44
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.0
6.1
17
44
J01FA15
ATC
telithromycin; oral
2.4
6.1
42
187

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
268
321
43.52
246.26
9.1
2.1
197.52
382.18
nmol/l
27.21
255
300
110
94
17.20
114.48
2.0
1.3
12.87
10.99
u/l
0.38
95
74
120
194
9.24
77.28
5.2
3.5
4.32
4.47
pmol/l
0.69
115
174
51
27
22.23
66.23
2.9
1.4
338.36
243.48
mu/l
1.54
44
21
52
38
16.11
57.51
2.3
1.1
278.00
272.67
mosm/kgh2o
0.34
42
27
261
1294
6.23
43.79
15.1
7.0
1.21
1.21
mmol/l
1.06
251
1206
274
1426
6.97
43.06
15.0
7.8
1.21
1.21
mmol/l
0.40
237
1249
149
497
4.70
41.27
4.8
3.8
0.79
0.82
mmol/l
1.57
141
474
49
55
10.32
40.91
1.9
2.1
0.72
0.86
g/l
0.20
28
48
147
497
4.58
39.75
3.3
2.5
12.49
13.50
umol/l
0.90
136
470
246
1239
5.09
38.25
7.5
4.9
34.58
36.15
g/l
4.47
239
1179
123
378
4.63
37.35
5.4
6.7
1.03
1.05
mmol/l
0.33
117
346
182
749
4.26
37.05
3.2
2.3
2.88
2.88
mg/l
0.00
168
654
138
468
4.39
36.69
3.1
2.5
2.32
2.33
g/l
0.06
128
434
182
762
4.17
35.87
7.7
4.4
—
—
—
0
0
37
34
12.16
35.28
2.0
1.4
0.47
0.32
g/l
0.75
18
28
37
34
12.16
35.28
2.0
1.4
2.66
2.43
g/l
0.24
17
27
37
34
12.16
35.28
2.0
1.4
5.96
7.06
g/l
0.45
18
28
200
906
4.16
34.93
6.7
4.3
7.40
7.40
ph
0.52
158
644
283
1655
6.61
34.79
12.7
5.2
6.54
6.61
mmol/l
0.24
277
1567
82
191
5.41
34.68
2.2
1.3
26.39
25.80
iu/l
0.05
75
160
37
35
11.81
34.61
2.0
1.3
—
—
—
0
0
129
432
4.30
34.58
3.3
2.5
22.99
23.11
%
0.03
120
409
91
253
4.61
30.82
3.2
2.6
10.02
10.58
g/l
0.57
77
235
94
273
4.44
30.03
5.1
5.3
1.20
0.93
%
0.37
50
89
199
965
3.75
29.96
11.0
6.5
—
—
—
0
0
102
318
4.22
29.59
13.1
9.1
7.41
7.41
ph
0.01
69
186
101
315
4.21
29.25
11.8
9.1
1.24
0.86
mmol/l
0.49
87
266
189
917
3.55
27.79
6.7
2.5
52.91
62.16
u/l
1.02
182
861
184
878
3.54
27.79
3.4
2.2
261.55
181.45
u/l
0.43
176
838
263
1580
4.53
27.77
12.0
7.1
0.19
0.19
e9/l
0.06
238
1392
141
570
3.61
27.71
4.3
2.9
443.99
527.92
mosm/kgh2o
4.09
130
498
83
232
4.47
27.69
4.2
2.4
12.52
13.52
nmol/l
0.44
72
218
42
63
7.51
27.47
1.7
1.5
0.35
0.30
nmol/l
0.21
25
48
235
1321
3.84
27.09
4.8
2.6
80.19
75.65
nmol/l
1.92
222
1201
87
257
4.26
26.92
5.0
5.5
0.07
0.15
%
0.68
43
73
256
1527
4.22
26.87
11.7
6.6
0.64
0.57
e9/l
5.49
236
1316
243
1402
3.93
26.77
11.4
6.7
8.73
8.69
%
0.07
237
1324
256
1532
4.20
26.62
11.7
6.6
0.04
0.04
e9/l
0.86
237
1319
87
260
4.21
26.47
5.1
5.2
0.51
0.58
%
0.20
44
84
242
1402
3.87
26.27
11.3
6.6
2.56
2.84
%
1.24
236
1320
241
1399
3.82
25.93
11.4
6.6
0.67
0.68
%
0.10
235
1312
244
1433
3.85
25.66
11.3
6.6
28.23
27.75
%
0.24
239
1361
256
1559
4.06
25.29
11.9
6.7
2.39
1.96
e9/l
0.48
236
1387
227
1289
3.54
24.84
17.3
11.5
1.15
1.19
inr
0.71
197
1054
65
163
4.74
24.71
10.2
3.8
—
—
—
0
0
267
1696
4.26
24.21
15.6
10.7
5.07
4.04
e9/l
1.10
245
1476
81
251
3.97
23.20
2.9
2.8
0.21
0.22
g/l
0.20
74
239
252
1578
3.69
22.49
12.5
6.8
11.08
11.01
umol/l
0.02
244
1512
67
190
4.18
21.59
6.6
4.2
7.43
7.42
ph
0.65
60
158
310
2276
9.38
21.59
12.1
4.5
15.14
14.71
pmol/l
2.17
301
2089
83
275
3.71
21.45
5.4
5.7
0.00
0.20
%
0.98
39
75
34
55
6.79
20.63
2.5
1.5
43.23
24.75
u/l
1.39
28
46
103
403
3.28
20.40
11.9
7.8
103.18
104.10
mmol/l
0.93
103
403
233
1448
3.17
19.86
4.9
3.1
97.84
107.88
ug/l
0.54
223
1367
84
296
3.48
19.62
7.1
4.6
7.38
7.38
ph
0.61
51
166
105
428
3.15
19.27
3.1
2.0
—
—
—
0
0
194
1106
2.88
19.11
7.7
3.7
27.11
84.76
ng/l
0.55
158
747
109
458
3.08
18.94
1.7
1.4
378.18
542.86
titre
0.61
22
112
81
285
3.46
18.91
7.1
4.6
2.48
1.78
mmol/l
1.00
72
245
75
252
3.57
18.79
2.3
3.5
73.73
70.72
e9/l
0.28
54
192
90
341
3.27
18.62
2.5
3.4
1.86
1.82
%
0.16
76
312
25
32
8.38
18.54
1.2
1.3
—
—
nmol/l
—
0
0
158
819
2.81
18.53
2.1
1.7
19.66
21.13
nmol/l
0.58
144
690
32
55
6.35
18.28
4.9
2.6
—
—
—
0
0
66
213
3.64
17.50
1.4
1.2
98.27
170.32
u/ml
1.01
34
96
24
32
8.02
17.19
1.5
1.3
1.16
1.03
u/ml
0.05
19
18
93
382
3.01
16.55
3.6
3.3
4.86
4.88
e9/l
0.01
78
340
121
575
2.76
16.39
1.9
1.7
64706322.49
23732681.13
pmol/l
0.26
102
493
176
1007
2.64
16.38
4.3
3.4
2.34
2.35
mmol/l
0.55
164
922
28
47
6.43
16.34
3.2
3.5
4.74
4.89
e9/l
0.10
28
47
23
32
7.66
15.88
2.3
4.1
—
—
—
0
0
41
101
4.50
15.69
4.5
2.6
24.91
24.77
mmol/l
0.08
41
101
38
91
4.60
15.05
1.8
1.4
283.08
307.99
ug/g
0.34
24
50
29
56
5.59
14.67
5.9
2.5
2.90
2.71
mmol/l
0.11
22
38
63
220
3.31
14.64
2.0
1.3
123.79
247.06
u/ml
0.82
57
205
25
43
6.22
14.22
1.2
1.3
0.56
0.53
nmol/l
0.19
25
38
31
66
5.09
14.09
4.3
2.9
34.69
34.75
umol/l
0.00
26
59
133
710
2.48
13.73
9.7
5.2
—
—
—
0
0
151
855
2.43
13.68
4.5
3.4
1070.44
1070.92
ng/l
0.00
134
733
206
1347
2.45
13.39
4.3
2.7
—
—
estimate
—
0
0
194
1245
2.39
13.01
2.8
2.1
104.46
95.76
pmol/l
1.44
115
643
98
467
2.57
12.74
2.1
1.6
1217.14
1188.06
nmol/l
0.11
79
357
149
868
2.33
12.32
5.6
2.9
—
—
—
0
0
54
191
3.19
12.19
1.5
2.9
—
—
—
0
0
27
58
4.99
12.12
2.0
1.5
—
—
—
0
0
29
67
4.66
11.96
3.8
3.3
56.31
61.26
%
1.04
29
67
62
243
2.92
11.70
2.1
3.3
65.49
67.11
g/l
0.99
56
233
78
345
2.66
11.70
2.4
1.6
—
—
—
0
0
62
249
2.84
11.16
9.7
10.8
—
—
—
0
0
314
2660
6.85
10.87
12.9
5.5
1.71
1.88
mu/l
1.24
304
2468
22
44
5.29
10.68
1.1
1.0
6.98
23.30
iu/ml
—
8
10
152
936
2.18
10.54
4.0
2.3
—
—
—
0
0
145
882
2.17
10.32
7.4
3.8
0.00
0.00
estimate
-0.00
74
312
133
784
2.18
10.24
1.5
1.3
0.62
1.58
u/ml
2.08
46
210
220
1592
2.19
9.76
6.9
3.7
0.00
5.67
estimate
0.50
77
331
57
236
2.72
9.62
6.5
3.7
—
—
—
0
0
122
711
2.15
9.53
1.8
1.4
2.37
2.28
g/l
0.23
92
437
29
80
3.88
9.50
8.7
3.4
8.62
8.33
kpa
0.35
29
80
16
13
12.87
9.46
2.4
1.4
220.75
55.69
nmol/24h
1.73
16
13
44
160
3.02
9.41
1.4
1.3
—
—
—
0
0
180
1219
2.07
9.37
6.9
3.6
0.00
0.01
estimate
0.74
73
280
55
229
2.69
9.17
3.4
3.7
90.25
78.26
ng/l
0.35
47
205
33
103
3.45
9.04
1.4
1.3
—
—
—
0
0
118
692
2.11
8.97
2.0
1.8
0.76
1.29
mg/l
2.12
89
557
39
136
3.12
8.95
8.5
4.6
—
—
—
0
0
218
1608
2.09
8.71
7.0
3.7
0.00
0.02
estimate
0.79
75
306
76
377
2.33
8.71
2.1
1.4
—
—
—
0
0
24
62
4.10
8.58
1.3
1.8
—
—
—
0
0
141
896
2.02
8.52
6.0
3.2
0.00
0.00
estimate
0.50
71
272
213
1580
2.02
8.10
7.0
3.7
0.00
0.00
estimate
-0.00
75
328
180
1263
1.96
8.01
5.5
3.3
6.30
6.20
ph
0.69
108
732
45
181
2.73
7.99
7.7
5.0
25.24
24.31
mmol/l
1.35
45
181
40
151
2.88
7.99
1.8
1.7
9.34
8.79
iu/ml
—
8
37
41
159
2.81
7.80
8.1
3.5
0.69
0.62
%
0.63
41
159
146
981
1.89
7.16
3.4
3.3
6.69
7.74
mmol/l
2.18
125
839
109
671
1.94
6.93
4.6
2.7
6.82
5.49
e6/l
0.49
102
611
14
17
8.55
6.90
1.9
1.4
—
—
—
0
0
305
2682
3.34
6.73
9.3
6.2
40.95
39.04
mmol/mol
2.29
295
2547
127
833
1.86
6.59
5.7
3.2
0.23
0.35
e6/l
0.96
108
607
18
46
4.08
6.53
3.6
3.0
—
—
—
0
0
73
399
2.07
6.44
3.1
2.5
122.66
105.88
ug/g
0.18
62
317
67
355
2.12
6.41
1.4
1.3
—
—
—
0
0
307
2727
3.40
6.30
7.3
5.0
5.84
5.90
mmol/l
0.28
299
2534
6
0
+∞
6.27
1.3
0.0
1.58
—
nmol/l
—
6
0
6
0
+∞
6.27
1.5
0.0
2.76
—
mu/l
—
6
0
21
62
3.55
6.25
3.9
3.1
9.10
8.54
pmol/l
0.08
21
62
27
94
3.04
6.21
1.4
4.6
26.86
38.44
mg/l
1.38
20
82
54
266
2.24
6.19
1.4
1.4
—
—
—
0
0
313
2819
4.25
6.15
45.2
15.5
19.70
22.44
mg/l
1.36
296
2299
19
54
3.68
5.97
1.2
1.1
—
—
—
0
0
28
102
2.91
5.96
1.2
1.3
—
—
—
0
0
12
15
8.26
5.89
1.2
2.2
—
—
—
0
0
139
963
1.78
5.87
5.9
3.3
97.89
133.82
e6/l
0.15
120
735
91
556
1.89
5.78
1.8
2.0
—
—
—
0
0
25
87
3.03
5.76
2.3
2.1
184.12
4.71
iu/l
0.47
17
35
181
1359
1.75
5.72
28.1
11.7
0.27
0.00
e9/l
0.49
154
1109
21
66
3.33
5.70
1.4
1.4
—
—
—
0
0
26
94
2.92
5.61
1.4
4.6
24.10
30.13
mg/l
0.61
19
80
149
1065
1.74
5.56
6.3
3.4
31.67
31.70
u/l
0.00
143
1017
131
905
1.75
5.50
3.6
3.5
29.56
45.52
mg/l
0.96
77
589
18
54
3.47
5.24
3.0
1.7
1.21
0.83
nmol/l
0.73
12
46
244
2024
1.83
5.21
6.8
3.4
66.41
44.10
u/l
1.87
234
1922
36
160
2.41
5.21
1.1
1.1
—
14.20
titre
—
0
5
11
15
7.55
5.18
1.5
1.1
153.18
171.04
mmol/24h
0.22
11
15
152
1108
1.70
5.18
6.2
4.0
59.77
64.54
e6/l
0.04
127
786
132
927
1.72
5.15
4.3
4.1
6.18
8.07
mg/mmol
0.43
76
582
16
36
4.62
5.13
2.9
3.0
—
—
—
0
0
111
744
1.75
5.11
6.6
4.0
92.51
92.27
%
0.03
105
734
17
50
3.53
5.10
1.2
1.1
—
—
—
0
0
19
61
3.25
5.00
1.4
1.3
292.00
233.87
u/ml
0.28
14
30
10
13
7.90
4.88
1.8
3.8
89.00
208.69
nmol/l
—
10
13
9
10
9.22
4.81
2.3
2.0
—
—
—
0
0
87
554
1.78
4.73
9.2
3.9
140.95
262.90
ng/l
0.47
70
413
75
458
1.83
4.68
1.7
1.7
—
—
—
0
0
15
36
4.32
4.58
2.6
7.8
6.21
6.81
mmol/l
0.56
15
30
61
352
1.90
4.53
3.3
3.1
6.21
7.10
umol/l
0.28
50
312
31
140
2.34
4.34
2.5
2.2
—
—
—
0
0
22
84
2.74
4.33
1.4
4.2
1.23
1.66
ratio
0.57
11
44
87
569
1.72
4.27
3.9
2.8
2.49
2.45
mmol/l
1.35
78
512
9
13
7.09
4.19
1.4
1.2
—
—
%
—
0
0
14
42
3.44
4.09
6.5
2.4
11.57
10.07
mmol/l
0.84
14
42
67
415
1.77
3.95
1.4
1.2
—
—
—
0
0
59
354
1.82
3.87
1.8
1.6
—
—
—
0
0
27
121
2.34
3.86
1.5
2.3
1.51
1.49
g/l
0.03
22
107
39
204
2.04
3.83
1.4
1.3
—
36.27
—
0
16
6
5
12.19
3.77
1.7
1.4
22.67
27.40
%
—
6
5
11
25
4.52
3.65
1.3
1.2
127.45
94.36
pmol/l
1.31
11
25
234
2007
1.60
3.48
6.0
4.1
—
0.00
—
0
5
13
37
3.62
3.44
1.3
1.2
—
—
—
0
0
16
59
2.80
3.37
1.8
1.8
—
—
—
0
0
22
96
2.39
3.35
30.1
9.1
—
—
—
0
0
23
103
2.33
3.31
3.0
1.7
2.30
3149.46
u/l
—
6
31
7
11
6.48
3.20
1.4
1.6
132.29
154.36
nmol/l
—
7
11
13
40
3.34
3.18
1.3
2.4
1.27
0.99
%
—
7
26
87
613
1.57
3.10
1.7
1.3
30.72
26.21
iu/ml
0.14
26
191
13
41
3.26
3.09
1.5
2.4
32.00
32.80
pg
0.32
13
41
7
12
5.94
3.03
1.0
1.0
—
—
—
0
0
11
31
3.64
3.02
1.3
1.1
—
—
—
0
0
151
1204
1.48
2.98
2.7
2.1
—
—
—
0
0
13
46
2.90
2.95
1.7
1.5
—
—
—
0
0
11
32
3.52
2.93
2.6
1.7
—
—
—
0
0
7
13
5.48
2.88
2.0
3.4
236.71
706.85
u/ml
—
7
13
7
13
5.48
2.88
1.0
2.5
—
—
—
0
0
46
280
1.75
2.87
3.3
2.0
0.00
0.05
estimate
0.49
11
57
96
703
1.52
2.85
7.3
3.6
1.02
1.02
kg/l
0.71
65
464
8
18
4.53
2.81
1.3
1.1
—
—
—
0
0
47
290
1.73
2.80
3.3
4.2
2.95
24.63
ug/l
0.78
40
225
9
23
3.99
2.79
1.1
1.2
—
—
—
0
0
20
93
2.23
2.67
2.1
3.8
188.00
213.17
mg/l
—
5
41
107
816
1.46
2.58
1.5
1.5
—
—
—
0
0
10
31
3.29
2.54
1.1
1.0
—
—
—
0
0
10
31
3.29
2.54
2.3
3.1
5.74
3.42
nmol/l
—
10
31
155
1270
1.42
2.52
2.1
1.9
1.64
1.35
mmol/l
2.10
127
1076
12
45
2.73
2.48
2.2
1.4
—
98.12
—
0
6
25
132
1.97
2.43
1.3
1.3
—
—
—
0
0
49
320
1.63
2.37
1.5
1.6
—
—
—
0
0
100
766
1.44
2.32
3.3
3.0
322.66
334.92
umol/l
0.54
85
671
6
13
4.68
2.28
1.5
2.6
2588.33
2041.92
ml
—
6
13
36
220
1.72
2.24
2.7
2.5
3.21
6.35
ug/l
2.27
27
197
12
48
2.56
2.21
1.9
1.6
—
—
—
0
0
12
48
2.56
2.21
1.9
1.6
—
—
—
0
0
12
48
2.56
2.21
1.9
1.6
—
—
—
0
0
12
48
2.56
2.21
1.9
1.6
—
—
—
0
0
9
30
3.06
2.16
1.0
1.1
—
—
—
0
0
8
25
3.25
2.11
1.3
1.2
—
—
—
0
0
14
62
2.31
2.10
1.4
1.3
—
—
—
0
0
114
909
1.39
2.08
6.7
6.7
—
—
—
0
0
5
10
5.06
2.08
1.6
5.7
45.30
47.75
%
—
5
10
5
10
5.06
2.08
4.0
3.0
0.63
0.61
mmol/l
—
5
10
7
20
3.55
2.06
4.6
5.8
16.19
16.26
%
—
7
20
221
2423
0.72
1.92
49.9
19.9
331.93
332.31
g/l
0.23
221
2416
21
114
1.90
1.92
1.7
1.5
—
—
—
0
0
9
34
2.69
1.88
12.9
6.6
9.86
10.66
%
—
9
34
74
557
1.43
1.86
1.7
1.3
9.18
9.69
u/ml
0.03
30
218
6
17
3.58
1.84
1.3
1.3
251.63
78.78
nmol/l
—
6
11
5
12
4.21
1.83
1.4
3.0
3.00
4.66
ug/l
—
5
12
18
96
1.93
1.74
1.7
1.6
—
—
—
0
0
17
90
1.94
1.68
1.5
1.2
—
—
—
0
0
21
120
1.80
1.66
2.0
1.9
—
—
—
0
0
10
41
2.48
1.66
1.0
1.2
—
—
—
0
0
44
306
1.51
1.65
2.2
1.5
—
—
—
0
0
7
26
2.73
1.59
1.6
4.8
6.13
8.43
mmol/l
—
7
26
6
20
3.04
1.59
2.0
1.4
—
—
—
0
0
19
317
0.57
1.56
1.5
1.4
—
—
—
0
0
21
123
1.76
1.55
1.7
1.5
—
—
—
0
0
52
380
1.44
1.54
1.4
1.2
—
—
—
0
0
21
124
1.74
1.51
1.7
1.5
—
—
—
0
0
21
124
1.74
1.51
1.7
1.5
—
—
—
0
0
13
65
2.04
1.51
1.5
2.2
152.50
94.27
ug/min
—
6
33
7
28
2.53
1.46
1.0
1.2
—
—
—
0
0
10
46
2.21
1.41
1.5
1.3
—
—
—
0
0
6
23
2.64
1.37
3.0
2.8
—
—
—
0
0
16
90
1.82
1.35
1.1
1.2
—
—
—
0
0
61
470
1.37
1.34
5.1
3.1
1.65
2.44
e6/l
0.47
38
230
42
303
1.44
1.34
4.4
2.3
29.82
33.64
u/l
0.34
33
247
282
2673
1.42
1.33
5.1
4.3
1.56
1.28
mmol/l
2.32
257
2486
15
84
1.82
1.29
4.9
3.3
0.50
1.76
index
—
10
53
10
49
2.07
1.23
1.3
2.2
—
—
—
0
0
15
86
1.78
1.21
2.9
1.8
—
—
—
0
0
22
142
1.59
1.18
4.5
2.2
0.00
0.02
estimate
—
6
50
7
30
2.36
1.13
1.1
1.2
—
—
—
0
0
22
146
1.54
1.06
2.2
1.5
0.47
0.31
mg/l
—
6
53
7
33
2.15
1.06
2.0
2.7
3.86
4.02
mmol/l
—
7
33
7
33
2.15
1.06
2.0
2.7
1.18
1.18
mmol/l
—
7
33
7
33
2.15
1.06
2.0
2.7
103.57
106.42
mmol/l
—
7
33
7
34
2.08
1.03
4.9
3.4
—
28.68
—
0
12
5
109
0.45
1.02
1.0
1.1
—
0.73
—
0
13
19
124
1.57
0.99
1.6
1.5
—
—
—
0
0
12
69
1.77
0.98
4.0
4.4
—
—
—
0
0
104
1191
0.81
0.96
3.7
3.2
—
—
—
0
0
6
28
2.16
0.92
1.3
1.1
—
—
—
0
0
31
229
1.39
0.91
1.4
1.5
—
—
—
0
0
32
239
1.38
0.88
3.1
2.0
6.21
6.16
ph
0.11
21
155
18
120
1.53
0.87
2.6
3.1
11.88
2092.78
u/ml
1.01
12
99
11
176
0.61
0.82
1.3
1.1
—
—
—
0
0
294
2849
1.34
0.79
6.9
5.8
2.54
2.74
mmol/l
3.15
274
2680
0
26
0.00
0.79
0.0
1.0
—
320.37
—
0
16
36
281
1.32
0.77
1.3
1.2
—
—
—
0
0
16
109
1.49
0.72
2.5
2.8
—
—
—
0
0
7
40
1.77
0.71
2.7
1.7
—
—
—
0
0
7
42
1.68
0.69
1.9
2.0
—
—
—
0
0
5
29
1.74
0.64
1.6
2.1
4.20
5.37
umol/l
—
5
22
5
30
1.68
0.61
1.2
3.6
—
—
—
0
0
88
780
1.18
0.61
5.3
5.5
2.62
2.57
ug/l
0.02
79
699
7
115
0.60
0.59
1.3
1.1
1.49
1.59
g/l
—
7
115
12
81
1.50
0.58
1.3
1.1
—
—
—
0
0
289
2817
1.24
0.54
6.4
5.1
4.47
4.68
mmol/l
2.50
270
2653
34
281
1.23
0.50
1.9
1.8
—
—
—
0
0
287
2809
1.19
0.42
6.2
5.0
1.42
1.49
mmol/l
2.07
265
2629
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
5
34
1.48
0.40
1.2
1.2
—
—
—
0
0
5
36
1.39
0.38
2.4
2.4
—
17.04
—
0
7
6
44
1.37
0.34
1.2
1.1
—
—
—
0
0
11
85
1.30
0.28
2.1
1.7
—
—
—
0
0
32
362
0.87
0.27
2.2
1.5
—
—
—
0
0
12
148
0.80
0.25
1.2
1.1
—
—
—
0
0
23
199
1.17
0.24
1.3
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
6.26
—
0
14
7
61
1.15
0.17
1.0
1.1
—
—
—
0
0
7
61
1.15
0.17
1.0
1.1
—
—
—
0
0
10
120
0.83
0.17
1.9
1.1
1.04
0.94
g/l
—
10
120
6
55
1.09
0.09
1.7
1.1
—
—
—
0
0
7
65
1.08
0.08
1.9
1.2
—
—
—
0
0
48
463
1.04
0.06
3.5
3.1
0.63
0.79
ug/l
1.61
38
287
10
93
1.08
0.02
1.4
1.3
—
—
—
0
0
18
173
1.04
0.01
1.5
1.7
—
—
—
0
0
18
182
0.99
0.00
4.3
2.5
18.36
52.03
u/ml
1.61
18
174
5
50
1.00
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
19.18
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
25.86
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
50.29
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.90
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: E4_CORTICOTROPIN_DEFICIENCY – Corticotropin deficiency

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).