Benign neoplasm: Bones of skull and face

CD2_BENIGN_BONE_SKULL_FACE

oral cavity cancer: A primary or metastatic malignant neoplasm involving the oral cavity. The majority are squamous cell carcinomas.

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

430

4. Check minimum number of events

None

430

5. Include endpoints

None

430

6. Filter based on genotype QC (FinnGen only)

389

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2415 1490 909
Only index persons 2235 1407 828
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.03
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 44.74 46.07 42.50
Only index persons 44.51 45.72 42.46

-FinnGen-

Key figures

All Female Male
Number of individuals 389 295 94
Unadjusted period prevalence (%) 0.09 0.10 0.04
Median age at first event (years) 50.87 49.97 53.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
401
Matched controls
4010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.49
ICD-10 Finland
Bones of skull and face
+∞
307.7
307
*
AAP10
NOMESCO Finland
Extirpation of a skull lesion
962.3
82.6
78
*
D16.40
ICD-10 Finland
Orbital bone
+∞
49.0
46
*
2130A
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Bones of skull and face
+∞
43.5
41
*
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
10.6
41.5
48
51
D16.41
ICD-10 Finland
Benign tumor of the maxillary bone originating in teeth
+∞
16.8
16
*
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
88.6
15.7
17
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.3
14.0
24
40
AA1AD
NOMESCO Finland
CT of head and brain
2.2
11.0
129
721
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.8
10.6
59
235
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.3
9.6
25
61
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
9.2
51
202
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
7.7
9.0
20
27
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
10.4
8.6
16
16
D16.4
ICD-10 Finland
Benign neoplasm: Bones of skull and face
+∞
7.3
7
*
EFA10
NOMESCO Finland
Excision of lesion of jaws
+∞
7.3
7
*
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
4.6
7.2
17
38
EEA10
NOMESCO Finland
Biopsy of maxilla
40.8
6.8
8
*
9102
FHL
Trepanation or removal of the local bone process
17.0
6.8
10
6
S04
ICPC
Lump/swelling localized
2.2
6.5
55
265
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
8.4
6.4
13
16
AAK99
NOMESCO Finland
Other operation on skull or dura
+∞
6.3
6
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
6.1
94
565
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.6
6.1
36
148

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
155
1141
1.58
4.61
2.0
2.3
—
—
—
0
0
190
1500
1.51
3.95
2.3
2.1
—
—
—
0
0
193
1553
1.47
3.53
3.6
3.3
6.11
6.21
ph
0.60
119
886
239
2017
1.46
3.33
5.9
5.0
6.40
6.53
mmol/l
0.60
226
1894
280
2439
1.49
3.30
4.7
4.4
—
2.26
—
0
6
118
870
1.50
3.30
3.8
3.6
—
0.40
—
0
5
120
888
1.50
3.29
3.6
3.8
94.40
94.58
%
0.03
120
870
231
1950
1.44
3.13
4.0
3.7
38.80
7.12
estimate
0.37
41
426
203
1678
1.42
3.07
2.8
2.7
—
—
estimate
—
0
0
79
549
1.55
2.88
1.4
1.4
830.77
500.90
titre
0.36
13
134
227
1936
1.40
2.76
4.0
3.7
0.00
0.00
estimate
0.50
42
420
230
1968
1.40
2.73
4.1
3.8
0.00
0.00
estimate
-0.00
38
401
179
1489
1.37
2.43
4.6
4.8
35.83
36.31
g/l
0.56
166
1415
179
1503
1.34
2.24
4.0
3.5
0.08
0.02
estimate
0.35
38
346
5
9
5.61
2.22
1.2
1.4
0.11
2.99
u/ml
—
5
9
84
627
1.43
2.14
3.6
3.7
24.76
187.01
ng/l
2.36
62
446
41
263
1.62
2.11
2.3
2.5
18.81
14.17
au/ml
—
7
22
372
3538
1.71
2.09
19.3
16.5
3.96
3.94
mmol/l
0.51
365
3454
5
10
5.05
2.07
1.2
1.0
—
—
—
0
0
60
427
1.48
1.96
2.0
1.8
—
—
—
0
0
371
3535
1.66
1.95
19.3
16.3
139.80
139.71
mmol/l
0.37
366
3458
131
1072
1.33
1.89
4.1
3.8
0.00
0.01
estimate
0.74
38
401
6
17
3.57
1.84
1.0
1.1
1109.83
1555.76
miu/ml
—
6
17
107
855
1.34
1.80
4.4
3.7
1.02
1.02
kg/l
0.32
72
558
367
3498
1.58
1.79
16.4
14.4
21.66
21.73
mg/l
0.01
312
2855
65
481
1.42
1.74
1.3
1.2
—
—
—
0
0
0
49
0.00
1.69
0.0
2.4
—
0.91
—
0
27
173
1495
1.28
1.62
2.0
2.0
96.93
98.72
pmol/l
0.19
98
752
108
887
1.30
1.49
2.3
2.7
341.02
325.87
umol/l
0.69
91
794
97
786
1.31
1.47
2.5
2.4
8.17
6.80
e6/l
0.22
86
717
12
59
2.07
1.45
1.0
1.0
5.74
0.78
u/ml
—
6
29
97
789
1.30
1.43
1.4
1.3
22.72
37.30
iu/ml
0.64
33
248
291
2700
1.28
1.43
7.6
8.0
79.40
77.82
u/l
0.15
278
2569
127
1071
1.27
1.42
3.0
2.9
—
—
—
0
0
23
142
1.66
1.42
8.7
5.3
0.95
0.87
%
0.67
23
135
193
1711
1.25
1.40
7.5
6.8
1.21
1.22
mmol/l
1.23
167
1495
134
1141
1.26
1.38
2.9
3.0
17.82
108.69
e6/l
0.89
100
853
155
1343
1.25
1.37
3.5
3.6
35.63
75.48
e6/l
1.44
102
912
12
61
2.00
1.34
1.0
1.0
4.50
1.27
u/ml
—
7
29
11
54
2.07
1.34
1.0
1.0
7.67
2.65
u/ml
—
6
25
125
1060
1.26
1.32
2.3
2.1
142.15
185.00
u/l
0.92
119
1009
50
376
1.38
1.25
12.5
8.2
13.83
12.47
kpa
1.00
50
367
50
376
1.38
1.25
12.5
8.2
5.18
5.20
kpa
0.07
50
365
146
1268
1.24
1.24
2.7
3.2
2.36
2.36
mmol/l
0.13
134
1158
5
19
2.65
1.22
1.2
1.1
—
—
—
0
0
24
157
1.56
1.20
8.1
5.0
1.78
1.57
%
0.50
24
150
12
64
1.90
1.19
1.0
1.0
14.61
7.10
u/ml
—
7
34
16
94
1.73
1.19
1.0
1.0
—
—
—
0
0
38
277
1.41
1.15
1.2
1.2
215.79
292.22
u/ml
0.28
38
258
14
80
1.78
1.14
1.6
1.9
—
—
—
0
0
49
376
1.35
1.10
12.7
8.3
7.42
7.42
ph
0.15
27
218
8
41
1.97
1.09
1.3
1.4
307.10
292.18
mu/l
—
8
33
167
1489
1.21
1.07
9.5
11.2
1.22
1.17
inr
0.51
133
1243
28
196
1.46
1.05
9.1
7.1
25.68
24.91
mmol/l
0.62
28
191
115
991
1.22
1.04
2.6
2.9
0.51
0.46
e6/l
0.05
81
703
87
729
1.25
1.02
1.3
1.3
8.69
11.18
u/ml
0.13
40
294
55
436
1.30
1.00
10.1
6.9
104.58
104.32
mmol/l
0.17
55
436
52
409
1.31
1.00
1.8
1.6
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
132
1161
1.20
0.97
3.0
3.2
7.89
7.48
mmol/l
0.39
113
983
38
287
1.36
0.96
1.6
1.4
—
—
—
0
0
14
85
1.67
0.95
4.0
3.2
3.80
1.29
index
—
5
48
6
28
2.16
0.92
1.3
1.2
—
—
—
0
0
83
703
1.23
0.88
2.5
2.7
2.43
2.44
mmol/l
0.64
74
630
388
3809
1.57
0.83
24.4
22.1
259.49
257.08
e9/l
0.34
382
3740
119
1050
1.19
0.83
3.8
3.8
7.39
7.40
ph
0.65
79
746
8
46
1.75
0.83
3.0
2.8
—
—
—
0
0
52
421
1.27
0.82
2.4
2.9
18.66
6.18
umol/l
0.79
43
365
372
3627
1.35
0.82
14.3
12.8
—
—
—
0
0
168
1529
1.17
0.81
7.7
6.2
1.20
1.22
mmol/l
1.34
157
1422
301
2871
1.19
0.80
5.0
4.5
14.68
14.61
pmol/l
0.22
285
2646
120
1063
1.18
0.80
3.1
3.3
40.25
48.24
mg/l
0.21
75
663
6
33
1.83
0.79
1.2
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
4.9
—
7.55
—
0
25
388
3812
1.55
0.79
24.3
22.1
6.71
6.61
e9/l
0.41
380
3731
388
3812
1.55
0.79
24.3
22.0
4.50
4.48
e12/l
0.42
380
3736
0
27
0.00
0.77
0.0
16.9
—
914.33
—
0
27
6
34
1.78
0.76
1.2
1.1
129.33
110.15
pmol/l
—
6
34
124
1106
1.18
0.76
3.4
3.1
0.03
0.01
estimate
0.29
37
340
8
132
0.60
0.75
1.4
1.3
—
—
—
0
0
9
56
1.62
0.73
1.1
1.1
—
—
—
0
0
78
671
1.20
0.72
2.3
2.6
505.91
523.60
mosm/kgh2o
0.25
66
588
16
109
1.49
0.72
1.4
1.7
—
—
—
0
0
106
938
1.18
0.72
3.2
3.1
1353.22
1024.34
ng/l
0.33
93
783
7
40
1.76
0.71
1.1
1.5
27.61
23.62
ng/l
—
7
40
132
1191
1.16
0.70
5.4
5.9
—
—
—
0
0
28
214
1.33
0.69
17.0
8.6
24.53
24.98
mmol/l
0.37
28
214
93
817
1.18
0.69
1.9
1.7
1.30
1.08
mg/l
0.32
81
638
7
42
1.68
0.68
3.1
2.0
—
—
—
0
0
121
1088
1.16
0.67
3.6
4.0
6.62
8.28
mg/mmol
0.24
80
650
5
28
1.80
0.66
1.4
3.0
—
—
—
0
0
5
28
1.80
0.66
1.2
1.1
—
4.36
—
0
7
19
137
1.41
0.66
1.4
1.6
74.66
58.61
ug/l
0.68
19
115
29
225
1.31
0.65
1.7
1.7
—
—
—
0
0
8
127
0.62
0.65
1.4
2.2
1.24
1.41
g/l
—
8
112
355
3459
1.23
0.63
5.1
4.9
4.74
4.76
mmol/l
0.16
333
3251
10
63
1.60
0.62
1.1
1.2
—
—
—
0
0
29
365
0.78
0.61
2.6
3.0
0.50
0.77
ug/l
2.40
16
241
15
105
1.45
0.61
1.5
1.6
—
—
—
0
0
311
3001
1.16
0.59
18.7
17.8
13.62
13.54
%
0.42
305
2972
342
3325
1.19
0.59
6.0
5.5
1.73
1.86
mu/l
1.56
329
3092
334
3247
1.17
0.54
6.0
5.9
38.46
38.67
mmol/mol
0.18
319
3077
6
38
1.59
0.54
1.0
1.2
7.49
1.84
u/ml
—
6
17
6
100
0.59
0.52
1.3
2.6
—
—
—
0
0
10
145
0.68
0.51
4.3
4.5
—
—
—
0
0
21
162
1.31
0.51
1.2
1.2
—
—
—
0
0
9
65
1.39
0.51
3.2
3.6
4.18
4.38
e9/l
—
9
65
124
1139
1.13
0.50
2.8
2.5
54.59
61.84
u/l
0.85
117
1066
11
76
1.46
0.48
1.1
1.2
—
—
—
0
0
17
129
1.33
0.46
1.3
1.1
1.53
1.58
g/l
0.37
17
129
8
121
0.65
0.46
3.3
1.3
—
—
—
0
0
200
1898
1.11
0.45
6.5
6.3
11.54
11.09
umol/l
0.14
193
1811
10
69
1.46
0.44
1.0
1.2
—
—
—
0
0
197
1869
1.11
0.44
5.7
6.2
0.56
0.55
e9/l
0.10
170
1615
57
501
1.16
0.44
1.3
1.2
—
—
—
0
0
7
51
1.38
0.44
1.1
1.6
—
—
—
0
0
7
51
1.38
0.44
1.1
1.6
—
—
—
0
0
7
51
1.38
0.44
1.1
1.6
—
—
—
0
0
7
51
1.38
0.44
1.1
1.6
—
—
—
0
0
54
474
1.16
0.43
1.4
1.3
—
—
—
0
0
5
32
1.57
0.42
1.2
3.9
8.52
11.08
%
—
5
32
164
1545
1.10
0.42
1.9
1.9
1.44
1.36
mmol/l
0.44
142
1303
204
1943
1.10
0.42
5.6
6.5
0.20
0.18
e9/l
0.64
179
1714
25
204
1.24
0.41
1.1
1.1
—
—
—
0
0
5
33
1.52
0.41
1.8
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
0.00
—
0
15
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
18
141
1.29
0.41
2.2
1.9
21.28
21.06
s
0.06
18
131
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
7
102
0.68
0.40
9.1
4.8
62.47
47.67
mg/l
—
7
89
7
102
0.68
0.40
9.1
4.8
46.97
26.37
mg/l
—
7
88
35
298
1.19
0.40
1.2
1.5
—
—
—
0
0
356
3496
1.16
0.40
5.7
5.6
2.80
2.80
mmol/l
0.05
337
3279
5
35
1.43
0.39
4.4
1.7
93.26
89.72
%
—
5
35
372
3666
1.20
0.39
12.1
11.6
25.16
25.25
u/l
0.04
364
3574
197
1878
1.10
0.39
5.7
6.2
0.04
0.04
e9/l
0.28
170
1621
76
689
1.13
0.39
1.9
1.7
440.13
32258507.31
pmol/l
0.77
67
589
12
89
1.36
0.38
2.8
3.3
56.35
57.83
%
0.18
12
89
20
161
1.25
0.38
1.5
1.3
251.82
264.54
miu/ml
0.07
11
80
38
328
1.18
0.37
1.2
1.1
—
—
—
0
0
17
134
1.28
0.37
1.3
1.2
0.83
0.89
g/l
0.95
17
134
254
2454
1.10
0.37
3.1
3.3
36.72
44.15
u/l
1.46
238
2328
37
426
0.86
0.36
1.1
1.4
—
—
—
0
0
351
3448
1.14
0.36
4.9
4.8
1.51
1.52
mmol/l
0.25
328
3228
6
41
1.47
0.36
1.0
1.0
—
—
—
0
0
31
264
1.19
0.36
14.0
9.0
—
—
—
0
0
56
501
1.14
0.35
1.8
1.6
1149.68
1231.37
nmol/l
0.26
44
373
27
231
1.18
0.30
1.6
1.6
773.68
978.89
mu/l
0.94
27
197
335
3290
1.11
0.30
4.3
4.1
1.25
1.26
mmol/l
0.11
315
3059
15
120
1.26
0.30
2.1
1.7
0.18
3.47
ug/l
0.84
15
110
59
536
1.12
0.30
2.4
2.8
3.35
3.02
e6/l
0.12
22
233
140
1473
0.92
0.30
2.8
3.1
—
—
—
0
0
36
317
1.15
0.29
1.8
2.0
0.00
0.04
estimate
—
5
81
44
489
0.89
0.28
1.7
1.5
—
—
—
0
0
36
405
0.88
0.28
1.4
1.4
—
—
—
0
0
14
113
1.25
0.27
1.6
1.3
235.96
317.91
ug/g
—
7
67
25
288
0.86
0.26
3.1
4.1
7.31
7.37
ph
0.38
20
212
50
455
1.11
0.26
3.1
3.5
4.51
4.94
e9/l
0.29
42
412
132
1258
1.07
0.25
3.6
3.2
28.59
29.70
u/l
0.22
127
1197
10
78
1.29
0.24
1.1
1.1
—
—
—
0
0
10
78
1.29
0.24
1.1
1.1
—
—
—
0
0
6
84
0.71
0.24
3.3
3.9
—
—
—
0
0
106
1005
1.07
0.23
1.6
1.6
21.04
20.93
nmol/l
0.03
94
860
14
168
0.83
0.23
1.1
1.5
—
—
—
0
0
80
851
0.93
0.23
2.0
1.4
2.06
2.26
g/l
0.66
47
524
5
40
1.25
0.22
3.2
1.4
—
—
—
0
0
13
107
1.22
0.22
1.1
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
4.4
—
0.60
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
5.4
—
8.73
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
8
104
0.76
0.21
3.0
3.5
1.85
1.38
mg/l
—
8
91
0
12
0.00
0.21
0.0
2.0
—
0.48
—
0
12
14
166
0.84
0.21
2.1
2.1
0.00
0.01
estimate
—
5
67
0
13
0.00
0.21
0.0
1.1
—
37.42
—
0
6
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.59
—
0
7
0
14
0.00
0.20
0.0
2.4
—
4.06
—
0
14
6
49
1.23
0.20
1.0
3.4
0.33
1.36
%
—
6
44
20
174
1.16
0.20
2.6
2.3
2523.51
4286.27
u/l
—
9
72
39
356
1.11
0.20
2.1
2.8
1.65
1.83
%
0.80
34
323
11
133
0.82
0.19
2.7
1.6
1.23
1.20
g/l
0.14
11
127
197
1917
1.05
0.19
5.9
6.2
1.89
1.92
e9/l
0.13
171
1705
6
53
1.13
0.18
1.2
1.0
—
—
—
0
0
6
53
1.13
0.18
1.2
1.7
183.00
212.36
pmol/l
—
6
47
25
223
1.13
0.18
3.3
2.7
—
—
—
0
0
23
204
1.14
0.18
1.5
1.2
—
—
—
0
0
7
60
1.17
0.18
1.9
1.4
—
—
—
0
0
7
61
1.15
0.17
2.0
2.0
—
—
—
0
0
8
72
1.11
0.16
1.0
1.6
—
—
—
0
0
6
77
0.78
0.15
1.0
1.5
—
—
—
0
0
54
508
1.07
0.15
2.6
1.9
—
—
—
0
0
40
372
1.08
0.15
1.6
1.4
—
—
—
0
0
190
1856
1.05
0.15
3.4
3.1
100.73
95.68
ug/l
0.14
178
1751
47
441
1.07
0.14
1.6
1.8
—
—
—
0
0
19
170
1.12
0.13
1.8
1.9
—
—
—
0
0
9
108
0.83
0.13
1.1
1.8
—
—
—
0
0
21
190
1.11
0.13
1.9
2.2
13.47
12.69
nmol/l
0.18
21
174
134
1303
1.04
0.13
3.5
3.5
21.58
35.64
ng/l
1.58
74
863
32
343
0.93
0.12
4.1
4.5
0.40
0.92
%
—
10
102
15
168
0.89
0.12
1.1
1.5
—
—
—
0
0
11
95
1.16
0.11
1.8
1.3
—
—
—
0
0
340
3374
1.05
0.10
5.2
4.7
5.79
5.82
mmol/l
0.20
313
3136
32
341
0.93
0.10
3.9
4.4
160.62
38.43
ug/l
0.49
23
281
15
166
0.90
0.10
1.1
1.5
—
—
—
0
0
12
106
1.14
0.10
1.2
1.2
—
—
—
0
0
5
45
1.11
0.10
2.0
2.4
—
—
—
0
0
170
1731
0.97
0.09
6.0
6.1
58.41
56.89
%
1.13
163
1653
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
5
47
1.06
0.09
1.2
1.3
—
—
—
0
0
15
165
0.91
0.09
1.1
1.5
—
—
—
0
0
7
65
1.08
0.08
9.9
2.4
9.50
8.59
kpa
—
7
65
7
65
1.08
0.08
9.9
2.4
5.00
5.13
kpa
—
7
65
12
133
0.90
0.08
1.0
1.5
—
—
—
0
0
6
71
0.84
0.07
2.0
3.7
32.17
35.15
umol/l
—
6
64
55
531
1.04
0.07
2.1
2.4
80.54
106.28
ug/g
0.91
41
414
167
1646
1.02
0.07
2.7
2.5
77.15
77.21
nmol/l
0.01
154
1496
212
2097
1.02
0.06
8.1
9.6
4.36
3.97
e9/l
1.35
182
1831
87
890
0.97
0.06
4.5
4.3
—
—
—
0
0
110
1080
1.03
0.06
1.6
1.5
—
—
—
0
0
32
306
1.05
0.06
1.3
1.2
85.11
139.38
u/ml
—
9
130
33
344
0.96
0.05
1.6
1.8
3.40
3.40
mmol/l
0.00
22
250
174
1720
1.02
0.05
5.9
6.2
8.42
8.68
%
0.72
163
1618
98
962
1.02
0.05
1.3
1.3
0.81
2.11
u/ml
1.31
30
260
68
665
1.03
0.04
1.9
1.7
—
—
—
0
0
166
1644
1.02
0.04
10.0
11.2
0.00
0.00
e9/l
0.79
128
1347
29
301
0.96
0.04
5.0
3.8
1.31
2.14
mmol/l
0.71
23
256
31
321
0.96
0.03
4.1
4.7
0.00
0.17
%
—
9
78
173
1716
1.01
0.03
5.9
6.2
0.65
0.71
%
0.80
162
1602
105
1063
0.98
0.03
4.6
6.1
—
—
—
0
0
31
301
1.03
0.02
3.6
3.6
—
—
—
0
0
15
158
0.95
0.02
1.1
1.5
—
—
—
0
0
17
178
0.95
0.02
1.8
1.8
4.07
6.40
iu/ml
—
10
45
26
268
0.97
0.02
1.3
1.2
—
—
—
0
0
12
113
1.06
0.02
7.2
6.6
—
—
—
0
0
12
127
0.94
0.01
1.8
1.6
—
—
—
0
0
33
323
1.02
0.01
2.5
2.4
0.22
0.22
g/l
0.08
33
305
33
323
1.02
0.01
3.9
4.5
0.69
0.61
%
0.07
13
87
92
913
1.01
0.01
4.9
4.9
—
—
—
0
0
10
106
0.94
0.01
8.1
2.6
7.39
7.42
ph
—
10
106
15
156
0.96
0.00
2.1
2.4
—
—
—
0
0
16
166
0.96
0.00
4.7
3.6
0.89
1.20
%
1.29
16
166
32
314
1.02
0.00
5.5
3.7
7.38
7.38
ph
0.00
16
183
35
344
1.02
0.00
2.3
2.3
40.30
33.70
u/l
0.24
30
291
10
99
1.01
0.00
2.2
1.9
400.64
241.42
ug/l
—
10
93
77
768
1.00
0.00
2.2
2.0
—
—
—
0
0
20
199
1.01
0.00
1.1
1.1
—
104.43
—
0
7
172
1718
1.00
0.00
5.8
6.1
2.71
2.79
%
0.17
162
1610
27
271
1.00
0.00
2.6
3.0
63.61
73.07
e9/l
1.05
20
200
176
1756
1.00
0.00
6.0
6.2
27.47
28.66
%
0.83
166
1668
16
163
0.98
0.00
5.1
3.5
0.53
0.61
%
0.51
16
163
33
327
1.01
0.00
4.0
5.0
0.18
0.25
%
0.15
11
71
29
285
1.02
0.00
2.4
2.3
6.02
6.16
ph
0.43
20
182
92
924
0.99
0.00
2.6
2.2
2.45
2.85
mg/l
1.47
86
815
45
455
0.99
0.00
1.8
1.5
—
—
—
0
0
18
176
1.02
0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
50.29
—
0
7
0
7
0.00
0.00
0.0
1.1
—
86.81
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
0.00
1.0
1.1
—
—
—
0
0
6
67
0.89
0.00
2.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
172.43
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
1.70
—
0
7
6
68
0.88
-0.00
10.5
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
0.23
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
13
130
1.00
-0.00
1.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.3
0.16
0.18
nmol/l
—
5
36
0
6
0.00
-0.00
0.0
2.8
—
2.50
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.50
—
0
5
5
51
0.98
-0.00
1.4
1.3
8.14
16.23
u/l
—
5
44
7
77
0.91
-0.00
1.1
2.6
3.47
8.57
pmol/l
—
7
77
0
6
0.00
-0.00
0.0
2.3
—
20.32
—
0
6
0
8
0.00
-0.00
0.0
3.6
—
43.69
—
0
8
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
2.61
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
33.64
—
0
8

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_BONE_SKULL_FACE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_SKULL_FACE 1.02 [0.82, 1.26] 0.858
Birth year 1.001 [0.99, 1.01] 0.875

During the follow-up period (1.1.1998 — 31.12.2019), 106 out of 1100 females with CD2_BENIGN_BONE_SKULL_FACE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BONE_SKULL_FACE 0.96 [0.73, 1.26] 0.769
Birth year 0.99 [0.98, 1.0] 0.056

During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 659 males with CD2_BENIGN_BONE_SKULL_FACE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BONE_SKULL_FACE.

N-year risk Females Males
1 0.069% 0.218%
5 0.548% 1.183%
10 1.618% 2.989%
15 3.316% 5.825%
20 6.126% 9.559%

Relationships between endpoints

Index endpoint: CD2_BENIGN_BONE_SKULL_FACE – Benign neoplasm: Bones of skull and face

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data