Disorders related to long gestation and high birth weight

P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P08 Cause of death: ICD-10 — P08 2 out of 7 registries used, show all original rules.	99
4. Check minimum number of events None	99
5. Include endpoints None	99
6. Filter based on genotype QC (FinnGen only)	91

Control definitions (FinnGen only)

Control exclude: P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P0[5-8]
Name in latin: Perturbationes ad gestationem longum et pondus partuale grave pertinentes

NAME	P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT
CONTROL_EXCLUDE	P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P08
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P08
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Disorders related to long gestation and high birth weight based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	6743	2756	3986
Only index persons	2770	1116	1654
Unadjusted period prevalence (%)
Whole population	0.10	0.08	0.11
Only index persons	0.05	0.04	0.06
Median age at first event (years)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	91	54	37
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
92: Matched controls
920

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

P08.0

ICD-10 Finland

Exceptionally large baby

+∞

50.8

P08.1

ICD-10 Finland

Other heavy for gestational age infants

+∞

45.7

P07.3

ICD-10 Finland

Other preterm infants

+∞

21.7

P70.1

ICD-10 Finland

Syndrome of infant of a diabetic mother

84.0

18.6

P70.4

ICD-10 Finland

Other neonatal hypoglycaemia

23.1

16.2

P08.2

ICD-10 Finland

Post-term infant, not heavy for gestational age

+∞

15.0

Z87.6

ICD-10 Finland

Personal history of certain conditions arising in the perinatal period

19.9

12.3

P22.1

ICD-10 Finland

Transient tachypnoea of newborn

10.6

7.1

P70.0

ICD-10 Finland

Syndrome of infant of mother with gestational diabetes

12.3

7.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

3.49

1.77

6.5

6.1

2.23

6.57

u/ml

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

132

0.42

1.42

2.5

2.0

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

1.18

0.0

1.4

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

1.18

0.0

1.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.21

1.08

2.4

2.3

—

(46236952) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)/1.73 sq M

0.00

0.99

0.0

3.2

—

90.00

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.89

0.88

2.4

2.1

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

0.49

0.84

22.2

16.1

106.60

105.60

mmol/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

238

0.65

0.82

2.9

3.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

134

0.56

0.81

1.6

1.9

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.80

0.0

1.1

—

1.25

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.80

0.0

2.0

—

(40758558) Short blood count panel - Blood

311

0.69

0.78

18.3

10.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

156

0.60

0.76

1.5

2.4

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

1.72

0.72

1.5

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

1.97

0.72

1.0

160.60

168.15

g/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

252

0.69

2.8

2.7

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

429

0.74

0.69

2.7

2.1

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

174

0.64

0.67

1.6

2.5

—

(3013512) EKG study

101

0.57

0.67

1.5

2.9

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.64

0.67

1.3

1.0

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

105

0.54

0.66

1.0

2.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

779

0.70

0.63

4.0

3.9

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

383

0.75

0.61

1.9

2.0

0.42

4.39

u/ml

—

(3008295) Osmolality of Serum or Plasma

0.00

0.61

0.0

1.2

—

297.40

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.61

0.0

4.6

—

17.02

—

(3020891) Body temperature

0.00

0.61

0.0

7.7

—

36.93

—

(3000494) Fungus identified in Specimen by Culture

0.55

0.59

1.2

2.1

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.59

0.0

7.9

—

63.33

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

1.76

0.59

2.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

1.66

0.57

1.8

1.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

470

1.30

0.56

2.3

2.5

5.26

5.24

mmol/l

0.09

426

(3044640) Blood type and Crossmatch panel - Blood

205

0.73

0.47

4.8

4.5

—

(3022313) Gas panel - Capillary blood

186

1.32

0.46

10.5

11.8

—

(3015736) pH of Urine

331

0.78

0.46

2.5

3.7

6.67

6.38

—

151

(3042936) Bacteria identified in Isolate by Culture

0.61

0.45

1.8

1.9

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

171

0.72

0.44

4.8

4.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

171

0.72

0.44

4.1

6.5

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

1.65

0.44

2.4

2.2

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.41

0.0

1.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

2.7

—

(40761873) Peanut recombinant (rAra h) 1 IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.2

—

0.65

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.5

—

(4062490) Immunoglobulin typing, IgG

0.00

0.41

0.0

1.2

—

(3027653) Mycophenolate [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

7.4

—

2.10

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.41

0.0

1.1

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.41

0.0

1.1

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

9.9

—

4.95

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.50

0.41

1.0

1.2

—

(40761511) CBC panel - Blood by Automated count

741

1.35

0.40

8.0

9.4

—

(3027945) Reticulocytes/Erythrocytes in Blood

125

1.34

0.40

5.7

8.5

1.38

0.01

119

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.40

0.0

2.2

—

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

0.00

0.40

0.0

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

1.45

0.40

1.2

1.3

—

(1761868) Lipid panel - Serum or Plasma

153

1.30

0.39

1.6

2.3

—

(44790049) Parainfluenza type 3 nucleic acid detection

1.41

0.39

2.4

2.1

—

(44790048) Parainfluenza type 2 nucleic acid detection

1.41

0.39

2.4

2.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

1.41

0.39

1.2

1.3

—

(44806118) Parainfluenza type 4 nucleic acid detection

1.41

0.39

2.4

2.1

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

1.41

0.39

2.4

2.2

—

(44790047) Parainfluenza type 1 nucleic acid detection

1.41

0.39

2.4

2.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

108

1.35

0.38

2.6

2.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

251

0.79

0.37

2.0

2.4

—

(3019150) Specific gravity of Urine by Refractometry

197

0.77

0.35

2.3

3.2

1.02

kg/l

—

136

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.64

0.34

11.8

13.1

97.83

92.60

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.36

0.34

1.5

1.7

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.33

0.34

2.3

2.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

195

0.78

0.33

10.0

14.1

1.40

1.36

mmol/l

0.19

186

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

237

0.80

0.33

2.5

2.6

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

1.40

0.32

3.6

4.9

15.86

24.12

nmol/l

—

(3021706) Oxygen [Partial pressure] in Arterial cord blood

1.35

0.31

1.0

2.44

3.17

kpa

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

267

0.82

0.31

4.3

—

estimate

—

(3006598) pH of Arterial cord blood

1.29

0.31

1.0

—

(3003932) Carbon dioxide [Partial pressure] in Arterial cord blood

1.29

0.31

1.0

8.64

7.56

kpa

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

1.29

0.31

1.0

17.86

19.44

mmol/l

—

(40761536) Microorganisms panel - Urine sediment

1.27

0.30

1.9

4.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.34

0.29

1.4

1.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

265

0.82

0.29

2.0

3.4

0.00

estimate

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

417

0.85

0.28

4.4

8.6

111.61

113.73

ml/min/173m2

0.29

323

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

0.68

0.27

14.0

9.3

144.40

170.42

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

1.37

0.24

1.4

1.5

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

1.37

0.24

1.4

1.5

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

0.76

0.24

3.4

5.3

0.17

0.21

g/l

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

1.33

0.23

1.8

1.6

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.33

0.23

4.6

2.8

4.86

5.22

pmol/l

—

(3021589) Normoblasts [#/volume] in Blood

467

1.15

0.23

14.0

0.00

0.03

e9/l

0.45

345

(3020961) Endomysium IgA Ab [Titer] in Serum

123

0.79

0.22

1.0

1.5

—

55.83

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

521

0.87

0.22

16.3

13.6

3.33

3.50

e9/l

0.20

428

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

737.09

—

(3016031) Almond IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.5

—

2.03

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.21

0.0

1.0

—

(3024471) HLA-A [Type]

0.00

0.21

0.0

1.0

—

(3024932) HLA-DR beta [Type]

0.00

0.21

0.0

1.0

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.21

0.0

1.0

—

(3013924) Clostridium tetani IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.4

—

0.74

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.21

0.0

1.0

—

(3032390) JC virus DNA [#/volume] (viral load) in Urine by NAA with probe detection

0.00

0.21

0.0

5.8

—

(36203922) Streptococcus pneumoniae Danish serotype 14 IgG Ab [Mass/volume] in Serum

0.00

0.21

0.0

1.3

—

1.79

—

(40768446) Kidney Pathology biopsy report

0.00

0.21

0.0

3.5

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

7.8

—

8.00

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.21

0.0

2.3

—

1.40

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

71.77

—

(4268621) Lupus anticoagulant assay

0.00

0.21

0.0

2.2

—

(3042733) HLA Ab [Presence] in Serum

0.00

0.21

0.0

2.4

—

(44813793) Dust mix specific IgE antibody measurement

0.00

0.20

0.0

1.0

—

(40761871) Peanut recombinant (rAra h) 3 IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.2

—

2.48

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.21

0.20

1.2

1.4

3.40

3.30

ratio

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

100

1.23

0.19

6.3

11.3

5.33

5.69

umol/l

0.13

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.22

0.18

1.7

1.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.24

0.18

2.1

2.2

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

204

0.85

0.18

14.1

11.7

5.63

5.73

kpa

0.18

199

(3012544) pH of Venous blood

204

0.85

0.18

14.1

11.8

7.39

7.37

0.88

132

(3016879) Cocaine [Presence] in Urine

120

0.81

0.18

1.1

2.1

—

(3006315) Basophils [#/volume] in Blood

487

0.89

0.17

12.2

11.9

0.04

e9/l

0.20

396

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.22

0.17

2.1

2.2

—

(3002030) Lymphocytes/Leukocytes in Blood

486

0.89

0.17

12.3

11.9

35.63

36.12

0.09

474

(42870560) Thyrotropin [Units/volume] in Cord blood

1.19

0.16

1.0

11.42

8.91

mu/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

394

0.90

0.15

2.5

4.1

0.00

estimate

—

(3013115) Eosinophils [#/volume] in Blood

504

0.90

0.15

13.4

12.6

0.20

e9/l

0.06

425

(3028300) Cannabinoids [Presence] in Urine

127

0.85

0.13

1.1

2.1

—

(3003694) ABO and Rh group [Type] in Blood

250

0.89

0.13

1.7

—

(3000764) Benzodiazepines [Presence] in Urine

126

0.86

0.12

1.1

2.1

—

(3027008) Opiates [Presence] in Urine

126

0.86

0.12

1.1

2.0

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

659

0.91

0.12

3.8

4.2

1.98

2.03

mu/l

0.12

626

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

212

1.11

0.11

13.3

11.9

1.42

0.88

mmol/l

0.40

156

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

187

0.89

0.11

1.6

1.9

—

(42868678) Cholesterol non HDL [Moles/volume] in Serum or Plasma

1.14

0.10

1.0

1.3

3.34

3.18

mmol/l

—

(3001604) Monocytes [#/volume] in Blood

488

0.92

0.10

12.0

11.8

0.60

0.55

e9/l

0.34

397

(3027944) Amphetamines [Presence] in Urine

124

0.87

0.09

1.1

2.1

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

165

0.89

0.09

2.2

1.6

84.81

95.00

pmol/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

293

1.09

0.09

2.3

2.0

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

224

1.10

0.09

19.3

24.42

24.44

mmol/l

0.02

224

(3035350) Ketones [Presence] in Urine by Test strip

397

0.93

0.09

2.6

4.1

0.00

estimate

—

(3010813) Leukocytes [#/volume] in Blood

863

0.95

0.09

19.9

20.7

6.81

6.98

e9/l

0.28

814

(3026361) Erythrocytes [#/volume] in Blood

862

0.96

0.08

19.8

20.7

4.59

4.57

e12/l

0.15

815

(3000492) Spirometry study

0.81

0.08

1.4

1.3

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.80

0.08

2.2

1.6

—

(42870588) Differential panel, method unspecified - Blood

364

1.07

0.08

15.1

12.4

—

(3019198) Lymphocytes [#/volume] in Blood

496

0.93

0.08

11.9

11.8

2.24

2.36

e9/l

0.37

421

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.81

0.08

1.5

1.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.03

0.07

1.0

1.4

—

(3026008) Bacteria identified in Urine by Culture

193

0.92

0.07

2.1

2.7

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

727

1.09

0.07

8.9

12.8

55.74

56.15

umol/l

0.06

712

(3011288) Drugs identified in Urine by Screen method Nominal

0.84

0.07

1.0

2.4

—

(3018010) Neutrophils/Leukocytes in Blood

474

0.94

0.06

12.0

11.8

50.04

48.66

0.26

465

(3029937) Albumin [Presence] in Urine by Test strip

192

0.92

0.06

2.1

4.1

0.00

estimate

—

(3044889) 12 lead EKG panel

313

0.94

0.06

2.2

2.3

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

129

0.92

0.04

1.0

1.1

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

749

0.94

0.03

18.6

19.9

13.47

13.09

1.19

742

(3048689) Calprotectin [Mass/mass] in Stool

198

0.95

0.02

2.4

3.4

54.40

63.53

ug/g

—

162

(36660697) Celiac disease serology panel - Serum

173

1.05

0.01

1.4

1.3

—

(3023368) Bacteria identified in Blood by Culture

134

1.05

0.00

5.4

5.2

—

(40768804) Tissue Pathology biopsy report

144

1.05

0.00

1.5

1.7

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

694

1.04

0.00

16.1

16.9

139.04

139.39

mmol/l

0.66

681

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

284

1.03

0.00

5.0

5.8

—

(3009261) Glucose [Presence] in Urine by Test strip

396

0.97

0.00

2.5

4.2

0.00

estimate

—

(3007853) Bacteria identified in Skin by Aerobe culture

118

1.02

0.00

1.8

2.0

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

778

1.02

0.00

11.3

14.3

22.38

23.95

mg/l

0.20

559

(3019832) Treponema pallidum Ab [Presence] in Serum

163

0.98

0.00

1.7

2.0

—

(3000991) Gas panel - Venous blood

193

0.98

0.00

13.9

16.0

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

597

1.01

0.00

3.3

3.6

13.81

14.48

pmol/l

1.57

541

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

196

1.03

0.00

12.7

11.5

22.85

23.36

mmol/l

0.31

196

(3041096) Erythrocytes [Presence] in Urine by Automated

191

0.99

0.00

2.1

3.3

0.00

estimate

—

(3007164) IgA [Mass/volume] in Serum or Plasma

356

1.02

0.00

1.4

2.0

1.50

1.46

g/l

0.08

185

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

-0.00

0.0

1.1

—

166.56

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.3

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.02

-0.00

1.6

1.5

731.10

1022.84

mu/l

—

(3035400) Alkaline phosphatase.liver [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

128.00

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

-0.00

0.0

2.0

—

19.15

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3045684) Alkaline phosphatase.other fractions [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

10.00

—

(3009595) Pneumocystis jirovecii DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3021578) Parainfluenza virus 2 Ag [Presence] in Specimen

0.00

-0.00

0.0

1.5

—

(3004905) Lipase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

3.9

—

18.29

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.0

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

3.3

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

1.4

—

(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk

0.00

-0.00

0.0

1.1

—

1.50

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

1.0

—

(3005880) Parainfluenza virus 3 Ag [Presence] in Specimen

0.00

-0.00

0.0

1.5

—

(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.3

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3001467) Alkaline phosphatase.bone [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

439.75

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.7

—

60.86

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3010464) Parainfluenza virus 1 Ag [Presence] in Specimen

0.00

-0.00

0.0

1.5

—

(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(1002224) Polysomnography panel

0.00

-0.00

0.0

1.0

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3040370) OLANZapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.2

—

224.83

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.4

—

3.81

—

(4034850) Laboratory test

0.00

-0.00

0.0

5.1

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(3007302) Hemoglobin [Mass/volume] in Mixed venous blood

0.00

-0.00

0.0

2.4

—

94.13

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

-0.00

0.0

4.6

—

(4211845) Urine protein measurement

0.00

-0.00

0.0

1.4

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

1.23

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

-0.00

0.0

2.4

—

4.99

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.2

—

1.02

—

(3037522) Nuclear Ab [Titer] in Serum

0.90

-0.00

1.2

1.7

—

524.44

—

(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.0

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

0.48

—

(3036603) Volume of Urine

0.00

-0.00

0.0

1.5

—

1560.83

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

2.0

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

140.21

—

(3011048) Pyruvate [Moles/volume] in Blood

0.00

-0.00

0.0

1.1

—

104.67

—

(3019897) Erythrocyte [DistWidth] in Red Blood Cells by Automated count

0.00

-0.00

0.0

1.1

—

13.43

—

(3002619) Bacteria identified in Specimen by Culture

0.00

-0.00

0.0

1.2

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

6.82

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

-0.00

0.0

1.0

—

(3032185) JC virus DNA [#/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

7.6

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.0

—

1.10

—

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

-0.00

0.0

2.4

—

6.08

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.0

—

(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

-0.00

0.0

1.5

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT – Disorders related to long gestation and high birth weight

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Disorders related to long gestation and high birth weight

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints