No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
458 |
4. Check minimum number of eventsNone |
458 |
5. Include endpointsNone |
458 |
6. Filter based on genotype QC (FinnGen only) |
418 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Thyrotropin deficiency
based on the number of shared cases.
Similar with more cases:
- Hypopituitarism
- Exclusions for E4_PCOS_BROAD
- Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT
- Disorders of other endocrine glands
- Exclusions for E4_PCOS_CONSORTIUM
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 418 | 307 | 111 |
| Unadjusted period prevalence (%) | 0.09 | 0.11 | 0.05 |
| Median age at first event (years) | 51.49 | 48.78 | 58.98 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 430
- Matched controls
- 4300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E23.05
ICD-10 Finland
Lack of TSH
+∞
307.7
430
*
H03AA01
ATC
levothyroxine sodium; systemic
112.0
299.2
411
696
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
147.7
265.6
133
13
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
158.5
233.5
116
10
H02AB09
ATC
hydrocortisone; systemic
47.3
211.6
130
39
E23.00
ICD-10 Finland
Panhypopituitarism
477.3
81.9
79
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
6.8
80.3
173
386
101
Kela drug reimbursment
Anterior pituitary hypofunction
122.5
75.9
80
8
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
12.5
68.1
72
68
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
25.8
58.9
42
18
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
141.7
58.5
61
5
E03.89
ICD-10 Finland
Other specified hypothyroidism
9.4
51.4
66
81
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
244.4
43.8
44
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
8.2
38.2
54
74
E22.1
ICD-10 Finland
Hyperprolactinaemia
75.8
31.4
35
5
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
+∞
30.6
29
*
E23.03
ICD-10 Finland
Lack of ACTH
166.6
30.1
31
*
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
10.7
29.5
33
33
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.7
28.6
110
362
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.2
28.2
86
240
N04BC06
ATC
cabergoline; oral
53.5
25.6
30
6
N06AX16
ATC
venlafaxine; oral
3.2
22.9
115
442
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
84.6
21.9
24
*
XCK00
NOMESCO Finland
Perimetry
5.1
21.8
49
106
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
231.3
21.8
22
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.1
20.6
37
65
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.2
20.2
58
153
N05AH04
ATC
quetiapine; oral
2.8
19.2
122
530
H01AC01
ATC
somatropin; parenteral
46.2
18.4
22
5
ZXC86
NOMESCO Finland
Use of endoscopic device
46.2
18.4
22
5
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.2
18.0
80
283
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
17.8
17
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.7
17.6
60
179
N06AX21
ATC
duloxetine; oral
2.9
16.9
91
359
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.7
16.7
112
496
N91.1
ICD-10 Finland
Secondary amenorrhoea
7.5
15.8
23
32
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.5
15.8
23
32
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.2
15.8
71
252
E23.2
ICD-10 Finland
Diabetes insipidus
88.4
15.7
17
*
E23.06
ICD-10 Finland
Empty sella
165.8
15.6
16
*
N05BA04
ATC
oxazepam; oral
2.3
14.7
150
802
N06AB10
ATC
escitalopram; oral
2.4
14.6
136
699
N06AX12
ATC
bupropion; oral
3.2
14.3
61
209
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.5
14.3
52
161
N03AF02
ATC
oxcarbazepine; oral
4.9
14.0
32
70
102
Kela drug reimbursment
Diabetes insipidus
77.7
13.7
15
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
77.7
13.7
15
*
D35.31
ICD-10 Finland
Cyst in Rathke's pocket
77.7
13.7
15
*
N06AX26
ATC
vortioxetine; oral
3.2
13.5
59
205
N06AX11
ATC
mirtazapine; oral
2.2
13.4
181
1077
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.8
13.3
31
69
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.9
13.1
67
255
G47.3
ICD-10 Finland
Sleep apnoea
2.3
12.9
123
634
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.9
12.5
38
104
R53
ICD-10 Finland
Malaise and fatigue
2.2
12.4
142
787
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
38.8
12.3
15
*
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
10.1
11.9
23
24
E66.01
ICD-10 Finland
Obesity due to excess calories
2.7
11.8
71
294
H53.4
ICD-10 Finland
Visual field defects
5.7
11.8
22
40
N06AB04
ATC
citalopram; systemic
2.3
11.7
112
575
E23.08
ICD-10 Finland
Hypopituitarism
+∞
11.5
11
*
SPAT1249
SPAT
Treatment-related counselling outside office
2.0
11.2
189
1202
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.4
11.0
28
67
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.3
10.9
42
135
R06.0
ICD-10 Finland
Dyspnoea
2.1
10.9
133
751
CS494
NOMESCO Finland
Other visual field testing
5.8
10.8
20
36
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
8.3
10.7
23
29
SPAT1252
SPAT
Overall medication plan or its review
3.6
10.5
36
107
AA1AD
NOMESCO Finland
CT of head and brain
2.1
10.5
124
690
N06AX22
ATC
agomelatine; oral
4.7
10.4
24
53
T86
ICPC
Hypothyroidism/myxoedema
3.6
10.2
34
99
E03
ICD-10 Finland
Other hypothyroidism
3.1
10.1
44
152
R51.80
ICD-10 Finland
Headache
2.2
10.1
101
525
301
Kela drug reimbursment
Growth hormone
41.1
10.0
12
*
E66.8
ICD-10 Finland
Other obesity
3.1
10.0
43
148
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.4
10.0
25
59
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
9.9
131
757
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
18.0
9.5
14
8
E23
ICD-10 Finland
Hypofunction and other disorders of pituitary gland
+∞
9.4
9
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.6
9.4
32
95
N03AX09
ATC
lamotrigine; oral
3.1
9.3
41
143
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
9.1
48
185
SPAT1243
SPAT
Psychiatric/psychological examination
4.2
9.1
24
59
H47.2
ICD-10 Finland
Optic atrophy
24.6
9.0
12
5
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
8.9
103
564
G02CB01
ATC
bromocriptine; systemic
4.8
8.9
20
43
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
8.9
139
848
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
8.9
62
275
N03AE01
ATC
clonazepam; systemic
3.3
8.7
34
110
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.0
8.6
25
66
SPAT1234
SPAT
Support of social functional capacity
4.0
8.6
25
66
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.4
8.6
67
313
C02AC05
ATC
moxonidine; oral
4.5
8.5
21
49
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.2
8.4
34
113
2273A
ICD-9 Finland
Benign neoplasm of other endocrine glands and related structures, Pituitary gland and craniopharyngeal duct (pouch)
+∞
8.4
8
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
8.4
109
623
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
11.1
8.4
15
14
N05AF03
ATC
chlorprothixene; systemic
4.4
8.3
21
50
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.7
8.2
46
183
P76
ICPC
Depressive disorder
2.6
8.2
50
208
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
8.2
32
104
N05AH03
ATC
olanzapine; systemic
2.8
8.1
42
160
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
8.1
126
763
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
8.0
71
349
SPAT1240
SPAT
Therapeutic discussion
2.3
8.0
66
315
N03AX12
ATC
[U] gabapentin; oral
2.1
8.0
83
435
IGY02, ,
SPAT
6.8
8.0
19
29
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
7.9
140
884
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.2
7.8
31
102
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.4
7.7
57
259
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
7.7
58
266
SPAT1153
SPAT
Removal of sutures
1.9
7.7
131
816
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.0
7.6
35
125
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
7.6
139
886
SPAT1216
SPAT
Assessment of functional ability
2.3
7.6
63
302
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
7.6
200
1421
N05CF02
ATC
zolpidem; oral
2.0
7.4
92
514
N05BA01
ATC
diazepam; systemic, rectal
2.2
7.4
64
311
N05BA12
ATC
alprazolam; oral
2.4
7.4
54
244
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
7.0
7.4
17
25
F50.9
ICD-10 Finland
Eating disorder, unspecified
11.1
7.3
13
12
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
9.6
7.3
14
15
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
4.4
7.3
18
42
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
7.3
181
1260
N06AB03
ATC
fluoxetine; oral
2.2
7.3
66
328
N30.0
ICD-10 Finland
Acute cystitis
2.0
7.1
87
483
N06AX03
ATC
mianserin; oral
3.2
7.1
28
91
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.1
7.1
29
97
G44.2
ICD-10 Finland
Tension-type headache
2.0
7.0
80
434
A02BC02
ATC
pantoprazole; systemic
1.8
7.0
291
2329
SPAT1307
SPAT
Psychosocial counselling and guidance
2.7
7.0
39
155
A46
ICD-10 Finland
Erysipelas
2.2
6.9
60
292
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
6.9
60
293
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
6.8
188
1340
L28
ICPC
Limited function/disability (L)
2.0
6.7
76
410
SPAT1262
SPAT
Handing over of treatment supplies
2.1
6.7
69
360
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
3.5
6.6
23
69
N06AB06
ATC
sertraline; oral
2.1
6.6
70
370
SPAT1263
SPAT
Sampling
1.7
6.5
180
1279
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.1
6.5
65
335
N05AX12
ATC
aripiprazole; systemic
3.0
6.5
29
102
N02AA05
ATC
oxycodone; systemic
2.0
6.5
71
379
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
7.6
6.5
14
19
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
70.9
6.4
7
*
E23.6
ICD-10 Finland
Other disorders of pituitary gland
70.9
6.4
7
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
6.4
93
547
E86
ICD-10 Finland
Volume depletion
6.7
6.4
15
23
SPAT1312
SPAT
General health counselling
1.7
6.4
141
942
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
11.2
6.3
11
10
SPAT1301
SPAT
No procedures
1.8
6.3
132
868
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.4
6.3
44
195
XA800
NOMESCO Finland
Neuropsychological investigation
2.9
6.3
29
104
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
18.3
6.3
9
5
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
6.3
114
719
N05CD07
ATC
temazepam; oral
2.4
6.3
45
202
R50.9
ICD-10 Finland
Fever, unspecified
2.0
6.3
72
391
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
6.3
166
1165
P03
ICPC
Feeling depressed
2.1
6.2
63
327
R42
ICD-10 Finland
Dizziness and giddiness
1.9
6.1
95
570
-, ,
ICD-10 Finland
4.2
6.1
16
39
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.0
6.1
67
357
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
6.1
54
265
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
3.0
6.1
26
89
C03CA01
ATC
furosemide; systemic
1.9
6.1
93
556
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
6.0
144
980
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.0
6.0
74
411
N06AG02
ATC
moclobemide; oral
3.2
6.0
24
79
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
321
399
28.79
281.65
5.3
1.9
351.48
379.81
nmol/l
1.45
307
382
200
198
18.01
193.84
3.6
1.5
419.84
287.14
mu/l
3.66
191
178
229
280
16.36
193.66
4.3
3.9
4.20
4.62
pmol/l
5.39
217
249
101
40
32.69
149.18
2.1
1.4
29.09
28.82
ng/l
0.01
101
40
112
63
23.69
143.97
2.8
1.3
386.72
305.96
mu/l
0.96
105
49
150
158
14.04
136.20
1.8
1.3
9.51
10.70
u/l
0.36
130
129
78
92
10.14
63.04
1.8
1.4
16.53
25.03
u/l
1.46
73
77
72
101
8.36
50.31
1.8
1.4
0.46
0.40
nmol/l
0.24
55
78
113
265
5.43
47.39
5.7
2.3
11.20
12.84
nmol/l
1.20
104
253
112
321
4.37
35.96
2.0
1.3
19.56
23.99
iu/l
0.86
102
277
267
1537
2.94
25.87
5.5
4.7
35.83
36.49
g/l
1.23
256
1467
269
1574
2.89
24.93
7.5
6.2
1.21
1.22
mmol/l
1.22
259
1470
284
1751
2.83
23.09
8.2
7.0
1.21
1.21
mmol/l
0.16
248
1525
100
356
3.36
22.59
1.2
1.3
31.13
157.52
u/ml
7.70
42
148
423
3606
11.63
21.59
12.5
5.6
0.86
1.81
mu/l
71.32
400
3395
313
2137
2.71
18.99
6.0
4.8
6.31
6.50
mmol/l
1.31
300
1990
107
437
2.93
18.82
5.3
6.6
104.82
104.45
mmol/l
0.34
107
437
197
1104
2.45
18.10
5.4
3.7
0.00
0.00
estimate
0.80
79
409
50
130
4.22
17.71
1.7
2.0
1.93
4.67
iu/l
1.82
19
53
179
969
2.45
17.66
3.0
2.1
2.76
2.73
mg/l
0.10
165
844
205
1254
2.21
14.45
3.5
3.1
2.34
2.35
mmol/l
1.36
191
1152
71
270
2.95
13.95
5.2
3.8
1.23
1.23
mmol/l
0.02
66
236
89
383
2.67
13.84
10.1
5.9
—
—
—
0
0
257
1743
2.18
13.68
3.4
2.6
78.27
76.25
nmol/l
0.58
245
1605
362
2862
2.67
12.96
9.6
7.6
78.32
77.20
u/l
0.19
351
2735
102
484
2.45
12.88
2.9
2.4
23.35
22.85
%
0.15
92
452
115
578
2.35
12.76
2.9
2.3
13.51
13.73
umol/l
0.12
108
536
182
1103
2.13
12.72
2.4
2.1
149.68
187.00
u/l
0.74
172
1054
234
1562
2.09
12.60
5.0
3.4
0.00
0.02
estimate
0.96
70
363
133
715
2.25
12.56
2.0
1.6
72727721.79
18810741.56
pmol/l
0.48
121
622
93
429
2.49
12.45
5.5
5.8
1.05
1.04
mmol/l
0.20
93
397
131
706
2.23
12.26
2.7
2.5
2.42
2.44
mmol/l
0.57
116
638
107
531
2.35
12.16
3.0
2.3
2.42
2.38
g/l
0.24
99
490
189
1184
2.06
11.89
3.6
2.5
54.11
65.11
u/l
1.06
175
1106
360
2878
2.54
11.87
5.3
4.3
10.08
10.31
mm/h
0.15
340
2711
80
351
2.57
11.86
4.5
9.2
0.62
0.79
mmol/l
0.21
61
300
300
2226
2.15
11.85
10.7
9.7
3.98
4.04
e9/l
0.21
275
1943
282
2046
2.10
11.80
4.4
3.1
90.94
91.59
ug/l
0.03
272
1938
277
2026
2.03
10.96
5.3
3.6
0.00
0.00
estimate
0.50
83
426
281
2067
2.04
10.93
5.3
3.7
0.08
0.00
estimate
0.49
83
405
200
1318
1.97
10.57
4.2
3.4
30.94
79.46
ng/l
0.47
130
805
277
2048
1.99
10.36
5.3
3.6
0.00
7.25
estimate
0.80
84
432
225
1561
1.93
10.05
2.3
2.0
97.92
97.81
pmol/l
0.01
137
817
265
1957
1.92
9.62
7.1
6.0
9.45
10.49
umol/l
0.86
251
1863
146
893
1.96
9.35
2.8
3.1
2309.48
844.72
ng/l
0.46
116
753
99
527
2.14
9.27
1.9
1.6
1636.90
1185.63
nmol/l
3.23
85
406
213
1503
1.83
8.55
11.5
10.0
1.10
1.15
inr
0.98
191
1229
157
1011
1.87
8.44
1.9
1.6
20.65
20.97
nmol/l
0.09
144
863
400
3510
3.00
8.40
7.7
5.7
38.54
38.46
mmol/mol
0.06
390
3349
130
793
1.92
8.23
3.1
2.6
6.50
7.56
e6/l
0.30
121
716
106
604
2.00
8.18
3.0
3.3
0.82
0.82
mmol/l
0.08
101
583
52
224
2.50
7.92
7.4
7.5
24.75
24.63
mmol/l
0.09
52
224
17
23
7.65
7.74
1.2
1.4
—
—
—
0
0
14
14
10.29
7.58
2.8
1.5
217.93
90.79
nmol/24h
0.70
14
14
172
1180
1.76
7.27
3.7
3.0
34.15
109.33
e6/l
0.68
149
877
95
547
1.95
7.02
1.9
1.9
—
—
—
0
0
17
40
4.38
6.81
1.8
1.7
89.46
91.37
%
0.80
17
40
404
3635
2.84
6.70
19.6
12.7
87.11
86.92
ml/min/173m2
0.06
389
3328
138
910
1.76
6.57
5.3
3.5
1.02
1.02
kg/l
0.34
90
597
402
3615
2.72
6.55
6.5
4.6
5.80
5.83
mmol/l
0.14
390
3394
72
389
2.02
6.35
1.9
1.8
—
—
—
0
0
28
98
2.99
6.33
1.2
1.2
—
—
—
0
0
23
72
3.32
6.24
3.6
2.8
6.47
8.07
pmol/l
0.48
23
72
156
1080
1.70
6.17
1.4
1.3
0.78
1.92
u/ml
1.54
63
325
72
402
1.95
5.77
1.9
1.8
—
—
—
0
0
17
46
3.81
5.70
1.2
1.3
0.15
0.18
nmol/l
0.92
12
32
12
16
7.68
5.67
1.3
1.1
156.42
175.98
mmol/24h
0.34
12
16
48
233
2.19
5.58
2.2
2.2
3.16
7.64
ug/l
2.42
43
211
413
3809
3.13
5.55
20.4
13.5
17.85
21.27
mg/l
2.17
359
3063
146
1017
1.66
5.52
3.3
2.9
0.28
0.31
e6/l
0.11
120
713
57
301
2.03
5.33
5.8
3.8
2.19
1.67
mmol/l
0.67
48
258
40
184
2.29
5.28
3.4
3.2
2.84
1.76
mmol/l
1.25
25
132
21
70
3.10
5.17
5.4
2.4
5.08
4.95
kpa
0.35
21
70
166
1212
1.60
5.12
3.7
3.2
8.34
7.84
mmol/l
0.62
148
1050
39
181
2.27
5.05
1.4
1.5
—
—
—
0
0
229
1821
1.55
4.77
3.0
2.7
—
—
estimate
—
0
0
47
241
2.07
4.76
1.7
1.6
—
—
—
0
0
15
43
3.58
4.65
1.2
1.6
—
—
—
0
0
158
1172
1.55
4.41
3.8
3.1
0.00
0.02
estimate
1.15
67
345
130
924
1.58
4.37
2.4
2.6
321.93
325.02
umol/l
0.15
115
827
40
200
2.10
4.34
6.4
3.6
131.30
132.09
g/l
0.08
40
195
17
57
3.06
4.17
1.4
1.6
—
—
—
0
0
16
52
3.16
4.12
1.8
1.3
419.56
422.80
pmol/l
0.01
16
46
48
267
1.90
3.89
2.9
3.6
109.07
78.56
ng/l
0.40
40
241
12
28
4.38
3.84
1.2
1.6
—
—
—
0
0
35
175
2.09
3.81
1.3
1.4
—
—
—
0
0
36
182
2.07
3.81
6.0
3.0
0.56
0.60
%
0.40
36
182
16
55
2.98
3.77
1.4
1.4
—
—
—
0
0
36
185
2.03
3.65
6.2
3.0
1.03
1.23
%
0.96
36
185
37
193
2.00
3.61
2.2
1.4
0.25
0.26
mg/l
0.05
11
80
8
14
5.80
3.35
1.6
1.4
—
—
—
0
0
43
244
1.85
3.29
2.0
2.1
4331.99
5286.29
u/l
0.08
14
101
313
2766
1.48
3.26
4.4
3.3
43.83
43.98
u/l
0.01
299
2646
22
97
2.34
3.25
1.5
1.5
—
—
—
0
0
174
1392
1.42
3.09
4.2
3.1
29.17
29.58
u/l
0.10
162
1326
123
923
1.47
3.08
2.3
2.1
—
—
—
0
0
21
95
2.27
2.95
1.3
1.5
—
—
—
0
0
81
562
1.54
2.94
2.1
1.7
1.41
1.37
%
0.28
75
506
9
23
3.97
2.79
3.0
2.4
—
—
—
0
0
5
6
8.41
2.75
1.2
1.0
—
—
—
0
0
13
48
2.76
2.74
1.3
1.3
—
—
—
0
0
13
48
2.76
2.74
1.2
1.5
—
—
—
0
0
198
1651
1.37
2.64
2.1
1.9
1.65
1.37
mmol/l
2.97
173
1446
21
100
2.16
2.63
1.9
1.4
13.50
13.56
e6/l
0.00
16
73
139
1095
1.40
2.61
4.6
4.1
8.03
9.54
mg/mmol
0.16
91
687
380
3552
1.60
2.54
5.2
4.1
1.45
1.25
mmol/l
5.04
369
3335
400
3795
1.77
2.42
6.6
5.4
2.70
2.80
mmol/l
1.59
388
3591
116
898
1.40
2.39
1.7
1.7
0.61
1.13
mg/l
2.75
97
695
71
504
1.49
2.32
1.8
2.0
28.39
29.17
s
1.01
71
490
22
113
2.00
2.30
1.5
1.4
358.09
318.29
ug/g
0.36
11
64
425
4150
3.07
2.19
34.3
21.0
4.50
4.51
e12/l
0.23
420
4078
111
865
1.38
2.19
1.4
1.3
12.55
29.65
iu/ml
4.62
24
264
394
3742
1.63
2.12
5.9
4.7
1.40
1.50
mmol/l
5.60
382
3534
26
146
1.83
2.11
1.5
1.2
—
2.04
—
0
8
395
3756
1.63
2.09
6.2
4.8
4.58
4.75
mmol/l
3.15
384
3563
45
297
1.58
2.05
1.3
1.5
—
—
—
0
0
304
2772
1.33
1.94
3.4
3.5
—
—
—
0
0
80
602
1.40
1.93
2.9
2.5
1.11
0.90
e6/l
0.27
51
298
7
22
3.22
1.88
2.4
3.0
3.29
1.41
%
—
7
22
24
137
1.80
1.87
1.5
1.3
—
12.54
—
0
26
5
12
4.20
1.83
1.2
1.1
—
—
—
0
0
94
734
1.36
1.82
6.7
4.8
1.51
2.25
ug/l
0.97
86
662
74
556
1.40
1.80
3.1
2.7
5.65
3.02
e6/l
0.66
45
252
44
299
1.53
1.79
2.1
2.3
72.25
73.19
ml/min/173m2
0.06
24
131
41
275
1.54
1.77
1.6
1.3
58.74
31.90
au/ml
—
5
23
28
174
1.65
1.65
1.8
1.6
—
—
—
0
0
8
32
2.53
1.60
1.5
1.7
—
—
—
0
0
30
192
1.60
1.59
7.8
3.7
24.18
24.25
mmol/l
0.05
30
192
99
797
1.31
1.56
1.4
1.3
5.30
8.57
u/ml
0.35
41
330
19
108
1.79
1.53
1.5
1.3
—
1.17
—
0
7
9
37
2.46
1.48
1.0
1.2
139.22
107.11
pmol/l
—
9
37
49
356
1.42
1.46
6.0
3.2
—
—
—
0
0
17
95
1.82
1.45
4.1
1.6
—
—
—
0
0
12
59
2.06
1.45
2.5
2.8
—
1327.40
—
0
5
20
118
1.73
1.44
1.8
2.8
7.58
11.24
mg/l
1.73
20
113
15
81
1.88
1.42
1.5
3.8
1.18
2.33
ratio
—
6
41
6
23
2.63
1.37
1.2
1.5
—
—
—
0
0
5
17
2.96
1.36
1.2
1.2
—
—
—
0
0
22
137
1.64
1.32
1.4
1.3
—
—
—
0
0
13
69
1.91
1.30
1.9
1.8
—
—
—
0
0
5
18
2.80
1.29
1.2
2.5
76.12
77.31
ug/l
—
5
18
25
163
1.57
1.26
1.6
1.7
—
—
—
0
0
55
420
1.35
1.25
2.2
2.0
—
—
—
0
0
11
201
0.54
1.24
1.4
1.5
1.11
0.97
ratio
—
6
129
11
201
0.54
1.24
1.4
1.5
1.03
1.08
ratio
—
6
129
11
201
0.54
1.24
1.4
1.5
0.82
1.21
ratio
—
6
129
9
45
2.02
1.24
1.6
1.2
—
—
—
0
0
11
200
0.54
1.22
1.4
1.5
—
—
—
0
0
6
26
2.33
1.19
1.7
1.8
—
—
—
0
0
8
38
2.13
1.19
1.6
1.3
—
—
—
0
0
20
126
1.62
1.16
2.0
1.7
—
—
—
0
0
45
337
1.37
1.16
1.9
1.9
—
—
—
0
0
8
39
2.07
1.16
1.1
1.2
—
—
—
0
0
74
597
1.29
1.16
5.1
4.1
19.07
21.39
%
0.73
39
259
5
20
2.52
1.15
1.2
1.3
—
—
—
0
0
20
127
1.60
1.13
1.4
1.3
—
—
—
0
0
8
40
2.02
1.12
1.1
1.2
—
—
—
0
0
24
160
1.53
1.12
3.0
1.6
1.21
1.19
g/l
0.16
24
155
5
21
2.40
1.09
1.2
1.6
—
—
—
0
0
15
89
1.71
1.09
1.8
1.5
—
—
—
0
0
5
22
2.29
1.03
1.2
1.6
—
—
—
0
0
5
22
2.29
1.03
2.0
3.7
350.80
868.27
mg
—
5
22
5
22
2.29
1.03
1.4
1.1
—
—
—
0
0
14
83
1.71
1.02
1.3
1.3
—
—
—
0
0
11
61
1.82
0.99
1.0
1.1
2.17
11.94
iu/ml
—
6
16
5
23
2.19
0.98
1.6
1.3
110.10
168.88
pmol/l
—
5
23
9
52
1.75
0.93
1.3
1.2
—
—
—
0
0
13
205
0.62
0.89
1.4
2.0
3.04
2.83
mg/l
—
8
153
6
31
1.95
0.84
1.7
2.0
—
—
—
0
0
76
642
1.22
0.83
2.1
2.0
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
7.21
—
0
24
25
336
0.73
0.79
1.6
1.6
745.70
988.48
mu/l
0.87
20
274
30
390
0.75
0.76
1.5
1.8
3.46
3.50
mmol/l
0.08
23
291
110
971
1.18
0.75
1.9
1.7
—
—
—
0
0
5
24
2.10
0.74
9.4
9.1
13.04
587.74
ug/l
—
5
19
5
24
2.10
0.74
1.2
1.6
—
—
—
0
0
54
445
1.24
0.74
1.9
2.3
4.18
6.38
umol/l
2.62
47
390
11
68
1.63
0.72
1.6
1.4
—
—
—
0
0
5
26
1.93
0.71
1.4
1.0
2097.60
1645.65
miu/ml
—
5
26
42
516
0.79
0.71
1.6
2.0
3.41
3.43
ratio
0.07
33
415
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
12
79
1.53
0.63
2.0
1.6
—
—
—
0
0
10
65
1.55
0.56
1.3
1.9
—
—
—
0
0
6
37
1.63
0.55
2.7
2.4
104.50
106.49
mmol/l
—
6
37
6
40
1.51
0.52
1.8
1.1
—
72.20
—
0
5
11
75
1.48
0.51
2.0
1.5
—
—
—
0
0
9
65
1.39
0.51
1.4
1.1
—
—
—
0
0
16
119
1.36
0.49
1.1
1.9
—
—
—
0
0
16
119
1.36
0.49
1.3
1.1
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
—
—
—
0
0
16
120
1.35
0.47
1.3
1.1
—
—
—
0
0
78
699
1.14
0.46
2.2
2.2
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
15
0.00
0.41
0.0
1.0
—
131.93
—
0
15
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
106.27
—
0
11
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
7.1
—
35.80
—
0
5
8
61
1.32
0.39
1.8
1.6
—
—
—
0
0
5
35
1.43
0.39
1.0
1.3
—
—
—
0
0
5
37
1.36
0.37
1.8
1.5
—
—
—
0
0
5
37
1.36
0.37
3.0
2.4
1.21
1.19
mmol/l
—
5
37
48
423
1.15
0.37
4.5
4.4
31.10
32.06
%
0.24
41
301
14
108
1.31
0.35
1.3
1.5
53.45
51.43
ug/l
0.06
14
108
15
117
1.29
0.35
1.3
1.8
—
—
—
0
0
6
45
1.34
0.34
1.7
1.4
—
—
—
0
0
6
45
1.34
0.34
1.7
1.4
—
—
—
0
0
6
45
1.34
0.34
1.2
1.1
—
—
—
0
0
23
192
1.21
0.33
1.4
1.7
—
—
—
0
0
28
243
1.16
0.27
1.4
1.4
—
—
—
0
0
50
454
1.11
0.26
3.4
2.9
0.57
0.72
ug/l
1.44
36
275
29
330
0.87
0.26
3.1
4.2
83.84
21.11
ug/l
0.34
21
265
15
123
1.23
0.25
1.3
1.3
66.08
191.97
pmol/l
0.75
15
118
5
39
1.29
0.23
1.4
1.4
—
—
—
0
0
5
40
1.25
0.22
26.6
16.8
938.00
874.02
nmol/l
—
5
40
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
9.93
—
0
14
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
18
155
1.17
0.20
2.1
1.9
—
—
—
0
0
91
863
1.07
0.20
1.6
1.5
—
—
—
0
0
11
91
1.21
0.17
1.5
2.6
0.67
2.10
index
—
6
48
17
148
1.15
0.17
1.5
1.6
—
—
—
0
0
13
112
1.17
0.14
1.2
2.1
0.33
0.53
g/l
0.19
13
104
12
103
1.17
0.14
1.2
1.9
0.00
0.00
g/l
-0.00
12
96
5
44
1.14
0.10
1.8
1.4
—
—
—
0
0
5
47
1.06
0.09
2.6
1.4
—
—
—
0
0
5
47
1.06
0.09
2.6
1.4
—
—
—
0
0
5
47
1.06
0.09
2.4
1.4
—
—
—
0
0
5
64
0.78
0.08
1.0
1.3
—
—
—
0
0
5
64
0.78
0.08
1.0
1.3
—
—
—
0
0
7
68
1.03
0.08
1.0
1.5
—
—
—
0
0
8
93
0.86
0.07
1.3
1.6
—
—
—
0
0
22
233
0.94
0.06
1.8
1.5
—
—
—
0
0
19
179
1.06
0.05
1.2
1.1
0.85
0.90
g/l
0.39
19
179
13
138
0.94
0.02
1.5
1.3
—
—
—
0
0
26
252
1.03
0.02
1.2
1.0
—
—
—
0
0
67
662
1.01
0.01
3.0
3.8
51.66
299.39
ng/l
2.43
43
458
10
94
1.07
0.01
2.6
2.9
—
—
—
0
0
18
174
1.04
0.00
1.2
1.1
1.66
1.56
g/l
0.78
18
174
10
95
1.05
0.00
1.5
1.2
—
—
—
0
0
10
102
0.98
0.00
1.2
1.9
0.00
0.00
g/l
—
10
91
0
8
0.00
0.00
0.0
2.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
37.20
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
104.71
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: E4_THYROTROPIN_DEFICIENCY – Thyrotropin deficiency
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).