Sleep terrors [night terrors]

F5_SLEEPTERRORS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — F51.4 Cause of death: ICD-10 — F51.4 2 out of 7 registries used, show all original rules.	93
4. Check minimum number of events None	93
5. Include endpoints None	93
6. Filter based on genotype QC (FinnGen only)	80

Control definitions (FinnGen only)

Control exclude: F5_SLEEP

Extra metadata

First used in FinnGen datafreeze: DF5

NAME	F5_SLEEPTERRORS
CONTROL_EXCLUDE	F5_SLEEP
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	F514
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	F514
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Sleep terrors [night terrors] based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1681	662	1017
Only index persons	1307	520	787
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.03
Only index persons	0.03	0.02	0.03
Median age at first event (years)
Whole population	6.64	6.09	6.94
Only index persons	7.71	7.32	7.97

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	80	62	18
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	17.80	20.26	9.36

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
87: Matched controls
870

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

F51.4

ICD-10 Finland

Sleep terrors [night terrors]

+∞

125.3

F51.0

ICD-10 Finland

Nonorganic insomnia

+∞

32.3

IAB13

NOMESCO Finland

Psychiatric sleep disorder consultation

+∞

13.9

G47.9

ICD-10 Finland

Sleep disorder, unspecified

20.7

11.8

F51.9

ICD-10 Finland

Nonorganic sleep disorder, unspecified

29.8

11.6

F51.3

ICD-10 Finland

Sleepwalking [somnambulism]

+∞

9.5

IEY18

NOMESCO Finland

Psychiatric sleep coaching, individual

+∞

9.5

Z01.8

ICD-10 Finland

Other specified special examinations

4.0

7.3

IBB02

NOMESCO Finland

Psychiatric evaluation of working capacity and rehabilitation

+∞

6.3

N06AX11

ATC

mirtazapine; oral

3.2

6.2

138

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(44816559) Phosphatidylethanol [Mass/volume] in Blood

4.16

5.66

2.0

1.5

0.05

0.24

mg/l

—

(3019150) Specific gravity of Urine by Refractometry

187

2.70

4.74

5.2

2.7

1.02

kg/l

0.26

113

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

4.68

4.69

1.7

1.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

283

2.55

4.41

2.8

2.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

205

2.52

4.16

6.5

3.1

—

(3011288) Drugs identified in Urine by Screen method Nominal

3.01

3.86

3.4

2.6

—

(36304419) Bacteria [Presence] in Urine

173

2.46

3.78

6.3

2.9

—

estimate

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

182

2.43

3.72

2.3

2.0

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

102

2.71

3.69

3.5

3.0

1.06

0.59

e6/l

—

(3018418) pH of Serum or Plasma

139

2.50

3.58

3.6

3.4

7.40

7.39

0.79

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

303

2.30

3.56

3.4

2.7

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.64

3.42

3.3

3.2

2.56

4.01

e6/l

—

(3015736) pH of Urine

307

2.26

3.41

4.6

2.9

6.37

6.36

0.03

157

(3007853) Bacteria identified in Skin by Aerobe culture

2.77

3.23

1.9

—

(3030467) Casts [#/volume] in Urine by Automated count

176

2.29

3.22

6.7

3.0

0.09

0.25

e6/l

0.90

129

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

218

2.21

3.15

2.8

1.9

97.16

89.15

pmol/l

0.62

125

(3002582) Erythrocytes [#/volume] in Urine

205

2.18

3.00

6.4

3.0

22.23

61.51

e6/l

0.71

154

(42870588) Differential panel, method unspecified - Blood

241

2.12

2.90

5.2

7.4

—

(3018095) Leukocytes [#/volume] in Urine

259

2.10

2.87

7.0

3.7

26.70

52.16

e6/l

0.64

164

(3011397) Hemoglobin [Presence] in Urine by Test strip

187

2.13

2.72

5.1

3.1

—

(3031040) Bacteria [#/volume] in Urine by Automated count

487

2.19

2.64

6.5

4.1

—

203.33

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.42

2.63

1.5

3.1

15.86

493.81

ng/l

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

242

2.01

2.54

9.3

9.9

1.21

1.22

mmol/l

0.16

206

(40761535) Cells panel - Urine sediment

3.16

2.52

4.1

3.6

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.58

2.48

1.5

1.6

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

122

2.20

2.46

1.4

1.3

12.60

7.89

u/ml

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

185

2.05

2.46

2.1

2.2

2.21

2.43

mg/l

0.34

158

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

4.38

2.41

1.0

1.2

—

(40768797) Stomach Pathology biopsy report

2.71

2.41

1.5

1.1

—

(40758558) Short blood count panel - Blood

222

1.96

2.33

6.6

5.5

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

231

1.95

2.31

4.7

3.3

23.31

27.84

u/l

1.39

223

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

2.92

2.31

1.5

1.3

—

(3035350) Ketones [Presence] in Urine by Test strip

378

1.93

2.30

5.8

3.4

0.00

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

379

1.92

2.27

6.0

3.5

0.00

estimate

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

323

1.90

2.24

2.9

1.9

—

(3000850) Epithelial cells [#/volume] in Urine

142

2.07

2.24

6.2

2.3

10.36

8.84

e6/l

0.23

127

(3001019) Free T4 and TSH panel - Serum or Plasma

3.22

2.22

1.6

2.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

3.91

2.20

2.3

1.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

210

1.92

2.14

2.8

2.1

—

(40768804) Tissue Pathology biopsy report

228

1.90

2.12

1.6

1.7

—

(3016879) Cocaine [Presence] in Urine

107

2.13

2.08

2.6

2.0

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

171

1.94

2.04

4.6

2.8

49.14

54.40

u/l

0.57

161

(3000764) Benzodiazepines [Presence] in Urine

116

2.07

2.01

2.6

2.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.38

2.01

1.6

—

(44790049) Parainfluenza type 3 nucleic acid detection

4.75

1.97

1.0

1.2

—

(44806118) Parainfluenza type 4 nucleic acid detection

4.75

1.97

1.0

1.2

—

(44790047) Parainfluenza type 1 nucleic acid detection

4.75

1.97

1.0

1.2

—

(44790048) Parainfluenza type 2 nucleic acid detection

4.75

1.97

1.0

1.2

—

(3027008) Opiates [Presence] in Urine

117

2.05

1.96

2.6

2.0

—

(3028300) Cannabinoids [Presence] in Urine

117

2.05

1.96

2.7

2.0

—

(3027944) Amphetamines [Presence] in Urine

118

2.03

1.92

2.6

2.0

—

(3022621) pH of Urine by Test strip

2.47

1.90

5.1

1.9

6.00

6.24

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

3.71

1.87

1.0

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

376

1.78

1.83

5.9

3.4

0.00

estimate

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

738

2.93

1.82

17.1

10.5

65.30

65.55

umol/l

0.06

724

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

145

1.90

1.78

4.3

2.4

9.32

12.56

ng/l

0.73

(1002224) Polysomnography panel

3.08

1.76

1.0

1.1

—

(3019060) Gas panel - Arterial blood

3.31

1.69

12.5

31.2

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

132

1.89

1.66

1.4

1.3

53.10

13.56

iu/ml

—

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

2.12

1.66

1.8

1.6

—

(3026008) Bacteria identified in Urine by Culture

226

1.74

1.63

3.5

2.2

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

2.00

1.61

2.9

2.2

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

150

1.83

1.60

1.9

2.5

0.60

1.49

mg/l

1.05

105

(3048689) Calprotectin [Mass/mass] in Stool

150

1.83

1.60

3.4

2.6

23.91

67.78

ug/g

2.63

104

(3036481) Cortisol [Moles/volume] in Serum or Plasma

2.06

1.56

1.7

2.1

346.60

370.79

nmol/l

0.20

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

2.73

1.55

1.7

1.8

—

4.01

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

2.59

1.53

1.8

1.9

—

(3025941) Bacteria identified in Stool by Culture

2.52

1.51

1.1

1.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.46

1.48

1.3

1.1

—

(3023368) Bacteria identified in Blood by Culture

129

1.83

1.47

4.9

3.7

—

(3001604) Monocytes [#/volume] in Blood

372

1.65

1.46

5.5

6.8

0.54

0.53

e9/l

0.07

318

(3037467) Urinalysis macro (dipstick) panel - Urine

503

1.71

1.46

7.1

4.0

—

(3044290) Cell count panel - Cerebral spinal fluid

3.25

1.46

1.2

3.5

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

353

1.64

1.45

5.7

6.8

5.92

6.34

mmol/l

0.74

310

(3006315) Basophils [#/volume] in Blood

373

1.64

1.44

5.6

6.8

0.04

e9/l

0.11

319

(3045414) Leukocytes [Presence] in Urine

2.07

1.42

1.9

1.8

0.00

estimate

—

(3019198) Lymphocytes [#/volume] in Blood

394

1.63

1.40

5.4

6.7

1.97

2.07

e9/l

0.43

349

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

704

2.04

1.37

4.3

4.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.91

1.36

1.6

1.7

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

2.88

1.30

1.4

3.2

3.34

3.55

mmol/l

—

(3042936) Bacteria identified in Isolate by Culture

1.95

1.30

1.6

2.8

—

(3007566) Smooth muscle Ab [Titer] in Serum

2.50

1.26

1.2

1.6

—

94.29

—

(40761511) CBC panel - Blood by Automated count

760

2.37

1.23

14.0

8.7

—

(3013512) EKG study

121

1.73

1.18

3.2

2.9

—

(3013115) Eosinophils [#/volume] in Blood

386

1.54

1.16

6.4

7.9

0.14

0.17

e9/l

1.60

340

(3020779) Urea [Moles/volume] in Serum or Plasma

2.05

1.12

5.0

12.0

5.12

6.83

mmol/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

408

1.53

1.12

9.6

9.9

4.16

3.85

e9/l

0.40

348

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

2.29

1.11

2.1

5.1

3.89

3.24

g/l

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

606

1.67

1.11

13.2

7.8

104.55

102.58

ml/min/173m2

0.33

506

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.46

1.10

1.0

1.2

—

(3021589) Normoblasts [#/volume] in Blood

351

1.51

1.08

8.3

9.4

0.00

e9/l

0.50

277

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.06

1.07

2.8

4.3

—

(3028707) Methadone [Presence] in Urine by Screen method

2.00

1.06

3.5

2.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.35

1.05

1.0

1.2

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

2.35

1.05

1.4

2.9

433.80

315.32

mg/l

—

(3022145) Colonoscopy Study observation

1.92

0.96

1.5

1.4

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

1.97

0.96

1.9

4.4

260.57

163.35

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.85

0.95

1.3

1.4

—

(3000494) Fungus identified in Specimen by Culture

1.73

0.94

1.6

1.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

174

1.52

0.90

1.8

1.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.81

0.85

5.1

2.4

—

(3044640) Blood type and Crossmatch panel - Blood

203

1.48

0.85

2.3

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.80

0.0

1.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.80

0.0

2.0

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.80

0.0

1.1

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

367

1.40

0.79

2.9

2.3

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.24

0.77

1.0

1.3

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.64

0.77

5.8

7.0

0.79

0.80

mmol/l

0.20

(3029937) Albumin [Presence] in Urine by Test strip

199

1.44

0.74

7.3

3.3

0.00

0.01

estimate

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

1.77

0.72

1.6

4.1

107.14

96.73

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.77

0.72

1.9

1.7

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.98

0.72

6.4

17.3

97.46

94.36

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

1.98

0.72

1.8

1.0

—

(3034770) Mitochondria Ab [Titer] in Serum

1.98

0.72

1.4

1.6

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

148

1.46

0.67

2.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

316

1.36

0.67

3.5

3.1

—

estimate

—

(3007164) IgA [Mass/volume] in Serum or Plasma

259

1.37

0.66

1.5

2.00

1.97

g/l

0.06

144

(3012516) Albumin [Mass/volume] in Urine

124

1.46

0.61

5.1

4.0

141.31

50.63

mg/l

—

(3020682) Albumin/Creatinine [Ratio] in Urine

124

1.46

0.61

5.4

4.6

20.89

10.62

mg/mmol

—

(3000991) Gas panel - Venous blood

1.56

0.60

12.4

13.0

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.60

0.0

2.1

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.71

0.58

6.2

1.4

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.71

0.58

1.7

1.5

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.54

0.58

8.3

8.9

1.06

1.15

mmol/l

0.94

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.56

0.56

1.3

1.6

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.53

0.54

1.1

1.0

—

(3000492) Spirometry study

1.45

0.53

1.1

1.3

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

730

1.48

0.48

17.7

10.2

19.95

21.17

mg/l

0.14

548

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

292

1.27

0.44

1.5

0.90

1.21

u/ml

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

105

1.40

0.44

2.5

2.4

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.65

0.44

1.4

1.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

160

1.32

0.44

1.6

1.5

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.44

0.43

6.6

12.5

22.31

24.88

mmol/l

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

1.55

0.42

1.4

1.0

0.49

6.11

u/ml

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.55

0.42

1.2

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.41

0.0

1.1

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.3

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.4

—

(3035933) Granulocytes/Leukocytes in Blood

0.00

0.40

0.0

2.3

—

52.62

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

1.50

0.37

2.3

1.4

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.42

0.36

1.3

1.4

—

(3008898) HLA-B27 [Presence]

1.39

0.35

1.0

1.1

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.32

0.31

1.9

3.8

4.25

5.17

pmol/l

—

(3019832) Treponema pallidum Ab [Presence] in Serum

294

1.20

0.29

2.1

2.0

—

(3020961) Endomysium IgA Ab [Titer] in Serum

1.25

0.28

1.1

1.3

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.28

0.27

1.0

1.3

—

(1761868) Lipid panel - Serum or Plasma

271

0.84

0.24

2.3

2.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

182

1.20

0.24

2.3

4.1

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3035715) Granulocytes [#/volume] in Blood

0.00

0.21

0.0

2.7

—

3.42

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3014599) Egg white IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

0.26

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

1.27

0.21

1.3

1.1

9.10

3.42

u/ml

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

1.17

0.19

1.2

1.3

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.72

0.17

1.4

1.9

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.74

0.16

1.2

1.8

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

170

0.86

0.15

1.6

1.7

953.23

900.15

mu/l

—

145

(3017732) Neutrophils [#/volume] in Blood

0.83

0.14

3.1

3.3

4.12

3.78

e9/l

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.12

0.09

5.7

13.2

105.17

104.50

mmol/l

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

107

1.14

0.09

1.6

2.98

3.20

ratio

—

(40761536) Microorganisms panel - Urine sediment

0.77

0.08

5.4

3.1

—

(3003694) ABO and Rh group [Type] in Blood

285

1.08

0.08

2.2

2.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

1.11

0.08

1.9

1.6

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

1.09

0.08

1.9

1.8

—

(21494755) Public health laboratory ask at order entry panel

1.04

0.07

1.2

1.3

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

1.04

0.07

1.8

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

292

0.94

0.05

2.0

1.9

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.09

0.02

1.3

1.5

—

(36660697) Celiac disease serology panel - Serum

104

1.07

0.01

1.5

1.1

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

205

0.97

0.00

1.8

1.7

—

(3050129) First trimester maternal screen panel - Serum or Plasma

114

0.96

0.00

1.3

1.6

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

0.98

0.00

11.2

9.6

24.94

24.39

mmol/l

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.1

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

11.4

—

0.57

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

1.02

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

4.2

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.2

—

11.33

—

(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3049717) Cytology report of Urine Cyto stain

0.00

-0.00

0.0

1.4

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.3

—

(3004809) Band form neutrophils/Leukocytes in Blood

0.00

-0.00

0.0

2.5

—

0.67

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

44.40

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.85

-0.00

1.4

1.7

66.79

49.49

ug/l

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.0

—

(3025378) Microscopic observation [Identifier] in Cervix by Cyto stain

0.00

-0.00

0.0

1.0

—

(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

58.33

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3021788) Differential panel - Synovial fluid

0.00

-0.00

0.0

1.4

—

(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3002256) Pathology report gross observation

1.00

-0.00

1.0

1.1

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.0

—

(40759040) C peptide [Moles/volume] in Serum or Plasma --post meal

0.00

-0.00

0.0

1.0

—

2.12

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

6.84

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

8.07

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.7

—

19.00

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1633.50

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

1.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.1

—

(3022411) Androstenedione [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

7.40

—

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(44806420) Estimation of glomerular filtration rate

0.00

-0.00

0.0

1.8

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

4.1

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

124.25

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint F5_SLEEPTERRORS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_SLEEPTERRORS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: F5_SLEEPTERRORS – Sleep terrors [night terrors]

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Sleep terrors [night terrors]

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints