No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
394 |
4. Check minimum number of eventsNone |
394 |
5. Include endpointsNone |
394 |
6. Filter based on genotype QC (FinnGen only) |
312 |
Control definitions (FinnGen only)
- Control exclude
- AB1_HIV
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Unspecified human immunodeficiency virus [HIV] disease
based on the number of shared cases.
Similar with more cases:
- Unspecified human immunodeficiency virus [HIV] disease, including avohilmo
- Human immunodeficiency virus [HIV] disease
- Human immunodeficiency virus [HIV] disease, including avohilmo
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2230 | 539 | 1557 |
| Only index persons | 1747 | 492 | 1255 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.04 |
| Only index persons | 0.04 | 0.02 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 39.14 | 34.60 | 41.16 |
| Only index persons | 39.53 | 34.14 | 41.64 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 312 | 51 | 261 |
| Unadjusted period prevalence (%) | 0.10 | 0.02 | 0.12 |
| Median age at first event (years) | 42.21 | 40.78 | 42.49 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 375
- Matched controls
- 3750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
+∞
307.7
370
*
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
+∞
307.7
324
*
WW200
NOMESCO Finland
Immunization
323.0
307.7
296
43
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
37.4
289.5
232
156
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
150.4
134
*
Z25.1
ICD-10 Finland
Need for immunization against influenza
19.5
127.5
111
79
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
+∞
124.0
112
*
Z3231
NOMESCO Finland
Registered nurse
9.7
109.9
243
597
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
8.8
71.2
106
160
Z2221
NOMESCO Finland
Medical doctor
5.0
53.2
183
596
B18.2
ICD-10 Finland
Chronic viral hepatitis C
14.2
44.2
42
33
A63.0
ICD-10 Finland
Anogenital (venereal) warts
8.7
40.1
55
73
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
7.4
39.4
63
100
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.7
38.6
83
177
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
38.2
36
*
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
136.4
35.4
37
*
A51.0
ICD-10 Finland
Primary genital syphilis
356.8
33.4
33
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
31.4
239
1236
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
4.4
26.1
77
210
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.9
24.5
87
271
K02.9
ICD-10 Finland
Dental caries, unspecified
10.4
24.4
28
29
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
+∞
24.2
23
*
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
133.5
23.9
25
*
C10AA07
ATC
rosuvastatin; oral
3.0
23.4
181
899
A51.9
ICD-10 Finland
Early syphilis, unspecified
+∞
23.2
22
*
A53.9
ICD-10 Finland
Syphilis, unspecified
+∞
22.1
21
*
Y25
ICPC
Fear sexually transm disease male
6.2
21.6
39
69
N05CD07
ATC
temazepam; oral
4.6
21.6
57
142
A54.5
ICD-10 Finland
Gonococcal pharyngitis
116.5
20.8
22
*
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
5.8
20.4
39
73
B20.6
ICD-10 Finland
HIV disease resulting in Pneumocystis jirovecii pneumonia
+∞
18.9
18
*
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
5.0
18.0
41
90
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
99.8
17.7
19
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
5.9
17.3
32
58
J05AB01
ATC
aciclovir; systemic
2.9
17.0
100
418
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.9
16.8
31
56
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.6
16.7
42
100
QAJ99
NOMESCO Finland
Other aesthetic operations on skin of head or neck
+∞
15.7
15
*
ULA02
NOMESCO Finland
Kolposcopy
4.5
15.0
39
95
TAB00
NOMESCO Finland
Lumbar puncture
4.6
14.9
37
87
WX110, ,
SPAT
4.0
14.3
44
122
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
10.7
14.2
27
27
N05CF01
ATC
zopiclone; oral
2.4
14.2
134
699
Z3226
NOMESCO Finland
Physiotherapist
2.8
13.8
83
347
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.6
13.8
49
150
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.4
13.8
129
669
Z01.2
ICD-10 Finland
Dental examination
2.3
13.7
204
1289
F43.29
ICD-10 Finland
Adaptation disorder UNS
5.5
13.6
27
52
B90
ICPC
HIV-infection/AIDS
+∞
13.6
13
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.6
13.4
97
446
R50.9
ICD-10 Finland
Fever, unspecified
2.7
13.1
85
369
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
72.4
12.7
14
*
B20.9
ICD-10 Finland
HIV disease resulting in unspecified infectious or parasitic disease
+∞
12.6
12
*
O98.5
ICD-10 Finland
Other viral diseases complicating pregnancy, childbirth and the puerperium
134.3
12.5
13
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.8
12.0
71
293
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
11.7
116
611
EB1AA, ,
SPAT
3.5
11.6
43
135
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.3
11.6
110
568
N06AB04
ATC
citalopram; systemic
2.5
11.5
89
419
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
13.3
11.3
19
15
R4110
NOMESCO Finland
Physiotherapy
2.2
11.2
122
666
ZXD35
NOMESCO Finland
Usual procedure
5.1
11.1
24
50
A01AB04
ATC
amphotericin B; local oral
5.8
10.8
20
36
Z71.8
ICD-10 Finland
Other specified counselling
2.1
10.7
144
852
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
+∞
10.5
10
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
+∞
10.5
10
*
Y71
ICPC
Gonorrhoea male
+∞
10.5
10
*
K05.31
ICD-10 Finland
Periodontitis pronounced
2.7
10.4
63
263
K02.2
ICD-10 Finland
Caries of cementum
4.1
10.0
28
72
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
26.8
9.9
13
5
TLC00
NOMESCO Finland
Insertion of intrauterine device
4.3
9.9
26
64
UJH02
NOMESCO Finland
Anoscopy
4.4
9.8
25
60
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
8.2
9.8
21
27
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.7
9.7
32
93
WYA30, ,
SPAT
15.6
9.6
15
10
B02.9
ICD-10 Finland
Zoster without complication
3.6
9.6
32
94
B20.0
ICD-10 Finland
HIV disease resulting in mycobacterial infection
+∞
9.4
9
*
P19
ICPC
Drug abuse
11.1
9.4
17
16
J01MA12
ATC
levofloxacin; systemic
2.3
9.3
79
385
UJF30
NOMESCO Finland
Ileoscopy through colon
2.8
9.2
50
197
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.9
8.8
45
171
D06BB10
ATC
imiquimod; topical
3.9
8.8
26
70
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.9
8.8
26
70
N05BA01
ATC
diazepam; systemic, rectal
2.5
8.7
59
260
D11
ICPC
Diarrhoea
2.5
8.7
59
260
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.7
8.4
27
77
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
8.4
96
527
0788B
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Other specified diseases due to viruses and Chlamydiae[HIV-INFEKTIO,OIREISET TAUDINKUVAT]
+∞
8.4
8
*
0788C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Other specified diseases due to viruses and Chlamydiae[AIDS, IMMUUNIKATO]
+∞
8.4
8
*
B20.3
ICD-10 Finland
HIV disease resulting in other viral infections
+∞
8.4
8
*
B20.1
ICD-10 Finland
HIV disease resulting in other bacterial infections
+∞
8.4
8
*
A55
ICD-10 Finland
Chlamydial lymphogranuloma (venereum)
+∞
8.4
8
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
14.9
8.3
13
9
SAA04
NOMESCO Finland
Special examination of mouth
3.5
8.3
29
88
Z2446
NOMESCO Finland
Social worker
3.1
8.2
35
120
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.9
8.2
41
154
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.4
8.1
63
294
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
10.4
8.1
15
15
ZX114
NOMESCO Finland
Intramuscular
9.7
7.8
15
16
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.5
7.8
27
81
TGC00
NOMESCO Finland
Bronchial lavation
4.7
7.7
18
40
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
7.7
66
322
C10AA03
ATC
pravastatin; oral
3.6
7.7
26
77
C10AA01
ATC
simvastatin; oral
0.4
7.5
31
758
F15.5
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, psychotic disorder
13.7
7.4
12
9
Z3232
NOMESCO Finland
Midwife
3.1
7.4
31
105
N06AA12
ATC
doxepin; systemic
3.6
7.4
24
69
N05BA04
ATC
oxazepam; oral
2.0
7.4
97
558
Y70
ICPC
Syphilis male
+∞
7.3
7
*
B21.3
ICD-10 Finland
HIV disease resulting in other malignant neoplasms of lymphoid, haematopoietic and related tissue
+∞
7.3
7
*
A52.9
ICD-10 Finland
Late syphilis, unspecified
+∞
7.3
7
*
B23
ICD-10 Finland
Human immunodeficiency virus [HIV] disease resulting in other conditions
+∞
7.3
7
*
B20.7
ICD-10 Finland
HIV disease resulting in multiple infections
+∞
7.3
7
*
B20.4
ICD-10 Finland
HIV disease resulting in candidiasis
+∞
7.3
7
*
OAB43, ,
SPAT
0.5
7.2
76
1282
TQW99
NOMESCO Finland
Other minor procedure on skin
3.8
7.1
22
61
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.7
7.1
40
160
S02.51
ICD-10 Finland
Fracture of tooth, open
2.4
7.0
48
212
N06AX11
ATC
mirtazapine; oral
1.8
6.9
133
864
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
2.1
6.9
77
416
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
6.8
125
799
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.4
6.8
25
78
-1, ,
NOMESCO Finland
1.8
6.7
136
898
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
2.3
6.6
50
231
J05AB11
ATC
valaciclovir; oral
2.2
6.5
58
287
N07BA03
ATC
varenicline; oral
2.8
6.5
34
131
B59
ICD-10 Finland
Pneumocystosis
71.0
6.4
7
*
A52.1
ICD-10 Finland
Symptomatic neurosyphilis
71.0
6.4
7
*
3044A
ICD-9 Finland
Drug dependence, Amphetamine and other psychostimulant dependence
71.0
6.4
7
*
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
8.4
6.4
13
16
ZXE00
NOMESCO Finland
One hour or less
1.8
6.3
134
892
D07AA02
ATC
hydrocortisone; topical
2.2
6.3
59
298
A51.5
ICD-10 Finland
Early syphilis, latent
+∞
6.3
6
*
B22.0
ICD-10 Finland
HIV disease resulting in encephalopathy
+∞
6.3
6
*
B16.9
ICD-10 Finland
Acute hepatitis B without delta-agent and without hepatic coma
+∞
6.3
6
*
0788A
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Other specified diseases due to viruses and Chlamydiae[HIV-PRIMAARI-INFEKTIO JA OIREETON KANTAJAVAIHE]
+∞
6.3
6
*
A23
ICPC
Risk factor NOS
2.3
6.2
48
223
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.1
6.2
17
43
TLC02
NOMESCO Finland
Simple extraction of IUD
6.5
6.2
15
24
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
5.9
6.2
16
28
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
12.8
6.1
10
8
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
359
435
170.99
307.65
17.3
7.7
0.92
1.01
mmol/l
7.45
359
418
364
16
7722.59
307.65
19.1
1.3
905.08
—
u/ml
—
231
0
337
94
344.92
307.65
9.1
4.5
145.21
443.09
mg/l
1.42
327
47
293
16
833.89
307.65
3.8
3.0
31.05
36.73
%
0.83
70
11
338
21
1622.14
307.65
3.4
1.8
31.84
36.90
%
0.76
338
21
257
311
24.08
226.75
2.7
3.3
29.25
46.68
u/l
0.65
252
262
75
22
42.36
121.14
3.4
2.4
14.72
16.55
%
0.33
75
22
370
1661
92.97
112.44
14.2
7.8
11.47
12.55
umol/l
1.10
370
1599
320
1088
14.24
105.34
7.3
3.8
64.60
93.78
e6/l
0.24
167
778
53
10
61.56
94.07
3.6
1.4
—
—
—
0
0
365
1561
51.18
93.22
22.5
6.9
50.54
57.42
%
35.55
365
1513
72
40
22.04
92.08
1.1
1.1
—
—
—
0
0
365
1596
49.26
89.98
22.9
7.0
35.94
27.61
%
50.88
365
1535
54
20
31.37
80.48
5.5
2.6
—
—
—
0
0
108
152
9.57
77.23
5.6
2.0
—
—
—
0
0
52
24
24.99
71.39
5.2
2.4
983.02
712.63
e6/l
0.78
47
19
347
1643
15.89
71.30
6.2
3.1
0.00
0.00
estimate
-0.00
44
332
348
1663
16.18
70.49
6.2
3.2
0.00
0.02
estimate
0.79
45
296
347
1661
15.59
69.89
6.2
3.2
0.00
5.30
estimate
0.50
46
330
109
179
8.17
67.80
5.8
2.1
—
—
—
0
0
87
113
9.72
65.78
1.2
1.3
199.70
243.74
miu/ml
0.34
27
52
217
815
4.95
52.39
4.0
3.0
0.26
0.43
e6/l
0.51
152
587
283
1444
4.91
42.46
2.5
1.9
1.46
1.53
mmol/l
0.52
274
1264
56
74
8.72
41.05
2.4
3.8
1.83
2.70
index
0.35
12
47
238
1103
4.17
40.02
5.1
3.7
9.21
9.11
mmol/l
0.10
232
963
143
472
4.28
38.87
3.4
2.9
2.42
1.21
e6/l
0.44
61
216
141
471
4.19
37.52
4.8
1.9
—
—
—
0
0
148
515
4.10
37.14
3.4
2.7
0.92
0.80
e6/l
0.21
66
257
132
426
4.24
36.73
4.5
1.9
—
—
—
0
0
38
39
10.73
33.53
2.3
1.8
—
—
—
0
0
54
103
5.96
27.92
2.5
1.6
—
—
—
0
0
37
47
8.62
27.75
2.1
2.6
45.10
41.18
iu/ml
—
7
5
55
130
4.79
22.21
1.6
1.6
1.22
1.60
g/l
2.09
49
120
369
3108
12.70
20.60
10.6
4.6
6.01
6.00
mmol/l
0.06
369
2933
74
241
3.58
19.24
2.6
2.4
77.70
70.67
ml/min/173m2
0.99
41
109
136
641
2.76
18.59
3.5
2.7
2.93
5.12
e6/l
0.95
131
588
47
114
4.57
18.30
1.2
1.7
0.02
0.11
iu/ml
0.68
22
18
51
139
4.09
17.04
1.4
1.4
—
—
—
0
0
30
52
6.18
16.92
1.2
1.4
—
—
—
0
0
30
52
6.18
16.92
1.2
1.4
—
—
—
0
0
23
35
6.94
14.64
4.7
3.3
—
—
—
0
0
36
91
4.27
13.23
1.2
1.6
152.38
146.17
au/ml
—
8
27
136
733
2.34
13.21
1.6
1.6
18.00
19.42
nmol/l
0.75
129
649
343
2808
3.60
12.05
34.7
17.8
13.34
13.45
%
1.00
343
2785
365
3121
7.36
11.98
10.5
5.8
36.23
39.06
mmol/mol
9.22
365
3001
370
3342
9.03
11.48
11.1
4.9
1.30
1.34
mmol/l
1.55
370
3187
34
93
3.92
11.23
1.8
9.3
7539.40
320.56
iu/ml
—
5
18
369
3345
7.44
10.59
11.3
5.0
4.47
4.67
mmol/l
5.04
369
3206
370
3364
8.49
10.55
11.5
5.4
2.76
2.82
mmol/l
0.89
370
3214
19
19
10.47
10.13
6.3
3.2
41.55
31.43
mu/l
0.47
19
19
20
28
7.48
8.85
1.2
1.0
—
—
—
0
0
14
10
14.48
8.76
1.8
1.0
—
—
iu/ml
—
0
0
364
3224
5.40
8.72
19.1
14.9
21.70
23.49
mg/l
0.53
304
2634
13
8
16.76
8.61
1.4
1.3
—
—
—
0
0
55
235
2.57
8.60
1.8
1.5
—
—
—
0
0
33
111
3.16
7.99
3.4
3.1
—
—
—
0
0
49
209
2.55
7.67
1.5
1.6
—
—
—
0
0
110
663
1.93
7.28
2.3
2.1
2.47
2.89
mg/l
1.21
101
587
39
156
2.67
6.94
1.7
1.7
—
—
—
0
0
65
349
2.04
5.89
2.1
1.9
—
—
—
0
0
63
342
2.01
5.53
2.2
1.9
—
—
—
0
0
35
156
2.37
5.00
1.9
1.3
—
—
—
0
0
140
1005
1.63
4.73
4.0
4.3
10.93
10.39
mg/mmol
0.06
95
681
23
86
2.78
4.67
1.3
2.4
63.93
107.17
mg/l
0.26
23
70
329
2936
1.98
4.62
35.1
17.6
336.70
335.37
g/l
1.88
329
2927
19
65
3.03
4.51
3.1
1.7
—
—
—
0
0
168
1274
1.58
4.45
2.2
2.6
72.19
71.15
nmol/l
0.16
162
1187
38
185
2.17
4.43
2.2
5.4
74.24
96.47
ng/l
1.21
38
176
56
318
1.89
4.30
3.2
4.0
0.19
1.90
mmol/l
1.82
44
282
22
86
2.66
4.13
1.3
2.4
52.58
53.08
mg/l
0.01
22
70
162
1237
1.55
4.06
2.0
1.9
98.87
96.94
pmol/l
0.28
107
707
21
81
2.69
4.04
1.2
2.1
1.10
1.21
ratio
—
9
42
74
468
1.72
3.99
2.1
2.0
—
—
—
0
0
7
234
0.29
3.74
1.0
1.1
1.02
0.92
g/l
—
7
234
11
25
4.50
3.65
1.7
3.0
—
—
—
0
0
7
229
0.29
3.60
1.0
1.1
1.55
1.44
g/l
—
7
229
17
63
2.78
3.54
2.4
1.6
—
—
—
0
0
6
6
10.13
3.51
3.5
1.7
—
—
—
0
0
21
88
2.47
3.46
1.2
1.1
—
—
—
0
0
85
582
1.60
3.35
3.1
3.7
36.99
587.70
ng/l
2.41
63
428
10
25
4.08
3.10
1.6
3.7
1218.70
1356.76
mg
—
10
25
13
45
2.96
3.05
1.2
1.4
—
—
—
0
0
109
1412
0.68
2.91
2.8
3.5
25.80
21.72
%
0.85
39
515
92
1231
0.67
2.90
3.0
3.3
22.61
37.36
ng/l
0.98
49
803
49
302
1.72
2.89
3.0
3.3
—
—
—
0
0
14
323
0.41
2.85
5.4
6.8
—
—
—
0
0
58
377
1.64
2.81
2.1
1.7
946.66
1186.14
nmol/l
1.55
53
307
176
1442
1.42
2.79
7.5
9.2
1.20
1.20
mmol/l
0.24
159
1273
20
91
2.27
2.79
1.1
1.4
—
—
—
0
0
20
91
2.27
2.79
1.2
1.1
—
—
—
0
0
41
244
1.76
2.74
1.7
1.8
0.35
0.35
mg/l
0.02
28
126
18
79
2.34
2.72
1.0
1.2
—
—
—
0
0
6
10
6.08
2.71
1.5
1.0
—
—
—
0
0
6
10
6.08
2.71
1.5
1.0
—
—
—
0
0
164
1351
1.38
2.42
10.8
12.4
1.19
1.19
inr
0.05
137
1130
148
1771
0.73
2.32
3.7
4.0
1.85
1.73
ug/l
0.09
140
1645
15
66
2.33
2.27
2.9
4.3
4.73
5.05
kpa
1.53
15
66
8
24
3.38
2.19
2.9
5.3
1.25
0.87
index
—
8
24
7
19
3.73
2.16
1.0
1.2
—
—
—
0
0
238
2637
0.73
2.15
4.8
3.7
63.67
53.85
u/l
0.80
225
2539
10
36
2.83
2.15
1.1
1.4
—
—
—
0
0
10
36
2.83
2.15
1.1
1.4
—
—
—
0
0
10
36
2.83
2.15
1.1
1.4
—
—
—
0
0
7
20
3.55
2.06
1.0
1.1
585.14
248.48
iu/ml
—
7
20
8
26
3.12
2.02
1.1
1.0
—
—
—
0
0
8
26
3.12
2.02
1.1
1.0
—
—
—
0
0
116
928
1.36
1.99
5.1
3.8
2.36
2.35
mmol/l
0.34
101
863
95
736
1.39
1.98
2.5
2.4
—
—
—
0
0
9
33
2.77
1.94
1.1
1.5
—
—
—
0
0
5
142
0.34
1.92
3.0
3.7
25.80
25.17
mmol/l
—
5
135
9
34
2.69
1.87
1.1
1.5
—
—
—
0
0
9
34
2.69
1.87
1.1
1.5
—
—
—
0
0
9
35
2.61
1.81
6.7
2.2
—
—
—
0
0
12
54
2.26
1.75
1.6
1.6
—
—
—
0
0
45
311
1.51
1.72
5.0
10.7
9.02
8.47
mmol/l
0.22
45
301
10
40
2.54
1.68
1.2
1.3
—
—
—
0
0
7
25
2.83
1.65
1.0
1.6
3.27
4.74
mg/l
—
7
25
10
44
2.31
1.56
1.1
1.3
—
—
—
0
0
82
645
1.35
1.55
2.2
2.2
1.66
1.51
%
1.29
69
573
5
15
3.36
1.53
4.8
2.3
—
—
—
0
0
6
21
2.89
1.51
1.0
1.3
—
—
—
0
0
8
166
0.47
1.51
4.4
3.6
52.75
52.59
%
—
8
161
94
759
1.32
1.48
1.3
1.3
2.22
1.30
u/ml
—
10
242
15
81
1.89
1.42
2.3
1.4
28.50
15.89
e6/l
—
10
56
17
96
1.81
1.41
1.1
1.3
219.38
227.61
u/ml
—
8
60
164
1431
1.26
1.40
2.8
3.0
214.09
158.16
ug/l
0.49
159
1376
7
29
2.44
1.40
1.4
1.7
—
—
—
0
0
8
162
0.48
1.39
2.0
1.6
—
—
—
0
0
6
23
2.63
1.37
1.2
1.0
—
—
—
0
0
5
17
2.97
1.36
1.0
1.2
—
—
—
0
0
73
576
1.33
1.35
2.8
4.3
0.82
0.82
mmol/l
0.07
66
554
16
91
1.79
1.31
5.1
4.2
39.44
36.58
umol/l
0.18
16
85
91
745
1.29
1.29
1.9
1.9
3.13
1.18
mg/l
0.52
70
586
8
36
2.25
1.25
1.1
1.2
—
—
—
0
0
13
71
1.86
1.21
1.4
1.5
—
—
—
0
0
8
38
2.13
1.19
1.1
1.2
—
—
—
0
0
74
903
0.78
1.17
2.2
2.8
347.24
359.08
umol/l
0.51
68
834
11
58
1.92
1.13
1.5
1.5
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
102
864
1.25
1.10
6.2
3.3
0.00
0.00
estimate
0.50
45
304
7
32
2.21
1.08
1.1
1.2
—
—
—
0
0
7
32
2.21
1.08
1.1
1.2
—
—
—
0
0
7
32
2.21
1.08
1.1
1.2
—
—
—
0
0
112
1291
0.81
1.07
5.9
3.0
0.00
0.00
estimate
-0.00
40
283
9
49
1.86
0.99
1.0
1.1
—
—
—
0
0
7
36
1.96
0.97
1.1
1.2
—
—
—
0
0
13
77
1.71
0.96
1.3
1.4
499.83
11641.87
e6/l
—
6
53
17
256
0.65
0.96
1.2
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
14
85
1.67
0.95
2.4
3.8
0.57
0.30
iu/ml
—
5
38
95
1098
0.82
0.91
2.4
2.6
0.71
0.66
ug/l
0.09
67
558
5
102
0.48
0.90
1.0
1.1
—
3.37
—
0
13
337
3261
1.33
0.90
20.6
17.2
3.94
3.99
mmol/l
3.09
331
3206
79
668
1.23
0.87
1.6
1.5
—
—
—
0
0
15
212
0.70
0.65
1.9
3.7
136.47
134.58
g/l
0.17
15
207
7
44
1.60
0.65
1.6
2.1
12.29
10.99
mmol/l
—
7
44
5
29
1.73
0.64
1.2
1.1
—
—
—
0
0
334
3253
1.24
0.63
19.3
17.1
139.07
139.69
mmol/l
5.37
329
3203
0
21
0.00
0.60
0.0
1.6
—
0.22
—
0
5
13
185
0.69
0.59
2.7
3.0
0.53
0.64
%
1.33
13
185
16
115
1.41
0.57
2.3
2.7
22.65
24.62
mmol/l
1.52
16
115
6
38
1.59
0.54
1.7
1.1
—
—
—
0
0
6
39
1.55
0.53
1.0
1.1
—
—
—
0
0
7
46
1.53
0.48
1.0
1.2
—
—
—
0
0
7
47
1.50
0.48
1.0
2.1
—
—
—
0
0
43
366
1.20
0.47
14.7
13.8
-1.06
1.03
mmol/l
2.26
34
315
36
301
1.22
0.47
1.9
2.1
49.81
36.79
nmol/l
1.40
36
296
71
791
0.87
0.44
2.7
3.4
785.46
842.00
ng/l
0.10
64
642
242
2325
1.12
0.44
3.2
3.7
13.91
14.58
pmol/l
4.56
230
2183
56
494
1.16
0.42
2.7
3.1
2.44
2.43
mmol/l
0.28
42
443
13
96
1.37
0.42
1.1
1.8
—
—
—
0
0
12
161
0.74
0.42
1.6
1.6
255.25
266.15
mu/l
0.13
12
153
0
15
0.00
0.41
0.0
1.0
—
44.67
—
0
15
0
17
0.00
0.40
0.0
3.0
—
56.47
—
0
17
52
588
0.87
0.40
1.4
1.3
36.48
28.93
iu/ml
0.16
12
169
0
18
0.00
0.40
0.0
1.0
—
26.82
—
0
11
0
18
0.00
0.40
0.0
1.0
—
673.55
—
0
11
0
18
0.00
0.40
0.0
1.6
—
66.08
—
0
18
0
19
0.00
0.39
0.0
2.8
—
0.95
—
0
19
0
19
0.00
0.39
0.0
1.1
—
0.48
—
0
19
11
80
1.39
0.39
1.0
1.2
—
63.72
—
0
9
5
37
1.36
0.37
1.2
1.2
—
—
—
0
0
5
37
1.36
0.37
1.0
2.1
—
—
—
0
0
12
90
1.34
0.36
1.1
1.2
—
—
—
0
0
13
99
1.32
0.36
1.1
1.3
—
8.99
—
0
13
13
99
1.32
0.36
1.1
1.2
—
3.11
—
0
10
242
2340
1.10
0.35
3.4
3.2
—
—
—
0
0
12
155
0.77
0.34
1.2
1.5
19.97
18.99
iu/l
—
6
125
6
89
0.67
0.33
1.3
1.8
—
—
—
0
0
53
476
1.13
0.32
13.1
10.0
104.92
104.26
mmol/l
0.46
53
476
10
76
1.32
0.28
2.0
3.0
9.00
8.31
kpa
—
10
76
8
65
1.24
0.27
1.5
1.5
154.60
171.20
pmol/l
—
8
65
23
198
1.17
0.25
1.1
1.2
136.20
111.16
u/ml
—
5
69
135
1412
0.93
0.25
2.8
2.8
—
—
estimate
—
0
0
48
523
0.91
0.23
1.4
1.3
4.26
8.29
u/ml
—
10
217
11
88
1.26
0.23
1.4
1.6
—
—
—
0
0
6
48
1.25
0.20
1.3
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
4.4
—
79.98
—
0
14
22
193
1.15
0.20
2.2
3.5
0.06
1.74
mmol/l
2.18
12
144
92
967
0.94
0.19
5.4
2.6
0.00
0.01
estimate
0.80
40
264
10
81
1.24
0.19
1.1
1.3
—
—
—
0
0
12
100
1.21
0.18
1.3
1.9
—
—
—
0
0
7
59
1.19
0.18
1.4
1.2
—
—
—
0
0
8
68
1.18
0.16
1.5
1.6
—
—
—
0
0
77
732
1.07
0.16
6.5
3.4
1.02
1.02
kg/l
0.92
57
467
5
45
1.11
0.10
1.0
1.7
—
—
—
0
0
24
223
1.08
0.09
2.5
3.6
4.80
5.17
kpa
2.42
24
217
5
61
0.82
0.08
1.6
4.0
8.32
9.46
pmol/l
—
5
61
7
65
1.08
0.08
1.1
2.2
—
—
—
0
0
55
530
1.04
0.08
1.6
1.7
417.18
46875429.22
pmol/l
0.80
49
480
7
67
1.05
0.08
1.6
1.2
98.14
115.66
%
—
7
62
13
118
1.11
0.07
1.2
1.3
—
—
—
0
0
17
183
0.93
0.06
1.2
1.5
11.69
5.55
u/l
—
9
150
285
2865
0.98
0.04
4.7
4.5
1.86
1.84
mu/l
0.09
277
2707
11
101
1.09
0.04
1.5
2.0
—
—
—
0
0
10
94
1.07
0.01
1.4
1.5
182.02
271.18
ug/g
—
10
53
16
158
1.01
0.00
1.1
1.0
—
—
—
0
0
25
248
1.01
0.00
2.1
2.1
247.68
226.28
pmol/l
0.58
25
236
10
97
1.03
0.00
1.5
1.8
—
—
—
0
0
7
73
0.96
0.00
1.6
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
9.30
—
0
8
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
62
0.97
0.00
1.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
1.25
—
0
9
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
39.89
—
0
9
0
9
0.00
-0.00
0.0
10.4
—
10.90
—
0
9
7
72
0.97
-0.00
1.4
1.3
50.74
25.79
u/l
—
7
64
0
6
0.00
-0.00
0.0
3.2
—
51.32
—
0
6
7
71
0.99
-0.00
1.1
1.1
—
1.96
—
0
6
5
58
0.86
-0.00
1.0
1.1
—
1.54
—
0
26
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
16
160
1.00
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.23
—
0
5
6
63
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
7
71
0.99
-0.00
1.6
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_HIV_NOS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_HIV_NOS | 3.161 [2.63, 3.81] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 201 out of 1214 males with AB1_HIV_NOS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_HIV_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.477% |
| 5 | No data | 3.193% |
| 10 | No data | 8.646% |
| 15 | No data | 14.951% |
| 20 | No data | 24.987% |
Relationships between endpoints
↥Index endpoint: AB1_HIV_NOS – Unspecified human immunodeficiency virus [HIV] disease
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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