No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
137 |
4. Check minimum number of eventsNone |
137 |
5. Include endpointsNone |
137 |
6. Filter based on genotype QC (FinnGen only) |
118 |
Control definitions (FinnGen only)
- Control exclude
- E4_METABOLIA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E87
- Name in latin
- Incrementum voluminis liquoris
Similar endpoints
↥List of similar endpoints to
Fluid overload
based on the number of shared cases.
Similar with more cases:
- Other disorders of fluid, electrolyte and acid-base balance
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 582 | 293 | 287 |
| Only index persons | 524 | 263 | 261 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 69.82 | 72.88 | 66.78 |
| Only index persons | 69.84 | 72.88 | 66.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 118 | 55 | 63 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 66.30 | 69.79 | 63.25 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 121
- Matched controls
- 1210
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E87.7
ICD-10 Finland
Fluid overload
+∞
174.7
121
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
34.0
79.5
60
34
C03CA01
ATC
furosemide; systemic
19.8
50.0
101
246
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
162.1
49.2
49
5
Z49.1
ICD-10 Finland
Extracorporeal dialysis
182.8
46.6
46
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
117.6
43.5
45
6
TK800
NOMESCO Finland
Hemodialysis
84.1
43.4
47
9
I50.9
ICD-10 Finland
Heart failure, unspecified
11.2
40.4
63
107
N18.8
ICD-10 Finland
Other chronic renal failure
101.9
38.9
41
6
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
10.4
35.9
55
90
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
14.2
34.2
36
35
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
121.5
33.8
35
*
B03XA02
ATC
darbepoetin alfa; parenteral
155.9
33.7
34
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
215.0
32.4
32
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
10.0
28.7
40
57
A12AA04
ATC
calcium carbonate; oral
82.3
28.5
31
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.9
28.2
55
115
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
343.8
27.9
27
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
7.5
26.9
57
129
XF600
NOMESCO Finland
Bloodpressure measurement
12.1
26.4
30
32
A10AC01
ATC
insulin (human); parenteral
10.7
26.1
33
41
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.6
24.4
68
197
GD1AA
NOMESCO Finland
Thorax X-ray examination
9.7
24.3
102
430
A11CC03
ATC
alfacalcidol; systemic
68.7
24.2
27
5
N17.9
ICD-10 Finland
Acute renal failure, unspecified
39.2
24.2
30
10
A10AE04
ATC
insulin glargine; parenteral
8.3
23.7
38
63
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
281.0
23.5
23
*
A46
ICD-10 Finland
Erysipelas
7.1
23.4
47
99
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
24.7
23.4
33
18
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
77.9
22.8
25
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
6.2
22.4
61
171
E87.5
ICD-10 Finland
Hyperkalaemia
266.1
22.4
22
*
SPAT1262
SPAT
Handing over of treatment supplies
6.4
22.1
52
127
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
7.4
21.6
39
73
M10.9
ICD-10 Finland
Gout, unspecified
9.8
21.4
28
36
127
Kela drug reimbursment
Transplant complication
133.1
21.3
22
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.9
21.3
42
86
N18.0
ICD-10 Finland
End-stage renal disease
251.5
21.3
21
*
A10AB05
ATC
insulin aspart; parenteral
8.5
21.2
32
49
D64.9
ICD-10 Finland
Anaemia, unspecified
7.2
20.8
38
72
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
70.2
20.7
23
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
9.0
20.0
28
39
M04AA01
ATC
allopurinol; systemic
6.4
19.9
43
96
103
Kela drug reimbursment
Diabetes, insulin-treated
5.5
19.8
63
199
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
83.8
19.4
21
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
22.3
19.4
28
16
L04AD02
ATC
tacrolimus; systemic
223.2
19.1
19
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
53.2
19.0
22
5
L04AA06
ATC
mycophenolic acid; systemic
53.2
19.0
22
5
SPAT1148
SPAT
Treatment of chronic ulcer or burn
6.0
18.9
44
105
V03AE01
ATC
polystyrene sulfonate; oral
62.8
18.6
21
*
JN3AD
NOMESCO Finland
Abdominal CT examination
6.2
18.5
40
89
WX204
NOMESCO Finland
Axillary plexus blockaced
21.3
18.4
27
16
Z94.0
ICD-10 Finland
Kidney transplant status
79.0
18.3
20
*
TPH07
NOMESCO Finland
Cathetrisation of artery
6.6
18.2
36
73
V03AE02
ATC
sevelamer; oral
+∞
18.2
17
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
8.7
18.2
26
37
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.8
17.7
33
63
I50.0
ICD-10 Finland
Congestive heart failure
7.8
17.6
28
45
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
59.3
17.6
20
*
N19
ICD-10 Finland
Unspecified kidney failure
20.6
17.0
25
15
137
Kela drug reimbursment
Uraemia requiring dialysis
195.9
16.9
17
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
7.6
16.7
27
44
205
Kela drug reimbursment
Chronic hypertension
4.8
16.5
59
199
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.8
16.5
62
218
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
6.2
16.4
34
72
ZXD05
NOMESCO Finland
Urgent procedure
4.7
16.2
59
202
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.7
16.0
62
222
Z49.2
ICD-10 Finland
Other dialysis
+∞
16.0
15
*
C07AB07
ATC
bisoprolol; oral
5.3
16.0
90
428
196
Kela drug reimbursment
Paricalcitol and cinacalcet
182.6
15.9
16
*
R50.9
ICD-10 Finland
Fever, unspecified
5.2
15.8
43
116
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
4.7
15.6
53
171
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
6.7
15.3
28
52
C08CA01
ATC
amlodipine; oral
4.6
15.2
78
341
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
91.5
15.0
16
*
ZXE00
NOMESCO Finland
One hour or less
4.4
14.8
70
287
S97
ICPC
Chronic ulcer skin
6.7
14.8
27
50
C08CA02
ATC
felodipine; oral
7.1
14.7
25
43
R06.0
ICD-10 Finland
Dyspnoea
4.4
14.5
59
216
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
34.8
14.3
18
6
WX408
NOMESCO Finland
General anesthesy, balanced
4.5
14.3
52
175
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
60.9
14.2
16
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
12.8
14.1
25
24
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
7.2
14.0
23
38
H05BX01
ATC
cinacalcet; oral
84.6
13.9
15
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
13.8
13
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
156.9
13.7
14
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
156.9
13.7
14
*
WX892
NOMESCO Finland
Monitored bed care
7.2
13.5
22
36
J01FF01
ATC
clindamycin; systemic
4.2
13.2
54
196
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
11.0
13.0
25
28
ZXE10
NOMESCO Finland
More than one and less than three hours
4.0
13.0
63
258
J01MA12
ATC
levofloxacin; systemic
4.3
12.9
46
151
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
+∞
12.7
12
*
3025
Kela drug reimbursment
Calcium carbonate
+∞
12.7
12
*
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
14.7
12.7
21
17
B05DA
ATC
Isotonic solutions
144.3
12.7
13
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
12.1
12.7
23
23
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
18.5
12.6
19
12
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.9
12.5
34
90
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
5.6
12.4
27
59
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.9
12.3
68
301
T90
ICPC
Diabetes non-insulin dependent
4.0
12.1
49
175
AA1AD
NOMESCO Finland
CT of head and brain
3.8
12.0
58
234
JN4AD
NOMESCO Finland
Body CT examination
4.8
11.9
32
84
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
72.1
11.9
13
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.4
11.8
38
115
B05DB
ATC
Hypertonic solutions
+∞
11.6
11
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
132.0
11.6
12
*
E86
ICD-10 Finland
Volume depletion
132.0
11.6
12
*
B01AA03
ATC
warfarin; systemic
4.2
11.6
40
127
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
6.3
11.3
21
39
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
48.1
11.2
13
*
C03DA01
ATC
spironolactone; oral
4.6
11.0
31
84
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
24.2
11.0
15
7
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.9
10.9
42
144
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.3
10.9
25
57
WX730
NOMESCO Finland
Conventional respirator
66.0
10.8
12
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
10.3
10.8
21
24
GD1AD
NOMESCO Finland
Thorax CT examination
6.3
10.8
20
37
KBV00
NOMESCO Finland
Insertion of stent into ureter
120.0
10.6
11
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
+∞
10.6
10
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.8
10.5
44
159
H02AB06
ATC
prednisolone; systemic
3.6
10.5
77
398
H02AB04
ATC
methylprednisolone; systemic
4.3
10.4
33
98
X59
ICD-10 Finland
Exposure to unspecified factor
3.9
10.3
39
131
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
16.5
10.3
16
11
A10AA02, ,
ATC
13.9
10.2
17
14
WZC00
NOMESCO Finland
Treatment plan or consultation
3.4
10.2
63
291
SPAT1222
SPAT
Counselling/guidance promoting independent living
4.0
10.2
37
121
L28
ICPC
Limited function/disability (L)
3.8
10.1
40
139
J01MA14
ATC
moxifloxacin; systemic
4.9
10.0
25
61
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.6
10.0
21
44
V03AE03
ATC
lanthanum carbonate; oral
59.9
9.8
11
*
T89
ICPC
Diabetes insulin dependent
10.0
9.7
19
22
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
14.0
9.7
16
13
A10AB01
ATC
insulin (human); parenteral
10.9
9.7
18
19
AN1
HP
Coronary angiography
5.0
9.6
23
54
PB1AC
NOMESCO Finland
Angiography of upper extremity with X-ray
108.1
9.6
10
*
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
108.1
9.6
10
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.7
9.5
38
132
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
9.5
9
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
9.5
9
*
OAB70
NOMESCO Finland
Guidance related to hydration
+∞
9.5
9
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
11.4
9.4
17
17
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
9.2
9.3
19
24
A41.9
ICD-10 Finland
Sepsis, unspecified
9.9
9.2
18
21
H04AA01
ATC
glucagon; nasal, parenteral
20.6
9.2
13
7
A10BA02
ATC
metformin; oral
3.3
9.1
50
212
A10AA01, ,
ATC
15.6
8.9
14
10
C07AB02
ATC
metoprolol; systemic
3.5
8.8
39
144
321
Kela drug reimbursment
Paricalcitol and cinacalcet
54.0
8.8
10
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.7
8.8
34
115
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
4.0
8.8
30
93
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
9.0
8.7
18
23
R4110
NOMESCO Finland
Physiotherapy
3.3
8.7
47
197
N02AA05
ATC
oxycodone; systemic
3.5
8.6
39
146
WX402
NOMESCO Finland
General anaesthesia
3.5
8.6
38
140
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
+∞
8.4
8
*
H3603, E103,
ICD-10 Finland
+∞
8.4
8
*
WX213
NOMESCO Finland
Lower leg blockade
+∞
8.4
8
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
9.2
8.4
17
21
B01AB10
ATC
tinzaparin; parenteral
4.1
8.4
27
80
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
10.1
8.3
16
18
ZXE20
NOMESCO Finland
More than three and less than five hours
3.9
8.3
29
91
C10AA05
ATC
atorvastatin; oral
3.0
8.3
69
368
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.3
8.2
42
169
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
36.0
8.2
10
*
A10AD01
ATC
insulin (human); parenteral
24.0
8.2
11
5
OAB43, ,
SPAT
0.0
8.1
*
214
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.6
8.0
32
110
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.6
8.0
21
53
A10BH05
ATC
linagliptin; oral
7.6
7.9
18
27
A10AE05
ATC
insulin detemir; parenteral
7.1
7.9
19
31
EBA10
NOMESCO Finland
Operative extraction of tooth
4.2
7.9
24
68
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
48.1
7.8
9
*
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
48.1
7.8
9
*
C02AC05
ATC
moxonidine; oral
9.9
7.8
15
17
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
7.8
40
161
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
20.0
7.8
11
6
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
27.0
7.7
10
*
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
27.0
7.7
10
*
ED1AA
NOMESCO Finland
Mandibular X-ray examination
27.0
7.7
10
*
A10BH01
ATC
sitagliptin; oral
4.1
7.6
23
65
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.9
7.5
62
324
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.9
7.5
18
42
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
85.1
7.5
8
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.3
7.5
21
56
E0000UV, ,
ATC
2.9
7.4
61
318
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
3.0
7.4
45
199
A02BC02
ATC
pantoprazole; systemic
3.5
7.4
97
650
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
17.1
7.4
11
7
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
7.4
7
*
SPAT1254
SPAT
Administration of medicine
3.5
7.3
30
105
Z49.0
ICD-10 Finland
Preparatory care for dialysis
21.6
7.3
10
5
I50.1
ICD-10 Finland
Left ventricular failure
6.6
7.3
18
31
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
6.6
7.3
18
31
KA1AE
NOMESCO Finland
Kidney ultrasound examination
13.2
7.3
12
10
C01DA14
ATC
isosorbide mononitrate; oral
3.7
7.2
26
83
SPAT1149
SPAT
Suture or treatment of traumatic wound
3.4
7.2
30
106
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.3
7.0
31
113
OAB50, ,
SPAT
4.2
7.0
20
54
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
3.0
6.9
40
172
M10.3
ICD-10 Finland
Gout due to impairment of renal function
42.5
6.8
8
*
R03BA02
ATC
budesonide; inhalant
3.2
6.8
32
121
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
3.3
6.8
30
109
ZX120
NOMESCO Finland
Intravenous
4.2
6.8
20
55
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
24.1
6.8
9
*
N17.8
ICD-10 Finland
Other acute renal failure
24.1
6.8
9
*
C10AA01
ATC
simvastatin; oral
2.7
6.8
60
322
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.9
6.7
16
26
A06AD11
ATC
lactulose; oral
3.4
6.6
28
99
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.5
6.6
17
42
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
6.6
33
130
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.7
6.5
23
72
A10BK01
ATC
dapagliflozin; oral
4.3
6.5
18
47
Z3226
NOMESCO Finland
Physiotherapist
3.3
6.5
29
106
L89
ICD-10 Finland
Decubitus ulcer and pressure area
15.4
6.5
10
7
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
15.4
6.5
10
7
R80
ICD-10 Finland
Isolated proteinuria
73.6
6.5
7
*
TK810
NOMESCO Finland
Hemofiltration
73.6
6.5
7
*
A10AE06
ATC
insulin degludec; parenteral
10.1
6.5
12
13
E66.00
ICD-10 Finland
Metabolic syndrome
6.0
6.4
17
32
XF404
NOMESCO Finland
Ambulatory ECG
4.2
6.4
18
48
SPAT1211
SPAT
Application of soft bandage
3.9
6.3
20
58
B03XA01
ATC
erythropoietin; parenteral
28.3
6.3
8
*
SPAT1094
SPAT
Continuous Positive Airway Pressure
+∞
6.3
6
*
TK823
NOMESCO Finland
Peritoneal permeability analysis
+∞
6.3
6
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
+∞
6.3
6
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.6
6.3
23
74
N05BA01
ATC
diazepam; systemic, rectal
3.6
6.3
23
74
WW500
NOMESCO Finland
Blood transfusion
6.2
6.3
16
29
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.2
6.3
16
29
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.7
6.3
49
245
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
13.5
6.2
10
8
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
10.9
6.2
11
11
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.6
6.2
17
34
A10BB12
ATC
glimepiride; oral
4.5
6.1
16
40
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
3.6
6.1
22
70
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.0
6.1
14
22
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.6
6.1
53
279
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.7
6.0
42
197
WX002
NOMESCO Finland
Sedation and analgesia
3.0
6.0
33
136
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
6.0
26
93
E000002, ,
ATC
4.1
6.0
18
50
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
16.0
6.0
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
17
38.69
64.27
19.5
2.4
26.45
8.45
pmol/l
5.10
43
17
41
16
38.25
61.39
14.3
2.4
4.99
4.84
kpa
0.39
41
16
44
22
30.86
60.22
7.9
2.4
14.06
15.63
%
1.15
44
22
53
49
18.47
53.42
17.8
6.8
23.59
25.14
mmol/l
1.87
53
49
40
26
22.49
48.28
7.3
3.6
8.01
7.92
kpa
0.10
40
26
41
35
17.21
42.61
6.6
3.0
23.84
24.32
mmol/l
0.22
41
35
61
100
11.29
40.28
10.2
3.5
—
—
—
0
0
50
64
12.61
39.83
10.0
2.8
2.31
1.84
mmol/l
0.32
39
52
34
32
14.39
32.86
2.6
1.5
—
—
—
0
0
52
89
9.49
32.37
41.8
3.4
1.18
1.22
mmol/l
3.02
52
77
41
53
11.19
31.89
9.8
3.5
23.78
24.76
mmol/l
0.94
41
53
70
178
7.96
29.87
4.4
1.9
—
—
—
0
0
31
34
11.91
26.84
2.6
1.4
—
—
—
0
0
80
255
7.31
26.35
3.9
2.1
3.28
2.95
mg/l
0.75
70
224
32
38
11.09
26.17
2.8
1.5
—
—
—
0
0
31
36
11.23
25.73
3.0
3.7
56.95
26.94
mg/l
1.16
13
31
31
36
11.23
25.73
3.0
3.7
65.68
33.87
mg/l
1.28
13
31
30
34
11.40
25.31
3.0
2.9
1.32
2.12
ratio
0.45
11
18
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
34
19
24.35
23.94
3.9
2.4
0.31
0.35
iu/ml
0.22
22
13
89
338
7.18
23.47
5.5
3.3
9445.54
1295.00
ng/l
3.74
81
290
45
92
7.20
23.06
2.3
2.9
0.19
0.20
g/l
0.42
40
85
45
94
7.03
22.53
14.6
3.3
2.39
2.60
mmol/l
0.13
40
81
105
497
9.41
20.82
49.2
7.0
1.17
1.21
mmol/l
4.44
89
425
79
293
5.89
20.65
12.7
3.0
0.66
0.41
e6/l
0.58
70
222
26
11
29.63
19.64
2.8
1.4
—
—
—
0
0
39
81
6.63
19.39
3.3
1.6
—
—
—
0
0
50
135
5.61
18.68
3.8
1.8
—
—
—
0
0
91
405
6.03
18.47
13.2
3.6
74.53
36.39
ng/l
1.56
83
304
50
138
5.47
18.15
3.9
1.7
—
—
—
0
0
27
20
17.00
17.01
2.2
1.3
258.75
234.22
u/ml
—
21
9
22
9
29.44
16.71
3.1
1.3
—
—
—
0
0
27
21
16.18
16.68
2.0
1.2
—
—
—
0
0
27
22
15.44
16.36
2.5
1.2
136.00
164.60
au/ml
—
5
5
26
20
16.20
16.11
2.8
1.6
—
—
—
0
0
27
23
14.76
16.06
2.7
1.2
—
—
—
0
0
23
14
19.93
15.51
3.0
1.2
—
—
—
0
0
78
343
4.59
15.06
7.2
2.9
65.89
67.10
u/l
0.03
71
314
53
176
4.58
14.92
3.1
1.7
1816.48
1174.93
nmol/l
1.62
39
131
29
58
6.26
14.70
1.9
1.5
—
—
—
0
0
76
332
4.47
14.70
13.8
3.6
62.28
5.82
mg/mmol
3.11
68
198
21
13
19.23
14.06
1.4
1.8
32.86
33.00
pg
0.03
21
13
58
224
4.05
12.98
2.5
1.6
1.17
1.34
mg/l
0.34
50
177
29
65
5.55
12.95
5.1
2.3
30.52
64.23
ml/min/173m2
3.78
21
22
16
5
36.47
12.93
2.4
1.0
—
—
—
0
0
17
8
24.40
12.41
1.5
1.4
—
—
—
0
0
16
6
30.36
12.40
2.4
1.2
—
—
—
0
0
38
113
4.44
12.05
9.8
11.3
1.20
1.28
mmol/l
0.03
27
97
16
7
26.05
11.92
2.4
1.3
—
—
—
0
0
43
142
4.15
11.84
10.3
6.0
101.23
103.70
mmol/l
1.75
43
142
24
51
5.62
11.28
7.1
2.2
1.78
1.31
%
0.89
24
51
24
52
5.51
11.03
7.1
2.1
0.61
0.67
%
0.39
24
52
15
7
24.16
10.99
1.5
1.4
97.27
28.43
u/l
—
15
7
21
24
10.34
10.82
2.1
1.3
—
—
—
0
0
10
0
+∞
10.57
9.6
0.0
—
—
—
0
0
10
0
+∞
10.57
2.4
0.0
1.00
—
g/l
—
10
0
67
317
3.50
10.53
10.1
3.0
0.00
0.00
estimate
-0.00
39
95
22
29
9.02
10.48
2.1
1.3
—
—
—
0
0
84
459
3.71
10.45
4.9
3.0
—
—
estimate
—
0
0
19
36
6.07
10.00
2.3
1.1
—
—
—
0
0
19
22
10.02
9.73
2.3
1.4
—
—
—
0
0
68
340
3.28
9.49
10.1
3.7
0.00
0.00
estimate
-0.00
26
117
9
0
+∞
9.49
3.0
0.0
—
—
—
0
0
19
38
5.75
9.45
2.4
3.2
—
—
—
0
0
68
341
3.27
9.43
4.5
3.8
28.83
30.73
u/l
0.29
63
319
19
27
8.14
8.67
2.3
1.4
—
—
—
0
0
15
15
11.23
8.30
9.1
1.7
72.93
58.45
%
1.35
15
15
90
558
3.39
8.27
10.3
3.5
0.00
0.00
estimate
-0.00
43
118
76
428
3.09
8.27
2.6
2.0
94.06
98.52
pmol/l
0.28
42
216
89
549
3.35
8.23
10.0
3.5
0.00
0.00
estimate
-0.00
48
124
13
10
14.38
8.09
1.4
1.7
—
—
—
0
0
89
555
3.28
7.96
10.4
3.5
0.00
0.00
estimate
-0.00
48
128
18
27
7.63
7.95
2.1
1.7
99.72
89.70
%
0.90
18
27
48
213
3.08
7.94
4.0
2.7
—
—
—
0
0
15
17
9.89
7.81
1.5
1.6
—
—
—
0
0
7
0
+∞
7.36
4.1
0.0
403.71
—
umol/l
—
7
0
18
31
6.63
7.26
2.5
1.9
—
0.00
—
0
5
17
27
7.14
7.25
1.4
1.9
—
—
—
0
0
75
441
2.84
7.17
10.3
3.4
0.00
0.00
estimate
-0.00
42
99
14
23
6.73
5.89
2.4
2.3
225.65
204.87
%
0.21
14
23
12
17
7.70
5.59
1.6
1.2
—
—
—
0
0
11
14
8.51
5.48
1.2
1.0
—
—
—
0
0
16
35
5.10
5.41
1.5
1.5
0.28
0.21
g/l
1.92
16
35
5
0
+∞
5.24
1.2
0.0
—
—
—
0
0
8
6
14.14
5.15
3.3
2.5
—
—
—
0
0
12
22
5.93
4.74
2.4
2.7
30.08
35.18
umol/l
0.38
12
22
20
71
3.18
4.65
5.2
3.7
184.62
210.02
ng/l
0.14
20
65
12
23
5.67
4.59
2.4
1.2
—
—
—
0
0
12
23
5.67
4.59
2.4
1.2
—
—
—
0
0
0
109
0.00
4.48
0.0
2.2
—
3.81
—
0
93
42
226
2.31
4.34
1.5
1.3
7.17
0.93
u/ml
0.47
15
49
98
752
2.60
4.23
6.0
4.2
15.19
14.95
pmol/l
0.35
93
675
32
158
2.39
3.98
5.0
2.9
3.76
1.92
e6/l
0.34
16
81
6
5
12.52
3.80
10.3
9.6
625.00
817.00
nmol/l
—
6
5
16
57
3.08
3.69
4.0
1.7
—
—
—
0
0
34
179
2.25
3.63
5.2
2.6
0.49
1.03
e6/l
1.54
18
102
7
9
8.17
3.61
1.1
1.0
1132.00
1601.67
miu/ml
—
7
9
7
9
8.17
3.61
1.1
1.3
—
—
—
0
0
11
28
4.21
3.38
1.5
1.7
—
—
—
0
0
13
43
3.27
3.36
18.4
2.8
24.98
24.87
mmol/l
0.04
13
43
6
7
8.94
3.30
3.7
1.3
—
—
—
0
0
6
7
8.94
3.30
3.7
1.3
—
—
—
0
0
0
81
0.00
3.28
0.0
2.0
—
3.65
—
0
67
11
32
3.68
2.99
4.1
2.6
—
—
—
0
0
100
822
2.25
2.92
104.1
20.2
15.12
13.69
%
10.54
100
811
5
6
8.62
2.77
1.6
2.5
—
—
—
0
0
5
6
8.62
2.77
1.6
2.5
—
—
—
0
0
5
6
8.62
2.77
1.6
2.5
—
—
—
0
0
5
6
8.62
2.77
1.6
2.5
—
—
—
0
0
10
30
3.54
2.67
3.9
2.3
—
—
—
0
0
10
31
3.42
2.58
3.0
1.3
—
—
—
0
0
6
11
5.67
2.57
1.5
1.3
—
—
—
0
0
105
897
2.29
2.52
7.2
5.1
2.46
1.93
mu/l
1.54
105
805
76
590
1.77
2.36
4.7
2.7
—
—
—
0
0
19
97
2.14
2.14
6.6
3.2
35.00
29.21
u/l
0.49
14
72
9
31
3.05
2.12
1.4
1.2
—
—
—
0
0
19
331
0.49
2.12
3.4
4.7
23.26
20.86
%
—
7
163
69
837
0.59
2.07
87.0
20.4
325.71
332.36
g/l
6.34
69
831
30
188
1.79
1.90
7.8
3.7
109.24
361.14
ng/l
0.85
25
147
5
12
4.30
1.84
4.6
2.6
1.18
1.20
mmol/l
—
5
12
5
12
4.30
1.84
2.4
1.5
—
—
—
0
0
5
12
4.30
1.84
1.6
1.8
—
—
—
0
0
5
12
4.30
1.84
1.6
1.8
—
—
—
0
0
5
12
4.30
1.84
1.6
1.8
—
—
—
0
0
5
12
4.30
1.84
4.6
2.6
105.00
105.33
mmol/l
—
5
12
5
14
3.68
1.63
3.4
1.4
—
—
—
0
0
5
14
3.68
1.63
3.4
1.4
—
—
—
0
0
5
14
3.68
1.63
3.4
1.4
—
—
—
0
0
5
14
3.68
1.63
3.4
1.4
—
—
—
0
0
5
14
3.68
1.63
3.4
1.4
—
—
—
0
0
20
116
1.87
1.61
2.7
5.2
3.68
101.36
ug/l
0.84
14
99
5
15
3.43
1.54
3.4
1.3
—
—
—
0
0
15
81
1.97
1.48
3.7
2.1
34.04
5.27
ug/l
0.46
15
73
7
29
2.50
1.41
2.0
1.1
—
—
—
0
0
17
101
1.79
1.28
8.2
2.4
0.41
0.24
e6/l
0.42
17
95
5
20
2.56
1.16
1.4
1.1
—
—
—
0
0
5
21
2.44
1.10
1.2
1.3
—
—
—
0
0
5
21
2.44
1.10
1.0
1.2
—
—
—
0
0
14
86
1.71
0.96
1.4
1.4
—
—
—
0
0
25
181
1.48
0.89
1.2
1.3
35.33
23.82
iu/ml
—
6
54
6
30
2.05
0.88
1.2
1.5
—
251.75
miu/ml
—
0
12
5
28
1.82
0.67
1.0
1.8
—
7126.75
—
0
8
7
113
0.60
0.61
1.3
1.3
—
—
—
0
0
21
161
1.37
0.56
1.2
1.3
23.21
11.69
u/ml
—
8
60
6
40
1.53
0.52
1.3
1.2
—
—
—
0
0
12
85
1.46
0.49
1.5
2.6
—
—
—
0
0
13
94
1.43
0.48
1.6
2.6
—
—
—
0
0
7
50
1.42
0.46
1.1
1.2
—
122.19
—
0
17
8
114
0.68
0.39
4.4
2.6
16.07
14.43
nmol/l
—
8
106
13
157
0.81
0.24
1.6
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
1.09
—
0
11
0
10
0.00
0.21
0.0
1.2
—
196.59
—
0
10
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
11
120
0.91
0.05
19.5
6.5
—
—
—
0
0
96
970
0.95
0.04
8.4
5.1
6.89
5.95
mmol/l
3.11
89
875
42
413
1.03
0.01
2.2
2.0
1.45
1.32
mmol/l
0.53
37
340
0
7
0.00
-0.00
0.0
1.1
—
10.86
—
0
7
5
50
1.00
-0.00
4.8
3.3
14.40
1334.66
u/ml
—
5
39
0
7
0.00
-0.00
0.0
1.4
—
0.28
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
92.43
—
0
7
0
7
0.00
-0.00
0.0
1.9
—
50.03
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_FLUIDOVER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_FLUIDOVER | 3.281 [1.98, 5.44] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.135 |
During the follow-up period (1.1.1998 — 31.12.2019), 103 out of 212 females with E4_FLUIDOVER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_FLUIDOVER | 6.861 [3.77, 12.48] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.098 |
During the follow-up period (1.1.1998 — 31.12.2019), 127 out of 212 males with E4_FLUIDOVER died.
Mortality risk
Mortality risk for people of age
years, who have E4_FLUIDOVER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.229% | 1.763% |
| 5 | 1.508% | 9.368% |
| 10 | 4.476% | 22.161% |
| 15 | 8.006% | 39.888% |
| 20 | 13.834% | 56.64% |
Relationships between endpoints
↥Index endpoint: E4_FLUIDOVER – Fluid overload
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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