Other nonscarring hair loss

L12_HAIRLOSSNONSCAR

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L65
  • Cause of death: ICD-10 L65

2 out of 7 registries used, show all original rules.

480

4. Check minimum number of events

None

480

5. Include endpoints

480

6. Filter based on genotype QC (FinnGen only)

425

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Alia alopecia non cicatrisans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2372 2134 224
Only index persons 2265 2061 204
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.01
Only index persons 0.07 0.08 0.01
Median age at first event (years)
Whole population 38.44 40.23 21.33
Only index persons 39.24 40.85 22.94

-FinnGen-

Key figures

All Female Male
Number of individuals 425 411 14
Unadjusted period prevalence (%) 0.14 0.15 0.01
Median age at first event (years) 47.56 47.91 37.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
447
Matched controls
4470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L65.9
ICD-10 Finland
Nonscarring hair loss, unspecified
553.3
262.4
237
9
L65.8
ICD-10 Finland
Other specified nonscarring hair loss
518.9
123.1
117
*
C03DA01
ATC
spironolactone; oral
11.1
120.2
157
207
L65.0
ICD-10 Finland
Telogen effluvium
1043.9
90.0
85
*
L65
ICD-10 Finland
Other nonscarring hair loss
212.8
55.3
56
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.6
46.3
84
152
L64.9
ICD-10 Finland
Androgenic alopecia, unspecified
177.7
32.1
33
*
D07AC13
ATC
mometasone; topical
3.1
29.3
194
889
D07AC01
ATC
betamethasone; topical
3.0
28.6
227
1146
L63.9
ICD-10 Finland
Alopecia areata, unspecified
83.2
28.1
31
*
L70.0
ICD-10 Finland
Acne vulgaris
8.4
24.6
33
42
S23
ICPC
Hair loss/baldness
19.7
22.1
33
18
J01AA04
ATC
lymecycline; systemic
3.1
20.8
104
396
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
20.7
162
784
D07AD01
ATC
clobetasol; topical
3.0
20.5
112
448
E0000UV, ,
ATC
2.4
18.8
248
1513
L63.8
ICD-10 Finland
Other alopecia areata
198.0
18.7
19
*
D06BX01
ATC
metronidazole; topical
3.1
17.3
82
301
D07XC01
ATC
betamethasone; topical
3.2
16.6
73
256
L71
ICD-10 Finland
Rosacea
6.5
16.1
27
44
H03AA01
ATC
levothyroxine sodium; systemic
2.4
16.0
157
827
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.5
15.8
137
683
L65.2
ICD-10 Finland
Alopecia mucinosa
+∞
13.6
13
*
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
13.4
171
991
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.8
13.3
31
69
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
12.1
85
380
D10BA01
ATC
isotretinoin; oral
3.1
11.8
53
187
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
11.3
117
619
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.9
11.1
54
199
L04AX01
ATC
azathioprine; systemic
4.2
10.8
29
72
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.2
10.7
113
600
L68.0
ICD-10 Finland
Hirsutism
61.5
10.7
12
*
H02AB06
ATC
prednisolone; systemic
1.9
10.6
222
1508
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
10.5
211
1412
L21.0
ICD-10 Finland
Seborrhoea capitis
11.7
10.1
18
16
L71.9
ICD-10 Finland
Rosacea, unspecified
5.3
9.9
20
39
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
9.9
214
1459
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.8
9.7
30
83
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
9.6
137
810
G04CB01
ATC
finasteride; oral
11.0
9.4
17
16
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.9
9.2
183
1207
XQ845
NOMESCO Finland
Dermatoscopy
7.7
9.0
20
27
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.2
8.9
90
467
R53
ICD-10 Finland
Malaise and fatigue
1.9
8.8
142
872
XQ800
NOMESCO Finland
Prick test
2.6
8.5
51
210
L63.0
ICD-10 Finland
Alopecia (capitis) totalis
+∞
8.4
8
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.4
8.3
61
276
D02AX
ATC
Other emollients and protectives
4.2
8.2
22
55
L73.8
ICD-10 Finland
Other specified follicular disorders
17.6
8.1
12
7
L63
ICD-10 Finland
Alopecia areata
22.5
8.0
11
5
N05BA04
ATC
oxazepam; oral
1.8
7.8
141
893
G47.8
ICD-10 Finland
Other sleep disorders
4.0
7.8
22
57
E0001A1, ,
ATC
4.6
7.7
18
40
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.1
7.7
21
53
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
7.6
104
601
D10AX03
ATC
azelaic acid; topical
2.3
7.5
59
275
UJF32
NOMESCO Finland
Coloscopy
1.9
7.5
108
635
A02BC05
ATC
esomeprazole; systemic
1.8
7.5
186
1292
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
7.5
164
1100
T78.4
ICD-10 Finland
Allergy, unspecified
2.9
7.4
35
127
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.9
7.3
34
122
WYA10
NOMESCO Finland
Emergency care or similar visit
2.5
7.1
48
209
J01MA02
ATC
ciprofloxacin; systemic
1.8
7.0
153
1021
L82
ICD-10 Finland
Seborrhoeic keratosis
2.0
7.0
92
524
M79.6
ICD-10 Finland
Pain in limb
1.7
6.9
221
1636
L50.3
ICD-10 Finland
Dermatographic urticaria
4.2
6.9
18
44
J02AC01
ATC
fluconazole; systemic
1.7
6.9
230
1723
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.5
6.9
43
181
P01AB01
ATC
metronidazole; oral, rectal
1.7
6.8
212
1555
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.3
6.8
55
260
R01AD58
ATC
fluticasone, combinations; nasal
1.8
6.8
147
977
E03
ICD-10 Finland
Other hypothyroidism
2.5
6.7
44
189
R00.2
ICD-10 Finland
Palpitations
2.2
6.7
56
268
SBA00
NOMESCO Finland
Microbiological examinations
4.1
6.7
18
45
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
6.7
79
433
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.6
6.6
22
64
SPAT1263
SPAT
Sampling
1.7
6.5
198
1438
N06AA09
ATC
amitriptyline; systemic
2.3
6.5
49
224
A02BA02
ATC
ranitidine; systemic
2.0
6.5
80
444
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.1
6.4
16
27
L71.8
ICD-10 Finland
Other rosacea
9.4
6.3
12
13
G03HB01
ATC
cyproterone and estrogen; oral
2.0
6.3
76
419
G44.2
ICD-10 Finland
Tension-type headache
1.9
6.3
89
518
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
6.3
64
332
J34.2
ICD-10 Finland
Deviated nasal septum
3.0
6.3
27
93
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.4
6.3
43
189
L64.8
ICD-10 Finland
Other androgenic alopecia
+∞
6.3
6
*
A27
ICPC
Fear of other disease NOS
2.9
6.2
30
110
XQ848
NOMESCO Finland
Dermatological photography
3.9
6.1
18
48
A02BC02
ATC
pantoprazole; systemic
1.7
6.1
297
2418
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.5
6.1
37
153
L01
ICPC
Neck symptom/complaint
1.8
6.1
97
586
A04
ICPC
Weakness/tiredness general
1.9
6.1
86
500
J01AA07
ATC
tetracycline; systemic
1.9
6.0
85
494

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
338
2326
2.86
20.64
4.2
3.2
89.90
72.37
ug/l
1.67
327
2194
58
159
4.04
19.14
1.3
1.2
—
—
—
0
0
296
1947
2.54
19.13
2.9
2.5
77.98
77.21
nmol/l
0.17
285
1790
133
641
2.53
16.59
1.6
1.4
771.11
580.72
titre
0.37
36
139
306
2125
2.39
16.29
7.8
5.8
1.90
2.01
e9/l
0.89
284
1875
256
1658
2.27
15.95
2.4
2.0
100.10
99.04
pmol/l
0.12
147
844
298
2064
2.33
15.69
7.9
5.8
0.51
0.53
e9/l
0.74
271
1764
307
2160
2.35
15.47
7.9
6.2
0.18
0.17
e9/l
0.25
284
1882
298
2072
2.31
15.42
7.9
5.9
0.04
0.04
e9/l
0.53
271
1770
418
3445
4.29
14.96
7.0
4.8
14.45
14.52
pmol/l
0.23
399
3211
241
1554
2.20
14.79
6.1
4.4
36.80
36.73
g/l
0.07
226
1472
200
1230
2.13
13.50
1.5
1.3
1.59
1.97
u/ml
0.19
58
330
128
660
2.32
13.38
2.6
2.3
69.96
99.62
ug/g
1.37
102
505
118
590
2.36
13.22
3.1
2.3
13.87
13.90
umol/l
0.02
112
553
54
188
3.13
12.30
2.9
2.0
9.18
6.22
iu/ml
0.47
14
40
272
1923
2.06
12.16
7.8
5.7
56.38
56.49
%
0.07
263
1828
274
1954
2.04
11.81
8.0
5.9
29.62
29.54
%
0.05
264
1845
173
1058
2.04
11.40
2.6
2.1
2.52
2.74
mg/l
0.55
155
901
200
1294
1.99
11.19
7.9
5.7
—
—
—
0
0
265
1892
1.98
11.10
8.2
6.0
0.72
0.70
%
0.33
255
1751
257
1820
1.97
10.97
8.8
6.4
1.23
1.22
mmol/l
0.92
237
1551
171
1053
2.01
10.97
1.7
1.5
2.15
2.12
g/l
0.10
115
656
307
2315
2.04
10.91
10.2
8.7
3.81
3.95
e9/l
0.59
279
2003
264
1895
1.96
10.74
8.1
5.9
2.83
2.70
%
0.49
254
1759
264
1896
1.96
10.71
8.2
6.0
8.34
8.37
%
0.05
254
1765
106
551
2.21
10.60
1.2
1.2
—
—
—
0
0
169
1064
1.95
9.97
2.5
2.0
109.16
197.96
u/l
0.83
158
1012
202
1365
1.88
9.49
3.5
3.0
2.36
2.36
mmol/l
0.10
187
1247
435
3892
5.38
9.47
8.5
5.9
1.66
1.79
mu/l
2.01
423
3683
95
499
2.15
9.15
3.4
2.4
23.60
22.92
%
0.20
90
469
83
418
2.21
8.87
1.1
1.3
32.66
167.95
u/ml
9.34
28
182
24
63
3.97
8.35
1.5
1.3
—
—
—
0
0
39
141
2.93
8.30
1.4
1.3
1.33
3.22
u/ml
—
6
13
39
141
2.93
8.30
1.5
1.3
5.35
5.90
u/ml
0.04
13
25
45
176
2.73
8.29
1.2
1.3
—
1.29
—
0
8
224
1615
1.78
8.11
7.8
5.8
1.23
1.22
mmol/l
0.82
212
1484
233
1703
1.77
8.02
2.6
2.0
—
—
—
0
0
279
2165
1.77
7.64
5.0
4.5
6.37
6.35
mmol/l
0.05
264
1982
95
532
2.00
7.61
1.7
1.7
1181.82
1211.11
nmol/l
0.12
77
395
64
309
2.25
7.53
4.1
3.7
4.30
4.65
pmol/l
3.24
59
276
122
748
1.87
7.45
1.8
1.6
60748101.86
31348402.81
pmol/l
0.19
107
638
260
1989
1.73
7.37
7.5
5.7
9.86
9.52
umol/l
0.36
250
1891
67
333
2.19
7.34
5.0
3.9
7.37
7.35
ph
0.39
57
231
84
458
2.03
7.23
1.4
1.3
—
—
—
0
0
76
405
2.06
6.95
1.2
1.2
—
—
—
0
0
118
731
1.83
6.92
2.5
2.4
2.42
2.44
mmol/l
0.96
108
659
164
1121
1.73
6.87
5.6
3.7
7.39
7.40
ph
0.99
117
770
42
175
2.55
6.84
2.5
2.2
—
—
—
0
0
160
1089
1.73
6.79
1.8
1.6
22.11
21.53
nmol/l
0.17
136
938
238
1804
1.68
6.75
4.2
3.2
6.36
6.23
ph
1.02
131
989
77
417
2.02
6.73
2.4
2.0
412.85
386.41
nmol/l
0.57
68
395
21
59
3.69
6.67
1.5
1.3
—
—
—
0
0
329
2728
1.78
6.64
6.4
4.5
143.33
1438.08
e6/l
—
6
36
31
112
2.90
6.62
1.2
1.2
88.33
100.00
titre
—
6
13
142
940
1.75
6.62
1.5
1.4
17.95
29.37
iu/ml
1.81
37
279
85
485
1.93
6.39
2.1
2.0
—
—
—
0
0
169
1185
1.69
6.34
3.1
2.4
55.67
61.88
u/l
0.77
163
1089
74
405
1.99
6.27
8.4
5.4
1.03
1.05
mmol/l
0.20
65
371
45
202
2.37
6.26
2.2
2.0
10.54
4.39
ug/l
0.51
40
177
280
2245
1.66
6.15
4.6
3.6
0.00
9.68
estimate
1.08
63
469
346
2941
1.78
6.06
10.8
7.3
74.73
75.28
u/l
0.09
334
2774
431
3973
3.37
6.00
19.9
12.6
16.45
20.09
mg/l
2.07
355
3173
121
792
1.72
5.76
2.8
2.5
7.03
8.78
e6/l
0.41
112
711
275
2224
1.61
5.57
4.6
3.6
0.00
0.00
estimate
0.50
61
458
278
2260
1.61
5.46
4.7
3.7
0.00
0.01
estimate
0.50
60
445
82
486
1.84
5.45
1.6
1.4
—
—
—
0
0
33
137
2.52
5.43
4.1
1.7
0.22
0.24
g/l
0.68
33
131
19
58
3.38
5.36
1.5
1.4
0.38
0.49
g/l
0.39
12
49
194
1462
1.58
5.19
7.2
9.2
1.09
1.12
inr
0.64
173
1192
75
441
1.84
5.10
1.7
1.5
—
—
—
0
0
101
649
1.72
5.08
5.7
3.4
339.22
179.53
ng/l
0.21
65
409
123
835
1.65
5.04
4.0
3.7
—
—
—
0
0
146
1036
1.61
5.00
5.0
4.4
—
—
—
0
0
66
375
1.89
4.99
1.6
1.3
18.33
23.57
iu/l
0.77
57
328
169
1246
1.57
4.90
3.3
3.1
30.58
30.97
ng/l
0.01
95
714
72
425
1.83
4.83
3.2
2.5
6.30
5.51
umol/l
0.17
61
372
15
35
4.40
4.67
1.1
1.4
0.40
0.33
g/l
—
8
26
15
35
4.40
4.67
1.1
1.4
2.93
3.12
g/l
—
7
25
15
35
4.40
4.67
1.1
1.4
6.00
6.04
g/l
—
8
26
125
871
1.60
4.56
1.4
1.3
11.19
9.29
u/ml
0.11
60
334
58
329
1.88
4.41
2.9
4.6
0.72
0.99
%
0.42
18
92
160
1188
1.54
4.40
4.0
3.0
85.79
41.24
e6/l
0.40
123
873
191
1474
1.52
4.39
5.0
3.7
133.89
58.24
e6/l
0.66
131
946
14
34
4.22
4.24
1.1
1.4
—
—
—
0
0
55
311
1.88
4.22
2.7
4.6
0.31
0.73
%
1.18
16
81
393
3577
1.82
4.15
6.6
5.4
37.80
37.69
mmol/mol
0.09
379
3378
77
485
1.71
4.13
3.0
3.6
4.40
5.00
e9/l
0.38
68
436
55
314
1.86
4.10
2.9
4.8
0.07
0.11
%
0.21
15
75
21
81
2.67
4.03
1.3
1.3
357.93
213.42
u/ml
1.22
14
50
7
7
10.13
4.02
6.4
2.4
—
—
—
0
0
28
125
2.32
3.99
1.7
1.4
274.59
319.84
ug/g
0.73
22
67
36
179
2.10
3.96
4.9
3.5
7.41
7.42
ph
0.81
27
148
14
37
3.87
3.92
1.4
1.5
20.94
20.70
ng/l
0.03
14
37
34
168
2.11
3.81
1.4
1.2
—
—
—
0
0
30
141
2.21
3.80
1.1
1.3
7.54
10.66
u/l
1.08
19
120
54
315
1.81
3.76
2.4
2.4
10.16
17.57
au/ml
—
7
30
49
278
1.86
3.73
5.0
3.7
82.85
74.45
ng/l
0.28
41
247
208
1679
1.45
3.61
4.3
3.4
0.00
0.03
estimate
1.64
51
370
225
1845
1.44
3.58
11.6
9.6
0.00
0.00
e9/l
1.07
185
1489
11
26
4.31
3.53
1.5
1.7
—
—
—
0
0
24
106
2.34
3.52
1.4
1.4
23.16
21.18
u/l
0.09
18
90
19
75
2.60
3.51
2.9
2.2
7.46
6.72
pmol/l
0.16
19
75
6
6
10.11
3.50
1.0
1.2
—
—
—
0
0
20
82
2.51
3.43
1.3
1.5
—
—
—
0
0
25
114
2.26
3.42
2.0
2.2
1.52
1.38
g/l
0.38
25
99
28
135
2.15
3.36
1.5
1.4
0.48
0.41
nmol/l
0.20
21
112
98
691
1.54
3.31
2.7
2.6
484.28
501.25
mosm/kgh2o
0.30
90
597
25
116
2.22
3.29
1.1
1.3
—
—
—
0
0
169
1331
1.43
3.27
4.2
2.7
—
—
—
0
0
6
7
8.67
3.27
1.0
1.0
—
—
—
0
0
61
386
1.67
3.22
2.6
2.3
30.78
33.38
u/l
0.29
50
319
53
324
1.72
3.17
3.1
5.1
0.00
0.18
%
1.24
12
71
26
126
2.13
3.09
4.0
3.5
168.47
358.64
mg/l
0.84
15
47
114
842
1.48
3.07
1.9
1.8
—
—
—
0
0
61
393
1.64
3.01
2.2
2.1
0.00
0.06
estimate
—
10
90
18
75
2.46
3.01
1.3
1.4
164.57
158.93
au/ml
—
7
22
53
331
1.68
2.94
2.5
2.6
1.74
1.78
%
0.14
48
300
126
956
1.44
2.94
2.8
1.7
0.90
0.95
mg/l
0.10
88
728
8
17
4.77
2.93
1.1
1.1
122.75
128.18
nmol/l
—
8
17
16
64
2.56
2.90
1.1
1.2
—
—
—
0
0
133
1022
1.43
2.89
4.2
2.9
0.14
0.36
e6/l
2.66
93
708
7
13
5.45
2.88
1.1
2.3
—
—
—
0
0
316
2813
1.42
2.86
4.4
3.1
40.46
35.73
u/l
0.48
301
2670
76
525
1.54
2.80
1.3
1.2
—
—
—
0
0
5
6
8.41
2.75
1.0
1.3
—
—
—
0
0
84
598
1.50
2.69
1.8
1.6
—
—
—
0
0
150
1190
1.39
2.69
7.2
5.7
—
—
—
0
0
232
1977
1.36
2.65
2.9
2.7
—
—
estimate
—
0
0
432
4144
2.27
2.61
15.6
10.6
23.76
23.59
u/l
0.11
427
4041
40
242
1.72
2.51
2.4
2.3
66.27
72.77
e9/l
0.56
29
176
42
258
1.69
2.50
4.7
3.2
—
—
—
0
0
161
1306
1.36
2.49
2.5
2.1
—
—
—
0
0
431
4138
2.16
2.47
16.9
11.3
—
—
—
0
0
11
38
2.94
2.43
1.5
3.5
—
—
—
0
0
9
27
3.38
2.40
1.1
1.3
—
—
—
0
0
8
22
3.68
2.37
1.6
3.0
495.87
674.45
u/ml
—
8
22
9
28
3.26
2.32
1.3
3.0
—
—
—
0
0
35
209
1.73
2.31
2.2
2.1
0.00
0.01
estimate
—
9
69
157
1281
1.35
2.31
3.6
3.0
0.02
0.02
estimate
0.05
54
377
151
1225
1.35
2.30
3.8
3.2
6.92
7.46
mmol/l
0.71
124
1041
9
29
3.15
2.23
1.3
1.1
—
—
—
0
0
23
122
1.93
2.20
6.1
3.8
—
—
—
0
0
32
190
1.74
2.16
1.7
1.7
18.87
7.73
u/ml
—
6
43
39
246
1.64
2.12
1.5
1.7
—
—
—
0
0
12
49
2.49
2.12
1.7
3.6
1.33
1.27
%
0.02
12
44
48
320
1.56
2.09
1.3
1.3
—
—
—
0
0
7
20
3.54
2.06
1.9
1.2
—
—
—
0
0
7
20
3.54
2.06
6.7
1.6
989.00
781.15
mg
—
7
20
37
233
1.64
2.03
1.5
1.8
—
—
—
0
0
39
249
1.62
2.03
1.5
1.7
—
—
—
0
0
13
57
2.32
1.99
1.2
2.0
—
—
—
0
0
52
358
1.51
1.97
3.0
2.2
501.55
6160.01
u/l
2.95
19
162
7
21
3.37
1.97
1.3
1.4
—
—
—
0
0
147
1213
1.32
1.95
5.2
3.7
0.00
0.00
estimate
0.80
60
451
29
174
1.71
1.91
5.4
3.5
23.83
24.41
mmol/l
0.42
29
174
16
79
2.06
1.87
3.5
3.5
3.98
4.33
e9/l
0.28
16
79
48
329
1.51
1.86
2.8
4.1
4.43
10.17
ug/l
1.46
31
263
38
247
1.59
1.86
1.4
1.8
—
—
—
0
0
38
247
1.59
1.86
1.5
1.7
—
—
—
0
0
6
17
3.56
1.84
1.0
1.0
—
22.79
—
0
5
6
17
3.56
1.84
1.7
1.1
—
—
—
0
0
5
12
4.20
1.83
2.0
3.9
0.64
0.63
mmol/l
—
5
12
118
952
1.33
1.82
4.9
3.5
98.20
96.69
%
0.32
113
926
122
994
1.31
1.75
4.1
3.4
1.02
1.02
kg/l
0.15
82
641
146
1220
1.29
1.74
2.4
2.1
—
—
—
0
0
7
24
2.95
1.73
1.3
1.1
—
—
—
0
0
75
569
1.38
1.72
4.1
2.7
3.50
4.05
e6/l
0.19
36
244
44
303
1.50
1.69
4.3
3.3
7.37
7.39
ph
0.75
23
168
10
41
2.47
1.65
1.5
1.2
—
—
—
0
0
54
390
1.44
1.64
1.5
1.4
—
—
—
0
0
128
1059
1.29
1.64
4.2
3.4
87.05
39.81
mg/l
0.33
77
642
54
394
1.42
1.56
1.5
1.4
—
—
—
0
0
13
64
2.06
1.55
1.2
1.2
—
—
—
0
0
7
27
2.62
1.52
1.9
2.1
49.47
44.97
%
—
7
27
7
27
2.62
1.52
1.6
1.4
62.86
69.70
umol/l
—
7
27
19
109
1.78
1.49
6.6
7.6
—
—
—
0
0
9
37
2.46
1.48
1.6
1.2
—
—
—
0
0
193
1697
1.24
1.46
2.0
1.9
1.24
1.30
mmol/l
0.55
164
1462
403
3867
1.43
1.45
5.5
4.6
4.78
4.79
mmol/l
0.12
387
3654
14
74
1.92
1.40
2.1
2.4
—
—
—
0
0
31
207
1.53
1.39
1.5
2.4
—
—
—
0
0
41
293
1.44
1.34
5.0
3.2
1.23
1.23
mmol/l
0.41
34
250
12
61
1.99
1.34
1.3
1.3
—
—
—
0
0
127
1075
1.25
1.33
5.0
4.0
20.32
8.39
mg/mmol
0.35
76
629
404
3893
1.39
1.26
6.1
5.2
2.78
2.81
mmol/l
0.31
387
3665
15
86
1.77
1.20
1.7
2.7
1.60
1.44
index
—
5
43
121
1030
1.24
1.20
2.0
1.8
—
—
—
0
0
379
3627
1.30
1.17
4.6
3.8
1.24
1.21
mmol/l
0.43
360
3381
11
58
1.92
1.13
2.7
2.1
—
—
—
0
0
36
261
1.41
1.12
1.5
1.2
—
—
—
0
0
43
322
1.37
1.11
1.5
1.4
—
—
—
0
0
26
179
1.48
1.05
1.7
2.2
—
—
—
0
0
5
22
2.29
1.03
1.0
1.5
55.00
81.95
ng/l
—
5
22
44
335
1.35
1.03
2.0
1.7
—
—
—
0
0
106
904
1.23
1.03
2.8
2.6
304.56
309.80
umol/l
0.22
97
813
7
34
2.08
1.03
1.3
1.1
132.57
111.53
pmol/l
—
7
34
21
139
1.54
1.02
5.2
8.2
—
—
—
0
0
17
107
1.61
1.01
4.1
2.7
1.42
1.41
mg/l
0.02
17
93
17
107
1.61
1.01
3.4
3.2
58.95
59.42
%
0.06
17
107
5
23
2.19
0.98
1.0
1.5
5.38
5.38
mmol/l
—
5
23
5
23
2.19
0.98
1.2
1.1
868.20
1623.65
miu/ml
—
5
23
398
3852
1.30
0.97
5.4
4.5
1.58
1.56
mmol/l
0.44
381
3619
40
304
1.35
0.96
4.4
3.2
5.80
5.77
kpa
0.05
40
298
6
27
2.24
0.94
1.2
1.1
—
—
—
0
0
79
664
1.23
0.89
1.6
1.5
—
—
—
0
0
33
247
1.36
0.88
2.4
1.7
—
—
—
0
0
8
43
1.88
0.87
1.8
2.7
—
—
—
0
0
44
345
1.31
0.87
1.9
2.3
5.88
6.20
ph
1.60
28
226
6
30
2.01
0.87
1.0
1.1
—
—
—
0
0
388
3754
1.25
0.87
5.3
4.5
5.76
5.70
mmol/l
0.40
367
3497
11
64
1.74
0.87
2.4
2.4
—
—
—
0
0
6
33
1.83
0.79
3.5
1.8
—
—
—
0
0
14
90
1.57
0.79
1.1
1.0
2.94
3.87
u/ml
—
8
42
32
246
1.32
0.74
10.9
8.0
—
—
—
0
0
7
39
1.81
0.72
1.1
1.2
—
—
—
0
0
5
27
1.86
0.68
1.6
2.8
1.96
2.90
nmol/l
—
5
27
28
214
1.33
0.68
1.2
1.1
—
—
—
0
0
44
362
1.24
0.63
5.4
3.6
—
—
—
0
0
8
49
1.64
0.62
1.3
1.2
—
—
—
0
0
10
63
1.60
0.62
2.2
2.0
13.09
13.27
%
—
10
63
26
200
1.32
0.62
1.6
1.8
—
—
—
0
0
22
165
1.35
0.61
2.0
2.1
2.14
4.07
iu/l
—
9
72
16
114
1.42
0.59
1.4
1.2
—
—
—
0
0
6
38
1.59
0.54
1.5
3.2
—
—
—
0
0
11
74
1.50
0.54
3.6
3.8
—
—
—
0
0
12
168
0.71
0.51
1.0
1.1
—
0.58
—
0
22
10
67
1.50
0.50
5.2
1.9
58.50
56.80
%
—
10
67
7
45
1.56
0.49
1.7
1.6
—
—
—
0
0
7
45
1.56
0.49
1.7
1.6
—
—
—
0
0
7
45
1.56
0.49
1.7
1.6
—
—
—
0
0
7
45
1.56
0.49
1.7
1.6
—
—
—
0
0
7
47
1.50
0.47
1.1
1.6
3.96
88.29
u/ml
—
7
47
13
176
0.73
0.47
1.0
1.1
1.54
1.61
g/l
0.76
13
176
13
94
1.39
0.46
1.0
1.1
2.02
1.12
u/ml
—
5
44
21
165
1.29
0.46
1.6
1.4
0.31
0.26
mg/l
—
6
66
7
51
1.38
0.44
1.3
1.1
—
—
—
0
0
14
184
0.75
0.42
1.0
1.2
0.89
0.87
g/l
0.07
14
184
5
32
1.57
0.42
11.0
5.8
15.90
12.66
mg/l
—
5
27
5
32
1.57
0.42
1.0
1.0
—
—
—
0
0
16
123
1.31
0.41
1.1
1.1
4.82
3.47
u/ml
—
7
66
26
214
1.23
0.40
1.1
1.1
—
—
—
0
0
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
5
35
1.43
0.39
1.8
13.3
6.90
6.27
mmol/l
—
5
29
21
169
1.25
0.39
1.4
1.4
58.11
192.37
pmol/l
1.15
21
164
355
3471
1.11
0.37
23.6
16.2
332.15
331.51
g/l
0.72
355
3450
46
404
1.15
0.37
8.8
6.1
104.83
104.19
mmol/l
0.46
46
404
178
1696
1.08
0.33
3.4
2.8
—
—
—
0
0
20
241
0.82
0.32
1.6
1.6
—
—
—
0
0
36
314
1.16
0.32
9.4
8.8
7.42
7.41
ph
0.15
21
175
7
57
1.23
0.29
3.0
2.2
—
—
—
0
0
19
158
1.21
0.28
3.8
1.8
20.38
20.24
s
0.06
13
140
21
177
1.20
0.28
10.9
9.4
93.37
94.66
%
0.39
21
177
12
95
1.27
0.26
1.0
1.1
0.53
1.08
u/ml
—
5
40
20
235
0.84
0.26
1.6
1.5
—
—
—
0
0
10
77
1.31
0.26
1.4
1.2
—
—
—
0
0
15
123
1.23
0.25
1.0
1.2
—
—
—
0
0
9
73
1.24
0.25
1.1
1.0
—
—
—
0
0
6
82
0.73
0.24
1.0
1.0
—
—
—
0
0
11
88
1.26
0.22
1.5
1.1
—
—
—
0
0
145
1392
1.06
0.22
1.7
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
8.89
—
0
10
0
10
0.00
0.21
0.0
1.1
—
40.20
—
0
5
0
13
0.00
0.21
0.0
2.1
—
28.00
—
0
7
14
165
0.84
0.19
1.1
1.3
—
—
—
0
0
21
185
1.14
0.18
2.0
1.2
—
—
—
0
0
26
236
1.11
0.15
1.5
1.3
294.73
285.88
miu/ml
0.03
11
117
20
179
1.12
0.14
11.3
9.3
1.03
1.20
%
0.61
20
179
18
160
1.13
0.14
3.6
2.3
0.64
0.61
%
0.09
18
160
18
161
1.12
0.13
3.8
2.3
0.81
1.15
%
1.95
18
161
12
106
1.14
0.10
1.0
1.1
—
—
—
0
0
12
106
1.14
0.10
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
1.4
1.5
303.40
277.81
mosm/kgh2o
—
5
36
6
56
1.07
0.08
1.2
1.1
—
—
—
0
0
6
57
1.05
0.08
2.5
2.0
17.32
16.20
%
—
6
57
12
133
0.90
0.07
7.1
7.1
1.92
1.52
%
1.05
12
127
6
70
0.86
0.07
4.0
4.5
3.47
3.78
mmol/l
—
6
70
8
74
1.08
0.07
1.0
1.0
—
—
—
0
0
13
118
1.10
0.07
1.5
1.2
397.69
404.98
mg/l
0.03
13
111
13
118
1.10
0.07
7.1
7.8
1.13
0.88
%
1.55
13
112
15
139
1.08
0.05
1.9
1.8
—
—
—
0
0
14
133
1.05
0.01
1.1
1.1
—
—
—
0
0
43
438
0.98
0.01
1.9
1.7
3.26
3.38
mmol/l
0.26
29
314
18
173
1.04
0.01
12.2
9.5
0.69
0.61
%
0.35
18
173
11
106
1.04
0.00
1.3
1.2
3.64
9.54
e6/l
0.43
11
80
12
116
1.04
0.00
1.8
1.8
—
—
—
0
0
11
107
1.03
0.00
1.3
1.2
23.09
55.73
e6/l
0.63
11
84
13
133
0.98
0.00
1.8
2.8
24.60
25.09
mmol/l
0.12
13
128
12
122
0.98
0.00
2.6
4.3
36.89
36.95
°c
0.54
12
122
60
598
1.00
0.00
1.9
1.9
—
—
—
0
0
18
179
1.01
0.00
3.9
1.8
—
—
—
0
0
45
451
1.00
0.00
1.4
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
3.4
—
53.94
—
0
9
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.60
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
6.12
—
0
8
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
—
—
0
0
8
82
0.98
-0.00
3.3
4.1
1.20
1.32
mmol/l
—
8
82
0
6
0.00
-0.00
0.0
1.7
—
56.00
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
125.97
—
0
6
0
5
0.00
-0.00
0.0
4.6
—
0.18
—
0
5
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
98
0.92
-0.00
2.3
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_HAIRLOSSNONSCAR and mortality.

Females

Parameter HR [95% CI] p-value
L12_HAIRLOSSNONSCAR 1.293 [1.01, 1.66] 0.046
Birth year 0.992 [0.98, 1.0] 0.074

During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 1581 females with L12_HAIRLOSSNONSCAR died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HAIRLOSSNONSCAR.

N-year risk Females Males
1 0.144% No data
5 0.728% No data
10 1.747% No data
15 3.274% No data
20 5.749% No data

Relationships between endpoints

Index endpoint: L12_HAIRLOSSNONSCAR – Other nonscarring hair loss

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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