Telogen effluvium

L12_TELOGEFFLU

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L65.0#
  • Cause of death: ICD-10 L65.0#

2 out of 7 registries used, show all original rules.

85

4. Check minimum number of events

None

85

5. Include endpoints

None

85

6. Filter based on genotype QC (FinnGen only)

78

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L65
Name in latin
Effluvium telogenicum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 541 499 35
Only index persons 520 488 32
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.02 0.02 0.00
Median age at first event (years)
Whole population 37.78 39.08 18.84
Only index persons 38.14 39.45 18.28

-FinnGen-

Key figures

All Female Male
Number of individuals 78 71 7
Unadjusted period prevalence (%) 0.02 0.03 0.00
Median age at first event (years) 51.98 52.59 45.88

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
80
Matched controls
800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L65.0
ICD-10 Finland
Telogen effluvium
+∞
115.1
80
*
C03DA01
ATC
spironolactone; oral
6.9
12.4
23
44
D07AC01
ATC
betamethasone; topical
4.6
10.4
48
197
L65.9
ICD-10 Finland
Nonscarring hair loss, unspecified
112.8
9.6
10
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
12
10
13.85
7.36
1.1
1.0
17.86
21.20
umol/l
—
12
10
35
174
2.80
4.71
2.5
2.3
1.95
2.78
mg/l
2.36
30
146
80
693
+∞
4.42
23.7
15.3
21.39
17.94
mg/l
0.39
68
551
25
110
2.85
4.16
1.6
1.6
1213.04
1100.97
nmol/l
0.19
19
83
24
105
2.84
4.02
1.2
1.2
—
—
—
0
0
37
207
2.47
3.75
1.4
1.2
1.13
1.96
u/ml
0.42
12
52
19
77
2.92
3.63
1.4
1.2
—
—
—
0
0
8
13
6.70
3.60
1.0
1.2
—
—
—
0
0
25
119
2.60
3.52
1.5
1.5
1013.33
638.71
titre
—
6
31
9
18
5.49
3.48
1.0
1.2
—
—
—
0
0
6
8
7.99
3.11
1.5
1.4
—
—
—
0
0
35
206
2.24
3.03
1.5
1.6
21.52
20.42
nmol/l
0.14
28
171
53
375
2.22
2.84
9.1
6.1
0.52
0.54
e9/l
0.28
45
332
5
6
8.78
2.79
1.0
1.3
—
—
—
0
0
31
179
2.19
2.77
1.4
1.3
12.91
22.95
iu/ml
—
10
63
39
247
2.13
2.76
9.1
5.8
—
—
—
0
0
53
379
2.18
2.72
9.2
6.1
0.05
0.04
e9/l
1.08
45
333
54
389
2.19
2.72
9.1
6.0
1.84
1.89
e9/l
0.22
47
354
13
51
2.85
2.59
5.2
3.9
4.18
4.49
pmol/l
0.83
13
43
54
394
2.14
2.56
9.6
6.6
0.21
0.17
e9/l
0.94
47
356
28
160
2.15
2.54
5.7
1.8
1.39
1.13
mg/l
0.18
19
126
6
13
4.89
2.31
1.0
2.8
10.88
10.15
mg/l
—
6
13
10
35
3.12
2.30
2.6
2.1
—
—
—
0
0
34
216
2.00
2.29
8.9
3.5
7.39
7.40
ph
0.63
25
149
19
98
2.23
2.18
1.4
1.2
—
—
—
0
0
28
171
1.98
2.08
1.3
1.3
24.59
6.53
u/ml
0.34
14
63
42
299
1.85
1.94
3.4
2.0
—
—
—
0
0
54
421
1.87
1.82
10.6
10.7
3.84
4.04
e9/l
0.31
47
374
6
18
3.51
1.78
6.7
1.6
11.75
5.04
pmol/l
—
6
18
44
324
1.80
1.77
2.6
2.0
102.29
100.46
pmol/l
0.08
27
153
7
24
3.09
1.76
1.1
1.1
—
—
—
0
0
44
325
1.79
1.74
3.0
3.4
6.46
6.29
ph
0.50
26
175
28
182
1.83
1.68
1.6
1.3
2.87
2.12
g/l
1.22
19
100
10
43
2.51
1.66
6.9
3.1
—
—
—
0
0
44
330
1.74
1.62
15.6
9.7
0.00
0.00
e9/l
-0.00
36
266
51
400
1.76
1.59
3.9
3.8
0.00
0.00
estimate
-0.00
13
75
17
95
2.00
1.58
2.2
2.7
—
—
—
0
0
15
80
2.08
1.57
15.9
5.6
1.04
1.07
mmol/l
0.14
15
75
15
81
2.05
1.52
1.3
1.5
—
—
—
0
0
6
22
2.86
1.46
4.3
3.4
—
—
—
0
0
50
397
1.69
1.42
3.7
3.8
0.00
0.00
estimate
-0.00
13
72
6
23
2.73
1.39
1.3
1.3
—
—
—
0
0
32
227
1.68
1.39
2.8
2.1
152.41
137.89
u/l
0.09
27
222
5
17
3.06
1.38
1.8
1.2
—
—
—
0
0
23
150
1.75
1.34
2.2
1.8
—
—
—
0
0
44
343
1.63
1.31
3.2
3.0
—
—
estimate
—
0
0
24
160
1.71
1.29
5.3
4.5
—
—
—
0
0
39
297
1.61
1.26
2.8
3.6
0.00
0.00
estimate
—
10
60
50
405
1.63
1.25
3.9
3.9
0.00
0.00
estimate
-0.00
11
73
6
26
2.41
1.21
2.0
1.2
—
—
—
0
0
6
26
2.41
1.21
1.2
2.0
0.25
0.22
g/l
—
6
26
32
236
1.59
1.16
7.4
3.2
—
—
—
0
0
9
50
1.90
1.00
1.2
2.0
—
—
—
0
0
80
769
+∞
0.98
34.0
22.8
131.60
133.13
g/l
0.58
80
762
80
769
+∞
0.98
34.3
23.1
39.74
40.02
%
0.32
80
762
80
769
+∞
0.98
33.9
22.6
4.36
4.44
e12/l
1.16
80
756
80
769
+∞
0.98
34.0
22.6
6.73
6.52
e9/l
0.44
80
756
80
769
+∞
0.98
33.8
22.5
30.44
30.15
pg
0.83
80
762
13
78
1.80
0.98
1.2
1.1
—
—
—
0
0
17
111
1.67
0.98
2.0
1.7
—
—
—
0
0
80
768
+∞
0.97
33.8
22.6
91.54
90.80
fl
0.70
80
761
80
768
+∞
0.97
34.1
22.6
266.51
261.99
e9/l
0.22
80
759
33
254
1.51
0.96
2.8
3.4
12.98
18.61
ng/l
1.41
17
155
30
229
1.50
0.90
1.6
1.6
—
—
—
0
0
6
31
2.01
0.86
2.7
1.6
—
—
—
0
0
17
115
1.61
0.86
8.9
3.7
0.81
0.80
mmol/l
0.07
17
108
14
90
1.67
0.85
1.8
1.7
—
—
—
0
0
0
24
0.00
0.80
0.0
3.6
—
36.90
—
0
24
0
25
0.00
0.80
0.0
1.2
—
—
—
0
0
29
225
1.45
0.79
3.0
2.4
—
—
—
0
0
6
109
0.51
0.79
1.8
1.5
—
—
—
0
0
9
54
1.75
0.78
6.1
8.8
1.87
1.09
mmol/l
—
9
54
10
60
1.76
0.76
2.1
1.6
—
—
—
0
0
10
60
1.76
0.76
1.8
1.4
—
—
—
0
0
65
596
1.48
0.63
27.4
18.6
13.69
13.57
%
0.36
65
589
28
225
1.38
0.61
2.5
3.2
0.00
0.00
estimate
—
10
60
0
21
0.00
0.61
0.0
2.7
—
1.40
—
0
21
0
21
0.00
0.61
0.0
1.7
—
24.96
—
0
21
25
198
1.38
0.59
4.9
3.2
0.27
0.39
e6/l
0.34
19
134
6
36
1.72
0.58
7.7
2.8
25.98
24.86
mmol/l
—
6
36
29
237
1.35
0.57
5.0
3.2
39.67
21.16
e6/l
0.36
24
171
11
74
1.56
0.57
1.6
1.5
—
—
—
0
0
33
276
1.33
0.55
6.1
4.2
34.14
41.34
e6/l
0.11
24
182
6
39
1.58
0.54
8.0
7.6
24.13
24.56
mmol/l
—
6
39
14
101
1.47
0.54
2.1
1.6
—
—
—
0
0
7
45
1.61
0.50
2.3
1.0
—
—
—
0
0
24
194
1.34
0.50
4.3
3.0
—
—
estimate
—
0
0
22
176
1.34
0.49
5.2
5.0
—
—
—
0
0
28
234
1.30
0.46
10.3
7.3
—
—
—
0
0
5
31
1.65
0.44
1.2
1.7
—
8.30
—
0
5
0
18
0.00
0.40
0.0
2.7
—
3.92
—
0
18
5
36
1.41
0.39
1.2
1.1
—
—
—
0
0
24
203
1.26
0.35
3.4
3.0
28.49
38.54
mg/l
0.24
15
120
24
204
1.25
0.34
3.2
3.9
0.00
0.00
estimate
-0.00
12
72
7
53
1.35
0.32
10.0
9.4
—
—
—
0
0
7
56
1.27
0.30
3.0
3.5
77.91
73.30
e9/l
—
7
42
8
65
1.26
0.28
5.8
2.7
5.52
5.76
kpa
—
8
65
8
66
1.24
0.28
5.8
2.6
1.67
2.02
mmol/l
—
8
57
5
38
1.34
0.23
1.2
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
3.90
—
0
10
0
10
0.00
0.21
0.0
2.0
—
107.80
—
0
10
0
10
0.00
0.21
0.0
2.0
—
1.20
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
10.08
—
0
12
0
13
0.00
0.21
0.0
1.5
—
91.22
—
0
13
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
52
1.17
0.19
3.7
2.6
8.43
4.24
kpa
—
6
52
7
57
1.25
0.19
3.0
3.4
—
—
—
0
0
23
208
1.15
0.16
3.9
3.5
10.02
6.61
mg/mmol
0.23
14
117
20
185
1.11
0.09
2.8
2.1
—
—
—
0
0
6
56
1.08
0.09
1.3
1.3
—
—
—
0
0
7
63
1.12
0.08
2.0
2.0
2.86
3.63
mmol/l
—
7
50
6
71
0.83
0.08
6.5
15.5
0.30
1.25
mmol/l
—
6
63
8
93
0.84
0.07
8.3
7.0
103.13
104.28
mmol/l
—
8
93
28
290
0.95
0.04
3.8
3.0
—
—
—
0
0
70
702
0.98
0.00
5.6
4.7
5.60
5.74
mmol/l
0.67
65
649
0
8
0.00
0.00
0.0
1.4
—
95.74
—
0
8
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
67.88
—
0
8
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
18.6
—
1012.29
—
0
7
0
7
0.00
0.00
0.0
26.3
—
1946.86
—
0
7
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
83.40
—
0
5
0
8
0.00
0.00
0.0
1.3
—
7.14
—
0
8
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
1.70
—
0
5
0
8
0.00
0.00
0.0
1.0
—
31.88
—
0
8
8
84
0.95
-0.00
2.3
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_TELOGEFFLU and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_TELOGEFFLU.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: L12_TELOGEFFLU – Telogen effluvium

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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