No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1168 |
4. Check minimum number of eventsNone |
1168 |
5. Include endpointsNone |
1168 |
6. Filter based on genotype QC (FinnGen only) |
1052 |
Control definitions (FinnGen only)
- Control exclude
- M13_OTHERBONE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M94
- Name in latin
- Chondromalacia
Similar endpoints
↥List of similar endpoints to
Chondromalacia
based on the number of shared cases.
Similar with more cases:
- Chondropathies
- Other disorders of bone
- Osteopathies and chondropathies
- Diseases of the musculoskeletal system and connective tissue
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6397 | 3429 | 2943 |
| Only index persons | 6277 | 3389 | 2888 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.08 |
| Only index persons | 0.12 | 0.12 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 43.93 | 44.37 | 43.45 |
| Only index persons | 43.84 | 44.31 | 43.28 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1052 | 652 | 400 |
| Unadjusted period prevalence (%) | 0.21 | 0.23 | 0.18 |
| Median age at first event (years) | 46.30 | 45.16 | 48.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1082
- Matched controls
- 10820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
21.7
307.7
466
364
M94.2
ICD-10 Finland
Chondromalacia
+∞
307.7
1082
5
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
23.0
307.7
288
168
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
9.0
266.7
441
766
M22.4
ICD-10 Finland
Chondromalacia patellae
16.9
236.0
211
153
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
8.2
226.0
390
698
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
7.8
199.9
345
611
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
10.9
197.1
238
274
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
35.5
161.8
103
32
M23.8
ICD-10 Finland
Other internal derangements of knee
9.2
124.2
163
205
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
14.1
124.0
118
93
M17.1
ICD-10 Finland
Other primary gonarthrosis
4.2
108.8
433
1497
NG2AA
NOMESCO Finland
Patella X-ray examination
9.3
89.1
112
132
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
4.3
85.5
272
784
M01AX05
ATC
glucosamine; oral
3.6
74.8
319
1118
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.5
61.6
269
945
M25.5
ICD-10 Finland
Pain in joint
2.7
53.6
532
2890
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.3
50.7
145
378
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
12.8
49.0
48
39
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
3.5
47.1
189
622
S83.2
ICD-10 Finland
Tear of meniscus, current
4.0
46.7
149
420
WX320
NOMESCO Finland
Spinalanesthesy
2.6
45.2
362
1742
L15
ICPC
Knee symptom/complaint
2.6
44.9
392
1965
M01AH05
ATC
etoricoxib; oral
2.8
43.6
842
6034
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
4.5
43.5
114
277
NGT99
NOMESCO Finland
Other operation on knee or lower leg
111.9
40.0
43
*
M23.3
ICD-10 Finland
Other meniscus derangements
7.8
38.9
55
74
M09AX01
ATC
hyaluronic acid; parenteral
5.0
37.2
84
180
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
3.0
36.7
194
745
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.8
36.0
213
869
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.1
34.0
100
264
M01AB05
ATC
diclofenac; systemic, rectal
2.4
31.8
822
6201
M01AE02
ATC
naproxen; oral, rectal
2.2
31.7
711
5061
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
29.2
562
3731
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
7.2
27.3
41
59
N02AX02
ATC
tramadol; systemic, rectal
2.0
26.7
524
3466
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
3.3
26.3
106
345
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
24.4
112
394
M24.2
ICD-10 Finland
Disorder of ligament
6.3
23.4
40
66
M01AC06
ATC
meloxicam; systemic, rectal
1.9
22.5
451
2957
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.9
22.3
115
431
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.0
21.7
339
2040
1220
FHL
Arthroscopy
3.6
20.6
69
199
N03AX16
ATC
[U] pregabalin
2.0
20.2
285
1649
H25.8
ICD-10 Finland
Other senile cataract
2.7
19.7
113
448
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
19.4
494
3444
M01AH01
ATC
celecoxib; oral
2.1
19.3
223
1199
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
6.9
18.8
29
43
A02BC05
ATC
esomeprazole; systemic
1.8
18.6
476
3311
B01AF01
ATC
rivaroxaban; oral
2.3
18.4
158
754
M79.6
ICD-10 Finland
Pain in limb
1.8
18.3
526
3777
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
18.1
519
3721
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.3
17.5
149
708
Z00.0
ICD-10 Finland
General medical examination
2.0
17.5
234
1323
M54.5
ICD-10 Finland
Low back pain
1.8
17.3
447
3098
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
4.1
17.3
48
121
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
17.3
223
1244
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
4.1
17.1
47
118
L90
ICPC
Osteoarthrosis of knee
2.6
17.0
101
407
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
4.0
16.5
47
121
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
15.7
327
2119
N02BE01
ATC
paracetamol; systemic, rectal
2.5
15.6
992
8844
M01AB16
ATC
aceclofenac; oral
3.8
15.4
48
132
X58
ICD-10 Finland
Exposure to other specified factors
2.0
15.4
193
1063
M23
ICD-10 Finland
Internal derangement of knee
3.8
15.1
47
129
S83.4
ICD-10 Finland
Sprain and strain involving (fibular)(tibial) collateral ligament of knee
3.3
15.1
58
183
WW200, ,
SPAT
1.7
15.0
355
2381
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
14.7
306
1977
ZXA05
NOMESCO Finland
Left side
1.8
14.7
260
1601
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
14.6
166
881
NBG10
NOMESCO Finland
Acromioplastia
4.2
14.5
39
96
L08
ICPC
Shoulder symptom/complaint
1.8
14.2
281
1784
N02AA05
ATC
oxycodone; systemic
1.9
13.9
187
1051
NGE15
NOMESCO Finland
Incision fo capsule of knee joint, arthroscopic
24.1
13.8
19
8
ZXA00
NOMESCO Finland
Right side
1.7
13.2
274
1761
WX111
NOMESCO Finland
Local infiltration anesthesia
3.1
13.0
55
184
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.4
13.0
93
409
NG1AA, ,
SPAT
2.2
13.0
123
609
M02AA07
ATC
piroxicam; topical
1.6
12.7
379
2676
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.4
12.7
93
413
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
12.7
320
2165
M25.2
ICD-10 Finland
Flail joint
5.0
12.7
27
55
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.4
12.6
85
364
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
12.4
186
1082
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.3
399
2870
M03BX02
ATC
tizanidine; oral
1.6
12.3
715
5908
B01AX06
ATC
[U] rivaroxaban
4.0
12.3
34
86
S93.2
ICD-10 Finland
Rupture of ligaments at ankle and foot level
4.8
12.2
27
57
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
12.1
228
1420
NF1AA
NOMESCO Finland
Hip X-ray examination
2.3
11.9
97
451
M70.6
ICD-10 Finland
Trochanteric bursitis
1.9
11.9
161
906
NHE20
NOMESCO Finland
Plastic repair of capsule or ligament of ankle joint with transplant
16.6
11.7
18
11
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.3
11.6
44
138
1223
FHL
Arthroscopy and articular cartilage surgery
5.1
11.5
24
48
M01AX17
ATC
nimesulide; oral
1.7
11.5
255
1661
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
11.5
122
630
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
4.9
11.5
25
52
R4110, ,
SPAT
1.9
11.4
162
924
XG410
NOMESCO Finland
Flow-volume spirometry
2.9
11.4
53
188
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
11.3
130
690
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
11.2
622
5029
M02AA10
ATC
ketoprofen; topical
1.8
11.1
176
1039
J01DB01
ATC
cefalexin; oral
1.8
11.0
900
7969
M77.1
ICD-10 Finland
Lateral epicondylitis
2.1
11.0
114
584
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.6
10.8
63
251
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
10.8
742
6269
WZA90
NOMESCO Finland
Other medical or dental certificate
1.7
10.8
264
1761
H02AB06
ATC
prednisolone; systemic
1.5
10.8
506
3932
H02BX01
ATC
methylprednisolone, combinations; systemic
2.8
10.7
54
200
M01AH02
ATC
rofecoxib; oral
1.9
10.7
136
748
R05FA02
ATC
opium derivatives and expectorants; systemic
1.6
10.7
413
3072
J01AA02
ATC
doxycycline; systemic
1.7
10.7
848
7409
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.8
10.7
52
189
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
3.3
10.6
39
120
M01AB08
ATC
etodolac; oral
2.2
10.6
89
419
ZXD20
NOMESCO Finland
Day surgery
1.9
10.6
147
832
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
10.5
217
1383
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
10.4
53
197
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
3.1
10.4
43
142
M93.2
ICD-10 Finland
Osteochondritis dissecans
+∞
10.4
10
*
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
3.1
10.4
42
137
M75.2
ICD-10 Finland
Bicipital tendinitis
3.3
10.3
38
117
NG1BG, ,
SPAT
2.5
10.3
65
270
M01AC01
ATC
piroxicam; systemic, rectal
1.9
10.1
140
791
SPAT1153
SPAT
Removal of sutures
1.6
10.1
322
2287
EB1VA, ,
NOMESCO Finland
1.7
9.9
216
1394
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
4.2
9.9
26
63
T93.3
ICD-10 Finland
Sequelae of dislocation, sprain and strain of lower limb
7.7
9.9
22
29
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
2.8
9.9
49
180
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
4.4
9.8
24
55
1222
FHL
Arthroscopy and synovial surgery
7.5
9.7
22
30
WX002
NOMESCO Finland
Sedation and analgesia
1.7
9.7
196
1239
M01AB55
ATC
diclofenac, combinations; oral
2.3
9.7
74
335
SFA10
NOMESCO Finland
One-surface restoration
1.5
9.6
609
4993
A02BC02
ATC
pantoprazole; systemic
1.5
9.6
730
6219
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
9.6
801
6966
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
3.7
9.6
30
83
W19
ICD-10 Finland
Unspecified fall
2.0
9.6
105
548
OAB93, ,
SPAT
2.1
9.6
94
471
SFA20
NOMESCO Finland
Two-surface restoration
1.5
9.4
658
5496
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.5
9.3
350
2569
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
9.3
783
6795
M01AE11
ATC
tiaprofenic acid; oral, rectal
2.7
9.2
48
181
B01AB05
ATC
enoxaparin; parenteral
1.5
9.2
316
2276
00000, ,
ICD-8 Finland
5.1
9.1
19
38
J01FA10
ATC
azithromycin; systemic
1.5
9.0
628
5218
M22.3
ICD-10 Finland
Other derangements of patella
15.7
9.0
14
9
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.2
9.0
74
346
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
9.0
285
2014
M89.0
ICD-10 Finland
Algoneurodystrophy
24.2
8.9
12
5
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.4
8.8
31
93
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.0
8.8
101
536
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
8.8
566
4624
M01AE01
ATC
ibuprofen; systemic, rectal
2.0
8.8
997
9245
S80.0
ICD-10 Finland
Contusion of knee
2.0
8.6
94
491
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.2
8.6
33
105
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
8.5
246
1697
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
8.5
101
542
R06AE07
ATC
cetirizine; oral
1.5
8.4
467
3694
R52.9
ICD-10 Finland
Pain, unspecified
1.9
8.4
116
656
R51.80
ICD-10 Finland
Headache
1.7
8.3
175
1116
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
8.3
200
1321
L03
ICPC
Low back symptom/complaint
1.5
8.3
315
2310
Z01.2
ICD-10 Finland
Dental examination
1.5
8.2
504
4060
N03AX12
ATC
[U] gabapentin; oral
1.7
8.2
175
1121
WZA00
NOMESCO Finland
Concise certificate
2.1
8.1
82
415
RF210, ,
NOMESCO Finland
2.9
8.1
37
130
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
8.1
125
730
L13
ICPC
Hip symptom/complaint
1.6
8.0
201
1339
NBL05
NOMESCO Finland
Arthroscopic suture or reinsertation of rotator cuff of shoulder
3.7
8.0
25
69
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.0
8.0
89
467
NGT60
NOMESCO Finland
Forcible manipulation of knee joint
4.3
8.0
20
47
R03AC02
ATC
salbutamol; inhalant
1.4
7.9
593
4943
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
7.9
200
1336
M79.1
ICD-10 Finland
Myalgia
1.7
7.9
173
1116
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
7.8
469
3750
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
7.8
85
443
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.7
503
4083
J01FF01
ATC
clindamycin; systemic
1.5
7.7
282
2048
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
7.6
470
3773
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
7.6
543
4475
R03BA05
ATC
fluticasone; inhalant
1.6
7.6
191
1273
SPAT1211
SPAT
Application of soft bandage
2.0
7.5
85
449
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.6
7.5
42
165
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
7.5
106
604
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.2
7.4
28
88
S18
ICPC
Laceration/cut
1.4
7.4
485
3931
N05CF01
ATC
zopiclone; oral
1.5
7.3
318
2385
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.0
7.3
80
418
SFA30
NOMESCO Finland
Three-surface restoration
1.4
7.2
472
3817
R01AD09
ATC
mometasone; nasal
1.4
7.2
498
4069
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.7
7.1
122
736
G47.3
ICD-10 Finland
Sleep apnoea
1.5
7.1
261
1893
M22.2
ICD-10 Finland
Patellofemoral disorders
8.8
7.1
14
16
M01AG02
ATC
tolfenamic acid; oral, rectal
1.6
7.0
173
1146
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.2
7.0
58
272
N02BF01
ATC
gabapentin; oral
1.7
7.0
118
709
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
6.9
160
1043
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.7
6.9
138
867
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
2.8
6.9
34
125
M16.1
ICD-10 Finland
Other primary coxarthrosis
1.8
6.9
110
649
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
6.7
253
1841
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.7
363
2830
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.7
547
4578
D07AC01
ATC
betamethasone; topical
1.4
6.7
365
2850
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.1
6.7
59
285
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
2.6
6.6
37
146
J02AC01
ATC
fluconazole; systemic
1.4
6.6
417
3340
9271
FHL
Hallux surgery
3.9
6.6
19
50
Y79.2
ICD-10 Finland
Orthopaedic devices associated with adverse incidents, prosthetic and other implants, materials and accessory devices
10.1
6.5
12
12
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
6.5
111
667
WX212
NOMESCO Finland
Femoral plexus blockade
3.1
6.5
27
90
N06AX21
ATC
duloxetine; oral
1.7
6.5
136
864
S20.2
ICD-10 Finland
Contusion of thorax
2.1
6.5
58
281
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
3.1
6.5
26
85
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
3.4
6.4
22
65
M67.2
ICD-10 Finland
Synovial hypertrophy, not elsewhere classified
14.4
6.4
10
7
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
6.4
116
710
9243
FHL
Plastic of the patella and its tendons
3.8
6.4
19
51
M75
ICD-10 Finland
Shoulder lesions
2.1
6.4
55
263
NGB10
NOMESCO Finland
Primary partial prosthetic replacement of knee joint, demi prosthesis
5.6
6.3
17
31
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
1.7
6.3
120
745
K02.1
ICD-10 Finland
Caries of dentine
1.4
6.3
631
5439
Z04.3
ICD-10 Finland
Examination and observation following other accident
3.0
6.3
26
87
XA402
NOMESCO Finland
ENMG
2.7
6.2
31
115
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
6.2
123
772
R05
ICD-10 Finland
Cough
1.5
6.2
223
1607
S63.6
ICD-10 Finland
Sprain and strain of finger(s)
2.3
6.1
46
208
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.3
6.1
43
189
A02BC03
ATC
lansoprazole; oral
1.4
6.1
284
2148
M02AA15
ATC
diclofenac; topical
1.9
6.1
77
423
M15
ICD-10 Finland
Polyarthrosis
2.1
6.1
57
282
R01AD08
ATC
fluticasone; nasal
1.4
6.0
302
2314
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.1
6.0
57
283
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.6
6.0
148
980
H02AB07
ATC
prednisone; oral
1.6
6.0
130
834
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
278
1172
2.85
45.05
5.0
4.7
31.24
31.92
%
0.41
162
795
112
418
2.87
21.90
3.0
3.0
1.02
1.02
ratio
0.43
107
387
42
95
4.56
17.41
2.5
2.3
29.93
24.01
mg/l
0.31
15
40
360
2374
1.77
16.39
2.0
2.3
—
—
—
0
0
318
2028
1.80
16.18
1.4
1.3
31.63
30.99
iu/ml
0.04
111
636
294
1881
1.77
14.56
1.4
1.3
8.45
13.10
u/ml
0.67
106
769
848
7265
1.77
13.28
5.8
4.4
9.85
11.15
mm/h
2.73
790
6845
68
254
2.79
13.24
2.0
1.5
7381.05
12432.50
e6/l
0.88
55
181
79
328
2.52
12.48
2.9
3.8
25.06
24.90
mmol/l
0.22
73
309
54
186
3.00
12.18
4.4
3.5
25.51
23.62
mg/l
0.17
39
123
580
4582
1.57
11.88
2.8
2.7
—
—
estimate
—
0
0
539
4215
1.56
11.35
9.1
11.5
1.15
1.18
inr
1.00
432
3465
418
3161
1.53
9.83
2.4
2.5
55.99
60.92
u/l
0.83
388
2951
64
276
2.40
9.35
1.8
1.3
—
—
—
0
0
795
6917
1.56
9.35
3.8
3.4
49.23
47.79
u/l
0.15
749
6582
459
3572
1.49
9.25
3.9
3.4
33.61
55.64
ng/l
0.59
308
2402
114
624
1.92
9.07
2.6
3.5
5.26
5.12
kpa
1.38
106
606
129
736
1.85
9.04
2.8
2.5
29.61
21.31
au/ml
0.50
17
84
31
92
3.44
8.95
1.4
1.3
16093.80
137588.05
e6/l
0.90
20
62
204
1373
1.60
7.81
2.6
2.5
166.87
107.39
ug/g
1.66
172
1114
66
314
2.17
7.70
1.4
1.3
—
—
—
0
0
115
672
1.80
7.45
1.5
1.3
52.55
40.38
au/ml
—
6
58
27
83
3.31
7.42
1.3
1.1
—
43.20
—
0
5
95
528
1.88
7.23
2.7
3.4
1.42
1.69
mmol/l
0.37
74
396
341
2612
1.45
6.98
2.4
2.7
333.75
335.71
umol/l
0.15
289
2355
158
1047
1.60
6.40
4.0
6.3
—
—
—
0
0
600
5139
1.38
6.16
6.0
6.9
10.92
11.28
umol/l
0.40
563
4935
1025
9771
1.93
5.64
16.9
17.0
3.96
3.96
mmol/l
0.32
1002
9583
1023
9750
1.90
5.57
16.8
16.8
139.85
139.75
mmol/l
0.73
1004
9583
50
955
0.50
5.56
3.4
3.1
—
—
—
0
0
1003
9506
1.75
5.53
16.0
14.8
19.44
22.75
mg/l
2.63
852
7780
29
111
2.66
5.51
1.5
1.5
51.68
57.18
%
0.28
22
72
40
179
2.28
5.47
3.1
3.2
7.26
7.30
mmol/l
0.04
40
174
55
280
2.02
5.45
1.2
1.1
3.54
3.92
—
9
40
549
4704
1.34
5.28
7.1
7.4
1.22
1.21
mmol/l
3.83
481
4083
641
5643
1.33
5.01
4.4
5.0
6.55
6.64
mmol/l
0.64
612
5346
986
9340
1.63
4.97
13.4
14.0
84.26
83.85
ml/min/173m2
0.29
912
8650
645
5692
1.33
4.91
8.4
10.0
4.27
4.01
e9/l
0.52
573
5006
818
7485
1.38
4.87
8.8
8.4
77.36
78.22
u/l
0.23
778
7147
30
126
2.42
4.76
1.2
1.5
—
—
—
0
0
30
126
2.42
4.76
1.2
1.5
—
—
—
0
0
1049
10133
2.16
4.72
13.3
12.1
26.85
26.70
u/l
0.10
1016
9896
30
127
2.40
4.68
1.2
1.5
—
—
—
0
0
327
2633
1.35
4.64
2.7
3.1
807.30
955.89
ng/l
0.24
255
2231
20
69
2.93
4.62
1.1
1.0
—
—
—
0
0
11
19
5.84
4.45
1.4
1.4
0.49
0.33
ug/l
—
6
14
1051
10176
2.15
4.42
20.1
18.9
73.70
74.98
umol/l
1.15
1035
10079
30
132
2.31
4.32
1.2
1.4
—
—
—
0
0
30
134
2.27
4.18
1.2
1.4
—
—
—
0
0
30
134
2.27
4.18
1.2
1.4
—
—
—
0
0
135
1850
0.69
3.92
2.7
2.9
2.43
2.44
mmol/l
0.53
111
1680
514
4498
1.27
3.73
2.7
2.5
75.61
76.44
nmol/l
0.30
444
4140
483
4206
1.27
3.61
5.3
6.7
1.22
1.21
mmol/l
3.71
432
3914
281
2292
1.31
3.51
1.7
1.8
0.90
1.13
mg/l
0.49
206
1786
945
8982
1.41
3.50
6.0
5.4
1.73
1.88
mu/l
4.38
869
8409
58
349
1.70
3.49
1.6
1.5
0.09
0.05
iu/ml
—
9
51
476
4158
1.26
3.41
2.2
2.0
100.97
96.88
pmol/l
1.06
265
2222
13
38
3.45
3.31
2.5
2.4
—
—
—
0
0
117
840
1.44
3.27
2.7
2.3
13.55
13.25
nmol/l
0.16
102
767
1066
10442
2.41
3.24
24.3
22.7
6.88
6.64
e9/l
0.53
1047
10235
16
60
2.69
3.23
1.5
1.3
156.09
159.91
pmol/l
0.05
16
60
351
2976
1.27
3.19
2.2
2.2
201.53
227.54
u/l
0.14
332
2826
958
9162
1.40
3.09
7.5
6.0
39.02
38.96
mmol/mol
0.08
891
8662
10
25
4.03
3.09
1.1
1.0
—
—
—
0
0
35
188
1.89
3.09
2.1
2.2
5.40
5.21
mmol/24h
0.11
28
165
1065
10437
2.30
3.07
24.3
22.7
257.66
254.10
e9/l
1.09
1049
10261
52
316
1.68
3.05
1.3
1.2
6.59
8.30
u/ml
—
9
48
1065
10439
2.29
3.04
24.2
22.6
91.14
91.03
fl
0.38
1053
10346
52
317
1.67
3.02
1.3
1.2
1.80
2.36
u/ml
—
5
28
1065
10441
2.27
3.00
24.2
22.6
4.53
4.52
e12/l
0.24
1048
10238
1065
10441
2.27
3.00
24.5
23.1
39.38
40.69
%
5.54
1053
10344
68
445
1.56
2.98
1.4
2.0
5.66
7.94
iu/ml
0.25
12
111
1065
10445
2.25
2.92
24.5
22.8
137.23
136.30
g/l
1.43
1053
10353
49
298
1.67
2.88
1.3
1.3
—
—
—
0
0
189
1498
1.32
2.88
2.7
3.0
2.90
2.61
e6/l
0.18
113
713
11
33
3.36
2.81
3.1
1.5
—
—
—
0
0
15
60
2.52
2.71
1.8
3.3
687.87
688.20
u/ml
0.00
15
60
53
336
1.61
2.67
1.2
1.2
—
37.12
—
0
15
23
113
2.06
2.63
1.2
1.1
—
—
—
0
0
58
380
1.56
2.56
1.5
2.2
7.72
7.35
g/l
0.65
49
363
960
9239
1.35
2.49
5.0
4.3
1.30
1.31
mmol/l
0.06
885
8620
12
45
2.69
2.45
1.3
2.2
—
—
—
0
0
43
265
1.65
2.44
1.3
1.3
537.19
509.59
mg/l
0.09
43
251
6
12
5.02
2.40
2.5
2.3
—
—
—
0
0
6
12
5.02
2.40
2.2
2.3
—
—
—
0
0
52
339
1.56
2.36
1.5
1.9
—
—
—
0
0
57
380
1.53
2.35
1.5
2.2
4.18
4.29
g/l
0.51
49
363
57
380
1.53
2.35
1.5
2.2
3.62
3.75
g/l
0.33
49
363
50
325
1.56
2.31
1.4
2.2
10.66
10.26
g/l
0.19
41
307
48
310
1.57
2.28
1.5
1.8
—
—
—
0
0
16
72
2.24
2.28
1.1
1.6
5.05
6.15
ug/l
0.85
16
62
54
360
1.53
2.24
1.6
2.2
2.84
2.89
g/l
0.10
45
343
679
6320
1.20
2.21
3.2
3.1
—
—
—
0
0
104
787
1.36
2.19
2.3
2.4
0.24
0.29
e6/l
0.18
104
747
254
2159
1.23
2.17
1.5
1.5
2.29
2.40
g/l
0.52
170
1382
95
712
1.37
2.13
3.0
4.2
67.51
85.66
ng/l
2.09
73
645
995
9662
1.37
2.13
5.9
5.0
1.47
1.47
mmol/l
0.13
924
9062
962
9308
1.30
2.01
5.8
5.0
5.92
5.90
mmol/l
0.19
872
8682
995
9683
1.34
1.90
5.9
5.1
4.75
4.72
mmol/l
0.35
926
9142
55
384
1.46
1.87
1.6
1.6
16.26
10.58
u/ml
—
5
90
136
1097
1.27
1.84
1.8
2.0
—
—
—
0
0
5
12
4.18
1.82
1.4
1.5
—
—
—
0
0
12
54
2.24
1.74
1.5
1.1
—
—
—
0
0
165
1375
1.24
1.70
1.8
1.7
904.41
1186.76
nmol/l
4.72
117
1063
277
2434
1.19
1.65
1.4
1.3
1.96
1.57
u/ml
0.17
80
716
28
173
1.63
1.65
1.5
1.3
29.16
28.65
u/l
0.02
23
143
124
1004
1.27
1.65
1.7
1.9
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
251
0.51
1.64
1.7
3.1
0.40
0.38
iu/ml
—
6
130
84
1077
0.76
1.62
1.9
1.9
—
—
—
0
0
191
1625
1.21
1.62
2.7
2.8
0.73
1.04
e6/l
1.03
116
836
5
14
3.58
1.61
1.0
1.1
—
—
—
0
0
12
56
2.16
1.61
1.0
1.3
—
—
—
0
0
64
474
1.37
1.60
2.7
2.2
42.71
39.86
u/l
0.49
59
431
70
527
1.35
1.58
1.1
1.1
—
—
—
0
0
96
757
1.29
1.58
2.8
2.9
66.96
67.05
g/l
0.05
83
715
17
92
1.86
1.56
2.4
2.6
104.53
105.58
mmol/l
0.44
17
92
17
92
1.86
1.56
2.4
2.6
4.08
4.00
mmol/l
0.57
17
92
126
1032
1.25
1.53
3.3
4.6
220.63
252.74
u/l
2.44
120
984
20
115
1.75
1.53
1.2
1.1
—
—
—
0
0
513
4755
1.15
1.51
3.0
3.1
108.46
118.66
ug/l
0.83
484
4499
30
194
1.56
1.49
1.6
1.5
—
—
—
0
0
386
3508
1.16
1.49
2.7
3.4
31.53
31.83
u/l
0.06
371
3337
149
1248
1.22
1.48
2.0
2.0
3.32
3.49
ratio
1.08
118
987
13
66
1.98
1.43
1.0
1.0
0.95
1.13
u/l
—
6
35
301
3345
0.86
1.42
3.5
3.7
2.37
2.35
mmol/l
1.04
263
3083
44
313
1.42
1.41
2.4
2.8
—
—
—
0
0
29
192
1.52
1.33
1.1
1.1
18.31
18.17
au/ml
—
8
55
44
317
1.40
1.33
1.4
1.5
308.08
299.55
ug/g
0.11
33
187
26
168
1.56
1.32
1.1
1.1
—
—
—
0
0
317
2863
1.15
1.32
6.3
5.1
2.26
2.16
ug/l
0.14
280
2608
56
732
0.75
1.28
3.0
3.7
1.23
1.23
mmol/l
0.15
50
629
45
328
1.39
1.28
1.8
2.3
1.09
0.92
g/l
0.08
35
302
11
55
2.01
1.27
1.8
1.8
74.06
102.08
ng/l
0.68
11
55
102
836
1.24
1.26
2.7
2.8
11.09
10.60
g/l
0.25
95
785
16
92
1.75
1.25
2.5
2.6
1.19
1.19
mmol/l
0.05
16
92
8
160
0.50
1.25
1.1
1.4
—
—
—
0
0
8
160
0.50
1.25
1.1
1.4
—
—
—
0
0
15
253
0.59
1.25
1.9
1.5
—
—
—
0
0
50
373
1.36
1.24
1.5
1.6
254.68
297.24
mu/l
0.91
50
347
13
70
1.87
1.24
2.7
2.3
258.77
214.71
e6/l
0.27
13
62
17
100
1.71
1.24
1.2
2.0
—
—
—
0
0
24
155
1.56
1.23
1.0
1.1
1.52
2.03
eliau/ml
0.30
13
74
37
264
1.42
1.20
2.4
3.3
30.63
2.30
ratio
0.47
27
149
83
1019
0.80
1.18
5.9
9.1
-0.06
0.84
mmol/l
1.43
69
856
16
94
1.71
1.17
1.4
1.1
—
—
—
0
0
16
94
1.71
1.17
1.4
1.1
—
—
—
0
0
295
2675
1.14
1.15
1.7
1.7
19.78
20.69
nmol/l
0.49
237
2299
23
150
1.54
1.15
2.9
3.7
1.29
1.72
%
0.21
17
137
18
111
1.63
1.12
1.3
1.5
33.92
25.39
ng/l
0.28
18
111
796
7680
1.14
1.10
4.8
4.5
14.94
14.62
pmol/l
3.10
721
7156
18
112
1.62
1.09
1.4
1.2
—
—
—
0
0
206
2310
0.87
1.08
3.7
3.5
0.11
0.12
0.01
18
17
448
4183
1.12
1.08
5.1
5.2
36.87
36.18
g/l
2.22
422
3971
15
89
1.70
1.08
1.5
1.1
—
—
—
0
0
33
239
1.39
1.01
1.3
1.1
1.49
2.04
u/ml
0.29
17
132
15
91
1.66
1.01
3.1
2.6
—
—
—
0
0
9
48
1.88
1.00
1.2
1.1
103.19
232.70
iu/ml
—
9
48
25
172
1.46
1.00
1.4
1.2
7.80
6.39
u/ml
—
10
69
16
99
1.63
1.00
1.4
1.1
—
—
—
0
0
116
990
1.19
1.00
2.1
2.1
356.47
377.22
nmol/l
0.54
106
924
197
1755
1.15
1.00
3.7
3.1
0.67
0.73
ug/l
0.73
121
1066
316
2907
1.12
0.97
3.5
3.0
0.01
0.06
estimate
0.67
68
848
15
92
1.64
0.97
1.5
1.1
—
—
—
0
0
39
293
1.34
0.97
1.3
1.3
9.62
10.36
u/l
0.14
34
243
9
50
1.81
0.96
1.0
1.3
221.22
475.16
u/l
—
9
45
188
2102
0.87
0.95
2.5
2.6
5.39
5.85
e6/l
0.22
173
1929
647
6195
1.11
0.94
4.7
4.2
64.00
716.06
e6/l
—
6
85
6
27
2.23
0.93
1.2
1.1
—
—
—
0
0
109
932
1.19
0.93
1.6
1.8
3.48
3.52
mmol/l
0.10
75
673
77
637
1.22
0.92
2.8
3.8
4.55
4.55
pmol/l
0.01
67
568
20
134
1.50
0.92
1.2
1.4
0.77
0.60
nmol/l
0.31
20
126
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
80
666
1.22
0.91
1.6
1.6
—
—
—
0
0
6
29
2.07
0.89
1.3
1.2
—
—
—
0
0
31
414
0.74
0.88
1.5
1.5
—
—
—
0
0
91
772
1.20
0.86
1.6
1.5
—
—
—
0
0
260
2826
0.89
0.84
3.5
3.8
0.00
0.01
estimate
1.54
82
993
552
5267
1.10
0.82
4.3
3.6
0.05
0.32
estimate
0.42
100
994
994
9794
1.18
0.79
6.2
5.7
2.82
2.78
mmol/l
0.52
919
9213
11
175
0.62
0.78
1.1
1.6
—
—
—
0
0
74
622
1.20
0.78
1.5
1.3
24.91
28.99
iu/l
0.64
67
536
15
99
1.52
0.76
1.2
1.1
—
—
—
0
0
17
116
1.47
0.74
1.1
1.1
—
—
—
0
0
14
92
1.53
0.72
1.1
2.0
—
—
—
0
0
14
92
1.53
0.72
1.4
1.1
27.32
16.28
u/ml
—
5
44
204
1864
1.12
0.72
1.6
1.5
—
—
—
0
0
262
2427
1.10
0.71
2.3
2.2
2.66
2.77
mg/l
0.50
225
2105
16
110
1.46
0.68
1.3
1.3
—
—
—
0
0
5
27
1.86
0.68
1.0
1.2
—
—
—
0
0
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
15
102
1.48
0.67
5.0
3.5
—
—
—
0
0
7
121
0.58
0.67
1.7
1.9
—
—
—
0
0
5
28
1.79
0.66
1.4
1.2
—
—
—
0
0
11
70
1.58
0.65
2.5
2.2
629.09
587.02
e6/l
0.08
11
58
54
450
1.21
0.65
4.6
4.0
44.28
48.76
%
0.61
54
442
15
213
0.70
0.65
1.4
1.4
—
—
—
0
0
209
1924
1.11
0.65
1.6
1.7
402.19
24586572.33
pmol/l
1.67
177
1631
20
146
1.38
0.64
1.2
1.1
0.06
0.10
u/ml
—
6
47
23
174
1.33
0.60
1.2
1.2
1.38
3.96
u/ml
—
8
54
15
105
1.43
0.60
1.5
1.2
—
—
—
0
0
31
245
1.27
0.60
1.3
1.5
88.00
165.92
pmol/l
0.71
31
240
8
52
1.54
0.59
1.1
1.2
12.25
9.04
mm/h
—
8
52
0
22
0.00
0.59
0.0
1.9
—
7.58
—
0
13
72
623
1.17
0.59
1.8
1.9
—
—
—
0
0
101
1131
0.88
0.57
1.8
1.8
—
—
—
0
0
8
55
1.46
0.56
1.4
1.1
—
—
—
0
0
56
478
1.18
0.55
1.4
1.5
—
—
—
0
0
28
223
1.26
0.52
5.4
6.4
102.20
222.73
iu/ml
—
5
30
6
96
0.62
0.52
1.2
1.0
—
—
—
0
0
26
206
1.27
0.51
1.2
1.1
3.88
4.56
u/ml
0.09
12
102
35
288
1.22
0.50
1.5
2.2
0.00
0.02
g/l
0.50
30
268
105
946
1.12
0.50
3.3
4.6
55.82
15.61
ug/l
0.53
88
768
6
41
1.47
0.50
2.5
2.0
—
350.33
—
0
6
25
198
1.27
0.49
1.2
1.1
0.23
1.38
u/ml
—
9
98
19
145
1.32
0.49
1.2
1.1
—
—
—
0
0
39
327
1.20
0.48
1.2
1.3
—
—
—
0
0
125
1142
1.11
0.47
3.4
2.8
7.29
7.73
umol/l
0.11
118
1016
22
276
0.79
0.46
2.2
3.9
1.63
1.32
mmol/l
0.77
22
268
8
119
0.67
0.46
1.8
1.9
—
—
—
0
0
43
366
1.18
0.45
1.8
1.7
—
—
—
0
0
11
77
1.43
0.45
3.6
2.4
49.80
38.15
mg/l
—
5
55
23
183
1.26
0.45
2.2
4.1
22.13
356.66
u/ml
1.61
23
173
12
162
0.74
0.42
1.4
2.0
—
—
—
0
0
5
33
1.52
0.41
1.8
1.3
9.41
8.42
ug/l
—
5
33
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
421
4360
0.94
0.41
1.8
1.9
1.51
1.37
mmol/l
2.23
358
3730
0
17
0.00
0.40
0.0
1.8
—
1.24
—
0
17
31
368
0.84
0.40
1.4
1.6
1050.85
1001.73
mu/l
0.10
19
294
0
18
0.00
0.40
0.0
1.3
—
1.18
—
0
18
237
2497
0.93
0.40
3.7
4.0
93.04
92.47
%
0.14
229
2450
17
214
0.79
0.38
1.4
1.4
0.94
1.21
ratio
—
7
130
17
214
0.79
0.38
1.4
1.4
1.06
0.95
ratio
—
7
130
17
214
0.79
0.38
1.4
1.4
1.61
1.16
ratio
—
7
130
5
37
1.35
0.37
1.4
1.1
24.18
37.31
u/ml
—
5
37
8
116
0.69
0.37
1.4
1.5
45.18
52.98
ug/l
—
8
116
60
536
1.13
0.36
1.4
1.7
—
—
—
0
0
16
200
0.80
0.34
1.4
1.5
152.00
156.56
au/ml
—
5
57
6
44
1.37
0.34
1.2
1.1
5.20
6.11
umol/l
—
6
37
171
1809
0.94
0.33
3.2
3.7
37.27
394.65
ng/l
6.65
106
1330
6
46
1.31
0.33
1.7
1.3
—
—
—
0
0
6
46
1.31
0.33
1.7
1.3
—
—
—
0
0
167
1577
1.07
0.32
2.4
2.6
14.25
13.65
umol/l
0.48
156
1475
125
1336
0.93
0.32
1.8
1.9
1.49
1.47
%
0.12
112
1177
11
83
1.33
0.32
1.3
1.6
1.40
1.11
promille
0.29
11
67
19
228
0.83
0.29
1.3
1.5
57.15
59.60
ug/l
0.07
11
184
67
732
0.91
0.29
1.8
2.3
6.71
7.22
ug/l
0.09
52
665
101
941
1.08
0.29
2.6
2.5
32.53
43.20
u/l
1.11
86
805
16
195
0.82
0.29
1.5
1.6
—
—
—
0
0
28
242
1.16
0.28
2.3
3.4
0.31
2.27
index
4.26
16
125
11
85
1.30
0.28
1.3
1.1
109.82
112.99
pmol/l
0.07
11
85
18
149
1.21
0.28
1.1
1.1
—
—
—
0
0
32
281
1.14
0.26
1.5
2.1
0.00
0.00
g/l
-0.00
27
251
5
71
0.70
0.26
1.8
2.5
553.60
623.94
ml
—
5
48
5
73
0.68
0.26
1.6
1.3
70.40
76.95
umol/l
—
5
73
13
160
0.81
0.26
1.8
1.6
—
—
—
0
0
38
339
1.13
0.25
2.5
2.0
1486.53
5419.15
u/l
—
9
132
55
503
1.10
0.24
1.5
1.4
—
—
—
0
0
329
3196
1.04
0.24
4.4
4.1
4.37
7.98
mg/mmol
2.06
192
1990
5
39
1.28
0.23
1.2
1.2
0.31
0.29
g/l
—
5
33
23
200
1.15
0.22
1.4
1.5
—
—
—
0
0
10
79
1.27
0.22
1.4
1.4
—
—
—
0
0
12
146
0.82
0.22
2.2
1.7
—
—
—
0
0
36
324
1.11
0.22
1.4
1.7
0.26
0.24
g/l
0.89
36
310
5
41
1.22
0.22
1.0
2.6
—
818.17
—
0
6
5
42
1.19
0.21
1.0
1.1
—
86.83
—
0
6
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
21
182
1.16
0.21
1.3
1.2
23.83
21.85
u/l
0.07
16
157
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
33.16
—
0
8
0
13
0.00
0.21
0.0
2.3
—
—
—
0
0
526
5170
1.03
0.20
4.1
3.6
0.00
0.00
estimate
0.50
105
1042
157
1636
0.95
0.20
2.7
3.7
0.82
0.82
mmol/l
0.02
145
1561
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
9.4
—
5.34
—
0
14
26
231
1.13
0.19
1.2
1.5
631.29
1819.77
e6/l
0.41
21
175
6
53
1.13
0.18
1.7
1.3
—
—
—
0
0
6
53
1.13
0.18
1.7
1.3
—
—
—
0
0
15
128
1.17
0.18
1.1
1.5
—
—
—
0
0
32
352
0.91
0.18
1.4
1.3
178.29
235.22
miu/ml
0.37
14
166
14
119
1.18
0.17
1.1
1.3
0.16
0.18
nmol/l
—
9
90
530
5221
1.03
0.17
4.0
3.6
0.00
5.90
estimate
1.34
106
1066
7
61
1.15
0.17
2.0
1.4
—
—
—
0
0
5
68
0.73
0.17
1.6
1.5
2.60
7.14
u/l
—
5
56
29
263
1.11
0.16
1.3
1.3
—
—
—
0
0
9
79
1.14
0.15
1.0
1.2
—
—
—
0
0
9
80
1.13
0.15
1.0
1.2
—
—
—
0
0
33
304
1.09
0.14
2.3
2.1
16.04
4.17
iu/l
0.46
12
127
25
227
1.10
0.14
1.2
1.5
3.95
14.62
e6/l
1.27
19
166
169
1740
0.97
0.14
1.6
1.5
—
—
—
0
0
23
208
1.11
0.14
1.3
1.3
275.80
252.65
u/ml
—
10
126
139
1345
1.04
0.14
2.4
2.6
22.41
23.35
%
0.38
129
1260
22
243
0.90
0.14
1.8
1.8
—
—
—
0
0
40
373
1.08
0.13
1.4
1.5
—
—
—
0
0
52
491
1.06
0.13
1.7
1.6
0.32
0.35
mg/l
0.20
25
232
91
874
1.04
0.13
3.4
3.8
1.94
1.80
mmol/l
0.21
78
760
40
375
1.07
0.12
1.6
1.9
0.44
2.25
ug/l
1.59
33
342
15
168
0.89
0.11
1.1
1.3
—
—
—
0
0
22
202
1.09
0.10
1.6
1.6
—
—
—
0
0
151
1474
1.03
0.10
2.4
2.6
2.44
2.35
g/l
1.21
142
1377
5
47
1.06
0.09
1.0
1.2
—
—
—
0
0
78
807
0.96
0.09
3.8
2.6
72.63
68.87
ml/min/173m2
0.37
19
341
54
517
1.05
0.09
1.7
1.8
—
—
—
0
0
403
3985
1.02
0.09
3.8
3.4
0.01
0.03
estimate
0.73
81
868
234
2302
1.02
0.09
4.1
4.3
20.97
21.17
%
0.07
115
1031
6
58
1.03
0.08
1.0
1.2
49.33
17.43
u/l
—
6
47
5
60
0.83
0.08
1.0
1.2
72.00
84.02
u/l
—
5
50
5
64
0.78
0.08
12.8
12.4
0.52
0.64
mmol/l
—
5
57
129
1263
1.02
0.07
5.4
6.4
1.01
1.03
mmol/l
0.33
114
1177
8
94
0.85
0.06
1.3
1.2
—
—
—
0
0
225
2279
0.98
0.06
3.9
3.6
1.02
1.68
kg/l
0.50
176
1517
22
233
0.94
0.06
1.7
1.6
—
—
—
0
0
21
198
1.06
0.05
1.6
3.3
8.87
8.51
pmol/l
0.05
21
198
259
2613
0.99
0.04
3.2
3.1
0.14
0.37
e6/l
2.93
189
1913
46
447
1.03
0.04
1.1
1.2
0.88
0.90
g/l
0.28
46
447
27
259
1.04
0.04
1.1
1.2
—
—
—
0
0
13
121
1.08
0.03
1.2
1.3
—
—
—
0
0
22
230
0.96
0.03
1.5
2.3
129.56
131.81
g/l
0.14
16
181
78
768
1.02
0.03
1.1
1.2
161.54
144.83
u/ml
0.13
28
311
26
252
1.03
0.02
1.5
1.2
—
—
—
0
0
13
137
0.95
0.01
1.3
1.4
10.18
7.49
mmol/l
—
8
117
14
147
0.95
0.01
1.4
1.6
—
—
—
0
0
45
442
1.02
0.01
1.8
1.8
3.92
4.86
mg/l
0.26
33
331
22
213
1.03
0.01
1.4
1.6
—
—
—
0
0
44
433
1.02
0.01
1.1
1.1
1.54
1.56
g/l
0.18
44
433
10
94
1.06
0.01
1.3
1.8
—
—
—
0
0
10
106
0.94
0.01
1.0
1.3
49.30
49.78
u/l
—
10
95
41
404
1.02
0.00
1.0
1.1
0.41
0.68
ratio
—
5
48
38
384
0.99
0.00
1.2
1.9
1.55
1.49
g/l
0.14
27
341
26
258
1.01
0.00
1.5
1.7
—
—
—
0
0
304
3044
1.00
0.00
3.4
3.2
29.67
71.59
e6/l
1.07
235
2334
26
261
1.00
0.00
1.2
1.2
—
—
—
0
0
150
1505
1.00
0.00
1.8
1.9
—
—
—
0
0
5
56
0.89
0.00
1.2
1.2
32.20
29.94
umol/l
—
5
50
5
56
0.89
0.00
2.2
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.01
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
11.43
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.5
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
10.89
—
0
9
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
624.40
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
337
3370
1.00
-0.00
3.9
3.4
7.75
7.82
mmol/l
0.11
267
2902
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
13.32
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
-0.00
1.9
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.01
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
61
0.98
-0.00
1.3
1.2
1.09
1.06
ratio
—
6
53
0
7
0.00
-0.00
0.0
1.1
—
8.25
—
0
7
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
51
0.98
-0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
2.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
68
0.88
-0.00
1.7
1.9
—
—
—
0
0
26
260
1.00
-0.00
1.7
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_CHONDROMALACIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CHONDROMALACIA | 0.686 [0.57, 0.83] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.102 |
During the follow-up period (1.1.1998 — 31.12.2019), 116 out of 3100 females with M13_CHONDROMALACIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_CHONDROMALACIA | 0.576 [0.49, 0.68] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.087 |
During the follow-up period (1.1.1998 — 31.12.2019), 161 out of 2662 males with M13_CHONDROMALACIA died.
Mortality risk
Mortality risk for people of age
years, who have M13_CHONDROMALACIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.059% | 0.107% |
| 5 | 0.404% | 0.732% |
| 10 | 0.936% | 1.884% |
| 15 | 1.833% | 3.6% |
| 20 | 3.238% | 6.105% |
Relationships between endpoints
↥Index endpoint: M13_CHONDROMALACIA – Chondromalacia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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