brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
235 |
4. Check minimum number of eventsNone |
235 |
5. Include endpointsNone |
235 |
6. Filter based on genotype QC (FinnGen only) |
217 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D33
- Name in latin
- Neoplasma benignum cerebri infratentoriale
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Brain, infratentorial
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1554 | 828 | 719 |
| Only index persons | 1386 | 743 | 643 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 44.15 | 46.77 | 40.95 |
| Only index persons | 43.19 | 45.75 | 40.23 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 217 | 133 | 84 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | 48.58 | 47.51 | 50.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 224
- Matched controls
- 2240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
25.5
140.7
139
135
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
246.0
117.4
112
9
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
55.3
82.4
48
11
D33.10
ICD-10 Finland
Benign pilosytic astrocytoma of brain stem
+∞
71.8
65
*
D33.14
ICD-10 Finland
Hemangioblastoma and cerebellum
+∞
61.3
56
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
17.6
55.4
49
35
D33.15
ICD-10 Finland
Another benign tumor of the cerebellum
+∞
53.3
49
*
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
+∞
46.5
43
*
D33.11
ICD-10 Finland
Brain stem
+∞
46.5
43
*
D33.12
ICD-10 Finland
Cerebellum
+∞
37.6
35
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
146.9
35.9
37
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.8
33.3
83
208
C71.60
ICD-10 Finland
Malignant tumor of cerebellum without histology
+∞
32.0
30
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
6.1
29.2
62
133
D33.1
ICD-10 Finland
Benign neoplasm: Brain, infratentorial
+∞
25.5
24
*
9421/1-C71.6
ICD-O-3
Pilocytic astrocytoma of cerebellum, NOS
+∞
21.2
20
*
H02AB02
ATC
dexamethasone; systemic
4.7
21.0
59
158
AA1AD
NOMESCO Finland
CT of head and brain
3.8
20.9
103
414
G91.1
ICD-10 Finland
Obstructive hydrocephalus
115.3
19.9
21
*
XA800
NOMESCO Finland
Neuropsychological investigation
6.6
19.5
34
59
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
24.3
18.7
26
12
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
+∞
15.8
15
*
D33.17
ICD-10 Finland
Fourth ventricle
+∞
15.8
15
*
H53.2
ICD-10 Finland
Diplopia
7.2
14.8
23
35
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
148.6
13.6
14
*
XCK00
NOMESCO Finland
Perimetry
5.0
13.0
30
67
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
12.7
85
389
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
74.2
12.7
14
*
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
+∞
12.6
12
*
Q85.82
ICD-10 Finland
of Hipple-Lindau syndrome
+∞
12.6
12
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
12.4
66
266
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
22.8
12.2
17
8
AAF00
NOMESCO Finland
Ventriculostomy
49.5
12.0
14
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.4
11.9
51
180
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
20.3
11.8
17
9
D33.42
ICD-10 Finland
Hemangioblastoma of the spinal cord
+∞
11.6
11
*
ZXD05
NOMESCO Finland
Urgent procedure
2.7
11.1
89
442
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
16.6
11.0
17
11
G93.0
ICD-10 Finland
Cerebral cysts
63.1
10.7
12
*
R51.80
ICD-10 Finland
Headache
2.8
10.3
65
284
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.5
10.3
40
132
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
10.0
67
302
ZXC95
NOMESCO Finland
Use of surgical navigator
22.9
9.5
13
6
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.5
9.4
24
58
D32.05
ICD-10 Finland
Cerebral meninges
+∞
9.4
9
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
38.4
9.1
11
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
13.3
9.0
15
12
N76
ICPC
Neoplasm nervous system unspecified
52.1
8.7
10
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.1
8.6
25
67
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
28.8
8.6
11
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
13.5
8.5
14
11
ZXD35
NOMESCO Finland
Usual procedure
7.0
8.4
20
31
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
+∞
8.4
8
*
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
+∞
8.4
8
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
15.2
8.3
13
9
D33.30
ICD-10 Finland
Acoustic neuroma
23.0
8.1
11
5
N03AX14
ATC
levetiracetam; systemic
8.3
8.0
17
22
WX882
NOMESCO Finland
High dependency care
6.9
7.6
18
28
ZXD10
NOMESCO Finland
Scheduled procedure
2.2
7.4
98
587
AA1BD
NOMESCO Finland
Extensive CT of head and brain
7.7
7.3
16
22
C71.6
ICD-10 Finland
Malignant neoplasm: Cerebellum
+∞
7.3
7
*
8000/0-C71.6
ICD-O-3
Neoplasm, benign of cerebellum, NOS
+∞
7.3
7
*
C71.69
ICD-10 Finland
Malignant tumor of the cerebellum other or unspecified histology
+∞
7.3
7
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
+∞
7.3
7
*
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
+∞
7.3
7
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
+∞
7.3
7
*
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
+∞
7.3
7
*
AAF50
NOMESCO Finland
Third ventriculostomy
+∞
7.3
7
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
16.4
7.3
11
7
TAB00
NOMESCO Finland
Lumbar puncture
3.8
7.2
23
66
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
31.1
7.2
9
*
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
31.1
7.2
9
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
23.3
6.7
9
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
6.7
90
539
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
6.6
47
215
Z2445
NOMESCO Finland
Psychologist
3.4
6.5
24
76
R42
ICD-10 Finland
Dizziness and giddiness
2.3
6.5
63
331
9421/1-C71.9
ICD-O-3
Pilocytic astrocytoma of brain, NOS
71.8
6.5
7
*
N18
ICPC
Paralysis/weakness
8.5
6.4
13
16
WF002
NOMESCO Finland
Radical radiotherapy
4.0
6.2
18
48
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
13.0
6.1
10
8
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
10
34.35
23.47
2.1
2.0
—
—
—
0
0
63
208
3.82
16.65
7.7
11.1
0.46
0.86
mmol/l
0.35
50
178
23
25
10.12
11.82
3.2
1.2
—
—
—
0
0
26
57
5.03
11.51
2.2
2.1
19.44
20.40
e6/l
0.02
18
42
26
58
4.94
11.28
2.3
2.2
668.94
239.76
e6/l
0.65
18
46
142
898
2.59
10.57
8.6
7.9
1.20
1.22
mmol/l
1.29
133
835
15
10
15.96
9.66
2.7
1.2
—
—
—
0
0
148
988
2.47
9.30
7.3
8.5
1.21
1.22
mmol/l
1.14
134
868
90
490
2.40
8.90
2.7
2.5
—
—
—
0
0
43
173
2.84
7.83
7.3
11.0
24.05
24.83
mmol/l
0.92
43
173
17
25
7.26
7.45
5.0
3.8
1.69
2.97
nmol/l
0.98
17
25
131
928
1.99
5.90
3.0
2.9
—
—
estimate
—
0
0
10
12
8.66
5.11
2.5
4.7
60.10
221.25
nmol/l
—
10
12
114
850
1.69
3.69
4.8
5.8
36.67
36.14
g/l
0.50
105
813
48
278
1.92
3.66
8.0
8.2
104.77
104.54
mmol/l
0.13
48
278
7
9
7.98
3.58
1.3
1.1
—
—
—
0
0
5
164
0.29
2.68
1.2
1.4
—
—
—
0
0
49
316
1.70
2.60
1.9
1.6
943.24
1222.85
nmol/l
1.27
38
238
33
195
1.81
2.36
5.3
7.1
—
—
—
0
0
6
13
4.71
2.28
1.3
1.1
—
—
—
0
0
93
723
1.49
2.20
3.7
3.4
—
—
—
0
0
72
543
1.48
1.94
2.0
2.3
2.98
2.79
mg/l
0.28
61
479
125
1053
1.42
1.84
6.6
7.3
10.42
12.59
umol/l
1.58
117
1005
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
12
4.23
1.83
1.4
1.2
—
—
—
0
0
91
725
1.43
1.82
3.2
3.8
19.48
35.84
ng/l
1.66
56
488
49
346
1.53
1.79
2.2
5.0
0.82
0.81
mmol/l
0.17
44
329
7
25
2.86
1.66
1.7
1.4
2.34
3.17
ug/l
—
7
20
6
21
2.91
1.51
1.3
1.1
—
—
—
0
0
16
89
1.86
1.41
1.7
1.6
255.62
338.07
mu/l
0.82
16
82
166
1504
1.40
1.40
8.2
8.1
77.82
82.38
u/l
0.84
155
1421
5
18
2.82
1.29
1.4
1.0
—
—
—
0
0
73
593
1.34
1.23
4.0
3.3
0.15
0.33
e6/l
1.07
61
426
33
234
1.48
1.20
4.2
4.6
31.13
32.79
%
0.44
23
147
5
20
2.53
1.15
1.4
1.1
—
—
—
0
0
169
1556
1.35
1.13
4.8
4.4
14.57
14.73
pmol/l
0.34
153
1422
48
370
1.38
1.12
3.8
3.1
0.72
0.92
e6/l
0.30
33
184
17
107
1.64
1.03
2.3
1.6
—
—
—
0
0
41
314
1.37
1.00
2.0
2.0
—
—
—
0
0
83
708
1.27
0.95
4.7
3.4
2.36
2.36
mmol/l
0.06
71
642
43
337
1.34
0.91
4.1
3.2
2.81
2.42
e6/l
0.08
27
153
49
393
1.32
0.89
3.5
2.6
2.41
2.44
mmol/l
1.88
42
347
37
471
0.74
0.88
1.9
2.1
0.70
1.35
mg/l
2.43
30
369
105
929
1.25
0.87
2.8
2.7
76.86
76.27
nmol/l
0.07
97
842
72
612
1.26
0.84
2.3
2.6
52.58
61.19
u/l
0.59
65
577
204
1961
1.45
0.82
19.5
15.4
21.51
22.15
mg/l
0.11
180
1598
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
32
247
1.34
0.76
2.0
1.8
—
—
—
0
0
114
1029
1.22
0.75
3.0
3.1
120.47
96.00
ug/l
0.50
103
968
71
816
0.81
0.74
2.0
1.9
1.39
1.34
mmol/l
0.23
64
693
10
60
1.70
0.73
1.1
1.4
—
—
—
0
0
10
61
1.67
0.69
2.1
2.0
—
—
—
0
0
7
42
1.69
0.69
1.4
1.1
—
—
—
0
0
94
840
1.21
0.67
2.5
2.0
100.04
97.51
pmol/l
0.18
56
408
181
1887
0.79
0.67
5.7
5.5
2.83
2.71
mmol/l
1.21
170
1761
179
1867
0.79
0.65
4.9
4.9
4.75
4.63
mmol/l
0.94
168
1751
19
139
1.40
0.63
3.7
3.0
75.17
67.84
ml/min/173m2
—
6
63
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
178
1854
0.81
0.60
4.9
4.8
1.48
1.48
mmol/l
0.00
168
1729
36
294
1.27
0.59
3.1
3.1
1.02
0.77
ug/l
0.84
23
184
45
379
1.23
0.57
1.6
1.7
444.92
474.92
pmol/l
0.32
36
328
10
65
1.56
0.56
1.9
2.2
—
—
—
0
0
18
236
0.74
0.54
1.6
2.0
3.77
3.38
ratio
0.55
13
182
43
499
0.83
0.48
2.5
2.9
315.42
335.25
umol/l
0.63
36
439
10
68
1.49
0.48
1.0
1.1
—
—
—
0
0
8
57
1.42
0.42
1.0
2.2
—
—
—
0
0
28
233
1.23
0.41
2.0
1.9
—
—
—
0
0
187
1812
1.19
0.41
17.2
14.5
87.52
84.70
ml/min/173m2
0.99
173
1657
52
583
0.86
0.40
3.4
4.1
2.09
8.76
mg/mmol
4.66
34
373
44
385
1.18
0.39
4.3
4.8
22.06
21.70
%
0.07
24
179
5
36
1.40
0.38
1.2
1.3
—
—
—
0
0
5
36
1.40
0.38
1.2
1.3
—
—
—
0
0
156
1496
1.14
0.37
4.3
4.4
11.05
10.94
mm/h
0.03
145
1384
6
42
1.44
0.36
1.3
1.7
—
—
—
0
0
130
1364
0.89
0.35
3.3
3.4
—
—
—
0
0
40
351
1.17
0.35
1.3
1.5
—
—
—
0
0
13
100
1.32
0.34
1.5
1.2
—
—
—
0
0
188
1830
1.17
0.34
6.2
5.3
1.69
1.88
mu/l
1.94
175
1689
19
155
1.25
0.33
3.9
5.1
2.35
1.38
mmol/l
0.59
14
109
15
187
0.79
0.33
1.6
1.8
3.42
3.42
mmol/l
—
10
132
129
1229
1.12
0.32
8.4
10.7
4.16
3.96
e9/l
0.44
107
1067
15
185
0.80
0.31
2.7
2.2
—
—
—
0
0
9
118
0.75
0.28
1.8
1.5
1188.93
892.11
mu/l
—
9
99
172
1766
0.89
0.28
6.2
5.9
36.82
38.71
mmol/mol
2.84
161
1669
10
128
0.77
0.27
1.1
1.0
—
—
—
0
0
8
67
1.20
0.26
1.0
1.1
—
—
—
0
0
77
819
0.91
0.25
4.0
3.7
0.00
0.01
estimate
0.50
12
195
57
615
0.90
0.24
3.2
3.1
0.00
0.00
estimate
-0.00
14
191
5
42
1.19
0.21
1.4
1.4
58.00
55.66
ug/l
—
5
42
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
152.30
—
0
11
0
10
0.00
0.21
0.0
3.4
—
4.64
—
0
10
0
10
0.00
0.21
0.0
3.4
—
10.66
—
0
10
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
3.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
91.14
—
0
7
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
12
0.00
0.21
0.0
1.0
—
120.50
—
0
12
0
12
0.00
0.21
0.0
3.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
104.75
—
0
8
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
44
476
0.91
0.20
1.9
1.7
—
—
—
0
0
6
53
1.14
0.19
1.0
1.1
—
16.77
—
0
10
34
310
1.11
0.19
2.7
2.7
2.32
2.36
g/l
0.15
29
285
5
67
0.74
0.17
3.2
2.9
—
—
—
0
0
51
478
1.09
0.17
3.9
4.0
1.02
1.02
kg/l
0.28
41
306
13
151
0.85
0.16
1.3
1.3
178.40
115.43
u/ml
—
5
59
9
78
1.16
0.15
1.3
1.9
—
—
—
0
0
107
1100
0.95
0.12
4.4
4.0
0.00
0.00
estimate
-0.00
17
226
28
301
0.92
0.11
2.6
2.4
—
—
—
0
0
175
1772
0.94
0.10
4.1
4.2
1.27
1.25
mmol/l
0.19
160
1641
39
370
1.07
0.09
3.5
3.8
37.75
220.40
ng/l
1.47
28
283
6
55
1.09
0.09
1.2
1.5
—
—
—
0
0
16
146
1.10
0.08
1.3
1.5
—
—
—
0
0
5
60
0.83
0.08
1.0
1.7
—
—
—
0
0
5
62
0.80
0.08
1.0
1.6
—
—
—
0
0
184
1822
1.06
0.08
4.9
4.7
5.64
5.84
mmol/l
2.01
173
1684
7
68
1.03
0.08
1.4
1.3
—
—
—
0
0
6
73
0.82
0.07
1.2
1.1
1.48
1.55
g/l
—
6
73
6
74
0.81
0.07
1.2
1.1
0.95
0.89
g/l
—
6
74
7
83
0.84
0.07
1.1
1.3
—
—
—
0
0
7
84
0.83
0.07
1.7
1.6
—
—
—
0
0
169
1672
1.04
0.07
25.4
20.4
332.79
332.41
g/l
0.23
169
1667
37
354
1.05
0.07
1.4
1.3
8.31
7.28
u/ml
0.06
15
145
56
544
1.04
0.06
1.3
1.4
3.63
1.57
u/ml
0.38
13
143
13
119
1.10
0.06
1.0
1.3
—
—
—
0
0
110
1083
1.03
0.05
4.1
3.9
0.00
6.85
estimate
0.50
17
237
18
169
1.07
0.05
2.8
2.7
13.45
13.48
nmol/l
0.00
18
162
203
2041
0.94
0.04
12.4
11.9
25.70
25.52
u/l
0.06
195
1991
59
602
0.97
0.03
3.8
3.9
0.00
0.00
estimate
-0.00
14
216
169
1680
1.02
0.02
21.8
19.6
13.36
13.56
%
1.74
169
1669
15
158
0.95
0.02
2.3
2.1
—
—
—
0
0
17
164
1.04
0.00
1.6
2.5
0.18
0.18
e6/l
0.01
17
156
39
384
1.02
0.00
1.3
1.3
12.35
27.18
iu/ml
2.04
11
127
107
1076
0.99
0.00
4.2
3.9
0.00
0.00
estimate
-0.00
16
235
136
1362
1.00
0.00
3.6
3.5
47.00
43.11
u/l
0.25
127
1298
213
2127
1.03
0.00
29.0
23.5
4.50
4.50
e12/l
0.03
208
2086
32
325
0.98
0.00
2.7
2.5
—
—
—
0
0
213
2126
1.04
0.00
29.1
23.5
261.99
252.67
e9/l
1.32
208
2091
19
185
1.03
0.00
3.2
3.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
5
57
0.87
0.00
1.6
1.5
—
—
—
0
0
6
63
0.95
0.00
1.0
1.4
—
—
—
0
0
7
74
0.94
0.00
1.3
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
2.4
—
141.89
—
0
9
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
13
130
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
68.30
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
25.80
—
0
5
0
5
0.00
-0.00
0.0
10.0
—
6.26
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.8
—
191.13
—
0
8
5
52
0.96
-0.00
1.2
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
53
530
1.00
-0.00
2.2
3.6
508.83
1276.99
ng/l
2.99
43
451
5
54
0.92
-0.00
1.0
1.5
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.3
—
64.33
—
0
9
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.57
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BRAIN_INFRATENT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_INFRATENT | 1.861 [1.47, 2.35] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.201 |
During the follow-up period (1.1.1998 — 31.12.2019), 125 out of 692 females with CD2_BENIGN_BRAIN_INFRATENT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_INFRATENT | 2.417 [1.8, 3.24] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.089 |
During the follow-up period (1.1.1998 — 31.12.2019), 122 out of 603 males with CD2_BENIGN_BRAIN_INFRATENT died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BRAIN_INFRATENT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.215% | 0.496% |
| 5 | 1.161% | 3.052% |
| 10 | 2.919% | 7.476% |
| 15 | 5.319% | 14.591% |
| 20 | 9.131% | 24.239% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRAIN_INFRATENT – Benign neoplasm: Brain, infratentorial
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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