No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
314 |
4. Check minimum number of eventsNone |
314 |
5. Include endpointsNone |
314 |
6. Filter based on genotype QC (FinnGen only) |
271 |
Control definitions (FinnGen only)
- Control exclude
- K11_INTESTOTH
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Impaction of intestines
based on the number of shared cases.
Similar with more cases:
- Paralytic ileus and intestinal obstruction
- Other diseases of intestines
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3077 | 1658 | 1372 |
| Only index persons | 1888 | 1071 | 817 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.04 |
| Only index persons | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 66.50 | 69.86 | 62.39 |
| Only index persons | 59.60 | 63.66 | 54.27 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 271 | 149 | 122 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.06 |
| Median age at first event (years) | 61.74 | 58.51 | 65.69 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 277
- Matched controls
- 2770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K56.4
ICD-10 Finland
Other impaction of intestine
+∞
146.2
127
*
K56.3
ICD-10 Finland
Gallstone ileus
+∞
102.6
92
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
15.4
65.7
63
52
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
774.4
64.6
61
*
JN3AD
NOMESCO Finland
Abdominal CT examination
9.4
60.4
88
131
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
12.9
51.4
54
51
UJF32
NOMESCO Finland
Coloscopy
6.8
50.8
108
238
K56.7
ICD-10 Finland
Ileus, unspecified
+∞
45.0
42
*
K59.09
ICD-10 Finland
Constipation, unspecified
12.5
41.0
43
40
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
5.1
40.6
150
521
K59.0
ICD-10 Finland
Constipation
11.6
37.2
41
41
WX302
NOMESCO Finland
Thoracal epidural anesthesy
12.4
35.4
37
34
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
+∞
34.1
32
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.0
31.9
55
95
JFB00
NOMESCO Finland
Partial resection of small intestine
66.9
26.6
30
5
JFA00
NOMESCO Finland
Enterotomy
+∞
24.3
23
*
56030
ICD-8 Finland
Intestinal obstruction without mention of hernia, Impaction of intestine
+∞
23.2
22
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
91.3
23.1
25
*
JAH00
NOMESCO Finland
Laparotomy
17.9
20.7
32
20
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.4
20.3
105
423
5603C
ICD-9 Finland
Intestinal obstruction without mention of hernia, Impaction of intestine[OBSTRUCTIO INTESTINALIS,KOVETTUNUT SUOLENSISÄLTÖ]
+∞
20.0
19
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
7.8
18.6
27
38
A06AC01
ATC
ispaghula (psylla seeds); oral
3.4
18.3
89
342
K56.0
ICD-10 Finland
Paralytic ileus
+∞
17.9
17
*
A06AD11
ATC
lactulose; oral
3.6
17.0
69
236
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.8
16.5
32
61
ZXD05
NOMESCO Finland
Urgent procedure
2.9
15.9
115
548
UJF30
NOMESCO Finland
Ileoscopy through colon
5.5
15.7
32
64
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
36.1
13.7
17
5
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.7
13.5
22
35
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
13.1
13.4
23
19
N02AX02
ATC
tramadol; systemic, rectal
2.5
13.0
139
788
N03AX16
ATC
[U] pregabalin
2.8
12.0
78
344
UJG02
NOMESCO Finland
Proctoscopy
20.0
11.7
17
9
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
11.0
84
400
N05AH04
ATC
quetiapine; oral
2.8
10.6
62
258
A02BC02
ATC
pantoprazole; systemic
2.5
10.5
197
1386
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
+∞
10.5
10
*
K56.2
ICD-10 Finland
Volvulus
+∞
10.5
10
*
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
24.5
10.3
14
6
N06AX21
ATC
duloxetine; oral
3.3
10.2
41
137
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
10.2
76
357
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
10.1
62
264
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.3
10.0
41
139
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.6
9.8
66
294
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.6
9.6
63
277
5603X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Impaction of intestine[OBSTRUCTIO INTESTINALIS,MUU SUOLEN SISÄINEN SYY]
+∞
9.4
9
*
6421
FHL
Appendicectomy
4.4
9.4
24
58
P01AB01
ATC
metronidazole; oral, rectal
2.2
9.4
114
660
B01AB05
ATC
enoxaparin; parenteral
2.2
8.9
103
582
JFA70
NOMESCO Finland
Suture of small intestine
51.7
8.7
10
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
8.7
35
117
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
8.6
45
175
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
7.1
8.5
20
30
K62.3
ICD-10 Finland
Rectal prolapse
+∞
8.4
8
*
45599
ICD-8 Finland
Haemorrhoids
+∞
8.4
8
*
A07EC02
ATC
mesalazine; oral, rectal
4.6
8.3
20
46
N05BA04
ATC
oxazepam; oral
2.3
8.3
85
455
R15
ICD-10 Finland
Faecal incontinence
10.5
8.1
15
15
JAH01
NOMESCO Finland
Laparoscopy
4.5
8.1
20
47
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
22.8
8.1
11
5
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.7
7.9
26
76
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
7.8
64
310
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
46.3
7.8
9
*
N02AA05
ATC
oxycodone; systemic
2.3
7.7
69
347
SPAT1255
SPAT
Intravenous administration of medicine
3.5
7.6
27
83
J01MA12
ATC
levofloxacin; systemic
2.4
7.5
62
301
N05BA01
ATC
diazepam; systemic, rectal
2.6
7.4
45
189
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
7.3
42
171
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
+∞
7.3
7
*
56096
ICD-8 Finland
Intestinal obstruction without mention of hernia, Ileus propter adhaesionem (functione laesa circulationis intestinalis non indicata)
+∞
7.3
7
*
N05CF01
ATC
zopiclone; oral
2.0
7.2
104
630
R10.0
ICD-10 Finland
Acute abdomen
9.1
7.1
14
16
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.2
7.0
29
98
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.0
7.0
32
115
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
7.0
41
169
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
14.2
6.9
11
8
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
4.5
6.9
17
40
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
7.5
6.8
15
21
K50.8
ICD-10 Finland
Other Crohn disease
17.2
6.8
10
6
C10AC01
ATC
colestyramine; oral
8.1
6.7
14
18
R11
ICD-10 Finland
Nausea and vomiting
2.9
6.7
33
124
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
6.7
98
595
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
5.6
6.6
18
34
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.6
6.6
22
65
R02
ICPC
Shortness of breath/dyspnoea
2.5
6.5
45
201
B80
ICPC
Iron deficiency anaemia
7.7
6.5
14
19
6561
FHL
Removal of fasteners and related measures
71.4
6.5
7
*
JF1AD
NOMESCO Finland
Small bowel CT
71.4
6.5
7
*
P29
ICPC
Psychological sympt/compl other
3.2
6.4
26
87
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
6.2
6.4
16
27
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.8
6.3
19
52
N05AA02
ATC
levomepromazine; systemic
5.3
6.3
18
36
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
+∞
6.3
6
*
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
+∞
6.3
6
*
K59.01
ICD-10 Finland
Constipation outlet obstruction type
+∞
6.3
6
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
6.2
42
186
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
6.2
57
289
R52.2
ICD-10 Finland
Other chronic pain
4.3
6.2
16
39
ZX120
NOMESCO Finland
Intravenous
2.6
6.2
36
148
N06AX16
ATC
venlafaxine; oral
2.5
6.1
41
180
D01
ICPC
Abdominal pain/cramps general
2.7
6.1
33
130
AA1AD
NOMESCO Finland
CT of head and brain
2.0
6.1
91
552
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
6.1
136
942
N06AX11
ATC
mirtazapine; oral
1.9
6.1
100
627
N06AB06
ATC
sertraline; oral
2.6
6.1
36
149
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.1
6.1
17
44
C05AA08
ATC
fluocortolone; rectal, topical
2.6
6.0
36
150
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
131
618
3.12
19.18
4.8
2.2
59.69
63.34
u/l
0.12
126
566
75
303
3.02
13.77
7.8
5.9
104.44
104.25
mmol/l
0.12
75
303
108
567
2.48
11.60
2.9
2.1
3.06
2.95
mg/l
0.14
88
486
152
983
2.21
9.52
4.6
2.6
—
—
estimate
—
0
0
37
123
3.32
9.26
7.1
7.5
24.64
24.95
mmol/l
0.16
37
123
137
866
2.15
8.91
6.1
3.9
31.30
51.51
ng/l
1.33
107
645
43
160
3.00
8.91
2.4
1.4
—
—
—
0
0
54
228
2.70
8.86
5.5
3.6
6.04
5.75
kpa
1.29
54
218
90
495
2.21
8.21
4.5
2.2
—
—
—
0
0
150
1003
2.08
8.19
4.5
2.9
103.34
118.57
ug/l
0.74
138
919
47
193
2.73
8.11
4.0
2.2
37.70
30.02
u/l
0.55
40
164
127
802
2.08
8.06
5.1
3.1
—
—
—
0
0
146
973
2.06
7.98
8.9
4.4
34.35
35.27
g/l
1.08
139
905
171
1208
2.09
7.96
15.5
9.3
4.34
4.16
e9/l
0.54
156
1058
163
1141
2.04
7.66
11.2
6.7
1.20
1.21
mmol/l
1.00
152
972
33
115
3.12
7.63
1.8
1.3
—
—
—
0
0
71
365
2.27
7.55
3.6
2.5
11.24
13.03
umol/l
1.46
66
338
212
1645
2.23
7.45
14.2
7.5
83.36
80.35
u/l
0.29
207
1539
180
1325
2.02
7.13
9.0
4.5
6.55
6.76
mmol/l
0.83
174
1263
50
228
2.46
6.94
12.4
7.2
116.16
121.32
g/l
1.01
50
221
36
141
2.79
6.77
9.8
8.5
91.05
93.82
%
0.59
36
141
50
233
2.40
6.61
3.2
2.4
10.42
8.29
umol/l
0.30
45
209
47
213
2.45
6.60
4.7
3.7
3.97
47.36
ug/l
0.75
39
179
72
392
2.13
6.57
2.3
1.8
—
—
—
0
0
68
366
2.14
6.37
5.3
2.9
0.82
0.82
mmol/l
0.08
61
343
74
412
2.09
6.35
2.1
1.6
1224.87
1180.80
nmol/l
0.12
58
314
161
1169
1.90
6.31
6.8
4.0
0.00
0.00
estimate
-0.00
42
247
45
204
2.44
6.31
3.4
1.9
0.18
0.21
g/l
1.81
40
184
81
468
2.03
6.28
2.4
1.7
0.77
1.44
mg/l
2.69
62
379
56
282
2.24
6.18
11.6
6.4
11.39
11.69
kpa
0.21
56
270
31
118
2.83
6.14
3.1
4.2
1.93
1.80
mmol/l
0.05
26
83
44
202
2.40
5.99
5.0
2.8
4.42
4.39
kpa
0.03
44
192
161
1183
1.86
5.94
6.9
3.9
0.00
1.33
estimate
0.51
40
232
157
1158
1.82
5.59
6.9
3.9
0.00
0.00
estimate
-0.00
40
240
106
698
1.84
5.45
2.3
1.7
22.12
21.51
nmol/l
0.14
86
577
56
297
2.11
5.39
1.9
1.8
—
—
—
0
0
78
468
1.93
5.33
2.0
1.7
430.65
436.05
pmol/l
0.07
69
389
112
756
1.81
5.27
4.2
3.2
2.33
2.36
mmol/l
2.77
99
681
110
739
1.81
5.26
3.4
3.3
2125.13
1455.42
ng/l
0.75
100
650
98
638
1.83
5.18
6.6
4.1
0.00
0.00
estimate
-0.00
40
217
19
60
3.33
5.14
2.5
2.0
137.47
125.64
g/l
0.95
19
47
176
1368
1.79
5.02
5.6
3.0
41.63
47.25
u/l
0.62
168
1287
138
1002
1.75
4.99
3.0
2.1
91.30
94.56
pmol/l
0.35
84
510
16
46
3.63
4.97
2.1
1.2
—
—
—
0
0
62
356
1.96
4.78
4.3
2.9
3.91
1.74
e6/l
1.11
34
182
140
1031
1.72
4.73
11.1
5.9
1.20
1.21
mmol/l
2.01
132
935
31
136
2.44
4.65
12.9
7.0
14.95
16.05
%
1.08
31
128
30
130
2.47
4.62
2.2
1.7
—
—
—
0
0
103
703
1.74
4.53
4.2
2.8
26.22
30.45
u/l
0.99
92
670
71
439
1.83
4.34
1.4
1.2
0.87
1.96
u/ml
0.85
19
111
51
286
1.96
4.18
2.0
1.8
—
—
—
0
0
62
372
1.86
4.15
4.3
2.8
0.99
0.84
e6/l
0.23
34
198
26
115
2.39
3.85
11.9
4.2
1.62
1.53
%
0.11
26
105
10
20
5.14
3.72
3.0
1.4
—
—
—
0
0
10
20
5.14
3.72
3.0
1.4
—
—
—
0
0
10
20
5.14
3.72
3.0
1.4
—
—
—
0
0
78
521
1.69
3.59
4.6
4.1
1.02
1.02
kg/l
0.61
48
351
14
46
3.15
3.58
1.4
1.2
215.33
292.77
ug/g
—
9
26
17
63
2.81
3.56
2.9
1.7
—
—
—
0
0
190
1585
1.63
3.49
6.2
4.2
13.01
13.31
mm/h
0.11
180
1451
9
18
5.13
3.40
2.4
1.4
—
—
—
0
0
118
885
1.58
3.38
7.2
4.0
0.09
0.02
estimate
0.35
33
202
36
193
1.99
3.35
2.2
2.5
0.59
0.69
e6/l
0.07
36
186
17
66
2.68
3.28
2.2
2.8
—
—
—
0
0
9
19
4.86
3.26
2.4
1.4
—
—
—
0
0
9
19
4.86
3.26
2.4
1.4
—
—
—
0
0
80
551
1.64
3.24
3.8
2.8
358.71
348.18
umol/l
0.41
72
484
55
343
1.75
3.21
2.3
1.7
30.23
29.20
s
0.65
55
333
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
16
61
2.72
3.19
3.4
2.4
0.30
0.35
iu/ml
—
10
29
26
126
2.17
3.14
7.8
3.3
43.09
48.29
%
0.48
26
120
18
74
2.53
3.12
2.8
1.8
—
—
—
0
0
69
462
1.66
3.11
3.7
3.0
2.44
2.46
mmol/l
0.89
64
419
8
16
5.11
3.07
7.5
2.1
—
—
—
0
0
6
8
7.63
3.07
1.0
1.0
—
—
—
0
0
88
629
1.58
3.04
5.9
3.0
0.39
0.44
e6/l
0.14
72
472
16
64
2.59
2.93
1.8
1.2
—
—
—
0
0
89
645
1.56
2.87
7.4
3.5
0.03
0.13
estimate
0.38
36
194
192
1644
1.55
2.81
5.3
4.3
14.93
14.96
pmol/l
0.06
173
1506
149
1216
1.49
2.70
3.5
2.9
—
—
—
0
0
11
35
3.23
2.67
4.5
4.8
5.02
5.18
kpa
0.25
11
35
14
56
2.58
2.57
2.9
1.6
—
—
—
0
0
124
984
1.47
2.54
4.0
2.3
77.52
76.95
nmol/l
0.08
112
862
6
12
5.08
2.41
1.8
1.5
—
—
—
0
0
5
8
6.34
2.38
2.4
1.0
—
—
—
0
0
9
28
3.29
2.33
1.2
1.4
—
—
—
0
0
9
30
3.07
2.16
7.0
5.6
—
380.80
—
0
5
9
30
3.07
2.16
1.6
1.2
—
—
—
0
0
5
10
5.07
2.08
2.0
1.7
—
—
—
0
0
12
50
2.46
2.05
1.8
1.9
—
—
—
0
0
9
32
2.87
2.02
1.6
1.4
—
—
—
0
0
65
473
1.49
2.00
5.2
4.0
1403.67
271.44
ng/l
0.64
53
385
230
2105
1.55
1.99
38.3
15.4
29.78
24.85
mg/l
1.23
214
1730
12
51
2.41
1.98
1.6
1.6
—
—
—
0
0
32
197
1.71
1.97
2.3
1.6
1.51
1.51
%
0.01
27
168
35
221
1.67
1.97
5.1
3.4
—
—
—
0
0
9
33
2.78
1.95
2.6
3.6
6.47
9.66
pmol/l
—
9
33
28
168
1.74
1.89
5.4
4.0
120.25
93.47
ng/l
0.50
21
145
21
116
1.88
1.84
1.2
3.3
4.05
4.48
pmol/l
0.77
14
97
94
752
1.38
1.71
4.8
4.2
4.19
10.05
mg/mmol
2.21
58
471
6
19
3.20
1.67
2.0
2.2
1.22
0.54
mmol/l
—
6
19
7
25
2.85
1.66
1.7
1.3
—
—
—
0
0
7
25
2.85
1.66
1.1
1.0
—
—
—
0
0
29
185
1.63
1.59
2.7
2.5
12.85
7.63
ug/l
0.25
23
164
216
1980
1.41
1.59
6.9
5.2
1.96
1.96
mu/l
0.03
198
1802
52
380
1.45
1.57
1.4
1.3
86.54
36.35
iu/ml
—
9
116
7
28
2.54
1.46
1.1
1.1
—
—
—
0
0
12
59
2.08
1.46
1.5
1.4
—
—
—
0
0
5
16
3.16
1.44
1.0
1.1
—
—
—
0
0
9
39
2.35
1.44
1.2
1.3
10.66
31.02
u/l
—
9
33
7
29
2.45
1.40
2.1
1.7
9.29
11.00
mmol/l
—
7
29
5
17
2.98
1.36
1.0
1.4
—
—
—
0
0
9
42
2.18
1.35
1.9
1.5
—
—
—
0
0
11
54
2.08
1.34
2.9
2.5
752.33
102.04
ug/min
—
6
29
5
18
2.81
1.29
6.2
3.4
—
—
—
0
0
6
25
2.43
1.25
1.0
1.1
—
177.06
—
0
7
11
56
2.00
1.24
1.3
1.2
—
—
—
0
0
9
169
0.52
1.23
1.9
2.1
3.57
3.32
ratio
—
9
128
12
64
1.91
1.20
1.4
1.4
—
—
—
0
0
5
20
2.53
1.15
1.0
1.1
—
—
—
0
0
25
168
1.54
1.14
2.6
3.1
68.14
60.13
ml/min/173m2
0.32
14
62
10
51
2.00
1.12
1.5
1.4
—
—
—
0
0
45
345
1.36
1.06
1.5
1.5
—
—
—
0
0
25
172
1.50
1.04
2.2
1.4
—
—
—
0
0
35
258
1.41
1.03
5.9
5.0
32.57
32.17
%
0.07
23
165
215
2019
1.29
0.98
33.5
15.0
77.47
77.82
ml/min/173m2
0.07
206
1863
214
2010
1.28
0.97
7.9
6.6
39.46
39.73
mmol/mol
0.16
195
1874
44
342
1.34
0.95
1.4
1.3
24.36
10.31
u/ml
0.40
21
113
7
37
1.91
0.94
1.0
1.5
—
—
—
0
0
7
130
0.53
0.90
1.6
1.8
3.94
3.41
mmol/l
—
7
90
8
43
1.89
0.88
2.3
1.4
—
—
—
0
0
6
30
2.02
0.87
1.0
1.1
—
—
—
0
0
22
154
1.47
0.86
18.3
6.2
25.20
24.36
mmol/l
0.42
22
145
15
96
1.59
0.86
1.3
1.3
—
—
—
0
0
8
45
1.80
0.85
1.8
1.3
—
—
—
0
0
6
31
1.96
0.85
1.3
1.3
—
—
—
0
0
189
1766
1.22
0.80
40.7
19.5
13.88
13.75
%
0.61
189
1744
10
59
1.72
0.77
1.5
1.4
—
—
—
0
0
33
255
1.33
0.76
7.8
7.5
—
—
—
0
0
9
54
1.69
0.75
1.0
1.3
—
—
—
0
0
9
59
1.54
0.69
1.4
1.2
—
—
—
0
0
7
44
1.61
0.65
1.0
1.4
—
—
—
0
0
7
44
1.61
0.65
1.0
1.4
—
—
—
0
0
215
2052
1.21
0.65
5.8
5.1
5.98
6.00
mmol/l
0.08
195
1875
8
49
1.65
0.62
1.0
1.4
—
—
—
0
0
8
51
1.59
0.61
2.9
1.3
427.00
78.61
e6/l
—
8
41
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
2.4
—
13.30
—
0
22
8
54
1.50
0.58
1.9
1.4
—
—
—
0
0
204
1947
1.18
0.57
5.3
4.3
1.33
1.27
mmol/l
0.64
189
1779
9
60
1.52
0.55
1.4
1.2
—
—
—
0
0
10
67
1.51
0.50
3.2
2.4
1.57
1.61
mg/l
—
10
58
7
47
1.50
0.48
2.9
1.6
—
—
—
0
0
7
51
1.38
0.44
1.1
1.3
—
26.19
—
0
8
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
235
2292
1.17
0.37
53.7
23.4
91.43
91.35
fl
0.08
235
2264
235
2293
1.16
0.36
54.4
23.6
130.03
134.08
g/l
3.60
235
2264
235
2293
1.16
0.36
54.7
23.8
38.86
40.09
%
2.47
235
2263
7
54
1.30
0.30
1.3
1.4
—
—
—
0
0
44
398
1.13
0.26
3.0
3.0
0.73
0.92
ug/l
0.79
32
240
58
537
1.10
0.23
3.9
4.3
19.04
22.89
%
1.06
28
242
216
2117
1.09
0.21
6.6
5.7
2.56
2.67
mmol/l
1.12
201
1955
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
8.93
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
9.20
—
0
10
19
214
0.88
0.16
2.2
2.2
—
—
—
0
0
28
300
0.93
0.10
1.7
1.4
—
—
—
0
0
6
73
0.82
0.07
2.8
1.9
—
—
—
0
0
18
193
0.93
0.06
2.1
2.0
—
—
—
0
0
68
662
1.04
0.06
5.6
5.0
1.97
3.53
ug/l
1.42
61
592
10
91
1.10
0.04
1.0
1.0
—
—
—
0
0
10
109
0.91
0.04
1.1
2.0
—
—
—
0
0
87
883
0.98
0.03
2.5
1.8
1.45
1.33
mmol/l
0.71
68
742
206
2059
1.00
0.00
6.1
4.9
1.44
1.47
mmol/l
0.37
191
1896
207
2073
0.99
0.00
6.1
5.0
4.45
4.58
mmol/l
0.96
194
1924
12
125
0.96
0.00
2.1
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
0.27
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
0.23
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
15.71
—
0
8
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
1.37
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_IMPACT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_IMPACT | 1.676 [1.35, 2.08] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.109 |
During the follow-up period (1.1.1998 — 31.12.2019), 288 out of 744 females with K11_IMPACT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_IMPACT | 2.113 [1.56, 2.85] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 212 out of 515 males with K11_IMPACT died.
Mortality risk
Mortality risk for people of age
years, who have K11_IMPACT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.154% | 0.352% |
| 5 | 0.97% | 2.227% |
| 10 | 2.367% | 5.192% |
| 15 | 4.398% | 10.302% |
| 20 | 7.868% | 16.948% |
Relationships between endpoints
↥Index endpoint: K11_IMPACT – Impaction of intestines
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data