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Right ventricular outflow tract obstruction

Endpoint Browser PheWeb

Q17_RVOTO

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q220|Q221|Q222|Q223|Q2240|Q2241|Q226|Q228|Q229|Q243|Q255|Q256
  • Hospital discharge: ICD-9 — 7460B|7460C|7460X|7461B|7461A|7468X|7468B|7473A
  • Hospital discharge: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Hospital discharge: excluded ICD-9 — 758|7595|75683
  • Cause of death: ICD-10 — Q220|Q221|Q222|Q223|Q2240|Q2241|Q226|Q228|Q229|Q243|Q255|Q256
  • Cause of death: ICD-9 — 7460B|7460C|7460X|7461B|7461A|7468X|7468B|7473A
  • Cause of death: excluded ICD-10 — Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Cause of death: excluded ICD-9 — 758|7595|75683

2 out of 7 registries used, show all original rules.

316

4. Check minimum number of events

None

316

5. Include endpoints

None

316

6. Filter based on genotype QC (FinnGen only)

274

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4198 2225 1962
Only index persons 2655 1420 1235
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.05
Only index persons 0.05 0.05 0.05
Median age at first event (years)
Whole population 0.66 0.59 0.58
Only index persons 3.15 3.48 2.76

-FinnGen-

Key figures

All Female Male
Number of individuals 274 148 126
Unadjusted period prevalence (%) 0.05 0.05 0.06
Median age at first event (years) 6.11 8.87 2.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
305
Matched controls
3050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
201.0
170
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
38.1
176.5
120
51
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
27.2
162.3
129
80
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
19.7
154.2
159
160
201
Kela drug reimbursment
Chronic cardiac insufficiency
45.5
152.4
95
30
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
43.5
132.8
83
26
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
14.3
126.8
199
353
XF404
NOMESCO Finland
Ambulatory ECG
18.5
113.8
105
84
XF400
NOMESCO Finland
ECG with 12 standard connections
11.7
106.7
168
290
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
62.0
106.0
60
12
C03DA01
ATC
spironolactone; oral
17.4
105.7
100
83
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
37.5
98.0
63
21
XF402
NOMESCO Finland
ECG with work load test
18.9
97.8
86
62
B01AA03
ATC
warfarin; systemic
16.8
95.1
90
74
C01AA05
ATC
digoxin; systemic
44.5
95.0
58
16
C03CA01
ATC
furosemide; systemic
12.2
94.3
119
152
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.3
82.0
105
135
TPH07
NOMESCO Finland
Cathetrisation of artery
10.0
75.8
108
158
FM2CE, ,
NOMESCO Finland
12.6
74.9
84
89
ZXE20
NOMESCO Finland
More than three and less than five hours
9.1
70.6
110
178
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.7
64.9
123
245
Q21.10
ICD-10 Finland
Persistent ostium secundum
20.2
63.2
51
30
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
21.4
62.5
49
27
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.6
58.2
202
700
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
22.6
56.5
43
22
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
54.9
51
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
10.4
54.5
68
82
ZXD10
NOMESCO Finland
Scheduled procedure
5.9
52.0
192
685
Z2221
NOMESCO Finland
Medical doctor
5.6
49.8
167
545
61
HP
Catheterization and pressure measurement of the left side of the heart
290.6
49.6
49
*
31
HP
Congenital heart failure surgery
152.4
49.5
51
*
ZXE10
NOMESCO Finland
More than one and less than three hours
5.5
48.9
173
588
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
22.0
48.3
37
19
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
8.4
47.7
71
106
WX408
NOMESCO Finland
General anesthesy, balanced
5.3
47.2
162
534
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
43.8
41
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
249.2
43.1
43
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
9.0
41.8
57
76
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
61.4
40.9
47
9
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
7.5
40.5
66
108
XF600
NOMESCO Finland
Bloodpressure measurement
6.2
40.2
83
173
62
HP
Catheterization and pressure measurement of the right side of the heart
441.4
40.1
39
*
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
65.6
39.5
45
8
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
39.4
37
*
R4110
NOMESCO Finland
Physiotherapy
4.4
35.9
148
540
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
389.7
35.7
35
*
TFP20
NOMESCO Finland
Cardiodefibrillation
14.0
35.5
34
27
WX872
NOMESCO Finland
Intensive care
15.4
35.3
32
23
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.4
34.6
128
429
Q20.48
ICD-10 Finland
Single ventricle
196.9
34.5
35
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
34.0
32
*
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
190.6
33.4
34
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
11.2
33.4
37
37
WX882
NOMESCO Finland
High dependency care
5.9
32.7
69
145
Z98.8
ICD-10 Finland
Other specified postsurgical states
67.7
31.8
36
6
XF622
NOMESCO Finland
Measurement of minute volume of heart
78.6
31.6
35
5
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
52.4
31.4
37
8
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
+∞
30.7
29
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
56.2
30.1
35
7
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
45.0
29.7
36
9
ZXD05
NOMESCO Finland
Urgent procedure
3.9
29.5
133
504
Q21.30
ICD-10 Finland
Tetralogy of Fallot
89.2
29.4
32
*
207
Kela drug reimbursment
Chronic arrhythmias
7.7
29.3
44
65
WX892
NOMESCO Finland
Monitored bed care
5.9
28.8
59
120
I48
ICD-10 Finland
Atrial fibrillation and flutter
7.5
28.5
44
67
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
27.5
26
*
Z3231
NOMESCO Finland
Registered nurse
3.5
25.4
154
693
ZXE00
NOMESCO Finland
One hour or less
3.5
25.3
172
830
TPH04
NOMESCO Finland
Cathetrisation of vein
3.9
24.7
93
306
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
24.3
23
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.6
23.9
32
41
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
+∞
23.2
22
*
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
43.9
23.1
28
7
Q22.2
ICD-10 Finland
Congenital pulmonary valve insufficiency
+∞
22.1
21
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
123.9
21.9
23
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
123.9
21.9
23
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
19.7
21.4
32
18
C01BD01
ATC
amiodarone; systemic
30.6
21.4
28
10
G04BE03
ATC
sildenafil; oral
40.4
21.1
26
7
WX704
NOMESCO Finland
Intubation
5.5
20.4
43
89
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
20.0
19
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
7.5
19.4
29
42
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.6
19.1
78
267
ZX120
NOMESCO Finland
Intravenous
4.5
19.0
52
134
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
18.9
18
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
41.2
18.8
23
6
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
17.7
18.7
29
18
Z3226
NOMESCO Finland
Physiotherapist
3.1
18.4
102
421
Q87.14
ICD-10 Finland
Noonan's syndrome
101.0
17.8
19
*
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
101.0
17.8
19
*
WX402
NOMESCO Finland
General anaesthesia
2.9
17.7
118
538
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
190.6
17.7
18
*
C07AA07
ATC
sotalol; systemic
23.5
17.1
24
11
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
67.3
16.9
19
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
16.8
16
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
95.4
16.7
18
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
13.2
16.7
29
24
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
19.9
16.3
24
13
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
50.4
16.2
19
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
63.5
15.9
18
*
C09AA02
ATC
enalapril; systemic
4.6
15.6
40
97
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
168.3
15.6
16
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
168.3
15.6
16
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
14.1
15.5
26
20
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
47.6
15.2
18
*
I50.9
ICD-10 Finland
Heart failure, unspecified
6.2
15.2
27
47
602
Kela drug reimbursment
Children's severe malnutrition
5.5
14.9
30
59
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
14.7
14
*
74734
ICD-8 Finland
Other congenital anomalies of circulatory system, Stenosis, hypoplasia sive aplasia arteriae pulmonalis
+∞
14.7
14
*
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
157.2
14.6
15
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
157.2
14.6
15
*
C07AB07
ATC
bisoprolol; oral
2.8
14.5
96
429
I44.2
ICD-10 Finland
Atrioventricular block, complete
18.7
14.0
21
12
7AX01, ,
NOMESCO Finland
31.7
14.0
18
6
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
78.8
13.7
15
*
RS224, ,
NOMESCO Finland
13.7
13.6
23
18
Q22.40
ICD-10 Finland
Congenital tricuspid stenosis
+∞
13.6
13
*
1EA01, ,
NOMESCO Finland
146.2
13.6
14
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.2
13.5
60
214
Q21.19
ICD-10 Finland
Atrial septal defect NOS
42.1
13.3
16
*
ZX199
NOMESCO Finland
Other rote
17.7
13.2
20
12
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
52.4
13.0
15
*
I47.1
ICD-10 Finland
Supraventricular tachycardia
5.3
12.9
27
55
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.5
12.7
119
625
WX002
NOMESCO Finland
Sedation and analgesia
3.2
12.6
56
199
5253
FHL
Cardiac lung machine
+∞
12.6
12
*
7468X
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[MUU SYDÄMEN EPÄMUODOSTUMA]
+∞
12.6
12
*
Q22.3
ICD-10 Finland
Other congenital malformations of pulmonary valve
+∞
12.6
12
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
12.6
86
388
FM1BD
NOMESCO Finland
Extensive CT of heart
135.3
12.5
13
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.6
12.3
31
74
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
6.0
12.1
22
39
B01AB05
ATC
enoxaparin; parenteral
2.9
12.1
65
258
R07.4
ICD-10 Finland
Chest pain, unspecified
2.7
12.0
77
335
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.3
12.0
49
165
EBA15
NOMESCO Finland
Extraction of multiple teeth
5.7
12.0
23
43
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.6
11.9
43
134
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
17.3
11.8
18
11
XQ903
NOMESCO Finland
Production of other scan or drawing
31.4
11.8
15
5
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
31.4
11.8
15
5
Q21.0
ICD-10 Finland
Ventricular septal defect
31.4
11.8
15
5
RD210, ,
NOMESCO Finland
4.2
11.7
33
86
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
67.6
11.7
13
*
Q21.3
ICD-10 Finland
Tetralogy of Fallot
+∞
11.5
11
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
124.5
11.5
12
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
36.5
11.4
14
*
Z2446
NOMESCO Finland
Social worker
2.9
11.2
62
249
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
4.0
11.2
33
89
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.5
11.1
28
67
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
11.0
73
322
Z94.1
ICD-10 Finland
Heart transplant status
22.4
10.8
15
7
Q24.0
ICD-10 Finland
Dextrocardia
113.8
10.5
11
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
113.8
10.5
11
*
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
113.8
10.5
11
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
10.5
10
*
Q22.6
ICD-10 Finland
Hypoplastic right heart syndrome
+∞
10.5
10
*
7461A
ICD-9 Finland
Other congenital anomalies of heart, Tricuspid atresia and stenosis, congenital[VITIUM VALVULAE TRICUSPIDALIS CONGENITUM CUM ATRESI]
+∞
10.5
10
*
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
33.8
10.4
13
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
9.6
10.2
20
22
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
9.9
79
379
Q26.1
ICD-10 Finland
Persistent left superior vena cava
56.8
9.7
11
*
ZX108
NOMESCO Finland
Inhalation
15.7
9.6
15
10
I49.5
ICD-10 Finland
Sick sinus syndrome
15.7
9.6
15
10
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.5
9.6
24
57
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
31.1
9.5
12
*
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
103.1
9.5
10
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
103.1
9.5
10
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
103.1
9.5
10
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
22.5
9.4
13
6
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
9.4
9
*
AEX
HP
Other pulmonary or pulmonary artery valve procedure
+∞
9.4
9
*
7460B
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITUM CUM ATRESIA]
+∞
9.4
9
*
ZXA00
NOMESCO Finland
Right side
2.6
9.4
62
272
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
37.9
9.1
11
*
127
Kela drug reimbursment
Transplant complication
5.1
9.0
19
39
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.9
8.9
44
165
I50.0
ICD-10 Finland
Congestive heart failure
10.5
8.6
16
16
L04AA06
ATC
mycophenolic acid; systemic
5.1
8.5
18
37
205
Kela drug reimbursment
Chronic hypertension
3.2
8.5
36
124
Q25.1
ICD-10 Finland
Coarctation of aorta
11.2
8.4
15
14
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
+∞
8.4
8
*
7452A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Tetralogy of Fallot[TETRALOGIA FALLOT]
+∞
8.4
8
*
Q25.5
ICD-10 Finland
Atresia of pulmonary artery
+∞
8.4
8
*
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
8.4
8
*
FK1AC
NOMESCO Finland
Right cardioangiography
+∞
8.4
8
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
8.4
8
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
8.4
8
*
F83
ICD-10 Finland
Mixed specific developmental disorders
3.8
8.3
26
73
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.3
8.2
32
104
B34.9
ICD-10 Finland
Viral infection, unspecified
3.3
8.2
32
104
I50.1
ICD-10 Finland
Left ventricular failure
12.2
8.2
14
12
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.3
8.1
21
51
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
34.3
8.1
10
*
3A077, ,
NOMESCO Finland
34.3
8.1
10
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
8.1
8.0
17
22
UGC02
NOMESCO Finland
Rigid bronchoscopy
11.2
7.9
14
13
R62.0
ICD-10 Finland
Delayed milestone
3.4
7.8
29
92
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
46.2
7.8
9
*
XF620
NOMESCO Finland
Examination of circulation with color method
46.2
7.8
9
*
FJD96
NOMESCO Finland
Other operation on right ventricle outlet for congenital or acquired obstruction
46.2
7.8
9
*
R00.0
ICD-10 Finland
Tachycardia, unspecified
4.3
7.7
20
49
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.3
7.6
68
340
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
10.4
7.6
14
14
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.1
7.6
21
54
L04AD02
ATC
tacrolimus; systemic
6.3
7.5
19
32
I48.4
ICD-10 Finland
Atypical atrial flutter
82.0
7.4
8
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
82.0
7.4
8
*
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
82.0
7.4
8
*
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
13.8
7.4
12
9
5504
FHL
Subclavian pulmonary anastomosis (Blalock)
+∞
7.3
7
*
Q22.8
ICD-10 Finland
Other congenital malformations of tricuspid valve
+∞
7.3
7
*
FBE20
NOMESCO Finland
Reconstruction of pulmonary artery using tube graft
+∞
7.3
7
*
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
+∞
7.3
7
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
7.3
7
*
FBJ00
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery
+∞
7.3
7
*
FM1CD
NOMESCO Finland
Very extensive CT of heart
+∞
7.3
7
*
FBE00
NOMESCO Finland
Expansion of pulmonary artery
+∞
7.3
7
*
7453B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Common ventricle[COMMON VENTRICLE]
+∞
7.3
7
*
5233
FHL
Right ventricular bypass surgery (Fontan et al.)
+∞
7.3
7
*
AP3
HP
Catheterization of the right and left side of the heart
+∞
7.3
7
*
5239
FHL
Other measure in this category
+∞
7.3
7
*
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
+∞
7.3
7
*
AP2
HP
Catheterization of the right side of the heart
+∞
7.3
7
*
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
+∞
7.3
7
*
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
16.2
7.3
11
7
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
4.2
7.2
19
47
Q21.21
ICD-10 Finland
Atrioventricular duct
30.8
7.2
9
*
324, ,
NOMESCO Finland
30.8
7.2
9
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.4
7.0
25
77
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.9
7.0
33
121
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
14.2
6.9
11
8
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
8.6
6.9
14
17
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.6
6.9
14
17
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
11.3
6.9
12
11
I47.2
ICD-10 Finland
Ventricular tachycardia
9.6
6.9
13
14
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
7.5
6.8
15
21
TFJ02
NOMESCO Finland
Muscle biopsy of heart
17.2
6.8
10
6
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
17.2
6.8
10
6
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
41.0
6.8
8
*
C09AA05
ATC
ramipril; oral
2.8
6.7
34
129
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.8
6.7
34
129
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
6.7
92
541
J96.1
ICD-10 Finland
Chronic respiratory failure
23.1
6.7
9
*
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.5
6.7
23
69
R50.9
ICD-10 Finland
Fever, unspecified
2.1
6.7
80
448
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
6.7
42
179
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
6.5
66
347
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.7
6.5
37
150
Q22.5
ICD-10 Finland
Ebstein anomaly
71.3
6.4
7
*
FBE96
NOMESCO Finland
Other expansion or reconstruction of pulmonary artery
71.3
6.4
7
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
71.3
6.4
7
*
1CX08, ,
NOMESCO Finland
71.3
6.4
7
*
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
71.3
6.4
7
*
FFK20
NOMESCO Finland
Atrio-pulmonary anastomosis
71.3
6.4
7
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
71.3
6.4
7
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.9
6.4
30
109
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
3.8
6.4
20
56
I35.0
ICD-10 Finland
Aortic (valve) stenosis
8.4
6.4
13
16
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
9.6
6.3
12
13
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
6.3
27
93
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
18.5
6.3
9
5
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
+∞
6.3
6
*
7473A
ICD-9 Finland
Other congenital anomalies of circulatory system, Anomalies of pulmonary artery
+∞
6.3
6
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
+∞
6.3
6
*
7468B
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[STENOSIS PULMONALIS INFUNDIBULARIS]
+∞
6.3
6
*
74654
ICD-8 Finland
Congenital anomalies of heart, Maleformatio valvulae tricuspidalis (morbus Ebstein incluso)
+∞
6.3
6
*
WZC30
NOMESCO Finland
Teaching
2.4
6.2
45
205
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
6.2
23
73
RK260, ,
NOMESCO Finland
12.9
6.1
10
8
K80
ICPC
Cardiac arrhythmia NOS
3.2
6.1
25
84
K84
ICPC
Heart disease other
8.9
6.1
12
14
C10AA03
ATC
pravastatin; oral
5.8
6.1
16
29
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
6.3
6.1
15
25

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
133
102
22.35
150.01
7.6
4.8
180.03
200.43
ng/l
0.14
127
91
212
357
17.20
143.46
10.8
5.2
712.33
868.09
ng/l
0.51
206
289
131
361
5.61
47.30
8.1
3.2
2693.09
1136.06
ng/l
0.88
115
204
189
713
5.34
46.45
21.3
8.4
1.43
1.13
inr
9.79
162
597
161
555
5.03
43.71
4.1
3.3
—
—
—
0
0
163
641
4.31
35.56
12.0
7.6
70.64
89.03
%
16.45
163
634
171
703
4.26
34.89
4.3
3.2
—
—
—
0
0
95
268
4.70
31.87
21.8
13.0
105.88
104.84
mmol/l
1.41
95
268
74
173
5.33
31.09
30.0
16.0
0.07
0.34
mmol/l
0.26
69
148
74
174
5.29
30.87
30.1
15.9
7.42
7.40
ph
0.43
12
77
128
466
4.01
30.20
4.6
4.3
1.64
1.78
mg/l
0.10
99
342
61
130
5.62
28.29
34.1
15.5
1.11
1.25
%
0.91
61
130
60
128
5.59
27.77
34.9
15.6
0.60
0.70
%
1.88
60
128
192
1022
3.37
23.44
4.8
3.3
—
—
estimate
—
0
0
88
292
3.83
22.97
2.8
2.1
—
—
—
0
0
111
439
3.40
22.01
25.3
12.5
—
—
—
0
0
112
489
3.04
18.27
26.6
16.1
25.05
24.87
mmol/l
0.31
112
489
109
475
3.01
17.77
6.5
4.2
—
—
—
0
0
181
1043
2.81
17.24
12.9
8.0
18.87
20.41
umol/l
0.31
175
989
131
688
2.58
14.33
3.6
3.5
2.96
2.45
mg/l
0.90
121
606
69
259
3.15
14.28
2.0
1.5
—
—
—
0
0
42
121
3.87
13.04
6.4
15.1
0.69
0.58
%
1.32
42
121
184
1201
2.34
11.67
25.0
12.1
1.20
1.22
mmol/l
4.14
173
1083
172
1094
2.31
11.56
10.3
10.7
—
—
—
0
0
108
563
2.42
11.53
5.1
2.9
30.43
18.26
ng/l
0.67
71
282
81
375
2.58
11.11
16.8
9.2
—
—
—
0
0
19
16
12.58
10.99
2.7
7.1
4.95
4.78
kpa
0.38
19
16
16
10
16.79
10.46
2.4
2.3
99.13
96.10
g/l
—
16
10
95
486
2.39
10.43
9.4
11.3
7.37
7.37
ph
0.28
69
324
94
480
2.39
10.35
9.4
11.2
1.26
1.02
mmol/l
0.41
83
398
203
1428
2.26
10.14
10.9
10.2
0.55
0.67
%
2.51
195
1368
203
1429
2.26
10.11
10.9
10.1
3.02
3.11
%
0.20
195
1369
203
1436
2.24
9.89
10.9
10.2
9.30
8.42
%
5.34
195
1378
86
435
2.36
9.59
17.6
9.4
7.42
7.41
ph
1.82
80
342
86
439
2.34
9.37
17.7
9.3
5.13
5.06
kpa
0.43
86
425
143
899
2.11
9.25
7.8
8.5
—
—
—
0
0
205
1485
2.16
9.00
11.0
10.0
27.01
33.41
%
13.02
199
1440
201
1451
2.13
8.82
10.9
9.9
57.92
51.75
%
10.71
196
1414
207
1515
2.14
8.71
11.2
9.9
0.61
0.55
e9/l
1.41
186
1275
207
1517
2.13
8.65
11.2
9.9
0.04
0.04
e9/l
0.75
186
1274
285
2414
3.75
8.51
38.4
14.5
139.30
139.58
mmol/l
1.58
285
2360
26
73
3.80
8.32
6.5
19.6
70.18
69.87
%
0.03
26
73
23
59
4.13
8.31
5.3
23.2
12.03
11.84
%
0.08
23
59
209
1554
2.10
8.18
11.2
9.9
1.71
2.24
e9/l
12.31
190
1350
25
71
3.75
7.87
2.2
2.2
—
—
—
0
0
25
71
3.75
7.87
2.2
2.2
—
—
—
0
0
25
71
3.75
7.87
2.2
2.2
—
—
—
0
0
25
71
3.75
7.87
2.2
2.2
—
—
—
0
0
209
1566
2.06
7.85
11.9
10.6
0.19
0.20
e9/l
0.55
188
1343
50
218
2.55
7.59
1.5
1.2
—
—
—
0
0
66
333
2.25
7.23
2.2
1.8
—
—
—
0
0
213
1637
2.00
7.06
12.5
12.5
3.77
3.70
e9/l
0.18
190
1379
210
1617
1.96
6.78
12.4
7.1
99.33
99.90
u/l
0.04
204
1535
187
1392
1.89
6.63
4.9
3.8
85.16
68.83
ug/l
0.91
180
1341
15
27
5.78
5.76
4.6
2.5
—
—
—
0
0
20
62
3.38
5.55
2.0
2.4
5.80
10.40
index
0.38
15
38
186
1427
1.78
5.52
14.7
12.5
0.00
0.00
e9/l
0.47
161
1110
33
140
2.52
5.28
2.7
2.1
119.43
108.73
au/ml
0.22
14
59
16
35
4.77
5.25
2.3
2.2
—
—
—
0
0
291
2626
3.36
5.19
22.1
9.7
—
—
—
0
0
38
174
2.35
5.17
4.5
5.9
0.31
0.54
%
0.49
13
57
137
980
1.72
5.07
4.9
5.2
11.03
49.60
e6/l
1.56
96
621
18
56
3.35
4.98
1.2
1.2
3.70
3.57
u/ml
—
10
28
40
192
2.25
4.88
4.9
6.2
0.53
0.67
%
0.19
16
68
15
42
3.70
4.83
1.3
1.2
—
—
—
0
0
38
180
2.27
4.78
4.9
6.5
0.00
0.15
%
1.71
14
55
125
887
1.69
4.67
1.8
1.6
—
—
—
0
0
47
246
2.08
4.62
4.3
5.5
70.27
67.38
e9/l
0.14
34
158
76
474
1.80
4.45
3.5
3.3
560.77
570.95
mosm/kgh2o
0.14
68
409
115
811
1.67
4.33
4.3
4.4
19.47
39.14
e6/l
0.99
93
591
10
17
6.04
4.16
1.2
1.7
17.20
10.42
umol/l
—
10
17
31
143
2.30
4.15
2.8
2.1
—
—
—
0
0
80
519
1.73
4.07
4.2
3.4
4.82
7.44
e6/l
0.83
73
462
16
54
3.07
3.91
1.3
1.2
—
—
—
0
0
36
182
2.11
3.88
5.2
6.7
0.00
0.04
%
0.80
11
50
12
28
4.42
3.86
1.0
1.2
—
—
—
0
0
12
28
4.42
3.86
1.0
1.0
—
—
—
0
0
11
24
4.71
3.78
8.3
3.0
7.21
6.41
mmol/l
0.27
11
24
17
63
2.80
3.55
2.1
4.1
15.18
9.87
%
0.97
17
63
17
63
2.80
3.55
2.2
4.1
50.47
66.86
%
1.84
17
63
72
470
1.70
3.54
2.7
4.0
3.49
1.95
e6/l
0.49
41
239
12
31
3.99
3.53
1.8
1.5
1.42
0.87
index
0.94
12
31
8
13
6.29
3.52
3.3
2.5
4.09
3.85
mmol/l
—
8
13
8
13
6.29
3.52
3.3
2.5
107.50
105.85
mmol/l
—
8
13
8
13
6.29
3.52
3.3
2.5
1.21
1.20
mmol/l
—
8
13
102
737
1.58
3.33
4.3
4.3
0.33
0.27
e6/l
0.19
83
518
12
33
3.74
3.33
7.8
2.9
1.30
1.24
mmol/l
0.12
12
33
13
45
2.97
3.06
5.0
4.1
4.28
3.19
e9/l
0.78
13
45
21
94
2.33
3.04
2.2
2.5
—
—
—
0
0
48
292
1.76
3.02
5.5
3.4
9.08
9.44
g/l
0.19
48
282
281
2594
2.06
2.99
28.4
12.8
26.03
22.14
mg/l
1.25
248
1936
15
58
2.67
2.92
1.1
3.3
—
—
—
0
0
28
144
2.04
2.91
3.0
3.1
0.18
0.14
e6/l
0.16
28
137
8
20
4.08
2.58
2.3
1.2
—
—
—
0
0
79
568
1.53
2.56
7.3
3.8
7.39
7.39
ph
0.22
63
399
6
12
5.08
2.41
1.0
1.2
36.67
28.00
s
—
6
12
5
8
6.33
2.38
2.2
3.4
17.00
29.63
%
—
5
8
5
8
6.33
2.38
2.0
3.4
23.40
8.00
%
—
5
8
11
39
2.89
2.37
7.5
6.1
7.45
5.63
pmol/l
0.49
11
39
8
23
3.54
2.28
2.3
1.5
30.50
32.74
pg
—
8
23
79
582
1.48
2.26
2.9
2.5
—
—
—
0
0
5
9
5.63
2.22
1.0
1.2
—
—
—
0
0
31
182
1.78
2.22
2.1
1.9
—
—
—
0
0
12
48
2.56
2.21
5.3
4.3
7.41
7.40
ph
0.17
12
48
0
55
0.00
2.09
0.0
1.9
—
3.71
—
0
55
9
31
2.96
2.09
3.6
2.6
—
—
—
0
0
10
37
2.76
2.09
3.0
1.4
13218.00
6013.27
e6/l
—
10
26
5
10
5.06
2.08
1.4
1.1
5.80
6.54
mmol/l
—
5
10
19
342
0.53
2.01
1.7
1.9
—
—
—
0
0
13
57
2.34
2.00
2.0
4.1
15.31
25.42
%
2.67
13
57
7
21
3.39
1.97
1.3
1.0
—
—
—
0
0
8
27
3.01
1.95
2.8
1.1
—
—
—
0
0
6
16
3.80
1.94
1.5
1.8
4.25
6.19
ug/l
—
6
16
16
79
2.08
1.89
1.2
1.2
—
—
—
0
0
28
168
1.73
1.88
3.0
2.0
175.37
165.03
u/ml
0.09
19
78
9
34
2.70
1.88
1.1
1.2
—
—
—
0
0
79
603
1.42
1.86
7.7
5.5
—
—
—
0
0
19
101
1.94
1.85
1.5
2.0
77.51
20.21
ng/l
0.64
19
101
20
345
0.55
1.84
1.8
1.9
—
—
—
0
0
5
12
4.22
1.83
2.2
3.2
366.00
133.75
e6/l
—
5
12
20
343
0.55
1.81
1.8
1.9
—
—
—
0
0
20
342
0.56
1.79
1.8
1.9
—
—
—
0
0
19
324
0.56
1.69
1.7
1.9
—
—
—
0
0
10
40
2.55
1.68
1.2
2.4
—
—
—
0
0
13
63
2.11
1.62
2.2
4.4
34.77
15.57
%
1.77
13
63
7
26
2.73
1.59
1.0
2.0
—
—
—
0
0
5
15
3.37
1.53
1.0
1.2
—
—
—
0
0
14
72
1.99
1.51
1.5
1.4
232.67
325.23
ug/g
—
6
39
9
37
2.48
1.49
5.3
6.1
—
—
—
0
0
202
1823
1.32
1.49
4.8
4.5
35.80
37.13
mmol/mol
1.58
193
1743
9
38
2.41
1.47
5.4
4.5
7.92
9.38
kpa
—
9
38
9
38
2.41
1.47
5.4
4.5
4.68
4.97
kpa
—
9
38
6
22
2.76
1.44
5.3
3.7
—
—
—
0
0
5
120
0.41
1.40
2.4
1.6
—
—
—
0
0
218
1998
1.32
1.38
5.5
4.0
15.51
14.56
pmol/l
6.07
205
1863
17
97
1.80
1.38
1.4
1.4
—
—
—
0
0
84
1020
0.76
1.37
1.6
1.8
0.68
2.73
u/ml
2.99
24
204
12
61
2.01
1.34
3.0
3.7
13.82
25.85
u/ml
0.31
12
61
12
218
0.53
1.34
1.2
1.2
10.23
6.23
u/ml
—
7
170
17
277
0.59
1.30
1.8
2.0
—
—
—
0
0
34
237
1.49
1.29
2.1
2.5
31.21
32.54
u/l
0.08
28
195
12
62
1.97
1.29
8.5
11.7
—
—
—
0
0
12
215
0.54
1.29
1.0
1.2
3.17
1.34
u/ml
—
7
154
204
1863
1.29
1.27
4.2
3.4
1.16
1.21
mmol/l
0.75
194
1759
9
45
2.03
1.24
1.6
1.1
—
—
—
0
0
18
285
0.61
1.24
1.2
1.3
—
—
—
0
0
60
750
0.75
1.19
1.8
1.9
—
—
—
0
0
16
95
1.72
1.16
4.3
2.7
59.38
52.77
%
0.94
16
95
5
20
2.52
1.15
1.2
1.1
—
—
—
0
0
5
20
2.52
1.15
4.2
1.8
1004.00
788.15
u/ml
—
5
20
14
80
1.79
1.15
1.5
1.5
—
—
—
0
0
217
2011
1.27
1.12
4.6
3.9
4.19
4.53
mmol/l
4.86
210
1912
38
280
1.41
1.11
1.6
1.6
—
—
—
0
0
25
171
1.50
1.06
1.6
1.8
0.00
0.00
estimate
—
5
51
15
238
0.61
1.06
1.1
1.3
28.95
2.78
u/ml
—
10
174
9
46
1.99
1.04
1.8
2.7
0.40
0.88
e9/l
—
9
46
13
75
1.77
1.04
8.3
6.3
37.02
36.96
°c
0.63
13
75
9
47
1.94
1.03
6.8
5.5
—
—
—
0
0
14
84
1.70
0.99
1.9
1.6
—
—
—
0
0
22
149
1.51
0.98
1.0
1.1
—
—
—
0
0
0
29
0.00
0.98
0.0
1.6
—
—
—
0
0
0
29
0.00
0.98
0.0
15.9
—
790.90
—
0
29
21
143
1.50
0.92
1.0
1.2
—
—
—
0
0
6
29
2.09
0.90
2.5
1.2
460.92
378.82
mu/l
—
6
24
51
409
1.30
0.89
6.7
4.5
358.20
323.24
umol/l
1.24
51
384
88
755
1.23
0.88
2.1
1.8
—
—
—
0
0
35
266
1.36
0.87
1.4
1.3
—
—
—
0
0
22
154
1.46
0.86
3.5
1.7
—
—
—
0
0
73
619
1.24
0.81
4.7
3.5
0.00
0.00
estimate
0.50
28
230
0
25
0.00
0.79
0.0
2.3
—
2.89
—
0
20
0
25
0.00
0.79
0.0
10.4
—
0.59
—
0
25
240
2286
1.23
0.77
6.3
4.7
2.15
1.87
mu/l
2.42
230
2167
56
464
1.25
0.76
1.7
1.7
—
—
—
0
0
17
242
0.68
0.76
2.0
2.4
—
—
—
0
0
10
159
0.62
0.74
2.2
2.3
—
—
—
0
0
213
2009
1.20
0.74
4.9
4.1
2.56
2.72
mmol/l
1.88
204
1904
49
590
0.80
0.72
5.1
3.0
1.02
1.02
kg/l
0.06
33
364
211
1994
1.19
0.69
4.6
3.9
1.33
1.41
mmol/l
2.26
202
1889
11
69
1.62
0.69
2.6
4.0
29.29
36.83
%
0.73
11
69
20
268
0.73
0.65
3.2
2.3
9.84
12.56
nmol/l
0.79
20
249
55
464
1.23
0.65
1.6
1.5
21.54
20.27
nmol/l
0.20
48
407
11
165
0.65
0.65
1.1
1.1
—
—
—
0
0
8
49
1.65
0.62
1.6
1.8
—
—
—
0
0
17
232
0.72
0.62
4.5
2.2
9.27
13.24
iu/l
0.47
17
168
5
30
1.68
0.61
1.8
3.0
—
—
—
0
0
73
830
0.84
0.61
2.9
2.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
224.08
—
0
21
44
366
1.24
0.60
1.4
1.5
391.11
380.38
titre
—
9
53
0
22
0.00
0.59
0.0
3.0
—
46.18
—
0
22
0
22
0.00
0.59
0.0
1.3
—
18.75
—
0
8
0
22
0.00
0.59
0.0
5.9
—
7.82
—
0
22
0
22
0.00
0.59
0.0
1.3
—
23.67
—
0
6
8
55
1.47
0.56
1.9
1.3
403.38
317.30
mu/l
—
8
44
48
561
0.83
0.55
2.6
3.6
101.15
100.25
ug/g
0.01
41
454
6
38
1.59
0.54
2.5
5.8
5.98
6.50
mmol/l
—
6
32
6
38
1.59
0.54
5.3
3.3
16.63
30.73
mg/l
—
6
28
7
45
1.57
0.49
1.0
1.0
162.14
162.80
g/l
—
7
45
136
1266
1.13
0.49
4.5
3.6
0.00
6.33
estimate
0.50
30
238
13
175
0.73
0.46
1.5
1.2
—
18.04
—
0
7
135
1260
1.13
0.46
4.4
3.6
0.00
0.00
estimate
-0.00
30
243
136
1272
1.12
0.44
4.4
3.6
0.00
0.00
estimate
-0.00
28
230
49
557
0.86
0.42
1.8
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
37.33
—
0
15
0
15
0.00
0.41
0.0
2.2
—
28.60
—
0
15
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
7.0
—
—
—
0
0
203
1949
1.12
0.41
3.8
3.4
5.51
5.56
mmol/l
0.25
194
1805
31
366
0.83
0.41
1.3
1.3
24.96
7.37
u/ml
0.32
11
130
38
440
0.84
0.40
1.3
1.3
—
—
—
0
0
7
103
0.67
0.40
1.3
1.2
—
—
—
0
0
7
104
0.67
0.40
1.0
1.0
2.89
3.29
kpa
—
7
90
7
105
0.66
0.40
1.0
1.0
7.41
7.18
kpa
—
7
91
7
105
0.66
0.40
1.0
1.0
21.14
19.42
mmol/l
—
7
105
7
105
0.66
0.40
1.0
1.0
—
—
—
0
0
66
730
0.88
0.39
1.7
1.8
87.99
97.14
pmol/l
1.06
39
367
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
18
144
1.27
0.36
1.1
1.4
151.85
240.73
miu/ml
—
6
74
10
133
0.74
0.34
1.8
1.2
—
—
—
0
0
6
46
1.31
0.33
1.2
5.3
—
—
—
0
0
7
96
0.72
0.31
1.0
1.4
—
—
—
0
0
7
56
1.26
0.29
1.9
8.4
43.56
83.40
mg/mmol
—
7
50
83
890
0.91
0.29
4.9
3.1
0.00
0.01
estimate
0.50
25
208
23
195
1.19
0.29
4.8
3.3
—
—
—
0
0
91
851
1.10
0.29
2.0
2.0
1.17
1.36
mmol/l
1.76
85
756
10
129
0.77
0.28
1.0
1.1
—
—
—
0
0
5
72
0.69
0.26
1.6
1.2
—
—
—
0
0
5
42
1.19
0.21
2.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
7.5
—
6.70
—
0
11
0
11
0.00
0.21
0.0
1.7
—
135.36
—
0
11
0
11
0.00
0.21
0.0
1.4
—
0.00
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
46
424
1.10
0.20
4.3
3.7
66.98
93.28
mg/l
0.34
32
306
10
122
0.81
0.19
1.0
1.0
7.99
8.69
mu/l
—
10
107
14
164
0.85
0.19
1.6
1.8
6.17
6.23
ph
—
9
103
104
1082
0.94
0.17
4.4
3.2
6.28
6.24
ph
0.12
53
534
27
244
1.12
0.17
1.4
1.3
250.14
130.73
u/ml
—
10
77
33
302
1.10
0.17
2.8
1.8
—
—
—
0
0
12
101
1.20
0.17
1.2
1.8
—
12.52
—
0
5
159
1631
0.95
0.16
5.3
4.2
51.45
35.17
u/l
2.23
154
1585
64
674
0.94
0.15
4.0
2.8
0.00
0.02
estimate
0.68
25
201
26
237
1.11
0.14
1.6
2.5
18272.43
5600.96
u/l
—
7
87
115
1119
1.04
0.11
4.6
3.6
73.56
70.12
nmol/l
0.69
109
1055
82
849
0.95
0.11
2.2
2.3
—
—
—
0
0
44
417
1.06
0.11
5.3
4.4
15.29
11.61
mg/mmol
0.18
31
291
69
665
1.05
0.10
1.9
1.8
—
—
—
0
0
22
203
1.09
0.10
1.1
1.5
—
—
—
0
0
10
87
1.15
0.09
1.0
1.2
—
—
—
0
0
5
47
1.06
0.09
4.4
6.3
3.44
2.17
ug/l
—
5
47
5
48
1.04
0.09
1.0
1.0
—
—
—
0
0
15
164
0.91
0.08
2.1
2.5
0.36
0.85
ug/l
—
6
84
93
953
0.97
0.08
2.0
1.7
1.88
1.80
g/l
0.22
69
531
8
76
1.05
0.07
1.0
1.2
—
3.28
—
0
10
8
76
1.05
0.07
1.1
1.2
—
—
—
0
0
8
90
0.89
0.07
1.9
1.8
1.57
0.56
nmol/l
—
8
79
9
105
0.85
0.06
1.6
1.5
—
—
—
0
0
31
297
1.05
0.05
2.0
2.1
2.41
2.42
mmol/l
0.33
26
263
28
290
0.96
0.03
1.5
1.4
—
—
—
0
0
14
148
0.94
0.02
1.5
1.2
—
—
—
0
0
12
113
1.06
0.02
1.0
1.1
1.32
1.50
g/l
1.71
12
113
10
106
0.94
0.01
1.5
1.6
—
—
—
0
0
22
222
0.99
0.00
1.5
2.0
—
—
—
0
0
12
119
1.01
0.00
1.2
1.2
—
—
—
0
0
12
119
1.01
0.00
1.2
1.2
—
—
—
0
0
12
115
1.05
0.00
1.0
1.1
0.78
0.90
g/l
1.17
12
115
40
395
1.01
0.00
1.4
1.3
16.44
29.59
iu/ml
—
9
96
0
8
0.00
0.00
0.0
1.4
—
63.25
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
8.0
—
109.43
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
71.95
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
15.0
—
18.22
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
5
51
0.98
-0.00
2.2
1.5
6.20
13.35
u/l
—
5
42
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
17.16
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.4
—
43.60
—
0
5
5
50
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
399.20
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
12.05
—
0
6
0
5
0.00
-0.00
0.0
3.4
—
6.48
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_RVOTO and mortality.

Females

Parameter HR [95% CI] p-value
Q17_RVOTO 3.515 [2.39, 5.18] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 1741 females with Q17_RVOTO died.

Males

Parameter HR [95% CI] p-value
Q17_RVOTO 3.988 [2.8, 5.67] < 0.001
Birth year 0.991 [0.98, 1.0] 0.067

During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 1456 males with Q17_RVOTO died.

Mortality risk

Mortality risk for people of age

years, who have Q17_RVOTO.

N-year risk Females Males
1 0.277% 1.065%
5 1.604% 5.562%
10 3.891% 12.841%
15 7.539% 22.479%
20 12.735% 35.979%

Relationships between endpoints

↥

Index endpoint: Q17_RVOTO – Right ventricular outflow tract obstruction

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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