otitis externa: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
514 |
4. Check minimum number of eventsNone |
514 |
5. Include endpointsNone |
514 |
6. Filter based on genotype QC (FinnGen only) |
470 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H60
- Name in latin
- Cellulitis auris externae
Similar endpoints
↥List of similar endpoints to
Cellulitis of external ear
based on the number of shared cases.
Similar with more cases:
- Otitis externa
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3830 | 1988 | 1820 |
| Only index persons | 3515 | 1861 | 1654 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.05 |
| Only index persons | 0.07 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 41.89 | 39.86 | 44.16 |
| Only index persons | 44.32 | 42.14 | 46.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 470 | 282 | 188 |
| Unadjusted period prevalence (%) | 0.09 | 0.10 | 0.09 |
| Median age at first event (years) | 52.51 | 48.83 | 58.03 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 487
- Matched controls
- 4870
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H60.1
ICD-10 Finland
Cellulitis of external ear
+∞
307.7
487
19
H60.9
ICD-10 Finland
Otitis externa, unspecified
16.4
172.1
172
157
H60.3
ICD-10 Finland
Other infective otitis externa
32.9
130.8
87
32
H60.8
ICD-10 Finland
Other otitis externa
18.6
90.9
76
48
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
170.6
58.3
60
*
H01
ICPC
Ear pain/earache
4.6
45.8
135
373
H60
ICD-10 Finland
Otitis externa
6.7
45.0
78
134
H70
ICPC
Otitis externa
14.0
42.2
40
31
A46
ICD-10 Finland
Erysipelas
4.2
37.7
124
368
H66.0
ICD-10 Finland
Acute suppurative otitis media
4.7
35.8
96
243
H29
ICPC
Ear symptom/complaint other
3.9
30.9
107
326
H04
ICPC
Ear discharge
8.0
29.3
41
55
UDC00
NOMESCO Finland
Ear microscopy
4.7
28.6
72
172
H66.9
ICD-10 Finland
Otitis media, unspecified
4.1
25.8
78
214
J01DB01
ATC
cefalexin; oral
5.0
22.1
452
3517
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.8
19.8
126
544
H60.0
ICD-10 Finland
Abscess of external ear
48.1
19.4
23
5
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.0
18.5
98
382
H92.0
ICD-10 Finland
Otalgia
3.9
18.1
58
165
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
7.3
16.7
25
36
Z71.8
ICD-10 Finland
Other specified counselling
2.2
16.2
217
1293
J01FF01
ATC
clindamycin; systemic
2.3
15.4
161
863
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.4
15.3
135
672
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.6
14.9
97
419
H61.8
ICD-10 Finland
Other specified disorders of external ear
37.3
14.5
18
5
H61.2
ICD-10 Finland
Impacted cerumen
3.9
14.5
45
125
D07AC01
ATC
betamethasone; topical
2.1
14.3
205
1241
J01MA02
ATC
ciprofloxacin; systemic
2.1
14.3
200
1200
S02CA02
ATC
flumetasone and antiinfectives; otic
3.9
13.3
41
113
H13
ICPC
Plugged feeling ear
2.4
13.0
111
541
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
20.7
12.5
18
9
H65.3
ICD-10 Finland
Chronic mucoid otitis media
5.0
12.5
27
56
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
12.5
167
975
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.7
11.6
27
60
S76
ICPC
Skin infection other
3.4
11.4
42
131
DC1AD
NOMESCO Finland
Temporalbone CT
16.0
10.9
17
11
DFF00
NOMESCO Finland
Pure tone audiometry
2.7
10.8
60
237
H81
ICPC
Excessive ear wax
2.3
9.9
87
427
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.0
9.8
28
73
H65.2
ICD-10 Finland
Chronic serous otitis media
10.3
9.6
18
18
D05AX52
ATC
calcipotriol, combinations; topical
3.4
9.4
35
110
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
9.3
227
1585
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.7
9.2
30
86
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
9.0
196
1318
D05AX02
ATC
calcipotriol; topical
3.9
8.9
26
69
ZYC01
NOMESCO Finland
Remote contact by phone
2.8
8.7
45
171
H62.0
ICD-10 Finland
Otitis externa in bacterial diseases classified elsewhere
50.9
8.7
10
*
D07CC01
ATC
betamethasone and antibiotics; topical
2.2
8.5
73
354
S18
ICPC
Laceration/cut
1.7
8.3
235
1695
WZC00, ,
SPAT
2.1
8.1
85
446
D07AD01
ATC
clobetasol; topical
2.1
7.9
88
471
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
4.5
7.7
19
44
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.6
7.7
18
40
D07AB08
ATC
desonide; topical
2.3
7.6
63
300
D07XC01
ATC
betamethasone; topical
2.2
7.5
64
308
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.1
7.5
75
386
D07AC13
ATC
mometasone; topical
1.8
7.5
140
891
L03.2
ICD-10 Finland
Cellulitis of face
9.6
7.3
14
15
H65.0
ICD-10 Finland
Acute serous otitis media
6.4
7.3
18
29
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.1
7.1
71
365
M79.6
ICD-10 Finland
Pain in limb
1.7
7.0
218
1590
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
7.0
58
277
L03
ICPC
Low back symptom/complaint
1.7
6.8
150
997
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.6
6.8
22
63
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
40.6
6.8
8
*
H70.0
ICD-10 Finland
Acute mastoiditis
40.6
6.8
8
*
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
17.0
6.8
10
6
R5120
NOMESCO Finland
Preparation of an aid
4.1
6.7
18
45
D02AE01
ATC
carbamide; topical
2.7
6.6
35
135
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
7.0
6.6
15
22
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
6.5
66
340
R07.0
ICD-10 Finland
Pain in throat
2.4
6.5
44
192
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
6.4
267
2082
R42
ICD-10 Finland
Dizziness and giddiness
1.8
6.4
108
664
L17
ICPC
Foot/toe symptom/complaint
1.7
6.3
157
1074
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
6.3
214
1585
J01DA01
ATC
[U] cefalexin
1.6
6.3
290
2314
H61.0
ICD-10 Finland
Perichondritis of external ear
+∞
6.3
6
*
L03.9
ICD-10 Finland
Cellulitis, unspecified
5.5
6.2
17
32
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
6.4
6.2
15
24
ZY010
NOMESCO Finland
Hospital outpatient
2.6
6.2
35
140
S01
ICPC
Pain/tenderness of skin
2.9
6.2
29
105
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.3
6.2
45
203
Z00.0
ICD-10 Finland
General medical examination
1.8
6.0
103
634
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
321
2452
1.91
10.11
5.4
5.1
6.53
6.57
mmol/l
0.11
306
2295
246
1821
1.71
7.73
12.1
12.3
1.15
1.19
inr
0.57
214
1516
374
3215
1.70
5.74
8.8
8.3
74.37
77.26
u/l
0.80
359
3054
205
1537
1.58
5.54
2.8
3.6
28.95
31.81
u/l
1.00
193
1461
334
2803
1.61
5.50
5.4
4.4
450.17
588.97
e6/l
—
6
39
368
3168
1.66
5.42
5.0
4.3
11.24
10.49
mm/h
0.52
348
2979
303
2499
1.56
5.26
12.2
10.0
4.29
4.03
e9/l
1.54
257
2194
191
1429
1.55
5.11
3.5
3.5
7.85
7.93
mmol/l
0.08
165
1235
42
203
2.17
4.91
1.6
1.4
—
—
—
0
0
182
1359
1.54
4.86
3.9
3.2
58.38
94.79
e6/l
0.28
142
1015
457
4233
2.29
4.84
19.2
14.3
22.54
22.73
mg/l
0.04
411
3434
160
1162
1.56
4.83
3.6
3.1
0.14
0.45
e6/l
3.33
120
831
102
664
1.68
4.82
2.1
2.0
—
—
—
0
0
131
916
1.59
4.64
2.9
2.7
6.13
6.62
e6/l
0.15
120
833
272
2228
1.50
4.60
6.0
6.9
10.72
11.37
umol/l
0.21
257
2127
26
105
2.56
4.54
1.5
1.6
—
—
—
0
0
229
1828
1.48
4.30
7.0
6.7
1.20
1.21
mmol/l
1.22
207
1694
169
1286
1.48
3.96
4.1
4.2
12.26
10.71
mg/mmol
0.10
106
810
430
3949
1.76
3.95
5.4
5.4
1.80
1.86
mu/l
0.44
394
3700
247
2030
1.44
3.84
2.5
2.8
—
—
estimate
—
0
0
246
2025
1.43
3.76
7.8
7.5
1.20
1.21
mmol/l
1.11
212
1760
172
1330
1.45
3.66
2.6
2.8
51.92
62.31
u/l
1.35
159
1241
95
657
1.55
3.46
3.1
2.4
2.45
2.35
g/l
0.84
89
608
49
286
1.79
3.40
1.9
1.6
—
—
—
0
0
433
4021
1.69
3.34
17.9
13.4
88.34
86.41
ml/min/173m2
1.05
403
3692
101
722
1.50
3.15
3.4
2.9
1.08
0.78
e6/l
0.64
58
373
70
461
1.61
3.13
2.1
1.9
—
—
—
0
0
105
761
1.48
3.06
3.8
3.7
963.97
364.46
ng/l
0.41
70
536
78
532
1.56
3.01
7.1
7.4
104.40
104.39
mmol/l
0.00
78
532
72
490
1.55
2.81
2.1
1.8
—
—
—
0
0
31
541
0.54
2.79
1.6
1.9
3.79
3.42
ratio
0.96
21
424
210
1744
1.36
2.78
5.1
5.2
35.40
36.27
g/l
1.41
197
1652
57
369
1.62
2.75
7.4
9.7
123.63
119.90
g/l
0.74
57
360
335
2997
1.38
2.71
3.5
3.4
—
—
—
0
0
153
1216
1.38
2.65
2.1
2.2
244.73
251.91
u/l
0.02
146
1160
13
50
2.64
2.55
1.1
1.3
—
—
—
0
0
464
4443
1.94
2.54
13.5
11.6
27.15
26.69
u/l
0.20
448
4344
38
226
1.74
2.52
1.8
1.5
—
—
—
0
0
26
137
1.95
2.51
2.1
1.7
—
—
—
0
0
62
419
1.55
2.50
7.4
9.3
1.22
0.84
mmol/l
0.46
47
350
186
1539
1.34
2.45
3.9
3.5
26.61
69.40
ng/l
0.54
123
1015
56
373
1.57
2.41
3.9
4.1
1.88
1.66
mmol/l
0.17
49
317
60
407
1.54
2.39
2.4
2.5
26.96
31.90
u/l
1.21
54
339
90
666
1.43
2.34
3.5
3.0
3.25
2.56
e6/l
0.27
45
317
30
172
1.79
2.26
2.7
5.1
1.99
1.60
%
0.87
30
159
8
25
3.24
2.10
1.6
1.6
63.13
73.16
umol/l
—
8
25
70
505
1.45
2.09
2.4
3.0
4.91
7.25
umol/l
1.41
55
434
24
413
0.56
2.09
1.5
1.7
3.45
3.39
mmol/l
0.06
14
300
15
71
2.15
1.94
1.3
1.4
—
—
—
0
0
7
22
3.21
1.88
1.9
1.0
—
—
—
0
0
39
254
1.58
1.88
4.0
3.6
1.47
1.41
mmol/l
0.03
29
190
34
214
1.63
1.88
7.6
11.1
16.26
15.62
%
0.70
34
204
36
230
1.61
1.88
7.0
7.0
24.03
24.53
mmol/l
0.31
36
219
90
693
1.37
1.86
3.6
4.0
0.81
0.82
mmol/l
0.20
85
664
263
2347
1.26
1.78
4.6
3.6
0.02
0.00
estimate
0.49
63
495
25
147
1.74
1.77
2.4
1.9
—
—
—
0
0
409
3864
1.37
1.75
6.3
5.9
40.03
38.68
mmol/mol
1.88
382
3661
218
1907
1.26
1.74
2.6
2.5
75.66
74.95
nmol/l
0.14
200
1750
127
1041
1.30
1.71
2.0
1.7
—
—
—
0
0
207
1805
1.26
1.69
1.9
1.9
1.48
1.36
mmol/l
1.12
175
1539
260
2329
1.25
1.66
4.6
3.6
0.00
0.00
estimate
-0.00
61
490
264
2372
1.25
1.63
4.6
3.6
0.00
0.66
estimate
0.51
59
462
361
3366
1.28
1.60
4.3
4.5
14.70
14.69
pmol/l
0.04
327
3093
45
322
1.44
1.44
2.4
2.4
14.43
14.08
au/ml
—
6
32
19
111
1.74
1.41
1.2
1.3
—
—
—
0
0
10
46
2.20
1.40
2.1
1.3
—
—
—
0
0
78
615
1.32
1.40
2.4
1.8
1.55
1.49
%
0.35
71
542
124
1045
1.25
1.32
2.2
2.3
—
—
—
0
0
474
4639
1.82
1.32
28.9
22.1
259.10
252.64
e9/l
1.46
467
4569
199
1765
1.22
1.31
2.0
2.0
92.12
95.80
pmol/l
0.49
88
948
474
4642
1.79
1.27
28.8
22.0
4.54
4.53
e12/l
0.07
468
4563
8
36
2.24
1.24
1.5
1.3
—
—
—
0
0
13
71
1.85
1.20
1.2
1.8
—
—
—
0
0
17
102
1.69
1.17
2.3
2.8
1.38
1.65
index
—
8
60
10
50
2.02
1.17
1.1
1.1
—
—
—
0
0
0
35
0.00
1.15
0.0
1.3
—
8.95
—
0
29
93
772
1.25
1.13
2.7
2.3
—
—
—
0
0
8
40
2.02
1.12
1.1
1.2
—
—
—
0
0
128
1104
1.22
1.10
2.5
2.2
2.72
2.82
mg/l
0.19
111
959
30
213
1.44
1.04
2.4
2.5
0.60
0.62
%
0.13
30
213
17
106
1.63
1.04
1.2
1.2
—
—
—
0
0
36
265
1.39
1.03
1.6
1.5
22.83
22.60
iu/l
0.01
29
226
150
1322
1.19
1.02
3.5
3.0
0.00
0.07
estimate
0.61
48
400
196
1770
1.18
1.01
4.0
3.5
0.00
0.02
estimate
1.34
51
419
33
242
1.39
0.97
2.3
3.0
137.48
129.68
g/l
1.02
33
236
114
984
1.21
0.97
1.8
1.8
0.86
1.23
mg/l
1.71
82
759
9
50
1.81
0.97
1.1
1.1
—
—
—
0
0
13
77
1.71
0.96
1.0
1.1
—
—
—
0
0
0
32
0.00
0.95
0.0
2.6
—
202.22
—
0
27
6
27
2.24
0.93
1.0
1.0
—
—
—
0
0
35
262
1.36
0.92
2.5
2.3
1650.00
4509.12
u/l
—
9
106
6
28
2.16
0.92
1.0
1.1
—
—
—
0
0
15
229
0.64
0.89
5.3
2.4
26.22
32.36
u/ml
0.25
15
221
8
42
1.92
0.89
3.8
4.2
—
—
—
0
0
8
43
1.87
0.87
1.1
1.1
—
—
—
0
0
24
170
1.43
0.87
1.7
1.7
—
—
—
0
0
84
712
1.22
0.86
2.7
2.1
—
—
—
0
0
32
240
1.36
0.85
1.6
1.6
0.18
0.32
mg/l
1.29
20
108
6
32
1.89
0.82
1.0
1.8
—
—
—
0
0
13
81
1.62
0.82
1.2
1.2
—
—
—
0
0
71
596
1.22
0.81
1.7
1.7
926.46
1211.20
nmol/l
2.13
45
459
46
368
1.28
0.79
4.4
5.0
2.91
35.86
ug/l
0.90
41
306
129
1147
1.17
0.79
1.7
1.6
19.97
20.23
nmol/l
0.07
102
995
0
27
0.00
0.77
0.0
8.0
—
32.25
—
0
8
0
28
0.00
0.76
0.0
1.4
—
5.90
—
0
22
122
1083
1.17
0.76
3.7
3.3
748.66
1040.34
ng/l
0.78
107
932
24
175
1.39
0.76
1.9
1.3
—
—
—
0
0
413
4006
1.20
0.75
5.2
4.7
6.07
5.85
mmol/l
2.28
386
3714
42
336
1.27
0.73
3.1
2.5
69.89
72.04
ml/min/173m2
—
9
146
121
1077
1.16
0.73
3.0
2.8
331.18
338.01
umol/l
0.32
100
963
143
1290
1.15
0.72
5.0
3.7
0.02
0.01
estimate
0.15
56
465
5
27
1.86
0.68
1.0
1.0
0.94
1.14
u/l
—
5
15
7
119
0.58
0.68
5.7
3.3
138.04
99.90
mg/l
—
7
104
7
119
0.58
0.68
5.6
3.3
37.71
34.05
mg/l
—
7
104
92
810
1.17
0.64
1.7
1.7
42105718.87
26361474.87
pmol/l
0.13
76
698
130
1175
1.15
0.64
1.6
1.4
3.44
2.03
u/ml
0.24
36
329
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
30
1.67
0.61
1.0
1.2
—
—
—
0
0
9
138
0.65
0.61
2.3
2.3
531.48
306.89
ug/l
—
9
131
19
139
1.38
0.61
1.5
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
116
1048
1.14
0.58
4.3
3.6
1.02
1.02
kg/l
0.76
87
710
6
35
1.72
0.58
2.0
1.3
16902.00
24298.84
e6/l
—
6
25
12
172
0.69
0.57
1.0
1.1
0.85
0.89
g/l
0.20
12
172
14
98
1.44
0.57
8.9
8.4
634.40
434.80
iu/ml
—
5
15
9
60
1.51
0.54
1.0
1.2
99.00
97.22
%
—
9
55
57
491
1.18
0.53
5.2
4.4
31.62
31.57
%
0.01
37
338
6
39
1.55
0.53
1.3
1.9
—
—
—
0
0
6
39
1.55
0.53
1.3
1.9
—
—
—
0
0
6
39
1.55
0.53
3.0
2.3
15.20
21.76
ug/l
—
6
39
6
39
1.55
0.53
1.3
1.9
—
—
—
0
0
12
83
1.46
0.52
5.0
2.6
12.52
7.36
pmol/l
1.14
12
83
21
162
1.31
0.51
1.5
1.5
—
—
—
0
0
12
167
0.71
0.50
1.0
1.1
1.45
1.55
g/l
0.71
12
167
51
438
1.18
0.50
5.2
6.7
—
—
—
0
0
17
128
1.34
0.48
1.2
1.4
271.86
312.47
ug/g
—
10
81
7
48
1.46
0.47
1.4
2.1
—
—
—
0
0
18
139
1.31
0.44
1.1
1.2
—
3.70
—
0
5
21
166
1.28
0.44
1.8
1.9
—
—
—
0
0
422
4141
1.14
0.43
5.0
4.8
4.51
4.64
mmol/l
2.12
391
3908
5
31
1.62
0.43
4.6
2.6
—
—
—
0
0
426
4185
1.14
0.41
5.6
5.4
2.67
2.74
mmol/l
0.93
396
3936
0
17
0.00
0.40
0.0
2.8
—
40.36
—
0
17
0
18
0.00
0.40
0.0
1.8
—
201.44
—
0
18
8
61
1.32
0.39
1.6
1.3
—
—
—
0
0
8
61
1.32
0.39
1.6
1.3
—
—
—
0
0
38
326
1.18
0.39
1.9
1.4
—
—
—
0
0
146
1369
1.09
0.39
2.7
3.4
2.35
2.35
mmol/l
0.30
136
1255
16
128
1.26
0.32
3.0
3.0
—
—
—
0
0
399
3920
1.10
0.32
4.2
4.1
1.40
1.26
mmol/l
3.75
366
3665
7
54
1.30
0.30
1.4
2.0
—
—
—
0
0
7
54
1.30
0.30
2.0
1.7
—
—
—
0
0
20
166
1.21
0.30
1.5
1.6
—
—
—
0
0
45
402
1.13
0.30
3.9
2.9
—
—
—
0
0
418
4121
1.10
0.28
5.0
4.7
1.38
1.46
mmol/l
4.00
390
3866
16
194
0.82
0.28
1.3
1.8
5.82
6.15
iu/ml
—
5
48
8
62
1.30
0.28
1.6
1.3
—
—
—
0
0
8
62
1.30
0.28
1.6
1.3
—
—
—
0
0
8
62
1.30
0.28
1.6
1.3
—
—
—
0
0
8
62
1.30
0.28
1.6
1.3
—
—
—
0
0
9
117
0.76
0.27
1.7
2.1
208.22
223.17
pmol/l
—
9
111
13
104
1.26
0.26
2.0
1.3
—
—
—
0
0
5
71
0.70
0.26
2.6
1.5
—
—
—
0
0
15
123
1.23
0.25
1.5
1.5
78.01
52.95
ug/l
0.75
15
123
9
74
1.22
0.25
1.9
1.9
—
—
—
0
0
9
75
1.20
0.25
1.0
1.1
123.22
119.07
%
—
9
70
87
816
1.08
0.24
1.3
1.3
5.99
9.76
u/ml
0.49
36
324
371
3649
1.07
0.24
24.4
18.7
332.63
332.91
g/l
0.23
371
3629
36
323
1.12
0.23
1.8
1.2
252.48
298.52
u/ml
0.12
31
303
5
38
1.32
0.23
1.8
1.2
—
—
—
0
0
5
39
1.28
0.23
3.4
1.6
—
—
—
0
0
5
39
1.28
0.23
1.8
1.2
—
—
—
0
0
7
92
0.76
0.22
1.1
2.6
1.37
0.90
nmol/l
—
7
83
5
40
1.25
0.22
8.0
3.2
2.48
3.68
nmol/l
—
5
40
10
79
1.27
0.22
1.8
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
95.00
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
8
101
0.79
0.21
2.5
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
50
1.20
0.20
1.0
1.1
—
—
—
0
0
10
81
1.24
0.19
1.0
1.1
—
—
—
0
0
13
110
1.19
0.17
2.1
1.7
—
—
—
0
0
10
82
1.22
0.17
1.9
1.5
—
—
—
0
0
308
3029
1.05
0.16
3.5
3.4
46.53
43.34
u/l
0.30
289
2895
11
130
0.84
0.16
1.3
1.1
—
—
—
0
0
6
80
0.75
0.15
2.5
1.5
—
—
—
0
0
9
78
1.16
0.15
5.1
3.5
—
974.17
—
0
6
12
140
0.85
0.15
1.2
1.3
—
—
—
0
0
228
2232
1.04
0.15
3.7
3.1
95.88
111.10
ug/l
0.71
210
2105
7
89
0.78
0.14
2.1
1.5
—
—
—
0
0
14
160
0.87
0.14
1.1
1.4
—
—
—
0
0
52
490
1.07
0.14
2.4
2.0
—
—
—
0
0
25
273
0.91
0.13
1.5
1.3
—
—
—
0
0
22
242
0.90
0.13
1.3
1.5
—
—
—
0
0
90
867
1.05
0.12
1.3
1.3
19.02
29.35
iu/ml
0.93
28
267
14
157
0.89
0.11
1.9
2.0
45.50
40.44
nmol/l
0.22
14
152
37
392
0.94
0.10
2.1
2.4
13.19
13.60
nmol/l
0.07
32
361
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
5
47
1.06
0.09
1.2
1.1
—
—
—
0
0
16
145
1.11
0.09
2.2
1.7
—
—
—
0
0
5
48
1.04
0.09
2.2
1.6
—
—
—
0
0
11
124
0.88
0.09
1.5
2.6
8.51
12.15
mg/l
1.27
11
117
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
6
55
1.09
0.09
1.0
1.4
—
—
—
0
0
6
56
1.07
0.08
2.7
1.9
14.15
13.22
%
—
6
56
6
58
1.03
0.08
1.2
1.2
—
—
—
0
0
118
1207
0.97
0.08
5.4
5.1
1.72
2.08
ug/l
0.60
111
1102
77
747
1.04
0.08
2.8
3.0
0.66
0.73
ug/l
0.55
51
455
6
75
0.80
0.07
1.0
1.3
—
—
—
0
0
6
75
0.80
0.07
1.0
1.3
—
—
—
0
0
9
101
0.89
0.06
1.8
1.5
0.43
0.34
nmol/l
—
9
82
41
394
1.04
0.06
2.1
2.7
0.22
0.22
g/l
0.19
35
373
97
990
0.97
0.06
3.5
4.4
21.39
21.45
%
0.01
48
449
18
192
0.94
0.05
1.4
1.5
1.00
1.15
ratio
0.55
12
127
18
192
0.94
0.05
1.4
1.5
0.86
0.96
ratio
0.80
11
127
18
192
0.94
0.05
1.4
1.5
1.56
1.11
ratio
0.58
11
127
12
130
0.92
0.04
1.2
1.1
—
—
—
0
0
78
765
1.02
0.04
2.2
2.7
2.43
2.44
mmol/l
0.58
73
685
79
776
1.02
0.04
1.7
1.5
—
—
—
0
0
20
190
1.05
0.04
1.3
1.3
112.73
287.95
miu/ml
—
7
96
11
119
0.92
0.04
1.1
1.2
—
—
—
0
0
27
261
1.04
0.02
1.0
1.0
—
—
—
0
0
18
188
0.96
0.02
1.4
1.5
—
—
—
0
0
11
117
0.94
0.01
1.2
1.4
332.67
234.75
u/ml
—
6
68
12
114
1.05
0.00
2.2
1.8
—
—
—
0
0
10
104
0.96
0.00
1.4
2.0
—
—
—
0
0
10
104
0.96
0.00
1.4
1.2
—
—
—
0
0
11
113
0.97
0.00
1.8
1.5
—
—
—
0
0
35
347
1.01
0.00
1.1
1.3
65.17
162.02
u/ml
—
6
140
41
409
1.00
0.00
2.3
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
9.1
—
10.49
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.1
—
—
—
0
0
7
72
0.97
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.84
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
11.28
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
1.9
1.4
—
—
—
0
0
7
71
0.99
-0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
5.88
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
8
83
0.96
-0.00
2.6
4.5
24.50
30.59
mg/l
—
8
60
7
70
1.00
-0.00
1.3
1.3
—
212.50
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXT_CELLUL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_CELLUL | 1.286 [0.98, 1.69] | 0.072 |
| Birth year | 0.997 [0.99, 1.01] | 0.431 |
During the follow-up period (1.1.1998 — 31.12.2019), 106 out of 1652 females with H8_EXT_CELLUL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_CELLUL | 1.705 [1.31, 2.22] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 161 out of 1500 males with H8_EXT_CELLUL died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXT_CELLUL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.121% | 0.288% |
| 5 | 0.819% | 1.834% |
| 10 | 1.902% | 4.388% |
| 15 | 3.84% | 7.828% |
| 20 | 6.629% | 12.988% |
Relationships between endpoints
↥Index endpoint: H8_EXT_CELLUL – Cellulitis of external ear
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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