No definition available.
Congenital malformations of the nervous system
DOID EFO Endpoint Browser PheWeb
Q17_CONGEN_MALFO_NERVOUS_SYSTEM
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
913 |
4. Check minimum number of eventsNone |
913 |
5. Include endpoints |
986 |
6. Filter based on genotype QC (FinnGen only) |
876 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q
- Name in latin
- Malformationes congenitae systematis nervosi
Similar endpoints
↥List of similar endpoints to
Congenital malformations of the nervous system
based on the number of shared cases.
Similar with more cases:
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10956 | 5699 | 5233 |
| Only index persons | 8283 | 4517 | 3766 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.16 | 0.15 |
| Only index persons | 0.16 | 0.17 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 10.11 | 14.17 | 5.54 |
| Only index persons | 14.66 | 19.57 | 8.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 876 | 601 | 275 |
| Unadjusted period prevalence (%) | 0.19 | 0.21 | 0.13 |
| Median age at first event (years) | 30.07 | 31.92 | 26.02 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 920
- Matched controls
- 9200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q07.0
ICD-10 Finland
Arnold-Chiari syndrome
+∞
307.7
357
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.6
122.8
175
245
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
13.7
115.0
112
92
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
62.5
114.9
64
11
ABE50
NOMESCO Finland
Occipitocervical decompression
+∞
110.7
104
*
N03AX14
ATC
levetiracetam; systemic
11.2
99.2
110
110
G91.1
ICD-10 Finland
Obstructive hydrocephalus
39.3
95.7
59
16
Q04.8
ICD-10 Finland
Other specified congenital malformations of brain
+∞
92.3
87
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.4
90.0
208
469
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.2
88.3
216
511
N03AF02
ATC
oxcarbazepine; oral
8.0
82.7
120
169
G40.9
ICD-10 Finland
Epilepsy, unspecified
8.4
80.6
111
147
183
Kela drug reimbursment
Lamotrigin and topiramate
14.5
74.9
69
51
N05BA09
ATC
clobazam; oral
15.6
72.2
64
44
N03AX18
ATC
lacosamide; systemic
17.9
65.6
54
32
AA1AD
NOMESCO Finland
CT of head and brain
3.5
64.0
300
1118
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
6.0
63.4
121
226
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
11.4
62.5
67
63
G91.0
ICD-10 Finland
Communicating hydrocephalus
30.6
61.9
41
14
Q04.6
ICD-10 Finland
Congenital cerebral cysts
+∞
56.9
54
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
10.8
56.1
62
61
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
19.5
52.0
41
22
R51.80
ICD-10 Finland
Headache
3.1
50.8
294
1221
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
140.4
50.4
53
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
13.5
47.1
45
35
XA800
NOMESCO Finland
Neuropsychological investigation
4.7
46.0
117
279
Q03.9
ICD-10 Finland
Congenital hydrocephalus, unspecified
+∞
44.1
42
*
N03AX11
ATC
topiramate; oral
6.3
43.2
76
130
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.7
42.4
61
84
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
14.0
41.9
39
29
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
80.7
41.3
46
6
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
39.9
38
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.3
39.0
109
279
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
9.5
35.9
43
47
7423A
ICD-9 Finland
Other congenital anomalies of nervous system, Congenital hydrocephalus
+∞
35.7
34
*
Q07.8
ICD-10 Finland
Other specified congenital malformations of nervous system
+∞
35.7
34
*
XKC03
NOMESCO Finland
Water cystometry
7.2
35.5
54
79
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
7.9
35.1
49
65
G93.0
ICD-10 Finland
Cerebral cysts
40.9
34.6
43
11
74200
ICD-8 Finland
Congenital hydrocephalus, Communicans
+∞
34.6
33
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.6
34.0
121
367
Q05.7
ICD-10 Finland
Lumbar spina bifida without hydrocephalus
+∞
33.5
32
*
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
11.3
33.0
35
32
N03AG01
ATC
valproic acid; systemic, rectal
3.8
33.0
110
319
G40
ICD-10 Finland
Epilepsy
10.7
32.6
36
35
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
32.4
189
768
N05CD08
ATC
midazolam; nasal, systemic
6.5
32.1
54
88
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
31.3
252
1201
2133
FHL
Suntin revisio
323.4
31.0
31
*
N88
ICPC
Epilepsy
11.4
30.4
32
29
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.1
30.3
145
527
R42
ICD-10 Finland
Dizziness and giddiness
2.6
30.2
221
1005
N03AX09
ATC
lamotrigine; oral
3.7
29.9
104
310
74209
ICD-8 Finland
Congenital hydrocephalus, Unspecified
+∞
29.3
28
*
Q06.8
ICD-10 Finland
Other specified congenital malformations of spinal cord
+∞
29.3
28
*
Q03.0
ICD-10 Finland
Malformations of aqueduct of Sylvius
+∞
29.3
28
*
Q05.9
ICD-10 Finland
Spina bifida, unspecified
301.0
28.9
29
*
M03BX01
ATC
baclofen; systemic
7.2
28.6
43
62
N03AX12
ATC
[U] gabapentin; oral
2.8
28.6
164
658
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
28.5
108
340
L89
ICD-10 Finland
Decubitus ulcer and pressure area
10.3
28.4
32
32
7410D
ICD-9 Finland
Spina bifida, With hydrocephalus[SPINA BIFIDA APERTA CUM HYDROCEPHALO REG LUMBALIS]
+∞
28.3
27
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.7
28.2
67
150
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
48.8
27.6
33
7
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
34.2
25.7
33
10
F83
ICD-10 Finland
Mixed specific developmental disorders
6.1
25.5
45
77
Q01.8
ICD-10 Finland
Encephalocele of other sites
+∞
25.1
24
*
Q02
ICD-10 Finland
Microcephaly
+∞
25.1
24
*
H47.2
ICD-10 Finland
Optic atrophy
30.1
24.2
32
11
N05BA01
ATC
diazepam; systemic, rectal
2.8
24.1
137
544
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
5.2
24.0
50
100
XKD06
NOMESCO Finland
Physiologic investigation of micturition
6.4
23.8
40
65
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.5
23.6
60
142
ZXE20
NOMESCO Finland
More than three and less than five hours
2.7
22.9
139
571
AA1AA
NOMESCO Finland
Head X-ray examination
8.3
22.7
30
37
R20.2
ICD-10 Finland
Paraesthesia of skin
3.1
22.4
101
353
UKC02
NOMESCO Finland
Cystoscopy
3.0
22.1
109
400
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
64.2
21.9
25
*
R4120
NOMESCO Finland
Occupational therapy
3.1
21.7
95
326
N03AX16
ATC
[U] pregabalin
2.3
21.7
196
967
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
51.3
21.2
25
5
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
20.9
230
1227
2132
FHL
Ventricular operators sunt
+∞
20.9
20
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
20.9
116
454
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
20.9
267
1509
N03AF01
ATC
carbamazepine; oral, rectal
4.0
20.8
61
161
L28
ICPC
Limited function/disability (L)
2.5
20.5
150
672
Q04.9
ICD-10 Finland
Congenital malformation of brain, unspecified
+∞
19.9
19
*
Q04.3
ICD-10 Finland
Other reduction deformities of brain
+∞
19.9
19
*
P85
ICPC
Mental retardation
8.3
19.7
26
32
N03AX22
ATC
perampanel; oral
22.2
19.6
28
13
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
16.0
19.4
31
20
G40.10
ICD-10 Finland
Simple partial seizures
16.0
19.4
31
20
Z3226
NOMESCO Finland
Physiotherapist
2.2
19.3
202
1054
Z31.5
ICD-10 Finland
Genetic counselling
2.8
19.2
101
384
N03AE01
ATC
clonazepam; systemic
3.6
19.1
64
185
R62.0
ICD-10 Finland
Delayed milestone
4.6
19.1
46
104
XKD00
NOMESCO Finland
Uroflowmetry
3.0
19.1
90
322
G04AC01, ,
ATC
5.1
18.9
40
81
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.7
18.9
110
441
F82
ICD-10 Finland
Specific developmental disorder of motor function
6.0
18.5
33
57
G44.2
ICD-10 Finland
Tension-type headache
2.2
18.4
173
862
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
18.4
309
1908
N28
ICPC
Limited function/disability (N)
7.3
18.3
27
38
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.1
18.3
82
285
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.9
18.2
33
58
Z2445
NOMESCO Finland
Psychologist
2.8
18.0
95
361
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
14.1
17.9
30
22
TAB00
NOMESCO Finland
Lumbar puncture
3.3
17.8
71
230
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
17.7
110
455
G91.8
ICD-10 Finland
Other hydrocephalus
37.5
17.7
22
6
WX402
NOMESCO Finland
General anaesthesia
2.0
17.6
249
1446
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
6.7
17.6
28
43
H53.4
ICD-10 Finland
Visual field defects
5.7
17.5
33
60
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
17.5
130
585
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
5.3
17.3
35
68
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.3
17.3
35
68
G04BD04
ATC
oxybutynin; oral, transdermal
3.6
17.3
59
173
R51
ICD-10 Finland
Headache
2.8
17.2
94
364
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.0
16.9
76
264
N03AX23
ATC
brivaracetam; systemic
22.4
16.9
24
11
J01XE01
ATC
nitrofurantoin; oral
6.4
16.8
28
45
AAJ20
NOMESCO Finland
Excision of epileptic focus
64.6
16.8
19
*
Q07.9
ICD-10 Finland
Congenital malformation of nervous system, unspecified
+∞
16.7
16
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
16.4
332
2160
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
16.4
197
1076
R4110
NOMESCO Finland
Physiotherapy
1.9
16.4
261
1573
A28
ICPC
Limited function/disability NOS
2.5
16.2
115
506
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
30.6
16.2
21
7
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.3
16.0
27
44
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
15.9
191
1042
G04BD07
ATC
tolterodine; oral
4.3
15.9
41
98
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
16.0
15.8
25
16
N03AX15
ATC
zonisamide; oral
16.0
15.8
25
16
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
+∞
15.7
15
*
Q06.9
ICD-10 Finland
Congenital malformation of spinal cord, unspecified
+∞
15.7
15
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.1
15.6
67
227
R15
ICD-10 Finland
Faecal incontinence
5.1
15.3
32
64
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
45.8
15.1
18
*
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
45.8
15.1
18
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
14.8
132
641
7419D
ICD-9 Finland
Spina bifida, Without mention of hydrocephalus[SPINA BIFIDA APERTA SINE HYDROCEPHALO REG LUMBALIS]
+∞
14.6
14
*
Q04.00
ICD-10 Finland
Agenesis of corpus callosum
+∞
14.6
14
*
Q05.0
ICD-10 Finland
Cervical spina bifida with hydrocephalus
+∞
14.6
14
*
TKC22
NOMESCO Finland
Catheterisation instruction
6.7
14.5
23
35
SPAT1229
SPAT
Assessment of need for aid
3.3
14.4
55
173
204
Kela drug reimbursment
Leukemia lymphatica
4.2
14.4
39
97
N06AX21
ATC
duloxetine; oral
2.2
13.6
125
614
Q05.8
ICD-10 Finland
Sacral spina bifida without hydrocephalus
+∞
13.6
13
*
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.7
13.6
76
298
S97
ICPC
Chronic ulcer skin
3.4
13.4
50
155
M41.4
ICD-10 Finland
Neuromuscular scoliosis
18.6
13.4
20
11
H50.1
ICD-10 Finland
Divergent concomitant strabismus
11.7
13.3
24
21
H53.2
ICD-10 Finland
Diplopia
4.1
13.3
37
94
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.3
13.2
111
525
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.3
13.2
112
532
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
12.4
13.1
23
19
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.9
13.1
29
61
AAF00
NOMESCO Finland
Ventriculostomy
15.3
13.1
21
14
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
15.3
13.1
21
14
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.7
13.0
71
275
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
50.7
12.9
15
*
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.6
12.7
30
67
74101
ICD-8 Finland
Spina bifida, Cum hydrocephalo, non cute tecta
+∞
12.5
12
*
74201
ICD-8 Finland
Congenital hydrocephalus, Non communicans
+∞
12.5
12
*
Q03.1
ICD-10 Finland
Atresia of foramina of Magendie and Luschka
+∞
12.5
12
*
3069, ,
Kela drug reimbursment
+∞
12.5
12
*
Q01.1
ICD-10 Finland
Nasofrontal encephalocele
+∞
12.5
12
*
1541, ,
Kela drug reimbursment
+∞
12.5
12
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.3
12.5
48
152
Z2446
NOMESCO Finland
Social worker
2.2
12.5
109
524
N29
ICPC
Neurological sympt/complt other
4.9
12.4
27
56
R11
ICD-10 Finland
Nausea and vomiting
2.2
12.4
114
560
Q66.0
ICD-10 Finland
Talipes equinovarus
27.1
12.1
16
6
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
9.4
12.0
24
26
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
12.0
58
210
G40.89
ICD-10 Finland
Other epilepsy
13.6
12.0
20
15
N99
ICPC
Neurological disease other
9.1
11.8
24
27
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
11.8
217
1352
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
16.7
11.7
18
11
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
16.7
11.7
18
11
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
12.7
11.7
20
16
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
23.2
11.6
16
7
TJF80
NOMESCO Finland
Ostomy education
10.2
11.5
22
22
RS222, ,
NOMESCO Finland
5.1
11.5
24
48
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
11.5
110
548
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
11.5
154
867
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.9
11.5
25
52
Q05.3
ICD-10 Finland
Sacral spina bifida with hydrocephalus
+∞
11.5
11
*
N02AX02
ATC
tramadol; systemic, rectal
1.7
11.4
303
2088
J01EA01
ATC
trimethoprim; systemic
1.8
11.4
220
1389
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.8
11.3
57
211
SPAT1216
SPAT
Assessment of functional ability
2.2
11.3
104
510
G04BD08
ATC
solifenacin; oral
3.1
11.1
47
158
G44.8
ICD-10 Finland
Other specified headache syndromes
4.0
11.1
31
79
WX882
NOMESCO Finland
High dependency care
2.8
11.1
57
214
N02BF01
ATC
gabapentin; oral
2.2
11.1
92
433
A02BC01
ATC
omeprazole; systemic
1.8
11.0
208
1304
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
10.9
140
777
Z3231
NOMESCO Finland
Registered nurse
1.7
10.9
261
1747
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
10.6
95
460
ZXD05
NOMESCO Finland
Urgent procedure
1.7
10.6
267
1806
N03AX25
ATC
cenobamate; oral
60.7
10.6
12
*
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
10.6
100
496
N03AG04
ATC
vigabatrin; oral
14.4
10.5
17
12
N03AF03
ATC
rufinamide; oral
111.2
10.4
11
*
3314A
ICD-9 Finland
Other cerebral degenerations, Obstructive hydrocephalus
111.2
10.4
11
*
74190
ICD-8 Finland
Spina bifida, Hydrocephalo non indicato, cute tecta
+∞
10.4
10
*
ABE99
NOMESCO Finland
Other operation for spinal malformation
+∞
10.4
10
*
74210, ,
ICD-8 Finland
+∞
10.4
10
*
74100
ICD-8 Finland
Spina bifida, Cum hydrocephalo, cute tecta
+∞
10.4
10
*
AAF40
NOMESCO Finland
Shunt of cyst of brain to peritoneum
+∞
10.4
10
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.5
10.4
20
37
G43.9
ICD-10 Finland
Migraine, unspecified
2.2
10.4
97
478
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
10.4
203
1282
G03.9
ICD-10 Finland
Meningitis, unspecified
16.2
10.4
16
10
XCK00
NOMESCO Finland
Perimetry
2.9
10.3
47
165
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
10.3
103
522
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
23.7
10.3
14
6
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
10.2
134
747
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.3
10.2
76
341
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
10.2
238
1577
1530
FHL
Urethrocystoscopy
8.0
10.1
22
28
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.4
10.1
36
109
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
9.3
10.0
20
22
S06.0
ICD-10 Finland
Concussion
2.0
10.0
125
685
SPAT1255
SPAT
Intravenous administration of medicine
2.8
10.0
51
191
181
Kela drug reimbursment
Retigabine and vigabatrin
16.9
9.9
15
9
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.5
9.9
61
251
S18
ICPC
Laceration/cut
1.6
9.9
376
2806
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
9.8
82
387
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.0
9.8
109
575
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
9.7
198
1262
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
13.5
9.7
16
12
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.1
9.7
41
138
H01AC01
ATC
somatropin; parenteral
4.0
9.6
27
69
H50.0
ICD-10 Finland
Convergent concomitant strabismus
4.4
9.6
24
56
KH1EE
NOMESCO Finland
Urologic ultrasound examination
15.2
9.5
15
10
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
15.2
9.5
15
10
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
15.2
9.5
15
10
Q04.08
ICD-10 Finland
Congenital malformations of corpus callosum
+∞
9.4
9
*
74199
ICD-8 Finland
Spina bifida, Without mention of hydrocephalus
+∞
9.4
9
*
Q00.0
ICD-10 Finland
Anencephaly
+∞
9.4
9
*
N03AB02
ATC
phenytoin; systemic
8.2
9.4
20
25
ZXA05
NOMESCO Finland
Left side
1.8
9.3
154
924
N03AF04
ATC
eslicarbazepine; oral
37.1
9.0
11
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
24.3
8.9
12
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.8
353
2646
G43.3
ICD-10 Finland
Complicated migraine
3.3
8.8
33
103
L01
ICPC
Neck symptom/complaint
1.7
8.8
164
1018
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
8.8
116
648
N06AX16
ATC
venlafaxine; oral
1.8
8.8
145
869
ZXE00
NOMESCO Finland
One hour or less
1.5
8.8
344
2567
A06AD11
ATC
lactulose; oral
2.1
8.7
87
440
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
8.3
8.6
18
22
AAF15
NOMESCO Finland
Ventriculoatrial shunt
27.8
8.5
11
*
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
20.2
8.5
12
6
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.6
8.4
27
76
-, ,
ICD-10 Finland
4.4
8.4
21
49
L82
ICPC
Congenital anomaly musculoskeletal
90.9
8.4
9
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
8.4
124
717
ZXD35
NOMESCO Finland
Usual procedure
3.4
8.4
30
91
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
12.9
8.4
14
11
H50.31
ICD-10 Finland
Intermittent exotropia
3.8
8.4
25
67
7410B
ICD-9 Finland
Spina bifida, With hydrocephalus[SPINA BIFIDA APERTA CUM HYDROCEPHALO REG CERVIC]
+∞
8.3
8
*
Q03.88
ICD-10 Finland
Other congenital hydrocephalus
+∞
8.3
8
*
74191
ICD-8 Finland
Spina bifida, Hydrocephalo non indicato, non ente tecta
+∞
8.3
8
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
8.3
325
2417
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.1
8.3
75
365
R1260
NOMESCO Finland
Evaluation of communicative skills
4.1
8.3
22
54
3007
Kela drug reimbursment
Erenumab and fremanezumab
3.9
8.3
24
63
R1250
NOMESCO Finland
Evaluation of functional capability
3.3
8.3
31
97
WX704
NOMESCO Finland
Intubation
2.1
8.2
77
380
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.3
8.2
21
50
R5110, ,
SPAT
2.4
8.2
56
242
H50.30
ICD-10 Finland
Intermittent esotropy
4.8
8.1
18
38
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
8.1
61
275
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
8.1
81
410
SPAT1153
SPAT
Removal of sutures
1.6
8.1
205
1378
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.7
8.1
169
1081
AAF50
NOMESCO Finland
Third ventriculostomy
33.7
8.1
10
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
8.1
133
796
TJD20
NOMESCO Finland
Change of gastrostomy tube
7.3
8.0
18
25
R52.2
ICD-10 Finland
Other chronic pain
2.8
8.0
39
143
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.8
7.9
24
65
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
7.9
685
5985
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
13.2
7.9
13
10
ZXC40
NOMESCO Finland
Use of ultrasound
9.5
7.8
15
16
SPAT1260
SPAT
Consultation of another employee
1.7
7.8
145
898
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.7
7.8
24
66
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.3
7.8
60
274
M35.7
ICD-10 Finland
Hypermobility syndrome
3.6
7.7
25
71
R5599
NOMESCO Finland
Other rehabilitation service
2.8
7.7
37
134
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
45.4
7.7
9
*
R55
ICD-10 Finland
Syncope and collapse
2.1
7.7
78
397
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
7.6
76
384
ZXA00
NOMESCO Finland
Right side
1.7
7.6
164
1056
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.2
7.6
66
316
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.7
7.6
24
67
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
18.5
7.6
11
6
R33
ICD-10 Finland
Retention of urine
2.6
7.6
42
164
602
Kela drug reimbursment
Children's severe malnutrition
3.4
7.6
26
77
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
7.2
7.5
17
24
WX730
NOMESCO Finland
Conventional respirator
4.5
7.5
18
41
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
7.4
87
466
C03CA01
ATC
furosemide; systemic
1.8
7.4
127
767
7545B
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES EQUINOVARUS CONGENITUS]
80.7
7.4
8
*
199
Kela drug reimbursment
Rufinamide
80.7
7.4
8
*
7424A
ICD-9 Finland
Other congenital anomalies of nervous system, Other specified anomalies of brain
80.7
7.4
8
*
WX892
NOMESCO Finland
Monitored bed care
2.1
7.4
67
327
M79.6
ICD-10 Finland
Pain in limb
1.5
7.4
364
2825
H52.2
ICD-10 Finland
Astigmatism
2.8
7.4
36
132
A02BC02
ATC
pantoprazole; systemic
1.5
7.3
485
3983
Q01.9
ICD-10 Finland
Encephalocele, unspecified
+∞
7.3
7
*
Q06.3
ICD-10 Finland
Other congenital cauda equina malformations
+∞
7.3
7
*
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
7.3
7
*
Q04.4
ICD-10 Finland
Septo-optic dysplasia
+∞
7.3
7
*
R32
ICD-10 Finland
Unspecified urinary incontinence
3.4
7.3
26
79
RT150, ,
NOMESCO Finland
5.9
7.2
19
33
N06AA09
ATC
amitriptyline; systemic
2.2
7.2
60
283
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
7.2
397
3144
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.6
7.2
40
157
M05BA04
ATC
alendronic acid; oral
2.6
7.2
40
157
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.3
7.1
55
251
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.1
7.1
70
352
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
20.2
7.1
10
5
M41.5
ICD-10 Finland
Other secondary scoliosis
20.2
7.1
10
5
RL140, ,
NOMESCO Finland
6.6
7.1
17
26
9165
FHL
Removal of osteosynthesis material
4.2
7.0
18
43
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.4
7.0
17
39
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.0
246
1778
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.9
7.0
31
108
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
6.9
341
2638
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
4.2
6.8
18
44
101
Kela drug reimbursment
Anterior pituitary hypofunction
3.8
6.8
20
53
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
11.0
6.8
12
11
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.2
6.8
59
283
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.7
6.8
35
132
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
4.3
6.8
17
40
G82.1
ICD-10 Finland
Spastic paraplegia
40.4
6.8
8
*
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
40.4
6.8
8
*
G81.1
ICD-10 Finland
Spastic hemiplegia
16.8
6.8
10
6
ZXC86
NOMESCO Finland
Use of endoscopic device
16.8
6.8
10
6
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.3
6.7
25
78
N02CD03
ATC
fremanezumab; systemic
3.9
6.7
19
49
Z2221
NOMESCO Finland
Medical doctor
1.5
6.7
238
1721
KDV20
NOMESCO Finland
Submucous urethral injection
22.7
6.7
9
*
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
7.9
6.6
14
18
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
6.6
148
962
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.6
6.6
37
146
R52.9
ICD-10 Finland
Pain, unspecified
1.8
6.6
96
553
R4190
NOMESCO Finland
Nutritional therapy
2.0
6.6
71
370
ZYC01
NOMESCO Finland
Remote contact by phone
2.0
6.6
68
349
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
8.8
6.6
13
15
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.1
6.5
27
90
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
6.5
97
562
R4130
NOMESCO Finland
Speech therapy
2.6
6.5
36
141
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
4.0
6.5
18
46
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.4
726
6525
A03FA02
ATC
cisapride; oral, rectal
2.3
6.4
47
210
ZY010
NOMESCO Finland
Hospital outpatient
1.9
6.4
76
409
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.1
6.4
57
276
34532
ICD-8 Finland
Epilepsy, Partialis (focalis) generalisata
70.3
6.4
7
*
3431A
ICD-9 Finland
Infantile cerebral palsy, Hemiplegic
70.3
6.4
7
*
AB4AE
NOMESCO Finland
Spinal ultrasound examination
70.3
6.4
7
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
6.4
68
352
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.1
6.4
56
270
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.8
6.4
19
51
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.7
6.4
33
125
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
5.6
6.3
17
31
ZXA10
NOMESCO Finland
Bilateral
1.7
6.3
136
875
A01
ICPC
Pain general/multiple sites
1.9
6.3
85
478
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
9.3
6.3
12
13
Z50.1
ICD-10 Finland
Other physical therapy
2.4
6.3
40
168
3360A
ICD-9 Finland
Other diseases of spinal cord, Syringomyelia and syringobulbia
+∞
6.3
6
*
Q06.4
ICD-10 Finland
Hydromyelia
+∞
6.3
6
*
2139
FHL
Other measure in this category
+∞
6.3
6
*
G91
ICD-10 Finland
Hydrocephalus
+∞
6.3
6
*
M49.4*G95.0
ICD-10 Finland
Neuropathic spondylopathy in syringomyelia and syringobulbia
+∞
6.3
6
*
G00.8
ICD-10 Finland
Other bacterial meningitis
+∞
6.3
6
*
UJF32
NOMESCO Finland
Coloscopy
1.6
6.3
150
991
G95.9
ICD-10 Finland
Disease of spinal cord, unspecified
26.9
6.2
8
*
R5130, ,
SPAT
26.9
6.2
8
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
6.2
61
307
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
7.1
6.2
14
20
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
3.7
6.2
19
52
SPAT1301
SPAT
No procedures
1.5
6.2
248
1833
G04BD11
ATC
fesoterodine; oral
5.1
6.2
18
36
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
5.4
6.2
17
32
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
5.8
6.2
16
28
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.0
6.2
26
88
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.1
150
996
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
3.8
6.1
18
48
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
4.2
6.1
16
39
H02AB06
ATC
prednisolone; systemic
1.4
6.1
342
2695
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.9
6.1
76
417
S00.0
ICD-10 Finland
Superficial injury of scalp
3.1
6.1
24
78
ZXY02
NOMESCO Finland
Neuropsychologist
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
499
3111
2.32
34.01
12.2
8.8
1.21
1.22
mmol/l
2.49
474
2918
535
3459
2.31
33.11
11.5
8.6
1.21
1.22
mmol/l
0.89
481
3065
53
94
5.92
28.94
2.5
1.9
—
—
—
0
0
89
245
3.91
28.65
1.8
3.0
609.73
414.90
mg/l
1.13
83
236
35
41
8.83
27.66
1.6
1.7
—
—
—
0
0
326
1848
2.18
26.30
2.7
2.2
223.61
218.27
u/l
0.03
313
1769
153
619
2.77
26.10
11.8
10.9
16.00
13.18
kpa
5.09
148
593
153
619
2.77
26.10
11.8
10.9
5.22
5.15
kpa
0.37
148
591
35
46
7.87
25.20
2.0
2.6
—
—
—
0
0
150
612
2.73
25.12
11.9
10.9
0.29
0.54
mmol/l
0.25
111
506
78
227
3.66
23.11
1.7
3.0
3.51
3.55
mmol/l
0.12
73
217
77
228
3.59
22.23
2.0
3.3
52.53
10.77
e6/l
1.05
57
160
77
232
3.53
21.64
2.0
3.3
8755.80
225.75
e6/l
0.49
59
170
583
4289
1.98
21.35
8.2
6.0
6.06
6.33
mmol/l
3.14
561
3954
53
139
3.98
18.18
6.9
6.8
452.60
388.32
umol/l
1.72
48
128
417
2874
1.82
17.33
6.0
5.6
37.33
37.20
g/l
0.19
389
2725
38
86
4.57
15.78
8.3
8.6
10.43
9.79
mg/l
0.28
32
81
299
1922
1.82
15.15
5.0
5.4
93.27
92.44
%
0.27
289
1878
854
7582
2.76
15.04
22.0
13.7
139.40
139.59
mmol/l
1.49
840
7420
854
7589
2.75
14.88
21.6
13.7
3.94
3.93
mmol/l
0.29
837
7404
59
193
3.20
14.55
2.2
2.3
412.66
208.39
ug/l
0.62
49
178
374
2597
1.74
14.39
10.5
8.8
1.12
1.12
inr
0.01
318
2164
664
5424
1.81
14.11
7.6
7.2
85.20
84.14
u/l
0.16
638
5155
340
2317
1.74
13.86
3.1
3.0
2.36
2.36
mmol/l
0.16
313
2142
473
3535
1.70
13.68
3.3
2.8
74.45
72.47
nmol/l
0.59
447
3313
116
554
2.25
13.50
14.1
11.6
95.91
95.81
%
0.04
111
537
74
288
2.71
13.39
10.4
8.4
24.53
24.23
mmol/l
0.27
69
272
588
4726
1.68
12.32
9.2
10.4
3.93
3.89
e9/l
0.17
522
4080
379
2725
1.66
12.29
2.1
1.9
96.71
97.30
pmol/l
0.09
216
1457
474
3611
1.64
12.21
6.1
6.5
12.02
13.35
umol/l
0.55
445
3427
121
617
2.11
11.91
5.9
5.2
—
—
—
0
0
280
1878
1.71
11.70
2.7
2.4
—
—
—
0
0
159
900
1.93
11.68
2.2
2.2
385.91
361.77
nmol/l
0.75
146
852
144
795
1.96
11.37
1.6
1.7
1121.53
1179.22
nmol/l
0.36
115
614
196
1217
1.78
10.65
1.6
1.6
50610215.98
42937762.68
pmol/l
0.05
164
1069
153
902
1.84
9.82
8.1
7.9
2.00
1.30
mmol/l
2.24
133
753
183
1153
1.73
9.35
5.5
5.9
0.82
0.82
mmol/l
0.14
174
1109
19
39
4.95
8.86
2.4
2.2
26.44
16.95
umol/l
2.02
19
39
301
2178
1.57
8.82
3.6
3.0
24.75
63.19
ng/l
0.55
181
1157
452
3577
1.52
8.76
3.1
2.9
—
—
estimate
—
0
0
876
8163
2.53
8.76
19.8
14.2
65.44
68.72
umol/l
2.29
870
8070
232
1586
1.62
8.61
4.1
2.6
5.84
8.09
e6/l
2.14
216
1426
169
1067
1.72
8.51
3.6
4.0
28.54
29.80
s
2.32
159
1045
165
1038
1.72
8.42
2.2
2.0
—
—
—
0
0
650
5584
1.56
8.40
4.7
4.2
9.19
9.06
mm/h
0.11
624
5276
303
2221
1.54
8.28
5.3
3.4
0.01
0.01
estimate
0.13
108
831
871
8124
2.35
8.19
12.1
10.3
25.32
26.03
u/l
0.64
858
7939
166
1057
1.70
8.08
10.6
8.7
1.16
1.16
mmol/l
0.11
156
1004
277
2005
1.55
7.95
2.5
2.5
2.87
2.60
mg/l
1.06
243
1761
244
1721
1.57
7.85
1.8
1.6
20.70
20.48
nmol/l
0.07
210
1505
319
2387
1.51
7.83
5.7
3.2
20.98
88.06
e6/l
1.44
255
1750
720
6388
1.58
7.53
5.2
4.4
14.56
14.44
pmol/l
0.70
682
5961
118
697
1.79
7.46
15.5
8.1
1.17
1.09
mmol/l
0.11
82
507
289
2139
1.51
7.39
3.1
2.7
53.92
58.82
u/l
0.94
267
2010
190
1281
1.61
7.35
4.8
2.9
1.06
0.93
e6/l
0.24
105
610
106
612
1.83
7.22
2.2
2.3
26.51
15.85
au/ml
0.61
12
65
279
2095
1.48
6.50
5.7
3.2
0.25
0.31
e6/l
0.31
218
1462
178
1215
1.58
6.48
5.1
3.1
3.06
2.86
e6/l
0.10
94
546
125
782
1.69
6.45
2.1
1.9
—
—
—
0
0
193
1352
1.54
6.25
3.8
3.9
1249.08
859.66
ng/l
0.78
159
1111
92
536
1.80
6.09
5.2
5.7
53.65
70.26
ng/l
2.94
86
497
111
683
1.71
6.08
2.6
3.3
0.21
0.22
g/l
0.48
101
649
255
1903
1.47
6.07
5.0
3.2
1.02
1.84
kg/l
0.50
157
1233
12
14
8.67
6.06
3.5
3.1
23.00
27.14
umol/l
0.48
12
14
794
7310
1.63
6.05
6.1
5.2
1.71
1.82
mu/l
2.37
755
6951
26
90
2.94
5.93
1.0
1.2
59.36
34.79
mg/l
0.69
21
69
163
1115
1.56
5.85
2.3
2.3
2.42
2.42
mmol/l
0.00
144
986
508
4315
1.40
5.76
5.7
3.5
0.00
0.01
estimate
0.80
115
822
19
55
3.51
5.75
1.1
1.3
—
—
—
0
0
61
317
1.99
5.73
1.4
1.2
0.24
0.86
u/ml
—
7
14
67
360
1.93
5.72
3.7
7.5
0.62
0.60
%
0.26
67
360
236
1753
1.47
5.71
2.4
2.5
0.81
1.18
mg/l
1.57
178
1309
119
760
1.65
5.67
2.3
1.9
—
—
—
0
0
37
158
2.40
5.63
1.7
1.7
22.18
21.92
ng/l
0.04
37
158
26
93
2.85
5.60
2.5
3.2
1.45
1.75
umol/l
1.72
26
88
504
4290
1.39
5.56
5.6
3.4
0.00
7.50
estimate
1.33
116
856
116
740
1.65
5.55
1.6
1.7
19.62
19.69
iu/l
0.01
88
596
523
4486
1.38
5.46
3.7
3.4
76.65
81.00
ug/l
0.31
498
4277
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
19
57
3.38
5.46
1.1
1.2
—
—
—
0
0
844
7943
1.76
5.31
19.7
12.6
21.00
21.04
mg/l
0.01
735
6288
38
169
2.30
5.30
1.8
1.5
—
—
—
0
0
498
4251
1.37
5.29
5.6
3.4
0.01
0.00
estimate
0.41
112
860
579
5074
1.38
5.16
7.3
4.1
436.20
389.85
e6/l
—
5
59
27
105
2.62
5.00
1.1
1.0
—
—
—
0
0
15
41
3.70
4.94
1.5
1.5
54.17
93.83
%
—
6
6
113
738
1.61
4.92
3.4
3.2
9.78
10.09
g/l
0.44
100
693
69
394
1.81
4.91
2.2
3.3
66.70
67.02
g/l
0.17
61
373
80
478
1.74
4.88
2.1
1.7
—
—
—
0
0
63
351
1.85
4.85
1.7
1.6
—
—
—
0
0
22
78
2.87
4.84
1.0
1.1
—
—
—
0
0
22
78
2.87
4.84
1.2
1.2
1.05
0.61
ratio
0.58
13
40
164
1170
1.49
4.80
3.1
2.6
13.23
14.39
umol/l
1.25
155
1102
29
120
2.46
4.75
1.8
1.5
—
—
—
0
0
140
977
1.51
4.55
3.3
2.7
20.78
23.78
%
2.11
133
923
79
484
1.69
4.42
1.6
1.9
7.61
8.42
u/l
0.27
51
351
382
3194
1.34
4.35
5.4
3.2
0.05
0.03
estimate
0.22
88
724
152
1094
1.47
4.24
3.2
2.6
2.53
2.43
g/l
1.54
141
1018
39
193
2.07
4.24
1.8
1.4
—
—
—
0
0
74
455
1.68
4.10
6.8
3.5
1.23
1.23
mmol/l
0.16
65
388
25
105
2.42
4.01
2.8
4.1
—
—
—
0
0
734
6804
1.39
3.88
13.8
10.6
98.79
93.19
ml/min/173m2
9.55
669
6018
24
101
2.41
3.84
1.0
1.0
—
—
—
0
0
330
2750
1.31
3.70
4.0
3.6
30.82
30.54
u/l
0.04
313
2623
703
6490
1.35
3.68
5.3
4.9
36.63
37.51
mmol/mol
2.15
668
6191
65
1020
0.61
3.67
1.6
1.6
1081.85
983.57
mu/l
0.34
55
888
33
165
2.04
3.53
2.4
1.4
364.92
355.88
mu/l
0.05
25
141
35
179
1.99
3.52
2.5
2.1
17.59
2.86
ug/l
0.40
30
160
104
721
1.50
3.50
2.3
2.4
26.00
103.73
u/l
0.59
87
592
127
917
1.45
3.48
3.4
4.0
4.88
6.38
umol/l
1.39
111
778
12
32
3.79
3.39
2.9
4.6
137.67
120.73
ug/l
0.10
12
32
32
162
2.01
3.33
2.3
2.4
134.29
132.23
g/l
0.16
24
135
12
33
3.67
3.30
3.4
2.7
0.96
1.10
umol/l
0.67
12
28
76
501
1.56
3.23
3.2
2.4
0.52
0.19
e6/l
0.93
70
480
8
15
5.37
3.19
3.9
8.4
45.13
39.10
umol/l
—
8
10
97
679
1.48
3.13
13.2
10.1
6.13
6.66
mmol/l
0.56
92
658
727
6804
1.33
3.04
4.4
3.9
5.60
5.67
mmol/l
0.84
683
6379
29
535
0.53
2.99
1.6
1.5
1.12
1.15
ratio
0.08
17
345
5
5
10.04
2.98
1.2
1.4
—
—
—
0
0
56
350
1.64
2.98
1.6
1.4
—
—
—
0
0
55
348
1.62
2.80
2.7
3.7
79.53
145.84
ng/l
1.71
47
317
56
357
1.61
2.77
2.3
2.2
7.37
7.30
ug/l
0.01
49
316
15
60
2.52
2.71
1.1
1.2
—
—
—
0
0
30
527
0.55
2.64
1.5
1.5
—
—
—
0
0
10
30
3.36
2.60
1.1
1.2
—
—
—
0
0
31
535
0.56
2.57
1.5
1.5
1.10
1.18
ratio
0.17
19
346
31
535
0.56
2.57
1.5
1.5
1.29
0.95
ratio
0.87
19
345
15
62
2.44
2.55
1.0
1.0
1.25
1.10
u/l
—
6
25
34
194
1.78
2.53
2.6
3.2
2.31
2.87
index
0.19
23
113
279
2371
1.25
2.51
1.8
1.6
1.91
2.00
g/l
0.51
166
1459
13
297
0.43
2.49
1.7
1.3
—
—
—
0
0
25
130
1.95
2.47
3.4
3.6
1.31
1.34
mmol/l
0.11
25
124
24
123
1.98
2.47
7.0
3.6
8.81
7.32
pmol/l
0.30
24
123
189
1535
1.29
2.46
1.3
1.3
22.97
25.07
iu/ml
0.10
61
438
23
117
1.99
2.42
5.9
2.9
4.85
4.90
kpa
0.11
23
117
82
586
1.44
2.42
1.5
1.6
317.00
309.29
mu/l
0.08
74
533
106
797
1.37
2.34
1.3
1.3
103.54
144.19
u/ml
0.85
35
323
9
29
3.12
2.23
1.0
1.2
—
—
—
0
0
9
29
3.12
2.23
1.1
1.2
—
—
—
0
0
7
19
3.70
2.15
1.0
1.0
—
—
—
0
0
200
1663
1.26
2.14
2.2
3.0
308.97
319.91
umol/l
0.84
179
1520
176
1442
1.27
2.13
2.5
2.8
111.40
101.42
ug/g
0.21
133
1163
86
1143
0.73
2.12
1.9
1.7
3.66
3.43
ratio
1.01
62
840
31
183
1.72
2.10
1.4
1.4
16.01
19.96
u/l
0.33
24
158
896
8783
1.77
2.08
28.3
19.4
267.82
261.93
e9/l
1.96
886
8619
44
659
0.65
2.08
1.4
1.5
—
—
—
0
0
305
2667
1.21
2.04
1.4
1.5
0.98
2.34
u/ml
2.72
84
678
81
598
1.39
2.02
3.2
2.7
—
—
—
0
0
10
38
2.65
2.01
1.4
5.8
105.80
201.85
umol/l
—
5
20
896
8788
1.75
2.00
28.3
19.3
4.54
4.56
e12/l
0.70
884
8601
52
355
1.49
1.97
1.7
2.1
2.39
4.73
iu/ml
2.27
12
69
20
105
1.92
1.96
1.6
1.3
—
—
—
0
0
30
483
0.61
1.96
1.6
1.7
—
—
—
0
0
12
51
2.37
1.95
1.8
2.4
—
—
—
0
0
19
99
1.94
1.91
1.5
1.3
0.49
0.52
nmol/l
0.18
19
94
35
220
1.61
1.90
1.9
2.0
—
—
—
0
0
32
197
1.65
1.89
1.6
1.8
—
—
—
0
0
9
34
2.66
1.87
2.3
1.7
—
—
—
0
0
750
7173
1.25
1.85
22.6
16.1
13.37
13.30
%
0.70
744
7096
5
12
4.18
1.82
1.2
1.2
—
—
—
0
0
19
101
1.90
1.81
3.5
3.9
7.30
7.15
mmol/l
0.04
19
96
8
29
2.77
1.79
1.1
1.3
—
—
—
0
0
34
217
1.59
1.76
1.3
1.4
308.55
341.41
ug/g
0.39
22
120
12
54
2.24
1.74
2.0
4.5
1.42
0.72
index
0.28
12
54
8
30
2.68
1.72
1.0
1.2
—
—
—
0
0
6
19
3.17
1.66
2.2
3.4
0.62
0.63
mmol/l
—
6
19
8
31
2.59
1.66
2.4
1.6
—
—
—
0
0
11
49
2.26
1.64
3.3
1.9
1.67
2.42
u/field
—
6
33
590
5547
1.18
1.60
4.1
3.4
43.67
36.63
u/l
1.11
567
5338
124
1011
1.26
1.59
3.9
4.1
1.31
1.93
ug/l
1.15
114
916
52
373
1.42
1.58
1.3
1.3
—
—
—
0
0
95
750
1.30
1.57
1.6
1.4
450.67
243.33
u/ml
0.27
85
704
8
33
2.44
1.54
1.4
1.4
—
—
—
0
0
139
1158
1.24
1.48
4.0
3.5
333.60
621.90
ng/l
0.79
84
703
20
117
1.73
1.46
2.5
3.6
598.50
545.05
e6/l
0.14
12
80
164
1396
1.21
1.42
1.3
1.3
9.88
9.64
u/ml
0.02
69
551
20
118
1.71
1.42
2.6
3.6
209.62
199.48
e6/l
0.09
13
85
11
53
2.09
1.39
1.5
2.7
1.22
1.19
mmol/l
0.39
11
53
11
53
2.09
1.39
1.5
2.7
3.95
3.99
mmol/l
0.13
11
53
11
53
2.09
1.39
1.5
2.7
105.09
106.13
mmol/l
0.36
11
53
274
2447
1.17
1.38
4.7
2.8
0.03
0.01
estimate
0.26
92
713
37
256
1.46
1.38
1.5
1.4
0.27
0.36
nmol/l
0.83
29
207
64
489
1.33
1.35
1.3
1.6
—
—
—
0
0
13
68
1.92
1.33
2.5
2.6
31.31
32.37
pg
0.22
13
68
69
878
0.77
1.31
1.6
1.6
3.67
3.43
mmol/l
0.95
44
591
30
436
0.68
1.30
2.0
1.8
—
—
—
0
0
8
34
2.36
1.29
1.4
1.4
—
—
—
0
0
8
34
2.36
1.29
2.4
1.6
—
—
—
0
0
8
34
2.36
1.29
1.1
1.5
14.75
13.18
pmol/l
—
8
29
10
48
2.10
1.28
2.9
1.7
—
—
—
0
0
5
19
2.64
1.21
2.0
1.5
—
—
—
0
0
34
239
1.44
1.19
1.5
1.2
—
—
—
0
0
26
380
0.68
1.18
1.1
1.2
5.16
2.50
u/ml
0.27
15
242
27
390
0.68
1.15
1.5
1.6
68.74
56.77
ug/l
0.52
27
390
83
674
1.25
1.14
3.7
3.7
31.48
31.42
%
0.01
65
488
27
389
0.68
1.14
1.1
1.2
5.65
5.69
u/ml
0.00
17
262
35
250
1.42
1.14
1.7
1.8
135.67
123.28
au/ml
—
9
84
45
336
1.36
1.14
1.8
1.7
6.85
6.28
u/ml
0.09
11
81
12
65
1.86
1.13
1.6
1.1
—
79.29
—
0
7
12
65
1.86
1.13
2.1
1.2
114.25
113.54
pmol/l
0.02
12
65
25
167
1.51
1.13
1.7
1.3
—
—
—
0
0
25
167
1.51
1.13
1.7
1.3
—
—
—
0
0
22
143
1.55
1.12
2.2
1.6
—
—
—
0
0
12
66
1.83
1.09
1.6
1.7
—
—
—
0
0
96
798
1.23
1.08
4.2
3.6
22.54
21.97
%
0.12
41
295
22
146
1.52
1.04
1.9
1.5
—
—
—
0
0
27
378
0.71
1.00
1.1
1.2
0.84
1.03
u/ml
0.15
13
223
7
35
2.01
1.00
1.0
1.1
86.66
97.88
nmol/l
—
7
23
14
84
1.68
0.98
1.9
1.3
—
—
—
0
0
19
124
1.54
0.97
3.0
1.7
—
—
—
0
0
7
36
1.95
0.97
2.4
1.7
—
—
—
0
0
16
100
1.61
0.97
2.5
1.8
—
—
—
0
0
33
242
1.38
0.96
1.5
1.3
34.04
10.31
u/ml
—
5
36
14
85
1.66
0.94
1.9
1.3
—
—
—
0
0
14
85
1.66
0.94
1.9
1.3
—
—
—
0
0
32
428
0.74
0.91
1.1
1.2
2.74
3.08
u/ml
0.08
19
276
6
28
2.15
0.91
2.3
1.9
—
—
—
0
0
6
28
2.15
0.91
2.3
1.9
—
—
—
0
0
15
231
0.64
0.91
1.8
1.6
—
—
—
0
0
15
94
1.61
0.91
1.5
1.3
—
—
—
0
0
21
143
1.48
0.90
1.1
1.2
—
—
—
0
0
6
29
2.08
0.89
2.3
1.9
—
—
—
0
0
6
29
2.08
0.89
3.2
5.9
—
—
—
0
0
39
298
1.32
0.89
4.1
2.8
1.02
1.02
ratio
0.44
34
273
14
87
1.62
0.88
1.9
1.3
—
—
—
0
0
14
87
1.62
0.88
1.9
1.3
—
—
—
0
0
15
95
1.59
0.87
1.3
1.6
—
—
—
0
0
15
95
1.59
0.87
1.4
1.8
—
—
—
0
0
21
145
1.46
0.85
2.5
1.7
—
—
—
0
0
14
88
1.60
0.84
1.9
7.5
5.55
6.79
mmol/l
2.03
14
74
14
88
1.60
0.84
1.9
1.3
—
—
—
0
0
10
57
1.76
0.84
1.3
1.3
84.40
87.53
%
—
10
57
13
202
0.64
0.83
1.1
1.1
2.29
2.51
eliau/ml
—
8
86
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
8
48
1.67
0.79
1.1
1.0
15.84
38.75
iu/ml
—
8
48
23
165
1.40
0.78
2.6
2.5
—
—
—
0
0
16
107
1.50
0.76
1.0
1.1
1.56
1.39
g/l
0.93
16
98
135
1202
1.14
0.73
1.9
1.7
1.46
1.39
%
0.91
118
1088
5
25
2.01
0.72
1.6
1.2
—
—
—
0
0
5
25
2.01
0.72
1.6
1.2
—
—
—
0
0
732
7145
1.12
0.70
4.3
4.2
4.59
4.68
mmol/l
1.76
702
6838
735
7177
1.12
0.69
4.7
4.5
2.77
2.80
mmol/l
0.51
704
6848
10
61
1.65
0.68
1.2
1.7
11.74
10.03
umol/l
—
10
56
748
7316
1.12
0.67
22.9
16.2
333.48
333.47
g/l
0.00
748
7274
22
162
1.37
0.66
1.1
1.3
5.00
5.95
u/ml
0.11
13
65
26
197
1.33
0.66
2.1
1.6
—
—
—
0
0
14
202
0.69
0.66
1.9
2.2
9.28
11.03
mg/l
0.67
14
188
7
44
1.60
0.65
1.1
1.1
60.99
44.64
u/ml
—
7
44
32
251
1.28
0.65
3.4
1.9
—
—
—
0
0
35
435
0.80
0.63
1.9
1.9
—
—
—
0
0
38
307
1.25
0.62
1.7
1.6
—
48.57
—
0
6
0
20
0.00
0.60
0.0
3.2
—
—
—
0
0
35
431
0.80
0.59
1.1
1.1
1.52
1.53
g/l
0.13
35
431
244
2281
1.09
0.58
4.0
3.6
7.13
8.33
mmol/l
3.35
221
2027
15
106
1.42
0.58
1.9
2.4
189.99
96.31
ug/min
—
8
66
21
158
1.34
0.57
3.0
1.8
—
—
—
0
0
21
158
1.34
0.57
1.1
1.1
—
—
—
0
0
8
54
1.49
0.57
1.6
1.4
73.63
70.76
umol/l
—
8
54
60
697
0.85
0.56
1.1
1.1
—
—
—
0
0
6
37
1.63
0.55
2.3
1.7
—
—
—
0
0
6
37
1.63
0.55
2.3
1.7
—
—
—
0
0
6
37
1.63
0.55
2.3
1.7
—
—
—
0
0
6
37
1.63
0.55
2.3
1.7
—
—
—
0
0
33
267
1.24
0.54
2.5
2.1
6.47
3.67
iu/l
0.37
16
112
9
60
1.50
0.54
1.0
1.1
1676.89
1468.35
miu/ml
—
9
60
201
2158
0.91
0.54
2.5
2.4
—
—
—
0
0
72
629
1.16
0.54
2.5
2.4
11.33
12.26
nmol/l
0.41
65
590
314
2977
1.08
0.54
1.7
1.9
1.29
1.36
mmol/l
0.87
281
2632
9
62
1.46
0.53
1.6
1.4
—
—
—
0
0
6
39
1.54
0.53
2.2
1.3
—
—
—
0
0
185
1991
0.91
0.52
2.5
2.3
—
—
—
0
0
6
96
0.62
0.52
1.2
1.2
—
—
—
0
0
6
99
0.60
0.52
1.2
1.1
—
—
—
0
0
9
135
0.66
0.52
1.9
1.7
8.41
7.49
mmol/l
—
9
129
10
145
0.69
0.51
1.1
2.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
153
1.31
0.50
12.8
13.3
0.29
0.38
iu/ml
—
10
86
6
41
1.47
0.50
1.0
1.5
3.62
4.32
nmol/l
—
6
41
18
136
1.33
0.49
1.2
1.1
10.62
5.31
iu/ml
—
6
29
724
7105
1.09
0.48
4.2
4.1
1.44
1.46
mmol/l
0.99
691
6771
128
1395
0.90
0.47
2.5
2.2
—
—
—
0
0
24
299
0.80
0.47
1.0
1.1
10.40
7.73
u/ml
0.23
14
175
25
200
1.26
0.47
1.1
1.1
2.73
2.12
—
5
30
33
396
0.83
0.46
1.5
1.7
4.79
3.08
mg/l
0.58
24
266
52
599
0.86
0.46
1.3
1.3
—
—
—
0
0
107
1175
0.90
0.46
2.2
2.0
—
—
—
0
0
21
265
0.79
0.46
1.0
1.1
2.97
0.26
u/ml
—
9
111
11
77
1.43
0.45
2.6
2.5
0.17
0.10
nmol/l
0.53
11
58
35
294
1.20
0.43
1.7
1.6
235.55
204.08
u/ml
0.23
20
150
8
56
1.43
0.42
1.0
1.1
0.33
2.08
u/ml
—
8
56
6
93
0.64
0.42
1.2
1.2
—
—
—
0
0
6
94
0.64
0.42
1.2
1.2
—
—
—
0
0
6
95
0.63
0.42
1.2
1.1
—
—
—
0
0
184
1726
1.08
0.42
1.7
1.5
—
—
—
0
0
8
59
1.36
0.41
1.5
1.1
1.05
1.07
ratio
—
8
51
21
168
1.26
0.40
1.2
1.3
1.90
4.58
u/ml
—
10
62
29
242
1.20
0.39
3.4
1.8
—
—
—
0
0
15
115
1.31
0.39
3.1
4.2
1.23
2.48
ratio
—
7
66
37
429
0.86
0.37
1.9
1.6
0.16
0.29
mg/l
1.23
14
186
38
439
0.86
0.37
1.2
1.1
0.89
0.90
g/l
0.07
38
439
21
171
1.23
0.36
2.9
2.0
—
—
—
0
0
84
768
1.10
0.35
3.1
2.4
2510.24
6018.31
u/l
1.03
27
312
6
44
1.37
0.34
2.0
2.2
—
1401.00
—
0
5
54
482
1.13
0.34
2.7
2.6
68.16
77.30
ml/min/173m2
0.93
25
199
6
45
1.34
0.33
1.0
1.0
—
—
—
0
0
678
6673
1.06
0.32
3.6
3.6
1.22
1.22
mmol/l
0.09
640
6335
7
54
1.30
0.30
2.6
1.5
—
—
—
0
0
44
492
0.89
0.29
1.4
1.3
191.67
249.93
miu/ml
0.55
21
251
7
57
1.23
0.29
2.1
2.6
318.14
725.04
u/ml
—
7
57
9
121
0.74
0.27
1.4
1.6
—
—
—
0
0
22
187
1.18
0.26
1.8
1.9
—
—
—
0
0
13
104
1.25
0.26
1.3
1.3
—
266.67
—
0
6
39
348
1.13
0.26
1.5
1.5
—
—
—
0
0
5
74
0.67
0.26
1.2
1.6
0.58
0.49
e9/l
—
5
74
14
170
0.82
0.25
1.4
1.2
—
—
—
0
0
27
307
0.88
0.24
1.1
1.1
0.88
8.57
eliau/ml
—
5
54
24
274
0.87
0.22
1.0
1.1
6.51
8.01
u/ml
0.13
14
148
5
41
1.22
0.22
1.4
1.3
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
85.20
91.72
%
—
5
36
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
47
431
1.10
0.21
2.2
2.1
30.38
39.46
u/ml
0.41
47
414
8
105
0.76
0.21
1.5
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
679
6716
1.04
0.20
3.8
3.8
—
—
—
0
0
41
374
1.10
0.20
1.3
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
50
1.20
0.19
1.5
3.4
389.50
1323.48
mg
—
6
50
6
52
1.15
0.19
1.2
1.7
—
—
—
0
0
16
137
1.17
0.19
1.5
1.3
—
—
—
0
0
11
91
1.21
0.17
3.5
1.8
—
—
—
0
0
7
61
1.15
0.17
2.1
1.7
—
—
—
0
0
7
61
1.15
0.17
2.1
1.7
—
—
—
0
0
7
61
1.15
0.17
2.1
1.7
—
—
—
0
0
27
243
1.11
0.17
1.2
1.1
—
—
—
0
0
10
82
1.22
0.17
1.0
1.1
—
—
—
0
0
6
77
0.78
0.15
1.3
1.1
—
—
—
0
0
6
78
0.77
0.15
1.3
1.3
—
—
—
0
0
7
90
0.78
0.14
1.3
1.1
—
—
—
0
0
13
112
1.16
0.14
1.5
1.3
—
—
—
0
0
13
114
1.14
0.12
3.1
1.6
—
—
—
0
0
28
302
0.92
0.11
1.7
1.5
0.02
0.25
iu/ml
0.54
11
46
40
424
0.94
0.11
1.5
1.8
—
—
—
0
0
30
280
1.07
0.10
1.5
1.4
4.01
3.09
ug/l
0.60
25
258
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
44
1.14
0.10
1.0
1.3
120.40
107.82
%
—
5
44
26
279
0.93
0.09
1.6
1.4
—
—
—
0
0
15
135
1.11
0.09
3.0
3.5
34.45
28.87
mg/l
—
8
97
26
242
1.08
0.09
1.2
1.1
—
—
—
0
0
6
55
1.09
0.09
1.3
1.3
—
—
—
0
0
19
206
0.92
0.08
1.9
1.3
47.11
88.94
pmol/l
1.42
19
200
6
56
1.07
0.08
1.0
1.1
7.00
7.91
mm/h
—
6
56
59
613
0.96
0.08
2.5
2.6
0.52
0.70
ug/l
2.18
36
311
15
136
1.10
0.08
1.1
1.1
22.45
13.92
u/ml
—
6
50
6
57
1.05
0.08
3.0
3.5
17.17
69.28
u/ml
—
6
57
28
292
0.96
0.04
1.9
1.9
43.39
38.38
nmol/l
0.36
28
285
10
92
1.09
0.03
1.1
1.2
—
317.69
—
0
13
38
390
0.97
0.03
1.3
1.4
—
—
—
0
0
17
178
0.95
0.02
2.4
3.0
18.34
1223.06
u/ml
0.87
12
152
276
2750
1.01
0.01
2.1
1.8
—
—
—
0
0
42
426
0.99
0.00
2.7
4.3
2.91
18.70
ug/l
0.86
29
330
14
142
0.99
0.00
1.7
1.4
—
—
—
0
0
20
203
0.98
0.00
2.0
2.0
170.90
210.61
pmol/l
0.98
20
193
12
121
0.99
0.00
1.1
1.1
—
1.60
—
0
7
169
1689
1.00
0.00
4.1
4.2
4.91
19.05
mg/mmol
0.78
112
1105
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
5
52
0.96
0.00
1.2
1.3
3.93
5.10
u/ml
—
5
45
0
8
0.00
0.00
0.0
6.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
7
79
0.89
-0.00
1.3
1.3
—
—
—
0
0
5
58
0.86
-0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
8.60
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
5
57
0.88
-0.00
8.2
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
462.60
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
5
57
0.88
-0.00
8.2
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
24.50
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_NERVOUS_SYSTEM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_NERVOUS_SYSTEM | 2.691 [2.25, 3.23] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.139 |
During the follow-up period (1.1.1998 — 31.12.2019), 237 out of 4093 females with Q17_CONGEN_MALFO_NERVOUS_SYSTEM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_NERVOUS_SYSTEM | 3.066 [2.48, 3.79] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 242 out of 3664 males with Q17_CONGEN_MALFO_NERVOUS_SYSTEM died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_NERVOUS_SYSTEM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.247% | 0.659% |
| 5 | 1.631% | 3.359% |
| 10 | 3.77% | 7.849% |
| 15 | 7.188% | 14.821% |
| 20 | 12.271% | 23.606% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_NERVOUS_SYSTEM – Congenital malformations of the nervous system
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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