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Brain mixed glioma

DOID Endpoint Browser

C3_GLIOMIX

oligodendroglioma: A well-differentiated (WHO grade II), diffusely infiltrating neuroglial tumor, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). (Adapted from WHO)

Suggest a new description

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • HLP_C3_GLIOMIX
48

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C71
  • Cause of death: ICD-9 — 191
  • Cause of death: ICD-8 — 191
  • Cancer registry: Topography ICD-O-3 — C71
  • Cancer registry: Morphology ICD-O-3 — 9382
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

48

4. Check minimum number of events

None

48

5. Include endpoints

48

6. Filter based on genotype QC (FinnGen only)

44

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE
Control conditions
not HLP_C3_GLIOMIX

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 44 18 26
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 41.51 40.21 42.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
25
34
14.57
19.48
5.0
9.4
0.41
1.19
mmol/l
0.35
18
29
25
34
14.57
19.48
5.1
9.4
7.42
7.45
ph
1.26
16
14
20
8
41.89
16.43
1.1
1.1
—
—
—
0
0
29
98
6.12
8.77
2.7
3.2
98.10
89.97
%
1.34
29
98
15
17
12.36
8.33
6.5
12.3
24.13
25.71
mmol/l
0.50
15
17
29
116
4.92
6.74
3.1
1.6
—
—
—
0
0
13
20
8.53
6.08
7.3
13.1
1.00
1.62
%
1.34
13
20
13
20
8.53
6.08
7.3
13.1
0.75
0.75
%
0.01
13
20
39
216
5.72
6.04
17.5
9.0
2.97
3.98
e9/l
4.33
33
184
13
21
8.11
5.90
7.3
12.6
96.22
94.06
%
1.86
13
21
27
111
4.37
5.86
2.1
1.9
—
—
—
0
0
26
111
4.00
5.21
15.1
6.1
—
—
—
0
0
33
179
3.83
4.41
12.1
6.8
29.24
28.68
%
0.11
33
172
30
156
3.55
4.22
14.2
10.4
0.00
0.00
e9/l
0.48
24
124
35
209
3.64
3.80
12.1
7.4
0.15
0.20
e9/l
0.82
28
185
34
202
3.47
3.67
12.2
6.8
0.49
0.56
e9/l
1.46
28
176
34
204
3.41
3.57
12.2
6.7
0.02
0.04
e9/l
2.88
28
179
34
205
3.38
3.52
12.2
6.8
1.47
1.89
e9/l
3.37
28
181
13
47
3.44
3.12
6.2
7.1
107.46
103.15
mmol/l
2.73
13
47
5
5
10.96
3.05
1.8
1.2
—
—
—
0
0
10
32
3.69
2.63
8.8
10.8
—
—
—
0
0
8
182
0.33
2.59
1.8
2.9
—
—
—
0
0
22
123
2.48
2.34
13.1
6.6
—
—
—
0
0
8
25
3.64
2.21
2.5
8.3
8.80
8.93
mmol/l
—
8
25
0
48
0.00
1.82
0.0
1.5
—
—
—
0
0
31
218
2.24
1.79
7.5
4.1
6.46
6.64
mmol/l
0.20
31
198
0
43
0.00
1.62
0.0
1.8
—
—
—
0
0
6
135
0.36
1.62
3.5
2.4
43.83
56.69
u/l
—
6
127
31
380
0.46
1.58
2.4
4.3
5.53
5.78
mmol/l
0.43
26
359
5
15
3.60
1.56
4.0
4.6
—
—
—
0
0
18
257
0.51
1.33
3.1
3.8
—
—
—
0
0
5
18
2.98
1.32
2.2
3.9
36.82
36.84
°c
—
5
18
13
73
2.08
1.26
2.2
4.0
—
—
—
0
0
0
34
0.00
1.21
0.0
2.1
—
0.00
—
0
6
5
108
0.40
1.20
1.8
3.2
—
—
—
0
0
5
100
0.44
1.05
1.6
2.7
330.20
367.26
umol/l
—
5
93
0
26
0.00
0.81
0.0
1.1
—
1.45
—
0
26
0
26
0.00
0.81
0.0
1.1
—
0.95
—
0
26
0
27
0.00
0.80
0.0
1.1
—
0.78
—
0
5
0
27
0.00
0.80
0.0
2.7
—
132.67
—
0
27
15
103
1.67
0.77
4.7
3.2
7.40
7.40
ph
—
10
69
21
160
1.56
0.71
2.8
2.4
—
—
estimate
—
0
0
42
443
0.51
0.70
33.2
17.9
4.50
4.64
e12/l
0.95
42
433
42
443
0.51
0.70
33.4
18.0
137.55
140.57
g/l
0.70
42
437
42
443
0.51
0.70
33.2
18.0
5.62
6.56
e9/l
4.01
42
434
42
443
0.51
0.70
33.6
18.3
40.82
41.83
%
0.85
42
437
42
443
0.51
0.70
32.9
17.8
31.17
30.41
pg
1.95
42
438
42
442
0.53
0.68
33.2
17.9
92.50
90.82
fl
1.65
42
437
42
442
0.53
0.68
33.2
18.0
222.10
250.50
e9/l
2.69
42
434
5
28
1.88
0.68
1.0
1.1
—
—
—
0
0
0
20
0.00
0.62
0.0
1.2
—
—
—
0
0
0
19
0.00
0.62
0.0
1.6
—
0.00
—
0
6
39
416
0.63
0.61
14.5
9.5
—
—
—
0
0
0
22
0.00
0.61
0.0
2.3
—
0.55
—
0
22
0
23
0.00
0.60
0.0
1.1
—
—
—
0
0
7
46
1.61
0.51
1.9
1.9
437.29
447.33
nmol/l
—
7
39
7
102
0.63
0.46
1.3
1.3
—
—
—
0
0
0
15
0.00
0.42
0.0
2.1
—
19.87
—
0
15
0
18
0.00
0.41
0.0
1.7
—
323.08
—
0
12
0
18
0.00
0.41
0.0
3.1
—
—
—
0
0
5
78
0.60
0.39
2.8
3.2
—
—
—
0
0
11
142
0.71
0.38
1.5
2.0
99.60
94.74
pmol/l
—
5
69
7
98
0.66
0.35
1.1
1.9
—
—
—
0
0
7
56
1.29
0.31
2.0
1.9
3.26
4.93
umol/l
—
7
50
7
94
0.70
0.25
1.1
1.7
27.23
21.87
nmol/l
—
7
83
0
11
0.00
0.21
0.0
2.0
—
57.53
—
0
11
0
10
0.00
0.21
0.0
2.2
—
4.08
—
0
5
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
7269.83
—
0
6
0
13
0.00
0.21
0.0
1.0
—
1.04
—
0
8
0
13
0.00
0.21
0.0
1.9
—
9.62
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
25.53
—
0
14
42
401
1.44
0.18
20.2
12.8
3.92
3.95
mmol/l
0.42
42
394
42
401
1.44
0.18
21.2
12.7
139.71
139.72
mmol/l
0.00
42
396
5
44
1.15
0.10
2.4
3.4
2.11
2.24
g/l
—
5
39
5
45
1.12
0.10
1.2
2.3
—
—
—
0
0
7
79
0.87
0.08
1.6
2.2
21.64
4.77
e6/l
—
7
72
10
89
1.16
0.07
4.9
5.1
—
—
—
0
0
28
270
1.09
0.05
2.2
3.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
60.14
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
8.01
—
0
7
0
7
0.00
0.00
0.0
2.6
—
4.36
—
0
7
0
7
0.00
0.00
0.0
1.7
—
1.19
—
0
7
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
0.66
—
0
7
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
26.40
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
52
0.96
-0.00
3.2
2.5
3.82
4.02
e9/l
—
5
44
0
5
0.00
-0.00
0.0
1.2
—
222.80
—
0
5
0
6
0.00
-0.00
0.0
2.2
—
88.22
—
0
6
0
6
0.00
-0.00
0.0
3.5
—
8.78
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
34.74
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
7.37
—
0
6
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.8
—
60.00
—
0
6
0
5
0.00
-0.00
0.0
2.2
—
46.52
—
0
5
5
56
0.88
-0.00
1.2
2.8
462.80
548.02
mosm/kgh2o
—
5
48
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.5
—
1.46
—
0
8
0
6
0.00
-0.00
0.0
5.8
—
4.13
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
241.67
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
14.8
—
783.80
—
0
5
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.5
—
8.06
—
0
8
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_GLIOMIX – Brain mixed glioma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).