Cicatricial alopecia [scarring hair loss]

L12_HAIRLOSSSCAR

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L66
  • Cause of death: ICD-10 L66

2 out of 7 registries used, show all original rules.

314

4. Check minimum number of events

None

314

5. Include endpoints

355

6. Filter based on genotype QC (FinnGen only)

315

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Alopecia cicatrisans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1938 1201 729
Only index persons 1789 1155 634
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.02
Only index persons 0.04 0.04 0.02
Median age at first event (years)
Whole population 48.69 56.69 35.57
Only index persons 48.37 56.89 32.84

-FinnGen-

Key figures

All Female Male
Number of individuals 315 245 70
Unadjusted period prevalence (%) 0.07 0.09 0.03
Median age at first event (years) 56.10 59.62 43.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
323
Matched controls
3230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L66.1
ICD-10 Finland
Lichen planopilaris
+∞
157.6
138
*
D07AD01
ATC
clobetasol; topical
12.9
123.8
196
346
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.8
85.2
114
155
L66.9
ICD-10 Finland
Cicatricial alopecia, unspecified
+∞
80.7
74
*
P01BA02
ATC
hydroxychloroquine; oral
9.7
78.6
116
177
L66.8
ICD-10 Finland
Other cicatricial alopecia
+∞
50.3
47
*
70404
ICD-8 Finland
Diseases of hair and hair follicles, Folliculitis NUD
+∞
40.5
38
*
L66.2
ICD-10 Finland
Folliculitis decalvans
+∞
38.3
36
*
D07AC01
ATC
betamethasone; topical
4.2
35.2
199
895
L30.9
ICD-10 Finland
Dermatitis, unspecified
4.2
33.1
130
450
J01AA04
ATC
lymecycline; systemic
4.6
27.1
77
206
D07AC13
ATC
mometasone; topical
3.5
27.0
152
653
D07XC01
ATC
betamethasone; topical
4.5
26.4
78
215
D10BA01
ATC
isotretinoin; oral
6.7
24.0
41
69
XQ848
NOMESCO Finland
Dermatological photography
8.5
21.6
29
37
E0000UV, ,
ATC
3.1
21.5
190
1028
L66.0
ICD-10 Finland
Pseudopelade
+∞
21.1
20
*
L63.9
ICD-10 Finland
Alopecia areata, unspecified
117.7
20.8
22
*
L43.8
ICD-10 Finland
Other lichen planus
15.2
17.1
28
20
D07AB02
ATC
hydrocortisone butyrate; topical
2.7
17.0
136
676
H04.10
ICD-10 Finland
Dry eye syndrome
2.9
12.8
69
274
XQ845
NOMESCO Finland
Dermatoscopy
11.7
12.7
23
21
L66.4
ICD-10 Finland
Folliculitis ulerythematosa reticulata
+∞
12.6
12
*
L43.9
ICD-10 Finland
Lichen planus, unspecified
9.2
12.3
25
29
L71.8
ICD-10 Finland
Other rosacea
27.9
12.2
16
6
D05BB02
ATC
acitretin; oral
9.4
11.5
23
26
S01GX01
ATC
cromoglicic acid; ophthalmic
2.5
11.5
94
459
L93.0
ICD-10 Finland
Discoid lupus erythematosus
29.2
10.8
14
5
L64.9
ICD-10 Finland
Androgenic alopecia, unspecified
113.6
10.5
11
*
E000001, ,
ATC
2.4
10.2
82
395
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
8.8
9.7
20
24
L65.9
ICD-10 Finland
Nonscarring hair loss, unspecified
31.0
9.5
12
*
R06AX27
ATC
desloratadine; oral
2.2
9.4
115
657
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.7
8.9
29
84
L64.8
ICD-10 Finland
Other androgenic alopecia
+∞
8.4
8
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.6
8.4
54
233
S06
ICPC
Rash localized
3.4
8.0
29
90
D06BX01
ATC
metronidazole; topical
2.6
8.0
50
212
L71.9
ICD-10 Finland
Rosacea, unspecified
8.1
8.0
17
22
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
13.5
7.9
13
10
L04AX03
ATC
methotrexate; systemic
2.6
7.6
46
192
L66
ICD-10 Finland
Cicatricial alopecia [scarring hair loss]
+∞
7.3
7
*
L72.1
ICD-10 Finland
Trichilemmal cyst
3.6
7.0
23
67
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
6.6
163
1155
J01AA07
ATC
tetracycline; systemic
2.2
6.6
61
308
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.0
6.5
87
505
J04BA02
ATC
dapsone; oral
27.3
6.3
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
87
121
9.47
62.62
1.4
1.2
—
—
—
0
0
58
142
4.76
22.62
2.3
2.3
12.81
7.17
iu/ml
0.46
20
34
112
455
3.24
20.90
1.4
1.4
423.75
548.15
titre
0.54
32
108
44
112
4.39
16.17
1.3
1.3
2.50
7.53
u/ml
0.69
12
22
44
112
4.39
16.17
1.2
1.3
2.02
2.95
u/ml
—
8
14
231
1522
2.82
15.99
7.2
6.3
1.90
2.02
e9/l
0.67
205
1339
228
1498
2.77
15.77
7.3
6.2
0.04
0.04
e9/l
0.80
199
1277
232
1544
2.78
15.53
7.3
6.5
0.19
0.18
e9/l
0.64
206
1337
226
1489
2.72
15.36
7.3
6.3
0.55
0.55
e9/l
0.08
198
1269
36
93
4.23
12.92
1.1
1.2
38.86
48.68
u/ml
—
7
13
233
1657
2.46
11.89
8.9
10.2
3.63
3.89
e9/l
1.40
207
1441
206
1400
2.30
11.52
7.3
6.5
29.43
28.70
%
0.53
196
1327
203
1376
2.28
11.36
7.4
6.5
9.14
8.69
%
1.47
194
1291
78
354
2.59
11.06
1.8
1.5
—
—
—
0
0
201
1375
2.22
10.75
7.4
6.4
3.08
2.73
%
1.69
192
1285
200
1375
2.19
10.43
7.5
6.5
0.76
0.72
%
0.54
191
1282
124
745
2.08
8.82
1.5
1.3
0.79
1.27
u/ml
0.66
32
211
149
959
2.03
8.75
6.8
6.2
—
—
—
0
0
273
2250
2.38
7.54
7.5
8.1
74.05
77.92
u/l
1.19
259
2122
177
1332
1.73
5.46
11.5
11.2
0.00
0.00
e9/l
0.53
145
1076
182
1394
1.70
5.15
2.7
2.5
81.48
78.59
nmol/l
0.73
164
1258
165
1233
1.69
5.10
2.7
2.1
—
—
—
0
0
169
1275
1.68
5.01
4.0
4.5
36.24
36.13
g/l
0.08
151
1211
271
2344
1.97
4.84
5.4
4.6
14.33
14.78
pmol/l
2.65
249
2155
170
1295
1.66
4.78
2.2
2.1
101.08
98.27
pmol/l
0.33
67
637
97
647
1.71
4.46
1.6
1.5
2.71
2.41
g/l
0.48
62
383
64
383
1.84
4.24
2.7
2.2
123.60
124.60
ug/g
0.01
52
304
14
42
3.44
4.09
3.6
3.4
3.77
4.33
e9/l
0.47
14
42
40
210
2.03
3.89
1.2
1.2
123.88
153.26
u/ml
0.17
12
94
88
594
1.66
3.80
1.3
1.3
10.21
10.43
u/ml
0.01
35
235
98
686
1.62
3.65
6.0
5.0
—
—
—
0
0
51
304
1.80
3.41
1.7
1.6
—
—
—
0
0
102
734
1.57
3.35
2.5
2.1
2.46
3.02
mg/l
2.19
87
638
90
636
1.58
3.17
1.4
1.3
19.23
33.87
iu/ml
1.55
29
205
61
392
1.69
3.14
1.5
1.3
—
—
—
0
0
5
5
10.13
2.99
1.0
1.4
—
—
—
0
0
13
46
2.90
2.95
1.4
1.3
—
—
—
0
0
134
1062
1.45
2.65
2.5
3.3
2.36
2.36
mmol/l
0.17
119
960
57
378
1.62
2.60
2.9
3.3
6.78
4.79
e9/l
0.29
52
334
168
1395
1.43
2.55
3.9
2.9
151.56
104.45
ug/l
0.84
158
1296
120
943
1.43
2.45
2.6
2.5
57.99
59.82
u/l
0.14
108
873
291
2708
1.75
2.39
7.1
5.7
1.81
1.89
mu/l
0.68
272
2499
224
1972
1.44
2.38
3.2
3.2
39.51
46.59
u/l
1.37
209
1861
177
1499
1.40
2.32
6.8
7.1
1.22
1.22
mmol/l
0.01
153
1300
185
1579
1.40
2.31
4.8
6.6
10.71
10.45
umol/l
0.16
175
1512
9
29
3.16
2.24
1.4
1.6
21.89
22.92
ng/l
—
9
29
40
253
1.66
2.20
1.2
1.2
—
—
—
0
0
306
2906
2.01
2.13
19.9
17.7
3.94
3.95
mmol/l
0.12
301
2837
50
339
1.56
2.08
1.7
2.7
6.72
5.78
umol/l
0.21
42
302
14
63
2.28
2.04
3.5
3.1
53.71
58.49
%
1.04
14
63
153
1285
1.36
2.02
3.7
3.5
6.23
6.23
ph
0.01
84
702
79
594
1.44
2.00
1.6
1.7
491.42
452.94
pmol/l
0.47
64
487
81
612
1.43
2.00
2.7
2.6
2.44
2.45
mmol/l
0.47
74
550
7
21
3.38
1.97
1.0
1.0
—
—
—
0
0
161
1369
1.35
1.93
6.0
6.3
1.22
1.22
mmol/l
0.08
146
1259
185
1608
1.35
1.92
4.5
3.9
0.00
4.91
estimate
0.50
44
331
19
100
1.96
1.90
1.1
1.3
384.55
314.50
ug/g
0.66
11
56
6
17
3.58
1.84
1.8
1.2
82.67
74.69
ng/l
—
6
17
21
116
1.87
1.83
1.1
1.1
—
—
—
0
0
103
823
1.37
1.83
3.6
3.1
0.29
0.44
e6/l
0.55
76
585
229
2065
1.37
1.83
4.4
4.0
—
0.20
—
0
5
112
908
1.36
1.81
5.1
6.1
—
—
—
0
0
304
2902
1.81
1.75
20.0
17.7
139.86
139.83
mmol/l
0.09
297
2839
185
1623
1.33
1.73
4.5
3.9
0.00
0.00
estimate
-0.00
43
311
36
237
1.58
1.72
1.7
1.7
—
—
—
0
0
182
1596
1.32
1.69
4.5
3.8
0.00
0.00
estimate
-0.00
42
322
8
31
2.62
1.67
2.1
1.5
—
—
—
0
0
256
2367
1.39
1.63
22.9
19.7
331.69
331.44
g/l
0.18
256
2359
14
70
2.05
1.61
1.9
1.9
5415.14
687.47
u/l
—
7
28
10
43
2.37
1.60
1.2
1.1
4.40
1.97
eliau/ml
—
5
20
154
1328
1.31
1.58
2.1
2.0
1.29
1.37
mmol/l
0.74
133
1111
104
851
1.33
1.55
1.8
1.7
23.20
21.66
nmol/l
0.43
88
717
63
477
1.40
1.53
3.0
3.4
0.82
0.81
mmol/l
0.42
56
445
25
155
1.66
1.52
3.2
2.3
—
—
—
0
0
287
2718
1.50
1.50
7.0
6.4
38.42
38.93
mmol/mol
0.60
267
2555
297
2834
1.60
1.49
17.8
14.7
20.30
22.49
mg/l
0.58
252
2287
81
643
1.35
1.48
3.4
2.6
5.94
5.76
e6/l
0.05
72
594
9
38
2.41
1.47
1.6
1.4
—
—
nmol/l
—
0
0
221
2013
1.31
1.45
5.2
4.4
—
2.91
—
0
5
9
40
2.29
1.41
1.0
1.0
—
1.33
—
0
16
310
2996
1.86
1.40
15.6
12.1
30.20
24.99
u/l
1.01
305
2912
7
29
2.44
1.40
1.1
1.1
—
—
—
0
0
22
135
1.68
1.40
2.0
1.7
—
—
—
0
0
72
567
1.35
1.38
4.4
3.9
39.07
319.45
ng/l
2.69
58
435
33
227
1.51
1.33
3.9
3.9
—
—
—
0
0
37
261
1.47
1.32
5.0
5.2
0.29
0.51
%
—
7
80
90
738
1.30
1.31
4.7
4.0
—
0.14
—
0
7
52
394
1.38
1.27
8.0
7.5
105.04
104.23
mmol/l
0.88
52
394
138
1201
1.26
1.24
4.6
3.7
0.00
0.01
estimate
0.80
36
262
39
282
1.44
1.24
1.5
2.5
32.00
29.83
u/l
0.33
34
235
44
326
1.40
1.23
1.8
1.7
—
—
—
0
0
36
257
1.45
1.22
5.5
5.1
0.17
0.07
%
—
6
74
112
955
1.26
1.19
3.8
3.2
12.46
102.22
e6/l
0.71
85
716
14
79
1.81
1.19
1.1
1.2
—
116.00
—
0
10
69
553
1.32
1.18
3.1
2.8
559.46
516.26
mosm/kgh2o
0.81
59
486
28
192
1.50
1.16
1.8
2.3
—
—
—
0
0
85
703
1.28
1.15
1.8
1.6
0.78
1.19
mg/l
1.99
66
572
57
446
1.34
1.15
1.4
1.2
—
—
—
0
0
14
80
1.78
1.15
5.8
2.9
0.00
1.50
index
—
7
44
292
2801
1.44
1.14
5.8
5.2
5.79
5.88
mmol/l
0.66
276
2586
32
227
1.45
1.13
1.7
2.5
67.20
67.42
g/l
0.07
26
212
314
3066
1.87
1.11
28.6
23.1
4.48
4.46
e12/l
0.32
309
2995
56
439
1.33
1.11
2.7
2.2
2.30
2.35
g/l
0.30
50
405
110
944
1.25
1.09
3.8
3.5
7.40
7.40
ph
0.01
71
654
7
34
2.08
1.03
1.4
1.2
—
—
—
0
0
53
418
1.32
1.02
2.8
2.2
26.04
22.44
%
1.11
48
394
37
276
1.38
1.01
5.4
4.9
0.71
0.87
%
—
7
93
5
23
2.19
0.98
3.8
1.8
14.80
40.88
mg/l
—
5
16
10
54
1.88
0.97
1.5
3.2
—
—
—
0
0
9
51
1.79
0.95
1.6
1.7
—
—
—
0
0
57
459
1.29
0.95
2.8
2.9
4.07
3.07
e6/l
0.27
31
189
301
2917
1.47
0.95
15.5
13.2
—
—
—
0
0
88
751
1.24
0.91
2.6
2.7
335.37
331.81
umol/l
0.12
76
661
6
29
2.09
0.89
4.0
3.2
2.08
3.07
nmol/l
—
6
29
6
30
2.02
0.87
1.7
1.7
—
—
—
0
0
184
1694
1.20
0.87
5.0
5.2
6.56
6.58
mmol/l
0.04
175
1587
109
957
1.21
0.85
3.4
3.3
27.61
42.54
mg/l
0.59
68
578
114
1009
1.20
0.82
3.4
3.2
6.87
7.32
mmol/l
0.54
97
849
20
139
1.47
0.81
1.8
1.7
—
—
—
0
0
32
244
1.35
0.79
12.4
9.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.2
—
1.27
—
0
20
98
860
1.20
0.77
3.5
3.1
0.68
0.00
estimate
0.49
37
258
15
100
1.52
0.74
1.6
2.0
381.07
268.58
ug/l
0.22
15
94
107
951
1.19
0.73
3.4
2.9
—
—
—
0
0
49
402
1.26
0.72
2.1
2.0
—
—
—
0
0
72
832
0.83
0.71
1.4
1.4
—
—
—
0
0
295
2870
1.32
0.69
6.1
5.2
4.70
4.78
mmol/l
0.76
281
2676
36
287
1.29
0.67
2.4
2.1
0.00
0.05
estimate
—
10
59
144
1320
1.16
0.66
16.2
11.2
1.23
1.17
inr
0.74
123
1060
5
28
1.80
0.66
1.2
1.1
—
—
—
0
0
31
243
1.30
0.65
3.7
3.0
72.32
80.01
ng/l
0.40
25
213
109
979
1.17
0.65
4.0
4.0
6.09
8.12
mg/mmol
0.24
66
567
5
29
1.74
0.64
7.4
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
33
265
1.27
0.59
3.1
4.4
7.38
7.36
ph
0.60
23
184
27
211
1.31
0.59
3.1
2.5
9.97
18.51
au/ml
—
6
12
297
2902
1.29
0.57
6.7
6.0
2.75
2.78
mmol/l
0.29
282
2699
43
359
1.23
0.56
1.3
1.3
—
—
—
0
0
10
65
1.56
0.56
2.2
2.4
5.90
7.17
pmol/l
—
10
65
55
472
1.20
0.55
1.6
1.7
1021.23
1227.32
nmol/l
0.91
37
349
120
1100
1.14
0.54
4.6
3.9
55.05
58.17
e6/l
0.05
86
749
6
39
1.55
0.53
1.2
1.2
—
—
—
0
0
22
170
1.32
0.53
3.7
3.4
4.29
4.46
pmol/l
0.39
15
145
6
97
0.61
0.53
3.7
8.8
—
—
—
0
0
16
211
0.75
0.49
1.2
1.3
—
—
—
0
0
292
2856
1.23
0.48
5.7
5.1
1.51
1.54
mmol/l
0.63
277
2651
7
46
1.53
0.48
1.1
1.1
—
—
—
0
0
7
46
1.53
0.48
1.1
1.1
—
—
—
0
0
11
77
1.44
0.46
1.4
1.2
—
—
—
0
0
32
267
1.22
0.44
2.2
2.3
0.20
0.22
g/l
0.92
23
252
27
221
1.24
0.44
3.0
3.6
—
—
—
0
0
32
268
1.22
0.43
2.2
3.3
1.11
0.76
ug/l
0.37
18
175
8
57
1.41
0.42
1.0
1.4
—
—
—
0
0
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
129.81
—
0
16
0
17
0.00
0.41
0.0
2.8
—
44.70
—
0
10
0
19
0.00
0.39
0.0
1.2
—
32033.62
—
0
13
77
701
1.13
0.38
4.8
4.0
1.02
1.02
kg/l
0.22
46
447
5
37
1.36
0.37
8.8
1.3
—
—
—
0
0
38
329
1.18
0.37
9.1
10.1
7.43
7.42
ph
0.37
19
179
12
90
1.35
0.36
1.5
2.3
24.47
24.99
mmol/l
0.20
12
90
13
99
1.33
0.36
1.5
1.4
—
—
—
0
0
6
42
1.44
0.35
2.0
2.1
—
—
—
0
0
103
961
1.11
0.34
2.6
2.3
—
—
—
0
0
96
894
1.11
0.32
6.0
3.9
0.00
0.00
estimate
-0.00
40
309
6
47
1.28
0.32
1.0
1.1
—
—
—
0
0
278
2727
1.14
0.31
5.2
4.3
1.29
1.26
mmol/l
0.29
261
2517
33
287
1.17
0.31
1.3
1.5
—
—
—
0
0
7
55
1.28
0.30
1.3
1.8
—
—
—
0
0
7
57
1.23
0.29
2.4
1.7
0.68
0.89
nmol/l
—
7
43
8
64
1.26
0.27
4.1
1.9
5.25
4.65
mmol/24h
—
8
57
37
329
1.14
0.27
1.4
1.5
—
—
—
0
0
9
77
1.17
0.24
1.4
2.6
—
—
—
0
0
9
77
1.17
0.24
1.6
1.3
—
—
—
0
0
13
158
0.82
0.24
1.1
1.2
—
—
—
0
0
28
247
1.15
0.23
1.4
1.4
—
—
—
0
0
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
36
325
1.12
0.22
9.5
10.1
-0.67
0.95
mmol/l
0.88
31
278
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
2.3
—
53.70
—
0
10
0
10
0.00
0.21
0.0
1.2
—
26.60
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
122
1169
1.07
0.21
3.3
3.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
78.86
—
0
7
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.7
—
1.70
—
0
8
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
177.93
—
0
13
10
80
1.26
0.20
1.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
110.12
—
0
8
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
46
425
1.10
0.19
1.3
1.7
—
—
—
0
0
6
52
1.16
0.19
1.3
1.4
34.33
67.68
mmol/l
—
6
44
7
59
1.19
0.18
1.7
1.5
—
—
—
0
0
29
318
0.90
0.16
2.7
4.5
3.91
22.74
ug/l
0.80
21
265
25
226
1.12
0.15
2.5
2.9
70.36
72.71
e9/l
0.17
19
161
10
84
1.20
0.14
1.0
1.1
—
0.56
—
0
13
16
143
1.13
0.11
1.1
1.1
—
—
—
0
0
30
279
1.08
0.11
5.6
3.1
7.38
7.38
ph
0.05
18
159
29
271
1.08
0.10
1.4
1.4
—
—
—
0
0
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
6
55
1.09
0.09
1.2
1.6
—
—
—
0
0
5
65
0.77
0.08
8.2
1.3
—
—
—
0
0
8
76
1.05
0.07
2.1
3.7
—
—
—
0
0
26
245
1.07
0.07
3.3
3.1
1.24
1.23
mmol/l
0.19
20
213
7
85
0.82
0.07
1.0
1.1
—
—
—
0
0
30
285
1.06
0.07
5.8
3.0
5.71
5.79
kpa
0.22
30
279
10
89
1.13
0.07
1.5
1.4
—
—
—
0
0
137
1392
0.97
0.07
3.1
2.7
—
—
estimate
—
0
0
8
91
0.88
0.07
1.0
1.1
—
—
—
0
0
32
306
1.05
0.06
3.6
2.7
1.64
1.84
%
0.91
27
278
26
247
1.06
0.05
2.6
2.4
5.35
4.33
kpa
0.74
26
242
28
267
1.05
0.05
1.5
1.4
—
—
—
0
0
16
150
1.07
0.04
2.3
2.1
0.00
0.02
estimate
—
9
50
17
160
1.07
0.04
1.6
2.3
0.54
0.63
%
0.80
17
160
10
109
0.91
0.04
1.4
1.5
—
8.96
—
0
20
20
210
0.95
0.03
1.3
1.4
—
—
—
0
0
15
159
0.94
0.03
5.7
7.7
—
—
—
0
0
75
739
1.02
0.02
3.9
4.3
—
—
—
0
0
17
162
1.05
0.02
1.6
2.3
1.14
1.29
%
0.18
17
162
10
94
1.07
0.01
1.5
1.4
—
—
—
0
0
24
246
0.97
0.00
1.8
2.3
5.83
6.11
ph
1.15
12
164
49
496
0.99
0.00
2.1
1.9
—
—
—
0
0
11
112
0.98
0.00
1.3
1.3
—
—
—
0
0
12
118
1.02
0.00
4.3
3.3
—
—
—
0
0
112
1124
0.99
0.00
4.5
3.5
21.42
29.80
ng/l
0.76
76
781
10
95
1.05
0.00
1.5
1.4
—
—
—
0
0
10
95
1.05
0.00
1.5
1.3
—
—
—
0
0
10
95
1.05
0.00
1.5
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
62.00
—
0
6
0
6
0.00
0.00
0.0
2.3
—
20.88
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
5.18
—
0
6
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.8
—
5.04
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
1.2
2.0
—
—
—
0
0
9
95
0.95
-0.00
1.0
1.2
0.86
0.88
g/l
—
9
95
5
55
0.91
-0.00
2.0
2.3
24.60
30.54
umol/l
—
5
50
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
7
69
1.01
-0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
105.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
-0.00
1.0
1.2
1.54
1.58
g/l
—
9
90
5
55
0.91
-0.00
1.2
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
49
1.02
-0.00
4.0
4.2
16.40
77.73
u/ml
—
5
49

Mortality – FinRegistry

Association

Association between endpoint L12_HAIRLOSSSCAR and mortality.

Females

Parameter HR [95% CI] p-value
L12_HAIRLOSSSCAR 1.016 [0.78, 1.33] 0.91
Birth year 0.996 [0.99, 1.0] 0.377

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 867 females with L12_HAIRLOSSSCAR died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HAIRLOSSSCAR.

N-year risk Females Males
1 0.114% No data
5 0.624% No data
10 1.506% No data
15 3.054% No data
20 5.469% No data

Relationships between endpoints

Index endpoint: L12_HAIRLOSSSCAR – Cicatricial alopecia [scarring hair loss]

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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