No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
759 |
4. Check minimum number of eventsNone |
759 |
5. Include endpointsNone |
759 |
6. Filter based on genotype QC (FinnGen only) |
674 |
Control definitions (FinnGen only)
- Control exclude
- N14_FEMALEINFERT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF6
Similar endpoints
↥List of similar endpoints to
Ovarian hyperstimulation (induction)
based on the number of shared cases.
Similar with more cases:
- Complications associated with artificial fertilization
- Female infertility
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3890 | 3890 | - |
| Only index persons | 3869 | 3869 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.11 | - |
| Only index persons | 0.14 | 0.14 | - |
| Median age at first event (years) | |||
| Whole population | - | 31.54 | - |
| Only index persons | - | 31.54 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 674 | 674 | - |
| Unadjusted period prevalence (%) | 0.24 | 0.24 | - |
| Median age at first event (years) | 31.81 | 31.81 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 722
- Matched controls
- 7220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
180.2
307.7
197
15
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
329.5
307.7
378
24
TLW10
NOMESCO Finland
Transfer of fresh embryo
278.2
307.7
201
10
G03GA05
ATC
follitropin alfa; parenteral
83.4
307.7
382
96
N97.9
ICD-10 Finland
Female infertility, unspecified
269.8
307.7
442
42
H01CC01
ATC
ganirelix; parenteral
69.0
307.7
359
102
N98.1
ICD-10 Finland
Hyperstimulation of ovaries
+∞
307.7
721
*
TLW12
NOMESCO Finland
Insertion of frozen embryo
241.8
307.7
272
18
H01CA02
ATC
nafarelin; nasal
108.8
307.7
315
51
N97.4
ICD-10 Finland
Female infertility associated with male factors
68.8
307.7
221
46
G03GA02
ATC
human menopausal gonadotrophin; parenteral
57.6
307.7
253
67
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
92.1
307.7
299
55
G03GA06
ATC
follitropin beta; parenteral
85.2
307.7
315
65
G03GA01
ATC
chorionic gonadotrophin; parenteral
103.5
307.7
455
117
G03DA04
ATC
progesterone; systemic, rectal, vaginal
36.5
289.1
190
70
L02AE01
ATC
buserelin; implant, nasal, parenteral
83.8
234.2
125
18
N97.0
ICD-10 Finland
Female infertility associated with anovulation
1454.0
225.5
208
*
N97.8
ICD-10 Finland
Female infertility of other origin
312.3
190.7
186
8
L02BG04
ATC
letrozole; oral
15.1
190.7
189
166
TLW00
NOMESCO Finland
Insemination
444.6
175.6
169
5
TLW14
NOMESCO Finland
ICSI
61.4
137.5
77
14
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
48.4
125.7
74
17
L02AE02
ATC
leuprorelin; implant, parenteral
17.0
123.7
108
74
Z31.2
ICD-10 Finland
In vitrofertilization
154.8
112.9
117
9
Z31.3
ICD-10 Finland
Other assisted fertilization methods
67.7
112.7
62
10
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
5.4
110.7
455
1724
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
5.6
108.9
295
791
G03GB02
ATC
clomifene; oral
17.0
104.2
90
60
N97.1
ICD-10 Finland
Female infertility of tubal origin
1143.6
103.9
99
*
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
7.9
103.1
163
258
G03DB01
ATC
dydrogesterone; oral
4.7
83.2
274
837
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
4.6
75.5
532
2750
LA2HE
NOMESCO Finland
Repeated measurement of ovarian cyst
407.8
75.2
74
*
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
143.4
73.5
77
6
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
9.4
67.4
85
101
LA2JE
NOMESCO Finland
Follow-up of menstrual cycle with repeated measurement of ovarian cyst
711.0
67.1
65
*
H01CC02
ATC
cetrorelix; parenteral
31.2
66.6
44
15
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
6.4
60.4
109
194
N80.1
ICD-10 Finland
Endometriosis of ovary
6.8
59.8
101
168
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
+∞
56.0
53
*
B01AB05
ATC
enoxaparin; parenteral
3.4
52.5
275
1105
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.2
47.6
297
1310
JAH01
NOMESCO Finland
Laparoscopy
5.6
47.2
98
198
N80.9
ICD-10 Finland
Endometriosis, unspecified
6.0
46.8
88
162
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
3.1
46.2
292
1294
Z31.1
ICD-10 Finland
Artificial insemination
245.2
45.5
46
*
O00.1
ICD-10 Finland
Tubal pregnancy
6.7
41.5
69
112
L02AE03
ATC
goserelin; implant
13.7
41.1
39
30
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
4.4
39.1
108
276
W15
ICPC
Infertility/subfertility female
13.0
36.9
36
29
G03GA04
ATC
urofollitropin; parenteral
44.4
34.4
42
10
G03DC02
ATC
norethisterone; oral
4.4
34.4
95
242
Z31.6
ICD-10 Finland
General counselling and advice on procreation
9.8
33.9
40
43
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
11.8
32.9
34
30
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
30.9
363
2099
XLA10, ,
NOMESCO Finland
4.8
29.6
70
157
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
6.7
28.9
47
74
N97
ICD-10 Finland
Female infertility
36.7
27.7
35
10
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
9.7
25.4
30
32
O30.0
ICD-10 Finland
Twin pregnancy
5.5
24.9
50
97
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
4.2
24.7
70
181
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
4.5
24.5
63
151
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.4
24.4
214
1063
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
6.1
23.0
41
71
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.4
22.7
212
1078
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
5.9
22.3
41
73
LBF00
NOMESCO Finland
Perfusion of Fallopian tube
82.7
21.8
24
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.3
21.3
229
1231
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
20.9
385
2544
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
26.4
20.6
28
11
G03GA30
ATC
gonadotropins - combinations; systemic
23.2
20.5
29
13
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.2
20.3
215
1145
ULC02
NOMESCO Finland
Hysteroscopy
3.7
19.8
67
196
A10BA02
ATC
metformin; oral
2.5
19.2
140
632
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
3.1
19.0
85
297
Z31.4
ICD-10 Finland
Procreative investigation and testing
6.8
17.1
27
41
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
2.3
16.7
147
718
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
5.4
16.7
33
63
OAA11, ,
SPAT
2.3
16.5
141
680
O02.1
ICD-10 Finland
Missed abortion
2.4
16.1
122
558
N80
ICD-10 Finland
Endometriosis
5.0
15.8
34
70
N80.0
ICD-10 Finland
Endometriosis of uterus
3.8
15.3
48
133
G02CB03
ATC
cabergoline; oral
11.2
15.1
28
26
O20.0
ICD-10 Finland
Threatened abortion
3.2
14.5
59
194
OAA10, ,
SPAT
2.4
13.9
103
464
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.0
13.8
194
1127
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
3.5
13.6
48
144
W78
ICPC
Pregnancy
1.8
13.6
341
2385
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.1
13.5
58
197
LAC21
NOMESCO Finland
Laparoscopic destruction of lesion of ovary
5.2
13.5
28
56
ZXD05
NOMESCO Finland
Urgent procedure
1.8
13.4
293
1962
G03DC03
ATC
lynestrenol; oral
3.9
13.4
40
107
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.9
12.9
64
236
OAA12, ,
SPAT
2.3
12.2
99
464
G03DB08
ATC
dienogest; oral
5.6
12.2
23
42
J02AC01
ATC
fluconazole; systemic
1.7
12.0
412
3118
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.7
11.3
326
2337
SPAT1379
SPAT
Health check-up of pregnant person
1.7
10.6
244
1637
6289A
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD PRIM]
+∞
10.4
10
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
10.2
48
172
N80.5
ICD-10 Finland
Endometriosis of intestine
8.3
9.9
21
26
R2110
NOMESCO Finland
Giving the first information
2.3
9.8
80
375
TJA10
NOMESCO Finland
Laparocentesis
55.8
9.7
11
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.5
9.6
60
249
W29
ICPC
Pregnancy symptom/complaint other
2.4
9.5
70
314
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
5.2
9.4
19
37
N96
ICD-10 Finland
Habitual aborter
5.2
9.4
19
37
N98.9
ICD-10 Finland
Complication associated with artificial fertilization, unspecified
+∞
9.4
9
*
N97.2
ICD-10 Finland
Female infertility of uterine origin
+∞
9.4
9
*
G03GA09
ATC
corifollitropin alfa; parenteral
12.6
9.4
16
13
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.2
9.2
84
412
O82.0
ICD-10 Finland
Delivery by elective caesarean section
2.1
9.2
87
434
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
3.6
9.2
30
86
N84.0
ICD-10 Finland
Polyp of corpus uteri
2.4
9.1
62
268
B02AA02
ATC
tranexamic acid; systemic
1.8
9.1
161
995
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.8
212
1425
N83.1
ICD-10 Finland
Corpus luteum cyst
3.4
8.6
30
90
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
8.6
326
2455
1410
FHL
Laparoscopy
6.5
8.5
21
33
ZXD00
NOMESCO Finland
Emergency procedure
2.9
8.5
41
149
G03DA02
ATC
medroxyprogesterone; systemic
2.6
8.4
48
191
JAH00
NOMESCO Finland
Laparotomy
4.7
8.4
19
41
N98.8
ICD-10 Finland
Other complications associated with artificial fertilization
+∞
8.3
8
*
P01AB01
ATC
metronidazole; oral, rectal
1.6
8.3
330
2503
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.6
8.3
284
2080
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
2.8
8.1
40
148
1413
FHL
Laparoscopy and other therapeutic procedure
6.4
8.1
20
32
W12
ICPC
Contraception intrauterine
0.5
8.0
84
1491
B01AB04
ATC
dalteparin; parenteral
2.8
8.0
39
143
MA3AE
NOMESCO Finland
Combined first trimester screening
1.8
8.0
119
696
C05AA08
ATC
fluocortolone; rectal, topical
2.1
7.9
77
388
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
7.8
83
432
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
7.7
88
470
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.7
7.7
40
152
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
1.8
7.5
113
661
O60
ICD-10 Finland
Preterm labour and delivery
2.4
7.4
51
222
TLW20
NOMESCO Finland
Medical ovulation induction
+∞
7.3
7
*
N70.0
ICD-10 Finland
Acute salpingitis and oophoritis
6.3
7.3
18
29
M01AE02
ATC
naproxen; oral, rectal
1.5
7.2
442
3651
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
2.4
7.2
48
206
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.2
7.1
61
292
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
2.7
7.0
37
142
N83.0
ICD-10 Finland
Follicular cyst of ovary
3.1
7.0
28
92
N80.89
ICD-10 Finland
Endometriosis with other specified or multiple localization
5.9
6.9
18
31
LAD01
NOMESCO Finland
Laparoscopic partial excision of ovary
13.9
6.9
11
8
J01DB01
ATC
cefalexin; oral
1.8
6.9
615
5520
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.9
6.9
31
109
G03FB06
ATC
medroxyprogesterone and estrogen; systemic
3.9
6.8
20
53
LCA06
NOMESCO Finland
Biopsy of endometrium
1.8
6.8
116
705
A02BC01
ATC
omeprazole; systemic
1.6
6.7
175
1191
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.5
6.7
414
3403
UJF32
NOMESCO Finland
Coloscopy
1.8
6.6
115
704
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
0.4
6.5
26
675
R51.80
ICD-10 Finland
Headache
1.6
6.4
167
1135
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
1.8
6.4
108
654
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
3.2
6.3
24
76
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
6.3
121
759
ULB02
NOMESCO Finland
Falloposcopy
+∞
6.3
6
*
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.0
6.2
64
330
L82
ICD-10 Finland
Seborrhoeic keratosis
1.8
6.2
90
521
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
1.7
6.1
116
725
N02BE01
ATC
paracetamol; systemic, rectal
1.7
6.1
625
5682
A02BC05
ATC
esomeprazole; systemic
1.5
6.0
248
1864
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
129
228
6.67
72.45
2.1
1.3
1.74
0.36
nmol/l
5.25
124
186
128
284
5.26
55.84
1.2
1.3
9.07
13.19
u/l
2.66
112
226
326
1572
2.96
43.80
2.4
1.7
1.10
0.74
mg/l
3.74
276
1160
392
2128
2.84
41.52
4.1
4.2
34.70
37.46
g/l
16.53
381
2010
102
238
4.83
41.47
1.8
1.3
—
—
—
0
0
224
987
2.84
34.12
3.8
2.1
3693.11
7262.71
u/l
1.35
149
384
153
580
3.08
30.28
1.4
1.7
272.84
290.19
mu/l
0.42
139
522
190
944
2.37
21.27
1.3
1.3
11.13
22.92
iu/l
11.73
166
814
52
127
4.33
19.71
1.5
1.4
1.46
1.61
nmol/l
0.20
46
114
61
171
3.80
19.18
1.4
1.5
293.41
363.55
mu/l
1.19
56
136
486
3590
2.08
18.56
4.0
3.3
0.00
0.00
estimate
0.50
119
787
480
3540
2.06
18.27
3.9
3.2
0.00
0.00
estimate
0.80
119
802
484
3586
2.06
18.11
4.0
3.2
0.00
5.38
estimate
1.08
117
797
553
4384
2.12
16.15
4.6
4.0
3163.50
538.93
e6/l
0.63
12
44
247
1492
2.00
16.15
1.5
1.6
941.89
1047.95
mu/l
0.89
213
1235
437
3199
1.93
15.99
2.8
2.7
—
—
estimate
—
0
0
115
561
2.25
12.93
1.3
1.5
60.89
60.42
ug/l
0.04
115
561
283
1913
1.79
12.32
3.8
3.3
0.00
0.00
estimate
1.08
119
776
381
2818
1.75
12.02
3.7
3.0
0.05
0.02
estimate
0.28
106
685
640
5592
2.27
11.37
5.5
4.9
14.10
14.10
pmol/l
0.00
629
5368
165
983
1.88
10.61
1.5
1.4
—
—
—
0
0
121
652
2.03
10.43
1.7
1.8
—
—
—
0
0
697
6407
3.54
9.92
12.7
10.7
15.74
18.35
mg/l
2.07
618
5135
668
6017
2.47
9.79
9.8
9.2
138.83
139.41
mmol/l
9.61
663
5886
667
6028
2.40
9.27
9.8
9.2
3.87
3.88
mmol/l
0.12
661
5878
55
226
2.55
9.02
1.5
1.4
8.60
22.69
u/l
6.50
49
189
680
6215
2.62
8.92
6.5
5.7
1.53
1.68
mu/l
4.83
670
6036
130
757
1.87
8.85
1.6
1.6
—
—
—
0
0
226
1556
1.66
8.55
2.1
2.3
9.14
25.67
ng/l
2.46
64
526
300
2217
1.60
8.52
3.0
2.6
0.53
0.01
estimate
0.56
106
686
522
4422
1.65
8.18
4.3
3.4
52.59
55.62
ug/l
0.57
515
4260
227
1580
1.64
8.16
4.1
3.3
1.02
2.96
kg/l
0.80
156
1040
47
209
2.34
6.55
2.2
2.3
3.45
3.51
g/l
0.11
47
193
385
3139
1.49
6.33
3.7
4.0
5.91
6.09
mmol/l
1.16
344
2809
131
854
1.65
5.91
1.4
1.3
106.57
162.28
u/ml
0.95
52
358
204
1485
1.52
5.72
1.8
1.9
—
—
—
0
0
271
2118
1.45
5.25
1.3
1.3
0.48
1.75
u/ml
3.60
104
632
244
1871
1.46
5.22
3.2
2.9
—
—
—
0
0
336
2739
1.42
5.13
3.9
5.0
9.26
9.31
umol/l
0.04
319
2592
695
6616
2.35
4.79
9.7
8.8
24.34
22.99
u/l
0.91
689
6487
106
700
1.60
4.51
2.5
2.3
24.20
24.78
%
0.17
99
651
50
266
1.95
4.47
2.7
7.4
4.69
6.29
mmol/l
2.84
50
259
631
5857
1.61
4.40
8.9
8.4
97.99
97.29
ml/min/173m2
0.49
583
5251
118
804
1.56
4.39
2.4
2.1
2.62
2.50
g/l
1.38
111
746
214
1648
1.42
4.34
2.0
2.0
—
—
—
0
0
128
896
1.52
4.21
2.4
2.2
15.18
15.45
umol/l
0.16
120
836
7
7
10.08
4.01
1.0
1.0
3.05
1.40
nmol/l
—
7
7
156
1162
1.44
3.74
2.3
2.4
9.89
10.05
e6/l
0.03
143
1042
482
4299
1.36
3.73
6.1
6.6
65.60
69.94
u/l
2.99
465
4111
216
1706
1.38
3.69
2.8
2.8
93.61
94.06
e6/l
0.00
169
1257
37
191
1.99
3.64
2.1
2.6
-0.28
0.79
mmol/l
1.40
28
123
25
111
2.30
3.58
1.2
1.2
31.67
120.48
iu/ml
—
6
34
219
1744
1.37
3.54
2.3
2.4
67.30
55.61
u/l
0.36
211
1646
54
322
1.73
3.42
2.5
2.1
4.81
4.66
umol/l
0.07
41
231
12
32
3.80
3.40
1.3
1.6
—
—
—
0
0
70
449
1.62
3.37
5.7
4.0
—
—
—
0
0
21
89
2.40
3.34
1.3
1.9
0.93
1.92
ug/l
0.36
21
78
633
5962
1.50
3.22
4.5
4.2
—
—
—
0
0
161
1247
1.37
3.05
2.1
2.0
280.31
286.77
umol/l
0.56
154
1156
287
2425
1.30
3.00
1.5
1.6
—
—
—
0
0
15
58
2.62
2.89
1.5
1.4
—
—
—
0
0
15
58
2.62
2.89
1.5
1.4
—
—
—
0
0
107
780
1.44
2.87
1.5
1.5
—
—
—
0
0
62
403
1.59
2.86
1.2
1.3
—
—
—
0
0
65
429
1.57
2.81
2.4
2.5
—
—
—
0
0
107
784
1.43
2.79
1.6
1.5
1.05
1.14
ratio
0.56
68
493
107
786
1.42
2.75
1.6
1.5
1.00
0.94
ratio
0.77
68
495
107
786
1.42
2.75
1.6
1.5
1.26
1.20
ratio
0.24
69
497
209
1722
1.30
2.57
2.5
2.1
2.61
2.46
mg/l
0.53
187
1524
501
4604
1.29
2.52
4.5
3.8
8.04
8.26
mm/h
0.18
483
4407
99
730
1.41
2.50
2.0
2.2
395.31
384.98
nmol/l
0.19
88
688
29
159
1.86
2.47
1.2
1.3
7.18
3.81
u/ml
0.24
11
57
35
204
1.75
2.45
1.5
1.6
—
—
—
0
0
111
849
1.36
2.27
1.5
1.6
62.68
59.28
ug/l
0.35
94
714
33
194
1.73
2.26
1.2
1.2
—
—
—
0
0
32
187
1.74
2.24
5.3
8.5
23.03
23.42
mmol/l
0.35
32
177
179
1469
1.29
2.24
2.5
2.6
0.24
0.25
e6/l
0.03
135
1037
72
517
1.44
2.13
1.5
1.5
—
—
—
0
0
288
2517
1.24
2.10
1.9
1.8
—
—
—
0
0
62
434
1.47
2.09
4.1
5.6
105.26
105.44
mmol/l
0.11
62
434
11
44
2.52
2.02
1.1
1.3
—
—
—
0
0
32
194
1.68
1.99
1.2
1.2
—
—
—
0
0
129
1029
1.31
1.99
1.6
1.6
419.18
31163710.33
pmol/l
1.34
121
937
614
5856
1.32
1.96
14.4
12.8
13.15
13.25
%
1.87
609
5788
35
220
1.62
1.91
1.3
1.6
7.48
7.55
mmol/l
0.08
35
209
38
244
1.59
1.91
1.5
1.6
—
—
—
0
0
397
3612
1.22
1.91
6.6
8.6
3.92
3.99
e9/l
0.27
359
3187
18
93
1.96
1.86
1.2
1.2
—
—
—
0
0
175
1464
1.26
1.86
1.3
1.3
5.24
10.09
u/ml
1.08
72
643
263
2309
1.22
1.78
3.8
5.3
1.21
1.21
mmol/l
0.16
227
1999
27
162
1.69
1.77
1.5
3.0
0.64
0.64
%
0.00
27
162
46
315
1.49
1.76
1.2
1.3
—
—
—
0
0
47
324
1.48
1.74
1.4
1.9
—
—
—
0
0
145
1199
1.26
1.70
3.0
2.6
77.50
83.84
ug/g
0.21
128
936
27
167
1.64
1.60
1.6
3.1
1.24
1.40
%
0.29
27
167
7
26
2.71
1.58
1.4
1.5
—
—
—
0
0
76
974
0.75
1.54
1.5
1.6
1.19
1.33
%
1.28
71
875
5
15
3.35
1.52
2.6
2.1
21.60
42.17
ug/l
—
5
15
6
21
2.87
1.51
2.2
4.6
1.74
2.21
ratio
—
6
16
227
2009
1.19
1.36
3.4
4.7
1.21
1.21
mmol/l
0.01
218
1891
38
268
1.44
1.30
4.6
3.8
2.97
24.71
ug/l
0.57
27
183
86
691
1.28
1.29
1.4
1.8
—
—
—
0
0
568
5439
1.21
1.29
3.9
3.9
35.49
36.24
mmol/mol
1.83
558
5260
25
162
1.56
1.27
1.3
1.4
6.25
5.19
u/ml
0.13
12
68
24
154
1.58
1.27
1.4
2.0
—
—
—
0
0
17
100
1.72
1.24
1.1
1.3
—
—
—
0
0
45
331
1.38
1.24
1.5
1.9
—
—
—
0
0
5
19
2.64
1.22
1.0
1.2
—
—
—
0
0
9
168
0.53
1.20
5.9
7.2
23.56
23.88
mmol/l
—
9
162
201
1783
1.18
1.16
1.3
1.4
1.86
2.06
g/l
2.19
147
1230
37
267
1.41
1.15
1.0
1.1
1.01
0.75
u/ml
0.12
16
107
158
1374
1.19
1.15
3.1
3.2
97.73
98.35
%
0.14
153
1333
71
568
1.28
1.13
1.4
1.6
—
—
—
0
0
591
5701
1.20
1.12
3.3
3.4
5.35
5.49
mmol/l
3.13
571
5457
30
209
1.45
1.12
1.9
3.4
128.87
132.78
g/l
0.47
30
202
38
277
1.39
1.12
1.2
1.1
2.78
4.96
eliau/ml
—
6
50
16
96
1.68
1.11
1.1
1.2
15.74
14.01
u/ml
—
9
50
7
32
2.20
1.08
2.1
3.7
473.29
2400.03
mg
—
7
32
37
272
1.38
1.05
4.4
8.9
120.89
121.76
g/l
0.10
37
267
37
272
1.38
1.05
1.0
1.1
2.11
1.52
u/ml
0.23
21
123
16
98
1.65
1.04
1.9
1.6
—
—
—
0
0
10
53
1.90
1.01
1.2
1.2
2165.20
1388.55
miu/ml
—
10
53
42
318
1.34
1.00
1.1
1.1
2.90
2.99
u/ml
0.02
23
159
179
1593
1.16
0.99
1.4
1.4
24.34
20.45
iu/ml
0.26
48
473
38
285
1.35
0.97
1.0
1.1
3.30
4.64
u/ml
0.32
23
149
11
62
1.79
0.94
1.2
1.2
5.45
8.06
mm/h
1.27
11
62
156
1379
1.17
0.94
1.8
1.9
—
—
—
0
0
24
167
1.45
0.93
1.3
2.2
7.98
9.47
mg/l
0.74
24
160
10
55
1.83
0.92
1.2
1.7
1.45
1.63
mmol/l
—
10
55
17
111
1.54
0.88
3.4
3.2
33.32
20.95
mg/l
0.60
11
74
313
2917
1.13
0.87
2.6
2.4
76.46
72.11
nmol/l
2.05
302
2802
25
178
1.42
0.87
1.1
1.1
7.65
12.95
au/ml
0.70
13
54
201
1822
1.14
0.86
2.3
2.8
2.33
2.33
mmol/l
0.03
185
1707
24
170
1.43
0.86
4.6
8.2
95.81
94.34
%
1.60
24
170
47
373
1.28
0.83
1.7
2.2
83.82
85.03
ml/min/173m2
0.10
22
149
29
215
1.36
0.82
1.0
1.0
0.10
0.11
u/ml
—
7
58
33
250
1.34
0.81
1.1
1.1
4.60
4.73
—
5
43
43
340
1.28
0.79
4.3
7.7
4.74
4.93
kpa
0.83
43
323
43
340
1.28
0.79
4.3
7.7
13.29
14.28
kpa
0.67
43
323
0
26
0.00
0.78
0.0
1.4
—
5.58
—
0
21
7
123
0.56
0.78
1.3
1.1
—
—
—
0
0
18
123
1.48
0.78
1.2
1.6
6.57
7.15
mmol/l
0.70
18
123
25
183
1.38
0.77
1.4
1.4
—
—
—
0
0
73
617
1.20
0.76
1.7
1.6
1521.67
1094.88
nmol/l
2.56
64
492
57
470
1.23
0.75
1.4
1.6
—
—
—
0
0
7
38
1.85
0.73
2.1
1.9
95.00
103.67
nmol/24h
—
7
38
5
25
2.01
0.73
2.0
2.5
1.17
1.19
mmol/l
—
5
25
30
229
1.32
0.72
1.1
1.1
6.86
5.04
u/ml
0.24
15
92
237
2195
1.12
0.72
2.0
1.8
95.88
98.50
pmol/l
0.43
139
1305
5
26
1.93
0.70
1.0
1.0
—
—
—
0
0
5
26
1.93
0.70
2.0
2.5
107.80
106.00
mmol/l
—
5
26
9
142
0.63
0.70
1.2
1.5
—
—
—
0
0
24
178
1.36
0.69
1.3
1.7
13.00
30.18
e6/l
0.57
19
136
66
558
1.20
0.69
2.3
2.4
32.62
37.06
u/l
0.55
58
469
221
2383
0.90
0.69
1.7
1.7
1.40
1.29
mmol/l
0.45
201
2181
22
161
1.38
0.69
4.1
10.7
16.56
16.20
%
0.34
22
152
10
61
1.65
0.68
1.3
1.3
—
—
—
0
0
18
127
1.43
0.68
1.2
1.5
—
—
—
0
0
7
43
1.63
0.67
2.4
3.3
563.14
525.89
e6/l
—
7
38
44
358
1.24
0.67
3.1
2.1
—
—
—
0
0
12
78
1.55
0.66
1.2
1.1
—
—
—
0
0
12
79
1.53
0.63
2.6
1.2
—
—
nmol/l
—
0
0
41
334
1.24
0.62
4.4
7.8
0.03
0.58
mmol/l
0.27
26
244
0
20
0.00
0.60
0.0
2.6
—
—
—
0
0
0
20
0.00
0.60
0.0
2.2
—
2.46
—
0
9
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
22
166
1.34
0.59
1.6
2.6
41.19
63.04
ng/l
0.58
16
140
38
310
1.24
0.58
2.3
3.5
2.02
1.39
mmol/l
0.88
33
259
23
178
1.30
0.53
1.5
2.2
—
—
—
0
0
63
547
1.17
0.52
2.1
2.3
8.95
21.26
au/ml
2.67
11
80
77
681
1.15
0.50
1.7
2.4
91.72
405.92
ng/l
1.99
61
508
34
281
1.22
0.48
1.8
2.4
1.72
3.67
iu/l
—
9
135
33
272
1.22
0.48
1.3
1.3
3.63
17.67
u/ml
—
8
42
10
68
1.48
0.47
1.3
2.1
4.13
10.34
u/ml
—
10
68
8
117
0.68
0.46
1.1
1.3
—
—
—
0
0
19
148
1.29
0.44
1.1
1.1
117.16
116.52
%
0.03
19
134
9
130
0.69
0.43
1.2
1.5
—
—
—
0
0
5
31
1.62
0.43
1.2
1.1
—
—
—
0
0
23
185
1.25
0.42
1.4
1.4
—
—
—
0
0
8
57
1.41
0.42
1.1
1.3
8.83
9.76
umol/l
—
8
51
91
826
1.12
0.42
2.6
2.3
1.64
1.48
e6/l
0.06
45
389
0
15
0.00
0.41
0.0
1.7
—
41.07
—
0
15
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
21
168
1.26
0.40
1.2
1.0
6.20
2.40
eliau/ml
0.51
12
93
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
242
2309
1.07
0.37
2.2
2.3
—
—
—
0
0
10
72
1.39
0.37
1.5
1.8
—
—
—
0
0
16
127
1.27
0.33
1.4
1.2
—
17.60
—
0
7
70
636
1.11
0.33
1.6
2.4
6.27
5.28
umol/l
0.27
56
521
6
86
0.70
0.33
1.7
1.1
—
—
—
0
0
6
88
0.68
0.33
1.7
1.1
—
—
—
0
0
6
88
0.68
0.33
1.7
1.1
—
—
—
0
0
6
89
0.67
0.33
1.7
1.1
—
—
—
0
0
49
548
0.89
0.32
1.4
1.4
148.14
230.15
miu/ml
1.13
28
296
113
1055
1.08
0.31
4.0
4.2
9.23
11.85
mg/mmol
0.36
69
675
40
352
1.14
0.31
1.6
1.7
18.24
9.14
u/ml
0.43
13
98
7
100
0.70
0.30
2.0
1.5
0.56
0.56
g/l
—
7
92
101
941
1.09
0.30
1.6
1.6
3.57
3.34
mmol/l
1.09
62
618
29
250
1.17
0.30
1.1
1.1
8.15
4.53
u/ml
0.30
17
113
218
2090
1.06
0.29
2.1
2.2
—
—
—
0
0
8
107
0.74
0.29
1.1
3.5
0.47
1.03
nmol/l
—
8
93
8
108
0.74
0.29
1.1
2.5
—
—
—
0
0
51
464
1.11
0.25
1.4
1.6
—
—
—
0
0
20
170
1.18
0.24
1.8
1.6
6.95
6.57
mmol/l
0.28
20
154
9
76
1.19
0.24
1.0
1.1
—
—
—
0
0
49
446
1.11
0.24
1.1
1.1
1.59
1.58
g/l
0.03
49
446
6
83
0.72
0.24
1.0
1.2
—
—
—
0
0
6
83
0.72
0.24
1.0
1.2
—
—
—
0
0
6
85
0.70
0.24
1.7
1.1
—
—
—
0
0
63
582
1.09
0.24
1.1
1.1
—
—
—
0
0
20
171
1.17
0.23
1.3
1.3
216.09
221.55
u/ml
0.03
11
118
574
5672
1.06
0.23
3.1
3.0
1.14
1.13
mmol/l
0.12
552
5466
11
136
0.81
0.23
1.3
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
8
102
0.78
0.21
1.5
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
3.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
1072.17
—
0
12
20
173
1.16
0.21
2.0
2.2
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
127.44
167.58
iu/ml
—
5
43
0
13
0.00
0.21
0.0
2.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
2.08
—
0
13
0
13
0.00
0.21
0.0
1.7
—
1.19
—
0
13
10
123
0.81
0.20
1.1
1.3
—
—
—
0
0
6
49
1.23
0.20
1.2
1.3
—
—
—
0
0
6
50
1.20
0.19
1.0
1.4
—
—
—
0
0
49
453
1.09
0.19
1.1
1.1
0.83
0.85
g/l
0.38
49
453
7
63
1.11
0.17
1.1
1.1
123.14
114.83
pmol/l
—
7
63
41
379
1.09
0.16
2.6
2.3
10.83
7.40
iu/ml
0.28
12
90
21
188
1.12
0.15
1.2
1.3
—
42.40
—
0
7
54
509
1.07
0.14
1.5
1.5
—
—
—
0
0
10
84
1.19
0.14
1.0
1.1
—
—
—
0
0
91
873
1.05
0.14
1.8
2.0
2.40
2.39
mmol/l
0.46
80
770
8
98
0.81
0.13
1.1
1.3
—
—
—
0
0
8
99
0.81
0.13
1.4
1.6
—
—
—
0
0
9
106
0.85
0.13
1.1
1.1
—
—
—
0
0
80
768
1.05
0.12
2.8
2.5
5.25
4.41
e6/l
0.37
35
336
139
1355
1.03
0.10
1.8
1.5
22.26
20.04
nmol/l
1.15
131
1240
618
6150
1.03
0.09
3.7
3.7
2.84
2.84
mmol/l
0.04
598
5960
10
87
1.15
0.09
1.0
1.1
—
—
—
0
0
5
64
0.78
0.08
1.2
1.0
—
—
—
0
0
80
777
1.03
0.08
1.9
2.4
10.93
375.75
ng/l
1.59
28
309
11
98
1.12
0.07
1.4
1.9
44.10
162.63
ug/l
2.90
11
87
6
70
0.86
0.07
1.2
1.6
—
—
—
0
0
120
1175
1.03
0.07
1.7
1.7
3.36
3.22
ratio
0.58
83
836
17
157
1.08
0.07
1.1
1.1
—
—
—
0
0
9
86
1.05
0.07
1.1
1.1
191.56
198.31
mg/l
—
9
72
8
94
0.85
0.06
1.0
1.1
—
—
—
0
0
10
90
1.11
0.05
1.0
1.1
31.09
34.72
mg/l
—
10
72
38
366
1.04
0.05
1.3
1.4
—
—
—
0
0
49
504
0.97
0.04
3.6
2.9
31.11
31.97
%
0.27
44
411
34
328
1.04
0.04
1.6
1.7
—
—
—
0
0
17
180
0.94
0.04
2.0
2.1
13.18
13.14
%
0.04
17
180
11
102
1.08
0.03
1.7
1.8
5.90
5.41
pmol/l
0.11
11
102
611
6123
0.99
0.03
3.6
3.5
4.76
4.75
mmol/l
0.05
595
5950
491
4896
1.01
0.02
2.5
2.9
25.57
29.06
u/l
1.34
481
4747
10
93
1.08
0.02
1.0
1.1
—
—
—
0
0
612
6112
1.01
0.01
3.5
3.5
1.52
1.52
mmol/l
0.03
594
5920
16
166
0.96
0.00
1.3
1.3
377.25
366.61
ug/g
—
8
79
31
316
0.98
0.00
3.6
5.2
1.14
1.26
mmol/l
0.32
31
306
11
105
1.05
0.00
1.1
1.1
84.09
93.60
%
0.68
11
98
11
108
1.02
0.00
2.5
5.1
—
172.90
—
0
10
145
1455
1.00
0.00
3.2
3.3
7.77
8.10
mmol/l
0.40
137
1309
42
423
0.99
0.00
1.4
1.7
2.04
3.23
mg/l
2.10
29
288
20
201
0.99
0.00
1.4
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.3
—
1.25
—
0
8
0
8
0.00
0.00
0.0
2.0
—
5.98
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
67
0.89
-0.00
1.8
1.5
—
—
—
0
0
6
66
0.91
-0.00
1.8
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
1.2
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
5
53
0.94
-0.00
1.6
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
295.80
—
0
5
5
52
0.96
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
68
0.88
-0.00
1.8
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
95
0.95
-0.00
1.1
2.0
130.44
133.42
g/l
—
9
78
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
60.80
69.82
ug/l
—
5
50
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
3.60
—
0
6
6
68
0.88
-0.00
1.8
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
67
0.89
-0.00
1.8
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
68
0.88
-0.00
1.8
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_OVAR_HYPERSTIM and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have N14_OVAR_HYPERSTIM.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: N14_OVAR_HYPERSTIM – Ovarian hyperstimulation (induction)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data