Benign neoplasm: Ribs, sternum and clavicle

CD2_BENIGN_RIBS_STERNUM_CLAVICLE

bone neoplasm: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D16.7& Hospital discharge: ICD-9 — 2133 Hospital discharge: ICD-8 — 21302 Cause of death: ICD-10 — D16.7& Cause of death: ICD-9 — 2133 Cause of death: ICD-8 — 21302 2 out of 7 registries used, show all original rules.	92
4. Check minimum number of events None	92
5. Include endpoints None	92
6. Filter based on genotype QC (FinnGen only)	83

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D16
Name in latin: Neoplasma benignum costae, sterni sive claviculae

NAME	CD2_BENIGN_RIBS_STERNUM_CLAVICLE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D167
HD_ICD_9	2133
HD_ICD_8	21302
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D167
COD_ICD_9	2133
COD_ICD_8	21302
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Ribs, sternum and clavicle based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	837	393	438
Only index persons	695	347	348
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	34.51	37.27	32.09
Only index persons	30.43	34.20	26.66

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	83	42	41
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	41.10	44.26	37.87

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
86: Matched controls
860

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D16.7

ICD-10 Finland

Benign neoplasm: Ribs, sternum and clavicle

+∞

59.4

21302

ICD-8 Finland

Benign neoplasm of bone and cartilage, Costae, sterni, claviculae

+∞

27.6

2133A

ICD-9 Finland

Benign neoplasm of bone and articular cartilage, Ribs, sternum and clavicle

+∞

11.7

GAE06

NOMESCO Finland

Excision of lesion of chest wall

87.3

7.5

D48.0

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage

33.1

7.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

127

2.37

3.00

1.3

1.4

19.56

11.02

u/ml

—

(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum

7.49

2.58

1.0

1.1

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

3.90

2.43

2.0

1.2

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

2.55

2.29

1.5

1.3

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

3.56

2.24

1.9

1.4

—

3.88

—

(3026493) Urate [Moles/volume] in Serum or Plasma

201

1.94

2.17

1.9

3.2

302.70

333.29

umol/l

1.47

175

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

144

2.04

2.16

1.3

8.77

41.03

iu/ml

—

(36660697) Celiac disease serology panel - Serum

2.31

2.00

1.1

1.2

—

(3000991) Gas panel - Venous blood

2.34

1.94

7.8

12.5

—

(3042936) Bacteria identified in Isolate by Culture

111

2.04

1.89

1.2

2.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

128

1.97

1.83

1.3

1.6

—

(42870588) Differential panel, method unspecified - Blood

260

1.74

1.69

8.2

6.9

—

(40768800) Prostate Pathology biopsy report

3.72

1.64

1.0

1.1

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.18

1.58

8.0

11.7

1.38

1.30

mmol/l

0.14

(40768443) Skin Pathology biopsy report

2.57

1.58

1.1

1.3

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.73

1.55

1.4

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

564

1.85

1.55

5.2

4.7

15.26

14.89

pmol/l

0.68

518

(3026008) Bacteria identified in Urine by Culture

213

1.71

1.50

2.9

3.1

—

(3029937) Albumin [Presence] in Urine by Test strip

214

1.70

1.47

3.8

4.2

0.00

estimate

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

188

1.73

1.47

1.3

0.97

0.71

u/ml

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.92

1.44

1.6

1.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

433

1.66

1.43

9.6

11.6

3.53

4.19

e9/l

2.00

388

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

2.19

1.40

1.4

1.2

184.42

124.53

u/ml

—

(40768797) Stomach Pathology biopsy report

107

1.86

1.39

1.5

1.2

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

107

1.86

1.39

5.9

9.4

101.06

103.78

mmol/l

1.36

107

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

3.06

1.38

1.8

1.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

127

1.75

1.26

1.9

2.1

—

(3024928) Oxygen saturation in Venous blood

2.73

1.23

1.8

6.3

58.30

58.84

—

(3045424) Erythrocytes [Presence] in Urine

2.22

1.22

1.9

2.4

—

0.00

estimate

—

(3023420) DNA double strand Ab [Units/volume] in Serum

2.10

1.15

2.0

3.2

—

11.76

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.05

1.12

1.0

1.1

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.11

1.09

1.0

1.1

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.07

1.08

1.4

4.0

0.41

0.63

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.02

1.06

1.4

4.0

0.97

1.43

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

452

1.52

1.05

4.9

6.7

6.69

6.67

mmol/l

0.02

426

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.98

1.04

1.8

5.8

24.77

23.89

mmol/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

169

1.58

1.02

2.3

3.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

326

1.49

1.01

2.6

3.3

—

estimate

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.89

1.00

2.7

2.8

127.00

144.75

ng/l

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

102

1.70

0.99

5.6

5.1

35.55

33.68

0.28

(3019198) Lymphocytes [#/volume] in Blood

397

1.47

0.96

7.6

7.1

1.93

2.15

e9/l

0.38

362

(3012516) Albumin [Mass/volume] in Urine

246

1.48

0.91

3.1

3.4

14.64

57.77

mg/l

2.24

157

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.15

0.91

2.3

1.9

—

(3021601) Nitrite [Presence] in Urine by Test strip

400

1.45

0.90

3.7

4.0

0.00

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

410

1.45

0.90

3.8

4.0

0.00

estimate

—

(3044640) Blood type and Crossmatch panel - Blood

238

1.47

0.89

2.5

2.8

—

(3001604) Monocytes [#/volume] in Blood

392

1.44

0.87

7.7

7.0

0.58

e9/l

0.00

351

(3022145) Colonoscopy Study observation

1.64

0.85

1.5

1.3

—

(3035350) Ketones [Presence] in Urine by Test strip

403

1.43

0.85

3.7

4.0

0.00

estimate

—

(3006315) Basophils [#/volume] in Blood

394

1.43

0.83

7.9

7.0

0.04

e9/l

0.18

352

(3012544) pH of Venous blood

1.67

0.80

1.9

5.6

7.39

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

715

1.73

0.78

18.3

17.2

20.76

21.80

mg/l

0.09

578

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

2.24

0.77

1.4

2.3

—

(3020891) Body temperature

1.92

0.76

2.9

4.2

37.00

36.98

°c

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

322

1.39

0.73

4.1

5.3

35.68

35.97

g/l

0.13

304

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.90

0.69

2.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.64

0.67

1.0

1.3

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

1.64

0.67

13.3

13.5

25.06

24.63

mmol/l

—

(1761868) Lipid panel - Serum or Plasma

290

0.72

0.63

2.9

3.3

—

(3020682) Albumin/Creatinine [Ratio] in Urine

252

1.36

0.62

3.8

4.0

1.65

9.43

mg/mmol

2.71

160

(3032080) INR in Blood by Coagulation assay

358

1.34

0.62

14.1

14.2

1.19

1.24

inr

0.25

302

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

571

1.39

0.62

6.4

4.4

13.14

11.67

mm/h

0.34

522

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.59

0.61

10.1

10.4

24.84

24.88

mmol/l

—

(3003694) ABO and Rh group [Type] in Blood

203

0.68

0.61

1.4

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.60

0.0

1.6

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

669

1.47

0.59

7.0

5.8

1.85

1.87

mu/l

0.04

616

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.53

0.59

12.9

12.2

0.73

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.52

0.55

11.4

7.9

—

(3013512) EKG study

267

1.32

0.53

3.0

4.0

—

(3031040) Bacteria [#/volume] in Urine by Automated count

484

1.31

0.53

6.1

4.6

—

87.17

—

(3025941) Bacteria identified in Stool by Culture

1.54

0.52

1.7

1.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.45

0.49

1.8

2.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

273

1.27

0.44

4.4

3.4

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.47

0.44

12.9

11.9

1.84

1.73

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

701

1.40

0.43

5.0

5.5

4.77

4.59

mmol/l

0.69

643

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

680

1.36

0.42

6.8

39.80

39.86

mmol/mol

0.02

640

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

513

1.26

0.42

3.6

3.4

47.88

43.69

u/l

0.24

489

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.41

0.0

1.1

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.41

0.0

3.4

—

57.75

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.41

0.0

2.8

—

(3019977) pH of Arterial blood

1.40

0.40

9.6

14.9

7.44

7.42

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

1.45

0.40

1.4

1.24

1.61

g/l

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.41

0.39

1.0

1.9

55.00

46.29

u/l

—

(3023368) Bacteria identified in Blood by Culture

210

1.27

0.39

3.4

5.1

—

(40758558) Short blood count panel - Blood

241

0.78

0.38

4.9

7.0

—

(3000492) Spirometry study

0.64

0.37

1.4

—

(3015736) pH of Urine

307

1.24

0.37

3.9

3.7

6.31

6.25

0.09

176

(3022313) Gas panel - Capillary blood

1.50

0.37

5.5

3.2

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.37

0.36

1.2

1.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

330

1.21

0.33

2.5

2.2

95.96

97.06

pmol/l

0.05

167

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

697

1.31

0.33

4.9

5.4

1.54

1.46

mmol/l

0.64

638

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.32

0.31

1.0

2.1

—

(40761536) Microorganisms panel - Urine sediment

1.27

0.30

3.3

4.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.34

0.30

1.5

1.4

—

(40768804) Tissue Pathology biopsy report

294

1.20

0.29

2.2

2.0

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.32

0.29

1.6

2.6

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

711

1.29

0.28

5.5

6.2

2.77

2.67

mmol/l

0.35

657

(40761511) CBC panel - Blood by Automated count

722

1.30

0.28

18.8

14.9

—

(4035726) Immunohistochemistry procedure

0.66

0.27

1.8

1.3

—

(3019150) Specific gravity of Urine by Refractometry

171

1.22

0.26

4.2

4.4

1.02

kg/l

0.58

126

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

124

1.25

0.26

4.6

2.9

4.54

2.92

e6/l

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.33

0.23

1.0

2.1

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

136

1.22

0.22

4.3

2.8

7.65

0.67

e6/l

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

136

1.22

0.22

3.1

3.9

0.83

0.82

mmol/l

0.16

130

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

4.5

—

61.25

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.4

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.21

0.0

1.6

—

52.45

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.4

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

0.21

0.0

3.0

—

0.42

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(3014037) CD3+CD4+ (T4 helper) cells/cells in Blood

0.00

0.21

0.0

3.5

—

40.00

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

3.1

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.6

—

3.22

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.3

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

2.6

—

89.61

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

105.77

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.21

0.0

3.1

—

32.31

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

4.10

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

3.2

—

1.21

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

451

1.15

0.20

2.6

3.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.1

—

(3000012) Reticulocyte production index

0.00

0.20

0.0

2.9

—

0.94

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.20

0.0

1.1

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.20

0.0

4.0

—

20.19

—

(3021589) Normoblasts [#/volume] in Blood

328

0.87

0.20

12.8

13.7

0.00

e9/l

0.50

271

(3007164) IgA [Mass/volume] in Serum or Plasma

176

1.18

0.19

1.4

2.96

2.57

g/l

—

(3019060) Gas panel - Arterial blood

1.17

0.19

3.2

12.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.18

0.18

1.0

2.1

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.16

0.18

2.3

3.0

4.96

0.19

e6/l

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.16

0.17

1.4

2.9

0.22

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.20

0.13

1.3

1.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

126

0.85

0.12

1.5

1.8

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

163

1.13

0.12

3.3

2.9

0.50

0.79

ug/l

—

104

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

677

0.89

0.11

20.0

17.4

80.56

80.13

ml/min/173m2

0.07

639

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

314

1.08

0.08

1.9

2.2

1.33

mmol/l

0.01

267

(21494755) Public health laboratory ask at order entry panel

0.79

0.08

1.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.07

0.08

1.3

1.7

—

(3005719) IgG [Mass/volume] in Serum or Plasma

0.82

0.08

5.3

2.2

9.12

10.43

g/l

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

206

1.09

0.08

4.5

4.6

18.34

21.96

—

105

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

697

1.11

0.07

5.9

5.3

5.96

5.98

mmol/l

0.06

645

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.07

0.07

3.7

—

(3000494) Fungus identified in Specimen by Culture

1.07

0.07

1.3

1.9

—

(3002256) Pathology report gross observation

1.13

0.06

1.0

1.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

319

1.06

0.04

3.8

4.1

18.32

41.83

ng/l

1.30

227

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

108

0.92

0.03

1.5

1.6

—

(3018418) pH of Serum or Plasma

232

1.05

0.02

2.8

4.8

7.40

0.09

171

(40760892) CBC W Ordered Manual Differential panel - Blood

173

1.05

0.01

4.9

6.2

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

674

1.04

0.00

4.1

4.6

1.31

1.27

mmol/l

0.20

619

(3018095) Leukocytes [#/volume] in Urine

288

1.01

0.00

5.4

4.2

161.10

33.93

e6/l

0.78

204

(3030467) Casts [#/volume] in Urine by Automated count

227

1.02

0.00

4.7

3.3

0.37

0.31

e6/l

0.09

170

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

241

0.99

0.00

4.4

3.5

1147.20

1316.18

ng/l

0.10

201

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.7

—

(3007449) CD3+CD8+ (T8 suppressor) cells/cells in Blood

0.00

0.0

3.0

—

26.17

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.3

—

116.83

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

0.0

2.2

—

0.62

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

0.90

0.00

2.0

1.6

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

2.2

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.3

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.0

1.0

—

(3006245) CD3-CD19+ cells/cells in Blood

0.00

0.0

2.8

—

7.67

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.0

16.8

—

1243.17

—

(3009306) Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

4.15

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.0

19.2

—

1948.00

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.4

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

45.91

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.4

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

5.2

—

1.33

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

3.3

—

1.95

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.0

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.02

-0.00

1.5

1.7

0.81

1.25

g/l

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.7

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.2

—

115.32

—

(40761535) Cells panel - Urine sediment

1.02

-0.00

3.8

3.4

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

-0.00

0.0

11.6

—

(4198724) Urine methamphetamine measurement

0.00

-0.00

0.0

1.0

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

42.20

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

2.7

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

-0.00

0.0

2.4

—

3.86

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

3.39

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

2.1

—

15.96

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.4

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

1.4

—

2113.57

—

(3002582) Erythrocytes [#/volume] in Urine

260

1.00

-0.00

4.6

3.6

581.08

275.11

e6/l

0.21

199

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.6

—

65.80

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.1

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

309.20

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.91

-0.00

2.0

1.4

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

21.43

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

114.60

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.7

—

(3005033) Fetal Nuchal fold Thickness US

0.00

-0.00

0.0

1.4

—

1.34

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.6

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

7.24

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

14.40

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

7.44

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.02

-0.00

1.7

1.6

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.9

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

-0.00

0.0

1.0

—

6.19

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

2.6

—

11.08

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_RIBS_STERNUM_CLAVICLE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RIBS_STERNUM_CLAVICLE.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RIBS_STERNUM_CLAVICLE – Benign neoplasm: Ribs, sternum and clavicle

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Ribs, sternum and clavicle

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints