No definition available.
Anaphylactic shock due to adverse effect of correct drug or medication properly administered
ANAPH_SHOCK_ADVER_EFFECT_CORRE_DRUG_MEDICAM_PROPE_ADMINISTE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
513 |
4. Check minimum number of eventsNone |
513 |
5. Include endpointsNone |
513 |
6. Filter based on genotype QC (FinnGen only) |
455 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Anaphylactic shock due to adverse effect of correct drug or medication properly administered
based on the number of shared cases.
Similar with more cases:
- Other complications of surgical and medical care, not elsewhere classified
- Complications of surgical and medical care, not elsewhere classified
- Injury, poisoning and certain other consequences of external causes
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2507 | 1626 | 859 |
| Only index persons | 2350 | 1557 | 793 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.02 |
| Only index persons | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 51.79 | 51.85 | 51.61 |
| Only index persons | 51.56 | 51.44 | 51.80 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 455 | 326 | 129 |
| Unadjusted period prevalence (%) | 0.10 | 0.12 | 0.06 |
| Median age at first event (years) | 54.25 | 52.24 | 59.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 474
- Matched controls
- 4740
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
120.6
307.7
234
38
T88.6
ICD-10 Finland
Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
+∞
307.7
474
*
C01CA24
ATC
epinephrine; parenteral
15.1
171.9
187
196
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
56.6
171.7
99
22
XQ800
NOMESCO Finland
Prick test
11.5
123.2
153
188
T78.4
ICD-10 Finland
Allergy, unspecified
13.9
108.3
111
102
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
8.3
97.7
162
278
H02AB06
ATC
prednisolone; systemic
4.9
56.7
342
1643
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
14.2
39.5
37
28
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
12.0
38.5
40
36
J01FF01
ATC
clindamycin; systemic
3.4
36.9
204
856
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
8.4
36.4
50
66
J46
ICD-10 Finland
Status asthmaticus
9.4
34.5
43
50
L50.0
ICD-10 Finland
Allergic urticaria
8.0
31.9
45
61
L50.9
ICD-10 Finland
Urticaria, unspecified
6.4
30.8
54
93
N02AX02
ATC
tramadol; systemic, rectal
2.9
27.9
260
1412
WX892
NOMESCO Finland
Monitored bed care
4.8
27.2
66
153
R06AE07
ATC
cetirizine; oral
2.8
27.0
282
1616
J45.9
ICD-10 Finland
Asthma, unspecified
3.1
26.5
146
594
R03DC03
ATC
montelukast; oral
3.2
26.3
136
533
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
26.1
276
1582
X57
ICD-10 Finland
Unspecified privation
8.8
25.5
33
40
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
25.3
111
393
X59
ICD-10 Finland
Exposure to unspecified factor
3.1
24.9
134
535
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.8
24.6
87
267
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.3
24.5
112
406
A04AA01
ATC
ondansetron; systemic, rectal
4.0
23.8
75
212
Y59
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified vaccines and biological substances
25.4
22.5
31
13
A92
ICPC
Allergy/allergic reaction NOS
5.5
22.4
45
88
R06.0
ICD-10 Finland
Dyspnoea
2.7
22.2
175
850
R03AC02
ATC
salbutamol; inhalant
2.7
22.2
333
2200
R02
ICPC
Shortness of breath/dyspnoea
3.2
21.9
101
366
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.9
21.9
136
584
XQ820
NOMESCO Finland
Exposure to medicinal substance
39.2
21.0
26
7
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.4
20.6
85
287
J45
ICD-10 Finland
Asthma
3.3
20.2
86
296
X58
ICD-10 Finland
Exposure to other specified factors
2.9
20.1
113
457
R50.9
ICD-10 Finland
Fever, unspecified
3.0
19.7
108
431
J01MA02
ATC
ciprofloxacin; systemic
2.4
19.6
217
1221
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
19.3
104
410
J01MA12
ATC
levofloxacin; systemic
2.8
19.2
115
481
N03AX16
ATC
[U] pregabalin
2.6
19.0
144
678
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
18.9
146
694
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
18.9
173
891
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.6
18.8
136
625
G43.9
ICD-10 Finland
Migraine, unspecified
3.7
18.7
65
196
N02AA05
ATC
oxycodone; systemic
2.8
18.3
110
460
N03AX12
ATC
[U] gabapentin; oral
2.8
17.8
112
479
R55
ICD-10 Finland
Syncope and collapse
3.2
17.2
75
261
J45.1
ICD-10 Finland
Nonallergic asthma
3.7
17.2
59
176
X49
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
20.2
17.0
25
13
XQ801
NOMESCO Finland
Intracutantest
15.8
16.9
27
18
C03CA01
ATC
furosemide; systemic
2.4
16.8
149
750
A02BC02
ATC
pantoprazole; systemic
2.5
16.7
358
2615
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.2
16.2
70
242
R03BB04
ATC
tiotropium bromide; inhalant
3.3
16.1
65
215
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
16.1
95
391
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
15.5
125
600
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
15.4
89
362
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
15.4
222
1360
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
15.4
142
724
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.9
15.3
83
326
R11
ICD-10 Finland
Nausea and vomiting
3.0
15.1
72
263
L50.8
ICD-10 Finland
Other urticaria
6.8
15.1
24
37
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.7
15.1
97
417
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.9
15.1
77
293
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
15.0
53
161
R03BA05
ATC
fluticasone; inhalant
2.4
15.0
123
594
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
15.0
78
300
R51.80
ICD-10 Finland
Headache
2.5
14.8
117
555
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
14.7
130
649
R06AX27
ATC
desloratadine; oral
2.2
14.5
182
1050
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
14.4
160
878
S06.0
ICD-10 Finland
Concussion
2.8
14.3
80
319
Y88.0
ICD-10 Finland
Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use
43.9
14.2
17
*
H02AB07
ATC
prednisone; oral
2.7
14.1
86
359
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
14.1
91
391
R42
ICD-10 Finland
Dizziness and giddiness
2.3
14.0
129
654
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.9
14.0
42
114
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.2
13.0
55
187
JN3AD
NOMESCO Finland
Abdominal CT examination
2.6
12.8
82
350
H02AB04
ATC
methylprednisolone; systemic
2.5
12.6
89
398
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.7
12.6
77
321
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
12.6
121
621
J01FA06
ATC
roxithromycin; oral
2.0
12.6
215
1376
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
12.5
226
1473
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.1
12.5
27
56
UJF32
NOMESCO Finland
Coloscopy
2.2
12.5
136
734
A03FA01
ATC
metoclopramide; systemic, rectal
2.2
12.4
136
736
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.7
12.3
29
65
M54.8
ICD-10 Finland
Other dorsalgia
3.6
12.2
41
120
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.0
12.2
235
1565
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.7
12.1
39
111
JAH01
NOMESCO Finland
Laparoscopy
3.7
12.1
40
116
ZXD05
NOMESCO Finland
Urgent procedure
2.1
12.0
171
1022
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
11.8
50
170
R03AK08
ATC
formoterol and beclometasone; inhalant
3.7
11.8
39
113
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
11.5
11.6
21
19
M54.5
ICD-10 Finland
Low back pain
2.0
11.6
206
1326
N05BA04
ATC
oxazepam; oral
2.1
11.4
153
891
SPAT1229
SPAT
Assessment of need for aid
3.4
11.4
42
131
J45.8
ICD-10 Finland
Mixed asthma
4.5
11.4
28
65
XF600
NOMESCO Finland
Bloodpressure measurement
3.3
11.3
44
142
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.8
11.3
62
244
R06AE09
ATC
levocetirizine; oral
2.4
11.2
91
433
AA1AD
NOMESCO Finland
CT of head and brain
2.1
11.2
146
841
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
11.1
148
857
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
11.1
157
930
WX402
NOMESCO Finland
General anaesthesia
2.1
11.0
128
705
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.4
11.0
28
67
L04AB04
ATC
adalimumab; parenteral
5.3
10.9
22
43
J01FA09
ATC
clarithromycin; systemic
2.0
10.8
175
1086
J01AA02
ATC
doxycycline; systemic
2.2
10.8
385
3123
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.6
10.8
37
110
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
10.8
141
811
ZX120
NOMESCO Finland
Intravenous
2.7
10.8
60
238
T78.3
ICD-10 Finland
Angioneurotic oedema
9.5
10.6
21
23
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.0
10.6
23
48
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.8
10.6
24
52
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
10.5
63
259
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.0
10.5
49
176
XQ802
NOMESCO Finland
Epicutan test
3.7
10.5
34
97
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.3
10.5
27
65
SPAT1312
SPAT
General health counselling
2.0
10.5
166
1020
W84
ICD-10 Finland
Unspecified threat to breathing
33.3
10.4
13
*
Z3231
NOMESCO Finland
Registered nurse
2.0
10.3
146
861
R53
ICD-10 Finland
Malaise and fatigue
2.0
10.3
147
871
J01MA14
ATC
moxifloxacin; systemic
2.7
10.2
58
232
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.1
10.2
28
71
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
10.1
57
227
N02BE01
ATC
paracetamol; systemic, rectal
3.2
10.1
441
3833
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
10.1
65
277
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
10.0
56
223
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.9
9.9
47
171
R03AK03
ATC
[U] fenoterol and ipratropium bromide
3.6
9.8
33
97
A46
ICD-10 Finland
Erysipelas
2.4
9.7
73
335
M01AG02
ATC
tolfenamic acid; oral, rectal
2.2
9.7
96
495
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
11.7
9.6
17
15
R03AC03
ATC
terbutaline; inhalant
2.3
9.5
79
378
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
9.5
58
241
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
5.3
9.4
19
37
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.5
9.4
61
261
R96
ICPC
Asthma
2.5
9.3
61
262
N06AX21
ATC
duloxetine; oral
2.3
9.3
78
375
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
9.2
51
201
B01AB05
ATC
enoxaparin; parenteral
1.9
9.2
154
956
R03AK07
ATC
formoterol and budesonide; inhalant
2.0
9.2
121
692
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.1
9.2
40
138
R03DA04
ATC
theophylline; systemic, rectal
3.4
9.2
33
101
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
9.2
146
891
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.7
9.1
21
46
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
9.1
116
657
L17
ICPC
Foot/toe symptom/complaint
1.9
9.1
164
1044
R25.1
ICD-10 Finland
Tremor, unspecified
4.3
9.0
23
55
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.0
9.0
42
151
SPAT1263
SPAT
Sampling
1.8
9.0
205
1401
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
9.0
110
613
J01DB01
ATC
cefalexin; oral
2.3
8.9
407
3455
R60.0
ICD-10 Finland
Localized oedema
2.3
8.9
71
333
M54.3
ICD-10 Finland
Sciatica
3.1
8.9
39
135
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
12.9
8.9
15
12
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
8.9
64
287
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.7
8.9
48
187
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
8.9
90
467
C07AB07
ATC
bisoprolol; oral
1.8
8.9
215
1495
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
3.8
8.8
27
74
A04
ICPC
Weakness/tiredness general
2.1
8.8
89
461
R01AD58
ATC
fluticasone, combinations; nasal
1.9
8.8
145
895
I50.9
ICD-10 Finland
Heart failure, unspecified
2.5
8.7
59
257
N03AE01
ATC
clonazepam; systemic
3.1
8.7
36
121
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
8.6
151
948
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
8.6
149
933
G44.2
ICD-10 Finland
Tension-type headache
2.1
8.5
88
459
A28
ICPC
Limited function/disability NOS
2.2
8.5
81
409
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
8.5
54
228
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.5
8.5
57
247
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.2
8.5
77
381
WX872
NOMESCO Finland
Intensive care
3.6
8.5
28
81
N02BF01
ATC
gabapentin; oral
2.3
8.5
67
313
128
Kela drug reimbursment
Cancers of female genital organs
6.9
8.4
20
30
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
8.4
114
657
G47.3
ICD-10 Finland
Sleep apnoea
1.9
8.4
119
697
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.5
8.2
28
83
L01BA01
ATC
methotrexate; systemic
3.9
8.2
24
64
N06AX11
ATC
mirtazapine; oral
1.8
8.1
177
1185
R03BA02
ATC
budesonide; inhalant
2.0
8.1
102
573
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.4
8.0
20
47
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
8.0
188
1287
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.4
7.9
28
85
N06AX16
ATC
venlafaxine; oral
2.1
7.9
86
457
WVA20, ,
SPAT
3.5
7.9
27
80
M89.0
ICD-10 Finland
Algoneurodystrophy
11.1
7.8
14
13
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
7.8
161
1057
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.4
7.8
57
257
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
7.8
96
534
M13.9
ICD-10 Finland
Arthritis, unspecified
2.6
7.8
47
194
SPAT1254
SPAT
Administration of medicine
2.2
7.8
75
381
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.5
7.7
19
44
Z88.6
ICD-10 Finland
Personal history of allergy to analgesic agent
45.7
7.7
9
*
R01AD09
ATC
mometasone; nasal
1.7
7.7
239
1760
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.7
7.7
24
67
R03BA01
ATC
beclometasone; inhalant
2.1
7.7
77
397
SPAT1301
SPAT
No procedures
1.8
7.6
149
963
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
7.6
216
1552
T78.0
ICD-10 Finland
Anaphylactic shock due to adverse food reaction
25.5
7.6
10
*
M25.5
ICD-10 Finland
Pain in joint
1.7
7.6
181
1239
R06.2
ICD-10 Finland
Wheezing
3.2
7.6
30
98
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.3
7.5
29
93
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
7.5
69
343
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.5
7.5
50
216
KH1AD
NOMESCO Finland
CT of urinary organs
3.7
7.5
24
68
J01FA10
ATC
azithromycin; systemic
1.7
7.4
301
2376
N05CF01
ATC
zopiclone; oral
1.8
7.4
156
1029
H02AB02
ATC
dexamethasone; systemic
2.2
7.4
66
325
J33.0
ICD-10 Finland
Polyp of nasal cavity
3.9
7.3
21
55
XQ899
NOMESCO Finland
Other assessment of skin
9.6
7.3
14
15
WX882
NOMESCO Finland
High dependency care
6.0
7.3
19
33
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
7.3
276
2135
L04AX03
ATC
methotrexate; systemic
2.3
7.3
58
272
P29
ICPC
Psychological sympt/compl other
2.4
7.2
52
233
D10
ICPC
Vomiting
2.6
7.2
41
164
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.7
7.2
40
158
E0000UV, ,
ATC
1.7
7.2
206
1477
J01EA01
ATC
trimethoprim; systemic
1.8
7.2
136
868
P01AB01
ATC
metronidazole; oral, rectal
1.7
7.2
209
1506
J38.5
ICD-10 Finland
Laryngeal spasm
20.4
7.2
10
5
S18
ICPC
Laceration/cut
1.7
7.1
221
1617
M01AB05
ATC
diclofenac; systemic, rectal
1.7
7.1
316
2544
SPAT1260
SPAT
Consultation of another employee
2.0
7.1
87
482
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.1
7.1
70
358
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.0
7.1
32
113
WX704
NOMESCO Finland
Intubation
2.5
7.1
47
203
JN4AD
NOMESCO Finland
Body CT examination
2.2
7.1
59
282
R03BB01
ATC
ipratropium bromide; inhalant
3.4
7.1
25
76
R01AD12
ATC
fluticasone furoate; nasal
1.7
7.1
168
1144
N03AX11
ATC
topiramate; oral
3.5
7.1
24
71
L03
ICPC
Low back symptom/complaint
1.7
7.0
154
1024
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
7.0
45
191
A02BC03
ATC
lansoprazole; oral
1.8
7.0
134
857
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
7.0
45
192
R04.2
ICD-10 Finland
Haemoptysis
4.1
7.0
19
48
N05BA01
ATC
diazepam; systemic, rectal
2.1
7.0
71
368
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
3.6
6.9
23
67
R05FB02
ATC
cough suppressants and expectorants; systemic
1.7
6.9
179
1246
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
6.9
65
327
G43.3
ICD-10 Finland
Complicated migraine
4.2
6.9
18
44
SPAT1262
SPAT
Handing over of treatment supplies
2.0
6.8
77
414
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
6.8
77
414
D07AC01
ATC
betamethasone; topical
1.7
6.8
177
1232
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.1
6.8
29
99
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
6.8
158
1067
B01AF02
ATC
apixaban; oral
2.2
6.8
58
280
N20.1
ICD-10 Finland
Calculus of ureter
4.0
6.8
19
49
A02BC05
ATC
esomeprazole; systemic
1.7
6.7
194
1387
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.2
6.7
60
295
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.0
6.7
29
100
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
6.7
42
177
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.6
6.6
22
64
R06.5
ICD-10 Finland
Mouth breathing
2.3
6.6
50
229
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.9
6.6
31
112
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.1
6.6
27
90
C10AC01
ATC
colestyramine; oral
3.9
6.6
19
50
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
6.6
68
354
A03
ICPC
Fever
1.9
6.5
99
588
A02BC01
ATC
omeprazole; systemic
1.8
6.5
128
822
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
2.5
6.5
43
185
N01
ICPC
Headache
2.0
6.5
75
406
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
6.5
73
392
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
6.5
54
258
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
6.5
46
205
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.2
6.4
25
81
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
6.4
147
987
M79.6
ICD-10 Finland
Pain in limb
1.6
6.4
222
1659
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
6.4
170
1187
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.7
6.4
20
56
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.7
6.4
35
138
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
6.3
103
625
M03BX02
ATC
tizanidine; oral
1.7
6.3
300
2420
SPAT1255
SPAT
Intravenous administration of medicine
2.8
6.3
32
121
L28
ICPC
Limited function/disability (L)
1.9
6.3
87
502
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
6.3
67
353
GD1AD
NOMESCO Finland
Thorax CT examination
2.7
6.3
34
133
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.2
6.2
56
276
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
3.3
6.2
23
72
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
3.3
6.2
23
72
J01DA01
ATC
[U] cefalexin
1.6
6.2
295
2375
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
4.1
6.2
17
43
L04AX01
ATC
azathioprine; systemic
3.1
6.2
26
88
R10.0
ICD-10 Finland
Acute abdomen
3.5
6.2
21
62
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.6
6.2
37
152
S97
ICPC
Chronic ulcer skin
2.6
6.2
36
146
A10BA02
ATC
metformin; oral
1.8
6.2
121
776
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
6.2
51
243
LCD00
NOMESCO Finland
Hysterectomy
3.0
6.2
27
94
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.0
6.2
27
94
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
6.1
41
178
C56.71
ICD-10 Finland
Serous epithelial malignant tumor of the ovary
12.7
6.1
10
8
Z51.5
ICD-10 Finland
Palliative care
2.4
6.1
40
172
J01DC02
ATC
cefuroxime; systemic
2.6
6.1
34
135
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.7
6.1
153
1050
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
2.1
6.1
57
286
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.1
6.0
25
84
J01DA09
ATC
[U] cefadroxil
1.7
6.0
129
847
L01
ICPC
Neck symptom/complaint
1.9
6.0
91
539
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
5.7
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
292
1727
2.80
25.88
6.9
4.7
35.12
36.36
g/l
2.88
275
1644
368
2464
3.21
25.72
15.2
9.7
4.32
4.04
e9/l
1.53
340
2148
150
645
2.94
24.37
2.6
1.9
—
—
—
0
0
339
2209
2.88
24.15
8.8
6.3
9.37
10.66
umol/l
1.13
323
2114
109
413
3.13
21.94
9.1
7.7
1.07
0.96
mmol/l
0.12
91
350
236
1335
2.53
21.65
3.4
2.4
56.42
60.52
u/l
0.35
221
1244
115
460
2.98
20.97
2.4
1.8
—
—
—
0
0
281
1759
2.47
20.19
13.6
10.7
1.17
1.17
inr
0.02
252
1437
305
1997
2.48
19.60
11.9
6.6
1.20
1.21
mmol/l
1.88
270
1733
106
421
2.96
19.46
9.4
7.6
5.01
5.15
kpa
0.80
101
409
116
484
2.85
19.45
2.6
1.8
—
—
—
0
0
50
133
4.08
17.11
2.4
1.7
9.25
3.26
ug/l
0.34
41
120
335
2390
2.37
16.24
8.5
4.6
6.79
6.51
mmol/l
1.51
326
2235
104
449
2.69
16.08
2.9
2.1
363.92
380.22
nmol/l
0.24
97
427
25
38
6.89
15.90
1.2
1.2
0.21
0.35
u/ml
0.29
18
19
90
363
2.83
15.85
4.8
3.1
5.86
5.77
kpa
0.38
85
357
274
1817
2.20
15.61
10.4
5.8
1.20
1.21
mmol/l
2.49
259
1684
148
764
2.36
15.59
5.7
3.8
127.69
381.19
ng/l
1.04
105
558
135
678
2.39
15.07
5.6
3.0
0.81
0.82
mmol/l
0.33
129
644
177
1001
2.23
14.89
2.7
1.7
0.87
1.16
mg/l
1.15
144
785
400
3169
2.68
14.14
13.3
8.0
77.87
77.40
u/l
0.08
390
3010
84
350
2.70
13.80
5.0
3.1
2.23
1.89
mmol/l
0.31
72
300
186
1103
2.13
13.63
3.9
3.2
1478.24
964.95
ng/l
0.42
165
919
38
98
4.13
13.52
1.7
1.5
—
—
—
0
0
80
331
2.70
13.30
1.7
1.5
—
—
—
0
0
35
86
4.31
13.26
1.7
1.5
—
—
—
0
0
41
114
3.84
13.16
1.7
1.7
—
—
—
0
0
230
1508
2.02
12.56
5.2
3.6
27.00
76.21
ng/l
0.63
155
982
29
64
4.76
12.53
1.7
1.6
—
—
—
0
0
65
249
2.87
12.48
4.4
2.9
188.66
187.03
ng/l
0.01
59
221
39
112
3.70
11.96
1.7
1.6
—
—
—
0
0
227
1500
1.99
11.95
4.6
3.1
38.02
29.71
u/l
0.47
213
1422
352
2718
2.15
11.87
7.8
4.5
410.31
152.86
e6/l
0.58
13
43
175
1058
2.04
11.83
2.7
2.1
2.85
2.82
mg/l
0.06
148
913
198
1251
2.00
11.82
2.7
2.1
166.80
247.49
u/l
0.66
191
1193
69
282
2.69
11.70
2.0
1.5
—
—
—
0
0
55
202
2.95
11.37
4.6
3.3
2.45
1.96
mmol/l
0.48
47
150
31
81
4.02
10.83
1.7
1.5
—
—
—
0
0
36
108
3.53
10.35
1.3
1.2
583.07
136.06
e6/l
0.53
29
81
154
926
1.98
10.32
3.7
2.5
7.49
6.74
e6/l
0.19
149
842
28
71
4.13
10.18
1.6
1.8
—
—
—
0
0
35
106
3.49
9.92
1.2
1.1
9.30
9.96
e6/l
0.02
27
77
60
249
2.61
9.83
5.5
3.3
5.27
5.17
kpa
0.39
55
242
210
1420
1.86
9.73
3.6
3.3
2.33
2.36
mmol/l
2.35
191
1303
111
610
2.07
9.45
3.8
2.3
2.36
2.34
g/l
0.08
104
570
23
53
4.51
9.43
1.7
1.4
—
—
—
0
0
116
658
2.01
9.02
3.7
2.3
11.18
13.79
umol/l
4.28
110
617
166
1066
1.86
8.89
5.6
3.7
95.24
93.93
%
0.30
161
1044
23
56
4.27
8.81
1.7
1.4
—
—
—
0
0
198
1345
1.81
8.81
4.6
3.1
18.63
101.98
e6/l
1.01
165
1015
103
566
2.05
8.72
3.9
2.3
19.84
23.61
%
2.71
96
535
66
303
2.37
8.71
2.1
2.9
64.54
67.46
g/l
2.28
59
287
295
2269
1.79
8.49
5.9
3.7
16.97
3.39
estimate
0.36
71
479
266
1988
1.77
8.42
3.7
2.6
—
—
estimate
—
0
0
292
2244
1.78
8.37
5.9
3.7
0.00
0.00
estimate
0.50
69
468
135
828
1.88
8.25
1.5
1.3
5.04
10.66
u/ml
1.15
58
330
17
21
8.35
8.15
3.2
2.3
—
—
—
0
0
295
2286
1.77
8.10
5.9
3.8
0.00
0.01
estimate
0.80
69
449
67
323
2.25
7.88
2.7
2.4
8.31
16.18
au/ml
—
8
26
238
1750
1.72
7.75
2.3
2.0
92.67
97.86
pmol/l
0.96
140
898
257
1932
1.72
7.70
3.1
2.5
74.31
77.01
nmol/l
0.73
241
1765
372
3113
1.91
7.66
7.0
4.2
15.20
10.53
mm/h
6.16
357
2925
48
204
2.51
7.48
1.9
1.4
—
—
—
0
0
144
935
1.78
7.18
2.1
1.6
—
—
—
0
0
279
2171
1.69
7.14
4.1
3.0
138.24
101.89
ug/l
1.68
263
2045
140
904
1.78
7.10
1.5
1.3
16.82
30.63
iu/ml
2.69
40
280
125
783
1.81
7.01
1.9
1.7
412.21
9941092.43
pmol/l
0.50
108
674
451
4103
3.04
6.91
33.9
14.3
23.15
21.97
mg/l
0.37
423
3328
452
4118
3.10
6.88
35.6
16.2
3.94
3.94
mmol/l
0.00
447
4032
166
1147
1.69
6.52
2.0
1.6
18.96
21.08
nmol/l
1.06
148
990
55
268
2.19
6.29
3.2
2.4
5.55
6.31
ug/l
0.10
50
242
349
2944
1.70
6.03
4.4
3.2
53.84
42.76
u/l
1.45
338
2798
85
495
1.87
5.95
2.2
2.6
7.06
7.81
umol/l
0.11
79
437
146
995
1.68
5.95
6.2
3.7
1.02
1.02
kg/l
0.10
111
663
11
12
9.35
5.81
3.4
3.5
5.56
4.51
kpa
2.47
11
12
11
12
9.35
5.81
3.4
3.5
9.15
10.84
kpa
1.53
11
12
95
577
1.81
5.81
1.8
1.7
1209.95
1195.98
nmol/l
0.05
71
437
164
1158
1.64
5.79
4.3
2.9
0.41
0.40
e6/l
0.02
131
830
45
211
2.25
5.65
1.9
1.8
8.14
5.25
iu/ml
0.77
14
47
71
397
1.93
5.61
4.6
3.1
—
—
—
0
0
56
288
2.07
5.59
4.7
3.5
91.56
79.29
ng/l
0.41
50
261
186
1366
1.60
5.54
3.7
3.2
8.01
7.82
mmol/l
0.15
161
1165
28
106
2.74
5.51
2.8
1.5
—
—
—
0
0
29
112
2.69
5.49
1.4
1.2
—
—
—
0
0
25
89
2.91
5.49
1.7
1.3
—
—
—
0
0
16
36
4.56
5.10
2.3
1.8
89.42
90.52
%
0.35
16
36
35
154
2.37
5.09
1.2
1.3
13.09
2.61
u/ml
—
7
20
35
155
2.36
5.02
1.3
1.3
9.81
5.61
u/ml
—
7
33
45
224
2.11
4.90
2.3
1.7
—
—
—
0
0
14
29
4.94
4.84
1.2
1.0
—
—
—
0
0
219
1708
1.52
4.81
6.0
3.6
0.02
0.03
estimate
0.36
60
387
16
47
3.49
4.79
1.1
1.1
—
—
—
0
0
144
1037
1.56
4.50
3.9
2.7
336.20
329.00
umol/l
0.34
133
929
170
1270
1.53
4.49
4.8
3.1
0.00
0.01
estimate
0.99
57
375
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
82
2.76
4.48
4.4
2.6
0.34
0.41
iu/ml
0.33
14
46
11
20
5.60
4.31
2.1
1.5
—
—
—
0
0
23
90
2.63
4.28
5.3
4.3
119.17
614.89
iu/ml
—
6
9
13
29
4.58
4.27
1.5
1.2
0.69
0.50
ratio
—
8
17
13
29
4.58
4.27
1.9
1.4
—
—
—
0
0
11
21
5.34
4.16
2.2
1.5
—
—
—
0
0
11
21
5.34
4.16
2.1
1.6
—
—
—
0
0
20
74
2.78
4.14
1.2
1.3
—
—
—
0
0
22
87
2.60
4.02
2.2
1.4
16630.64
15583.28
e6/l
0.03
14
58
7
7
10.13
4.02
1.0
1.0
—
—
—
0
0
67
409
1.74
3.99
3.0
2.6
38.42
36.94
u/l
0.06
55
341
19
70
2.79
3.97
1.6
1.3
—
—
—
0
0
19
70
2.79
3.97
1.6
1.3
—
—
—
0
0
163
1234
1.49
3.95
7.0
3.8
0.00
0.01
estimate
0.74
69
447
14
43
3.32
3.93
1.1
1.2
—
—
—
0
0
30
139
2.24
3.92
2.7
2.0
—
—
—
0
0
166
1264
1.48
3.90
4.3
4.0
19.27
7.20
mg/mmol
1.21
110
770
20
77
2.67
3.85
2.0
1.3
—
—
—
0
0
15
49
3.13
3.84
1.1
1.1
—
—
—
0
0
374
3343
1.56
3.82
5.7
4.7
14.55
14.67
pmol/l
0.42
354
3101
7
8
8.86
3.78
1.0
1.0
106.00
95.75
%
—
7
8
8
12
6.76
3.68
1.6
3.0
0.64
0.62
mmol/l
—
8
12
112
794
1.54
3.67
3.1
2.6
2.44
2.45
mmol/l
0.19
97
716
51
295
1.82
3.64
5.5
3.3
1.23
1.23
mmol/l
0.01
46
254
11
25
4.48
3.64
1.5
5.0
6.97
7.89
mmol/l
0.47
11
25
64
396
1.71
3.64
2.4
2.0
—
—
—
0
0
455
4312
2.38
3.56
19.6
11.5
26.79
25.71
u/l
0.73
447
4209
327
2864
1.46
3.50
4.8
3.4
—
—
—
0
0
10
22
4.62
3.44
1.0
1.1
—
—
—
0
0
27
127
2.19
3.43
1.3
1.3
—
—
—
0
0
86
587
1.57
3.32
2.2
2.0
—
—
—
0
0
11
28
4.00
3.30
1.3
1.0
1.78
1.12
u/l
—
5
17
13
43
3.08
3.27
1.1
1.0
—
—
—
0
0
62
393
1.66
3.23
4.9
4.3
14.29
38.45
ug/l
0.56
46
321
93
651
1.53
3.21
3.7
2.8
4.35
2.67
e6/l
1.01
42
298
417
3870
1.64
3.13
6.9
5.7
1.67
1.84
mu/l
2.54
393
3633
12
35
3.49
3.12
1.8
2.1
—
—
—
0
0
18
74
2.49
3.08
1.2
1.1
5.62
15.95
au/ml
—
5
25
21
93
2.32
3.08
1.4
1.3
200.31
226.23
u/ml
0.28
13
51
8
17
4.77
2.93
1.0
1.3
—
—
—
0
0
7
13
5.45
2.88
7.7
6.8
—
—
—
0
0
26
130
2.06
2.86
3.8
2.2
190.77
177.92
%
0.40
26
125
17
71
2.45
2.83
4.5
2.5
7.52
7.38
pmol/l
0.02
17
71
27
138
2.01
2.81
1.8
1.6
—
0.05
—
0
21
12
39
3.13
2.79
1.2
1.1
—
—
—
0
0
5
6
8.40
2.75
3.6
1.3
37.20
33.83
umol/l
—
5
6
7
14
5.06
2.73
2.9
1.9
53.13
62.76
ug/l
—
7
14
26
133
2.01
2.71
2.9
1.8
—
—
—
0
0
36
206
1.81
2.70
1.9
1.4
0.29
0.27
mg/l
0.06
15
84
52
331
1.64
2.68
3.5
2.5
61.63
68.96
ml/min/173m2
0.63
27
141
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
24
3.80
2.68
1.0
1.2
—
—
—
0
0
89
642
1.48
2.65
2.4
2.2
—
—
—
0
0
23
114
2.07
2.61
2.4
2.5
—
—
—
0
0
8
20
4.05
2.58
4.0
2.4
0.38
0.85
index
—
8
20
143
1134
1.37
2.51
1.3
1.3
1.71
1.79
u/ml
0.03
37
314
18
84
2.19
2.38
1.7
1.4
—
—
—
0
0
7
17
4.16
2.37
1.1
1.0
—
—
—
0
0
50
326
1.60
2.36
2.2
1.9
—
—
—
0
0
404
3775
1.48
2.36
7.1
5.9
40.29
38.60
mmol/mol
2.34
385
3582
12
47
2.59
2.28
1.2
1.1
—
—
—
0
0
12
47
2.59
2.28
1.2
1.1
—
—
—
0
0
6
13
4.66
2.28
1.0
1.1
—
—
—
0
0
414
3894
1.50
2.26
5.4
4.8
6.01
5.84
mmol/l
1.48
387
3629
7
18
3.93
2.26
1.0
1.3
—
—
—
0
0
9
29
3.14
2.23
1.3
1.1
1.05
1.07
ratio
—
9
24
5
9
5.60
2.22
1.0
1.3
—
—
—
0
0
23
122
1.93
2.20
1.3
1.1
—
—
—
0
0
23
123
1.91
2.15
1.2
1.4
417.86
317.59
ug/g
0.91
14
70
93
706
1.39
2.10
3.8
2.7
0.70
0.89
e6/l
0.46
44
354
17
82
2.11
2.09
1.2
1.1
—
—
—
0
0
5
10
5.04
2.07
1.0
1.4
—
—
—
0
0
7
20
3.54
2.06
2.1
1.3
0.86
1.41
u/field
—
7
13
6
15
4.04
2.04
1.0
1.1
—
—
—
0
0
8
26
3.11
2.02
1.1
1.0
1882.50
1738.81
miu/ml
—
8
26
126
1014
1.33
1.97
3.1
2.1
—
—
—
0
0
12
51
2.39
1.96
1.2
1.1
—
—
—
0
0
8
27
3.00
1.94
1.3
1.1
—
—
—
0
0
11
45
2.48
1.94
1.2
1.2
—
—
—
0
0
13
58
2.28
1.92
1.2
1.2
—
—
—
0
0
7
22
3.21
1.88
1.7
1.1
332.71
743.15
u/l
—
7
22
16
79
2.06
1.87
1.6
1.0
0.42
1.21
u/ml
0.93
11
41
9
34
2.68
1.87
2.7
1.5
—
—
—
0
0
11
46
2.42
1.86
1.2
1.2
—
—
—
0
0
35
528
0.64
1.83
1.9
2.0
3.42
3.43
ratio
0.03
24
420
36
233
1.59
1.79
4.7
2.2
5341.22
5553.38
u/l
0.01
14
97
416
3952
1.43
1.79
28.3
13.8
83.20
85.31
ml/min/173m2
1.11
391
3636
29
178
1.67
1.77
1.4
1.3
235.75
285.30
miu/ml
0.33
20
82
6
18
3.36
1.75
1.7
1.3
—
—
—
0
0
6
18
3.36
1.75
1.7
1.3
—
—
—
0
0
9
36
2.53
1.74
1.1
1.1
—
—
—
0
0
9
36
2.53
1.74
1.1
1.1
114.11
109.42
pmol/l
—
9
36
8
30
2.69
1.73
4.0
2.3
16.50
12.75
index
—
8
20
14
68
2.09
1.72
2.4
1.9
—
—
—
0
0
15
75
2.03
1.71
1.6
1.2
2.17
4.07
u/ml
—
6
27
10
41
2.47
1.65
1.2
1.1
11.14
11.26
u/ml
—
5
22
10
42
2.41
1.62
1.3
1.1
—
—
—
0
0
21
121
1.77
1.61
1.6
1.3
—
—
—
0
0
11
50
2.23
1.58
1.9
1.5
—
—
—
0
0
25
153
1.67
1.56
3.8
3.2
8247.20
1658.27
u/ml
0.58
20
130
459
4470
1.85
1.56
46.5
22.1
4.44
4.50
e12/l
1.65
453
4382
6
21
2.88
1.51
1.0
1.0
—
—
—
0
0
21
124
1.73
1.49
1.3
1.1
—
—
—
0
0
9
37
2.46
1.48
2.0
1.5
—
—
—
0
0
9
37
2.46
1.48
1.3
1.4
—
—
—
0
0
9
37
2.46
1.48
1.1
1.1
—
—
—
0
0
13
66
2.00
1.44
1.2
1.2
—
—
—
0
0
12
59
2.06
1.44
1.3
1.4
—
—
—
0
0
43
306
1.45
1.42
1.5
1.4
17.11
26.66
iu/l
1.90
38
269
10
46
2.20
1.41
1.2
2.0
—
—
—
0
0
9
40
2.27
1.40
1.2
2.1
—
—
—
0
0
5
17
2.96
1.36
1.0
1.2
—
—
—
0
0
57
431
1.37
1.35
9.4
6.3
—
—
—
0
0
18
106
1.73
1.31
4.3
2.6
3.08
2.03
index
0.43
13
62
6
24
2.52
1.30
1.3
3.5
1.67
1.33
%
—
6
24
17
100
1.73
1.25
2.3
4.1
1.23
2.58
ratio
—
10
59
8
36
2.24
1.25
1.3
1.8
—
—
—
0
0
8
36
2.24
1.25
1.3
1.8
—
—
—
0
0
8
36
2.24
1.25
1.3
1.8
—
—
—
0
0
10
49
2.06
1.22
1.5
1.4
—
—
—
0
0
5
19
2.65
1.22
1.2
1.1
43.30
37.88
u/ml
—
5
19
70
557
1.30
1.19
1.9
1.6
1.47
1.44
%
0.13
54
500
27
182
1.51
1.18
1.3
1.5
—
—
—
0
0
8
39
2.07
1.15
5.0
3.9
—
—
—
0
0
8
39
2.07
1.15
1.9
3.3
7.22
3.34
nmol/l
—
8
39
11
58
1.92
1.13
1.4
1.2
—
—
—
0
0
25
168
1.52
1.12
1.2
1.6
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
21
2.40
1.09
1.6
2.3
209.80
117.76
%
—
5
21
37
489
0.74
1.00
2.3
3.0
0.56
0.72
ug/l
0.46
16
293
9
49
1.85
0.99
1.6
1.5
—
—
—
0
0
9
49
1.85
0.99
1.6
1.5
—
—
—
0
0
399
3841
1.25
0.97
4.4
4.1
1.45
1.25
mmol/l
5.54
370
3581
9
50
1.82
0.97
1.6
1.5
—
—
—
0
0
9
50
1.82
0.97
1.4
1.5
—
—
—
0
0
9
51
1.78
0.95
1.1
1.2
—
—
—
0
0
8
43
1.87
0.87
1.3
1.2
—
—
titre
—
0
0
32
240
1.36
0.85
1.3
1.4
—
—
—
0
0
22
158
1.41
0.76
1.4
1.3
—
—
—
0
0
5
24
2.09
0.74
1.0
1.7
107.40
103.37
%
—
5
24
5
24
2.09
0.74
1.2
1.2
1932.60
195.65
iu/ml
—
5
24
7
38
1.85
0.74
1.1
1.2
—
—
—
0
0
9
57
1.59
0.71
1.1
1.1
1.36
1.44
g/l
—
9
52
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
32
404
0.78
0.67
1.6
1.8
3.57
3.49
mmol/l
0.15
21
296
419
4088
1.22
0.66
5.7
5.5
2.79
2.79
mmol/l
0.02
390
3845
5
28
1.79
0.66
1.0
1.1
42.98
38.67
ng/l
—
5
18
5
28
1.79
0.66
1.0
1.0
418.20
295.11
ng/l
—
5
19
8
49
1.64
0.62
1.0
1.0
—
—
—
0
0
5
30
1.67
0.61
1.4
1.4
81.40
72.47
umol/l
—
5
30
6
40
1.51
0.51
1.2
1.3
50.33
51.63
u/l
—
6
35
188
1767
1.11
0.48
1.9
1.9
1.62
1.37
mmol/l
2.79
160
1517
96
871
1.13
0.46
1.6
1.5
—
—
—
0
0
7
50
1.41
0.45
7.1
3.6
183.86
52.36
u/ml
—
7
50
41
478
0.84
0.44
4.6
4.4
32.68
31.73
%
0.22
31
327
43
369
1.18
0.43
1.4
1.3
76.74
163.87
u/ml
2.55
16
155
5
31
1.62
0.43
1.6
3.3
1164.20
763.35
mg
—
5
31
17
131
1.31
0.42
5.7
2.4
1.74
1.33
mg/l
0.85
17
120
5
32
1.57
0.42
10.2
10.7
0.38
0.66
mmol/l
—
5
32
21
168
1.26
0.41
1.0
1.2
0.93
0.91
g/l
0.09
21
168
410
4029
1.13
0.38
5.2
4.8
1.44
1.50
mmol/l
2.07
382
3782
15
117
1.29
0.35
1.8
1.9
—
—
—
0
0
20
163
1.24
0.34
1.1
1.1
1.51
1.57
g/l
0.51
20
163
20
166
1.21
0.30
1.9
1.6
19.04
7.75
u/ml
—
5
35
9
72
1.25
0.25
1.3
1.4
3.67
3.08
ug/l
—
9
63
9
76
1.19
0.24
1.3
1.5
—
—
—
0
0
5
40
1.25
0.22
1.0
1.0
—
—
—
0
0
409
4043
1.08
0.22
5.3
4.9
4.76
4.74
mmol/l
0.14
383
3814
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
12
99
1.22
0.20
1.2
1.6
56.87
50.13
ug/l
0.25
12
99
19
166
1.15
0.18
1.7
1.9
—
—
—
0
0
13
151
0.86
0.16
1.5
1.5
—
—
—
0
0
85
811
1.06
0.16
4.2
4.9
1.52
2.35
ug/l
0.89
75
730
10
115
0.87
0.10
1.7
1.2
—
—
—
0
0
12
134
0.89
0.09
1.8
1.7
—
—
—
0
0
16
175
0.91
0.08
2.5
1.5
—
—
—
0
0
20
186
1.08
0.07
1.4
1.5
—
—
—
0
0
23
245
0.94
0.07
1.0
1.0
—
—
—
0
0
9
87
1.04
0.07
2.1
1.9
186.89
212.71
pmol/l
—
9
80
10
91
1.10
0.04
1.3
1.8
—
—
—
0
0
65
645
1.01
0.00
3.9
4.3
23.28
21.79
%
0.12
14
292
8
81
0.99
0.00
3.0
2.5
4.26
4.80
umol/l
—
8
64
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
40.60
—
0
5
7
72
0.97
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint ANAPH_SHOCK_ADVER_EFFECT_CORRE_DRUG_MEDICAM_PROPE_ADMINISTE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ANAPH_SHOCK_ADVER_EFFECT_CORRE_DRUG_MEDICAM_PROPE_ADMINISTE | 2.664 [2.09, 3.4] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.195 |
During the follow-up period (1.1.1998 — 31.12.2019), 249 out of 1378 females with ANAPH_SHOCK_ADVER_EFFECT_CORRE_DRUG_MEDICAM_PROPE_ADMINISTE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ANAPH_SHOCK_ADVER_EFFECT_CORRE_DRUG_MEDICAM_PROPE_ADMINISTE | 2.263 [1.67, 3.07] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.023 |
During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 723 males with ANAPH_SHOCK_ADVER_EFFECT_CORRE_DRUG_MEDICAM_PROPE_ADMINISTE died.
Mortality risk
Mortality risk for people of age
years, who have ANAPH_SHOCK_ADVER_EFFECT_CORRE_DRUG_MEDICAM_PROPE_ADMINISTE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.262% | 0.476% |
| 5 | 1.442% | 2.752% |
| 10 | 3.806% | 6.509% |
| 15 | 7.505% | 12.835% |
| 20 | 12.907% | 22.173% |
Relationships between endpoints
↥Index endpoint: ANAPH_SHOCK_ADVER_EFFECT_CORRE_DRUG_MEDICAM_PROPE_ADMINISTE – Anaphylactic shock due to adverse effect of correct drug or medication properly administered
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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