breast disease: A disease involving the breast.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
744 |
4. Check minimum number of eventsNone |
744 |
5. Include endpointsNone |
744 |
6. Filter based on genotype QC (FinnGen only) |
673 |
Control definitions (FinnGen only)
- Control exclude
- Q17_OTHER_CONGEN_MALFO
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q8
- Name in latin
- Malformationes congenitae mammae
Similar endpoints
↥List of similar endpoints to
Congenital malformations of breast
based on the number of shared cases.
Similar with more cases:
- Other congenital malformations
- Other congenital malformations, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4263 | 4107 | 135 |
| Only index persons | 4143 | 4029 | 114 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.00 |
| Only index persons | 0.14 | 0.15 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 29.72 | 30.19 | 14.84 |
| Only index persons | 29.83 | 30.23 | 15.89 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 673 | 662 | 11 |
| Unadjusted period prevalence (%) | 0.23 | 0.24 | 0.01 |
| Median age at first event (years) | 33.13 | 32.95 | 44.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 706
- Matched controls
- 7060
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q83.8
ICD-10 Finland
Other congenital malformations of breast
2346.6
307.7
354
*
Q83.1
ICD-10 Finland
Accessory breast
+∞
285.4
254
*
HAD40
NOMESCO Finland
Mastopexy
79.3
156.5
84
12
HAD99
NOMESCO Finland
Other plastic operation on breast
41.5
132.3
81
22
HAD10
NOMESCO Finland
Augmentation of breast using prosthesis
227.1
129.5
130
7
ZZF00
NOMESCO Finland
Graft of adipose tissue
32.8
120.6
79
27
HAC30
NOMESCO Finland
Excision of supernumerary mammary gland or mamilla
1120.7
101.8
97
*
Q83.9
ICD-10 Finland
Congenital malformation of breast, unspecified
+∞
81.9
77
*
HAE99
NOMESCO Finland
Other reconstruction of breast
23.3
70.8
52
24
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
4.9
53.2
134
322
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
6.3
52.2
95
170
Q83.3
ICD-10 Finland
Accessory nipple
+∞
49.6
47
*
N64.8
ICD-10 Finland
Other specified disorders of breast
13.5
37.7
36
28
HAD50
NOMESCO Finland
Removal of prosthetic implant from breast
50.7
36.1
43
9
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.9
35.6
85
193
ZXA10
NOMESCO Finland
Bilateral
3.2
32.6
161
605
N64.9
ICD-10 Finland
Disorder of breast, unspecified
9.2
32.2
40
46
N62
ICD-10 Finland
Hypertrophy of breast
4.7
31.6
79
186
HAD00
NOMESCO Finland
Augmentation mammoplasty
86.5
30.0
33
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
29.9
274
1412
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
5.7
27.5
53
99
HA1AA
NOMESCO Finland
X-ray mammography
3.7
27.0
94
282
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
25.3
195
915
T85.4
ICD-10 Finland
Mechanical complication of breast prosthesis and implant
93.5
24.8
27
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.2
20.6
271
1579
WX402
NOMESCO Finland
General anaesthesia
2.3
20.0
206
1085
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
19.9
195
1007
N64.2
ICD-10 Finland
Atrophy of breast
47.4
19.3
23
5
QBJ00
NOMESCO Finland
Liposuction in trunk
20.8
19.2
28
14
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
71.9
18.8
21
*
ZXA05
NOMESCO Finland
Left side
2.3
15.8
132
631
N64.5
ICD-10 Finland
Other signs and symptoms in breast
3.7
15.3
50
143
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
15.5
15.0
24
16
Q83.0
ICD-10 Finland
Congenital absence of breast with absent nipple
+∞
14.6
14
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
5.5
13.8
27
51
6114A
ICD-9 Finland
Other disorders of breast, Atrophy of breast
51.0
12.9
15
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.5
12.8
44
130
Q83
ICD-10 Finland
Congenital malformations of breast
+∞
12.5
12
*
M03AX01
ATC
botulinum toxin; parenteral
4.1
12.3
34
86
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
11.2
328
2365
N63
ICD-10 Finland
Unspecified lump in breast
2.3
10.9
88
412
9729
FHL
Other measure in this category
28.5
10.8
14
5
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
9.8
10.3
20
21
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
23.8
10.3
14
6
N02BE01
ATC
paracetamol; systemic, rectal
2.2
10.0
632
5597
HAB99
NOMESCO Finland
Other partial excision of mammary gland
4.3
9.7
25
60
ZXE00
NOMESCO Finland
One hour or less
1.7
9.7
283
2017
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
9.6
46
167
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
4.8
9.3
21
45
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
9.1
330
2471
ZXA00
NOMESCO Finland
Right side
1.9
9.0
124
708
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
12.7
8.9
15
12
P01AB01
ATC
metronidazole; oral, rectal
1.6
8.6
314
2345
R4110
NOMESCO Finland
Physiotherapy
1.7
8.1
166
1067
X21
ICPC
Breast sympt/compl female other
2.9
7.8
36
128
C05AA08
ATC
fluocortolone; rectal, topical
2.1
7.7
76
385
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
7.7
305
2308
J01DB01
ATC
cefalexin; oral
1.8
7.6
598
5310
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
7.5
281
2095
Z2221
NOMESCO Finland
Medical doctor
1.6
7.4
204
1412
J02AC01
ATC
fluconazole; systemic
1.5
7.3
353
2780
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
7.3
260
1914
J01AA02
ATC
doxycycline; systemic
1.6
7.2
493
4184
S59
ICPC
Skin, Other therap proced/minor surg NEC
3.6
7.2
23
65
QBJ99
NOMESCO Finland
Other aesthetic correction of skin of trunk
30.3
7.2
9
*
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
3.8
7.1
21
56
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
6.0
6.6
17
29
Z3226
NOMESCO Finland
Physiotherapist
1.8
6.6
110
663
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.5
6.6
22
64
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
6.6
61
302
WX702
NOMESCO Finland
Supraglottic ventilation device
2.4
6.5
44
190
N64.4
ICD-10 Finland
Mastodynia
2.3
6.5
48
216
HAD41
NOMESCO Finland
Transposition of areola
+∞
6.3
6
*
Q79.8
ICD-10 Finland
Other congenital malformations of musculoskeletal system
+∞
6.3
6
*
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.2
110
675
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
5.1
6.2
18
36
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
6.2
189
1335
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.1
201
1441
ZXD20
NOMESCO Finland
Day surgery
1.9
6.1
85
485
M03BC51
ATC
orphenadrine, combinations; systemic
1.6
6.1
183
1285
N05BA04
ATC
oxazepam; oral
1.6
6.1
189
1339
J01AA04
ATC
lymecycline; systemic
1.7
6.1
130
841
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
212
1347
1.82
11.21
2.9
3.2
100.01
97.58
%
0.92
206
1307
513
4303
1.70
8.90
6.9
6.5
70.37
71.97
u/l
0.60
490
4092
288
2128
1.60
8.14
3.7
4.1
37.80
37.44
g/l
0.61
267
2017
526
4546
1.62
7.03
4.3
3.8
8.60
8.92
mm/h
0.33
495
4301
391
3164
1.53
7.02
2.8
2.6
—
—
estimate
—
0
0
352
2798
1.51
6.79
4.9
4.9
9.35
9.45
umol/l
0.08
329
2634
230
1701
1.52
6.08
2.5
2.3
59.32
58.94
u/l
0.03
209
1585
167
1151
1.59
6.04
2.5
2.4
99.34
80.36
ug/g
0.51
130
902
303
2379
1.48
5.96
5.4
5.2
1.22
1.22
mmol/l
0.37
271
2040
122
808
1.62
5.15
1.5
1.4
20.41
23.12
iu/l
0.45
100
695
616
5664
1.69
5.12
15.8
13.3
13.23
13.26
%
0.35
611
5602
53
281
1.96
4.78
1.7
1.4
0.81
0.42
nmol/l
0.43
40
239
665
6275
2.03
4.77
12.6
10.8
18.55
17.99
mg/l
0.18
538
5020
638
5949
1.75
4.68
11.2
10.2
3.88
3.89
mmol/l
0.41
626
5791
261
2069
1.41
4.56
4.8
4.7
1.22
1.22
mmol/l
0.79
243
1916
348
2900
1.39
4.53
2.7
2.4
72.90
73.69
nmol/l
0.22
323
2733
595
5464
1.57
4.50
5.0
4.9
14.17
14.25
pmol/l
0.37
562
5150
636
5939
1.71
4.46
11.2
10.1
139.47
139.53
mmol/l
0.39
626
5799
412
3562
1.38
4.14
8.1
8.0
3.80
3.96
e9/l
0.94
360
3141
269
2179
1.38
4.02
1.7
1.6
—
—
—
0
0
594
5488
1.52
4.00
4.1
4.1
—
—
—
0
0
60
358
1.74
3.77
1.5
1.4
10.11
10.21
u/l
0.02
43
295
514
4640
1.40
3.76
3.2
2.9
32.29
30.92
u/l
0.26
492
4479
22
91
2.46
3.67
2.7
2.2
8.45
6.88
pmol/l
0.38
22
91
50
291
1.77
3.44
1.8
1.6
—
—
—
0
0
169
1300
1.39
3.37
2.2
2.0
—
—
—
0
0
402
3539
1.32
3.19
3.6
3.4
0.01
0.00
estimate
0.42
83
780
272
2273
1.32
3.13
1.8
1.8
100.67
97.34
pmol/l
0.71
141
1265
671
6448
1.82
3.06
13.5
11.9
65.26
65.43
umol/l
0.11
662
6377
242
1997
1.32
3.03
2.6
2.3
—
—
—
0
0
186
1479
1.35
2.99
3.0
2.6
0.17
0.31
e6/l
0.66
135
1029
48
289
1.71
2.96
1.7
1.6
11.74
9.23
u/ml
0.19
14
73
251
2087
1.31
2.96
1.4
1.4
0.95
1.98
u/ml
1.19
70
584
98
702
1.46
2.89
2.2
2.3
24.78
23.74
%
0.31
92
644
403
3589
1.29
2.75
3.8
3.4
0.00
0.01
estimate
1.08
81
763
701
6893
3.40
2.72
20.5
17.1
269.17
268.03
e9/l
0.20
692
6809
611
5780
1.42
2.64
10.1
9.1
96.14
95.57
ml/min/173m2
0.31
545
5155
400
3574
1.28
2.60
3.6
3.4
0.00
6.13
estimate
1.07
84
785
701
6896
3.33
2.58
20.4
17.1
4.44
4.47
e12/l
1.15
691
6802
51
325
1.61
2.57
3.4
3.9
11.07
6.19
ug/l
0.34
36
233
40
239
1.71
2.57
1.0
1.1
0.72
5.90
eliau/ml
—
10
45
257
2177
1.28
2.57
2.8
2.4
—
—
—
0
0
460
4191
1.28
2.50
3.6
3.3
63.31
57.67
ug/l
0.87
437
4002
92
670
1.43
2.50
1.8
2.0
385.16
383.10
nmol/l
0.03
83
628
273
2344
1.27
2.41
1.9
1.8
—
—
—
0
0
212
1764
1.29
2.41
1.5
1.4
2.06
2.03
g/l
0.13
137
1149
105
791
1.38
2.36
2.7
2.4
2.11
5.04
e6/l
4.67
44
335
111
845
1.37
2.34
2.4
2.8
394.41
590.57
ng/l
0.70
90
675
108
820
1.37
2.31
3.2
2.8
64.17
314.04
ng/l
1.25
53
398
77
551
1.45
2.31
1.1
1.1
—
—
—
0
0
67
469
1.47
2.25
1.6
1.6
—
—
—
0
0
188
1555
1.28
2.22
2.4
2.2
—
—
—
0
0
668
6467
1.61
2.19
10.3
9.1
23.74
23.14
u/l
0.52
652
6327
76
552
1.42
2.11
2.1
2.2
33.51
35.53
u/l
0.14
65
460
145
1167
1.31
2.10
2.4
2.4
9.68
10.41
e6/l
0.13
134
1050
473
4367
1.25
2.09
4.9
4.1
51.40
1707.88
e6/l
—
5
48
205
1728
1.26
2.06
3.0
2.7
432.53
69.10
e6/l
0.43
154
1268
177
1467
1.28
2.05
1.9
1.7
0.88
0.81
mg/l
0.20
142
1101
104
804
1.34
2.00
2.2
2.2
2.48
2.49
g/l
0.09
94
731
216
1840
1.25
1.98
2.8
2.8
2.35
2.35
mmol/l
0.42
205
1723
249
2156
1.24
1.97
2.8
2.9
32.67
26.24
u/l
0.63
236
2049
187
1568
1.26
1.96
2.9
3.3
1.02
2.99
kg/l
0.80
114
1020
635
6105
1.40
1.95
6.1
5.8
1.62
1.72
mu/l
0.91
615
5869
20
106
1.91
1.92
1.6
1.3
—
—
—
0
0
47
322
1.49
1.79
2.2
3.8
77.60
69.10
ng/l
0.36
42
294
111
881
1.31
1.79
2.2
2.2
15.55
14.65
umol/l
0.56
104
811
74
555
1.37
1.74
2.8
3.5
34.56
32.73
%
0.66
54
412
559
5308
1.26
1.68
4.6
4.4
35.99
36.69
mmol/mol
1.63
535
5087
5
14
3.59
1.62
1.2
1.1
—
—
—
0
0
13
63
2.08
1.60
1.0
1.3
—
28.80
—
0
5
587
5616
1.27
1.58
3.9
3.7
5.53
5.55
mmol/l
0.07
549
5310
22
130
1.71
1.54
2.1
2.5
0.75
1.68
index
0.82
12
65
353
3223
1.19
1.52
4.1
3.9
5.89
6.16
mmol/l
2.45
325
2888
178
1525
1.22
1.52
1.9
1.9
—
—
—
0
0
107
867
1.28
1.49
2.6
2.3
1.50
1.02
e6/l
0.46
48
409
61
456
1.37
1.49
2.7
2.4
—
—
—
0
0
67
509
1.35
1.48
3.6
5.3
1.01
1.06
mmol/l
0.80
62
472
48
346
1.42
1.45
1.6
2.2
—
—
—
0
0
11
52
2.13
1.45
1.2
1.1
125.09
117.27
pmol/l
0.25
11
52
243
2159
1.19
1.41
3.1
2.8
0.03
0.02
estimate
0.04
78
664
192
1672
1.20
1.38
2.3
2.1
2.36
2.53
mg/l
0.73
159
1443
159
1363
1.21
1.34
1.4
1.3
2.06
10.43
u/ml
4.28
63
567
169
1467
1.20
1.25
1.4
1.3
15.94
23.95
iu/ml
1.18
53
423
74
586
1.29
1.25
1.3
1.3
142.75
338.04
u/ml
0.65
68
548
20
123
1.64
1.25
1.2
1.5
—
—
—
0
0
23
147
1.58
1.24
1.0
1.1
1.34
2.70
eliau/ml
1.06
12
78
11
56
1.98
1.22
1.5
1.3
—
—
—
0
0
6
26
2.32
1.19
1.2
1.0
—
—
—
0
0
0
34
0.00
1.16
0.0
2.3
—
1314.35
—
0
34
22
142
1.57
1.15
1.2
1.2
57.20
3.62
u/ml
—
5
50
39
285
1.39
1.13
2.5
2.1
7.46
4.64
umol/l
0.52
32
212
7
31
2.27
1.10
1.1
1.0
—
—
—
0
0
70
561
1.28
1.10
3.0
3.8
4.50
4.65
pmol/l
0.84
65
507
186
1648
1.17
1.09
2.4
2.7
13.44
83.18
ng/l
0.65
76
700
108
911
1.22
1.08
2.0
2.2
2.42
2.41
mmol/l
0.22
99
811
17
105
1.63
1.07
1.5
1.6
5964.73
10329.81
e6/l
0.35
11
79
164
1441
1.18
1.06
1.5
1.5
20.79
20.35
nmol/l
0.16
140
1287
12
67
1.80
1.05
1.4
1.4
331.67
444.34
pmol/l
0.55
12
59
37
272
1.38
1.05
1.3
1.3
—
—
—
0
0
63
503
1.28
1.03
2.5
2.3
13.95
17.60
au/ml
0.41
14
66
97
818
1.22
0.99
1.2
1.3
138.95
153.23
u/ml
0.13
37
345
297
2744
1.14
0.98
3.4
3.2
0.00
0.03
estimate
2.19
76
655
179
1596
1.16
0.97
2.4
3.1
7.50
7.92
mmol/l
0.59
164
1396
17
109
1.57
0.94
2.8
3.2
18.93
25.71
mg/l
—
10
74
6
28
2.15
0.91
1.0
1.1
6.00
6.25
nmol/l
—
6
28
256
2352
1.14
0.91
1.8
1.8
1.28
1.29
mmol/l
0.10
224
2100
6
29
2.08
0.89
1.2
1.1
—
—
—
0
0
6
29
2.08
0.89
1.5
2.1
—
—
—
0
0
78
651
1.22
0.89
2.1
2.2
6.02
4.82
umol/l
0.33
61
534
11
64
1.73
0.86
1.0
1.1
1.04
1.05
ratio
0.28
11
53
28
204
1.39
0.86
1.3
1.2
—
—
—
0
0
18
120
1.51
0.86
1.4
1.1
—
—
—
0
0
42
327
1.30
0.85
1.6
1.4
—
—
—
0
0
37
283
1.32
0.85
1.2
1.1
2.72
2.96
u/ml
0.06
19
148
35
269
1.32
0.79
1.9
2.3
2.75
3.85
iu/l
0.79
18
124
20
140
1.44
0.77
1.4
1.3
25.10
5.22
u/ml
—
10
60
0
27
0.00
0.77
0.0
1.5
—
—
—
0
0
17
244
0.69
0.76
1.2
1.5
—
—
—
0
0
14
92
1.53
0.72
1.1
1.1
82.79
93.57
%
1.36
14
83
32
248
1.30
0.70
1.1
1.1
2.86
5.22
u/ml
0.78
15
132
13
85
1.54
0.69
2.3
2.1
—
—
—
0
0
22
161
1.38
0.69
1.1
1.3
305.67
221.15
u/ml
0.78
12
100
7
42
1.67
0.68
2.3
1.6
—
—
—
0
0
27
205
1.33
0.68
2.0
2.8
1.51
1.20
mmol/l
0.17
15
141
77
664
1.18
0.66
1.7
1.6
1382.84
1151.54
nmol/l
0.52
68
511
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
11
164
0.67
0.62
1.1
1.1
—
—
—
0
0
24
182
1.33
0.62
1.1
1.2
—
—
—
0
0
24
182
1.33
0.62
1.1
1.2
—
—
—
0
0
19
139
1.38
0.61
5.1
3.0
1.35
1.22
mg/l
0.22
19
123
0
21
0.00
0.60
0.0
3.5
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
16
114
1.41
0.59
1.6
1.6
9.99
10.09
g/l
0.03
16
108
70
607
1.17
0.58
1.5
1.7
243.91
297.81
mu/l
1.86
65
537
6
35
1.72
0.57
2.0
1.4
72451.33
11365.21
e6/l
—
6
24
8
54
1.49
0.57
1.5
1.6
7.41
9.34
umol/l
—
8
49
42
503
0.82
0.56
4.6
4.5
—
—
—
0
0
40
481
0.82
0.55
2.3
1.7
—
—
—
0
0
9
60
1.51
0.54
1.2
1.3
—
—
—
0
0
11
74
1.49
0.53
1.5
1.1
—
—
—
0
0
15
108
1.40
0.53
1.4
1.4
—
—
—
0
0
204
1908
1.10
0.51
3.7
3.4
0.00
0.00
estimate
1.08
81
759
18
135
1.34
0.51
1.1
1.1
—
—
—
0
0
45
381
1.19
0.50
2.1
2.2
84.15
80.34
ml/min/173m2
0.27
20
150
14
101
1.39
0.50
1.4
1.9
—
—
—
0
0
21
163
1.30
0.48
1.2
1.4
357.33
326.51
ug/g
—
9
89
24
190
1.27
0.48
6.8
7.5
16.07
15.91
%
0.11
24
183
45
383
1.19
0.48
1.2
1.2
—
—
—
0
0
7
47
1.49
0.47
1.0
1.1
1195.71
1524.45
miu/ml
—
7
47
13
94
1.39
0.46
3.2
1.9
5.91
5.22
mmol/24h
0.35
13
84
17
129
1.33
0.46
1.5
1.6
3.23
3.68
g/l
1.26
17
124
17
129
1.33
0.46
1.5
1.6
3.99
4.36
g/l
1.42
17
124
17
129
1.33
0.46
1.5
1.6
6.72
7.24
g/l
0.96
17
124
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
5
83
0.60
0.46
1.0
1.1
—
—
—
0
0
8
120
0.66
0.46
1.6
1.9
432.88
143.57
ug/l
—
8
106
103
940
1.11
0.43
1.8
1.6
1.29
1.32
%
0.30
96
851
5
32
1.57
0.42
1.2
1.5
—
—
—
0
0
10
70
1.43
0.42
1.0
1.3
—
—
—
0
0
14
105
1.34
0.41
1.0
1.6
0.00
0.00
g/l
-0.00
14
95
14
105
1.34
0.41
1.0
1.6
0.00
0.05
g/l
0.50
14
100
0
15
0.00
0.41
0.0
1.0
—
0.01
—
0
15
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
23
186
1.24
0.41
1.0
1.0
0.06
0.22
u/ml
—
6
54
16
205
0.78
0.40
1.7
2.1
12.87
4.90
ug/l
0.39
16
180
17
132
1.29
0.40
1.1
1.3
—
—
—
0
0
14
182
0.76
0.39
1.6
1.8
—
—
—
0
0
10
71
1.41
0.39
1.0
1.3
—
213.33
—
0
6
65
723
0.89
0.37
2.1
1.8
—
—
—
0
0
133
1240
1.09
0.37
2.0
2.2
294.61
296.45
umol/l
0.09
121
1137
9
69
1.31
0.37
1.0
1.1
—
—
—
0
0
16
125
1.29
0.37
1.0
1.6
2.88
2.91
g/l
0.08
16
120
5
37
1.35
0.37
1.6
1.3
—
—
—
0
0
10
72
1.39
0.37
1.0
1.9
—
—
—
0
0
5
77
0.65
0.36
1.6
1.1
—
—
—
0
0
40
348
1.16
0.35
1.5
1.8
—
—
—
0
0
37
320
1.16
0.35
1.7
1.6
—
—
—
0
0
44
499
0.87
0.35
2.2
1.7
—
—
—
0
0
43
488
0.87
0.34
1.5
1.4
—
—
—
0
0
114
1062
1.09
0.33
1.5
1.6
47525175.32
43724277.85
pmol/l
0.03
101
956
40
352
1.14
0.31
2.9
2.9
1.23
1.23
mmol/l
0.53
35
297
76
697
1.10
0.31
1.5
1.5
1.06
1.15
ratio
0.56
47
431
18
147
1.23
0.31
1.7
2.0
—
—
—
0
0
75
688
1.10
0.30
1.5
1.5
—
—
—
0
0
76
698
1.10
0.30
1.5
1.5
1.36
1.20
ratio
0.50
49
434
76
698
1.10
0.30
1.5
1.5
0.96
0.94
ratio
0.11
47
432
13
102
1.28
0.30
1.7
1.6
—
—
—
0
0
13
162
0.80
0.28
1.1
1.2
3.51
3.65
mmol/l
0.34
13
153
58
528
1.11
0.28
1.3
1.4
226.61
248.28
miu/ml
0.20
29
283
40
356
1.13
0.28
1.4
1.4
—
—
—
0
0
9
117
0.77
0.27
2.3
1.3
—
—
—
0
0
8
66
1.21
0.26
1.4
1.3
—
—
—
0
0
39
349
1.12
0.25
2.4
3.0
1.62
1.74
mmol/l
0.05
34
293
28
245
1.15
0.25
1.2
1.1
1.05
2.10
u/ml
0.87
14
123
128
1214
1.07
0.25
3.2
4.1
5.66
8.88
mg/mmol
0.59
74
751
33
371
0.88
0.25
1.1
1.1
1.61
1.58
g/l
0.36
33
371
9
75
1.20
0.25
1.1
1.1
201.56
199.80
mg/l
—
9
65
19
223
0.85
0.24
1.7
1.6
—
—
—
0
0
40
360
1.12
0.24
7.6
6.8
1.02
0.98
mmol/l
0.02
32
292
6
83
0.72
0.24
2.5
6.4
309.17
376.06
umol/l
—
6
74
92
864
1.07
0.24
1.5
1.5
—
—
—
0
0
13
158
0.82
0.23
2.5
2.8
25.26
24.89
mmol/l
0.16
13
151
23
199
1.16
0.23
4.0
5.8
24.63
24.49
mmol/l
0.07
23
191
14
115
1.22
0.23
1.0
1.8
0.00
0.46
g/l
1.21
14
107
5
40
1.25
0.22
2.2
2.4
—
—
—
0
0
34
378
0.89
0.22
1.2
1.2
0.80
0.85
g/l
0.76
34
378
20
172
1.17
0.22
1.6
1.6
—
—
—
0
0
40
363
1.11
0.21
7.7
6.8
5.21
5.07
kpa
0.25
40
349
40
363
1.11
0.21
7.7
6.8
13.92
13.23
kpa
0.35
40
349
5
42
1.19
0.21
1.2
1.4
—
—
—
0
0
5
42
1.19
0.21
1.0
1.2
—
93.83
%
—
0
6
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
2.4
—
3.12
—
0
6
0
12
0.00
0.21
0.0
1.5
—
1.20
—
0
12
141
1350
1.06
0.21
1.5
1.6
1165.05
980.59
mu/l
1.35
117
1159
0
13
0.00
0.21
0.0
1.1
—
1.96
—
0
13
0
13
0.00
0.21
0.0
2.0
—
1.69
—
0
13
39
355
1.10
0.20
2.4
3.0
5.94
5.78
kpa
0.31
39
346
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
52
1.16
0.19
1.7
1.6
5.00
5.12
mmol/l
—
6
52
44
477
0.92
0.19
5.1
5.5
106.16
104.93
mmol/l
1.83
44
477
7
61
1.15
0.17
1.0
1.3
—
—
—
0
0
20
176
1.14
0.17
1.1
1.3
340.75
442.12
mg/l
1.96
20
168
7
62
1.13
0.17
2.0
1.3
—
—
—
0
0
7
62
1.13
0.17
1.0
1.3
—
—
—
0
0
13
110
1.19
0.17
1.0
1.1
—
—
—
0
0
5
67
0.74
0.17
3.8
2.1
10.84
10.16
u/ml
—
5
67
80
760
1.06
0.16
1.6
1.5
59.45
60.25
ug/l
0.06
63
649
37
341
1.09
0.16
7.4
5.5
1.20
1.18
mmol/l
0.09
37
333
7
87
0.80
0.14
1.6
1.2
—
—
—
0
0
7
87
0.80
0.14
1.0
1.1
—
—
—
0
0
13
113
1.15
0.13
1.8
1.2
—
—
—
0
0
9
110
0.82
0.13
2.8
2.2
135.56
131.70
g/l
—
9
92
24
219
1.10
0.13
1.1
1.1
0.47
4.91
u/ml
3.53
11
110
25
272
0.92
0.12
1.8
2.0
67.28
67.52
g/l
0.05
25
257
556
5519
1.03
0.12
3.4
3.3
1.13
1.16
mmol/l
0.45
533
5267
41
386
1.07
0.11
1.7
1.8
3.66
3.20
mg/l
0.21
34
269
12
105
1.15
0.11
1.1
1.1
—
—
—
0
0
28
260
1.08
0.11
2.2
2.0
36.18
38.49
u/l
0.36
28
245
18
198
0.91
0.11
1.7
1.9
—
—
—
0
0
80
828
0.96
0.10
1.6
1.6
3.43
3.36
mmol/l
0.20
51
548
5
45
1.11
0.10
1.2
1.3
63.60
67.40
umol/l
—
5
45
31
329
0.94
0.09
1.5
1.5
0.24
0.25
mg/l
—
10
135
51
532
0.96
0.09
1.1
1.4
—
—
—
0
0
6
56
1.07
0.08
1.3
1.1
—
—
—
0
0
5
63
0.79
0.08
1.0
1.3
—
—
—
0
0
15
164
0.91
0.08
1.1
1.3
1.80
1662.14
e6/l
—
10
127
6
71
0.84
0.07
1.5
1.2
—
—
—
0
0
6
71
0.84
0.07
1.5
1.2
—
—
—
0
0
6
70
0.86
0.07
1.5
1.2
—
—
—
0
0
7
81
0.86
0.07
1.0
1.1
—
—
—
0
0
99
967
1.03
0.07
2.3
2.3
5224.09
6972.84
u/l
0.26
47
418
9
86
1.05
0.07
1.9
1.2
—
—
—
0
0
9
86
1.05
0.07
1.0
1.3
—
—
—
0
0
9
86
1.05
0.07
1.0
1.3
—
—
—
0
0
20
187
1.07
0.06
8.7
7.8
24.39
24.38
mmol/l
0.01
20
182
592
5898
1.02
0.06
4.0
3.8
1.56
1.53
mmol/l
0.97
572
5651
15
162
0.92
0.06
1.1
1.2
11.10
16.58
e6/l
—
10
120
594
5919
1.02
0.06
4.1
3.9
4.79
4.76
mmol/l
0.40
578
5695
33
316
1.05
0.05
2.3
2.0
5.30
6.33
iu/ml
—
9
71
11
101
1.09
0.04
1.7
1.3
—
—
—
0
0
597
5957
1.01
0.03
4.4
4.2
2.84
2.82
mmol/l
0.22
576
5712
12
128
0.94
0.02
2.0
1.3
—
—
—
0
0
66
650
1.02
0.02
1.6
1.7
—
—
—
0
0
22
228
0.96
0.02
2.3
1.5
0.01
0.36
iu/ml
—
5
28
31
302
1.03
0.02
1.8
2.4
4.61
4.57
kpa
0.04
31
296
18
174
1.04
0.00
1.1
1.1
13.22
15.30
au/ml
—
5
56
15
145
1.04
0.00
3.3
4.1
1.47
1.64
%
0.45
15
138
19
185
1.03
0.00
1.3
1.2
—
—
—
0
0
14
136
1.03
0.00
1.2
1.5
34.21
33.84
nmol/l
0.01
14
122
105
1055
0.99
0.00
1.9
1.8
3.27
3.26
ratio
0.03
75
767
11
111
0.99
0.00
1.3
2.5
1.02
0.93
nmol/l
0.21
11
95
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
44.34
—
0
7
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
7.09
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
59
1.02
-0.00
2.0
1.2
—
52.43
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
10.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
52
520
1.00
-0.00
1.4
1.6
52.83
58.50
ug/l
0.60
52
520
6
68
0.88
-0.00
1.5
1.2
—
—
—
0
0
6
68
0.88
-0.00
1.5
1.2
—
—
—
0
0
6
65
0.92
-0.00
1.5
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
26.50
—
0
5
5
50
1.00
-0.00
1.2
1.3
108.60
67.80
ug/l
—
5
50
0
6
0.00
-0.00
0.0
4.5
—
—
—
0
0
8
81
0.99
-0.00
2.9
1.6
0.50
0.47
e9/l
—
8
81
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.4
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
59
590
1.00
-0.00
1.8
1.8
—
—
—
0
0
6
68
0.88
-0.00
1.5
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_BREAST and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_BREAST.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_BREAST – Congenital malformations of breast
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data