Other infections specific to the perinatal period

P16_OTH_INFECTIONS_SPECIFIC_PERINA_PERIOD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P39
  • Cause of death: ICD-10 P39

2 out of 7 registries used, show all original rules.

221

4. Check minimum number of events

None

221

5. Include endpoints

None

221

6. Filter based on genotype QC (FinnGen only)

200

Control definitions (FinnGen only)

Control exclude
P16_INFECTIONS_SPECIFIC_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P3
Name in latin
Alii infectiones temporis perinatalis specificae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15148 6214 8934
Only index persons 9358 3723 5635
Unadjusted period prevalence (%)
Whole population 0.22 0.18 0.25
Only index persons 0.18 0.14 0.22
Median age at first event (years)
Whole population - 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 200 106 94
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
210
Matched controls
2098
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P39.9
ICD-10 Finland
Infection specific to the perinatal period, unspecified
+∞
198.9
158
*
P39.1
ICD-10 Finland
Neonatal conjunctivitis and dacryocystitis
+∞
26.6
25
*
P01.10
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery
31.3
15.5
20
7
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
11.6
12.6
23
22
P39.0
ICD-10 Finland
Neonatal infective mastitis
+∞
11.6
11
*
P39.4
ICD-10 Finland
Neonatal skin infection
+∞
11.6
11
*
P36.90
ICD-10 Finland
Suspected bacterial sepsis of newborn
+∞
11.6
11
*
P07.3
ICD-10 Finland
Other preterm infants
3.4
6.1
22
69

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
28
108
2.83
5.48
3.0
3.1
—
—
—
0
0
23
108
2.27
3.03
8.5
5.3
0.33
0.43
%
—
6
37
6
9
6.81
2.88
2.2
1.4
32.33
32.89
pg
—
6
9
0
73
0.00
2.84
0.0
5.1
—
7.33
—
0
55
51
326
1.74
2.82
3.7
4.0
7.39
7.38
ph
0.49
28
229
23
112
2.18
2.79
8.0
6.4
0.00
0.03
%
—
5
35
54
352
1.72
2.78
3.6
3.5
0.00
0.00
estimate
-0.00
26
129
42
256
1.80
2.72
4.2
4.7
—
—
—
0
0
23
115
2.12
2.62
9.0
6.4
0.00
0.00
%
—
6
30
23
115
2.12
2.62
8.0
6.4
0.20
0.62
%
—
5
39
72
518
1.59
2.51
3.2
3.0
0.00
0.01
estimate
0.50
24
112
0
65
0.00
2.46
0.0
1.1
—
—
—
0
0
39
586
0.59
2.33
3.4
3.6
—
—
estimate
—
0
0
119
969
1.52
2.33
10.9
12.6
0.00
0.00
e9/l
-0.00
93
745
57
395
1.61
2.30
3.4
2.7
0.00
0.00
estimate
-0.00
26
111
6
14
4.37
2.16
1.0
1.1
—
—
—
0
0
167
1503
1.54
1.73
12.7
13.1
3.89
3.88
mmol/l
0.20
162
1450
5
13
3.91
1.72
1.2
1.0
—
—
—
0
0
167
1507
1.52
1.67
12.7
13.1
139.56
139.54
mmol/l
0.05
162
1463
7
25
2.86
1.66
7.0
7.2
4.56
5.52
pmol/l
—
7
25
5
15
3.38
1.53
1.0
1.1
—
—
—
0
0
178
1639
1.56
1.50
14.7
16.3
13.09
12.98
%
0.71
172
1615
29
424
0.63
1.48
2.9
3.7
—
—
—
0
0
67
833
0.71
1.48
1.6
1.9
0.31
2.11
u/ml
3.73
12
161
24
150
1.68
1.45
1.4
1.4
—
—
—
0
0
5
16
3.17
1.44
1.0
1.1
—
—
—
0
0
42
306
1.46
1.33
3.1
3.5
468.36
621.12
mosm/kgh2o
3.68
35
277
18
107
1.74
1.30
2.6
2.9
4.82
5.07
pmol/l
0.74
18
99
90
751
1.35
1.29
3.9
3.5
0.00
0.00
estimate
-0.00
27
130
11
55
2.05
1.29
2.9
6.0
229.09
453.73
mg/l
1.05
11
55
6
25
2.44
1.25
1.7
4.8
8.55
9.15
kpa
—
6
25
6
25
2.44
1.25
1.7
4.8
5.63
4.85
kpa
—
6
25
90
755
1.33
1.24
4.0
3.6
0.00
0.00
estimate
-0.00
28
128
89
746
1.33
1.23
3.9
3.5
0.00
0.00
estimate
-0.00
28
134
25
166
1.57
1.21
2.2
2.5
6.93
5.64
u/l
0.48
17
108
59
470
1.35
1.13
4.3
4.6
0.09
0.22
e6/l
1.22
38
346
44
564
0.72
1.12
2.0
1.6
—
—
—
0
0
8
41
1.99
1.10
4.1
3.9
2.61
3.11
e9/l
—
8
41
52
408
1.36
1.09
6.1
5.2
—
—
—
0
0
7
32
2.23
1.09
2.0
4.9
7.39
7.38
ph
—
7
32
182
1712
1.47
1.08
11.9
11.6
22.41
22.28
mg/l
0.02
129
1198
15
92
1.68
1.00
1.5
1.6
—
—
—
0
0
0
29
0.00
0.98
0.0
1.1
—
—
—
0
0
199
1914
1.74
0.98
16.6
17.4
272.58
267.38
e9/l
0.52
185
1840
9
50
1.83
0.98
3.6
6.3
—
—
—
0
0
23
159
1.50
0.96
2.2
2.5
4.76
7.36
iu/l
1.62
17
105
36
272
1.39
0.95
1.7
1.4
17.89
18.50
nmol/l
0.12
31
238
26
354
0.70
0.94
1.3
1.9
—
—
—
0
0
199
1917
1.71
0.93
16.6
17.3
4.66
4.66
e12/l
0.05
186
1839
6
29
2.10
0.90
1.2
1.1
—
—
—
0
0
199
1919
1.69
0.89
16.6
17.3
6.75
6.58
e9/l
0.59
186
1838
13
80
1.66
0.86
1.5
1.2
—
—
—
0
0
8
45
1.81
0.85
22.1
14.8
67.63
69.84
%
—
8
45
62
518
1.28
0.84
5.1
4.7
10.03
24.61
e6/l
1.84
42
395
42
336
1.31
0.78
4.8
3.5
8.02
9.04
e6/l
0.19
35
305
0
27
0.00
0.78
0.0
3.4
—
5.40
—
0
16
27
353
0.73
0.78
1.3
1.8
—
—
—
0
0
6
34
1.78
0.77
4.8
5.4
—
—
—
0
0
0
28
0.00
0.76
0.0
1.9
—
41.36
—
0
28
27
352
0.73
0.76
1.3
1.9
—
—
—
0
0
27
352
0.73
0.76
1.3
1.9
—
—
—
0
0
9
53
1.73
0.76
1.7
1.0
0.99
0.79
g/l
—
9
53
8
131
0.59
0.76
1.1
1.4
—
—
—
0
0
26
336
0.74
0.70
1.3
1.3
—
—
—
0
0
5
27
1.87
0.69
1.0
1.0
—
—
—
0
0
28
216
1.34
0.67
1.3
1.2
8.80
13.96
iu/ml
—
5
40
23
172
1.38
0.67
5.3
6.4
349.39
298.02
umol/l
1.29
23
161
26
331
0.75
0.64
1.3
1.9
—
—
—
0
0
177
1693
1.28
0.62
7.8
8.0
—
—
—
0
0
84
749
1.20
0.61
2.3
2.3
—
—
—
0
0
12
173
0.67
0.61
2.1
2.1
—
—
—
0
0
0
20
0.00
0.60
0.0
2.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
8
53
1.53
0.59
1.0
1.0
1.43
1.50
g/l
—
8
53
48
406
1.23
0.59
1.7
1.6
104.63
98.09
pmol/l
0.39
26
210
0
23
0.00
0.58
0.0
1.3
—
20.17
—
0
6
0
23
0.00
0.58
0.0
1.3
—
28.29
—
0
7
22
282
0.75
0.57
1.4
1.9
—
—
—
0
0
30
241
1.28
0.56
2.2
2.3
—
—
—
0
0
47
403
1.21
0.51
2.8
1.9
—
—
—
0
0
7
47
1.50
0.48
1.6
1.5
—
—
—
0
0
10
68
1.49
0.47
2.9
1.6
—
—
—
0
0
36
303
1.23
0.47
6.4
8.4
7.40
7.41
ph
0.30
28
249
19
241
0.77
0.47
1.5
1.7
—
—
—
0
0
35
294
1.23
0.46
1.4
1.7
—
—
—
0
0
71
638
1.17
0.46
6.3
5.5
64.13
60.16
e6/l
0.03
43
414
9
128
0.69
0.45
1.2
1.3
—
—
—
0
0
19
149
1.30
0.43
1.7
1.4
497.17
51145453.23
pmol/l
0.50
12
131
5
32
1.57
0.42
3.8
6.0
—
—
—
0
0
0
16
0.00
0.41
0.0
2.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
17.56
—
0
16
20
247
0.79
0.41
1.5
2.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.48
0.40
1.0
1.3
0.88
4.05
u/ml
—
5
34
31
262
1.21
0.39
6.0
8.3
—
—
—
0
0
31
262
1.21
0.39
3.0
5.2
0.60
1.37
mg/l
1.18
19
178
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
44
386
1.18
0.38
3.2
2.3
—
—
—
0
0
8
113
0.70
0.38
2.4
2.1
—
29.73
—
0
6
24
199
1.23
0.36
1.3
1.2
1.16
8.43
u/ml
—
9
65
12
156
0.75
0.36
1.2
2.3
—
—
—
0
0
116
1099
1.12
0.33
10.4
12.0
3.60
3.47
e9/l
0.27
98
934
14
174
0.79
0.31
2.0
1.9
—
—
—
0
0
69
744
0.89
0.30
1.6
1.8
1.64
1.64
g/l
0.00
37
419
167
1620
1.15
0.30
9.2
9.6
24.12
24.53
u/l
0.12
159
1565
31
353
0.86
0.30
1.4
1.6
—
—
—
0
0
34
299
1.16
0.29
3.9
4.4
3.60
3.16
e6/l
0.09
15
160
5
72
0.69
0.26
1.0
1.5
—
—
—
0
0
9
72
1.26
0.26
20.0
12.1
0.64
0.56
%
—
9
72
69
643
1.11
0.25
3.7
3.3
6.39
6.37
ph
0.03
31
294
9
75
1.21
0.25
1.3
1.3
—
—
—
0
0
9
77
1.18
0.24
4.0
3.0
44.67
53.70
%
—
9
77
6
81
0.73
0.24
1.0
1.9
—
—
—
0
0
92
967
0.91
0.24
4.6
4.0
68.96
50.78
ug/l
0.33
87
922
18
153
1.19
0.23
26.2
16.1
1.25
1.32
mmol/l
0.17
18
146
11
88
1.26
0.23
1.0
1.0
—
—
—
0
0
40
437
0.89
0.22
2.1
1.8
—
—
—
0
0
5
41
1.22
0.22
1.4
1.3
—
—
—
0
0
8
102
0.78
0.21
2.3
2.2
—
—
—
0
0
5
42
1.19
0.21
5.2
7.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
34.70
—
0
10
0
10
0.00
0.21
0.0
1.2
—
230.05
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
27.00
—
0
10
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
15
126
1.20
0.21
1.1
1.3
3.13
3.08
mmol/l
—
6
74
0
13
0.00
0.21
0.0
11.1
—
0.59
—
0
13
0
13
0.00
0.21
0.0
2.4
—
—
—
0
0
164
1674
0.90
0.21
13.7
15.6
334.94
335.24
g/l
0.17
164
1654
6
48
1.26
0.20
1.3
5.2
30.17
28.17
%
—
6
48
6
48
1.26
0.20
1.7
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
7.4
—
209.56
—
0
9
6
50
1.20
0.20
1.3
5.1
9.33
8.46
%
—
6
50
6
50
1.20
0.20
1.3
5.1
71.50
68.52
%
—
6
50
76
720
1.09
0.19
10.8
12.4
1.22
1.22
mmol/l
0.39
69
655
28
253
1.12
0.17
2.1
2.3
11.67
14.29
ng/l
—
9
87
5
66
0.75
0.17
1.0
1.2
—
—
—
0
0
8
69
1.16
0.16
1.9
4.1
—
—
—
0
0
6
76
0.78
0.16
36.8
19.4
25.17
23.74
mmol/l
—
6
76
49
460
1.08
0.15
2.0
1.9
1.60
1.16
mmol/l
0.42
43
428
59
621
0.93
0.15
5.7
9.8
—
—
—
0
0
79
758
1.07
0.14
9.5
11.0
—
—
—
0
0
147
1497
0.94
0.13
4.8
4.3
1.86
1.92
mu/l
0.29
134
1419
11
94
1.18
0.13
1.1
1.3
—
—
—
0
0
36
336
1.08
0.13
18.6
15.5
25.15
24.95
mmol/l
0.20
36
336
34
317
1.09
0.12
11.6
11.5
23.09
23.77
mmol/l
0.68
34
317
33
308
1.08
0.12
14.0
15.1
—
—
—
0
0
108
1106
0.95
0.11
2.5
2.4
5.55
5.32
mmol/l
0.40
93
997
39
412
0.93
0.11
3.5
3.9
86.63
82.55
ug/g
0.07
33
327
60
624
0.94
0.11
2.9
2.3
—
—
—
0
0
100
973
1.05
0.10
3.6
3.3
36.01
35.67
mmol/mol
0.10
93
925
110
1073
1.05
0.10
9.6
11.1
0.19
0.20
e9/l
0.12
93
927
18
197
0.90
0.10
4.3
3.2
2224.13
1182.84
ng/l
—
8
94
107
1045
1.05
0.09
9.4
10.5
0.55
0.54
e9/l
0.19
90
886
26
243
1.08
0.09
1.3
1.4
—
13.13
—
0
8
107
1046
1.04
0.09
9.4
10.5
0.04
0.03
e9/l
2.03
90
887
6
57
1.05
0.08
1.3
5.6
18.83
16.47
%
—
6
57
14
154
0.90
0.08
26.9
14.1
105.71
105.40
mmol/l
0.09
14
154
16
147
1.09
0.07
1.7
2.0
211.60
165.22
u/ml
—
10
65
9
83
1.09
0.07
7.3
3.4
1.48
0.08
e6/l
—
9
78
108
1061
1.03
0.06
3.0
3.1
2.49
2.60
mmol/l
0.91
101
1012
20
188
1.07
0.05
1.5
1.6
—
—
—
0
0
10
91
1.10
0.04
1.2
1.1
—
—
—
0
0
23
221
1.04
0.03
12.2
15.7
6.04
5.16
mmol/l
0.49
23
216
32
329
0.97
0.02
12.1
11.4
5.09
4.98
kpa
0.13
32
317
35
341
1.03
0.02
11.6
11.8
5.94
5.93
kpa
0.03
35
328
18
187
0.96
0.01
1.2
1.3
3.72
3.64
u/ml
0.01
12
130
35
342
1.03
0.01
11.5
11.9
7.37
7.37
ph
0.06
23
240
108
1071
1.02
0.01
9.4
10.4
2.20
2.13
e9/l
0.34
92
933
41
417
0.98
0.01
2.8
2.9
1.24
1.02
kg/l
0.49
20
243
97
962
1.01
0.01
7.8
6.1
113.30
110.95
u/l
0.12
90
908
107
1062
1.01
0.01
2.8
3.1
1.34
1.40
mmol/l
1.02
100
1012
109
1082
1.01
0.01
3.0
3.2
4.18
4.32
mmol/l
1.10
102
1037
15
156
0.96
0.01
1.8
2.4
—
—
—
0
0
136
1353
1.01
0.00
4.4
3.7
14.45
14.43
pmol/l
0.03
120
1205
10
96
1.04
0.00
1.4
1.1
—
—
—
0
0
61
609
1.00
0.00
1.9
1.8
—
—
—
0
0
42
415
1.01
0.00
2.6
2.0
—
—
—
0
0
11
115
0.95
0.00
1.1
1.1
—
—
—
0
0
30
304
0.98
0.00
2.0
1.7
—
—
—
0
0
34
337
1.01
0.00
11.7
11.9
0.98
1.31
mmol/l
0.18
28
279
0
6
0.00
-0.00
0.0
2.5
—
3.52
—
0
6
0
6
0.00
-0.00
0.0
2.5
—
107.33
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
12.4
—
46.36
—
0
7
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
98.83
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
236.57
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
2050.00
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
803.71
—
0
7
9
97
0.92
-0.00
3.8
11.0
118.56
372.40
mg/l
—
9
80
6
67
0.89
-0.00
1.0
1.1
—
—
—
0
0
7
73
0.96
-0.00
32.0
20.1
97.49
95.44
%
—
7
73
0
6
0.00
-0.00
0.0
2.5
—
1.20
—
0
6
0
7
0.00
-0.00
0.0
4.4
—
4.26
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.2
—
—
—
0
0
7
72
0.97
-0.00
32.0
20.4
0.43
0.65
%
—
7
72
8
82
0.97
-0.00
1.3
1.7
26.88
17.48
ng/l
—
8
82
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
7
75
0.93
-0.00
32.0
19.6
0.97
1.07
%
—
7
75
6
66
0.91
-0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
107.60
—
0
5
0
8
0.00
-0.00
0.0
9.3
—
797.38
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
26.57
—
0
7

Mortality – FinRegistry

Association

Association between endpoint P16_OTH_INFECTIONS_SPECIFIC_PERINA_PERIOD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_INFECTIONS_SPECIFIC_PERINA_PERIOD.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_OTH_INFECTIONS_SPECIFIC_PERINA_PERIOD – Other infections specific to the perinatal period

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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