No definition available.
Medullary carcinoma of thyroid gland, including Hilmo
C3_THYROID_MEDULLARY_WIDE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
85 |
4. Check minimum number of eventsNone |
85 |
5. Include endpointsNone |
85 |
6. Filter based on genotype QC (FinnGen only) |
75 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Medullary carcinoma of thyroid gland, including Hilmo
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of thyroid gland, including Hilmo
- Malignant neoplasm of endocrine gland, including Hilmo
- Disorders of the thyroid gland
- Solid cancers, including Hilmo
- Malignant neoplasm, wide definition
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 75 | 54 | 21 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 49.01 | 46.25 | 56.10 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 77
- Matched controls
- 770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C73.94
ICD-10 Finland
Medullary thyroid carcinoma (thyroid)
+∞
98.4
72
*
104
Kela drug reimbursment
Thyroid insufficiency
70.4
80.8
58
32
EP1AE
NOMESCO Finland
Neck ultrasound examination
64.8
67.9
42
14
H03AA01
ATC
levothyroxine sodium; systemic
70.4
42.9
72
130
8345/3-C73.9
ICD-O-3
Medullary thyroid carcinoma of thyroid gland
+∞
40.2
35
*
BAA60
NOMESCO Finland
Total thyroidectomy
81.5
38.7
42
11
8510/3-C73.9
ICD-O-3
Medullary carcinoma, NOS, of thyroid gland
+∞
36.4
32
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
82.2
33.4
36
8
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
+∞
24.2
22
*
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
+∞
23.1
21
*
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
+∞
21.9
20
*
130
Kela drug reimbursment
Malignant tumour
+∞
20.8
19
*
C73.99
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland), other or unspecified histology
+∞
20.8
19
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
19.6
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
6.2
14.2
36
95
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
14.0
13
*
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
+∞
14.0
13
*
JN4BD
NOMESCO Finland
Extensive body CT
19.1
12.0
18
12
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
11.8
11
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
10.7
10
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.6
10.0
39
141
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
35.0
9.7
12
*
A11CC03
ATC
alfacalcidol; systemic
35.0
9.7
12
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
113.4
9.6
10
*
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
+∞
9.6
9
*
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
+∞
9.6
9
*
T71
ICPC
Malignant neoplasm thyroid
+∞
9.6
9
*
19399
ICD-8 Finland
Malignant neoplasm of thyroid gland
+∞
8.5
8
*
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
+∞
8.5
8
*
PJD91
NOMESCO Finland
Excision of lymph nodes in neck, 1 to 2 areas in total
+∞
8.5
8
*
JN6AD
NOMESCO Finland
CT of torso and neck
37.7
8.3
10
*
N02AA05
ATC
oxycodone; systemic
4.9
8.2
22
58
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.9
8.2
42
180
Z31.5
ICD-10 Finland
Genetic counselling
10.7
8.0
15
17
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
28.3
7.8
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
4.9
7.7
20
51
XX3DW
NOMESCO Finland
Time consuming IT work
11.1
7.7
14
15
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
7.4
7
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
7.4
7
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
+∞
7.4
7
*
C739, ,
ICD-10 Finland
+∞
7.4
7
*
C73.93
ICD-10 Finland
Anaplastic thyroid carcinoma (thyroid)
+∞
7.4
7
*
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
18.8
6.9
10
6
Z51.5
ICD-10 Finland
Palliative care
25.1
6.8
9
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
75.9
6.5
7
*
BC1AD
NOMESCO Finland
CT of adrenal glands
75.9
6.5
7
*
WZC30
NOMESCO Finland
Teaching
4.4
6.5
19
53
106
Kela drug reimbursment
Hypoparathyroidism
+∞
6.3
6
*
WF002
NOMESCO Finland
Radical radiotherapy
+∞
6.3
6
*
1930D
ICD-9 Finland
Malignant neoplasm of thyroid gland[CARCINOMA MEDULLARE THYREOIDEAE]
+∞
6.3
6
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
H01CB03
ATC
lanreotide; parenteral
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
59
32
75.59
83.00
9.6
1.8
77.94
2.28
ug/l
0.67
54
23
63
0
+∞
81.21
11.3
0.0
679.47
—
pmol/l
—
45
0
28
5
86.19
26.16
5.6
1.2
16.04
—
u/ml
—
7
0
23
6
53.51
19.90
1.8
1.0
—
—
—
0
0
67
283
11.53
16.42
13.0
5.1
1.21
1.22
mmol/l
0.51
67
259
25
85
3.87
6.60
5.7
1.9
0.82
0.84
mmol/l
0.54
25
78
51
296
3.14
5.39
3.2
2.3
—
—
estimate
—
0
0
18
69
3.10
3.80
1.8
1.7
478.61
397.98
nmol/l
0.25
18
64
51
333
2.57
3.74
10.8
3.6
9.86
11.27
umol/l
0.90
51
311
19
76
2.99
3.73
5.2
4.2
1.06
1.03
mmol/l
0.18
19
68
9
18
5.51
3.49
1.8
1.8
149.37
2.80
ug/l
—
9
18
28
153
2.30
2.89
2.9
1.7
—
—
—
0
0
52
371
2.24
2.74
8.8
5.7
3.69
4.24
e9/l
1.05
46
318
11
39
3.12
2.46
12.3
2.5
1.27
1.22
mmol/l
0.94
11
33
6
12
5.32
2.45
4.7
1.8
13.40
9.22
pmol/l
—
6
12
7
23
3.24
1.85
8.3
3.3
2.69
1.45
mmol/l
—
7
18
30
203
1.78
1.59
2.4
3.0
691.50
1009.82
ng/l
0.55
24
171
11
53
2.25
1.47
5.8
8.2
124.36
124.75
g/l
0.02
11
53
7
32
2.30
1.11
2.7
10.3
25.96
24.97
mmol/l
—
7
32
11
62
1.90
1.00
1.6
2.0
29.18
30.71
u/l
0.19
11
49
0
30
0.00
0.99
0.0
1.4
—
—
—
0
0
0
30
0.00
0.99
0.0
1.5
—
1027.34
—
0
22
13
78
1.80
0.99
3.2
2.6
4.83
4.66
umol/l
0.09
13
68
24
313
0.66
0.87
2.0
2.0
1.24
1.38
mmol/l
0.57
24
274
9
53
1.79
0.79
4.7
2.9
—
—
—
0
0
12
76
1.69
0.77
5.9
6.6
105.33
104.86
mmol/l
0.18
12
76
11
68
1.72
0.76
1.9
1.6
—
—
—
0
0
7
41
1.78
0.72
2.6
1.4
—
—
—
0
0
13
88
1.57
0.66
2.0
1.7
—
—
—
0
0
10
65
1.62
0.59
2.0
1.7
—
—
—
0
0
6
36
1.72
0.58
1.3
1.9
0.87
1.20
%
—
6
36
6
38
1.63
0.56
7.0
10.6
0.40
0.66
%
—
6
38
22
176
1.35
0.49
2.6
2.9
0.56
0.52
e6/l
0.03
16
119
0
19
0.00
0.39
0.0
1.5
—
1.56
—
0
10
0
19
0.00
0.39
0.0
1.5
—
1.25
—
0
10
0
19
0.00
0.39
0.0
1.5
—
1.08
—
0
10
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
17
205
0.78
0.33
3.1
3.3
0.20
0.00
estimate
—
5
58
5
41
1.23
0.22
8.4
10.1
1.24
1.69
%
—
5
41
15
127
1.22
0.21
1.2
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
8.60
—
0
5
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
3.2
—
14.07
—
0
10
11
133
0.80
0.21
1.5
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
94.40
—
0
5
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
2.39
—
0
8
22
245
0.86
0.19
3.3
4.0
30.24
5.21
mg/mmol
0.41
16
148
7
59
1.20
0.18
1.6
2.6
0.04
0.20
e6/l
—
7
52
35
376
0.87
0.18
3.0
3.8
0.14
0.00
estimate
—
7
67
5
66
0.74
0.17
2.2
2.4
—
—
—
0
0
44
415
1.14
0.17
2.5
3.0
—
—
—
0
0
6
79
0.74
0.16
11.5
5.8
—
—
—
0
0
69
674
1.23
0.14
20.2
12.3
29.19
21.03
mg/l
1.17
59
525
30
279
1.12
0.14
3.8
3.4
21.36
46.29
ng/l
1.03
23
187
35
368
0.91
0.10
2.8
3.7
0.00
0.00
estimate
—
6
71
5
46
1.09
0.10
1.4
2.3
21.54
14.03
nmol/l
—
5
41
18
166
1.11
0.08
2.2
3.7
1.01
1.02
kg/l
1.37
12
105
36
375
0.92
0.08
2.8
3.7
0.00
0.00
estimate
—
8
73
6
73
0.81
0.08
2.0
2.6
—
—
—
0
0
13
118
1.12
0.07
2.2
2.7
0.22
0.95
e6/l
—
8
52
21
197
1.09
0.07
2.4
3.8
0.25
0.00
estimate
—
8
70
10
111
0.89
0.06
2.3
3.0
1.20
4.60
e6/l
—
5
46
30
311
0.94
0.04
1.8
1.9
93.14
105.86
pmol/l
0.75
13
149
49
480
1.06
0.04
3.6
3.2
60.76
45.08
u/l
0.41
49
463
23
221
1.06
0.03
2.4
3.0
—
—
—
0
0
5
50
1.00
0.00
3.0
3.0
23.02
4.84
ug/l
—
5
44
8
81
0.99
0.00
1.9
1.5
1.23
1.50
%
—
8
75
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
5.40
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
34.14
—
0
5
0
7
0.00
-0.00
0.0
2.9
—
59.71
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
5.43
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
2.52
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
43.06
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
52.26
—
0
8
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_THYROID_MEDULLARY_WIDE – Medullary carcinoma of thyroid gland, including Hilmo
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).