Idiopathic hypercalciuria

E4_IDIOPATHIC_HYPERCALCIURIA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519870

1. Apply sex-specific rule

None

519870

2. Check conditions

None

519870

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E83.58
  • Cause of death: ICD-10 E83.58

2 out of 7 registries used, show all original rules.

213

4. Check minimum number of events

None

213

5. Include endpoints

None

213

6. Filter based on genotype QC (FinnGen only)

208

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 208 111 97
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 55.15 56.98 53.06

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
213
Matched controls
2130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E83.58
ICD-10 Finland
Idiopathic hypercalciuria
+∞
308.4
213
*
N20.1
ICD-10 Finland
Calculus of ureter
26.9
83.0
62
32
N20.0
ICD-10 Finland
Calculus of kidney
35.0
76.7
51
19
N20.9
ICD-10 Finland
Urinary calculus, unspecified
33.2
69.9
47
18
KH1AD
NOMESCO Finland
CT of urinary organs
22.6
57.6
45
25
C03AA03
ATC
hydrochlorothiazide; oral
9.0
38.5
55
79
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
8.0
31.9
50
79
M05BA04
ATC
alendronic acid; oral
8.6
31.9
46
66
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
45.0
25.7
31
8
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
5.3
25.1
63
156
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
30.0
23.4
31
12
UKC02
NOMESCO Finland
Cystoscopy
4.3
18.5
58
169
E21.0
ICD-10 Finland
Primary hyperparathyroidism
18.7
16.5
25
15
KAE12
NOMESCO Finland
Retrograde ureteronephroscopic lithotripsy in pelvis of kidney
61.2
15.0
17
*
E83.50
ICD-10 Finland
Hypercalcemia
23.1
15.0
21
10
M81.5
ICD-10 Finland
Idiopathic osteoporosis
86.2
14.8
16
*
KH1AA
NOMESCO Finland
Urinary tract X-ray examination without contrast
18.2
13.3
20
12
N20.2
ICD-10 Finland
Calculus of kidney with calculus of ureter
34.4
12.8
16
5
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
26.2
12.7
17
7
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
19.5
12.3
18
10
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
22.9
12.2
17
8
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
20.4
11.8
17
9
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
24.6
11.8
16
7
M81.9
ICD-10 Finland
Osteoporosis, unspecified
8.3
10.2
22
29
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.3
9.5
26
67
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
9.3
91
492
L95
ICPC
Osteoporosis
5.2
9.3
20
42
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
16.5
9.2
14
9
R31
ICD-10 Finland
Unspecified haematuria
3.6
9.1
33
104
KBT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of ureter
28.8
8.6
11
*
M05BX04
ATC
denosumab; parenteral
4.1
8.3
24
64
KBV10
NOMESCO Finland
Removal of stent from ureter
34.8
8.1
10
*
M80.5
ICD-10 Finland
Idiopathic osteoporosis with pathological fracture
34.8
8.1
10
*
N21.0
ICD-10 Finland
Calculus in bladder
19.2
7.7
11
6
KCE02
NOMESCO Finland
Transluminal endoscopic extraction of calculus from bladder
26.1
7.6
10
*
E83.59
ICD-10 Finland
Other disorders of calcium metabolism
82.9
7.5
8
*
M81.8
ICD-10 Finland
Other osteoporosis
20.9
7.2
10
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
6.6
88
526
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
6.9
6.5
15
23
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
7.4
6.3
14
20
M821, E8358,
ICD-10 Finland
+∞
6.3
6
*
XQ800
NOMESCO Finland
Prick test
3.2
6.2
25
84
D86.0
ICD-10 Finland
Sarcoidosis of lung
7.6
6.0
13
18

TimeCodeWAS

TODO / Current known limitations:

  • Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
  • Legend / how to read the glyphs.
  • Proper column names.
  • Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
  • Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
  • Download CSV not working.
  • No filters and sorters.
  • Limited amount of endpoints with TimeCodeWAS data.
  • Cross-links to Risteys lab test pages for lab test codes.
OMOP Concept
ln(OR) -5y
ln(OR) -1y
ln(OR) -1m
ln(OR) d0
ln(OR) +1m
ln(OR) +1y
ln(OR) +5y
MCC -5y
MCC -1y
MCC -1m
MCC d0
MCC +1m
MCC +1y
MCC +5y
Idiopathic hypercalciuria
E83.58 (2000501539)
Calculus of ureter
N20.1 (45582395)
SMOKING - SMOKE2: no - SMOKE3: never - SMOKE5: Unspecified
SMOKING-2-3-0 (2002330113)
Body height measure
50373000 (4177340)
Body mass index
60621009 (4245997)
Measurement of bone density from two or more locations with X-ray
NK6QA (2001308500)
hydrochlorothiazide; oral
C03AA03 (21601466)
hydrochlorothiazide and potassium-sparing agents
C03EA01 (21601543)
Calcium [Moles/time] in 24 hour Urine
14637-3 (3010838)
Lysozyme [Mass/volume] in Serum or Plasma
2589-0 (3012110)
Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma
2742-5 (3034780)
Calculus of kidney
N20.0 (45567830)
Essential (primary) hypertension
I10 (45591453)
Outpatient Visit
OP (9202)
Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
19072-8 (3016431)
25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
68438-1 (40771025)
Endocrinology
46 (38004485)
pH of Serum or Plasma
2753-2 (3018418)
Calcium.ionized [Moles/volume] in Serum or Plasma
1995-0 (3021347)
Urology
34 (38004474)
Parathyrin.intact [Mass/volume] in Serum or Plasma
2731-8 (3000067)
Phosphate [Moles/volume] in Serum or Plasma
14879-1 (3003458)
Nephrology
39 (38004479)
Pharmacy visit
OMOP4822462 (581458)
pH of Specimen
17433-4 (3019225)
Calcium [Moles/volume] in Serum or Plasma
2000-8 (3015377)
Supplier / Service Provider
OMOP5117446 (33004)
Internal Medicine
11 (38004456)
Laboratory Visit
OMOP4822461 (32036)
Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
6768-6 (3035995)
Sodium [Moles/volume] in Serum or Plasma
2951-2 (3019550)
Albumin [Mass/volume] in Serum or Plasma
1751-7 (3024561)
Potassium [Moles/volume] in Serum or Plasma
2823-3 (3023103)
Cystoscopy
UKC02 (2001306005)
Creatinine [Moles/volume] in Serum or Plasma
14682-9 (3020564)
Case Management Agency
251B00000X (38004193)
Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M
62238-1 (40764999)
MCH [Entitic mass]
28539-5 (3035941)
Leukocytes [#/volume] in Blood
26464-8 (3010813)
Erythrocytes [#/volume] in Blood
26453-1 (3026361)
Hematocrit [Volume Fraction] of Blood by calculation
20570-8 (3009542)
MCV [Entitic mean volume] in Red Blood Cells
30428-7 (3024731)
Platelets [#/volume] in Blood
26515-7 (3007461)
Hemoglobin [Mass/volume] in Blood
718-7 (3000963)
MCHC [Entitic Mass/volume] in Red Blood Cells
28540-3 (3003338)
CBC panel - Blood by Automated count
58410-2 (40761511)
Erythrocyte [DistWidth] in Red Blood Cells
30385-9 (3002385)

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
120
139
18.48
106.45
3.9
3.9
60.70
76.23
ng/l
1.60
108
126
116
242
9.33
60.93
3.0
7.0
0.90
1.03
mmol/l
5.65
108
228
170
845
6.01
28.39
5.1
2.5
78.04
77.01
nmol/l
0.22
159
764
179
941
6.65
27.57
11.1
8.1
1.23
1.21
mmol/l
2.45
157
817
165
850
5.18
24.95
9.0
7.3
1.23
1.21
mmol/l
1.54
155
787
28
39
8.11
19.57
2.9
2.4
5.74
6.83
pmol/l
0.36
28
39
29
17
19.53
19.34
1.3
1.2
127.28
113.41
pmol/l
0.61
29
17
15
0
+∞
15.82
1.4
0.0
301.80
umol/24h
15
0
53
166
3.92
15.07
8.5
4.7
7.36
7.33
ph
0.44
41
115
21
11
20.99
14.56
2.1
1.2
161.00
185.33
mmol/24h
0.36
21
11
105
523
2.99
13.84
2.3
3.1
328.14
335.63
umol/l
0.39
95
460
112
581
2.96
13.65
5.8
4.6
7.40
7.40
ph
1.16
95
406
11
0
+∞
11.56
1.5
0.0
2.31
mmol/24h
11
0
11
0
+∞
11.56
1.2
0.0
27.83
mg/24h
11
0
114
658
2.58
10.45
3.6
3.3
2.35
2.35
mmol/l
0.12
101
596
72
338
2.71
10.02
2.2
3.7
0.83
0.82
mmol/l
0.49
66
323
26
67
4.28
9.45
1.8
4.3
154.33
299.06
mg/l
6
31
14
9
16.53
9.16
1.8
1.3
66.83
56.24
ng/l
14
9
35
121
3.26
8.33
1.7
3.2
0
0
188
1477
3.32
7.99
7.6
9.0
75.74
78.69
u/l
0.62
182
1403
37
143
2.92
7.26
1.7
3.7
68.31
66.88
g/l
0.81
32
134
75
421
2.21
6.64
3.2
2.7
3.05
4.40
e6/l
1.36
68
378
97
620
2.04
5.98
2.4
2.6
57.70
61.94
u/l
0.24
87
573
38
169
2.52
5.65
1.1
1.2
0
0
12
17
7.41
5.52
3.3
3.1
0
0
105
707
1.96
5.44
4.8
3.7
21.66
121.30
e6/l
1.15
78
483
95
620
1.96
5.38
4.1
3.1
84.13
37.48
e6/l
0.55
75
467
44
215
2.32
5.32
2.5
2.1
348.45
384.57
nmol/l
0.58
44
203
5
0
+∞
5.23
1.0
0.0
538.80
mg/24h
5
0
20
65
3.29
5.22
2.8
2.6
25.11
24.83
mmol/l
0.13
20
65
78
487
1.95
4.95
1.4
1.3
1.04
1.47
u/ml
0.35
23
134
30
127
2.59
4.92
3.9
3.7
7.43
7.42
ph
1.09
24
104
116
828
1.88
4.86
4.1
5.1
37.05
36.15
g/l
1.14
110
792
178
1481
2.23
4.61
5.6
4.4
14.89
14.65
pmol/l
0.65
167
1363
168
1374
2.05
4.46
3.1
3.6
43.61
49.24
u/l
0.57
157
1304
17
56
3.21
4.35
2.6
4.8
111.42
1.64
ratio
0.49
12
34
33
158
2.29
4.15
2.5
2.5
0.21
0.16
e6/l
0.27
33
151
59
353
1.93
4.15
4.0
2.8
582.12
541.93
mosm/kgh2o
0.94
51
305
98
690
1.78
4.08
3.4
3.5
8.16
7.99
mmol/l
0.14
82
593
10
19
5.47
3.87
1.5
1.1
0
0
102
735
1.74
3.86
2.3
2.1
0
0
198
1760
2.77
3.81
7.0
5.4
1.82
1.89
mu/l
0.40
185
1636
48
280
1.92
3.60
1.4
1.3
0
0
13
36
3.78
3.56
4.5
2.4
93.10
89.35
%
1.33
13
36
62
396
1.80
3.50
1.5
1.3
18.10
27.09
iu/ml
0.49
17
122
74
498
1.74
3.49
4.9
2.9
0
0
204
1881
3.00
3.47
15.7
15.2
20.59
22.86
mg/l
0.41
165
1517
11
27
4.24
3.45
1.8
1.3
39.05
34.28
ng/l
0.09
11
27
78
535
1.72
3.43
4.2
3.0
0.17
0.47
e6/l
1.37
59
382
50
303
1.85
3.33
1.5
1.3
424.00
482.46
titre
10
65
68
453
1.74
3.30
1.5
1.4
2.00
2.39
g/l
1.42
38
281
7
11
6.54
3.21
1.9
3.3
358.14
826.82
u/ml
7
11
201
1830
2.75
3.10
6.1
5.1
5.86
5.91
mmol/l
0.30
188
1704
139
1129
1.67
3.09
5.1
5.3
6.63
6.64
mmol/l
0.02
131
1073
8
16
5.15
3.08
4.3
5.1
0
0
15
57
2.76
3.03
1.9
2.1
0
0
96
715
1.62
3.00
4.3
3.4
15.29
118.05
ng/l
0.66
72
482
5
6
8.49
2.76
1.0
1.0
104.80
51.00
nmol/24h
5
6
55
363
1.69
2.71
1.5
1.3
13.46
7.42
u/ml
0.25
20
143
104
804
1.57
2.70
4.3
3.5
6.16
6.18
ph
0.09
64
462
119
949
1.58
2.70
4.9
6.9
28.95
28.03
%
0.35
112
913
88
655
1.59
2.69
4.8
6.6
0
0
19
87
2.30
2.66
1.4
1.2
1.94
0
5
124
1001
1.57
2.65
5.3
3.8
0.00
0.00
estimate
-0.00
27
200
116
926
1.55
2.57
4.9
6.8
3.12
2.83
%
0.76
109
877
116
926
1.55
2.57
5.1
6.9
0.73
0.71
%
0.09
106
873
5
7
7.28
2.56
1.0
2.4
0.66
0.60
mmol/l
5
7
42
262
1.75
2.52
2.1
2.5
98.28
104.38
ug/g
0.04
32
209
85
639
1.55
2.44
3.5
3.6
32.90
50.93
mg/l
0.60
54
404
23
119
2.05
2.41
3.4
4.0
4.58
4.63
pmol/l
0.06
18
104
125
1025
1.53
2.38
5.3
3.9
0.11
0.00
estimate
0.49
27
187
104
820
1.52
2.38
2.1
2.0
104.50
98.24
pmol/l
0.49
52
392
23
121
2.01
2.31
1.4
1.3
0
0
115
931
1.51
2.30
5.2
6.9
8.97
8.70
%
0.57
108
887
116
941
1.51
2.30
4.9
6.8
55.14
57.31
%
1.16
109
903
8
23
3.57
2.29
1.5
1.1
0
0
123
1014
1.50
2.23
5.4
3.8
0.00
0.00
estimate
-0.00
26
200
5
9
5.66
2.22
2.4
1.9
0
0
86
660
1.51
2.20
4.3
4.2
3.72
9.21
mg/mmol
1.60
56
406
109
883
1.48
2.11
3.4
2.9
112.68
123.56
ug/l
0.26
99
834
107
866
1.47
2.07
7.7
9.5
1.10
1.16
inr
0.81
84
705
25
143
1.85
1.99
1.4
1.2
32.03
122.51
u/ml
3.13
12
51
74
560
1.49
1.99
4.7
3.2
2.13
0.00
estimate
0.50
24
161
40
263
1.64
1.98
2.5
3.4
3.81
6.77
e9/l
1.27
32
236
73
553
1.49
1.95
3.9
3.0
0.25
0
8
7
22
3.25
1.89
1.1
1.1
0
0
121
1017
1.44
1.85
5.2
6.9
0.04
0.04
e9/l
0.25
107
877
124
1050
1.43
1.80
5.4
7.2
0.20
0.19
e9/l
0.27
111
920
120
1011
1.43
1.78
5.3
6.9
0.56
0.57
e9/l
0.21
108
874
27
166
1.72
1.72
7.1
9.5
0
0
17
90
1.97
1.70
3.4
4.1
0
0
10
40
2.57
1.69
5.1
2.4
0
0
94
766
1.41
1.65
5.2
3.7
0.96
0.00
estimate
0.49
26
167
24
145
1.74
1.62
3.3
2.3
6.00
6.17
ph
0.39
17
89
208
2004
2.61
1.56
11.8
12.7
29.04
27.72
u/l
0.49
203
1959
38
263
1.54
1.53
1.5
1.6
1263.89
1225.82
nmol/l
0.09
26
192
120
1030
1.38
1.50
5.4
6.9
1.86
2.02
e9/l
0.54
111
911
28
181
1.63
1.49
2.5
2.2
0.00
0.00
estimate
6
42
9
38
2.43
1.47
1.2
1.2
0
0
42
300
1.50
1.47
3.7
2.8
1.17
2.61
e6/l
1.01
21
143
5
16
3.17
1.44
1.6
2.0
0
0
12
61
2.02
1.35
1.5
1.5
266.46
287.51
ug/g
7
36
49
368
1.43
1.33
1.7
1.7
469.72
460.77
pmol/l
0.06
40
322
191
1799
1.60
1.27
7.6
6.4
38.90
39.18
mmol/mol
0.19
179
1705
192
1811
1.61
1.26
5.3
4.4
1.40
1.31
mmol/l
0.95
173
1676
203
1943
1.95
1.26
16.2
13.3
0
0
121
1058
1.33
1.25
4.4
7.4
10.12
10.97
umol/l
0.79
110
1009
8
36
2.27
1.25
1.3
1.8
0
0
57
447
1.38
1.21
1.9
1.7
1.55
1.31
mg/l
0.14
37
347
14
79
1.83
1.20
4.1
6.5
0.84
0.89
%
0.22
14
70
127
1123
1.32
1.19
7.9
11.4
3.66
4.04
e9/l
1.65
113
981
99
848
1.31
1.16
1.9
2.0
1.49
1.40
mmol/l
0.32
78
711
27
188
1.50
1.08
3.0
4.0
7.39
7.39
ph
0.07
15
109
31
223
1.46
1.06
1.5
1.4
0
0
103
900
1.28
1.00
2.9
2.8
estimate
0
0
0
32
0.00
0.96
0.0
2.1
0
0
199
1912
1.62
0.95
6.8
6.0
2.87
2.77
mmol/l
0.85
185
1787
12
70
1.76
0.94
1.0
1.1
1.49
1.55
g/l
0.30
12
70
18
118
1.57
0.94
1.4
1.8
0
0
197
1893
1.54
0.88
6.2
5.3
4.75
4.70
mmol/l
0.28
182
1774
6
30
2.03
0.87
1.2
1.2
0
0
57
469
1.29
0.87
2.4
2.0
2.57
2.96
mg/l
0.67
47
412
12
72
1.71
0.87
1.0
1.1
0.95
0.91
g/l
0.28
12
72
35
268
1.37
0.87
1.4
1.5
0
0
30
224
1.39
0.86
1.3
1.5
0
0
73
621
1.27
0.86
2.5
2.4
0
0
8
45
1.81
0.85
2.3
1.9
144.25
130.00
g/l
8
34
6
31
1.96
0.85
1.2
1.3
0
0
55
452
1.29
0.85
5.0
3.9
1.02
1.02
kg/l
0.91
41
305
196
1884
1.51
0.84
6.4
5.2
1.43
1.46
mmol/l
0.71
181
1754
18
257
0.67
0.83
1.5
1.6
0
0
15
98
1.57
0.81
1.4
1.3
0
0
8
48
1.69
0.79
1.0
1.5
0
0
14
91
1.58
0.77
4.2
6.0
1.56
1.63
%
0.21
14
82
14
91
1.58
0.77
2.8
2.2
0
0
5
25
2.02
0.73
2.2
2.8
0
0
5
25
2.02
0.73
1.2
1.0
0
0
34
268
1.32
0.71
6.9
8.0
105.24
104.05
mmol/l
0.73
34
268
15
102
1.51
0.69
2.7
2.3
0.00
0.00
estimate
6
33
73
642
1.21
0.62
5.4
4.9
1.87
2.53
ug/l
0.56
68
576
5
30
1.68
0.62
1.2
3.0
4.36
4.83
e9/l
5
30
62
537
1.22
0.61
1.7
1.6
24.09
21.40
nmol/l
0.46
52
448
19
141
1.38
0.59
4.5
3.7
0
0
6
35
1.73
0.58
1.0
1.2
0
0
64
562
1.20
0.55
5.5
3.8
0.00
0.01
estimate
0.50
26
189
6
39
1.55
0.53
1.0
1.1
0
0
7
45
1.57
0.49
4.6
7.9
105.14
105.03
mmol/l
7
39
7
45
1.57
0.49
4.6
7.9
11.29
10.97
mmol/l
7
39
0
15
0.00
0.41
0.0
1.5
937.57
0
7
0
15
0.00
0.41
0.0
1.2
0.33
0
8
0
16
0.00
0.41
0.0
2.8
9.73
0
11
0
16
0.00
0.41
0.0
1.4
2.41
0
8
12
89
1.37
0.39
2.7
1.8
0
0
13
169
0.75
0.38
1.5
1.4
0
0
9
67
1.36
0.38
1.0
1.1
0
0
27
226
1.22
0.38
1.9
1.6
0
0
31
358
0.84
0.34
1.7
1.9
0
0
43
381
1.16
0.34
3.1
3.0
0.68
0.75
ug/l
0.45
27
226
6
46
1.31
0.33
1.2
2.9
60.33
58.12
%
6
46
86
804
1.12
0.30
2.9
3.1
0
0
14
112
1.27
0.29
3.4
5.7
0
0
28
245
1.16
0.26
1.5
1.3
0
0
42
380
1.13
0.25
2.8
3.7
157.60
440.42
ng/l
0.86
29
280
51
468
1.12
0.25
4.4
5.9
0
0
23
201
1.16
0.22
1.9
4.6
4.83
28.94
ug/l
0.60
16
168
20
173
1.17
0.22
3.7
5.7
0.20
0.57
%
5
60
0
11
0.00
0.21
0.0
2.9
0.73
0
11
0
10
0.00
0.21
0.0
3.1
529.20
0
5
0
12
0.00
0.21
0.0
2.3
0
0
0
12
0.00
0.21
0.0
1.6
0
0
0
12
0.00
0.21
0.0
1.0
0
0
14
117
1.21
0.21
8.7
9.7
17.31
16.25
%
0.62
14
110
0
13
0.00
0.21
0.0
1.0
0
0
0
13
0.00
0.21
0.0
2.8
700.17
0
6
0
14
0.00
0.20
0.0
1.6
68440.00
0
5
6
49
1.23
0.20
1.2
1.2
3.43
3.79
mmol/l
6
43
7
62
1.13
0.17
1.1
1.1
0
0
20
177
1.14
0.17
3.7
6.3
0.00
0.08
%
5
49
5
70
0.71
0.17
29.0
10.3
0
0
6
79
0.75
0.16
1.0
1.5
0
0
14
161
0.86
0.15
1.4
1.5
0
0
9
82
1.10
0.15
1.3
1.3
0
0
52
548
0.93
0.13
1.4
1.4
0
0
9
108
0.83
0.13
4.8
3.1
0.71
0.59
%
9
108
58
607
0.94
0.12
4.8
6.7
0
0
11
95
1.17
0.12
1.1
1.1
0
0
27
291
0.92
0.11
1.6
2.1
0
0
14
124
1.14
0.11
4.6
8.4
25.31
24.66
mmol/l
0.25
14
116
15
166
0.90
0.10
1.3
1.7
0
0
161
1632
0.94
0.10
19.8
19.5
334.83
332.81
g/l
2.14
161
1626
5
44
1.14
0.10
1.4
2.3
59.34
60.78
%
5
44
5
60
0.83
0.08
1.0
1.1
0
0
8
91
0.87
0.07
6.6
4.9
36.84
36.94
°c
8
91
52
509
1.03
0.03
4.7
4.5
0
0
20
201
0.99
0.00
10.7
9.7
95.00
96.03
%
0.26
20
194
21
209
1.01
0.00
1.2
1.5
0
0
22
219
1.01
0.00
10.0
9.3
5.36
5.20
kpa
0.23
22
209
22
219
1.01
0.00
10.0
9.4
7.39
7.41
ph
0.57
15
128
22
219
1.01
0.00
10.0
9.3
10.92
12.34
kpa
1.28
22
210
88
885
0.99
0.00
11.7
11.5
0.00
0.00
e9/l
0.58
73
719
20
195
1.03
0.00
9.9
9.7
127.10
123.61
g/l
0.31
20
189
13
128
1.02
0.00
1.2
1.1
0
0
0
6
0.00
0.00
0.0
1.0
0.02
0
6
0
6
0.00
0.00
0.0
6.8
0
0
0
6
0.00
0.00
0.0
5.5
12.56
0
6
0
6
0.00
0.00
0.0
1.0
53.33
0
6
0
6
0.00
0.00
0.0
6.0
24.83
0
6
0
6
0.00
0.00
0.0
1.0
0
0
8
83
0.96
-0.00
1.0
1.5
0
0
7
73
0.96
-0.00
1.1
1.3
0
0
0
8
0.00
-0.00
0.0
1.3
28.50
0
8
0
9
0.00
-0.00
0.0
1.6
0
0
0
5
0.00
-0.00
0.0
2.2
0
0
8
83
0.96
-0.00
1.0
1.5
0
0
8
81
0.99
-0.00
1.0
1.5
0
0
0
5
0.00
-0.00
0.0
1.0
0
0
0
5
0.00
-0.00
0.0
1.2
0
0
0
5
0.00
-0.00
0.0
1.4
2.14
0
5
0
7
0.00
-0.00
0.0
1.4
29.57
0
7
7
70
1.00
-0.00
2.3
2.3
81.00
287.90
ug/l
7
64
5
52
0.96
-0.00
1.6
1.3
0
0
0
8
0.00
-0.00
0.0
5.4
0
0
0
5
0.00
-0.00
0.0
1.0
0
0
8
83
0.96
-0.00
1.0
1.5
0
0
30
300
1.00
-0.00
1.4
1.6
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: E4_IDIOPATHIC_HYPERCALCIURIA – Idiopathic hypercalciuria

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).