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Contracture of muscle

DOID EFO Endpoint Browser PheWeb

M13_MUSCONTRAC

muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.

Suggest a new description

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M62.4
  • Cause of death: ICD-10 — M62.4

2 out of 7 registries used, show all original rules.

182

4. Check minimum number of events

None

182

5. Include endpoints

None

182

6. Filter based on genotype QC (FinnGen only)

170

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M62
Name in latin
Contractura musculi

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1175 667 502
Only index persons 1106 642 464
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 46.18 48.13 43.55
Only index persons 46.00 48.18 42.98

-FinnGen-

Key figures

All Female Male
Number of individuals 170 118 52
Unadjusted period prevalence (%) 0.04 0.04 0.02
Median age at first event (years) 55.93 53.35 61.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
172
Matched controls
1720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M62.4
ICD-10 Finland
Contracture of muscle
+∞
248.8
172
*
M79.6
ICD-10 Finland
Pain in limb
5.6
27.9
109
405
M25.5
ICD-10 Finland
Pain in joint
4.4
20.8
86
318
N03AX16
ATC
[U] pregabalin
3.6
12.9
55
198
L08
ICPC
Shoulder symptom/complaint
3.6
12.1
49
170
M19.0
ICD-10 Finland
Primary arthrosis of other joints
5.2
11.6
26
57
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.1
11.4
66
284
M01AH05
ATC
etoricoxib; oral
3.2
11.3
123
750
L03
ICPC
Low back symptom/complaint
3.1
10.9
64
277
M76.6
ICD-10 Finland
Achilles tendinitis
8.4
10.6
23
31
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.5
10.6
43
148
R4120
NOMESCO Finland
Occupational therapy
5.6
10.3
21
42
A02BC02
ATC
pantoprazole; systemic
3.1
9.9
130
853
Z3226
NOMESCO Finland
Physiotherapist
3.4
9.8
43
155
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.8
9.8
81
417
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
4.4
9.5
26
67
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.6
9.5
24
58
M54.5
ICD-10 Finland
Low back pain
2.8
9.5
71
346
G44.2
ICD-10 Finland
Tension-type headache
3.6
9.4
36
119
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
25.6
9.0
12
5
N02AX02
ATC
tramadol; systemic, rectal
2.7
9.0
78
407
N02AJ06
ATC
codeine and paracetamol; systemic
2.6
8.9
88
490
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
8.9
84
458
TQW40
NOMESCO Finland
Remowal of suture of skin
5.0
8.8
20
44
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
5.2
8.8
19
40
WX320
NOMESCO Finland
Spinalanesthesy
2.9
8.7
53
230
M54.4
ICD-10 Finland
Lumbago with sciatica
3.3
8.7
38
136
M03BX02
ATC
tizanidine; oral
2.8
8.7
122
802
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.8
8.5
29
88
M03BC51
ATC
orphenadrine, combinations; systemic
2.7
8.5
62
296
WX702
NOMESCO Finland
Supraglottic ventilation device
5.0
8.3
19
42
M79.1
ICD-10 Finland
Myalgia
3.3
8.3
36
128
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
8.3
38
140
H93.1
ICD-10 Finland
Tinnitus
4.4
8.2
22
56
M77.4
ICD-10 Finland
Metatarsalgia
6.7
8.1
20
33
R20.2
ICD-10 Finland
Paraesthesia of skin
5.0
8.1
18
39
X59
ICD-10 Finland
Exposure to unspecified factor
3.1
8.0
39
149
N06AX21
ATC
duloxetine; oral
3.7
7.9
27
82
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.5
7.8
20
49
M20.1
ICD-10 Finland
Hallux valgus (acquired)
3.8
7.6
25
74
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
7.3
51
235
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.1
7.2
34
127
L17
ICPC
Foot/toe symptom/complaint
2.5
7.1
62
319
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
11.6
6.9
12
11
L01
ICPC
Neck symptom/complaint
2.9
6.8
37
149
A02BC01
ATC
omeprazole; systemic
2.5
6.8
55
272
TLC00
NOMESCO Finland
Insertion of intrauterine device
4.1
6.7
19
50
N03AX12
ATC
[U] gabapentin; oral
3.0
6.7
32
120
X58
ICD-10 Finland
Exposure to other specified factors
3.0
6.7
33
126
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.3
6.6
18
46
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.7
6.5
22
66
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.9
6.5
34
134
Z2221
NOMESCO Finland
Medical doctor
2.4
6.4
59
309
WX002
NOMESCO Finland
Sedation and analgesia
2.7
6.3
40
175
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
+∞
6.3
6
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.6
6.3
41
182
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
6.3
51
252
U07
ICPC
Urine symptom/complaint other
3.7
6.2
21
63
R03AC02
ATC
salbutamol; inhalant
2.3
6.2
109
743
R4110
NOMESCO Finland
Physiotherapy
2.4
6.2
57
298
N02BE01
ATC
paracetamol; systemic, rectal
4.4
6.1
161
1325
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.3
6.0
62
339

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
54
233
2.92
9.00
2.7
2.6
4.10
2.91
e6/l
0.27
31
113
27
75
4.08
8.97
1.3
1.3
—
29.40
—
0
5
135
942
3.01
8.46
6.3
3.9
—
2692.69
—
0
13
53
246
2.67
7.55
3.5
3.2
194.00
406.04
ng/l
0.46
40
182
97
597
2.43
7.53
2.4
1.9
105.38
96.98
pmol/l
0.77
49
307
34
126
3.12
7.29
1.2
1.1
—
—
—
0
0
57
285
2.50
6.89
1.8
1.5
1.04
1.48
mg/l
0.58
49
224
61
320
2.40
6.60
2.2
2.8
321.37
338.49
umol/l
0.60
51
281
103
676
2.31
6.58
5.6
5.8
55.87
56.31
%
0.16
97
651
19
51
4.06
6.57
2.6
2.5
—
—
—
0
0
78
463
2.25
6.27
4.7
5.5
—
—
—
0
0
64
351
2.31
6.20
1.5
1.3
0.83
1.82
u/ml
—
8
95
103
689
2.23
6.12
5.7
5.9
29.37
28.88
%
0.18
97
660
67
377
2.27
6.09
3.1
2.7
—
—
estimate
—
0
0
76
454
2.21
5.94
2.9
2.8
—
0.00
—
0
5
110
765
2.21
5.81
5.7
6.4
0.22
0.19
e9/l
0.97
100
678
107
740
2.18
5.68
5.3
5.8
0.04
0.04
e9/l
0.31
91
643
146
1152
2.77
5.67
5.7
4.1
14.19
14.72
pmol/l
1.98
139
1057
108
754
2.16
5.54
5.6
5.8
1.88
1.99
e9/l
0.36
99
678
106
737
2.14
5.47
5.3
5.8
0.59
0.57
e9/l
0.36
91
642
99
671
2.12
5.46
6.0
5.8
0.61
0.69
%
0.86
93
627
43
209
2.41
5.40
1.3
1.2
6.63
16.25
u/ml
0.66
12
78
86
557
2.09
5.30
4.3
3.4
13.82
97.14
e6/l
3.16
62
382
58
325
2.18
5.20
1.4
1.5
2.02
2.29
g/l
0.71
31
197
31
131
2.67
5.18
1.6
1.9
31.15
34.00
u/l
0.39
26
109
64
374
2.13
5.15
2.5
1.8
2.51
2.96
mg/l
0.78
54
328
98
675
2.05
5.02
5.8
5.8
2.93
2.90
%
0.03
92
637
71
435
2.08
5.02
3.2
2.6
—
—
—
0
0
98
677
2.04
4.96
6.0
5.9
9.07
8.83
%
0.36
91
640
65
392
2.06
4.75
2.0
1.5
19.41
20.79
nmol/l
0.37
55
336
16
48
3.57
4.73
1.8
1.7
—
—
—
0
0
37
179
2.36
4.65
1.5
1.3
231.11
468.18
titre
—
9
44
46
245
2.20
4.62
1.5
1.2
9.33
37.73
iu/ml
2.86
15
80
67
412
2.03
4.62
3.2
2.7
0.20
0.46
e6/l
1.18
50
295
160
1368
3.43
4.53
7.1
5.1
1.84
1.88
mu/l
0.17
152
1266
165
1473
3.95
4.48
20.8
12.8
25.12
24.81
mg/l
0.04
131
1162
91
632
1.93
4.34
2.4
2.0
—
—
—
0
0
88
607
1.92
4.26
6.4
5.6
1.23
1.21
mmol/l
0.93
82
564
113
852
1.95
4.13
8.0
10.2
4.10
3.99
e9/l
0.25
96
740
95
678
1.90
4.09
7.4
6.3
1.23
1.21
mmol/l
1.68
85
593
72
473
1.90
3.98
3.5
2.8
13.32
61.50
e6/l
2.38
55
359
104
774
1.87
3.84
5.3
6.4
9.69
11.10
umol/l
1.50
99
745
25
111
2.47
3.77
1.2
1.2
202.00
144.89
u/ml
—
8
47
67
437
1.87
3.74
2.2
2.3
55.74
67.36
u/l
0.56
61
413
84
594
1.81
3.58
1.7
1.8
1.29
1.32
mmol/l
0.13
76
502
8
14
5.93
3.38
1.3
1.1
—
—
—
0
0
22
97
2.45
3.36
1.2
3.7
62.73
66.83
g/l
1.63
17
90
18
72
2.68
3.33
1.5
1.2
—
—
—
0
0
134
1111
1.93
3.21
7.8
7.7
73.43
81.87
u/l
1.45
129
1057
50
310
1.86
3.20
2.4
2.4
3.62
8.10
e6/l
1.03
43
280
84
609
1.74
3.18
20.1
10.3
1.22
1.19
inr
0.20
65
501
12
35
3.61
3.18
1.2
1.8
—
—
—
0
0
11
30
3.84
3.15
1.5
2.1
—
—
—
0
0
93
696
1.73
3.12
2.9
2.5
—
—
estimate
—
0
0
154
1350
2.34
3.05
6.8
5.6
38.43
38.71
mmol/mol
0.17
148
1272
12
37
3.41
3.00
1.2
1.1
—
—
—
0
0
44
267
1.87
2.99
2.3
2.9
500.79
547.34
mosm/kgh2o
0.74
38
231
12
39
3.23
2.83
1.5
1.1
—
—
—
0
0
70
501
1.67
2.66
3.6
3.2
2.36
2.36
mmol/l
0.13
63
459
34
198
1.89
2.61
1.6
1.5
835.01
1231.08
nmol/l
2.37
25
145
107
857
1.66
2.59
4.7
4.2
6.66
6.55
mmol/l
0.17
102
807
99
778
1.64
2.58
3.5
3.4
118.92
0.00
estimate
0.47
12
159
98
769
1.64
2.57
3.6
3.4
0.00
0.00
estimate
-0.00
11
158
60
418
1.67
2.50
4.4
4.1
7.39
7.40
ph
0.97
40
287
83
628
1.62
2.50
3.1
3.2
6.33
6.20
ph
0.39
36
362
6
12
5.14
2.42
1.2
1.4
—
—
—
0
0
17
78
2.31
2.40
1.3
3.6
—
—
—
0
0
17
78
2.31
2.40
5.3
2.7
4.36
4.49
pmol/l
0.33
17
70
99
790
1.60
2.34
3.7
3.4
0.00
0.02
estimate
—
9
142
53
364
1.66
2.31
4.6
3.7
—
—
—
0
0
155
1397
2.11
2.28
4.1
3.8
1.23
1.23
mmol/l
0.02
148
1293
5
9
5.68
2.23
1.0
1.0
—
—
—
0
0
5
9
5.68
2.23
1.0
1.0
—
—
—
0
0
5
9
5.68
2.23
1.0
1.0
—
—
—
0
0
30
181
1.80
2.06
1.3
1.3
—
—
—
0
0
20
105
2.02
2.06
2.4
1.9
6.45
6.19
ph
0.60
11
72
30
182
1.79
2.02
1.3
1.2
—
—
—
0
0
154
1399
1.96
1.99
5.2
4.6
5.75
5.82
mmol/l
0.40
146
1291
26
152
1.84
1.97
4.9
6.3
0.78
1.13
mmol/l
0.18
20
129
61
449
1.56
1.96
6.6
6.8
—
—
—
0
0
66
495
1.54
1.95
2.5
2.0
—
—
—
0
0
5
11
4.65
1.95
2.0
2.5
—
—
—
0
0
18
93
2.04
1.93
2.4
3.2
—
—
—
0
0
12
52
2.41
1.92
1.1
1.1
—
—
—
0
0
145
1298
1.75
1.91
26.6
17.2
332.46
332.06
g/l
0.20
145
1291
26
154
1.81
1.89
5.2
6.3
7.45
7.42
ph
—
7
89
8
28
2.95
1.88
1.3
1.1
—
—
—
0
0
8
28
2.95
1.88
1.3
1.1
—
—
—
0
0
163
1527
2.29
1.87
16.8
11.7
—
—
—
0
0
22
126
1.86
1.78
5.7
5.3
1.36
1.32
mmol/l
0.07
22
126
19
104
1.93
1.75
5.0
3.9
7.39
7.34
ph
1.40
14
76
45
317
1.57
1.73
1.9
2.1
—
—
—
0
0
157
1452
1.93
1.66
5.1
4.5
1.54
1.51
mmol/l
0.34
149
1351
159
1478
2.00
1.63
6.3
5.2
2.76
2.77
mmol/l
0.05
152
1381
12
57
2.19
1.59
2.3
1.6
—
—
—
0
0
157
1462
1.85
1.47
5.2
4.6
4.78
4.72
mmol/l
0.32
151
1371
6
22
2.79
1.44
1.0
1.2
—
—
—
0
0
41
295
1.51
1.43
2.2
2.6
2.44
2.45
mmol/l
0.08
33
267
12
60
2.08
1.42
1.0
1.2
—
—
—
0
0
29
193
1.60
1.41
2.7
2.3
43.17
134.08
ug/g
2.38
24
156
9
41
2.26
1.39
1.2
1.2
—
—
—
0
0
6
24
2.55
1.31
1.2
1.5
—
—
—
0
0
8
34
2.42
1.31
1.1
1.1
—
—
—
0
0
11
55
2.07
1.30
1.3
1.7
1.32
1.55
g/l
0.35
11
48
10
49
2.11
1.24
1.1
1.2
—
68.33
—
0
6
24
158
1.60
1.23
1.8
1.8
—
—
—
0
0
29
200
1.54
1.22
2.9
1.8
—
—
—
0
0
11
57
1.99
1.20
5.6
3.0
—
—
—
0
0
24
162
1.56
1.12
1.5
1.4
—
—
—
0
0
20
130
1.61
1.08
6.8
5.5
—
—
—
0
0
38
285
1.43
1.08
1.5
1.7
—
—
—
0
0
53
423
1.37
1.05
3.7
3.1
61.37
46.20
mg/l
0.20
39
271
58
470
1.35
1.04
3.4
3.0
8.17
7.58
mmol/l
0.44
48
399
5
22
2.31
1.04
1.2
1.3
—
—
—
0
0
26
183
1.50
1.01
1.7
1.6
—
—
—
0
0
9
49
1.88
1.00
4.9
9.9
—
—
—
0
0
7
36
1.98
0.98
2.1
1.1
—
—
—
0
0
0
32
0.00
0.96
0.0
2.4
—
7.41
—
0
32
7
37
1.93
0.95
1.3
1.2
—
—
—
0
0
13
78
1.72
0.94
6.5
5.3
25.38
25.19
mmol/l
0.07
13
78
22
152
1.51
0.94
3.7
1.5
—
—
—
0
0
25
179
1.46
0.90
1.2
1.3
—
—
—
0
0
14
88
1.64
0.87
1.2
1.1
—
—
—
0
0
14
88
1.64
0.87
1.6
1.8
—
—
—
0
0
78
680
1.27
0.79
7.1
9.8
0.00
0.00
e9/l
0.25
56
559
0
26
0.00
0.79
0.0
3.4
—
3.95
—
0
26
0
26
0.00
0.79
0.0
3.4
—
1.19
—
0
26
0
26
0.00
0.79
0.0
3.4
—
105.19
—
0
26
13
84
1.59
0.74
5.8
2.3
23.73
24.32
mmol/l
0.25
13
84
16
111
1.49
0.69
1.4
2.9
63.30
69.64
e9/l
—
8
81
7
43
1.65
0.67
1.4
1.3
—
—
—
0
0
33
406
0.77
0.65
3.8
3.2
0.00
0.02
estimate
0.74
11
145
15
104
1.48
0.65
1.3
1.3
—
—
—
0
0
6
103
0.57
0.64
3.7
2.9
—
—
—
0
0
24
183
1.36
0.64
3.6
3.0
0.92
0.76
ug/l
0.34
17
126
0
20
0.00
0.61
0.0
2.5
—
4.95
—
0
20
0
20
0.00
0.61
0.0
2.5
—
8.64
—
0
20
0
20
0.00
0.61
0.0
2.5
—
2.72
—
0
11
8
52
1.56
0.60
1.1
1.3
20.50
20.22
s
—
8
46
51
436
1.24
0.59
4.1
3.9
15.52
7.50
mg/mmol
0.41
34
270
6
35
1.74
0.58
1.0
2.8
9.83
8.51
kpa
—
6
35
13
92
1.45
0.52
6.0
7.2
94.25
93.38
%
0.31
13
92
40
338
1.24
0.52
2.6
5.0
—
—
—
0
0
7
45
1.58
0.49
1.3
1.4
—
—
—
0
0
7
49
1.45
0.46
1.1
1.1
1.47
1.62
g/l
—
7
49
7
49
1.45
0.46
1.1
1.1
0.78
0.89
g/l
—
7
49
57
507
1.19
0.44
4.0
3.6
166.49
36.47
ng/l
0.46
28
356
0
15
0.00
0.41
0.0
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
3.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
117.50
—
0
16
14
106
1.35
0.40
8.6
5.1
10.39
9.40
mmol/l
0.15
14
101
16
124
1.32
0.40
1.7
1.5
—
—
—
0
0
5
79
0.62
0.36
1.2
1.7
—
—
—
0
0
20
165
1.24
0.33
1.9
4.9
2.44
65.06
ug/l
0.79
14
134
17
140
1.24
0.29
1.4
1.4
—
—
—
0
0
6
83
0.71
0.24
4.8
2.8
0.52
0.63
%
—
6
83
6
85
0.70
0.24
4.8
2.8
1.02
1.15
%
—
6
85
51
471
1.12
0.23
1.5
1.5
—
—
—
0
0
5
42
1.20
0.21
1.0
2.4
24.32
24.81
mmol/l
—
5
42
0
11
0.00
0.21
0.0
1.2
—
147.68
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
6.6
—
—
—
0
0
0
10
0.00
0.21
0.0
9.2
—
0.70
—
0
10
0
13
0.00
0.21
0.0
2.4
—
—
—
0
0
0
14
0.00
0.20
0.0
3.2
—
90.48
—
0
14
59
627
0.91
0.20
3.0
2.9
—
—
—
0
0
18
156
1.17
0.19
4.8
2.8
7.36
7.39
ph
1.22
11
97
16
184
0.86
0.18
1.1
1.3
—
—
—
0
0
6
75
0.79
0.16
1.2
1.6
—
—
—
0
0
6
78
0.76
0.16
1.2
1.7
—
—
—
0
0
6
79
0.75
0.16
1.2
1.7
—
—
—
0
0
6
79
0.75
0.16
1.2
1.7
—
—
—
0
0
9
79
1.15
0.15
2.1
4.4
—
—
—
0
0
22
199
1.12
0.14
1.5
1.8
—
—
—
0
0
36
337
1.09
0.13
3.3
3.2
1.02
1.02
kg/l
0.21
24
217
41
434
0.93
0.12
2.9
2.8
0.00
0.00
estimate
—
9
120
15
167
0.89
0.11
1.2
1.4
—
—
—
0
0
17
154
1.12
0.10
4.9
2.8
5.78
5.65
kpa
0.22
17
147
12
106
1.14
0.10
6.7
2.1
40.33
47.74
u/ml
0.11
12
100
13
137
0.94
0.01
4.0
2.9
4.87
4.50
kpa
0.27
13
131
58
586
0.98
0.00
3.3
3.2
0.00
0.03
estimate
—
8
130
20
198
1.01
0.00
1.8
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
1.13
—
0
8
0
8
0.00
0.00
0.0
1.6
—
7.16
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
1.3
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.4
—
8.86
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.4
—
1682.14
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
40.80
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.7
—
—
—
0
0
6
64
0.94
-0.00
3.0
4.3
36.77
36.98
°c
—
6
64
0
5
0.00
-0.00
0.0
2.0
—
18.62
—
0
5
5
53
0.94
-0.00
1.2
1.6
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint M13_MUSCONTRAC and mortality.

Females

Parameter HR [95% CI] p-value
M13_MUSCONTRAC 1.421 [0.96, 2.1] 0.078
Birth year 0.995 [0.99, 1.0] 0.284

During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 551 females with M13_MUSCONTRAC died.

Males

Parameter HR [95% CI] p-value
M13_MUSCONTRAC 1.473 [1.01, 2.14] 0.043
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 432 males with M13_MUSCONTRAC died.

Mortality risk

Mortality risk for people of age

years, who have M13_MUSCONTRAC.

N-year risk Females Males
1 0.125% 0.285%
5 0.741% 1.557%
10 2.007% 3.941%
15 3.94% 7.491%
20 7.177% 13.183%

Relationships between endpoints

↥

Index endpoint: M13_MUSCONTRAC – Contracture of muscle

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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