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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Traumatic cerebral oedema

ST19_TRAUMAT_CEREBRAL_OEDEMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S06.1
  • Cause of death: ICD-10 S06.1

2 out of 7 registries used, show all original rules.

135

4. Check minimum number of events

None

135

5. Include endpoints

None

135

6. Filter based on genotype QC (FinnGen only)

124

Control definitions (FinnGen only)

Control exclude
NEURODIS

Extra metadata

Level in the ICD hierarchy
4
Special
ST19_TRAUMCOEDMA
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S06
Name in latin
Oedema cerebri/encephali traumaticum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 124 49 75
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 49.56 46.72 51.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
127
Matched controls
1270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S06.1
ICD-10 Finland
Traumatic cerebral oedema
+∞
183.4
127
*
S06.0
ICD-10 Finland
Concussion
65.0
79.5
46
11
AA1AD
NOMESCO Finland
CT of head and brain
11.3
42.0
63
102
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
39.7
36
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
+∞
32.7
30
*
S06.2
ICD-10 Finland
Diffuse brain injury
+∞
28.2
26
*
W19
ICD-10 Finland
Unspecified fall
7.9
20.6
33
54
S06.3
ICD-10 Finland
Focal brain injury
+∞
19.2
18
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
18.1
17
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
4.7
16.6
62
215
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.1
14.4
37
94
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
+∞
13.8
13
*
N03AX14
ATC
levetiracetam; systemic
156.0
13.7
14
*
X59
ICD-10 Finland
Exposure to unspecified factor
4.5
13.0
40
117
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
+∞
11.6
11
*
R51.80
ICD-10 Finland
Headache
5.0
11.6
29
71
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
47.9
11.1
13
*
G47.3
ICD-10 Finland
Sleep apnoea
10.7
11.0
21
23
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
65.7
10.8
12
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
119.5
10.6
11
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
+∞
10.6
10
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
10.6
10
*
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
12.1
10.2
18
17
XA800
NOMESCO Finland
Neuropsychological investigation
28.7
10.0
13
5
N03AF02
ATC
oxcarbazepine; oral
32.8
9.6
12
*
AAF00
NOMESCO Finland
Ventriculostomy
+∞
9.5
9
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
10.3
9.4
18
20
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
8.0
9.0
20
29
TPH07
NOMESCO Finland
Cathetrisation of artery
5.1
8.4
19
42
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
+∞
8.4
8
*
S02.11
ICD-10 Finland
Fracture of base of skull, open
+∞
8.4
8
*
ZXD05
NOMESCO Finland
Urgent procedure
3.1
8.3
49
214
R56.8
ICD-10 Finland
Other and unspecified convulsions
11.9
8.0
14
13
N05AH04
ATC
quetiapine; oral
3.8
7.8
27
84
N06AB04
ATC
citalopram; systemic
3.6
7.7
30
101
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.2
7.4
22
61
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
+∞
7.4
7
*
S02.10
ICD-10 Finland
Fracture of base of skull, closed
+∞
7.4
7
*
S06.9
ICD-10 Finland
Intracranial injury, unspecified
+∞
7.4
7
*
S42.0
ICD-10 Finland
Fracture of clavicle
9.7
7.3
14
16
A06AD11
ATC
lactulose; oral
4.1
7.1
21
58
G44.2
ICD-10 Finland
Tension-type headache
6.8
7.1
17
28
JN5BD
NOMESCO Finland
Head and body CT examination for trauma
14.9
7.0
11
8
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
73.4
6.5
7
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.6
6.5
18
36
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.2
6.3
18
48
N03AX12
ATC
[U] gabapentin; oral
3.8
6.3
21
63
W00
ICD-10 Finland
Fall on same level involving ice and snow
3.9
6.3
20
58
WX723
NOMESCO Finland
CPAP therapy
+∞
6.3
6
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
6.3
6
*
S06.4
ICD-10 Finland
Epidural haemorrhage
+∞
6.3
6
*
Z2445
NOMESCO Finland
Psychologist
9.3
6.2
12
14
R5140
NOMESCO Finland
Monitoring the use of the aid
9.3
6.2
12
14
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
6.1
25
86

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
37
152
3.02
6.83
5.0
3.0
8.65
483.84
ng/l
1.22
26
116
24
86
3.21
5.51
12.6
6.3
4.94
5.21
kpa
0.71
24
80
24
86
3.21
5.51
12.6
6.3
14.55
12.85
kpa
0.44
24
81
24
86
3.21
5.51
12.7
6.3
7.42
7.41
ph
0.23
15
45
23
84
3.12
5.11
13.0
6.4
1.18
0.16
mmol/l
0.48
18
70
66
405
2.31
5.10
9.0
6.0
1.20
1.21
mmol/l
0.43
56
350
16
50
3.52
4.51
4.6
5.4
24.04
24.72
mmol/l
0.27
16
50
7
6
12.24
4.33
1.6
1.3
480.71
390.00
mg/l
—
7
6
61
397
2.03
3.73
9.1
14.9
1.25
1.30
inr
0.38
50
319
40
222
2.17
3.73
5.2
4.2
—
—
—
0
0
6
6
10.41
3.53
2.0
1.7
—
—
—
0
0
6
8
7.80
3.09
2.5
3.4
—
—
—
0
0
9
21
4.53
3.06
1.3
1.1
—
—
—
0
0
7
15
4.87
2.63
2.4
2.1
108.36
398.53
ug/l
—
7
15
6
11
5.66
2.57
1.2
1.1
—
—
—
0
0
6
11
5.66
2.57
1.2
1.1
—
—
—
0
0
6
11
5.66
2.57
1.2
1.1
—
—
—
0
0
6
11
5.66
2.57
1.2
1.1
—
—
—
0
0
85
673
1.80
2.45
4.6
3.6
14.64
14.71
pmol/l
0.09
78
602
12
47
2.72
2.35
17.0
2.9
—
—
—
0
0
19
94
2.20
2.30
3.4
3.2
7.36
7.37
ph
—
10
52
37
236
1.80
2.21
5.2
3.9
7.40
7.39
ph
0.17
32
163
18
91
2.14
2.07
1.7
1.3
—
—
—
0
0
19
100
2.06
1.98
1.2
1.2
—
—
—
0
0
100
854
1.80
1.97
5.5
4.3
1.88
1.87
mu/l
0.05
94
768
5
11
4.68
1.96
5.2
4.3
—
—
—
0
0
30
189
1.77
1.85
2.2
2.8
518.80
548.33
mosm/kgh2o
0.29
25
164
43
302
1.64
1.79
4.0
3.1
25.82
48.01
e6/l
0.69
36
219
16
82
2.09
1.79
6.5
7.0
—
—
—
0
0
44
315
1.61
1.68
5.5
5.7
—
—
—
0
0
35
242
1.62
1.53
3.7
2.7
—
—
—
0
0
6
21
2.95
1.52
4.3
3.1
7.42
7.42
ph
—
6
21
59
462
1.52
1.49
9.0
9.0
0.00
0.00
e9/l
0.50
47
375
20
119
1.81
1.48
1.9
1.9
—
—
—
0
0
7
28
2.58
1.47
1.3
3.6
—
—
—
0
0
29
193
1.65
1.47
1.8
1.7
—
—
—
0
0
37
262
1.58
1.46
4.1
3.1
0.16
0.28
e6/l
0.71
31
185
14
74
2.00
1.45
1.5
1.9
—
—
—
0
0
5
16
3.21
1.45
9.0
3.9
10.48
10.71
mg/l
—
5
16
5
16
3.21
1.45
4.8
3.8
8.40
8.29
kpa
—
5
16
5
16
3.21
1.45
4.8
3.8
2.10
1.94
mmol/l
—
5
9
5
16
3.21
1.45
4.8
3.8
5.44
4.88
kpa
—
5
16
24
153
1.70
1.42
4.2
2.8
9.38
2.46
e6/l
0.91
15
68
22
138
1.72
1.38
1.6
1.5
—
—
—
0
0
38
282
1.50
1.20
3.3
2.7
0.00
0.00
estimate
-0.00
12
79
10
50
2.09
1.20
1.5
2.8
—
—
—
0
0
55
442
1.43
1.15
8.9
5.7
2.65
2.84
%
0.38
50
416
34
250
1.49
1.12
4.1
3.0
—
—
estimate
—
0
0
82
713
1.42
1.08
8.3
7.4
81.16
81.46
u/l
0.02
77
663
13
75
1.82
1.07
1.5
1.8
—
—
—
0
0
13
75
1.82
1.07
1.5
1.8
—
—
—
0
0
44
345
1.42
1.04
4.6
3.5
29.51
286.54
e6/l
0.66
37
232
19
124
1.63
1.04
5.6
5.3
106.00
104.31
mmol/l
0.40
19
124
13
76
1.79
1.03
1.5
1.8
—
—
—
0
0
12
69
1.82
1.00
1.6
1.9
—
—
—
0
0
6
28
2.20
0.93
1.0
1.0
—
—
—
0
0
52
430
1.35
0.88
3.5
2.6
—
—
estimate
—
0
0
9
146
0.59
0.85
1.0
1.6
—
—
—
0
0
12
73
1.71
0.85
2.7
3.4
—
—
—
0
0
7
122
0.55
0.83
1.3
1.3
—
—
—
0
0
10
58
1.79
0.82
1.5
2.1
—
—
—
0
0
16
107
1.57
0.81
1.6
2.2
1.54
1.80
%
0.78
16
96
6
33
1.86
0.80
1.0
2.7
—
—
—
0
0
0
24
0.00
0.80
0.0
3.3
—
4.36
—
0
11
0
24
0.00
0.80
0.0
2.3
—
0.21
—
0
24
0
26
0.00
0.79
0.0
2.2
—
1.09
—
0
26
8
134
0.57
0.78
1.0
1.3
—
—
—
0
0
5
23
2.22
0.77
1.4
1.1
—
—
—
0
0
20
143
1.47
0.76
1.9
1.7
—
—
—
0
0
9
57
1.62
0.73
1.1
1.2
—
—
—
0
0
9
58
1.59
0.71
1.9
2.9
7.33
8.54
ug/l
—
9
53
5
26
1.96
0.71
1.6
2.1
—
—
—
0
0
28
219
1.36
0.66
1.3
1.2
0.84
1.45
u/ml
—
10
60
31
247
1.34
0.65
2.3
2.0
—
—
—
0
0
8
51
1.61
0.62
1.0
1.4
—
—
—
0
0
105
988
1.36
0.61
22.3
12.2
23.37
25.91
mg/l
0.32
88
774
56
488
1.26
0.60
4.6
3.2
0.14
0.00
estimate
0.47
14
105
55
479
1.26
0.59
4.6
3.2
0.00
0.00
estimate
-0.00
14
102
8
53
1.54
0.59
8.0
8.2
0.84
1.23
%
—
8
53
30
366
0.76
0.59
2.7
2.3
—
—
—
0
0
8
54
1.51
0.58
7.7
8.0
0.60
0.68
%
—
8
54
8
54
1.51
0.58
8.0
8.1
85.82
94.56
%
—
8
54
38
317
1.28
0.58
5.2
3.4
27.14
52.76
ng/l
0.93
27
213
28
226
1.31
0.54
5.4
3.0
1.02
1.02
kg/l
1.03
22
149
6
100
0.58
0.54
1.0
1.4
—
—
—
0
0
25
306
0.77
0.50
2.0
1.5
—
—
—
0
0
56
497
1.23
0.50
3.8
3.2
0.00
0.00
estimate
-0.00
14
99
15
111
1.40
0.49
2.2
2.8
316.22
210.48
ug/g
—
9
80
56
498
1.22
0.48
8.4
6.0
0.16
0.18
e9/l
0.94
51
434
34
286
1.26
0.48
3.6
3.4
—
—
—
0
0
45
392
1.23
0.47
4.0
2.9
6.11
6.25
ph
0.40
28
233
15
112
1.38
0.47
1.4
1.4
—
—
—
0
0
32
269
1.25
0.46
6.3
6.4
—
—
—
0
0
13
95
1.41
0.46
1.3
1.4
—
—
—
0
0
10
69
1.49
0.46
2.9
2.2
0.10
1.71
e6/l
—
10
63
43
374
1.23
0.46
4.7
3.1
0.00
0.05
estimate
0.68
12
83
5
31
1.64
0.43
1.6
1.3
—
—
—
0
0
8
57
1.43
0.43
1.5
1.4
0.86
1.06
g/l
—
8
51
0
15
0.00
0.41
0.0
3.9
—
4.89
—
0
15
0
15
0.00
0.41
0.0
4.1
—
62.20
—
0
15
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
8
112
0.70
0.39
2.3
1.9
—
—
—
0
0
5
77
0.64
0.37
1.2
1.5
—
—
—
0
0
30
258
1.21
0.35
3.2
3.1
28.30
74.84
mg/l
1.41
24
165
97
925
1.21
0.35
4.5
4.3
5.91
5.81
mmol/l
0.24
91
838
95
908
1.18
0.31
5.5
5.3
38.96
38.17
mmol/mol
0.36
90
845
54
496
1.15
0.30
8.3
5.7
1.77
1.75
e9/l
0.08
49
440
30
263
1.18
0.29
3.7
3.8
4.10
14.45
mg/mmol
1.45
23
159
60
557
1.15
0.28
11.0
9.6
4.09
4.15
e9/l
0.08
53
477
42
380
1.16
0.28
2.2
1.7
1.43
1.34
mmol/l
0.21
37
322
8
67
1.21
0.27
1.6
2.7
12.50
10.64
g/l
—
8
61
52
480
1.14
0.26
8.3
5.6
0.04
0.04
e9/l
0.32
46
408
5
41
1.23
0.22
1.2
3.0
9.40
6664.00
u/ml
—
5
36
0
11
0.00
0.21
0.0
2.5
—
2.18
—
0
6
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
30
270
1.15
0.21
3.3
3.4
0.00
0.02
estimate
0.49
12
93
0
12
0.00
0.21
0.0
1.0
—
2.00
—
0
5
0
12
0.00
0.21
0.0
2.5
—
—
—
0
0
9
110
0.80
0.21
5.4
3.5
3.72
4.21
e9/l
—
9
95
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
3.82
—
0
8
51
477
1.12
0.20
8.5
5.6
0.58
0.57
e9/l
0.15
45
406
106
1038
1.13
0.14
18.5
10.9
—
—
—
0
0
91
930
0.92
0.11
4.0
3.6
1.29
1.26
mmol/l
0.16
85
850
5
46
1.09
0.09
1.2
2.3
—
—
—
0
0
21
198
1.07
0.06
1.5
1.3
2.92
2.52
g/l
0.24
15
128
23
218
1.07
0.05
9.8
4.1
—
—
—
0
0
86
870
0.96
0.03
30.2
15.3
333.12
333.57
g/l
0.17
86
865
38
373
1.03
0.01
2.2
1.9
92.15
93.29
pmol/l
0.05
23
205
15
144
1.05
0.00
1.5
1.2
1.35
9.89
u/ml
—
8
50
40
401
1.00
0.00
3.3
2.8
—
—
—
0
0
30
305
0.98
0.00
3.1
2.2
—
—
—
0
0
11
108
1.02
0.00
1.2
1.4
—
—
—
0
0
17
165
1.03
0.00
1.4
1.3
35.84
26.78
iu/ml
—
7
44
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
15.20
—
0
5
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
43.60
—
0
5
0
5
0.00
-0.00
0.0
2.8
—
0.39
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
111.60
—
0
5
0
6
0.00
-0.00
0.0
2.5
—
15.92
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
11.2
—
5.14
—
0
5
0
7
0.00
-0.00
0.0
3.4
—
1.00
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
106.89
—
0
9
0
8
0.00
-0.00
0.0
1.9
—
1.22
—
0
8
0
9
0.00
-0.00
0.0
1.1
—
193.84
—
0
9
0
5
0.00
-0.00
0.0
6.0
—
8.80
—
0
5
0
7
0.00
-0.00
0.0
2.1
—
2507.14
—
0
7
5
53
0.94
-0.00
4.8
2.8
1.02
1.02
ratio
—
5
48
0
9
0.00
-0.00
0.0
1.8
—
4.04
—
0
9
0
6
0.00
-0.00
0.0
2.3
—
8.05
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
497.67
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
6.30
—
0
7

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_TRAUMAT_CEREBRAL_OEDEMA – Traumatic cerebral oedema

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).