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Acute nephritic syndrome

DOID EFO Endpoint Browser PheWeb

N14_ACUTENEPHRITIC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N00#
  • Hospital discharge: ICD-9 — 580
  • Hospital discharge: ICD-8 — 580
  • Hospital discharge: excluded ICD-9 — 5804
  • Cause of death: ICD-10 — N00#
  • Cause of death: ICD-9 — 580
  • Cause of death: ICD-8 — 580
  • Cause of death: excluded ICD-9 — 5804

2 out of 7 registries used, show all original rules.

868

4. Check minimum number of events

None

868

5. Include endpoints

None

868

6. Filter based on genotype QC (FinnGen only)

774

Control definitions (FinnGen only)

Control exclude
N14_GLOMERULAR

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N00-N08
Name in latin
Syndroma nephriticum acutum

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6888 2571 4253
Only index persons 5423 2070 3353
Unadjusted period prevalence (%)
Whole population 0.10 0.07 0.12
Only index persons 0.11 0.08 0.13
Median age at first event (years)
Whole population 33.02 34.02 32.14
Only index persons 28.39 28.38 28.39

-FinnGen-

Key figures

All Female Male
Number of individuals 774 319 455
Unadjusted period prevalence (%) 0.17 0.11 0.21
Median age at first event (years) 31.79 28.77 33.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
808
Matched controls
8080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
58099
ICD-8 Finland
Acute nephritis
+∞
307.7
366
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
65.6
212.8
118
21
N00.9
ICD-10 Finland
Acute nephritic syndrome, Unspecified
+∞
191.5
176
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
31.5
190.9
128
48
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
32.7
178.8
118
42
Z94.0
ICD-10 Finland
Kidney transplant status
64.9
156.9
87
15
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
65.1
148.0
82
14
A11CC03
ATC
alfacalcidol; systemic
22.0
145.0
111
58
L04AA06
ATC
mycophenolic acid; systemic
24.7
137.5
100
46
A12AA04
ATC
calcium carbonate; oral
30.9
129.0
86
31
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
47.1
116.7
69
16
127
Kela drug reimbursment
Transplant complication
23.6
115.5
85
40
R80
ICD-10 Finland
Isolated proteinuria
63.1
115.0
64
11
N18.8
ICD-10 Finland
Other chronic renal failure
21.8
112.8
86
44
L04AD01
ATC
ciclosporin; systemic
19.5
107.4
86
49
TK800
NOMESCO Finland
Hemodialysis
17.6
106.8
90
57
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
47.9
105.4
62
14
N18.0
ICD-10 Finland
End-stage renal disease
40.8
104.6
64
17
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
8.3
102.1
149
214
L04AA01
ATC
[U] ciclosporin
29.6
101.0
68
25
B03XA02
ATC
darbepoetin alfa; parenteral
17.3
94.4
80
51
Z49.1
ICD-10 Finland
Extracorporeal dialysis
23.5
91.3
67
31
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
36.2
80.8
51
15
V03AE01
ATC
polystyrene sulfonate; oral
28.9
79.7
54
20
Z49.0
ICD-10 Finland
Preparatory care for dialysis
34.0
70.0
45
14
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
69.8
66
*
H02AB04
ATC
methylprednisolone; systemic
4.3
68.6
220
642
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
703.8
67.0
65
*
L04AD02
ATC
tacrolimus; systemic
19.8
66.2
52
28
N00.0
ICD-10 Finland
Acute nephritic syndrome, Minor glomerular abnormality
+∞
64.4
61
*
B03XA01
ATC
erythropoietin; parenteral
23.2
62.7
46
21
N04.0
ICD-10 Finland
Nephrotic syndrome, minor glomerular abnormality
+∞
58.0
55
*
C03CA01
ATC
furosemide; systemic
3.2
55.7
352
1572
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
104.0
53.6
58
6
KA1AE
NOMESCO Finland
Kidney ultrasound examination
9.0
53.0
68
82
137
Kela drug reimbursment
Uraemia requiring dialysis
89.2
52.7
58
7
L04AX01
ATC
azathioprine; systemic
6.8
51.5
85
137
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
47.9
192
641
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
166.1
45.3
47
*
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
+∞
43.1
41
*
N00.2
ICD-10 Finland
Acute nephritic syndrome, Diffuse membranous glomerulonephritis
+∞
42.0
40
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.7
39.1
98
231
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.6
38.8
78
152
N03.0
ICD-10 Finland
Chronic nephritic syndrome, minor glomerular abnormality
+∞
37.8
36
*
205
Kela drug reimbursment
Chronic hypertension
2.7
37.0
276
1294
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
36.7
35
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.2
36.1
79
166
N03.2
ICD-10 Finland
Chronic nephritic syndrome, diffuse membranous glomerulonephritis
+∞
35.7
34
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.4
35.4
97
245
5809A
ICD-9 Finland
Acute glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS ACUTA NUD,EI NEFR SDR]
+∞
34.6
33
*
N04.2
ICD-10 Finland
Nephrotic syndrome, diffuse membranous glomerulonephritis
+∞
33.6
32
*
B05DA
ATC
Isotonic solutions
66.3
33.3
38
6
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
11.0
32.4
35
33
N00.8
ICD-10 Finland
Acute nephritic syndrome, Other
+∞
31.5
30
*
Z49.2
ICD-10 Finland
Other dialysis
53.7
30.6
36
7
N00.3
ICD-10 Finland
Acute nephritic syndrome, Diffuse mesangial proliferative glomerulonephritis
+∞
30.4
29
*
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
+∞
30.4
29
*
B05DB
ATC
Hypertonic solutions
59.0
29.3
34
6
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
6.9
27.9
44
67
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.7
27.0
52
97
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
30.4
26.5
35
12
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
26.2
25
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
26.2
25
*
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
26.2
25
*
C02AC05
ATC
moxonidine; oral
4.4
25.2
66
160
196
Kela drug reimbursment
Paricalcitol and cinacalcet
40.2
25.0
31
8
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.6
24.9
89
270
58199
ICD-8 Finland
Nephrotic syndrome
+∞
24.1
23
*
58399
ICD-8 Finland
Nephritis, unqualified
+∞
24.1
23
*
N19
ICD-10 Finland
Unspecified kidney failure
4.6
23.3
57
131
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
22.9
291
1667
A12AA12
ATC
[U] calcium acetate
236.4
22.7
23
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
33.4
22.5
29
9
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.6
22.2
78
234
58209
ICD-8 Finland
Chronic nephritis, Unspecified
+∞
22.0
21
*
M04AA01
ATC
allopurinol; systemic
2.6
21.9
146
631
C09AA02
ATC
enalapril; systemic
2.3
21.5
191
941
V03AE02
ATC
sevelamer; oral
34.8
21.2
27
8
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
61.7
21.0
24
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.7
20.3
126
524
N03.5
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
19.9
19
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
75.4
19.8
22
*
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
15.3
19.0
31
21
ZX120
NOMESCO Finland
Intravenous
2.8
18.8
102
395
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
53.8
18.0
21
*
TK810
NOMESCO Finland
Hemofiltration
23.4
17.8
25
11
N00.5
ICD-10 Finland
Acute nephritic syndrome, Diffuse mesangiocapillary glomerulonephritis
+∞
17.8
17
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
17.8
17
*
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
+∞
17.8
17
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
29.5
17.5
23
8
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
32.2
17.1
22
7
321
Kela drug reimbursment
Paricalcitol and cinacalcet
17.9
17.0
26
15
H05BX01
ATC
cinacalcet; oral
19.8
17.0
25
13
C08CA02
ATC
felodipine; oral
2.7
16.8
97
388
7151
FHL
Kidney transplantation
173.4
16.6
17
*
L01AA01
ATC
cyclophosphamide; systemic
23.6
16.5
23
10
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
41.0
16.4
20
5
V03AE03
ATC
lanthanum carbonate; oral
30.7
16.2
21
7
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
21.5
16.0
23
11
N00.7
ICD-10 Finland
Acute nephritic syndrome, Diffuse crescentic glomerulonephritis
+∞
15.7
15
*
5809B
ICD-9 Finland
Acute glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS ACUTA NUD,NEFR SDR]
+∞
15.7
15
*
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
+∞
15.7
15
*
WW200
NOMESCO Finland
Immunization
4.5
15.6
39
91
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
163.0
15.5
16
*
C08CA01
ATC
amlodipine; oral
1.8
15.0
325
2169
N00.1
ICD-10 Finland
Acute nephritic syndrome, Focal and segmental glomerular lesions
+∞
14.6
14
*
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
14.6
14
*
N04.3
ICD-10 Finland
Nephrotic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
14.6
14
*
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
+∞
14.6
14
*
H02AB06
ATC
prednisolone; systemic
1.8
14.6
398
2841
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
14.2
106
479
RD210, ,
NOMESCO Finland
5.8
13.7
25
44
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
13.6
161
876
R31
ICD-10 Finland
Unspecified haematuria
2.3
13.6
112
528
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
13.6
401
2908
78930
ICD-8 Finland
Abnormal urinary constituents of unspecified cause, Haematuria
16.5
13.5
21
13
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
142.3
13.5
14
*
C08CA05
ATC
nifedipine; systemic
3.0
13.5
62
219
C02CA01
ATC
prazosin; oral
6.2
13.5
23
38
C10AA05
ATC
atorvastatin; oral
1.8
13.3
353
2477
C08CA13
ATC
lercanidipine; oral
2.2
13.2
130
658
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
4.9
13.2
29
61
M10.9
ICD-10 Finland
Gout, unspecified
2.6
12.9
76
306
TK820
NOMESCO Finland
Peritoneal dialysis
50.9
12.9
15
*
3AC01, ,
NOMESCO Finland
11.8
12.9
23
20
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
12.8
118
582
5808A
ICD-9 Finland
Acute glomerulonephritis, With other specified pathological lesion in kidney[GLOMERULONEPHRITIS ACUTA ALIA,EI NEFR SDR]
+∞
12.5
12
*
L01BB01, ,
ATC
132.0
12.5
13
*
A46
ICD-10 Finland
Erysipelas
2.1
12.3
135
713
I15.0
ICD-10 Finland
Renovascular hypertension
21.7
12.0
17
8
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.1
12.0
25
50
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
11.9
34
88
R50.9
ICD-10 Finland
Fever, unspecified
2.0
11.7
141
768
5828A
ICD-9 Finland
Chronic glomerulonephritis, With other specified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA ALIA DEF,EI NEFR SDR]
+∞
11.5
11
*
5813A
ICD-9 Finland
Nephrotic syndrome, With lesion of minimal change glomerulonephritis
+∞
11.5
11
*
R4190
NOMESCO Finland
Nutritional therapy
3.1
11.4
48
161
H02AB09
ATC
hydrocortisone; systemic
4.1
11.3
31
78
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
35.6
11.3
14
*
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
4.5
11.3
27
61
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
11.4
11.1
20
18
K65.0
ICD-10 Finland
Acute peritonitis
8.7
10.6
22
26
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.0
10.6
47
163
M10.3
ICD-10 Finland
Gout due to impairment of renal function
14.4
10.5
17
12
WX202
NOMESCO Finland
Supraclavicular plexus blockade
5.5
10.4
20
37
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
+∞
10.4
10
*
5819X
ICD-9 Finland
Nephrotic syndrome with unspecified pathological lesion in kidney
+∞
10.4
10
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
10.4
46
159
M05BA04
ATC
alendronic acid; oral
2.5
10.3
68
290
U14
ICPC
Kidney symptom/complaint
5.1
10.1
21
42
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
10.0
96
479
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
20.3
9.8
14
7
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
20.3
9.8
14
7
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
9.8
564
6426
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
101.2
9.4
10
*
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
17.8
9.4
14
8
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
9.4
9
*
PBM09
NOMESCO Finland
Closure of arteriovenous fistula of brachial artery
+∞
9.4
9
*
N04.4
ICD-10 Finland
Nephrotic syndrome, diffuse endocapillary proliferative glomerulonephritis
+∞
9.4
9
*
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
9.4
9
*
D638, N188,
ICD-10 Finland
+∞
9.4
9
*
A41.9
ICD-10 Finland
Sepsis, unspecified
3.1
9.4
39
130
ZXD05
NOMESCO Finland
Urgent procedure
1.7
9.4
238
1618
C07AB02
ATC
metoprolol; systemic
1.8
9.4
160
974
C09CA01
ATC
losartan; oral
1.7
9.3
209
1375
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
9.3
153
921
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
9.2
85
419
A02BC01
ATC
omeprazole; systemic
1.7
9.1
213
1415
PB1BC
NOMESCO Finland
Extensive angiography of upper extremity with X-ray
37.1
9.0
11
*
U88
ICPC
Glomerulonephritis/nephrosis
37.1
9.0
11
*
5997A
ICD-9 Finland
Other disorders of urethra and urinary tract, Haematuria
18.8
9.0
13
7
C09CA07
ATC
telmisartan; oral
2.3
8.9
66
296
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.1
8.8
24
60
K65.9
ICD-10 Finland
Peritonitis, unspecified
50.5
8.7
10
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
50.5
8.7
10
*
L04AA05
ATC
[U] tacrolimus
50.5
8.7
10
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
8.6
81
401
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
8.5
215
1454
H02AB07
ATC
prednisone; oral
1.9
8.5
109
605
UJF32
NOMESCO Finland
Coloscopy
1.7
8.5
205
1372
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
91.0
8.4
9
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
91.0
8.4
9
*
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
91.0
8.4
9
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
8.4
148
908
J01MA12
ATC
levofloxacin; systemic
1.8
8.4
154
956
KBV00
NOMESCO Finland
Insertion of stent into ureter
9.6
8.3
16
17
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
8.3
222
1523
M31.3
ICD-10 Finland
Wegener granulomatosis
14.7
8.2
13
9
C07AG02
ATC
carvedilol; oral
2.4
8.2
55
236
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.4
8.2
58
255
N25.0
ICD-10 Finland
Renal osteodystrophy
22.3
8.0
11
5
A12BA01
ATC
potassium chloride; oral
2.9
8.0
36
126
XPX08
NOMESCO Finland
Intraoperative flow measurement
6.7
7.9
19
29
J01MA14
ATC
moxifloxacin; systemic
2.1
7.8
78
396
RS220, ,
NOMESCO Finland
6.5
7.7
19
30
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
45.4
7.7
9
*
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
12.0
7.6
13
11
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
25.3
7.6
10
*
3025
Kela drug reimbursment
Calcium carbonate
10.2
7.5
14
14
R04.0
ICD-10 Finland
Epistaxis
2.1
7.5
68
333
JN4AD
NOMESCO Finland
Body CT examination
1.9
7.4
97
541
WW400
NOMESCO Finland
Plasmaferesis
80.8
7.4
8
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
7.3
38
144
A10AC01
ATC
insulin (human); parenteral
2.1
7.3
66
322
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.6
7.3
24
69
N08.2*D89.82
ICD-10 Finland
Nepropathy caused by deposition of the light chain of the immunoglobulins
+∞
7.3
7
*
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
7.3
7
*
H05BX02
ATC
paricalcitol; systemic
+∞
7.3
7
*
5829A
ICD-9 Finland
Chronic glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA NUD ,EI NEFR SDR]
+∞
7.3
7
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
7.3
94
522
A02BC02
ATC
pantoprazole; systemic
1.5
7.3
522
4409
J01DB01
ATC
cefalexin; oral
1.6
7.2
645
5717
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
7.2
42
169
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
4.0
7.2
20
51
1XC02, ,
NOMESCO Finland
8.0
7.1
15
19
R60.9
ICD-10 Finland
Oedema, unspecified
2.4
7.1
48
207
C09CA06
ATC
candesartan; oral
1.6
7.1
183
1239
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.1
299
2262
C10AA01
ATC
simvastatin; oral
1.5
7.1
305
2317
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
10.1
7.0
13
13
C10AA04
ATC
fluvastatin; oral
2.0
7.0
72
369
B01AA03
ATC
warfarin; systemic
1.7
7.0
146
936
J01FF01
ATC
clindamycin; systemic
1.6
7.0
203
1413
Z2446
NOMESCO Finland
Social worker
2.2
6.9
60
288
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
6.9
113
676
B01AC04
ATC
clopidogrel; oral
1.7
6.9
132
826
B01AB10
ATC
tinzaparin; parenteral
1.9
6.7
88
492
212
Kela drug reimbursment
Gout
3.8
6.7
20
54
Y0699
ICD-8 Finland
Examination of the urinary and genital organs, Urinary organs. Does not include urine tests to determine endocrine and metabolic disorders (Y 00.99)
7.9
6.6
14
18
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
7.9
6.6
14
18
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
6.6
276
2077
R60.1
ICD-10 Finland
Generalized oedema
10.1
6.5
12
12
N28.9
ICD-10 Finland
Disorder of kidney and ureter, unspecified
10.1
6.5
12
12
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
6.5
81
445
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.2
6.4
25
81
ZX108
NOMESCO Finland
Inhalation
6.6
6.4
15
23
I50.1
ICD-10 Finland
Left ventricular failure
2.3
6.3
45
200
N04.89
ICD-10 Finland
Nephrotic syndrome, other
+∞
6.3
6
*
N00
ICD-10 Finland
Acute nephritic syndrome
+∞
6.3
6
*
B05D
ATC
PERITONEAL DIALYTICS
+∞
6.3
6
*
N04.5
ICD-10 Finland
Nephrotic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
6.3
6
*
N03.7
ICD-10 Finland
Chronic nephritic syndrome, diffuse crescentic glomerulonephritis
+∞
6.3
6
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
6.3
6
*
6112
FHL
Installation of a peritoneal dialysis or lavage catheter in an operating room
+∞
6.3
6
*
58200
ICD-8 Finland
Chronic nephritis, Cum uraemia
+∞
6.3
6
*
TKA00
NOMESCO Finland
Needle biopsy of kidney or pelvis of kidney
+∞
6.3
6
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
6.0
167
1145
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
5.6
6.0
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
67
10
72.97
123.33
2.1
1.7
—
—
—
0
0
74
29
27.99
107.61
28.9
36.8
80.67
145.74
ug/l
4.77
66
23
259
640
5.48
103.04
23.3
7.0
12.43
9.31
mmol/l
8.21
252
615
209
492
5.38
86.68
13.2
3.9
128.81
81.20
ng/l
6.48
198
432
293
950
4.27
80.56
24.4
5.6
1.14
1.03
mmol/l
6.94
287
884
77
70
12.05
73.81
3.4
2.4
2.77
0.72
g/24h
2.02
47
41
58
51
12.17
56.58
4.9
2.9
2309.43
628.31
mg
3.80
58
51
124
287
4.92
51.01
3.1
1.5
12.90
12.60
iu/ml
—
10
10
39
22
18.58
48.37
6.2
3.8
—
—
—
0
0
323
1557
2.79
41.97
6.7
2.6
3.39
5.37
e6/l
2.41
308
1424
98
250
4.32
35.29
1.7
1.2
—
—
—
0
0
48
62
8.17
35.21
2.4
2.5
—
—
—
0
0
90
219
4.50
34.41
2.4
1.4
0.25
0.24
g/l
0.70
84
209
109
311
3.90
33.66
2.9
1.9
1.55
1.50
g/l
0.24
100
278
136
461
3.34
32.31
2.5
2.7
—
—
—
0
0
73
163
4.82
30.97
2.5
1.4
—
—
—
0
0
154
576
3.07
30.94
3.4
2.8
62.48
66.84
g/l
6.72
145
534
359
2040
2.37
30.74
16.9
4.1
7.39
7.40
ph
1.79
314
1443
69
150
4.94
30.21
2.9
1.4
148.06
162.24
au/ml
0.33
16
43
393
2342
2.32
29.88
11.1
4.0
36.91
5.72
mg/mmol
8.29
334
1495
388
2302
2.32
29.79
9.8
3.3
189.13
35.95
mg/l
8.36
331
1522
85
223
4.14
29.37
3.0
4.2
69.52
73.83
mg/l
0.06
70
187
85
223
4.14
29.37
3.0
4.1
49.87
40.67
mg/l
0.39
70
190
404
2458
2.29
28.97
10.8
3.3
6.90
8.11
mmol/l
8.15
373
2088
381
2273
2.28
28.51
9.5
3.3
28.41
87.78
e6/l
1.31
333
1741
60
123
5.19
28.08
9.4
3.1
12.09
9.10
pmol/l
1.04
60
123
178
758
2.73
27.94
14.0
3.8
5.86
5.77
kpa
0.58
173
741
70
166
4.52
27.54
1.9
1.3
279.13
262.05
u/ml
0.15
45
96
172
731
2.72
27.03
13.9
3.8
1.01
1.80
mmol/l
1.96
152
638
88
252
3.80
26.87
10.5
3.9
878.05
195.66
mg/l
2.39
64
114
175
762
2.66
26.14
13.7
3.9
7.37
7.39
ph
4.11
127
435
77
205
4.05
26.03
3.2
3.8
1.64
2.49
ratio
0.78
38
113
183
836
2.54
24.64
3.3
1.6
—
—
—
0
0
459
3068
2.15
24.59
21.1
6.9
1.21
1.21
mmol/l
0.46
447
2838
498
3445
2.16
24.27
25.3
7.3
1.21
1.21
mmol/l
0.09
456
2983
250
1324
2.29
24.08
7.1
2.9
471.67
548.92
mosm/kgh2o
9.83
234
1160
44
79
5.83
23.74
1.1
1.3
—
—
—
0
0
454
3048
2.12
23.72
16.4
5.2
34.31
35.85
g/l
6.87
444
2874
318
1874
2.15
23.35
6.0
2.9
382.78
351.21
umol/l
5.97
303
1669
328
1960
2.13
23.19
8.8
3.2
0.21
0.38
e6/l
2.30
282
1439
147
635
2.61
22.04
18.4
9.8
—
—
—
0
0
81
251
3.48
21.91
1.7
1.3
—
—
—
0
0
140
599
2.62
21.37
6.4
2.4
0.17
0.30
e6/l
0.89
140
574
395
2595
2.02
21.02
11.6
3.9
109.42
98.65
e6/l
0.06
338
1834
25
7
36.79
19.93
11.0
15.9
4.93
5.43
mmol/l
—
25
7
502
3642
2.00
19.56
8.0
3.7
0.01
0.00
estimate
0.40
109
763
223
1216
2.15
19.38
5.9
3.7
0.80
0.82
mmol/l
1.61
215
1158
225
1232
2.15
19.34
6.7
2.9
0.55
0.98
e6/l
3.43
156
672
430
2973
1.95
19.12
4.4
2.5
76.51
76.55
nmol/l
0.01
413
2688
209
1123
2.16
18.79
3.2
2.4
29.21
29.64
s
0.54
204
1096
54
141
4.03
18.69
1.6
1.7
—
—
—
0
0
505
3706
1.97
18.61
8.0
3.7
0.00
0.42
estimate
0.51
103
724
141
644
2.44
18.61
5.0
2.8
71.17
69.44
e9/l
0.22
94
483
198
1052
2.17
18.26
3.4
1.7
—
—
—
0
0
500
3680
1.94
18.00
8.1
3.7
0.01
3.92
estimate
0.80
108
775
191
1024
2.13
17.09
2.9
2.0
—
—
—
0
0
39
85
4.77
16.97
1.3
1.2
—
—
—
0
0
418
2960
1.85
16.32
7.1
3.3
6.37
6.20
ph
2.37
226
1702
351
2362
1.86
16.06
10.0
6.6
—
—
—
0
0
76
273
2.97
16.04
1.9
1.8
3.89
7.66
iu/ml
0.94
17
70
26
19
14.10
15.58
3.1
3.6
0.62
0.62
mmol/l
0.10
26
19
125
588
2.33
15.28
4.2
2.7
9.46
10.85
g/l
2.52
119
545
198
1142
1.97
14.22
7.7
3.1
1.43
1.73
e6/l
0.38
129
581
66
237
2.94
13.93
2.5
2.6
9.29
10.75
g/l
1.81
61
214
172
966
1.99
13.24
1.5
1.4
463.75
487.24
titre
0.05
32
199
208
1256
1.88
12.87
3.5
1.9
—
—
—
0
0
292
1973
1.75
12.37
8.4
4.5
—
—
—
0
0
507
3990
1.73
12.25
14.5
10.2
4.46
4.10
e9/l
2.17
463
3484
545
4389
1.74
11.98
7.5
4.5
1467.20
587.79
e6/l
—
10
63
476
3704
1.69
11.78
11.0
6.8
0.19
0.20
e9/l
0.11
433
3264
465
3604
1.68
11.61
11.0
6.6
0.04
0.04
e9/l
0.16
424
3109
288
1966
1.72
11.61
5.7
2.9
0.43
0.07
—
7
46
471
3665
1.68
11.56
11.1
6.6
1.82
1.94
e9/l
1.36
431
3254
463
3592
1.68
11.45
11.0
6.6
0.62
0.59
e9/l
1.53
422
3095
136
740
2.01
11.33
8.4
9.6
95.17
95.39
%
0.18
130
718
45
146
3.20
11.30
7.2
3.3
—
—
—
0
0
32
83
3.97
11.20
5.0
4.0
10.84
10.07
%
0.61
32
83
48
169
2.96
10.50
2.0
1.2
—
—
—
0
0
119
637
2.02
10.34
3.6
2.2
0.00
0.02
estimate
0.50
29
141
98
488
2.15
10.32
9.7
3.6
7.40
7.42
ph
1.89
90
408
21
25
8.59
10.09
1.1
1.1
—
—
—
0
0
21
25
8.59
10.09
1.1
1.0
—
—
—
0
0
18
16
11.48
10.09
1.0
1.0
—
—
—
0
0
276
1933
1.65
9.74
4.2
3.0
—
—
—
0
0
20
40
5.10
9.61
1.2
1.7
—
—
—
0
0
94
477
2.10
9.41
2.2
1.7
1.14
1.45
g/l
1.10
87
443
557
4647
1.64
9.38
10.9
4.3
—
3.46
—
0
11
104
549
2.03
9.36
2.3
1.6
—
—
—
0
0
48
181
2.76
9.29
4.5
3.5
2.96
1.97
index
0.50
25
109
140
821
1.85
9.23
8.6
9.2
7.42
7.41
ph
0.24
85
461
139
814
1.85
9.21
8.5
9.2
0.90
0.92
mmol/l
0.01
110
673
424
3326
1.58
9.17
11.4
6.8
8.93
8.96
%
0.10
416
3143
121
686
1.90
8.85
2.3
2.7
0.22
0.21
g/l
0.73
115
640
139
825
1.83
8.80
2.4
1.7
—
—
—
0
0
420
3314
1.56
8.66
11.5
6.7
2.76
2.91
%
0.84
413
3126
429
3404
1.55
8.61
11.3
6.8
26.15
27.64
%
2.14
423
3250
419
3312
1.55
8.52
11.6
6.8
0.67
0.69
%
0.27
411
3124
29
86
3.46
8.42
1.2
1.1
—
—
—
0
0
71
341
2.19
8.18
4.3
2.2
0.00
2.16
estimate
0.50
22
116
25
70
3.65
7.90
1.2
1.1
—
—
—
0
0
40
151
2.73
7.75
5.6
2.7
91.86
89.72
%
1.50
40
146
274
2006
1.55
7.66
8.5
3.8
0.00
0.00
estimate
0.80
94
711
251
1802
1.57
7.65
3.0
2.3
2.85
2.89
mg/l
0.07
229
1548
37
135
2.82
7.64
7.0
3.3
2.30
2.38
mmol/l
0.06
24
83
25
73
3.50
7.44
1.4
1.2
170.00
212.00
titre
—
5
10
248
1792
1.55
7.28
6.7
4.5
94.03
88.74
%
2.60
241
1763
294
2207
1.52
7.24
2.4
2.2
206.36
283.21
u/l
0.52
283
2102
116
694
1.78
7.10
2.5
2.2
335.42
382.64
nmol/l
1.67
110
654
400
3230
1.47
6.74
6.8
3.0
189.05
140.64
ug/l
3.31
384
3023
292
2217
1.50
6.70
3.5
2.7
58.63
62.58
u/l
0.53
270
2068
33
122
2.78
6.67
2.2
1.5
0.86
0.70
g/l
0.33
25
98
402
3261
1.46
6.55
20.2
14.1
1.25
1.25
inr
0.03
344
2711
59
290
2.12
6.44
2.5
1.8
3.74
2.24
ug/l
0.34
53
260
76
410
1.94
6.43
4.8
5.7
—
—
—
0
0
67
349
2.00
6.26
11.7
3.7
—
—
—
0
0
596
5249
1.52
6.21
15.5
8.5
79.28
79.36
u/l
0.01
582
4983
39
164
2.45
6.13
3.6
2.4
127.12
131.08
g/l
0.45
33
131
24
80
3.06
5.84
1.6
1.3
1078.65
2143.39
e6/l
1.03
17
51
17
35
4.94
5.76
1.9
1.7
—
—
—
0
0
439
3679
1.42
5.68
7.3
7.2
10.17
11.78
umol/l
2.89
420
3522
21
66
3.24
5.62
1.5
1.3
—
—
—
0
0
21
68
3.14
5.37
1.6
1.4
8057.92
30690.00
e6/l
1.47
12
34
16
44
3.69
5.22
6.3
4.8
0.75
0.98
index
0.58
16
44
294
2325
1.42
5.14
6.6
3.4
2.33
2.35
mmol/l
1.43
282
2114
40
185
2.22
5.11
1.3
1.2
2.96
10.34
u/ml
—
5
33
38
172
2.27
5.11
2.3
1.6
14817.22
8535.84
e6/l
0.49
27
123
103
654
1.66
5.07
6.1
5.0
1.03
0.98
%
0.08
43
208
268
2092
1.42
5.01
9.8
6.5
—
—
—
0
0
482
4164
1.39
4.90
9.3
5.4
6.76
6.67
mmol/l
0.41
468
3962
98
620
1.66
4.89
6.0
5.2
0.17
0.15
%
0.10
42
174
377
3149
1.37
4.61
22.6
11.7
0.00
0.00
e9/l
0.58
322
2597
384
3219
1.37
4.58
4.1
2.9
—
—
estimate
—
0
0
214
1628
1.43
4.56
7.8
3.8
1.02
1.02
kg/l
1.33
171
1095
97
625
1.63
4.51
5.7
4.8
0.62
0.63
%
0.03
39
197
156
1119
1.49
4.51
1.9
1.7
1405.03
1176.99
nmol/l
1.75
133
851
37
177
2.14
4.39
4.0
2.3
293.19
65.07
ug/min
1.48
26
103
256
2031
1.38
4.23
2.0
1.7
18.69
19.98
nmol/l
0.73
237
1736
19
68
2.84
4.14
2.2
1.4
—
—
—
0
0
84
534
1.64
4.13
13.7
3.4
1.22
1.23
mmol/l
0.45
76
463
28
123
2.32
4.07
1.5
2.1
—
—
—
0
0
33
156
2.16
4.05
2.6
3.8
31.00
35.76
umol/l
0.68
33
144
26
112
2.37
3.96
3.0
1.9
1.76
1.69
mmol/l
0.12
26
107
95
631
1.57
3.91
6.7
5.4
0.03
0.18
%
1.24
36
160
14
37
3.83
3.90
4.9
2.2
523.00
481.52
min
0.91
14
25
27
122
2.26
3.71
1.4
1.3
52.00
57.75
mmol/l
0.44
21
106
26
116
2.28
3.68
1.8
1.4
—
—
—
0
0
19
73
2.64
3.66
1.4
1.2
—
—
—
0
0
332
2789
1.32
3.65
8.0
3.6
0.03
0.03
estimate
0.09
92
650
216
1706
1.36
3.59
3.8
2.5
—
—
—
0
0
18
68
2.68
3.58
1.1
1.1
—
—
—
0
0
9
17
5.34
3.51
1.0
1.4
—
—
—
0
0
17
63
2.73
3.51
1.6
1.3
407433.64
203861.31
e6/l
0.25
11
48
14
48
2.95
3.31
1.6
1.4
31.50
24.96
%
0.32
14
34
17
66
2.61
3.23
1.6
1.3
—
—
—
0
0
86
586
1.52
3.18
1.5
1.4
—
—
—
0
0
40
223
1.84
3.16
1.2
1.3
38.33
90.45
titre
—
6
22
90
624
1.50
3.07
2.3
1.8
—
—
—
0
0
49
295
1.70
3.01
3.1
2.8
—
—
—
0
0
49
296
1.70
2.97
3.6
2.7
20.75
20.92
s
0.11
44
272
17
69
2.50
2.97
2.1
1.7
—
—
—
0
0
16
63
2.57
2.97
2.7
2.2
40.46
37.37
%
0.31
16
63
160
1250
1.35
2.81
1.3
1.3
26.09
33.30
iu/ml
0.66
53
371
16
65
2.49
2.80
1.6
1.3
5.74
6.78
g/l
—
10
49
16
65
2.49
2.80
1.6
1.3
0.29
0.44
g/l
—
10
47
16
65
2.49
2.80
1.6
1.3
2.54
2.88
g/l
—
10
49
177
1407
1.33
2.76
1.7
1.7
467.29
19475447.10
pmol/l
0.96
154
1181
234
2786
0.77
2.74
3.6
3.1
—
—
—
0
0
270
2278
1.28
2.70
3.8
2.5
—
—
—
0
0
11
35
3.17
2.65
1.5
1.0
1125.73
1484.03
miu/ml
0.61
11
35
118
887
1.39
2.63
1.7
1.4
—
—
—
0
0
56
363
1.58
2.61
1.3
1.2
—
—
—
0
0
6
180
0.33
2.56
1.0
1.6
—
—
—
0
0
6
11
5.49
2.54
1.7
1.1
—
—
—
0
0
11
37
3.00
2.49
1.1
1.4
134.55
137.05
nmol/l
0.08
11
37
282
2414
1.26
2.46
3.9
3.5
33.66
34.00
u/l
0.03
270
2296
348
3056
1.24
2.41
2.3
2.1
97.76
95.19
pmol/l
0.48
202
1697
113
858
1.37
2.38
2.6
3.3
10.50
8.00
umol/l
0.50
97
761
35
206
1.73
2.37
4.7
7.8
1.19
1.27
mmol/l
0.32
27
181
199
1640
1.28
2.36
7.1
4.9
—
—
—
0
0
18
84
2.17
2.36
2.2
2.3
—
—
—
0
0
24
126
1.93
2.33
4.8
3.5
3.81
4.29
e9/l
0.47
24
126
9
28
3.24
2.31
2.4
1.2
156.22
169.09
mmol/24h
—
9
28
11
40
2.77
2.28
1.2
1.2
8.59
6.56
ug/l
0.42
11
34
20
99
2.05
2.27
1.6
1.5
—
—
—
0
0
20
99
2.05
2.27
1.6
1.5
—
—
—
0
0
20
99
2.05
2.27
1.6
1.5
—
—
—
0
0
20
99
2.05
2.27
1.6
1.5
—
—
—
0
0
7
18
3.91
2.25
1.4
1.8
32.57
27.78
%
—
7
18
18
86
2.12
2.24
2.8
2.4
33.94
33.30
pg
0.35
18
86
7
19
3.71
2.15
3.9
1.6
—
—
—
0
0
17
81
2.12
2.14
2.1
4.8
—
—
—
0
0
312
2736
1.23
2.13
5.2
3.8
68.30
58.88
ng/l
0.10
238
1965
8
25
3.22
2.10
1.3
1.1
—
—
—
0
0
81
595
1.40
2.10
2.8
2.4
6.24
7.89
ug/l
0.29
72
540
23
124
1.88
2.09
2.6
1.4
—
—
—
0
0
5
10
5.02
2.07
1.2
1.3
—
—
—
0
0
11
45
2.46
1.93
1.0
1.0
—
—
—
0
0
249
2151
1.23
1.93
4.0
3.3
6087.46
1221.30
ng/l
3.40
225
1845
35
221
1.61
1.88
1.2
1.4
149.27
258.04
miu/ml
—
10
103
5
12
4.19
1.82
3.8
1.0
—
—
—
0
0
5
12
4.19
1.82
3.8
1.0
—
—
—
0
0
5
12
4.19
1.82
3.8
1.0
—
—
—
0
0
18
325
0.54
1.82
1.2
1.7
—
—
—
0
0
26
153
1.72
1.81
1.4
1.4
3.29
15.96
e6/l
1.19
17
114
13
60
2.19
1.78
7.5
3.4
63.98
34.41
mg/l
0.49
13
46
188
1591
1.24
1.76
2.2
1.8
1.66
1.31
mg/l
0.71
155
1236
17
88
1.95
1.76
1.2
1.4
231.83
350.51
pmol/l
0.48
12
80
26
156
1.69
1.71
1.5
1.4
274.42
1326.77
e6/l
0.62
19
120
33
211
1.59
1.70
1.4
1.5
268.61
280.27
ug/g
0.11
23
134
12
55
2.20
1.68
1.0
1.1
—
—
—
0
0
45
312
1.47
1.63
2.5
2.3
—
—
—
0
0
21
122
1.74
1.56
1.1
1.2
5.78
5.44
u/ml
—
9
55
112
913
1.26
1.46
1.2
1.2
—
—
—
0
0
696
6721
1.26
1.46
35.7
16.0
24.55
24.79
mg/l
0.07
611
5525
7
28
2.51
1.45
1.1
2.0
39.26
41.52
g/l
—
7
28
22
133
1.67
1.43
1.1
1.1
—
—
—
0
0
23
141
1.65
1.43
1.3
1.1
—
—
—
0
0
15
82
1.84
1.36
5.3
5.3
7.69
7.04
mmol/l
0.30
15
68
5
17
2.95
1.36
1.2
2.1
—
—
—
0
0
26
167
1.58
1.36
5.1
3.4
54.92
58.41
%
0.67
26
167
27
176
1.55
1.33
1.3
1.4
431.89
488.97
mg/l
0.43
27
168
137
1156
1.22
1.33
1.3
1.3
11.88
10.43
u/ml
0.08
43
450
26
390
0.66
1.32
1.1
1.1
—
—
—
0
0
29
193
1.52
1.31
1.4
1.1
—
—
—
0
0
6
24
2.51
1.30
4.3
2.0
—
4241.50
—
0
16
22
138
1.61
1.27
1.2
1.4
—
—
—
0
0
24
154
1.58
1.27
1.4
1.3
3.93
3.68
mmol/l
0.85
24
145
8
35
2.30
1.27
1.3
1.1
492.76
152.02
iu/ml
—
8
35
13
71
1.84
1.20
1.1
1.4
—
—
—
0
0
106
881
1.23
1.19
3.0
2.6
184.41
117.70
ug/g
0.88
92
710
87
707
1.26
1.19
3.5
4.7
21.23
23.28
ug/l
0.04
67
597
17
102
1.68
1.17
1.2
1.2
—
—
—
0
0
5
20
2.51
1.15
1.0
2.0
—
—
—
0
0
316
2896
1.15
1.15
2.4
1.9
1.46
1.37
mmol/l
1.19
278
2469
69
548
1.28
1.14
9.8
3.7
—
—
—
0
0
46
345
1.35
1.13
1.6
1.7
0.41
0.34
mg/l
0.31
20
165
5
21
2.39
1.09
1.0
2.3
—
—
—
0
0
44
575
0.75
1.06
2.0
1.8
3.53
3.49
mmol/l
0.07
32
428
7
33
2.13
1.05
1.9
1.8
—
—
—
0
0
9
46
1.97
1.04
1.6
1.3
—
—
—
0
0
156
1371
1.17
0.99
5.8
4.1
561.02
451.33
ng/l
0.10
134
1075
5
23
2.18
0.98
2.0
2.5
10.81
10.23
mg/l
—
5
18
6
27
2.23
0.93
1.0
1.1
—
1033.33
—
0
6
10
55
1.83
0.92
1.0
1.1
91.60
101.11
pmol/l
—
10
55
164
1456
1.16
0.92
1.8
1.4
2.57
2.50
g/l
0.17
119
913
655
6356
1.16
0.92
8.4
6.4
39.62
39.31
mmol/mol
0.39
631
5989
700
6834
1.18
0.87
44.0
19.1
4.05
3.98
mmol/l
6.52
690
6696
11
64
1.73
0.86
1.2
1.2
—
—
—
0
0
35
456
0.76
0.85
1.1
1.2
—
—
—
0
0
699
6827
1.18
0.85
42.5
18.9
139.45
139.68
mmol/l
1.59
691
6702
220
2012
1.13
0.80
7.0
3.2
0.04
0.06
estimate
0.15
83
615
102
883
1.18
0.80
3.5
3.2
4.29
5.45
e9/l
0.90
95
784
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
163
1804
0.88
0.76
2.6
3.2
0.81
0.76
ug/l
0.30
109
1135
9
53
1.71
0.75
1.1
1.2
—
—
—
0
0
26
193
1.36
0.74
1.2
1.1
—
—
—
0
0
12
76
1.59
0.72
1.2
1.5
—
—
—
0
0
18
252
0.71
0.71
1.6
1.9
205.56
213.10
pmol/l
0.10
18
239
10
61
1.65
0.68
1.5
2.0
14.60
21.86
nmol/l
—
10
55
5
27
1.86
0.68
1.2
1.2
—
—
—
0
0
7
42
1.67
0.68
4.7
4.0
24.71
16.98
mu/l
—
7
42
90
784
1.17
0.67
1.5
1.4
—
—
—
0
0
16
111
1.45
0.66
3.1
2.7
—
—
—
0
0
5
29
1.73
0.64
2.2
1.2
5.36
6.61
mmol/l
—
5
29
5
29
1.73
0.64
3.0
2.4
3.84
1.70
umol/l
—
5
23
633
6478
0.89
0.63
6.2
5.1
5.97
5.97
mmol/l
0.04
599
5991
13
87
1.50
0.63
2.4
1.8
—
—
—
0
0
150
1361
1.13
0.63
3.7
3.1
2.46
2.45
mmol/l
0.69
140
1227
73
630
1.17
0.62
15.6
3.9
7.33
7.35
ph
0.38
63
463
36
441
0.81
0.58
1.3
1.2
48.98
136.28
u/ml
1.87
13
171
19
141
1.36
0.56
1.9
1.1
—
—
—
0
0
19
141
1.36
0.56
1.9
1.1
—
—
—
0
0
11
73
1.51
0.56
1.5
1.2
—
—
—
0
0
10
65
1.55
0.55
1.4
1.1
—
—
—
0
0
9
60
1.51
0.54
1.2
1.2
—
—
—
0
0
6
38
1.58
0.54
1.5
1.1
—
—
—
0
0
11
74
1.49
0.53
2.9
2.5
—
—
—
0
0
13
181
0.71
0.53
1.8
1.9
518.34
4.94
iu/l
—
6
68
58
668
0.86
0.51
1.4
1.4
—
—
—
0
0
13
92
1.42
0.50
1.6
1.4
—
—
—
0
0
724
7333
0.88
0.50
50.1
24.4
131.02
137.03
g/l
18.12
719
7259
527
5123
1.08
0.49
4.4
4.1
15.06
14.73
pmol/l
2.20
503
4700
724
7331
0.88
0.49
49.8
24.3
7.06
6.75
e9/l
3.69
714
7182
13
93
1.40
0.48
1.3
1.4
0.63
0.65
nmol/l
0.06
13
87
724
7330
0.88
0.48
50.6
24.9
39.47
40.78
%
9.72
718
7252
724
7330
0.88
0.48
49.6
24.3
4.36
4.54
e12/l
13.47
715
7183
724
7330
0.88
0.48
49.5
24.2
30.34
30.40
pg
0.44
719
7256
11
76
1.45
0.48
1.1
1.3
—
—
—
0
0
46
535
0.85
0.46
1.2
1.2
—
—
—
0
0
724
7327
0.89
0.46
49.6
24.2
91.47
91.08
fl
1.40
719
7255
724
7326
0.89
0.45
49.9
24.3
249.90
246.06
e9/l
0.87
717
7195
36
303
1.20
0.44
2.2
1.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
59.75
—
0
17
5
34
1.47
0.40
1.6
2.3
81.20
75.01
ug/l
—
5
34
150
1606
0.92
0.40
1.3
1.3
1.18
1.50
u/ml
0.31
43
465
0
18
0.00
0.40
0.0
2.2
—
16.67
—
0
18
24
196
1.23
0.39
3.9
3.1
1.35
1.57
mmol/l
0.66
24
191
11
81
1.36
0.36
2.1
1.3
21.05
25.86
ng/l
0.47
11
81
11
81
1.36
0.36
1.5
1.4
0.21
0.19
nmol/l
0.20
11
60
6
47
1.28
0.32
1.2
1.1
—
5.20
—
0
13
11
143
0.77
0.32
1.8
1.7
58.94
57.67
ug/l
0.04
11
124
27
315
0.85
0.31
1.7
1.9
38.93
40.54
nmol/l
0.14
27
304
7
97
0.72
0.31
1.0
1.1
—
—
—
0
0
31
269
1.16
0.29
1.0
1.1
—
—
—
0
0
8
108
0.74
0.29
2.0
1.5
—
—
—
0
0
8
110
0.72
0.29
2.1
1.6
—
—
—
0
0
645
6366
1.07
0.28
5.7
4.3
1.39
1.30
mmol/l
2.25
615
5893
676
6683
1.07
0.28
6.8
5.1
4.42
4.58
mmol/l
3.82
647
6262
10
128
0.78
0.27
1.1
1.1
2.00
4.09
u/ml
—
5
68
72
779
0.92
0.27
1.4
1.6
—
—
—
0
0
288
2971
0.95
0.26
5.0
5.4
4.09
2.29
ug/l
0.69
259
2696
5
73
0.68
0.26
4.0
2.3
—
—
—
0
0
59
542
1.10
0.24
3.6
2.4
6.00
6.06
ph
0.30
49
361
70
752
0.92
0.23
1.6
1.5
—
—
—
0
0
14
168
0.83
0.23
7.1
4.2
—
—
—
0
0
718
7125
1.07
0.22
42.9
20.7
114.91
78.78
umol/l
16.03
710
7051
683
6768
1.06
0.22
7.2
5.8
2.53
2.70
mmol/l
5.76
654
6317
19
220
0.86
0.21
5.6
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
52.36
—
0
11
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
85
801
1.07
0.20
2.0
2.4
13.04
13.57
nmol/l
0.24
77
734
0
14
0.00
0.20
0.0
5.1
—
7.64
—
0
14
12
144
0.83
0.20
1.1
1.1
0.09
2.33
u/ml
—
7
77
6
51
1.18
0.19
1.8
3.0
8.70
8.06
mmol/l
—
6
51
6
52
1.15
0.19
2.3
3.3
14.05
16.60
%
—
6
52
209
2027
1.04
0.18
1.6
1.5
—
—
—
0
0
25
279
0.89
0.18
4.0
1.9
—
—
—
0
0
25
279
0.89
0.18
6.2
1.9
—
—
—
0
0
75
709
1.06
0.17
1.5
1.5
—
—
—
0
0
13
110
1.18
0.17
1.0
1.2
—
—
—
0
0
25
277
0.90
0.16
4.6
2.0
—
—
—
0
0
25
277
0.90
0.16
4.7
2.0
—
—
—
0
0
8
70
1.14
0.16
1.0
1.1
—
—
—
0
0
8
71
1.13
0.16
2.1
2.1
—
—
—
0
0
21
188
1.12
0.15
4.7
2.9
—
—
—
0
0
712
7080
1.05
0.14
20.3
12.2
25.39
27.38
u/l
2.24
702
6906
8
96
0.83
0.13
6.0
3.0
—
—
—
0
0
270
2647
1.03
0.13
2.3
2.1
—
—
—
0
0
19
208
0.91
0.10
21.8
11.4
—
—
—
0
0
5
46
1.09
0.09
1.2
1.2
9.20
9.26
mm/h
—
5
46
5
46
1.09
0.09
1.4
1.2
—
—
—
0
0
27
289
0.93
0.09
1.3
1.3
—
—
—
0
0
12
133
0.90
0.07
4.2
3.0
0.84
0.89
nmol/l
0.18
12
115
620
6174
1.02
0.06
5.1
5.0
1.97
1.90
mu/l
0.47
595
5720
20
213
0.94
0.06
1.1
1.1
—
—
—
0
0
10
110
0.91
0.05
1.3
1.3
—
—
—
0
0
17
181
0.94
0.05
1.3
1.2
—
—
—
0
0
25
261
0.96
0.04
4.7
2.0
—
—
—
0
0
11
119
0.92
0.04
9.1
2.9
—
—
—
0
0
13
138
0.94
0.02
1.3
1.8
—
—
—
0
0
476
4749
1.01
0.01
4.2
3.5
62.79
49.76
u/l
1.57
460
4497
15
144
1.04
0.00
1.3
1.3
—
—
—
0
0
666
6654
1.01
0.00
6.7
5.0
1.38
1.42
mmol/l
1.64
638
6198
26
255
1.02
0.00
1.1
1.1
1.37
1.51
g/l
2.41
26
255
27
265
1.02
0.00
1.1
1.2
0.92
0.91
g/l
0.11
27
265
92
925
0.99
0.00
1.3
1.3
—
—
—
0
0
34
338
1.01
0.00
1.1
1.1
—
84.43
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
15
150
1.00
-0.00
3.4
3.8
28.43
29.77
mg/l
—
7
109
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
6.01
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
190.83
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
40.29
—
0
7
5
56
0.89
-0.00
1.2
1.5
197.96
170.77
pmol/l
—
5
56
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
77.40
—
0
5
8
81
0.99
-0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
0.22
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.8
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint N14_ACUTENEPHRITIC and mortality.

Females

Parameter HR [95% CI] p-value
N14_ACUTENEPHRITIC 2.352 [1.85, 2.99] < 0.001
Birth year 0.997 [0.99, 1.01] 0.542

During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 1006 females with N14_ACUTENEPHRITIC died.

Males

Parameter HR [95% CI] p-value
N14_ACUTENEPHRITIC 2.225 [1.81, 2.73] < 0.001
Birth year 0.991 [0.98, 1.0] 0.05

During the follow-up period (1.1.1998 — 31.12.2019), 333 out of 1234 males with N14_ACUTENEPHRITIC died.

Mortality risk

Mortality risk for people of age

years, who have N14_ACUTENEPHRITIC.

N-year risk Females Males
1 0.177% 0.529%
5 1.543% 3.105%
10 3.692% 7.535%
15 6.689% 13.671%
20 11.881% 22.28%

Relationships between endpoints

↥

Index endpoint: N14_ACUTENEPHRITIC – Acute nephritic syndrome

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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