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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Left side

Z21_LEFT_SIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 ZB0.0
  • Cause of death: ICD-10 ZB0.0

2 out of 7 registries used, show all original rules.

171

4. Check minimum number of events

None

171

5. Include endpoints

None

171

6. Filter based on genotype QC (FinnGen only)

137

Control definitions (FinnGen only)

Control exclude
Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z[AB]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 137 68 69
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 69.33 70.81 67.88

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
144
Matched controls
1440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZB0.0
ICD-10 Finland
Left side
+∞
202.1
142
*
WX111
NOMESCO Finland
Local infiltration anesthesia
26.4
75.5
61
39
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
18.5
53.1
49
39
M17.1
ICD-10 Finland
Other primary gonarthrosis
10.4
43.6
100
259
SPAT1212
SPAT
Extensive examination of musculoskeletal system
11.8
40.3
50
62
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
11.1
39.3
52
70
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
9.4
34.3
52
82
Z50.1
ICD-10 Finland
Other physical therapy
11.9
34.2
40
45
M16.1
ICD-10 Finland
Other primary coxarthrosis
7.6
31.8
64
137
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
7.6
30.7
59
120
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
5.8
21.8
53
131
ZB0.1
ICD-10 Finland
Right side
+∞
19.2
18
*
B01AB10
ATC
tinzaparin; parenteral
5.5
18.8
46
113
WX320
NOMESCO Finland
Spinalanesthesy
4.0
14.9
71
284
R4135
NOMESCO Finland
Rehabilitation for hearing problems
16.8
14.7
23
16
Z3231
NOMESCO Finland
Registered nurse
3.9
14.5
73
303
TPH04
NOMESCO Finland
Cathetrisation of vein
3.9
14.0
62
235
U07.2
ICD-10 Finland
COVID-19, virus not identified
4.7
13.6
38
102
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
4.9
13.4
35
89
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
4.0
13.2
50
169
B01AB05
ATC
enoxaparin; parenteral
3.6
12.8
80
374
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
6.1
12.5
24
46
B01AF01
ATC
rivaroxaban; oral
4.0
12.4
45
147
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.8
11.8
47
163
ZXD10
NOMESCO Finland
Scheduled procedure
0.1
10.5
8
410
E66.01
ICD-10 Finland
Obesity due to excess calories
4.7
9.9
25
61
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
3.5
9.1
37
128
M76.4
ICD-10 Finland
Tibial collateral bursitis [Pellegrini-Stieda]
95.4
8.5
9
*
M01AH05
ATC
etoricoxib; oral
3.2
8.5
110
723
N02BE01
ATC
paracetamol; systemic, rectal
26.3
8.3
143
1216
XQ845
NOMESCO Finland
Dermatoscopy
11.8
7.5
13
12
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
3.6
7.4
27
86
WZC30
NOMESCO Finland
Teaching
2.9
7.4
45
196
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.7
7.1
56
278
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
8.2
7.1
15
20
R74
ICPC
Upper respiratory infection acute
0.2
7.1
5
277
WVA20
NOMESCO Finland
Medicine administration
7.5
6.7
15
22
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
9.4
6.7
13
15
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
6.7
48
227
WZC00
NOMESCO Finland
Treatment plan or consultation
2.4
6.3
72
421
RTGKO, ,
NOMESCO Finland
+∞
6.3
6
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.5
6.2
58
310
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.7
6.1
21
64
M01AX05
ATC
glucosamine; oral
2.5
6.1
49
243

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
98
44
67.59
146.95
4.7
6.3
—
—
—
0
0
50
24
31.38
69.49
1.9
3.5
1.20
1.19
mmol/l
0.27
50
24
50
24
31.38
69.49
1.9
3.5
105.92
106.38
mmol/l
0.20
50
24
50
24
31.38
69.49
1.9
3.5
4.11
3.97
mmol/l
1.08
50
24
82
125
13.91
58.68
1.9
3.1
0.64
0.18
e6/l
0.61
82
120
83
150
11.70
50.99
4.5
4.2
2.19
1.77
mmol/l
0.61
73
126
58
65
14.27
50.97
4.4
4.7
0.81
0.80
%
0.09
58
59
61
75
13.38
50.25
4.7
4.5
1.36
1.47
%
0.39
61
69
137
519
34.67
46.47
7.4
4.0
—
—
—
0
0
73
125
10.82
46.30
4.5
5.6
0.14
0.21
%
—
7
39
73
136
9.86
42.69
4.5
5.4
2.06
1.04
%
—
8
50
118
389
12.26
40.09
6.6
3.3
0.03
0.25
—
32
8
122
424
13.29
39.15
6.9
3.8
0.02
0.00
estimate
0.49
45
140
50
90
7.98
28.99
1.9
2.8
0.76
0.62
%
2.35
50
90
127
570
11.40
27.98
7.4
4.5
0.12
0.00
estimate
1.24
49
140
114
467
7.92
27.44
6.1
3.8
—
—
—
0
0
134
647
16.42
27.06
4.1
3.2
—
—
estimate
—
0
0
88
304
5.87
25.08
6.0
6.4
—
—
—
0
0
130
756
8.40
17.17
7.6
4.3
0.00
0.00
estimate
-0.00
68
173
97
455
4.47
16.71
4.5
3.6
—
—
—
0
0
130
768
8.13
16.51
7.7
4.3
0.00
9.02
estimate
0.50
68
180
129
769
7.50
15.86
7.7
4.4
0.13
0.00
estimate
0.80
61
162
64
231
4.19
15.75
4.4
7.6
105.22
103.65
mmol/l
2.09
64
231
79
362
3.62
13.16
1.6
1.4
—
—
—
0
0
8
426
0.14
11.20
1.4
6.8
—
—
—
0
0
88
470
3.24
10.77
2.3
2.8
—
—
—
0
0
108
654
3.61
10.64
7.6
6.9
57.37
58.42
%
0.41
108
624
100
606
3.13
9.28
5.2
4.3
32.84
40.47
ng/l
0.41
88
461
24
60
4.60
9.21
1.8
2.0
—
—
—
0
0
62
334
2.50
6.58
2.3
1.8
1.35
1.51
mg/l
0.19
55
265
144
1287
+∞
6.44
29.1
17.0
—
—
—
0
0
58
308
2.48
6.29
1.6
1.9
364.54
457.33
pmol/l
2.80
50
251
37
161
2.75
5.99
2.2
3.2
4.18
5.74
e9/l
0.51
37
139
93
634
2.32
5.44
4.6
5.1
36.19
35.06
g/l
1.11
93
595
24
87
3.11
5.36
2.7
2.7
—
—
—
0
0
144
1318
+∞
5.02
26.4
22.6
140.28
139.62
mmol/l
3.31
144
1294
144
1320
+∞
5.02
26.1
22.7
4.07
4.00
mmol/l
3.30
144
1294
0
103
0.00
4.23
0.0
1.2
—
—
—
0
0
144
1338
+∞
4.00
32.5
25.5
81.42
80.76
umol/l
0.08
144
1324
19
76
2.73
3.55
1.2
1.4
—
—
—
0
0
6
6
10.36
3.53
2.3
1.7
—
—
—
0
0
144
1352
+∞
3.44
39.3
28.6
30.18
30.45
pg
1.01
144
1341
144
1352
+∞
3.44
39.3
28.7
90.88
91.56
fl
1.05
144
1341
144
1352
+∞
3.44
39.4
28.7
263.79
244.66
e9/l
1.98
144
1330
144
1352
+∞
3.44
39.4
28.7
4.44
4.46
e12/l
0.16
144
1324
144
1352
+∞
3.44
39.9
28.9
133.74
134.66
g/l
0.32
144
1339
144
1352
+∞
3.44
39.7
28.8
7.27
6.75
e9/l
1.07
144
1327
144
1352
+∞
3.44
39.4
29.3
33.51
40.27
%
6.64
144
1341
40
227
2.06
3.42
3.5
2.0
—
—
—
0
0
26
125
2.32
3.34
1.7
2.3
0.00
0.11
estimate
0.49
12
28
31
162
2.16
3.27
2.6
1.8
—
—
—
0
0
16
62
2.78
3.17
1.7
2.2
1.01
5.25
ug/l
0.47
16
56
5
172
0.27
2.92
2.0
1.6
—
—
—
0
0
7
13
5.60
2.90
1.1
1.3
—
—
—
0
0
35
542
0.53
2.68
2.8
2.2
—
—
—
0
0
32
496
0.54
2.39
2.0
3.4
2.36
2.35
mmol/l
0.22
32
441
6
13
4.76
2.29
1.7
2.4
—
—
—
0
0
32
485
0.56
2.16
4.0
4.6
7.38
7.40
ph
1.68
25
342
40
263
1.72
2.10
1.7
1.3
91.80
37.07
iu/ml
—
10
82
33
486
0.58
1.96
3.8
6.4
—
—
—
0
0
21
351
0.53
1.95
3.5
3.0
3.74
4.00
e6/l
0.10
21
325
6
16
3.86
1.95
1.2
1.4
—
—
—
0
0
0
52
0.00
1.92
0.0
3.5
—
—
—
0
0
64
492
1.54
1.75
2.9
3.6
72.25
58.62
mg/l
0.20
52
325
0
49
0.00
1.72
0.0
1.3
—
—
—
0
0
10
204
0.45
1.66
1.0
1.3
—
—
—
0
0
5
14
3.66
1.63
1.0
1.0
—
—
—
0
0
76
897
0.68
1.50
4.9
5.1
—
233.72
—
0
18
56
432
1.48
1.46
5.3
4.7
—
—
—
0
0
77
635
1.46
1.41
2.2
2.2
87.61
97.50
pmol/l
1.57
55
306
17
275
0.57
1.38
1.4
1.6
3.38
2.84
g/l
0.44
17
167
0
34
0.00
1.17
0.0
1.2
—
—
—
0
0
0
36
0.00
1.15
0.0
2.4
—
57.62
—
0
36
33
240
1.49
1.12
1.5
1.3
1.80
9.38
u/ml
1.66
25
89
7
132
0.51
1.05
7.3
4.4
—
—
—
0
0
0
32
0.00
0.96
0.0
1.3
—
—
—
0
0
14
86
1.70
0.95
1.1
1.3
—
—
—
0
0
7
128
0.52
0.93
1.4
2.8
10.54
10.28
g/l
—
7
114
60
501
1.34
0.92
2.8
3.5
6.92
7.82
mmol/l
1.16
60
407
8
138
0.56
0.89
1.4
1.5
—
—
—
0
0
8
139
0.55
0.88
1.8
2.5
0.20
0.22
g/l
—
8
128
9
151
0.57
0.84
1.4
1.4
—
—
—
0
0
0
24
0.00
0.80
0.0
3.2
—
32.21
—
0
24
0
25
0.00
0.80
0.0
2.3
—
—
—
0
0
0
26
0.00
0.79
0.0
1.1
—
—
—
0
0
6
107
0.54
0.76
7.0
3.2
175.67
242.49
ng/l
—
6
98
6
106
0.55
0.76
1.2
1.9
0.80
1.58
g/l
—
6
96
7
40
1.79
0.72
1.1
1.1
—
—
—
0
0
5
27
1.88
0.69
1.2
1.1
—
—
—
0
0
23
296
0.73
0.64
1.1
1.3
0.87
1.27
u/ml
0.36
13
79
0
20
0.00
0.61
0.0
1.5
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
0
20
0.00
0.61
0.0
3.5
—
—
—
0
0
0
20
0.00
0.61
0.0
1.3
—
—
—
0
0
12
172
0.67
0.60
1.3
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
2.0
—
89.45
—
0
21
0
21
0.00
0.60
0.0
3.8
—
—
—
0
0
0
22
0.00
0.60
0.0
1.4
—
879.29
—
0
17
51
452
1.20
0.43
4.1
4.4
0.00
0.00
estimate
-0.00
40
164
0
16
0.00
0.41
0.0
1.0
—
281.91
—
0
11
0
16
0.00
0.41
0.0
2.9
—
—
—
0
0
0
17
0.00
0.41
0.0
1.9
—
10.20
—
0
17
0
18
0.00
0.40
0.0
4.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
36820.50
—
0
10
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
15
190
0.76
0.38
1.5
1.3
—
—
—
0
0
5
76
0.65
0.37
1.0
1.3
—
—
—
0
0
24
200
1.24
0.37
1.8
1.4
993.33
623.53
titre
—
6
51
6
88
0.67
0.34
2.2
2.6
1.00
1.45
g/l
—
6
81
49
442
1.16
0.33
1.6
1.7
19.05
22.09
nmol/l
0.65
44
357
9
72
1.27
0.26
1.2
1.2
—
—
—
0
0
11
137
0.79
0.25
4.2
10.0
—
—
—
0
0
16
190
0.82
0.25
1.4
1.4
—
—
—
0
0
5
37
1.36
0.24
5.6
3.6
—
—
—
0
0
18
209
0.84
0.23
7.1
6.6
1.07
1.03
mmol/l
0.26
18
195
16
135
1.21
0.22
2.2
2.3
328.00
383.81
nmol/l
0.58
16
123
18
208
0.85
0.22
1.4
3.7
1.66
1.80
%
0.31
18
190
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
113.46
—
0
10
0
12
0.00
0.21
0.0
3.0
—
48.83
—
0
6
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
41.96
—
0
8
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
10
120
0.82
0.17
1.8
1.4
—
—
—
0
0
16
144
1.13
0.11
1.8
2.9
66.63
66.18
g/l
0.07
16
138
12
135
0.88
0.10
1.4
1.3
—
—
—
0
0
5
47
1.07
0.09
1.0
1.1
—
—
—
0
0
6
58
1.04
0.08
1.2
4.2
1.43
2.89
ratio
—
6
27
5
62
0.80
0.08
1.0
1.1
—
—
—
0
0
15
164
0.90
0.08
3.1
3.3
15.33
7.23
umol/l
0.67
15
151
11
119
0.92
0.04
1.0
2.7
—
—
—
0
0
12
123
0.97
0.00
3.1
4.1
99.00
82.38
ng/l
—
6
106
47
473
0.99
0.00
2.4
2.2
238.66
204.50
u/l
0.24
47
445
24
242
0.99
0.00
3.9
1.9
27.61
28.94
s
1.13
24
235
0
6
0.00
0.00
0.0
2.2
—
1.19
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
57
0.87
-0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.1
—
4.29
—
0
8
0
5
0.00
-0.00
0.0
1.6
—
10.08
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
0.61
—
0
5
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.3
—
31.70
—
0
5
6
61
0.98
-0.00
1.2
4.6
41.73
29.89
mg/l
—
6
53
0
5
0.00
-0.00
0.0
1.2
—
10.28
—
0
5
6
61
0.98
-0.00
1.2
4.6
62.38
44.10
mg/l
—
6
53
0
7
0.00
-0.00
0.0
1.0
—
148.43
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
204.67
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_LEFT_SIDE – Left side

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).