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R14

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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Use of dimethyl fumarate

Endpoint Browser

MSMED_DIMETHYL_FUMARATE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC — N07XX09

1 out of 7 registries used, show all original rules.

340

4. Check minimum number of events

Min. number of events 3
340

5. Include endpoints

None

340

6. Filter based on genotype QC (FinnGen only)

306

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 306 247 59
Unadjusted period prevalence (%) 0.08 0.09 0.03
Median age at first event (years) 41.11 40.71 42.77

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
326
Matched controls
3260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N07XX09
ATC
[U] dimethyl fumarate
+∞
307.7
326
*
G35
ICD-10 Finland
Multiple sclerosis
+∞
307.7
326
25
L04AX07
ATC
dimethyl fumarate; oral
2794.0
307.7
266
5
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
11992.3
307.7
323
17
L03AB07
ATC
interferon beta-1a; parenteral
314.1
307.7
168
11
109
Kela drug reimbursment
Multiple sclerosis
11992.3
307.7
323
17
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
+∞
307.7
326
16
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
48.4
291.5
237
170
H46
ICD-10 Finland
Optic neuritis
99.1
202.6
107
16
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
78.5
166.7
91
16
TAB00
NOMESCO Finland
Lumbar puncture
22.8
151.3
129
91
L03AX13
ATC
glatiramer acetate; parenteral
265.2
134.0
129
8
N86
ICPC
Multiple sclerosis
335.8
131.6
125
6
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
32.9
95.7
64
24
XA800
NOMESCO Finland
Neuropsychological investigation
15.2
95.5
96
87
XCK00
NOMESCO Finland
Perimetry
20.7
93.8
77
48
L04AA31
ATC
[U] teriflunomide
547.4
87.5
83
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
10.4
86.7
122
177
XKD06
NOMESCO Finland
Physiologic investigation of micturition
37.6
80.2
51
16
M03BX01
ATC
baclofen; systemic
25.0
78.6
58
28
L03AB08
ATC
interferon beta-1b; parenteral
478.3
78.4
75
*
ZX120
NOMESCO Finland
Intravenous
10.8
73.9
94
118
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
30.2
71.9
49
19
G04BD12
ATC
mirabegron; oral
11.6
69.4
81
90
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
25.4
66.1
48
22
XKD00
NOMESCO Finland
Uroflowmetry
12.8
64.6
69
67
N04BB01
ATC
amantadine; oral
117.8
62.6
66
7
164
Kela drug reimbursment
Fingolimod
115.6
61.5
65
7
R1250
NOMESCO Finland
Evaluation of functional capability
16.7
56.6
50
35
2AB04, ,
NOMESCO Finland
224.4
55.9
56
*
353
Kela drug reimbursment
Cladribine and fingolimod
98.4
52.9
57
7
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.9
48.1
47
39
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
11.4
47.9
54
56
L04AA27
ATC
[U] fingolimod
123.4
40.8
43
*
H02AB04
ATC
methylprednisolone; systemic
5.3
37.6
94
231
G36.9
ICD-10 Finland
Acute disseminated demyelination, unspecified
189.1
33.4
34
*
G04BD08
ATC
solifenacin; oral
11.2
33.3
37
37
N06BA07
ATC
modafinil; oral
69.2
32.8
37
6
R20.2
ICD-10 Finland
Paraesthesia of skin
5.4
32.6
76
174
G04BD09
ATC
trospium; oral
53.5
32.3
38
8
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.5
31.1
69
151
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.1
28.5
100
315
L04AG12
ATC
ofatumumab; parenteral
294.0
27.1
27
*
L03AB13
ATC
peginterferon beta-1a; parenteral
+∞
26.4
25
*
R4110
NOMESCO Finland
Physiotherapy
3.6
26.3
129
506
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.7
25.4
52
105
C10AC01
ATC
colestyramine; oral
9.0
24.8
32
39
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.2
23.1
53
118
TKC22
NOMESCO Finland
Catheterisation instruction
43.6
23.1
28
7
Z3226
NOMESCO Finland
Physiotherapist
3.6
22.1
90
309
UKC02
NOMESCO Finland
Cystoscopy
4.8
21.7
55
133
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
24.3
20.8
29
13
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
5.2
20.3
45
97
H48.1*G35
ICD-10 Finland
Retrobulbar neuritis in multiple sclerosis
+∞
20.0
19
*
L04AK02
ATC
teriflunomide; oral
212.4
19.8
20
*
Z3231
NOMESCO Finland
Registered nurse
3.0
19.7
123
543
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
6.4
19.1
33
56
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
32.2
18.6
24
8
Z2445
NOMESCO Finland
Psychologist
5.1
18.6
42
92
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
15.8
18.0
29
20
L04AA40
ATC
cladribine; oral
70.7
17.9
20
*
F02.89*G35
ICD-10 Finland
Dementia in multiple sclerosis
+∞
17.9
17
*
4AA23, ,
NOMESCO Finland
189.9
17.7
18
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
6.5
17.6
30
50
N03AE01
ATC
clonazepam; systemic
5.2
17.1
37
78
L04AA52
ATC
[U] ofatumumab; parenteral
+∞
16.8
16
*
H53.2
ICD-10 Finland
Diplopia
7.4
16.8
25
36
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
12.1
15.6
28
25
R4150
NOMESCO Finland
Neuropsychological rehabilitation
14.0
15.5
26
20
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.5
15.4
40
98
R4120
NOMESCO Finland
Occupational therapy
4.3
14.6
40
102
G04BD11
ATC
fesoterodine; oral
28.7
14.4
19
7
G04BD04
ATC
oxybutynin; oral, transdermal
5.8
14.3
27
50
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
44.6
14.2
17
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.7
13.9
34
79
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
55.9
13.9
16
*
N05CF01
ATC
zopiclone; oral
2.5
13.3
116
588
XKC03
NOMESCO Finland
Water cystometry
11.7
13.3
24
22
XCD10
NOMESCO Finland
Electrophysiological examination of eye
10.7
13.2
25
25
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
6.1
12.9
23
40
N03AX12
ATC
[U] gabapentin; oral
2.9
12.8
72
292
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
9.2
12.3
25
29
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.0
12.2
36
97
G04BD07
ATC
tolterodine; oral
9.5
12.0
24
27
G37.3
ICD-10 Finland
Acute transverse myelitis in demyelinating disease of central nervous system
+∞
11.5
11
*
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
124.2
11.5
12
*
L04AX09
ATC
diroximel fumarate; oral
124.2
11.5
12
*
N02BF01
ATC
gabapentin; oral
3.1
11.4
53
193
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
9.7
11.2
22
24
A28
ICPC
Limited function/disability NOS
3.6
10.8
38
116
G04CA02
ATC
tamsulosin; oral
3.8
10.8
35
101
3400A
ICD-9 Finland
Multiple sclerosis[SCLEROSIS MULTIPLEX (DISSEMINATA)]
62.1
10.7
12
*
TKC20
NOMESCO Finland
Catheterisation of bladder
5.2
10.4
22
45
Z2221
NOMESCO Finland
Medical doctor
2.2
9.7
117
667
SPAT1229
SPAT
Assessment of need for aid
5.0
9.7
21
44
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
22.5
9.4
13
6
J01EA01
ATC
trimethoprim; systemic
2.2
9.3
103
565
L28
ICPC
Limited function/disability (L)
2.8
9.1
50
199
H53.1
ICD-10 Finland
Subjective visual disturbances
3.1
9.1
39
135
N29
ICPC
Neurological sympt/complt other
8.3
9.0
19
24
N03AX16
ATC
[U] pregabalin
2.3
8.6
81
414
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.7
8.6
51
211
R33
ICD-10 Finland
Retention of urine
7.0
8.5
20
30
G04BE03
ATC
sildenafil; oral
+∞
8.4
8
*
A06AD11
ATC
lactulose; oral
3.1
8.3
36
125
R35
ICD-10 Finland
Polyuria
3.6
8.1
27
79
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.6
8.0
27
80
XKD03
NOMESCO Finland
Urethral pressure profilometry
11.2
7.9
14
13
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
15.5
7.8
12
8
G36.0
ICD-10 Finland
Neuromyelitis optica [Devic]
81.9
7.4
8
*
4AA36, ,
NOMESCO Finland
+∞
7.3
7
*
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
9.1
7.1
14
16
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
6.7
53
250
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
23.1
6.7
9
*
G04CA01
ATC
alfuzosin; oral
3.5
6.4
22
66
NA7CM
NOMESCO Finland
Spine and spinal cord extensive MRI examination with 3 Tesla magnet
+∞
6.3
6
*
L01BB04
ATC
cladribine; systemic
+∞
6.3
6
*
XCK10
NOMESCO Finland
Photography of fundus of eye
3.0
6.2
27
94
N06AX12
ATC
bupropion; oral
2.3
6.1
47
219
B02
ICD-10 Finland
Zoster [herpes zoster]
3.4
6.1
22
68
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
12.8
6.1
10
8
XX9CW
NOMESCO Finland
Submitting image material and/or investigation material to patient
12.8
6.1
10
8
N02BF02
ATC
pregabalin; oral
2.8
6.1
32
124
J01CA08
ATC
pivmecillinam; oral
1.8
6.1
165
1192

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
119
66
27.82
156.36
1.2
1.2
—
—
—
0
0
268
883
12.44
90.58
19.8
5.8
—
—
—
0
0
137
232
9.46
85.53
4.9
2.5
9.64
10.20
g/l
1.24
129
220
50
12
49.03
84.36
2.3
1.4
0.03
0.28
e9/l
—
11
7
304
1347
19.62
70.76
24.0
5.9
9.51
8.16
%
17.94
304
1287
303
1343
18.80
70.30
24.0
5.9
0.81
0.71
%
3.01
303
1271
303
1347
18.71
69.95
24.0
5.9
2.90
2.84
%
0.16
303
1284
304
1375
18.94
68.32
23.6
5.7
61.91
56.47
%
20.71
304
1331
305
1390
19.54
67.84
24.0
5.9
24.01
29.56
%
23.71
305
1343
194
628
6.16
59.82
5.1
2.3
0.06
0.22
e6/l
3.47
186
431
208
732
6.09
57.73
5.1
2.5
11.98
71.22
e6/l
1.81
201
528
42
27
17.71
49.46
2.4
2.2
49.02
45.48
%
0.63
42
27
223
922
5.49
48.53
6.5
3.1
13.91
39.03
e6/l
1.60
204
579
126
362
5.04
42.27
3.9
2.2
0.63
0.84
e6/l
0.50
81
169
60
86
8.32
41.32
1.3
1.3
—
—
—
0
0
35
23
16.93
40.56
1.1
1.1
1654.91
1609.70
miu/ml
0.06
35
23
115
326
4.91
38.83
1.5
1.6
—
—
—
0
0
249
1272
5.05
37.66
22.9
8.9
0.00
0.00
e9/l
0.47
236
1045
180
793
3.84
31.90
12.8
5.4
—
—
—
0
0
229
1186
4.13
31.76
5.2
2.8
6.42
6.18
ph
2.77
121
709
106
336
4.19
30.09
4.3
2.3
2.81
3.72
e6/l
0.51
61
144
234
1289
3.89
28.24
2.8
2.5
94.73
72.65
nmol/l
19.01
229
1226
253
1482
4.16
27.50
6.6
3.1
0.00
4.83
estimate
0.50
53
312
251
1465
4.10
27.36
6.5
3.1
0.00
0.00
estimate
0.50
52
309
253
1487
4.13
27.24
6.6
3.2
0.00
0.01
estimate
0.50
53
299
149
663
3.30
24.45
4.4
2.1
—
—
—
0
0
124
507
3.33
23.21
1.5
1.6
—
—
—
0
0
159
840
2.74
17.75
1.7
1.8
—
—
—
0
0
25
14
19.21
16.75
4.3
2.5
157.24
207.86
e6/l
0.28
25
14
27
21
13.90
15.98
1.1
1.0
1.05
0.51
ratio
4.03
17
12
60
204
3.38
14.54
3.6
1.8
—
—
—
0
0
25
21
12.79
14.34
4.0
2.9
52.63
46.95
%
—
16
8
27
51
5.68
13.97
1.5
2.2
2.58
2.95
index
0.10
12
22
17
6
29.76
13.09
2.1
3.5
8.59
7.50
%
—
17
6
18
8
23.71
13.04
2.3
2.8
19.67
25.00
%
—
18
8
32
76
4.56
12.77
1.1
1.1
13.24
13.62
e6/l
0.01
25
55
32
77
4.50
12.56
1.1
1.2
16.85
205.64
e6/l
1.08
26
59
16
8
20.94
11.24
1.0
1.0
6.66
5.58
mg/g
—
11
8
28
67
4.48
11.05
1.0
1.2
—
—
—
0
0
16
9
18.62
10.83
1.0
1.0
—
—
—
0
0
326
3005
+∞
10.77
18.1
12.2
63.19
68.56
umol/l
13.52
326
2982
54
208
2.91
10.46
8.5
4.8
0.00
0.20
%
—
9
44
54
209
2.90
10.37
8.6
4.5
0.30
0.96
%
—
10
48
134
793
2.17
10.19
14.7
4.3
—
—
—
0
0
20
39
5.40
9.97
1.2
1.1
—
—
—
0
0
161
1031
2.11
9.89
1.8
2.1
—
—
—
0
0
55
221
2.79
9.84
8.4
4.6
0.50
1.07
%
—
10
57
224
2702
0.45
9.31
3.0
3.5
1.19
1.24
mmol/l
0.57
213
2595
23
54
4.51
9.28
3.8
3.6
3.36
4.35
e9/l
1.71
23
54
62
275
2.55
9.09
2.9
2.2
1599.36
5480.63
u/l
—
9
113
51
214
2.64
8.35
10.6
5.0
0.00
0.17
%
—
6
42
188
1329
1.98
8.26
4.0
5.3
9.41
10.08
umol/l
0.78
182
1270
52
225
2.56
7.99
2.2
1.8
0.00
0.05
estimate
0.49
11
56
167
1144
1.94
7.94
7.2
2.9
0.00
0.05
estimate
1.63
51
271
249
2857
0.46
7.69
3.4
4.0
1.58
1.48
mmol/l
3.09
233
2762
252
2875
0.46
7.48
3.7
4.4
2.91
2.89
mmol/l
0.13
239
2783
155
1053
1.90
7.40
3.8
3.1
25.95
27.81
u/l
0.52
148
1006
298
2579
2.81
6.80
29.7
13.3
13.12
13.32
%
3.72
298
2560
23
69
3.51
6.69
3.9
3.2
61.22
59.42
%
0.35
23
69
33
125
2.82
6.55
2.5
1.8
0.00
0.02
estimate
0.49
12
49
253
2861
0.48
6.43
3.4
4.1
4.91
4.82
mmol/l
0.98
240
2774
130
888
1.77
5.72
5.7
2.6
0.00
0.03
estimate
1.34
49
257
115
762
1.79
5.58
8.9
3.3
0.00
0.01
estimate
0.80
53
300
102
1464
0.56
5.52
2.2
2.5
—
—
—
0
0
114
765
1.75
5.24
2.6
1.4
1.76
2.16
g/l
3.92
88
514
183
1402
1.70
5.15
3.6
4.1
6.18
6.29
mmol/l
0.38
172
1274
240
2027
1.70
4.24
5.0
6.9
67.88
72.85
u/l
2.22
230
1941
33
157
2.23
4.10
1.6
1.3
—
—
—
0
0
13
35
3.82
3.63
1.1
1.1
—
—
—
0
0
93
650
1.60
3.46
7.3
3.0
1.02
1.02
kg/l
0.25
72
417
51
308
1.78
3.26
2.3
2.4
5.02
6.04
umol/l
0.36
41
271
132
1012
1.51
3.21
3.3
4.1
38.78
37.69
g/l
1.58
124
972
37
608
0.56
2.86
3.9
4.1
6.92
10.18
mg/mmol
0.22
22
376
326
3188
+∞
2.82
36.2
17.3
259.47
264.75
e9/l
0.89
326
3156
37
601
0.57
2.73
3.0
3.5
35.61
61.17
mg/l
0.41
22
389
298
2772
1.87
2.64
9.5
10.4
3.89
3.91
mmol/l
0.70
292
2712
326
3192
+∞
2.63
36.2
17.3
5.66
6.71
e9/l
26.48
326
3154
326
3192
+∞
2.63
36.2
17.3
137.24
136.60
g/l
0.50
326
3177
326
3191
+∞
2.63
36.8
17.4
41.15
40.84
%
1.07
326
3176
326
3191
+∞
2.63
36.1
17.2
4.56
4.56
e12/l
0.00
326
3156
326
3191
+∞
2.63
36.0
17.1
30.28
30.07
pg
1.76
326
3176
326
3190
+∞
2.62
36.1
17.2
90.61
90.00
fl
2.04
326
3176
8
200
0.38
2.39
1.1
1.1
—
—
—
0
0
5
8
6.33
2.38
1.2
3.5
1.20
0.50
index
—
5
8
306
2898
1.91
2.13
11.7
10.7
21.47
18.91
mg/l
0.61
224
2289
36
228
1.65
1.98
8.7
3.0
—
—
—
0
0
44
632
0.65
1.93
1.3
1.3
2.04
9.13
u/ml
2.50
19
272
55
747
0.68
1.82
3.4
3.2
8.20
8.18
mmol/l
0.01
48
663
7
23
3.09
1.81
1.0
1.0
103.57
119.17
pmol/l
—
7
23
22
363
0.58
1.72
1.1
1.4
—
—
—
0
0
23
375
0.58
1.72
1.1
1.2
—
—
—
0
0
0
47
0.00
1.72
0.0
6.6
—
369.12
—
0
42
18
313
0.55
1.70
2.5
1.7
—
—
—
0
0
6
19
3.20
1.67
1.8
4.2
—
—
—
0
0
51
688
0.69
1.61
1.2
1.4
11.54
23.24
iu/ml
—
8
206
10
43
2.37
1.60
3.4
1.7
—
—
—
0
0
38
533
0.68
1.48
1.3
1.3
—
—
—
0
0
248
2642
0.74
1.44
2.8
3.8
5.58
5.64
mmol/l
0.40
236
2518
28
411
0.65
1.36
1.3
1.6
1219.96
992.26
mu/l
0.39
20
340
280
2648
1.41
1.34
31.6
13.7
333.77
333.13
g/l
0.77
280
2637
18
106
1.74
1.32
1.6
1.3
26.27
21.41
u/l
0.27
13
90
50
654
0.72
1.32
1.4
1.5
—
—
—
0
0
19
114
1.71
1.31
2.3
2.1
5.77
5.34
iu/l
—
10
46
73
899
0.76
1.28
2.0
2.0
—
—
—
0
0
11
202
0.53
1.27
1.3
1.6
—
—
—
0
0
16
92
1.78
1.27
1.2
1.2
—
—
—
0
0
17
100
1.74
1.26
1.1
3.0
—
—
—
0
0
33
231
1.48
1.23
8.8
6.8
105.67
104.97
mmol/l
0.47
33
231
11
197
0.54
1.18
1.3
1.5
—
—
—
0
0
37
499
0.71
1.17
1.8
2.5
85.70
77.28
ug/g
0.12
24
404
11
196
0.55
1.17
1.3
1.4
1.09
1.30
mm
—
6
141
5
20
2.52
1.15
2.0
1.3
31.60
32.75
pg
—
5
20
100
1169
0.79
1.15
1.6
1.8
1.39
1.40
mmol/l
0.03
87
1063
7
30
2.36
1.13
1.0
1.1
—
—
—
0
0
7
30
2.36
1.13
1.0
1.2
—
—
—
0
0
7
35
2.02
1.00
5.0
2.8
—
—
—
0
0
0
30
0.00
0.97
0.0
1.3
—
0.16
—
0
12
9
50
1.82
0.97
1.0
1.0
—
—
—
0
0
21
142
1.51
0.95
1.0
1.2
—
—
—
0
0
61
497
1.28
0.93
3.4
3.7
—
—
—
0
0
97
837
1.23
0.90
1.8
2.8
2.35
2.35
mmol/l
0.11
90
797
244
2564
0.81
0.89
3.2
4.6
35.78
37.22
mmol/mol
2.15
235
2485
39
302
1.33
0.86
1.2
1.2
—
—
—
0
0
17
248
0.67
0.84
1.2
1.1
—
—
—
0
0
17
247
0.67
0.83
1.9
5.6
0.98
1.01
mmol/l
0.30
17
226
156
1701
0.84
0.82
2.7
3.3
94.06
69.68
ug/l
0.51
149
1646
58
696
0.80
0.82
1.4
1.8
—
—
—
0
0
11
66
1.69
0.79
1.0
1.4
—
—
—
0
0
6
33
1.83
0.79
1.3
1.2
—
—
—
0
0
8
48
1.68
0.79
1.8
1.8
4.50
5.74
mmol/24h
—
8
41
5
99
0.50
0.79
1.0
1.3
—
—
—
0
0
121
1345
0.84
0.78
2.4
2.5
—
—
estimate
—
0
0
10
59
1.72
0.76
1.0
1.1
—
—
—
0
0
11
67
1.66
0.76
1.0
1.2
293.83
208.28
u/ml
—
6
41
14
93
1.53
0.70
2.7
1.6
—
—
—
0
0
18
127
1.44
0.69
1.9
2.7
69.07
77.71
e9/l
0.41
12
89
9
59
1.54
0.69
1.0
1.1
—
—
—
0
0
28
215
1.33
0.68
3.3
2.0
6.37
6.18
ph
0.59
15
130
113
1015
1.17
0.67
1.5
1.8
100.32
97.78
pmol/l
0.22
63
594
58
679
0.82
0.65
1.7
1.7
0.53
0.79
mg/l
1.10
46
508
17
234
0.71
0.65
1.1
1.2
—
—
—
0
0
27
209
1.32
0.62
1.3
1.4
118.20
251.41
miu/ml
—
10
105
108
1193
0.86
0.62
1.9
1.9
—
—
—
0
0
5
30
1.68
0.61
1.0
1.3
—
—
—
0
0
93
1036
0.86
0.60
1.4
1.7
—
—
—
0
0
57
662
0.83
0.60
2.2
2.5
—
—
—
0
0
48
403
1.22
0.59
1.8
2.8
554.95
445.82
ng/l
0.07
20
200
0
22
0.00
0.59
0.0
3.0
—
—
—
0
0
5
90
0.55
0.56
1.2
2.9
—
—
—
0
0
15
205
0.72
0.56
1.2
1.1
0.83
0.89
g/l
0.55
15
205
14
99
1.43
0.55
1.6
1.2
—
—
—
0
0
15
108
1.41
0.54
15.9
9.7
94.92
93.96
%
0.50
15
108
20
152
1.34
0.53
12.6
7.2
—
—
—
0
0
15
202
0.73
0.52
1.2
1.1
1.67
1.56
g/l
0.66
15
202
20
155
1.31
0.48
11.7
8.5
124.90
122.38
g/l
0.25
20
150
27
329
0.80
0.46
1.3
1.3
—
—
—
0
0
20
156
1.30
0.46
12.5
8.8
96.96
96.25
%
0.45
20
150
13
96
1.37
0.42
2.0
2.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
0.00
—
0
15
0
15
0.00
0.41
0.0
2.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.36
—
0
9
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
2.1
—
105.24
—
0
17
0
17
0.00
0.41
0.0
2.1
—
1.19
—
0
17
0
17
0.00
0.41
0.0
2.1
—
4.03
—
0
17
0
17
0.00
0.41
0.0
1.6
—
0.45
—
0
17
0
17
0.00
0.41
0.0
1.2
—
75.52
—
0
12
0
18
0.00
0.40
0.0
1.6
—
170.67
—
0
18
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
72
789
0.89
0.36
1.9
2.7
49.33
21.26
ng/l
0.58
33
344
6
41
1.47
0.36
1.3
1.6
57.17
63.39
%
—
6
41
32
372
0.85
0.36
1.3
1.3
13.58
23.63
iu/l
2.16
27
319
9
121
0.74
0.36
1.3
1.7
1.06
1.19
g/l
—
9
115
20
163
1.24
0.35
1.5
2.8
7.41
7.39
ph
—
8
92
12
91
1.33
0.34
1.6
2.3
24.33
24.09
mmol/l
0.14
12
91
42
371
1.15
0.33
1.7
2.1
16.97
15.45
umol/l
0.62
36
348
20
166
1.22
0.30
1.4
1.6
0.19
0.28
mg/l
—
10
71
10
75
1.34
0.30
2.5
4.6
36.93
37.01
°c
—
10
75
37
418
0.87
0.30
1.5
1.8
3.29
3.42
mmol/l
0.32
26
299
12
94
1.29
0.28
2.8
7.9
22.35
24.49
mmol/l
1.41
12
88
67
620
1.10
0.26
1.5
1.5
17.53
20.73
nmol/l
1.25
61
566
21
179
1.19
0.25
12.3
8.0
13.41
13.62
kpa
0.06
21
172
21
179
1.19
0.25
12.3
8.1
5.13
5.09
kpa
0.08
21
171
61
660
0.91
0.25
1.8
2.0
2.46
2.78
mg/l
0.40
48
593
20
170
1.19
0.25
12.8
8.4
1.02
0.73
mmol/l
0.13
12
133
55
505
1.11
0.25
1.4
1.4
384.44
499.81
titre
0.63
18
105
70
652
1.09
0.24
2.7
3.6
7.40
7.40
ph
0.09
41
447
12
97
1.25
0.23
5.9
8.1
16.38
16.47
%
0.05
12
92
21
242
0.86
0.23
6.3
1.6
—
—
—
0
0
51
469
1.10
0.23
1.3
1.6
540.00
51963466.83
pmol/l
1.07
46
433
15
178
0.84
0.22
1.2
1.3
—
—
—
0
0
17
144
1.19
0.22
3.1
3.7
78.18
74.12
ng/l
0.10
17
135
5
42
1.19
0.21
1.0
1.4
—
67.54
—
0
5
0
11
0.00
0.21
0.0
1.2
—
966.00
—
0
5
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
7.73
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
552.60
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
3.2
—
2291.67
—
0
12
5
43
1.17
0.21
1.2
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
4.7
—
8.73
—
0
13
0
13
0.00
0.21
0.0
1.3
—
27.62
—
0
13
279
2751
1.10
0.20
5.3
5.5
1.65
1.72
mu/l
0.59
270
2668
6
49
1.23
0.20
2.7
1.8
213.50
167.20
ug/l
—
6
44
83
872
0.94
0.18
2.6
7.0
1.01
1.07
inr
2.87
65
721
236
2400
0.94
0.17
4.5
4.7
14.65
14.30
pmol/l
1.47
222
2306
20
177
1.14
0.16
12.8
8.2
7.42
7.42
ph
0.04
11
99
20
177
1.14
0.16
6.6
2.3
—
—
—
0
0
11
92
1.20
0.16
1.6
2.2
0.61
0.63
%
0.08
11
92
22
245
0.89
0.16
6.1
1.7
—
—
—
0
0
8
72
1.11
0.16
1.9
5.4
1.88
1.70
%
—
8
66
15
130
1.16
0.16
1.9
1.7
0.42
5.18
u/ml
—
6
39
9
82
1.10
0.15
2.1
4.9
—
—
—
0
0
30
326
0.91
0.14
1.3
1.2
68.94
174.03
u/ml
—
10
138
35
324
1.09
0.14
1.3
1.5
—
—
—
0
0
22
243
0.90
0.14
6.1
1.7
—
—
—
0
0
90
865
1.06
0.14
1.3
1.3
0.50
2.09
u/ml
1.69
16
243
10
84
1.20
0.14
1.6
2.5
85.92
63.59
ng/l
—
10
76
38
354
1.08
0.14
1.3
1.2
—
—
—
0
0
22
242
0.90
0.13
6.1
1.7
—
—
—
0
0
18
161
1.12
0.13
1.2
1.2
—
1.15
—
0
10
36
339
1.07
0.10
1.3
1.3
—
—
—
0
0
21
227
0.92
0.09
6.2
1.7
—
—
—
0
0
21
195
1.08
0.08
2.0
2.2
0.64
0.61
ug/l
0.08
11
74
7
66
1.06
0.08
1.9
5.4
0.73
0.92
%
—
7
60
20
186
1.08
0.07
1.2
1.2
—
—
—
0
0
10
90
1.11
0.05
1.1
1.2
—
—
—
0
0
79
807
0.97
0.05
1.8
2.3
49.10
56.86
u/l
1.78
72
767
32
332
0.96
0.04
1.8
2.0
—
—
—
0
0
95
965
0.98
0.04
5.6
5.2
1.22
1.22
mmol/l
0.30
87
910
19
198
0.96
0.02
6.8
1.7
—
—
—
0
0
21
203
1.04
0.01
1.1
1.1
—
201.67
—
0
6
11
108
1.02
0.00
1.9
1.7
—
—
—
0
0
11
112
0.98
0.00
1.1
1.1
—
—
—
0
0
11
112
0.98
0.00
1.1
1.1
—
—
—
0
0
110
1102
1.00
0.00
5.7
5.9
1.22
1.21
mmol/l
1.03
99
965
12
117
1.03
0.00
7.4
6.3
25.49
24.79
mmol/l
0.40
12
117
13
125
1.04
0.00
1.1
1.1
—
—
—
0
0
11
106
1.04
0.00
4.7
2.0
—
—
—
0
0
304
3044
0.98
0.00
11.9
9.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
10.80
—
0
5
0
8
0.00
-0.00
0.0
1.5
—
56.88
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
11.80
—
0
5
9
92
0.98
-0.00
6.0
6.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
47.40
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
13.42
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
0.64
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
288.20
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.9
—
15.79
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
0.02
—
0
9
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
1.18
—
0
7
0
5
0.00
-0.00
0.0
3.0
—
17.02
—
0
5
0
8
0.00
-0.00
0.0
40.4
—
6.42
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
64.00
—
0
6
7
73
0.96
-0.00
1.3
1.2
—
—
—
0
0
6
67
0.89
-0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
0.02
—
0
9
5
53
0.94
-0.00
2.4
5.0
0.98
1.13
mmol/l
—
5
46
0
5
0.00
-0.00
0.0
1.6
—
40.80
—
0
5
0
8
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
38.25
—
0
8

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: MSMED_DIMETHYL_FUMARATE – Use of dimethyl fumarate

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).