Benign neoplasm: Vertebral column

CD2_BENIGN_VERTEB_COLUMN

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D16.6& Hospital discharge: ICD-9 — 2132 Hospital discharge: ICD-8 — 21301 Cause of death: ICD-10 — D16.6& Cause of death: ICD-9 — 2132 Cause of death: ICD-8 — 21301 2 out of 7 registries used, show all original rules.	101
4. Check minimum number of events None	101
5. Include endpoints None	101
6. Filter based on genotype QC (FinnGen only)	92

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D16
Name in latin: Neoplasma benignum columnae vertebralis

NAME	CD2_BENIGN_VERTEB_COLUMN
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D166
HD_ICD_9	2132
HD_ICD_8	21301
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D166
COD_ICD_9	2132
COD_ICD_8	21301
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Benign neoplasm: Vertebral column based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	92	47	45
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	53.58	50.66	56.63

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
95: Matched controls
950

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D16.6

ICD-10 Finland

Benign neoplasm: Vertebral column

+∞

97.3

21301

ICD-8 Finland

Benign neoplasm of bone and cartilage, Columnae vertebralis (sacro et coccyge exclusis)

+∞

13.9

D48.0

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage

33.9

9.7

NA2AD

NOMESCO Finland

Thoracic spine CT examination

86.6

7.5

2132A

ICD-9 Finland

Benign neoplasm of bone and articular cartilage, Vertebral column, excluding sacrum and coccyx

+∞

7.4

NK6CT

NOMESCO Finland

Bone biopsy with CT guidance

43.3

6.9

NA2CG

NOMESCO Finland

Thoracal spine extensive MRI examination with high intensity magnet

43.3

6.9

ABB00

NOMESCO Finland

Excision of lesion of spinal canal

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40761535) Cells panel - Urine sediment

3.11

3.63

5.8

3.5

—

(3048689) Calprotectin [Mass/mass] in Stool

106

2.26

2.50

1.6

2.4

148.52

97.25

ug/g

0.28

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.35

2.42

6.9

8.4

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

4.85

2.31

1.5

1.3

—

(46236952) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)/1.73 sq M

2.36

2.11

2.8

3.5

60.00

68.36

ml/min/173m2

—

(3000494) Fungus identified in Specimen by Culture

110

2.04

1.91

2.2

1.8

—

(40768804) Tissue Pathology biopsy report

336

1.72

1.79

2.6

2.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

113

1.98

1.78

1.5

1.7

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

137

1.90

1.76

1.3

1.00

7.40

u/ml

—

(40768797) Stomach Pathology biopsy report

132

1.87

1.64

1.5

1.2

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

119

1.86

1.53

1.5

1.7

—

(3023323) Follitropin [Units/volume] in Serum or Plasma

2.58

1.52

1.6

1.5

20.71

23.49

iu/l

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

2.84

1.46

1.2

1.5

—

2.27

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

152

1.68

1.24

1.5

1.3

11.80

35.19

iu/ml

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

2.72

1.23

1.4

1.3

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

2.39

1.20

1.3

1.5

—

(3020891) Body temperature

2.15

1.18

5.4

4.1

36.90

37.02

°c

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

412

1.51

1.16

6.1

9.6

1.20

1.21

mmol/l

0.53

352

(3044290) Cell count panel - Cerebral spinal fluid

2.34

1.04

1.0

1.2

—

(3010421) pH of Blood

2.34

1.04

3.8

3.2

7.41

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

2.34

1.04

1.8

2.7

9.46

12.77

mg/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

295

1.48

1.02

4.2

3.5

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.99

0.0

1.6

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.99

0.0

2.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.30

0.95

1.5

2.6

—

(3018418) pH of Serum or Plasma

262

1.46

0.94

3.6

4.5

7.39

0.07

177

(40758558) Short blood count panel - Blood

253

1.47

0.93

9.1

6.0

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.22

0.93

1.3

1.7

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

172

1.53

0.93

5.0

3.0

0.80

0.82

ug/l

0.04

112

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.99

0.91

2.0

1.5

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

221

1.45

0.84

6.2

4.9

21.07

21.67

0.06

108

(3001019) Free T4 and TSH panel - Serum or Plasma

1.93

0.83

1.7

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

382

1.40

0.83

3.1

—

estimate

—

(3029937) Albumin [Presence] in Urine by Test strip

259

1.42

0.81

7.8

3.9

0.00

estimate

-0.00

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.80

0.0

1.1

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.79

0.0

4.2

—

28.59

—

(3024928) Oxygen saturation in Venous blood

0.00

0.78

0.0

3.0

—

55.80

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

747

1.57

0.78

4.7

4.6

1.15

1.28

mmol/l

1.23

686

(3003327) Ova and parasites identified in Stool by Light microscopy

2.24

0.77

1.4

1.7

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

2.24

0.77

1.6

1.3

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.24

0.77

1.6

1.3

—

(3021589) Normoblasts [#/volume] in Blood

350

1.36

0.72

12.7

12.5

0.00

e9/l

0.49

271

(3034770) Mitochondria Ab [Titer] in Serum

1.90

0.69

1.0

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

460

1.34

0.68

6.5

4.0

0.00

estimate

-0.00

(3031040) Bacteria [#/volume] in Urine by Automated count

551

1.36

0.68

6.2

4.6

—

3998.57

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

811

1.64

0.67

17.3

16.7

19.48

22.83

mg/l

0.57

675

(3009261) Glucose [Presence] in Urine by Test strip

473

1.33

0.64

6.2

4.1

0.00

estimate

-0.00

(3000475) Leukocytes [#/volume] in Synovial fluid

0.00

0.61

0.0

1.3

—

7006.50

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.61

0.0

3.2

—

11.77

—

(3015736) pH of Urine

378

1.31

0.59

6.0

3.6

6.58

6.21

1.07

203

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

349

1.31

0.58

6.8

4.0

0.00

estimate

-0.00

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

152

1.40

0.58

3.0

3.4

2.25

0.96

e6/l

0.37

(3004588) Protein electrophoresis panel - Serum or Plasma

1.58

0.57

1.7

2.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

153

1.39

0.56

1.6

1.8

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

109

1.45

0.55

5.4

9.6

1.10

1.06

mmol/l

0.27

104

(3026008) Bacteria identified in Urine by Culture

247

1.31

0.53

5.5

3.4

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.45

0.53

1.8

1.4

—

(3035350) Ketones [Presence] in Urine by Test strip

471

1.28

0.53

6.5

4.0

0.07

0.00

estimate

0.47

(3030467) Casts [#/volume] in Urine by Automated count

238

1.31

0.53

3.4

3.5

0.19

0.32

e6/l

0.47

165

(40761536) Microorganisms panel - Urine sediment

1.42

0.52

5.4

4.2

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

678

1.33

0.51

20.9

20.2

13.61

13.71

0.29

673

(3002582) Erythrocytes [#/volume] in Urine

287

1.29

0.50

3.3

3.5

103.74

25.70

e6/l

0.60

213

(3019060) Gas panel - Arterial blood

1.53

0.49

3.4

14.7

—

(3007164) IgA [Mass/volume] in Serum or Plasma

185

1.32

0.48

1.8

1.4

2.44

2.63

g/l

0.17

111

(3019150) Specific gravity of Urine by Refractometry

196

1.30

0.45

8.1

3.9

1.02

kg/l

0.66

125

(3008898) HLA-B27 [Presence]

1.59

0.43

1.0

1.1

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

351

1.24

0.42

4.0

48.45

37.57

ng/l

0.23

242

(40760892) CBC W Ordered Manual Differential panel - Blood

198

1.28

0.42

7.4

5.7

—

(3045716) Anion gap in Serum or Plasma by calculation

0.00

0.41

0.0

2.0

—

10.13

—

(3011648) Oxygen content in Venous blood

0.00

0.41

0.0

2.0

—

10.01

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.41

0.0

1.3

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.6

—

0.15

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.41

0.0

1.3

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.41

0.0

1.2

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.41

0.0

1.2

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.40

0.0

1.1

—

7.65

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

363

1.23

0.39

2.1

2.2

102.91

97.60

pmol/l

0.38

181

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.39

0.0

3.9

—

3.90

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.39

0.0

1.2

—

3.94

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.36

0.39

2.3

1.6

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

1.41

0.39

1.0

1.2

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

493

1.22

0.38

10.7

10.4

4.38

4.07

e9/l

0.42

427

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.40

0.38

3.3

2.9

0.19

0.22

g/l

0.47

(40761511) CBC panel - Blood by Automated count

829

1.39

0.38

16.5

14.3

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.39

0.34

2.3

3.04

4.75

ug/l

—

(3018010) Neutrophils/Leukocytes in Blood

398

1.20

0.33

7.5

6.3

57.36

57.67

0.06

379

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

111

1.31

0.32

1.6

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

205

1.23

0.31

1.3

0.90

0.95

u/ml

—

(4035726) Immunohistochemistry procedure

1.35

0.31

1.5

1.3

—

(3018095) Leukocytes [#/volume] in Urine

321

1.20

0.31

3.9

4.3

206.05

51.69

e6/l

0.36

222

(3014576) Chloride [Moles/volume] in Serum or Plasma

123

1.26

0.27

6.9

7.7

104.40

104.23

mmol/l

0.06

123

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

648

1.17

0.24

8.8

9.0

73.86

78.87

u/l

0.55

610

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.37

0.24

2.0

1.8

—

(3013115) Eosinophils [#/volume] in Blood

457

1.15

0.23

7.1

6.7

0.16

0.19

e9/l

0.90

409

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

101

0.77

0.22

1.3

2.2

1.31

1.35

—

(40768443) Skin Pathology biopsy report

1.20

0.22

5.4

1.2

—

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

8.7

—

10.98

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.9

—

231.36

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.21

0.0

1.4

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.3

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.9

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.5

—

(3000991) Gas panel - Venous blood

1.28

0.21

9.6

10.5

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3051014) Leukocytes [#/area] in Urine sediment by Automated count

0.00

0.21

0.0

2.4

—

4.40

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.21

0.0

1.5

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

350

1.14

0.21

2.0

2.1

1.38

1.34

mmol/l

0.09

296

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.5

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.1

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

786

1.21

0.20

4.9

5.2

5.72

5.97

mmol/l

1.09

721

(3023368) Bacteria identified in Blood by Culture

234

1.15

0.19

4.1

4.6

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.25

0.19

4.6

2.5

0.66

0.64

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.25

0.19

4.6

2.5

0.93

1.32

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

151

0.84

0.17

2.3

1.8

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

188

1.15

0.16

2.8

1.8

6.47

1.35

mg/l

0.54

151

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

140

1.17

0.16

3.1

3.5

0.83

2.79

e6/l

—

(3042936) Bacteria identified in Isolate by Culture

131

1.17

0.15

1.9

2.4

—

(3002032) Base excess in Venous blood by calculation

1.21

0.15

7.0

4.6

3.14

1.40

mmol/l

0.62

(3007853) Bacteria identified in Skin by Aerobe culture

103

1.19

0.14

3.2

1.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.83

0.14

1.6

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.83

0.14

4.0

3.4

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

148

0.86

0.13

8.9

3.9

0.82

mmol/l

0.01

140

(3002256) Pathology report gross observation

104

1.18

0.13

1.1

1.3

—

(3019198) Lymphocytes [#/volume] in Blood

448

1.10

0.13

7.2

6.5

1.82

1.88

e9/l

0.18

401

(3020682) Albumin/Creatinine [Ratio] in Urine

272

1.10

0.10

3.7

4.3

4.65

10.73

mg/mmol

1.15

175

(42870588) Differential panel, method unspecified - Blood

282

1.09

0.10

6.7

6.3

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.04

0.09

1.0

1.1

—

(1002224) Polysomnography panel

1.04

0.09

1.0

1.1

—

(1761868) Lipid panel - Serum or Plasma

327

0.92

0.09

3.6

3.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

107

1.14

0.09

1.5

1.7

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.10

0.08

6.1

7.7

27.07

24.88

mmol/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.05

0.08

1.6

1.9

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.85

0.08

1.3

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.04

0.07

2.3

2.0

—

(36660697) Celiac disease serology panel - Serum

1.03

0.07

1.3

1.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

193

0.92

0.07

3.9

2.8

—

(3000492) Spirometry study

0.85

0.07

1.8

1.4

—

(3044640) Blood type and Crossmatch panel - Blood

257

1.07

0.06

3.5

2.9

—

(3003694) ABO and Rh group [Type] in Blood

221

0.94

0.05

1.3

1.4

—

(3012516) Albumin [Mass/volume] in Urine

269

1.06

0.04

3.4

3.6

20.92

64.00

mg/l

2.19

180

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

529

1.05

0.04

3.0

3.1

—

(3001604) Monocytes [#/volume] in Blood

440

1.04

0.03

7.3

6.4

0.51

0.58

e9/l

1.75

383

(3022145) Colonoscopy Study observation

1.08

0.02

1.8

1.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

257

0.96

0.01

4.2

3.7

0.00

0.01

estimate

0.49

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

153

0.98

0.00

1.4

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

129

1.01

0.00

1.5

1.7

—

(3006315) Basophils [#/volume] in Blood

442

0.99

0.00

7.5

6.4

0.04

e9/l

0.48

383

(3020013) Alkaline phosphatase.intestinal [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.6

—

13.00

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.4

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.4

—

126.01

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.0

1.0

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.6

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

3.0

—

4.69

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3009876) Amylase isoenzyme 3 panel - Serum or Plasma

0.00

0.0

1.2

—

(3014271) Vancomycin [Susceptibility]

0.00

0.0

2.0

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.6

—

(3025941) Bacteria identified in Stool by Culture

0.94

0.00

1.0

1.2

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

2.0

—

254.40

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

0.0

11.6

—

0.63

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.4

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.0

1.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.94

0.00

2.5

2.1

—

(3002619) Bacteria identified in Specimen by Culture

0.00

0.0

1.4

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.0

—

6.23

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

3.0

—

9.30

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(3022493) Free Hemoglobin [Mass/volume] in Plasma

0.00

0.0

1.0

—

96.40

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.6

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.5

—

(21494755) Public health laboratory ask at order entry panel

1.01

-0.00

1.2

1.3

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.02

-0.00

1.2

1.1

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.7

—

58.50

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.2

—

30.80

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.92

-0.00

2.7

1.7

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

10.8

—

1440.00

—

(3009343) pH of Capillary blood

0.85

-0.00

1.6

3.1

7.45

7.42

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.3

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.4

—

30.26

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

266.78

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.6

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

8.7

—

863.67

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_VERTEB_COLUMN – Benign neoplasm: Vertebral column

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R14

FinnGen R13 + FinRegistry

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Benign neoplasm: Vertebral column

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Benign neoplasm: Vertebral column (CD2_BENIGN_VERTEB_COLUMN)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints