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Colitis due to radiation

COLITRAD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K52.0
  • Cause of death: ICD-10 K52.0

2 out of 7 registries used, show all original rules.

424

4. Check minimum number of events

None

424

5. Include endpoints

None

424

6. Filter based on genotype QC (FinnGen only)

380

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K52
Name in latin
Gastroenteritis e radiatione

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 380 114 266
Unadjusted period prevalence (%) 0.10 0.04 0.12
Median age at first event (years) 70.06 62.22 73.41

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
389
Matched controls
3890
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
307.7
388
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
11.8
137.9
227
414
A07EC02
ATC
mesalazine; oral, rectal
49.2
137.5
82
21
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
11.6
136.3
222
399
116
Kela drug reimbursment
Prostate cancer
12.3
130.5
172
235
A07EA02
ATC
hydrocortisone; rectal
74.7
124.8
68
11
K62.7
ICD-10 Finland
Radiation proctitis
54.7
117.5
68
15
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
12.1
111.7
137
167
UJF32
NOMESCO Finland
Coloscopy
8.7
101.0
257
711
L02AE02
ATC
leuprorelin; implant, parenteral
10.6
94.5
125
166
Y77
ICPC
Malignant neoplasm prostate
9.2
60.1
82
110
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
23.5
59.3
44
21
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
9.5
59.2
78
100
A07EA06
ATC
budesonide; oral, local oral
22.4
58.2
44
22
L02BB03
ATC
bicalutamide; oral
9.1
56.4
77
103
WF002
NOMESCO Finland
Radical radiotherapy
7.2
54.9
96
170
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
6.8
45.2
80
142
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
8.7
38.3
52
68
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
4.7
33.5
91
235
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
10.2
33.2
39
42
TKE00
NOMESCO Finland
Needle biopsy of prostate
5.5
32.3
71
153
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
31.7
30
*
C10AC01
ATC
colestyramine; oral
10.8
29.6
33
33
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
43.9
29.5
36
9
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
314.3
29.2
29
*
JFA55
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in colon
35.9
28.3
36
11
WZC00
NOMESCO Finland
Treatment plan or consultation
3.2
27.9
199
963
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
7.8
27.7
40
56
XKD00
NOMESCO Finland
Uroflowmetry
3.3
27.6
155
651
ZX090
NOMESCO Finland
Other technic of radiotherapy
7.1
26.6
42
65
XX3DW
NOMESCO Finland
Time consuming IT work
3.9
26.1
94
296
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.3
25.4
132
526
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
4.2
24.9
77
217
J01MA02
ATC
ciprofloxacin; systemic
3.0
24.7
227
1241
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
40.4
24.3
30
8
UKC02
NOMESCO Finland
Cystoscopy
3.1
24.1
140
593
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
44.6
24.0
29
7
A03FA01
ATC
metoclopramide; systemic, rectal
3.1
22.8
133
562
A07DA03
ATC
loperamide; oral
7.0
22.6
36
56
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
7.2
22.5
35
53
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
6.8
21.4
35
56
K51.5
ICD-10 Finland
Left sided colitis
+∞
21.0
20
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
6.6
21.0
35
57
D16
ICPC
Rectal bleeding
7.4
20.7
31
45
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
20.4
177
914
A06AC01
ATC
ispaghula (psylla seeds); oral
2.8
19.7
144
679
ZX070
NOMESCO Finland
Intensity modified radiotherapy
7.4
19.4
29
42
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
19.0
159
801
WF003
NOMESCO Finland
Adjuvant radiotherapy
6.1
18.9
34
60
UJF30
NOMESCO Finland
Ileoscopy through colon
3.7
18.6
65
198
128
Kela drug reimbursment
Cancers of female genital organs
23.1
18.4
26
12
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
18.3
251
1592
R31
ICD-10 Finland
Unspecified haematuria
3.0
18.2
99
396
JN4BD
NOMESCO Finland
Extensive body CT
3.3
18.2
82
294
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.6
17.7
66
210
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
7.8
17.6
25
34
XJH00
NOMESCO Finland
Transanal ultrasonography
3.5
17.5
69
227
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
16.0
157
839
JGA28
NOMESCO Finland
Endoscopic contact coagulation in rectum
39.8
15.5
19
5
ZX080
NOMESCO Finland
Image guided radiotherapy
6.4
15.3
26
43
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
5.3
15.3
32
65
C05AA08
ATC
fluocortolone; rectal, topical
3.0
15.0
76
290
JN4AD
NOMESCO Finland
Body CT examination
2.9
14.5
80
320
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
14.3
84
347
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.0
14.3
32
69
UJG02
NOMESCO Finland
Proctoscopy
6.7
14.3
23
36
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
10.7
14.2
27
27
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.5
14.1
111
530
UJH02
NOMESCO Finland
Anoscopy
4.9
14.0
32
70
WB223
NOMESCO Finland
Demanding adjuvant hormone therapy of malignancy
31.3
14.0
18
6
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
+∞
13.6
13
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
13.6
13
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.0
13.3
64
236
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
15.8
13.2
21
14
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
6.4
13.1
22
36
L02AE03
ATC
goserelin; implant
10.6
12.7
24
24
K59.1
ICD-10 Finland
Functional diarrhoea
4.1
12.4
35
91
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
11.5
11
*
JGA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in rectum
123.5
11.5
12
*
K51.8
ICD-10 Finland
Other ulcerative colitis
123.5
11.5
12
*
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
3.2
11.5
48
163
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
11.2
105
536
G04CA02
ATC
tamsulosin; oral
2.1
11.1
183
1168
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.1
10.8
48
169
WF049
NOMESCO Finland
Radiotherapy of metastasis
3.9
10.5
32
88
L04AX01
ATC
azathioprine; systemic
8.6
10.5
22
27
JGA35
NOMESCO Finland
Other endoscopic haemostatic procedure in rectum
+∞
10.5
10
*
H02AB02
ATC
dexamethasone; systemic
2.7
10.5
64
268
L02BX03
ATC
abiraterone; oral
12.5
10.4
18
15
ZX120
NOMESCO Finland
Intravenous
2.8
10.4
57
225
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.4
10.3
80
376
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
10.2
74
337
LCD30
NOMESCO Finland
Radical hysterectomy
41.2
10.0
12
*
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.1
10.0
43
148
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.0
10.0
29
77
ZXC20
NOMESCO Finland
Use of chemical agents
5.1
9.9
21
43
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.0
9.9
184
1212
N02AX02
ATC
tramadol; systemic, rectal
2.0
9.7
192
1287
K50.9
ICD-10 Finland
Crohn disease, unspecified
56.4
9.7
11
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
4.6
9.7
23
52
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
9.5
58
242
8380/3-C54.9
ICD-O-3
Endometrioid adenocarcinoma, NOS, of corpus uteri
30.9
9.5
12
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
+∞
9.4
9
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
9.4
67
302
163
Kela drug reimbursment
Abiraterone and enzalutamide
9.4
9.1
18
20
K92.1
ICD-10 Finland
Melaena
3.0
9.1
42
151
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
9.0
72
341
A02BC05
ATC
esomeprazole; systemic
1.9
9.0
163
1054
L02BX02
ATC
degarelix; parenteral
7.1
9.0
21
31
H02AB06
ATC
prednisolone; systemic
1.9
9.0
201
1395
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
6.7
8.6
21
33
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.9
8.6
26
71
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
8.4
8
*
L02BB04
ATC
enzalutamide; oral
9.8
8.4
16
17
N02AA05
ATC
oxycodone; systemic
2.0
8.3
109
627
R50.9
ICD-10 Finland
Fever, unspecified
2.2
8.2
76
382
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.8
8.2
42
160
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
8.2
108
623
N30.4
ICD-10 Finland
Irradiation cystitis
22.6
8.1
11
5
SPAT1263
SPAT
Sampling
1.9
8.0
170
1146
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.7
8.0
46
186
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
8.0
174
1183
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
4.6
8.0
19
43
G03HA01
ATC
cyproterone; systemic
8.0
8.0
17
22
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.2
7.9
21
52
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
8.7
7.9
16
19
P01AB01
ATC
metronidazole; oral, rectal
1.9
7.9
147
951
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
7.8
73
368
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
45.9
7.7
9
*
B01AB05
ATC
enoxaparin; parenteral
1.9
7.7
141
907
ZXD05
NOMESCO Finland
Urgent procedure
1.9
7.6
131
823
352
Kela drug reimbursment
Abiraterone and enzalutamide
9.1
7.6
15
17
KE002
NOMESCO Finland
Radical radiotherapy of prostata and seminal vesicles
25.6
7.6
10
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
7.5
37
138
A04AA01
ATC
ondansetron; systemic, rectal
2.7
7.5
42
168
J01EA01
ATC
trimethoprim; systemic
2.0
7.4
100
579
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.8
7.4
38
145
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
7.3
7
*
L03AA13
ATC
pegfilgrastim; parenteral
3.3
7.3
27
85
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.2
7.2
68
344
WX704
NOMESCO Finland
Intubation
2.7
7.2
39
153
JFB00
NOMESCO Finland
Partial resection of small intestine
6.8
7.2
17
26
N02BE01
ATC
paracetamol; systemic, rectal
2.5
7.1
348
3018
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.8
7.1
22
61
U06
ICPC
Haematuria
3.5
7.1
24
71
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
3.1
7.1
29
97
J01DB01
ATC
cefalexin; oral
2.0
7.0
310
2579
ZXC96
NOMESCO Finland
Robot assisted procedure
4.1
7.0
19
48
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
6.9
66
335
A02BA02
ATC
ranitidine; systemic
1.9
6.9
95
553
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.2
6.9
27
88
G04BD08
ATC
solifenacin; oral
2.6
6.9
41
169
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
6.8
63
317
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
6.7
111
685
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
4.1
6.7
18
45
-, ,
ICD-10 Finland
5.7
6.7
18
33
K56.7
ICD-10 Finland
Ileus, unspecified
6.1
6.7
17
29
A02BC01
ATC
omeprazole; systemic
1.8
6.6
121
770
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
3.0
6.6
29
101
K56.0
ICD-10 Finland
Paralytic ileus
10.3
6.6
12
12
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
3.1
6.6
28
96
D40.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Prostate
4.1
6.5
18
46
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
71.0
6.4
7
*
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
71.0
6.4
7
*
C54.9
ICD-10 Finland
Malignant neoplasm: Corpus uteri, unspecified
71.0
6.4
7
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
3.9
6.4
19
51
C07AB07
ATC
bisoprolol; oral
1.7
6.4
229
1761
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.3
6.4
24
76
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
+∞
6.3
6
*
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
6.3
6
*
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
+∞
6.3
6
*
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
27.1
6.2
8
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
6.2
41
177
OAB50, ,
SPAT
2.4
6.2
42
184
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
6.2
72
394
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
3.7
6.1
19
53
JAH00
NOMESCO Finland
Laparotomy
3.5
6.1
21
63
G03CA04
ATC
estriol; systemic, vaginal
3.2
6.0
24
79

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
104
334
3.89
28.25
1.5
1.3
—
—
—
0
0
88
256
4.15
27.40
3.4
1.3
191.38
123.53
ug/g
0.85
71
195
200
1002
3.05
25.88
3.0
2.2
3.07
2.91
mg/l
0.43
185
861
56
140
4.50
21.03
1.6
1.2
—
—
—
0
0
257
1583
2.84
21.03
7.5
5.1
33.75
34.51
g/l
1.21
239
1487
85
316
3.16
17.74
2.6
2.3
8.03
12.33
nmol/l
3.59
75
265
272
1839
2.59
16.59
10.2
7.1
10.86
12.55
umol/l
2.21
266
1756
230
1461
2.40
15.77
4.4
3.0
174.24
153.90
ug/l
0.25
217
1342
132
669
2.47
14.90
3.3
2.6
12.64
12.34
umol/l
0.08
127
616
264
1810
2.43
14.82
10.0
7.4
1.20
1.21
mmol/l
0.23
227
1553
267
1848
2.42
14.54
13.6
9.7
4.22
4.33
e9/l
0.29
249
1596
244
1629
2.34
14.38
9.4
6.7
1.20
1.21
mmol/l
0.23
235
1494
124
622
2.46
14.22
3.1
2.6
2.21
2.20
g/l
0.04
119
569
248
1684
2.30
13.80
7.7
5.7
1.47
1.91
e9/l
5.04
231
1476
42
116
3.94
13.70
1.2
1.1
—
—
—
0
0
250
1706
2.30
13.70
7.7
5.8
0.18
0.20
e9/l
1.56
229
1469
325
2503
2.81
13.43
15.2
8.5
80.54
83.51
u/l
0.64
312
2360
179
1077
2.23
13.23
3.7
2.5
56.59
60.36
u/l
0.37
168
1003
244
1665
2.25
13.14
7.6
5.6
0.04
0.04
e9/l
0.71
224
1415
243
1657
2.24
13.09
7.6
5.6
0.60
0.63
e9/l
0.89
221
1402
115
577
2.41
13.03
3.2
2.6
22.84
22.23
%
0.12
109
534
227
1535
2.15
12.11
8.1
5.9
9.56
9.22
%
0.85
216
1433
229
1573
2.11
11.49
4.0
3.0
—
—
estimate
—
0
0
227
1556
2.10
11.43
8.2
5.9
22.94
25.57
%
2.76
219
1467
224
1528
2.10
11.42
8.0
5.7
60.92
58.79
%
1.87
216
1454
178
1117
2.09
11.34
7.4
5.6
—
—
—
0
0
224
1531
2.09
11.33
7.8
5.8
0.65
0.62
%
0.28
213
1429
223
1531
2.07
11.03
7.9
5.8
2.78
2.79
%
0.03
212
1428
187
1208
2.06
10.89
4.6
3.6
2.34
2.34
mmol/l
0.22
164
1085
182
1165
2.06
10.86
6.2
4.6
—
—
—
0
0
242
1721
2.07
10.76
5.6
4.1
0.00
4.11
estimate
0.50
53
396
97
494
2.28
10.36
8.2
7.6
1.29
0.99
mmol/l
0.29
74
411
97
496
2.27
10.25
8.2
7.6
7.41
7.41
ph
0.20
68
300
227
1597
2.01
10.17
2.7
2.3
88.36
93.76
pmol/l
1.18
157
877
123
697
2.12
10.03
2.1
1.8
1162.76
1196.82
nmol/l
0.17
105
524
199
1348
1.98
9.82
5.0
3.7
6.31
6.21
ph
0.59
116
729
273
2067
2.08
9.77
7.3
5.4
6.85
6.89
mmol/l
0.10
258
1971
85
420
2.31
9.70
4.1
4.5
3.54
38.19
ug/l
1.17
73
355
29
79
3.89
9.62
1.6
1.2
—
—
—
0
0
246
1804
1.99
9.51
18.2
17.8
1.29
1.35
inr
0.91
211
1527
239
1736
1.98
9.49
5.6
4.2
0.12
0.83
estimate
0.41
57
367
154
972
1.97
9.18
10.9
6.4
—
—
—
0
0
100
543
2.13
9.00
2.4
1.9
—
—
—
0
0
167
1093
1.93
8.87
6.2
4.6
7.39
7.40
ph
0.60
128
797
112
642
2.05
8.69
6.1
3.2
0.79
0.82
mmol/l
1.56
105
609
59
263
2.47
8.42
4.2
4.3
—
—
—
0
0
163
1076
1.89
8.30
5.3
3.3
—
—
—
0
0
170
1138
1.88
8.28
1.9
1.8
16.97
20.13
nmol/l
2.49
151
939
230
1698
1.87
8.17
5.5
4.1
0.00
0.00
estimate
-0.00
56
392
90
499
2.05
7.54
2.9
2.6
1.86
1.73
%
0.55
84
444
177
1226
1.81
7.53
5.1
3.6
21.44
135.73
e6/l
1.44
141
948
27
84
3.38
7.39
1.6
1.4
297.15
290.80
ug/g
0.06
20
50
189
1346
1.79
7.24
5.6
4.2
109.36
148.54
e6/l
0.20
148
977
120
746
1.88
7.17
6.3
4.5
1.02
1.02
kg/l
0.49
98
493
155
1062
1.76
6.63
5.1
3.5
0.53
0.45
e6/l
0.19
123
793
163
1140
1.74
6.44
3.7
2.5
—
—
—
0
0
197
1454
1.72
6.40
5.1
4.3
29.42
48.56
ng/l
3.02
152
1150
110
688
1.83
6.34
2.3
1.7
1.64
1.56
mg/l
0.06
89
549
155
1090
1.70
5.88
2.4
2.2
171.64
244.74
u/l
1.37
142
1024
119
778
1.76
5.86
1.9
1.8
404.41
8948635.96
pmol/l
0.50
100
637
187
1387
1.67
5.77
3.0
2.3
74.91
78.02
nmol/l
0.87
172
1216
29
110
2.77
5.71
1.3
1.2
—
—
—
0
0
343
3026
2.13
5.60
35.2
19.2
29.46
28.04
mg/l
0.30
308
2572
129
873
1.71
5.58
4.1
2.7
6.72
4.35
e6/l
0.99
120
791
236
1883
1.64
5.29
4.7
3.4
49.72
56.57
u/l
0.80
228
1756
96
607
1.77
5.24
1.5
1.2
2.22
1.39
u/ml
0.23
25
151
68
391
1.90
5.02
2.6
2.7
68.34
65.28
e9/l
0.28
51
295
62
347
1.94
4.96
1.7
1.3
257.14
543.08
titre
2.18
14
78
69
401
1.88
4.93
3.2
3.3
4.72
9.07
umol/l
4.27
58
355
140
997
1.63
4.87
6.3
4.1
0.00
0.01
estimate
0.50
41
343
114
771
1.68
4.84
3.9
3.2
554.74
558.31
mosm/kgh2o
0.07
100
673
42
206
2.16
4.79
2.3
2.9
—
—
—
0
0
167
1247
1.59
4.75
2.6
2.3
—
—
—
0
0
96
625
1.71
4.68
4.0
3.4
1.34
1.50
e6/l
0.08
60
337
171
1288
1.58
4.67
6.0
4.2
0.00
0.04
estimate
1.47
46
319
60
340
1.90
4.62
2.9
2.5
5.25
8.25
ug/l
1.18
51
301
221
1770
1.58
4.59
12.6
6.2
6.73
3.81
ug/l
0.56
202
1544
88
562
1.73
4.59
1.9
1.4
2.76
2.77
g/l
0.01
57
319
54
305
1.89
4.20
3.1
4.4
1.40
0.92
%
0.44
20
102
64
385
1.79
4.08
5.6
2.9
3.87
5.32
e9/l
1.33
55
328
69
426
1.75
4.03
1.3
1.3
—
—
—
0
0
54
313
1.84
3.88
3.3
2.3
33.82
31.70
u/l
0.20
40
262
8
11
7.40
3.87
1.3
1.1
38.18
39.66
g/l
—
8
11
264
2250
1.54
3.80
5.4
4.7
—
0.40
—
0
5
169
1313
1.51
3.79
3.9
3.4
2272.49
1811.86
ng/l
0.34
150
1157
75
485
1.68
3.70
1.4
1.3
22.95
33.73
iu/ml
0.62
26
152
52
303
1.83
3.68
1.6
1.4
—
—
—
0
0
338
3068
1.78
3.63
30.9
17.4
—
—
—
0
0
35
179
2.05
3.62
3.1
2.6
—
—
—
0
0
37
195
1.99
3.53
2.1
2.0
2.83
3.35
ug/l
0.09
32
167
18
69
2.69
3.52
1.4
1.2
—
—
—
0
0
344
3145
1.81
3.51
40.7
23.5
138.80
139.64
mmol/l
6.69
334
3082
71
459
1.67
3.50
1.3
1.3
1.23
13.85
u/ml
2.58
18
158
344
3147
1.80
3.47
41.2
23.8
4.04
4.03
mmol/l
0.55
334
3080
181
1447
1.47
3.43
17.5
12.7
0.00
0.00
e9/l
0.12
156
1174
95
667
1.56
3.34
5.1
5.0
—
—
—
0
0
49
289
1.80
3.34
2.8
4.5
0.19
0.13
%
0.16
16
85
38
207
1.93
3.31
1.3
1.2
—
—
—
0
0
104
748
1.53
3.28
3.9
3.2
2.46
2.46
mmol/l
0.08
89
672
6
7
8.68
3.27
1.0
1.0
—
—
—
0
0
49
292
1.78
3.23
2.7
4.8
0.06
0.19
%
0.49
16
79
103
743
1.53
3.20
5.4
4.2
204.38
303.40
ng/l
0.38
93
639
346
3187
1.77
3.18
45.1
25.8
89.31
86.55
umol/l
0.47
337
3143
261
2259
1.47
3.16
4.1
3.9
14.99
15.01
pmol/l
0.04
231
2012
82
572
1.55
2.95
9.8
7.0
104.61
104.54
mmol/l
0.04
82
572
47
285
1.74
2.93
2.7
4.4
0.56
0.47
%
0.15
18
90
348
3226
1.75
2.92
52.4
28.9
236.36
235.45
e9/l
0.09
340
3162
348
3226
1.75
2.92
52.2
28.8
91.75
91.79
fl
0.04
341
3190
348
3227
1.74
2.90
52.1
28.8
30.33
30.48
pg
0.74
341
3190
348
3227
1.74
2.90
53.7
29.5
37.19
39.80
%
12.12
341
3187
348
3227
1.74
2.90
52.4
28.9
6.48
7.00
e9/l
4.82
339
3150
348
3227
1.74
2.90
52.8
29.1
124.36
133.41
g/l
20.49
342
3187
348
3227
1.74
2.90
52.2
28.9
4.14
4.42
e12/l
18.37
337
3149
308
2778
1.52
2.86
5.4
5.0
2.01
2.00
mu/l
0.07
277
2490
14
53
2.70
2.82
1.6
3.0
—
—
—
0
0
5
6
8.42
2.75
2.6
1.3
—
—
—
0
0
45
275
1.72
2.74
3.2
3.7
7.41
7.42
ph
0.45
39
229
12
40
3.06
2.72
1.8
2.0
—
—
—
0
0
133
1040
1.42
2.69
4.7
3.5
0.83
0.82
ug/l
0.00
96
724
44
272
1.70
2.57
2.8
2.8
—
—
—
0
0
15
62
2.48
2.57
1.9
1.4
—
—
—
0
0
29
158
1.90
2.56
2.8
3.5
21.29
2244.06
u/ml
1.29
24
137
8
21
3.87
2.47
1.0
1.8
45.05
30.18
%
—
8
21
61
415
1.56
2.45
1.7
1.4
—
—
—
0
0
66
458
1.53
2.43
1.3
1.3
—
—
—
0
0
61
420
1.54
2.32
1.9
1.7
—
—
—
0
0
24
127
1.95
2.31
1.6
3.4
172.88
232.61
mg/l
—
8
54
337
3137
1.56
2.31
20.1
12.8
23.16
24.65
u/l
1.15
329
3039
22
115
1.97
2.20
2.3
2.2
127.53
126.60
g/l
0.05
17
91
8
24
3.38
2.19
1.0
1.2
—
—
—
0
0
118
933
1.38
2.17
3.8
3.2
359.41
365.07
umol/l
0.22
104
800
11
42
2.67
2.16
2.1
2.1
0.65
1.34
g/l
0.93
11
33
56
386
1.53
2.13
6.0
3.7
1.38
1.73
mmol/l
0.12
50
323
263
2358
1.36
2.09
45.8
25.8
330.14
331.71
g/l
1.93
257
2347
9
31
2.95
2.08
1.2
1.3
26.37
23.11
ng/l
—
9
31
110
867
1.37
2.06
1.5
1.4
—
—
—
0
0
8
26
3.12
2.02
2.4
1.8
—
—
—
0
0
57
401
1.49
1.98
5.9
3.6
7.37
7.38
ph
0.48
42
236
56
393
1.50
1.96
6.0
3.7
5.84
5.74
kpa
0.18
56
378
15
71
2.16
1.95
1.2
1.2
—
—
—
0
0
5
11
4.59
1.94
1.0
1.0
—
—
—
0
0
48
329
1.52
1.88
4.6
3.6
7.38
7.35
ph
0.48
42
227
6
18
3.37
1.75
1.0
1.1
—
—
—
0
0
30
187
1.65
1.75
3.0
4.0
—
—
—
0
0
11
50
2.23
1.58
1.6
1.4
—
—
—
0
0
11
50
2.23
1.58
1.6
1.4
—
—
—
0
0
11
50
2.23
1.58
1.6
1.4
—
—
—
0
0
11
50
2.23
1.58
1.6
1.4
—
—
—
0
0
21
123
1.75
1.54
4.5
4.1
16.16
3.56
ratio
0.40
14
69
17
93
1.87
1.54
3.2
3.6
2.00
2.18
index
—
8
62
5
127
0.39
1.52
1.0
1.4
—
—
—
0
0
6
21
2.89
1.51
1.0
1.2
114.00
90.43
pmol/l
—
6
21
12
58
2.10
1.50
1.1
1.3
17893.83
32627.57
e6/l
—
6
30
46
329
1.45
1.50
4.6
3.1
4.31
4.41
kpa
0.16
46
317
47
338
1.44
1.49
14.6
9.4
—
—
—
0
0
7
28
2.53
1.46
1.1
1.1
—
—
—
0
0
112
930
1.29
1.42
4.3
3.7
0.00
0.10
estimate
0.60
46
295
7
29
2.44
1.40
1.1
1.1
—
—
—
0
0
142
1217
1.26
1.39
3.7
3.4
7.46
7.85
mmol/l
0.58
128
1002
57
432
1.37
1.36
2.0
1.7
—
—
—
0
0
310
2927
1.29
1.23
6.4
5.6
6.15
6.10
mmol/l
0.24
287
2627
12
64
1.90
1.19
1.2
1.1
—
—
—
0
0
39
284
1.41
1.18
5.9
3.8
—
—
—
0
0
11
57
1.96
1.18
1.1
1.4
—
—
—
0
0
42
312
1.39
1.14
3.0
2.8
0.38
0.64
e6/l
0.39
42
297
137
1194
1.23
1.12
3.8
3.5
63.24
65.22
mg/l
0.04
106
828
34
244
1.43
1.12
1.6
1.4
—
—
—
0
0
140
1229
1.22
1.06
4.3
4.2
12.97
10.84
mg/mmol
0.20
105
814
15
90
1.69
1.05
4.3
3.9
—
—
—
0
0
7
34
2.08
1.03
4.7
5.5
—
—
—
0
0
40
302
1.36
1.00
1.7
1.5
—
—
—
0
0
10
54
1.87
0.97
1.2
1.4
—
—
—
0
0
40
304
1.35
0.97
1.7
1.7
—
—
—
0
0
14
85
1.67
0.95
6.9
4.6
3.51
2.29
mmol/l
—
9
52
11
63
1.77
0.91
2.5
1.3
—
—
—
0
0
6
30
2.02
0.87
1.2
1.3
—
—
—
0
0
6
30
2.02
0.87
1.3
1.1
—
—
—
0
0
6
30
2.02
0.87
2.5
1.3
17082.83
115944.63
e6/l
—
6
19
26
188
1.41
0.85
5.5
3.3
25.75
24.96
mmol/l
0.25
26
178
19
129
1.50
0.85
1.1
1.1
—
—
—
0
0
10
58
1.74
0.80
1.0
1.3
—
—
—
0
0
6
33
1.83
0.79
1.5
1.1
—
—
—
0
0
28
211
1.35
0.74
3.4
2.8
0.68
0.63
%
0.36
28
211
5
25
2.01
0.73
1.4
1.3
2.94
3.00
g/l
—
5
19
5
25
2.01
0.73
1.4
1.3
4.72
8.12
g/l
—
5
19
5
25
2.01
0.73
1.4
1.3
0.18
0.45
g/l
—
5
18
5
25
2.01
0.73
1.2
1.3
—
—
—
0
0
12
76
1.60
0.72
1.2
1.5
256.75
268.92
mu/l
0.11
12
69
7
40
1.76
0.71
2.7
3.3
—
—
—
0
0
46
375
1.26
0.71
1.7
1.6
—
—
—
0
0
5
27
1.86
0.68
2.2
3.1
0.80
0.85
index
—
5
27
22
162
1.38
0.68
2.4
2.0
—
—
—
0
0
28
216
1.32
0.65
3.4
2.9
1.36
1.15
%
0.37
28
216
10
63
1.60
0.62
1.7
2.5
—
—
—
0
0
8
50
1.61
0.61
2.4
1.8
87.17
88.59
%
—
8
50
0
21
0.00
0.60
0.0
1.0
—
1.92
—
0
10
23
175
1.33
0.59
1.3
1.2
—
—
—
0
0
10
65
1.55
0.56
1.2
1.6
—
—
—
0
0
6
37
1.63
0.56
1.7
1.2
—
—
—
0
0
14
99
1.43
0.55
1.2
1.1
—
3.56
—
0
5
6
39
1.55
0.53
1.0
1.1
—
—
—
0
0
6
40
1.51
0.52
1.2
1.1
—
—
—
0
0
32
261
1.25
0.51
5.2
3.1
124.53
127.20
g/l
0.33
32
251
13
92
1.43
0.51
1.7
1.3
—
—
—
0
0
10
67
1.51
0.50
2.8
2.6
54.16
60.70
%
—
10
67
87
964
0.87
0.49
3.3
3.5
—
—
—
0
0
7
45
1.57
0.49
2.1
2.9
—
—
—
0
0
7
50
1.41
0.45
3.3
2.4
4.66
4.80
e9/l
—
7
50
286
2772
1.12
0.42
4.7
4.5
1.29
1.24
mmol/l
0.68
263
2482
10
70
1.44
0.42
2.4
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
154.33
—
0
17
295
2869
1.12
0.39
7.9
7.2
40.42
40.33
mmol/mol
0.07
278
2647
5
35
1.43
0.39
2.6
2.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
80.21
—
0
19
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
9
68
1.33
0.38
1.0
1.1
—
—
—
0
0
305
2975
1.12
0.37
6.3
6.2
2.38
2.49
mmol/l
1.43
285
2689
5
77
0.64
0.36
1.0
1.1
—
—
—
0
0
6
42
1.44
0.35
1.2
1.1
—
—
—
0
0
6
43
1.40
0.35
1.8
3.0
837.33
850.88
mg
—
6
43
6
45
1.34
0.34
1.0
1.1
—
—
—
0
0
19
155
1.24
0.33
1.2
1.2
32.30
130.06
u/ml
—
6
58
32
278
1.16
0.30
3.4
2.9
6.03
6.07
ph
0.09
19
201
7
54
1.30
0.30
2.1
2.9
1.20
1.19
mmol/l
—
7
54
7
55
1.28
0.30
2.1
2.9
107.00
105.76
mmol/l
—
7
55
7
55
1.28
0.30
2.1
2.9
4.06
4.13
mmol/l
—
7
55
12
94
1.29
0.28
17.5
11.4
—
—
—
0
0
14
169
0.82
0.24
1.6
1.4
—
—
—
0
0
296
2906
1.08
0.23
5.6
5.4
4.25
4.34
mmol/l
0.79
278
2645
7
95
0.73
0.22
1.0
1.1
—
—
—
0
0
294
2888
1.07
0.22
5.4
5.3
1.42
1.40
mmol/l
0.27
274
2605
0
10
0.00
0.21
0.0
1.5
—
0.00
—
0
10
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
17
146
1.17
0.19
1.1
1.3
—
—
—
0
0
117
1218
0.94
0.18
2.1
2.0
1.33
1.26
mmol/l
0.38
93
974
23
204
1.14
0.18
1.5
1.4
—
—
—
0
0
7
58
1.21
0.18
1.1
1.3
—
—
—
0
0
7
63
1.11
0.17
7.7
3.4
11.56
9.48
pmol/l
—
7
63
10
84
1.20
0.14
1.9
1.7
50.50
44.43
nmol/l
—
10
76
6
55
1.09
0.09
2.2
2.1
12.17
10.05
mmol/l
—
6
55
6
55
1.09
0.09
1.0
1.4
—
—
—
0
0
9
102
0.88
0.06
7.6
5.1
—
—
—
0
0
17
172
0.99
0.00
2.0
1.6
—
—
—
0
0
12
123
0.97
0.00
2.1
2.0
3.51
3.39
mmol/l
—
7
91
12
116
1.04
0.00
1.8
1.4
0.27
0.32
mg/l
—
5
46
0
6
0.00
0.00
0.0
3.0
—
18.37
—
0
6
0
6
0.00
0.00
0.0
2.7
—
27.39
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
57.33
—
0
9
0
7
0.00
-0.00
0.0
6.4
—
7.50
—
0
7
0
8
0.00
-0.00
0.0
2.0
—
1.17
—
0
8
0
8
0.00
-0.00
0.0
8.6
—
1136.75
—
0
8
5
51
0.98
-0.00
1.4
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: COLITRAD – Colitis due to radiation

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).