No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
474 |
4. Check minimum number of eventsNone |
474 |
5. Include endpointsNone |
474 |
6. Filter based on genotype QC (FinnGen only) |
437 |
Control definitions (FinnGen only)
- Control exclude
- K11_APPENDIX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K35-K38
- Name in latin
- Alii morbi appendicis
Other diseases of appendix
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3360 | 2099 | 1235 |
| Only index persons | 2823 | 1812 | 1011 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.03 |
| Only index persons | 0.06 | 0.07 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 37.74 | 37.44 | 37.89 |
| Only index persons | 33.98 | 34.08 | 33.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 437 | 297 | 140 |
| Unadjusted period prevalence (%) | 0.09 | 0.11 | 0.06 |
| Median age at first event (years) | 38.75 | 37.38 | 41.65 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 447
- Matched controls
- 4470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K38.9
ICD-10 Finland
Disease of appendix, unspecified
1105.3
94.5
89
*
JEA01
NOMESCO Finland
Laparoscopic appendectomy
128.3
87.8
92
9
54301
ICD-8 Finland
Other diseases of appendix, Stercolithium appendicis
+∞
81.8
76
*
K38.8
ICD-10 Finland
Other specified diseases of appendix
+∞
71.8
67
*
54309
ICD-8 Finland
Other diseases of appendix, Unspecified
+∞
58.7
55
*
5439X
ICD-9 Finland
Other diseases of appendix, Other and unspecified diseases of appendix
+∞
45.6
43
*
54308
ICD-8 Finland
Other diseases of appendix, Alii definiti
+∞
44.5
42
*
6421
FHL
Appendicectomy
11.5
42.7
46
44
JEA00
NOMESCO Finland
Appendectomy
10.0
30.4
36
39
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
323.2
30.2
30
*
K38.1
ICD-10 Finland
Appendicular concretions
+∞
28.4
27
*
54300
ICD-8 Finland
Other diseases of appendix, Mucocele appendicis
+∞
18.9
18
*
D37.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Appendix
93.6
16.7
18
*
K38.0
ICD-10 Finland
Hyperplasia of appendix
+∞
15.7
15
*
K35.1
ICD-10 Finland
Acute appendicitis with peritoneal abscess
+∞
15.7
15
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
14.2
84
346
K37
ICD-10 Finland
Unspecified appendicitis
+∞
13.6
13
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.3
12.6
123
638
8480/1-C18.1
ICD-O-3
Low grade appendiceal mucinous neoplasm of appendix
+∞
12.6
12
*
54003
ICD-8 Finland
Acute appendicitis, Cum abscessu
+∞
12.6
12
*
UJF32
NOMESCO Finland
Coloscopy
2.2
12.5
141
775
D12.1
ICD-10 Finland
Benign neoplasm: Appendix
31.0
11.7
15
5
C18.11
ICD-10 Finland
Malignant tumor of the appendix invasive carcinoma
112.6
10.5
11
*
JAH01
NOMESCO Finland
Laparoscopy
3.6
9.9
33
96
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
9.6
175
1127
C18.19
ICD-10 Finland
Malignant tumor in appendix other or unspecified histology
102.1
9.4
10
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
8.9
211
1466
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
8.6
54
227
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
4.6
8.4
20
45
K36
ICD-10 Finland
Other appendicitis
+∞
8.4
8
*
54399, ,
ICD-8 Finland
+∞
7.3
7
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
6.8
136
883
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
6.4
56
273
54099
ICD-8 Finland
Acute appendicitis, Without mention of peritonitis
+∞
6.3
6
*
8480/3-C18.1
ICD-O-3
Mucinous adenocarcinoma of appendix
+∞
6.3
6
*
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.2
6.3
24
77
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
95
434
2.51
12.96
4.3
4.4
3.15
18.77
ug/l
0.91
76
350
23
42
5.72
12.24
3.3
3.5
2.37
3.39
nmol/l
0.97
23
42
17
23
7.64
7.74
3.1
4.3
59.41
143.91
nmol/l
0.69
17
23
185
1289
1.74
7.34
3.3
2.6
54.14
65.60
u/l
1.36
169
1203
275
2171
1.69
6.64
9.3
6.7
11.13
11.24
umol/l
0.05
261
2072
39
169
2.43
5.86
4.1
2.9
1154.77
1407.09
u/ml
0.08
31
144
236
1836
1.60
5.66
3.5
2.7
—
—
estimate
—
0
0
56
289
2.07
5.56
1.4
1.6
—
—
—
0
0
136
960
1.60
4.72
3.2
2.3
—
—
—
0
0
228
1808
1.53
4.71
6.3
4.8
36.27
35.91
g/l
0.47
211
1698
46
244
1.99
4.25
2.4
2.6
25.41
65.39
u/ml
1.22
46
235
301
2573
1.52
4.10
5.7
4.8
1686.14
2893.10
e6/l
—
7
42
347
3074
1.58
3.89
11.1
8.5
79.41
78.98
u/l
0.06
330
2914
197
1559
1.47
3.87
4.0
3.9
30.42
69.35
ng/l
0.52
139
1114
273
2342
1.43
3.26
7.7
4.7
6.74
6.64
mmol/l
0.30
268
2230
334
2987
1.47
3.09
4.7
4.5
11.78
12.19
mm/h
0.24
311
2789
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
100
2.26
3.04
2.8
2.7
0.50
0.38
iu/ml
—
9
59
265
2283
1.39
2.96
10.1
9.8
4.22
4.03
e9/l
0.59
238
1991
221
1851
1.38
2.91
9.2
6.0
1.21
1.22
mmol/l
0.19
203
1712
221
1868
1.36
2.67
17.2
12.9
1.22
1.21
inr
0.08
183
1536
70
481
1.54
2.64
6.0
2.8
7.84
7.45
umol/l
0.06
65
428
238
2041
1.36
2.59
10.3
6.9
1.21
1.21
mmol/l
0.01
206
1765
60
400
1.58
2.59
2.4
2.0
390.25
373.06
nmol/l
0.24
55
378
58
393
1.55
2.34
4.1
2.6
66.22
46.45
u/l
0.27
49
319
15
66
2.32
2.27
1.4
1.5
—
—
—
0
0
5
9
5.60
2.22
1.4
1.6
—
—
—
0
0
121
956
1.36
2.17
1.2
1.3
2.19
1.76
u/ml
0.11
29
262
51
345
1.54
2.09
1.8
2.5
65.96
67.43
g/l
0.53
45
324
13
56
2.36
2.06
1.2
1.4
—
—
—
0
0
13
56
2.36
2.06
1.2
1.4
—
—
—
0
0
13
57
2.32
1.99
1.2
1.4
—
—
—
0
0
13
57
2.32
1.99
1.2
1.4
—
—
—
0
0
10
39
2.60
1.95
1.2
1.2
—
—
—
0
0
13
58
2.28
1.92
1.2
1.4
—
—
—
0
0
13
58
2.28
1.92
1.2
1.4
—
—
—
0
0
37
237
1.61
1.91
1.8
1.8
—
—
—
0
0
14
65
2.19
1.90
1.8
1.5
—
—
—
0
0
81
615
1.39
1.85
3.6
3.0
4.94
2.91
e6/l
0.47
39
284
297
2700
1.30
1.84
4.8
3.4
52.12
47.62
u/l
0.29
284
2548
14
66
2.16
1.84
1.1
1.4
—
—
—
0
0
125
1017
1.32
1.82
6.7
3.8
93.24
92.32
%
0.15
125
1000
7
24
2.95
1.73
7.4
1.7
116.71
107.58
%
—
7
24
88
685
1.35
1.72
2.1
2.0
—
—
—
0
0
66
491
1.40
1.70
5.8
4.9
33.98
32.28
%
0.59
52
316
86
669
1.35
1.69
3.6
2.9
1.14
0.97
e6/l
0.20
44
338
241
2154
1.26
1.62
4.3
4.1
0.00
0.72
estimate
0.51
48
425
240
2145
1.26
1.61
4.3
4.1
0.00
7.48
estimate
0.80
47
468
24
144
1.70
1.61
2.2
2.1
—
—
—
0
0
14
70
2.03
1.61
1.5
1.3
—
200.00
—
0
7
5
15
3.36
1.52
1.0
1.0
—
—
—
0
0
394
3761
1.40
1.51
19.0
15.3
82.00
80.57
ml/min/173m2
0.78
375
3494
23
139
1.69
1.51
2.1
1.8
—
—
—
0
0
32
211
1.56
1.50
1.4
1.4
—
—
—
0
0
237
2126
1.24
1.50
4.3
4.0
0.00
0.00
estimate
0.50
46
452
15
80
1.91
1.46
1.4
1.5
—
—
—
0
0
169
1468
1.24
1.42
4.1
3.4
2.36
2.36
mmol/l
0.14
146
1332
132
1116
1.26
1.40
3.7
3.1
0.25
0.50
e6/l
1.96
98
811
84
671
1.31
1.39
1.7
1.5
—
—
—
0
0
6
23
2.63
1.37
1.8
1.3
—
—
—
0
0
67
520
1.34
1.35
1.7
1.9
—
—
—
0
0
18
105
1.74
1.35
1.1
1.2
—
—
—
0
0
44
319
1.42
1.33
5.2
3.7
80.31
82.76
ng/l
0.08
38
286
8
34
2.38
1.29
2.0
1.3
—
—
—
0
0
209
1875
1.22
1.25
3.0
2.5
78.04
78.31
nmol/l
0.05
191
1685
124
1057
1.24
1.21
2.7
2.8
323.40
336.94
umol/l
0.90
115
941
5
20
2.52
1.15
2.0
1.3
—
—
—
0
0
139
1209
1.22
1.12
4.2
4.1
0.00
0.01
estimate
0.88
45
436
57
446
1.32
1.11
15.1
7.4
0.79
1.09
mmol/l
0.28
47
374
7
31
2.28
1.11
1.0
1.2
—
—
—
0
0
14
81
1.75
1.10
1.6
1.9
—
—
—
0
0
57
448
1.31
1.08
15.1
7.4
13.50
12.17
kpa
1.02
51
436
57
448
1.31
1.08
15.2
7.4
5.15
5.12
kpa
0.10
51
433
16
97
1.67
1.08
1.4
1.5
—
—
—
0
0
329
3109
1.22
1.07
4.7
4.5
14.78
14.77
pmol/l
0.02
301
2853
19
121
1.60
1.07
1.2
1.3
—
—
—
0
0
14
82
1.73
1.06
1.4
1.5
—
—
—
0
0
7
33
2.14
1.06
1.3
1.2
132.43
108.30
pmol/l
—
7
33
21
138
1.55
1.05
1.6
1.6
—
—
—
0
0
17
106
1.63
1.04
3.0
3.3
4.00
2.18
index
—
10
60
379
3640
1.27
1.04
5.7
5.5
1.86
1.91
mu/l
0.38
349
3367
5
22
2.29
1.03
2.0
1.3
—
—
—
0
0
19
123
1.57
1.01
1.5
1.8
—
—
—
0
0
9
48
1.89
1.01
1.1
1.3
63.42
44.64
u/l
—
9
43
179
1614
1.18
0.96
4.2
4.0
0.02
0.02
estimate
0.07
41
361
157
1401
1.19
0.95
4.4
3.2
33.72
32.32
u/l
0.20
148
1336
11
62
1.79
0.95
1.8
1.5
—
—
—
0
0
92
782
1.22
0.93
4.8
4.1
203.98
320.86
ng/l
0.38
64
611
14
86
1.65
0.92
1.1
1.1
65.38
11.13
e6/l
—
8
61
25
179
1.42
0.86
1.4
1.8
14.96
6.64
iu/ml
—
8
37
134
1190
1.18
0.85
1.9
1.7
20.18
21.15
nmol/l
0.31
113
1009
18
121
1.51
0.84
1.6
1.7
—
—
—
0
0
23
163
1.43
0.84
1.3
1.7
2.30
3.33
ug/l
0.21
18
144
12
73
1.66
0.82
4.3
3.8
33.83
35.95
umol/l
0.17
12
60
55
450
1.25
0.79
6.5
7.0
—
—
—
0
0
19
131
1.47
0.79
1.2
1.3
—
—
—
0
0
206
1902
1.15
0.78
3.2
3.0
135.32
118.72
ug/l
0.27
189
1762
80
683
1.21
0.78
1.7
1.7
1212.98
1190.25
nmol/l
0.09
58
505
396
3851
1.25
0.76
20.6
15.8
23.86
22.56
mg/l
0.29
346
3171
23
167
1.40
0.75
2.6
1.6
0.27
0.35
mg/l
0.30
12
74
5
24
2.10
0.74
1.0
2.7
52.40
127.77
ng/l
—
5
24
7
38
1.86
0.74
1.1
1.8
—
—
—
0
0
5
26
1.93
0.71
4.4
2.0
—
—
—
0
0
196
1814
1.14
0.70
2.3
2.1
104.52
97.31
pmol/l
0.90
104
910
7
41
1.72
0.70
1.0
1.0
—
—
—
0
0
59
495
1.22
0.70
1.8
1.9
—
—
—
0
0
19
136
1.41
0.68
1.3
1.3
—
—
—
0
0
13
86
1.53
0.66
2.3
1.9
770.22
3984.68
u/l
—
5
28
12
78
1.55
0.66
2.6
3.9
31.57
27.02
mg/l
—
7
52
7
44
1.60
0.65
1.4
1.0
—
—
—
0
0
144
1312
1.14
0.65
2.4
2.2
167.17
187.17
u/l
0.25
138
1251
23
174
1.34
0.61
1.5
1.8
—
—
—
0
0
8
51
1.58
0.60
1.3
2.1
—
—
—
0
0
415
4073
1.26
0.60
15.4
12.5
26.86
25.67
u/l
0.88
407
3971
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
6
35
1.72
0.58
1.3
1.2
—
—
—
0
0
6
35
1.72
0.58
1.3
1.2
—
—
—
0
0
48
404
1.21
0.57
2.0
2.1
3.40
3.48
ratio
0.21
36
333
137
1255
1.13
0.56
2.9
3.2
1239.35
1109.09
ng/l
0.15
119
1058
103
926
1.15
0.56
2.2
1.7
2.02
1.24
mg/l
0.35
80
736
8
55
1.46
0.56
1.0
1.3
0.51
34.61
nmol/l
—
8
50
35
285
1.25
0.56
1.1
1.2
94.58
153.30
u/ml
0.53
12
114
18
133
1.37
0.56
2.7
2.5
—
—
—
0
0
9
60
1.51
0.54
1.9
1.5
—
—
—
0
0
28
223
1.27
0.54
4.5
3.5
2.12
2.08
mmol/l
0.02
22
162
37
306
1.23
0.52
1.5
1.5
—
—
—
0
0
27
215
1.27
0.52
2.7
2.3
0.61
0.61
%
0.03
27
215
19
145
1.32
0.49
1.5
1.8
—
—
—
0
0
127
1169
1.12
0.48
3.6
3.4
0.23
0.08
estimate
0.28
43
366
7
46
1.53
0.48
1.3
2.2
—
—
—
0
0
314
3241
0.90
0.47
24.3
20.3
332.49
331.66
g/l
0.92
314
3225
12
85
1.42
0.47
1.4
1.5
—
—
—
0
0
62
545
1.16
0.47
16.1
6.4
105.26
104.07
mmol/l
1.48
62
545
104
948
1.13
0.47
4.3
4.2
1.02
1.02
kg/l
0.26
70
631
7
49
1.44
0.46
1.0
1.2
0.16
0.18
nmol/l
—
7
32
17
130
1.32
0.44
2.9
1.9
—
—
—
0
0
15
114
1.33
0.41
1.4
1.2
—
—
—
0
0
8
59
1.36
0.41
1.4
1.1
—
—
—
0
0
5
35
1.43
0.39
2.2
1.4
65.86
52.02
ug/l
—
5
35
17
133
1.29
0.39
1.1
1.3
2.14
6.89
u/ml
—
5
19
5
36
1.39
0.38
2.4
1.6
—
—
—
0
0
92
845
1.11
0.37
1.5
1.8
166667141.72
16433030.47
pmol/l
0.68
75
712
35
300
1.18
0.37
1.7
1.9
3.51
3.54
mmol/l
0.03
22
228
92
846
1.11
0.36
1.3
1.3
33.86
34.96
iu/ml
0.03
27
270
43
376
1.16
0.36
6.2
3.5
1.76
2.17
mmol/l
0.46
38
324
9
71
1.27
0.36
1.0
1.3
—
—
—
0
0
9
71
1.27
0.36
1.0
1.3
—
—
—
0
0
6
41
1.47
0.36
1.2
1.8
—
—
—
0
0
6
41
1.47
0.36
1.2
1.8
—
—
—
0
0
6
41
1.47
0.36
1.2
1.8
—
—
—
0
0
5
78
0.64
0.36
1.2
1.2
78.18
17.95
u/l
—
5
66
81
742
1.11
0.35
4.7
4.3
20.51
22.03
%
0.43
45
342
6
44
1.37
0.34
2.0
2.5
—
—
—
0
0
71
647
1.12
0.33
1.4
1.4
—
—
—
0
0
24
201
1.21
0.33
1.7
1.3
—
—
—
0
0
23
192
1.21
0.32
1.0
1.0
—
—
—
0
0
166
1742
0.93
0.32
2.0
2.0
1.37
1.37
mmol/l
0.02
146
1476
422
4179
1.18
0.29
30.2
24.2
253.54
253.76
e9/l
0.02
417
4109
422
4181
1.17
0.27
30.1
24.2
4.41
4.47
e12/l
1.56
417
4098
91
851
1.09
0.27
3.4
2.8
2.44
2.46
mmol/l
0.50
83
757
131
1376
0.93
0.26
3.9
4.2
2.75
8.23
mg/mmol
4.33
78
826
38
340
1.13
0.25
5.5
2.8
4.19
4.44
kpa
0.45
38
329
110
1043
1.07
0.23
2.6
2.1
3.24
3.04
mg/l
0.35
97
891
22
190
1.17
0.23
1.5
1.3
30.02
31.42
iu/l
0.05
17
164
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
36
324
1.12
0.22
2.2
2.4
10.31
6.89
ug/l
0.47
29
291
381
3762
1.09
0.22
5.3
5.3
5.97
5.95
mmol/l
0.10
353
3468
5
40
1.25
0.22
1.0
1.0
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.6
2.5
1.60
0.32
mmol/l
—
5
41
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
27.35
—
0
12
0
12
0.00
0.21
0.0
1.7
—
7.55
—
0
12
6
48
1.25
0.20
1.2
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.20
0.20
2.2
2.5
1.17
1.19
mmol/l
—
6
50
6
51
1.18
0.19
2.2
2.5
106.50
105.12
mmol/l
—
6
51
371
3668
1.07
0.18
4.4
4.4
1.32
1.30
mmol/l
0.16
350
3385
81
771
1.06
0.16
1.3
1.3
5.08
11.63
u/ml
1.22
24
297
61
576
1.07
0.15
3.9
3.1
0.79
0.72
ug/l
0.35
43
354
16
140
1.15
0.15
1.3
1.2
0.84
0.91
g/l
0.72
16
140
13
113
1.15
0.13
1.4
1.3
—
—
—
0
0
13
113
1.15
0.13
1.4
1.3
—
—
—
0
0
14
123
1.14
0.12
2.6
3.6
1.65
2.32
ratio
—
8
71
56
532
1.06
0.12
9.1
5.5
0.99
1.04
mmol/l
1.00
51
494
43
405
1.07
0.12
3.3
3.4
—
—
—
0
0
36
337
1.07
0.12
2.5
2.7
63.77
66.28
ml/min/173m2
0.14
13
152
5
45
1.11
0.10
1.4
1.2
—
—
—
0
0
42
399
1.06
0.09
6.4
3.4
5.62
5.80
kpa
0.77
42
388
10
87
1.15
0.09
3.8
2.6
6.40
7.82
pmol/l
—
10
87
389
3913
0.95
0.09
5.9
6.1
2.76
2.75
mmol/l
0.08
369
3643
11
97
1.14
0.09
1.3
1.7
—
—
—
0
0
6
54
1.11
0.09
1.7
1.6
61.60
54.04
ug/l
—
6
45
12
108
1.11
0.07
1.7
1.5
—
—
—
0
0
10
89
1.13
0.07
1.4
1.4
—
—
—
0
0
373
3713
1.03
0.05
6.4
6.6
39.16
39.26
mmol/mol
0.09
346
3510
66
644
1.03
0.05
3.4
2.4
2.29
2.30
g/l
0.03
61
595
31
322
0.96
0.04
1.6
1.9
—
—
—
0
0
382
3833
0.98
0.03
5.2
5.2
1.51
1.51
mmol/l
0.15
364
3564
141
1424
0.99
0.03
3.1
3.4
7.31
7.37
mmol/l
0.05
116
1200
384
3851
0.98
0.03
5.3
5.3
4.74
4.72
mmol/l
0.14
365
3602
13
124
1.05
0.00
1.3
1.2
—
—
—
0
0
14
134
1.05
0.00
1.1
1.1
1.59
1.58
g/l
0.01
14
134
12
125
0.96
0.00
1.3
1.1
—
—
—
0
0
11
114
0.96
0.00
1.5
1.3
250.33
248.22
miu/ml
—
6
50
12
124
0.97
0.00
1.3
1.1
—
—
—
0
0
13
134
0.97
0.00
1.5
1.4
—
—
—
0
0
36
359
1.00
0.00
1.8
2.0
—
—
—
0
0
241
2406
1.00
0.00
3.0
3.0
—
—
—
0
0
92
925
0.99
0.00
6.3
5.2
3.19
2.46
ug/l
0.53
86
840
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
9
92
0.98
-0.00
2.2
1.6
1037.98
1002.72
mu/l
—
9
78
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
116.29
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
11.2
—
10.95
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
1.17
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
166.75
—
0
8
0
5
0.00
-0.00
0.0
5.0
—
59.90
—
0
5
0
5
0.00
-0.00
0.0
6.0
—
4.82
—
0
5
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
90.71
—
0
7
0
5
0.00
-0.00
0.0
1.8
—
6.18
—
0
5
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_OTHAPPEND and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_OTHAPPEND | 1.183 [0.87, 1.6] | 0.277 |
| Birth year | 0.996 [0.99, 1.0] | 0.385 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 525 females with K11_OTHAPPEND died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_OTHAPPEND | 1.303 [0.91, 1.86] | 0.142 |
| Birth year | 0.989 [0.98, 1.0] | 0.026 |
During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 371 males with K11_OTHAPPEND died.
Mortality risk
Mortality risk for people of age
years, who have K11_OTHAPPEND.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.09% | 0.251% |
| 5 | 0.711% | 1.634% |
| 10 | 1.591% | 4.017% |
| 15 | 3.205% | 7.607% |
| 20 | 6.275% | 13.089% |
Relationships between endpoints
↥Index endpoint: K11_OTHAPPEND – Other diseases of appendix
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data