Adult respiratory distress syndrome

J10_ARDS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519870

1. Apply sex-specific rule

None

519870

2. Check conditions

None

519870

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J80
  • Hospital discharge: ICD-9 5185
  • Cause of death: ICD-10 J80
  • Cause of death: ICD-9 5185

2 out of 7 registries used, show all original rules.

496

4. Check minimum number of events

None

496

5. Include endpoints

None

496

6. Filter based on genotype QC (FinnGen only)

471

Control definitions (FinnGen only)

Control exclude
J10_INTERSTITIUM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
J80-J84
Name in latin
Syndroma dyspnoicum adultorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4454 1675 2699
Only index persons 2675 1057 1618
Unadjusted period prevalence (%)
Whole population 0.07 0.05 0.08
Only index persons 0.05 0.04 0.06
Median age at first event (years)
Whole population 64.11 63.05 64.59
Only index persons 63.57 61.33 65.04

-FinnGen-

Key figures

All Female Male
Number of individuals 471 171 300
Unadjusted period prevalence (%) 0.11 0.06 0.14
Median age at first event (years) 63.42 55.98 67.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
496
Matched controls
4960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J80
ICD-10 Finland
Adult respiratory distress syndrome
+∞
307.7
474
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
6.2
89.3
313
1077
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.0
83.4
219
580
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.8
65.6
121
225
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.8
60.9
137
307
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
9.1
58.7
78
100
WX730
NOMESCO Finland
Conventional respirator
19.0
52.1
42
24
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
515.0
48.2
47
*
WX872
NOMESCO Finland
Intensive care
6.8
48.2
83
142
GD1AD
NOMESCO Finland
Thorax CT examination
5.7
38.3
79
160
GBB00
NOMESCO Finland
Tracheostomy
15.1
37.7
34
24
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
+∞
34.8
33
*
J96.0
ICD-10 Finland
Acute respiratory failure
12.5
33.7
34
29
TK800
NOMESCO Finland
Hemodialysis
9.2
32.7
41
48
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.6
31.2
82
203
TGC00
NOMESCO Finland
Bronchial lavation
7.6
28.0
41
58
WX892
NOMESCO Finland
Monitored bed care
4.3
26.6
77
205
L04AA06
ATC
mycophenolic acid; systemic
10.2
25.2
29
30
ZXD05
NOMESCO Finland
Urgent procedure
2.7
24.9
207
1038
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.5
24.6
65
161
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
7.3
24.5
37
54
A41.9
ICD-10 Finland
Sepsis, unspecified
5.4
24.3
50
100
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.7
24.2
61
145
5185A
ICD-9 Finland
Other diseases of lung, Pulmonary insufficiency following trauma and surgery
+∞
23.1
22
*
J01MA12
ATC
levofloxacin; systemic
2.7
21.2
144
644
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
+∞
19.9
19
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.8
19.1
36
66
WX882
NOMESCO Finland
High dependency care
6.0
18.3
33
58
H02AB06
ATC
prednisolone; systemic
2.3
18.1
279
1780
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
17.9
92
352
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
17.7
145
704
C03CA01
ATC
furosemide; systemic
2.3
17.5
226
1336
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
17.5
97
387
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
17.0
98
398
WX725
NOMESCO Finland
Noninvasive ventilation
4.0
16.9
50
134
J81
ICD-10 Finland
Pulmonary oedema
+∞
16.8
16
*
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.1
15.9
28
48
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
15.7
15.0
24
16
JN4BD
NOMESCO Finland
Extensive body CT
2.8
14.8
81
319
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.8
14.7
83
332
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.8
14.6
23
35
A98
ICPC
Health maint/preventive medicine
0.5
14.5
334
4071
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
13.9
276
1874
R50.9
ICD-10 Finland
Fever, unspecified
2.5
13.7
100
455
J01MA14
ATC
moxifloxacin; systemic
2.9
13.6
71
272
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
13.4
76
305
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
13.0
84
359
127
Kela drug reimbursment
Transplant complication
11.4
12.6
23
21
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
17.9
12.6
19
11
J96.1
ICD-10 Finland
Chronic respiratory failure
4.8
12.3
28
61
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.7
12.2
40
115
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
21.9
12.1
17
8
WX722
NOMESCO Finland
PEEP
3.3
11.8
47
154
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.5
11.6
42
129
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
11.4
61
236
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
11.4
117
612
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.9
11.3
25
53
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.7
11.3
21
38
XG410
NOMESCO Finland
Flow-volume spirometry
3.9
11.2
33
88
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.9
10.6
32
87
N05AA02
ATC
levomepromazine; systemic
3.7
10.4
34
98
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
4.6
10.1
24
54
A10AC01
ATC
insulin (human); parenteral
2.7
10.0
58
234
WX704
NOMESCO Finland
Intubation
2.9
10.0
50
187
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
9.9
36
111
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.3
9.8
38
122
L04AX01
ATC
azathioprine; systemic
4.2
9.8
26
64
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.1
9.7
27
69
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.5
9.6
63
270
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
9.6
137
805
Z2446
NOMESCO Finland
Social worker
2.9
9.5
45
163
B01AA03
ATC
warfarin; systemic
2.0
9.5
131
762
WX726
NOMESCO Finland
High-flow oxygen therapy
+∞
9.4
9
*
N03AX16
ATC
[U] pregabalin
2.0
9.3
125
718
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.8
9.3
28
76
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
9.2
33
101
A01AB10
ATC
natamycin; local oral
4.6
9.2
22
50
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
9.1
128
747
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
8.9
95
502
Z3226
NOMESCO Finland
Physiotherapist
2.1
8.9
102
554
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
8.6
91
479
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
8.5
157
998
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.4
8.5
30
91
TQW11
NOMESCO Finland
Vacuum treatment of wound
4.6
8.4
20
45
R06.0
ICD-10 Finland
Dyspnoea
1.8
8.4
154
977
ZX120
NOMESCO Finland
Intravenous
2.4
8.4
62
281
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
7.7
8.2
18
24
A10AB05
ATC
insulin aspart; parenteral
2.6
8.2
49
201
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
17.5
8.1
12
7
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
8.0
136
841
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.3
7.8
20
48
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
7.8
29
91
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
3.5
7.6
26
77
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.9
7.6
22
58
J15.8
ICD-10 Finland
Other bacterial pneumonia
9.6
7.3
14
15
284
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
7.3
7
*
R03BB04
ATC
tiotropium bromide; inhalant
2.1
7.2
72
369
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.0
7.2
20
51
XG466
NOMESCO Finland
Sleep oxymetry
3.5
7.2
25
75
L04AD01
ATC
ciclosporin; systemic
6.7
7.2
17
26
RS220, ,
NOMESCO Finland
10.2
7.1
13
13
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.3
7.1
18
43
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.5
7.1
47
203
K85
ICD-10 Finland
Acute pancreatitis
4.5
7.0
17
39
K65.0
ICD-10 Finland
Acute peritonitis
7.7
6.9
15
20
J12.8
ICD-10 Finland
Other viral pneumonia
8.4
6.9
14
17
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
6.8
78
422
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.0
6.7
29
100
GX2D5
NOMESCO Finland
Sleep oximetry
22.9
6.7
9
*
H02AB04
ATC
methylprednisolone; systemic
2.0
6.7
81
446
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
5.6
6.7
18
33
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.5
6.7
42
177
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.4
6.6
23
69
J93.8
ICD-10 Finland
Other pneumothorax
10.2
6.6
12
12
Z94.0
ICD-10 Finland
Kidney transplant status
10.2
6.6
12
12
N17.8
ICD-10 Finland
Other acute renal failure
7.0
6.6
15
22
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.0
6.5
28
96
Z49.1
ICD-10 Finland
Extracorporeal dialysis
6.3
6.5
16
26
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.5
6.4
14
19
137
Kela drug reimbursment
Uraemia requiring dialysis
9.4
6.3
12
13
JN4AD
NOMESCO Finland
Body CT examination
2.0
6.3
68
359
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
6.3
25
82
356
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
6.3
6
*
P01BA02
ATC
hydroxychloroquine; oral
2.4
6.2
41
177
C07AB07
ATC
bisoprolol; oral
1.6
6.2
262
2042
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.4
6.1
41
178
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
6.1
36
147
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
8.8
6.1
12
14
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.8
6.1
14
21
ZXD00
NOMESCO Finland
Emergency procedure
3.4
6.1
21
63
J12.9
ICD-10 Finland
Viral pneumonia, unspecified
10.2
6.1
11
11

TimeCodeWAS

TODO / Current known limitations:

  • Only showing the top 500 codes, because showing all (sometimes 20k) makes the page too slow.
  • Legend / how to read the glyphs.
  • Proper column names.
  • Show details (e.g. Fisher or Chi-square test, N cases and N controls) when clicking on a row.
  • Explanation on the underlying data / how the TimeCodeWAS is done (e.g. matched cases / controls, eligibility).
  • Download CSV not working.
  • No filters and sorters.
  • Limited amount of endpoints with TimeCodeWAS data.
  • Cross-links to Risteys lab test pages for lab test codes.
OMOP Concept
ln(OR) -5y
ln(OR) -1y
ln(OR) -1m
ln(OR) d0
ln(OR) +1m
ln(OR) +1y
ln(OR) +5y
MCC -5y
MCC -1y
MCC -1m
MCC d0
MCC +1m
MCC +1y
MCC +5y
Other interstitial pulmonary diseases with fibrosis
J84.1 (45557630)
Interstitial pulmonary disease, unspecified
J84.9 (45543277)
Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
29257-3 (3002482)
Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
23826-1 (3012477)
Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
21363-7 (3020565)
Adult respiratory distress syndrome
J80 (45552897)
Ultrasound examination of lower leg veins
PH2AE (2001309451)
PEEP
WX722 (2001310825)
Conventional respirator
WX730 (2001310831)
Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
40976-3 (3040853)
Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
38917-1 (3042194)
Human coronavirus RNA [Presence] in Specimen by NAA with probe detection
41001-9 (3042596)
Human bocavirus DNA [Presence] in Specimen by NAA with probe detection
62424-7 (40765161)
Parainfluenza type 1 nucleic acid detection
222341000000100 (44790047)
Parainfluenza type 2 nucleic acid detection
222351000000102 (44790048)
Parainfluenza type 3 nucleic acid detection
222361000000104 (44790049)
Parainfluenza type 4 nucleic acid detection
810871000000102 (44806118)
Pneumonia due to Streptococcus pneumoniae
J13 (45586662)
Acute respiratory failure
J96.0 (45605905)
Gas panel - Central venous blood
97535-9 (1616796)
Extensive CT examination of arteria pulmonalis
FB1BD (2001302407)
Tracheostomy
GBB00 (2001303560)
Thorax CT examination
GD1AD (2001303618)
High resolution CT examination of lungs
GD1DD (2001303632)
Insertion of central venous catheter through external or internal jugular vein
TPH15 (2001309600)
Noninvasive ventilation
WX725 (2001310828)
Intensive care
WX872 (2001310844)
SMOKING - SMOKE2: no - SMOKE3: never - SMOKE5: Unspecified
SMOKING-2-3-0 (2002330113)
Gas panel - Venous blood
24339-4 (3000991)
Vancomycin [Mass/volume] in Serum or Plasma
20578-1 (3005715)
Methemoglobin/Hemoglobin.total in Arterial blood
2615-3 (3006217)
Bicarbonate [Moles/volume] in Arterial blood
1960-4 (3008152)
Pneumocystis jirovecii DNA [Presence] in Specimen by NAA with probe detection
6521-9 (3009595)
Fractional oxyhemoglobin in Arterial blood
2714-4 (3014007)
Lactate [Moles/volume] in Serum or Plasma
2524-7 (3014111)
Bicarbonate [Moles/volume] standard in Arterial blood
19230-2 (3014218)
Enterovirus RNA [Presence] in Specimen by NAA with probe detection
29591-5 (3016881)
Chloride [Moles/volume] in Blood
2069-3 (3018572)
Gas panel - Arterial blood
24336-0 (3019060)
Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
3216-9 (3020427)
Myeloperoxidase Ab [Units/volume] in Serum
6969-0 (3023150)
Bacteria identified in Sputum by Culture
6460-0 (3023419)
Rhinovirus RNA [Presence] in Specimen by NAA with probe detection
7993-9 (3025023)
Carboxyhemoglobin/Hemoglobin.total in Arterial blood
2030-5 (3028653)
Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection
50548-7 (3030692)
Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
34645-2 (3031478)
Glomerular basement membrane Ab [Units/volume] in Serum
49774-3 (3032700)
Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
41009-2 (3038546)
Anion gap in Blood by calculation
41276-7 (3039000)
Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
41005-0 (3040359)
Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
41003-5 (3041642)
Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
40988-8 (3044254)
Procalcitonin [Mass/volume] in Serum or Plasma
33959-8 (3046279)
Lactate [Moles/volume] in Blood
32693-4 (3047181)
Oxygen capacity [Volume Fraction] in Arterial blood
59275-8 (40762366)
Body height measure
50373000 (4177340)
Body mass index
60621009 (4245997)
Pneumonitis due to food and vomit
J69.0 (45591562)
Influenza with pneumonia, seasonal influenza virus identified
J10.0 (45601119)
Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
76080-1 (46235759)
Other diseases of lung, Pulmonary insufficiency following trauma and surgery
5185A (2000404064)
Standard cardiac ultrasound examination
FM1AE (2001303278)
Extensive structural and functional ultrasound examination of heart
FM1EE (2001303307)
ECG with 12 standard connections
XF400 (2001303368)
Flexible bronchoscopy
UGC12 (2001303610)
Thorax extensive CT-examination
GD1BD (2001303621)
X-ray examination of the lungs in one projection
GD1PA (2001303645)
Supine thorax X-ray examination
GD1QA (2001303648)
Thorax X-ray examination outside radiological department
GD1UA (2001303652)
Ultrasound examination of upper part of abdomen
JN1AE (2001305517)
Cathetrisation of vein
TPH04 (2001309597)
Cathetrisation of artery
TPH07 (2001309747)
Physiotherapy
R4110 (2001310233)
High dependency care
WX882 (2001310847)
Monitored bed care
WX892 (2001310850)
Body CT examination
JN4AD (2001310897)
Extensive body CT
JN4BD (2001310899)
Urgent procedure
ZXD05 (2001311386)
One hour or less
ZXE00 (2001311394)
More than one and less than three hours
ZXE10 (2001311401)
Medical doctor
Z2221 (2001311556)
Physiotherapist
Z3226 (2001311560)
bisoprolol; oral
C07AB07 (21601689)
Fungus identified in Specimen by Culture
580-1 (3000494)
Complement C3 [Mass/volume] in Serum or Plasma
4485-9 (3000620)
Epithelial cells [#/volume] in Urine
30383-4 (3000850)
Neutrophil cytoplasmic Ab [Units/volume] in Serum
5128-4 (3001334)
Hemoglobin [Mass/volume] in Arterial blood
30313-1 (3002173)
Erythrocytes [#/volume] in Urine
30391-7 (3002582)
Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
14278-6 (3003284)
Base excess in Arterial blood by calculation
1925-7 (3003396)
Phosphate [Moles/volume] in Serum or Plasma
14879-1 (3003458)
Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
14277-8 (3004383)
Creatine kinase [Enzymatic activity/volume] in Serum or Plasma
2157-6 (3007220)
Methemoglobin/Hemoglobin.total in Blood
2614-6 (3007930)
Proteinase 3 Ab [Units/volume] in Serum
6968-2 (3009445)
Natriuretic peptide B [Mass/volume] in Serum or Plasma
30934-4 (3011960)
Magnesium [Moles/volume] in Serum or Plasma
2601-3 (3012095)
pH of Venous blood
2746-6 (3012544)
EKG study
11524-6 (3013512)
Prealbumin [Mass/volume] in Serum or Plasma
14338-8 (3013742)
Bicarbonate [Moles/volume] in Serum or Plasma
1963-8 (3016293)
Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
19072-8 (3016431)
Oxygen saturation in Arterial blood
2708-6 (3016502)
Complement C4 [Mass/volume] in Serum or Plasma
4498-2 (3017766)
Leukocytes [#/volume] in Urine
30405-5 (3018095)
pH of Arterial blood
2744-1 (3019977)
Urea [Moles/volume] in Serum or Plasma
22664-7 (3020779)
Troponin I.cardiac [Mass/volume] in Serum or Plasma
10839-9 (3021337)
Calcium.ionized [Moles/volume] in Serum or Plasma
1995-0 (3021347)
Carboxyhemoglobin/Hemoglobin.total in Blood
20563-3 (3023081)
Ammonium ion [Moles/volume] in Plasma
1845-7 (3023183)
Bacteria identified in Blood by Culture
600-7 (3023368)
Bacteria identified in Urine by Culture
630-4 (3026008)
Oxygen [Partial pressure] in Arterial blood
2703-7 (3027801)
Carbon dioxide [Partial pressure] in Arterial blood
2019-8 (3027946)
Urinalysis microscopic panel [#/volume] - Urine by Automated count
50554-5 (3029287)
Casts [#/volume] in Urine by Automated count
51483-6 (3030467)
Prothrombin time (PT) actual/Normal
5894-1 (3033658)
Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
40982-1 (3038288)
Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
40987-0 (3043924)
Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
34487-9 (3044938)
Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
48065-7 (3051714)
Bacteria [Presence] in Urine
87829-8 (36304419)
General Practice
1 (38004446)
Cardiology
6 (38004451)
Psychiatry
26 (38004469)
Infectious Disease
44 (38004484)
CBC W Ordered Manual Differential panel - Blood
57782-5 (40760892)
Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
61365-3 (40764126)
Pulmonary embolism without mention of acute cor pulmonale
I26.9 (45552785)
Bacterial pneumonia, unspecified
J15.9 (45557621)
Dyspnoea
R06.0 (45558449)
Sleep apnoea
G47.3 (45562094)
Asthma, unspecified
J45.9 (45562456)
Acute renal failure, unspecified
N17.9 (45567829)
Heart failure, unspecified
I50.9 (45576879)
Sepsis, unspecified
A41.9 (45585911)
Atherosclerotic heart disease
I25.1 (45596196)
Pneumonia, unspecified
J18.9 (45601123)
Emergency use of U07.1 | COVID-19, virus identified
U07.1 (45756093)
Thoracic and Cardiac Surgery
OMOP4822009 (45756830)
SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
94500-6 (706163)
Inpatient Visit
IP (9201)
Pulmonary Disease
29 (38004472)
Thorax X-ray examination
GD1AA (2001303617)
Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
14804-9 (3022250)
Metamyelocytes/Leukocytes in Blood
28541-1 (3002179)
IgG [Mass/volume] in Serum or Plasma
2465-3 (3005719)
Office Visit
OMOP4822458 (581477)
Myelocytes/Leukocytes in Blood
26498-6 (3017181)
INR in Blood by Coagulation assay
34714-6 (3032080)
levofloxacin; inhalant, oral, parenteral
J01MA12 (21603019)
C reactive protein [Mass/volume] in Serum or Plasma
1988-5 (3020460)
Inpatient Hospital
21 (8717)
Differential panel, method unspecified - Blood
69738-3 (42870588)
prednisolone
A07EA01 (21600653)
General Surgery
2 (38004447)
prednisolone; oral, parenteral
H02AB06 (21602734)
Outpatient Hospital
22 (8756)
Amylase [Enzymatic activity/volume] in Serum or Plasma
1798-8 (3016771)
Promyelocytes/Leukocytes in Blood
26524-9 (3021440)
Internal Medicine
11 (38004456)
Rheumatology
66 (38004491)
Emergency Room and Inpatient Visit
ERIP (262)
Albumin [Mass/volume] in Serum or Plasma
1751-7 (3024561)
Sodium [Moles/volume] in Serum or Plasma
2951-2 (3019550)
Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
33762-6 (3029187)
Monocytes/Leukocytes in Blood
26485-3 (3019069)
Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma
1920-8 (3013721)
Basophils/Leukocytes in Blood
30180-4 (3022096)
Blood type and Crossmatch panel - Blood
34531-4 (3044640)
Eosinophils/Leukocytes in Blood
26450-7 (3006504)
Lymphocytes/Leukocytes in Blood
26478-8 (3002030)
Emergency Room Visit
ER (9203)
Blood group antibody screen [Presence] in Serum or Plasma
890-4 (3001079)
Blasts/Leukocytes in Blood
26446-5 (3025159)
Glucose [Moles/volume] in Serum or Plasma
14749-6 (3013826)
Neutrophils/Leukocytes in Blood
26511-6 (3018010)
Potassium [Moles/volume] in Serum or Plasma
2823-3 (3023103)
ABO and Rh group [Type] in Blood by Confirmatory method
77397-8 (46236098)
CBC panel - Blood by Automated count
58410-2 (40761511)
Bilirubin.total [Moles/volume] in Serum or Plasma
14631-6 (3006140)
Eosinophils [#/volume] in Blood
26449-9 (3013115)
enoxaparin; parenteral
B01AB05 (21600976)
Nuclear Ab [Titer] in Serum
29953-7 (3037522)
Monocytes [#/volume] in Blood
26484-6 (3001604)
Basophils [#/volume] in Blood
26444-0 (3006315)
Protein [Mass/volume] in Serum or Plasma
2885-2 (3020630)
Forced vital capacity [Volume] Respiratory system --post bronchodilation
19875-4 (3001668)
FEV1 --post bronchodilation
20155-8 (3023550)
FEV1/FVC --post bronchodilation
69970-2 (42868459)
FVC percent change Respiratory system
69982-7 (42868471)
FEV1 percent change
69983-5 (42868472)
Hematology
82 (38004501)
Lymphocytes [#/volume] in Blood
26474-7 (3019198)
FEV1/FVC
19926-5 (3011505)
Forced vital capacity [Volume] Respiratory system
19870-5 (3020158)
FEV1
20150-9 (3024653)
oxycodone; oral, parenteral
N02AA05 (21604260)
Troponin T.cardiac [Mass/volume] in Serum or Plasma
6598-7 (3019800)
Other specified chronic obstructive pulmonary disease
J44.8 (45586673)
Calcium [Moles/volume] in Serum or Plasma
2000-8 (3015377)
Erythrocyte [DistWidth] in Red Blood Cells
30385-9 (3002385)
pH of Serum or Plasma
2753-2 (3018418)
Creatinine [Moles/volume] in Serum or Plasma
14682-9 (3020564)
Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
30248-9 (3015399)
Supplier / Service Provider
OMOP5117446 (33004)
Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M
62238-1 (40764999)
Leukocytes [#/volume] in Blood
26464-8 (3010813)
Platelets [#/volume] in Blood
26515-7 (3007461)
Hemoglobin [Mass/volume] in Blood
718-7 (3000963)
MCV [Entitic mean volume] in Red Blood Cells
30428-7 (3024731)
Hematocrit [Volume Fraction] of Blood by calculation
20570-8 (3009542)
MCH [Entitic mass]
28539-5 (3035941)
Erythrocytes [#/volume] in Blood
26453-1 (3026361)
Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
1742-6 (3006923)
Neutrophils [#/volume] in Blood by Automated count
751-8 (3013650)
Ferritin [Mass/volume] in Serum or Plasma
2276-4 (3001122)
Outpatient Visit
OP (9202)
Urinalysis macro (dipstick) panel - Urine
24357-6 (3037467)
amoxicillin and beta-lactamase inhibitor; oral, parenteral
J01CR02 (21602863)
sulfamethoxazole and trimethoprim
J01EE01 (21602961)
Bacteria [#/volume] in Urine by Automated count
51480-2 (3031040)
MCHC [Entitic Mass/volume] in Red Blood Cells
28540-3 (3003338)
Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
6768-6 (3035995)
Chloride [Moles/volume] in Serum or Plasma
2075-0 (3014576)
Emergency Medicine
93 (38004510)
Spirometry for bronchospasm with prolonged evaluation after bronchodilator
113016006 (4010399)
furosemide; oral, parenteral
C03CA01 (21601518)
Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method
4537-7 (3013707)
Abdominal ultrasound examination
JN3AE (2001305555)
quetiapine; oral
N05AH04 (21604544)
Erythrocytes [Presence] in Urine by Automated
53292-9 (3041096)
Albumin [Presence] in Urine by Test strip
50949-7 (3029937)
Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
2324-2 (3026910)
Abnormal findings on diagnostic imaging of lung
R91 (45548995)
pH of Urine
2756-5 (3015736)
Ketones [Presence] in Urine by Test strip
2514-8 (3035350)
Laboratory Visit
OMOP4822461 (32036)
Esophagoscopy, gastroscopy and duodenoscopy
UJD10 (2001304788)
Glucose [Presence] in Urine by Test strip
25428-4 (3009261)
Upper gastrointestinal surgery
106 (44777669)
Nitrite [Presence] in Urine by Test strip
5802-4 (3021601)
Normoblasts [#/volume] in Blood
715-3 (3021589)
oxazepam; oral
N05BA04 (21604569)
pantoprazole; oral, parenteral
A02BC02 (21600097)
Leukocyte esterase [Presence] in Urine by Automated test strip
60026-2 (40763086)
cefalexin; oral
J01DB01 (21602870)
Chronic respiratory failure
J96.1 (45557632)
Spirometry
127783003 (4133840)
Atrial fibrillation and flutter
I48 (45596206)
Iron [Moles/volume] in Serum or Plasma
14798-3 (3022948)
Essential (primary) hypertension
I10 (45591453)
tiotropium bromide; inhalant
R03BB04 (21603296)
Protein [Presence] in Urine by Test strip
20454-5 (3014051)
Oncology Clinic/Center
261QX0200X (38004268)
warfarin; oral, parenteral
B01AA03 (21600965)
12 lead EKG panel
34534-8 (3044889)
Hemoglobin [Presence] in Urine by Test strip
5794-3 (3011397)
calcium (different salts in combination); oral
A12AA20 (21600872)
metoclopramide; oral, parenteral, rectal
A03FA01 (21600484)
Pharmacy visit
OMOP4822462 (581458)
Case Management Agency
251B00000X (38004193)
Orthopedic Surgery
20 (38004465)

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
52
50
11.50
48.07
2.1
1.5
0
0
52
50
11.50
48.07
2.1
1.5
0
0
52
50
11.50
48.07
2.1
1.5
0
0
52
50
11.50
48.07
2.1
1.5
0
0
101
216
5.62
46.48
3.8
1.9
1.13
3.31
ug/l
0.92
96
192
99
271
4.31
33.24
14.9
6.2
0
0
66
130
5.70
32.80
1.3
1.3
0
0
34
32
11.33
31.65
1.3
1.1
0
0
153
587
3.32
31.01
14.6
5.9
1.08
1.03
mmol/l
1.07
147
547
45
69
7.07
28.58
2.7
2.4
0
0
133
490
3.34
28.55
25.2
9.6
93.51
95.24
%
1.66
127
478
139
529
3.26
28.26
25.3
9.5
2.01
0.82
mmol/l
2.38
126
440
138
535
3.19
27.08
25.6
9.4
5.09
5.15
kpa
0.24
133
515
136
530
3.16
26.38
27.3
9.5
7.43
7.41
ph
1.88
87
302
245
1310
2.72
26.27
9.6
4.5
0
0
166
733
2.90
25.69
7.7
3.3
0.84
0.82
mmol/l
0.82
160
694
147
671
2.69
20.74
3.2
2.1
0
0
118
486
2.87
20.24
1.5
1.3
402.76
497.52
titre
0.21
29
105
76
253
3.37
18.72
2.0
1.7
0.94
1.58
g/l
1.47
70
232
68
225
3.34
16.86
2.2
2.1
1.68
1.49
g/l
0.65
55
198
36
75
5.10
16.63
2.1
1.5
0
0
41
97
4.52
16.29
8.6
3.3
0
0
83
325
2.87
15.37
7.9
3.1
7.43
7.42
ph
1.36
78
275
117
558
2.44
14.51
2.2
1.7
0
0
31
66
4.94
13.96
3.2
3.3
0
0
347
4156
0.45
13.77
61.6
26.7
4.19
4.47
e12/l
13.71
341
4055
347
4153
0.45
13.63
62.2
26.8
244.74
241.99
e9/l
0.30
342
4069
348
4156
0.45
13.41
61.6
26.8
8.25
6.84
e9/l
10.33
341
4057
31
69
4.73
13.25
2.2
1.4
161.00
151.72
au/ml
6
20
87
386
2.52
12.48
3.3
2.7
61.92
66.13
g/l
3.49
82
351
88
405
2.43
11.63
22.4
8.6
1.52
1.33
mmol/l
0.64
88
399
339
4045
0.49
11.59
24.0
12.5
29.27
26.18
u/l
1.95
333
3919
92
442
2.33
11.00
6.6
3.6
1.65
1.80
mmol/l
0.14
80
372
319
3866
0.51
10.95
5.8
6.1
2.55
2.61
mmol/l
0.56
297
3553
39
121
3.41
10.64
34.9
10.8
1.52
1.35
mmol/l
0.53
34
108
330
3946
0.51
10.56
40.2
15.8
0
0
212
1406
1.89
10.51
12.7
5.9
0
0
311
3780
0.52
10.29
5.1
5.3
1.36
1.42
mmol/l
1.65
292
3461
301
3693
0.53
10.24
8.3
6.8
41.49
39.87
mmol/mol
1.96
280
3434
93
463
2.24
10.18
8.0
3.7
7.37
7.38
ph
0.98
59
286
314
3798
0.53
10.05
5.2
5.4
4.40
4.49
mmol/l
0.83
294
3505
91
453
2.24
9.96
6.9
3.6
5.87
5.79
kpa
0.26
86
441
67
293
2.49
9.83
6.6
3.1
119.10
128.52
g/l
2.07
62
285
26
65
4.17
9.62
1.4
1.8
0.58
0.94
g/l
0.66
17
55
22
32
7.14
9.42
1.0
1.3
2.26
2.69
g/l
0.32
14
27
22
32
7.14
9.42
1.0
1.3
4.17
6.64
g/l
2.45
14
27
22
32
7.14
9.42
1.0
1.3
0.23
0.33
g/l
0.99
13
26
20
26
7.97
9.22
1.8
1.8
669.86
479.57
e6/l
0.48
14
21
316
3785
0.54
9.08
5.5
5.3
6.36
6.04
mmol/l
2.43
289
3448
79
386
2.24
9.00
6.3
4.6
1.34
0.89
%
1.09
52
137
25
64
4.06
8.98
1.4
1.3
996.05
2069.78
e6/l
1.67
20
40
76
366
2.27
8.96
6.3
4.4
1.26
0.50
%
1.52
47
121
98
523
2.09
8.94
2.4
1.7
0
0
79
393
2.20
8.60
26.2
9.6
0
0
21
33
6.60
8.57
1.0
1.3
0
0
22
53
4.30
8.54
1.5
1.5
0
0
27
76
3.70
8.52
1.6
1.2
192.24
297.97
u/ml
0.99
17
37
78
388
2.20
8.49
1.8
2.1
349.23
389.98
nmol/l
0.83
73
358
33
108
3.20
8.29
3.6
2.0
119.68
128.56
g/l
0.99
28
87
105
593
1.98
8.14
3.5
2.6
2.14
1.78
%
2.42
90
535
72
355
2.20
8.00
4.3
3.2
262.24
214.19
ng/l
0.26
67
324
24
65
3.83
7.99
3.6
2.6
6.39
4.92
e9/l
0.83
24
65
31
104
3.11
7.48
1.6
1.2
0
0
61
1149
0.47
7.42
3.0
3.4
0.61
0.81
ug/l
1.43
41
769
21
55
3.94
7.32
1.3
1.3
0
0
64
312
2.21
7.30
3.3
2.4
0
0
111
673
1.84
6.86
5.0
2.5
19.79
22.11
%
1.02
104
631
91
518
1.93
6.83
2.8
1.5
0
0
308
3632
0.60
6.75
4.9
4.5
1.46
1.28
mmol/l
3.96
287
3310
20
55
3.75
6.54
1.4
1.3
32467.64
27002.00
e6/l
0.09
11
27
88
1420
0.54
6.51
3.2
3.4
0
0
11
10
11.22
6.32
5.9
5.1
0
0
81
456
1.93
6.26
3.1
2.7
77.44
68.21
e9/l
1.10
62
346
61
312
2.09
6.16
7.6
4.1
135.49
86.59
ng/l
2.43
55
277
13
17
7.82
6.16
1.3
1.2
0
0
86
498
1.88
6.10
2.3
1.6
0
0
337
3861
0.60
6.10
49.0
17.8
38.23
26.46
mg/l
6.37
321
3220
140
936
1.69
6.09
3.2
1.7
2.01
1.55
mg/l
0.80
125
741
250
1931
1.59
6.07
24.7
6.9
1.19
1.21
mmol/l
3.99
239
1771
249
1930
1.58
5.90
13.6
6.2
8.20
9.07
%
4.24
242
1798
74
415
1.92
5.77
2.5
1.6
0
0
247
1920
1.57
5.72
12.6
6.1
63.52
58.16
%
7.89
240
1819
76
432
1.90
5.69
2.7
2.4
0.21
0.21
g/l
0.03
71
400
119
777
1.70
5.60
4.9
2.5
10.38
12.61
umol/l
3.38
113
730
250
1956
1.56
5.58
13.3
6.2
21.73
26.37
%
7.19
245
1847
17
37
4.72
5.53
1.2
1.3
0
0
35
148
2.47
5.53
2.4
1.6
3.67
9.34
iu/ml
10
39
28
106
2.74
5.50
2.2
1.8
0
0
47
228
2.17
5.43
9.9
3.3
0
0
112
725
1.70
5.43
5.1
2.5
2.12
2.26
g/l
1.66
104
674
66
364
1.94
5.41
6.9
4.7
0.13
0.15
%
0.12
39
114
246
1927
1.55
5.40
13.5
6.1
2.36
2.86
%
2.74
238
1793
243
1900
1.55
5.37
11.5
5.2
31.23
35.25
g/l
14.39
233
1777
307
3562
0.64
5.34
5.5
5.0
2.14
1.98
mu/l
0.94
287
3228
279
2251
1.55
5.33
12.7
6.9
10.24
12.09
umol/l
4.13
273
2155
87
528
1.79
5.28
3.6
3.0
5.00
8.26
umol/l
3.69
76
476
14
26
5.51
5.26
1.9
1.7
38.81
39.26
%
0.02
14
26
245
1926
1.54
5.24
13.8
6.1
0.52
0.65
%
3.53
237
1789
17
50
3.49
5.07
2.1
2.3
0
0
143
1940
0.63
5.06
4.3
5.9
1.69
2.78
ug/l
3.51
122
1733
175
1285
1.56
5.05
10.1
4.3
7.40
7.40
ph
0.33
142
935
25
94
2.75
4.99
4.4
2.7
65.64
59.80
%
1.59
25
94
10
13
7.82
4.87
2.9
2.3
71.09
104.29
ug/l
10
13
258
2074
1.51
4.83
11.5
5.9
0.67
0.61
e9/l
3.21
238
1755
18
57
3.24
4.81
2.1
2.7
0.80
1.40
g/24h
10
35
65
371
1.87
4.80
7.1
4.9
0.03
0.14
%
0.72
38
106
49
255
2.02
4.74
1.8
1.5
0
0
184
1385
1.52
4.67
4.9
3.3
41.62
34.64
u/l
0.94
175
1306
258
2083
1.50
4.67
11.4
5.9
0.04
0.04
e9/l
0.13
238
1766
33
149
2.30
4.54
4.9
3.5
7.82
3.26
ratio
0.30
25
84
260
2113
1.48
4.49
11.5
6.0
1.82
1.94
e9/l
0.34
241
1849
11
19
5.90
4.46
2.5
2.3
1477.91
783.16
u/ml
0.55
11
19
15
45
3.41
4.36
1.3
1.1
0
0
114
787
1.58
4.21
2.0
1.7
1112.59
1178.07
nmol/l
0.37
88
605
36
175
2.14
4.17
10.2
3.6
25.83
25.08
mmol/l
0.81
36
162
261
2143
1.46
4.16
13.2
6.1
0.21
0.20
e9/l
0.20
241
1856
17
57
3.05
4.16
1.8
1.7
0
0
99
670
1.60
3.96
1.6
1.3
38.80
27.83
iu/ml
0.62
35
212
122
1647
0.66
3.94
2.3
2.0
1.58
1.30
mmol/l
2.45
109
1368
14
43
3.32
3.93
1.7
2.8
576.36
1489.51
mg
1.04
14
43
240
2851
0.69
3.93
6.4
4.3
0.13
0
8
8
11
7.37
3.87
10.6
10.3
4.61
4.77
kpa
8
11
111
777
1.55
3.84
1.9
1.3
2.64
2.53
g/l
0.17
86
466
6
5
12.12
3.77
2.0
1.0
0
0
276
2319
1.43
3.72
18.7
9.8
5.37
4.21
e9/l
8.22
252
2010
257
2132
1.43
3.72
22.4
16.1
1.34
1.31
inr
0.44
222
1779
8
12
6.75
3.68
1.0
1.0
0
0
8
12
6.75
3.68
1.0
1.1
0
0
8
12
6.75
3.68
2.1
1.5
0
0
257
2144
1.41
3.54
25.9
7.6
1.20
1.21
mmol/l
2.32
231
1846
12
31
3.94
3.51
1.2
1.2
0
0
6
6
10.10
3.50
1.3
1.0
0
0
119
865
1.49
3.43
8.2
5.0
0
0
7
10
7.08
3.37
1.7
1.2
28.14
29.60
%
7
10
13
38
3.48
3.33
1.3
1.2
0
0
10
23
4.41
3.32
1.0
1.1
0
0
162
1257
1.43
3.31
5.2
3.4
0.51
0.56
e6/l
0.14
131
931
6
7
8.66
3.27
2.5
1.1
0
0
9
19
4.80
3.25
1.0
1.1
0
0
183
1456
1.41
3.24
4.3
3.3
2794.50
1659.99
ng/l
1.19
169
1251
11
29
3.85
3.20
3.3
2.3
0
0
7
11
6.44
3.19
1.1
1.2
0
0
7
11
6.44
3.19
1.1
1.2
0
0
13
40
3.31
3.16
2.3
1.5
0
0
17
67
2.59
3.16
2.1
2.2
29.29
33.19
pg
1.47
17
67
57
359
1.66
3.04
1.7
1.4
0
0
149
1157
1.41
2.99
3.1
2.3
3.18
2.95
mg/l
0.58
131
1003
5
5
10.08
2.98
1.4
1.0
0
0
5
5
10.08
2.98
1.4
1.0
0
0
15
58
2.64
2.90
1.3
1.1
2.50
8.45
u/ml
6
22
7
13
5.44
2.88
2.6
1.4
0
0
24
116
2.12
2.87
1.7
1.5
238.06
293.08
ug/g
0.53
15
66
17
71
2.44
2.83
1.1
1.0
0
0
12
44
2.77
2.56
2.8
2.0
11.15
10.65
%
0.22
12
44
86
620
1.47
2.56
1.5
1.3
15.72
7.58
u/ml
0.48
28
226
168
1361
1.35
2.55
3.4
2.2
347.24
265.60
u/l
0.25
161
1283
6
11
5.50
2.55
1.2
1.0
1648.67
1304.73
miu/ml
6
11
6
11
5.50
2.55
2.7
3.1
0
0
17
75
2.31
2.53
1.1
1.1
0
0
178
1461
1.34
2.47
5.4
3.5
52.84
103.19
e6/l
0.48
148
1128
6
12
5.05
2.41
1.0
1.2
0
0
129
1011
1.37
2.40
3.9
2.6
4.75
4.64
e6/l
0.05
122
922
5
8
6.30
2.37
3.6
2.5
2.00
2.38
%
5
8
116
899
1.38
2.31
6.6
4.2
754.01
352.01
ng/l
0.38
102
751
20
99
2.06
2.29
1.3
1.2
0
0
17
79
2.19
2.27
2.1
1.4
0
0
14
60
2.37
2.23
3.4
7.4
7.00
6.92
mmol/l
0.06
14
50
13
54
2.45
2.21
1.4
1.3
0
0
17
80
2.16
2.21
2.1
1.4
0
0
17
80
2.16
2.21
2.1
1.4
0
0
17
80
2.16
2.21
2.0
1.4
0
0
60
415
1.51
2.19
4.6
2.6
39.04
34.51
u/l
0.39
49
352
16
75
2.17
2.10
2.1
1.4
0
0
11
43
2.59
2.09
1.6
1.3
21.70
33.06
ng/l
0.69
11
43
18
89
2.06
2.08
1.2
1.4
146.08
271.68
miu/ml
5
40
11
44
2.53
2.02
2.9
2.0
2.11
0.56
mmol/l
0.56
11
44
9
32
2.85
2.01
6.0
3.1
0.56
0.84
index
9
32
37
234
1.63
1.99
2.2
1.6
0
0
11
45
2.48
1.94
1.3
1.2
0
0
263
2918
0.79
1.85
4.4
4.0
14.87
14.84
pmol/l
0.07
241
2620
110
876
1.33
1.82
5.1
3.1
507.31
545.00
mosm/kgh2o
1.26
103
764
48
333
1.49
1.76
9.6
3.9
1.20
1.23
mmol/l
2.64
43
286
55
397
1.43
1.66
3.0
2.5
7.93
7.69
ug/l
0.02
47
351
7
25
2.82
1.65
1.4
1.4
123.71
139.50
nmol/l
7
25
10
42
2.41
1.62
1.8
1.1
0
0
186
2117
0.81
1.53
6.1
3.9
0.00
0.00
estimate
-0.00
46
445
5
15
3.36
1.52
1.8
1.7
0
0
6
21
2.88
1.51
1.5
1.4
0
0
236
2616
0.81
1.50
5.7
3.4
103.22
54.07
u/l
2.29
223
2455
186
1619
1.24
1.49
6.5
4.1
82.61
114.87
e6/l
0.37
152
1167
148
1257
1.25
1.48
4.5
3.4
0
0
14
73
1.94
1.45
2.3
1.3
74.71
59.37
mmol/l
0.41
14
62
6
22
2.75
1.44
2.0
3.1
359.83
478.93
min
6
14
27
175
1.57
1.37
1.5
1.5
0.23
0.31
mg/l
10
81
9
42
2.16
1.34
1.2
1.2
0
0
9
43
2.11
1.31
1.8
2.0
0
0
13
230
0.55
1.30
1.8
1.9
3.65
3.48
mmol/l
8
175
193
2161
0.83
1.29
6.5
4.0
0.00
0.72
estimate
0.51
42
424
17
99
1.74
1.28
1.1
1.2
0
0
44
322
1.40
1.27
6.7
3.6
0
0
9
45
2.02
1.24
1.2
1.2
0
0
161
1407
1.21
1.21
5.1
2.5
0
0
8
38
2.12
1.19
1.1
1.1
0
0
165
1449
1.21
1.18
6.2
3.5
2.31
2.35
mmol/l
1.97
152
1299
134
1538
0.82
1.13
5.0
3.8
0.60
0
5
7
30
2.35
1.12
1.6
3.6
16.97
16.84
%
7
30
7
139
0.50
1.11
2.6
1.7
0
0
5
21
2.39
1.09
1.4
1.2
0
0
193
2136
0.84
1.08
6.3
4.0
23.69
3.60
estimate
0.39
48
451
7
32
2.20
1.08
1.1
1.2
90.71
95.69
pmol/l
7
32
15
240
0.61
1.06
1.3
1.2
0
0
271
2505
1.18
1.06
20.0
5.5
7.55
6.77
mmol/l
5.56
266
2385
142
1607
0.84
1.02
6.0
3.9
0.07
0.01
estimate
0.55
42
377
95
1115
0.82
1.00
1.5
1.4
0
0
13
76
1.73
0.99
9.3
3.3
12.26
8.74
pmol/l
0.54
13
76
13
76
1.73
0.99
1.6
1.2
147.58
31.25
u/l
0.44
13
65
9
49
1.85
0.99
6.3
3.3
13.44
12.28
index
9
32
130
1139
1.19
0.94
6.8
2.9
361.74
358.87
umol/l
0.10
110
994
29
392
0.72
0.92
3.0
2.0
0.00
0.04
estimate
5
83
6
28
2.16
0.92
3.5
2.5
0
0
47
369
1.30
0.91
2.4
1.4
0
0
6
30
2.01
0.87
1.2
1.1
0
0
8
45
1.79
0.84
1.0
1.1
0
0
8
46
1.75
0.83
1.0
1.1
0
0
26
189
1.40
0.83
1.6
1.2
0
0
6
32
1.89
0.82
1.2
1.4
0
0
6
32
1.89
0.82
1.2
1.1
0
0
104
908
1.18
0.79
1.8
1.8
551.38
5284447.43
pmol/l
0.50
84
757
7
40
1.76
0.71
1.3
1.1
0
0
7
41
1.72
0.70
1.3
1.3
nmol/l
0
0
9
59
1.53
0.68
10.7
2.0
12.44
10.56
mmol/l
9
59
17
120
1.43
0.65
39.9
10.5
0
0
134
1212
1.14
0.65
13.4
6.4
0
0
5
29
1.73
0.64
2.8
1.6
62.00
84.55
umol/l
5
29
59
503
1.20
0.60
4.4
3.0
5.67
4.62
e9/l
0.80
50
428
109
1204
0.88
0.56
6.1
3.9
0.00
0.01
estimate
0.78
44
405
6
37
1.63
0.55
1.7
3.3
6.88
8.24
mmol/l
6
37
84
744
1.16
0.55
5.3
3.3
1.78
1.70
e6/l
0.05
45
397
64
555
1.18
0.55
1.5
1.3
0
0
9
136
0.66
0.52
2.4
1.9
25.67
41.68
nmol/l
9
127
28
346
0.80
0.52
3.2
2.6
5.92
6.03
ph
0.37
19
244
6
40
1.51
0.51
1.2
1.4
0
0
105
1155
0.88
0.51
5.5
3.4
0.00
0.08
estimate
0.60
40
350
16
118
1.37
0.50
1.2
1.1
0
0
47
400
1.19
0.50
7.7
4.3
7.33
7.35
ph
0.18
41
277
6
41
1.47
0.50
2.8
1.3
0
0
12
167
0.71
0.50
1.2
1.1
0
0
27
217
1.26
0.49
1.2
1.2
28.04
133.99
u/ml
8
85
189
1776
1.10
0.48
3.6
2.4
72.40
77.39
nmol/l
1.94
175
1561
7
47
1.50
0.47
1.6
1.1
0
0
20
156
1.29
0.45
2.8
3.1
885.40
278.59
mg/l
10
59
93
843
1.13
0.45
1.3
1.2
2.81
1.31
u/ml
0.55
28
235
148
1585
0.91
0.44
2.4
2.2
0
0
6
91
0.66
0.42
1.3
3.6
3617.32
478.98
u/ml
6
83
268
2787
0.92
0.42
7.5
4.6
2.23
0
7
8
112
0.71
0.37
1.0
1.1
1.47
1.55
g/l
8
112
6
42
1.43
0.35
1.0
1.7
264.67
280.20
mosm/kgh2o
6
30
9
126
0.71
0.35
4.3
5.2
0
0
6
45
1.34
0.34
1.3
1.1
0
0
194
1853
1.08
0.33
5.8
3.0
325.41
138.35
ug/l
2.90
182
1714
89
958
0.91
0.30
5.7
4.0
0.14
0
14
124
1315
0.92
0.30
2.0
1.8
17.73
20.40
nmol/l
1.56
112
1092
10
75
1.34
0.30
1.4
1.3
0
0
7
56
1.25
0.29
1.1
1.1
0
0
9
118
0.76
0.27
1.0
1.1
0.97
0.89
g/l
9
118
184
1913
0.94
0.26
2.6
2.2
92.80
94.35
pmol/l
0.22
115
1036
44
483
0.90
0.23
1.5
1.3
0
0
7
91
0.77
0.22
1.3
1.3
0
0
0
11
0.00
0.21
0.0
4.5
7.15
0
11
0
10
0.00
0.21
0.0
1.4
0
0
0
12
0.00
0.21
0.0
1.3
0.00
0
12
0
13
0.00
0.21
0.0
1.1
0.05
0
6
0
14
0.00
0.20
0.0
1.1
0
0
17
197
0.86
0.20
1.4
1.3
0
0
48
444
1.09
0.19
2.1
2.4
148.73
119.54
ug/g
0.38
39
356
9
79
1.14
0.15
2.2
1.3
0
0
178
1740
1.04
0.12
6.8
4.1
79.60
47.60
ng/l
0.49
155
1313
20
218
0.91
0.10
2.9
2.9
0
0
143
1461
0.97
0.09
5.4
4.0
28.60
9.97
mg/mmol
1.23
102
923
311
3134
0.98
0.06
17.5
8.4
89.53
79.98
u/l
2.77
304
2945
196
1937
1.02
0.06
5.3
2.9
estimate
0
0
22
209
1.06
0.04
2.6
2.4
0
0
30
291
1.03
0.02
1.3
1.2
0
0
148
1468
1.01
0.02
4.4
3.3
6.70
7.78
mmol/l
2.61
130
1215
167
1682
0.99
0.02
5.1
3.6
6.17
6.19
ph
0.06
107
949
17
177
0.96
0.01
2.9
1.9
0
0
141
1417
0.99
0.00
4.5
3.4
119.04
56.20
mg/l
1.09
100
935
48
485
0.99
0.00
2.7
4.4
4.81
39.26
ug/l
1.30
42
402
55
545
1.01
0.00
1.3
1.4
0
0
29
288
1.01
0.00
1.4
1.4
0
0
181
1811
1.00
0.00
25.5
11.7
0.00
0.00
e9/l
0.32
154
1469
92
924
0.99
0.00
6.2
4.2
15.27
1.02
kg/l
0.49
71
627
88
876
1.01
0.00
3.1
3.1
2.49
2.45
mmol/l
1.56
79
784
0
7
0.00
-0.00
0.0
1.0
0
0
0
6
0.00
-0.00
0.0
1.0
0
0
0
6
0.00
-0.00
0.0
2.0
0.58
0
6
0
9
0.00
-0.00
0.0
1.8
16.73
0
9
0
5
0.00
-0.00
0.0
1.0
0
0
0
7
0.00
-0.00
0.0
1.0
64.00
0
7

Mortality – FinRegistry

Association

Association between endpoint J10_ARDS and mortality.

Females

Parameter HR [95% CI] p-value
J10_ARDS 4.114 [2.99, 5.67] < 0.001
Birth year 0.993 [0.98, 1.0] 0.123

During the follow-up period (1.1.1998 — 31.12.2019), 380 out of 840 females with J10_ARDS died.

Males

Parameter HR [95% CI] p-value
J10_ARDS 3.869 [3.11, 4.82] < 0.001
Birth year 0.988 [0.98, 1.0] 0.02

During the follow-up period (1.1.1998 — 31.12.2019), 581 out of 1115 males with J10_ARDS died.

Mortality risk

Mortality risk for people of age

years, who have J10_ARDS.

N-year risk Females Males
1 0.343% 0.847%
5 2.574% 4.935%
10 6.118% 11.15%
15 11.445% 19.998%
20 18.726% 31.948%

Relationships between endpoints

Index endpoint: J10_ARDS – Adult respiratory distress syndrome

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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