No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
554 |
4. Check minimum number of eventsNone |
554 |
5. Include endpointsNone |
554 |
6. Filter based on genotype QC (FinnGen only) |
471 |
Control definitions (FinnGen only)
- Control exclude
- J10_INTERSTITIUM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF6
- Parent code in ICD-10
- J80-J84
- Name in latin
- Syndroma dyspnoicum adultorum
Similar endpoints
↥List of similar endpoints to
Adult respiratory distress syndrome
based on the number of shared cases.
Similar with more cases:
- Other respiratory diseases principally affecting the interstitium
- Condition for Implicit Sepsis (Organ dysfunction codes)
- Condition for Implicit Sepsis (Organ dysfunction codes), including avohilmo
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4454 | 1675 | 2699 |
| Only index persons | 2675 | 1057 | 1618 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.05 | 0.08 |
| Only index persons | 0.05 | 0.04 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 64.11 | 63.05 | 64.59 |
| Only index persons | 63.57 | 61.33 | 65.04 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 471 | 171 | 300 |
| Unadjusted period prevalence (%) | 0.11 | 0.06 | 0.14 |
| Median age at first event (years) | 63.42 | 55.98 | 67.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 496
- Matched controls
- 4960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J80
ICD-10 Finland
Adult respiratory distress syndrome
+∞
307.7
474
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
6.2
89.3
313
1077
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.0
83.4
219
580
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.8
65.6
121
225
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.8
60.9
137
307
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
9.1
58.7
78
100
WX730
NOMESCO Finland
Conventional respirator
19.0
52.1
42
24
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
515.0
48.2
47
*
WX872
NOMESCO Finland
Intensive care
6.8
48.2
83
142
GD1AD
NOMESCO Finland
Thorax CT examination
5.7
38.3
79
160
GBB00
NOMESCO Finland
Tracheostomy
15.1
37.7
34
24
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
+∞
34.8
33
*
J96.0
ICD-10 Finland
Acute respiratory failure
12.5
33.7
34
29
TK800
NOMESCO Finland
Hemodialysis
9.2
32.7
41
48
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.6
31.2
82
203
TGC00
NOMESCO Finland
Bronchial lavation
7.6
28.0
41
58
WX892
NOMESCO Finland
Monitored bed care
4.3
26.6
77
205
L04AA06
ATC
mycophenolic acid; systemic
10.2
25.2
29
30
ZXD05
NOMESCO Finland
Urgent procedure
2.7
24.9
207
1038
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.5
24.6
65
161
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
7.3
24.5
37
54
A41.9
ICD-10 Finland
Sepsis, unspecified
5.4
24.3
50
100
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.7
24.2
61
145
5185A
ICD-9 Finland
Other diseases of lung, Pulmonary insufficiency following trauma and surgery
+∞
23.1
22
*
J01MA12
ATC
levofloxacin; systemic
2.7
21.2
144
644
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
+∞
19.9
19
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.8
19.1
36
66
WX882
NOMESCO Finland
High dependency care
6.0
18.3
33
58
H02AB06
ATC
prednisolone; systemic
2.3
18.1
279
1780
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
17.9
92
352
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
17.7
145
704
C03CA01
ATC
furosemide; systemic
2.3
17.5
226
1336
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
17.5
97
387
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
17.0
98
398
WX725
NOMESCO Finland
Noninvasive ventilation
4.0
16.9
50
134
J81
ICD-10 Finland
Pulmonary oedema
+∞
16.8
16
*
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.1
15.9
28
48
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
15.7
15.0
24
16
JN4BD
NOMESCO Finland
Extensive body CT
2.8
14.8
81
319
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.8
14.7
83
332
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.8
14.6
23
35
A98
ICPC
Health maint/preventive medicine
0.5
14.5
334
4071
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
13.9
276
1874
R50.9
ICD-10 Finland
Fever, unspecified
2.5
13.7
100
455
J01MA14
ATC
moxifloxacin; systemic
2.9
13.6
71
272
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
13.4
76
305
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
13.0
84
359
127
Kela drug reimbursment
Transplant complication
11.4
12.6
23
21
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
17.9
12.6
19
11
J96.1
ICD-10 Finland
Chronic respiratory failure
4.8
12.3
28
61
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.7
12.2
40
115
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
21.9
12.1
17
8
WX722
NOMESCO Finland
PEEP
3.3
11.8
47
154
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.5
11.6
42
129
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
11.4
61
236
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
11.4
117
612
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.9
11.3
25
53
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.7
11.3
21
38
XG410
NOMESCO Finland
Flow-volume spirometry
3.9
11.2
33
88
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.9
10.6
32
87
N05AA02
ATC
levomepromazine; systemic
3.7
10.4
34
98
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
4.6
10.1
24
54
A10AC01
ATC
insulin (human); parenteral
2.7
10.0
58
234
WX704
NOMESCO Finland
Intubation
2.9
10.0
50
187
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
9.9
36
111
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.3
9.8
38
122
L04AX01
ATC
azathioprine; systemic
4.2
9.8
26
64
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.1
9.7
27
69
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.5
9.6
63
270
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
9.6
137
805
Z2446
NOMESCO Finland
Social worker
2.9
9.5
45
163
B01AA03
ATC
warfarin; systemic
2.0
9.5
131
762
WX726
NOMESCO Finland
High-flow oxygen therapy
+∞
9.4
9
*
N03AX16
ATC
[U] pregabalin
2.0
9.3
125
718
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.8
9.3
28
76
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
9.2
33
101
A01AB10
ATC
natamycin; local oral
4.6
9.2
22
50
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
9.1
128
747
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
8.9
95
502
Z3226
NOMESCO Finland
Physiotherapist
2.1
8.9
102
554
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
8.6
91
479
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
8.5
157
998
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.4
8.5
30
91
TQW11
NOMESCO Finland
Vacuum treatment of wound
4.6
8.4
20
45
R06.0
ICD-10 Finland
Dyspnoea
1.8
8.4
154
977
ZX120
NOMESCO Finland
Intravenous
2.4
8.4
62
281
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
7.7
8.2
18
24
A10AB05
ATC
insulin aspart; parenteral
2.6
8.2
49
201
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
17.5
8.1
12
7
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
8.0
136
841
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.3
7.8
20
48
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
7.8
29
91
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
3.5
7.6
26
77
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.9
7.6
22
58
J15.8
ICD-10 Finland
Other bacterial pneumonia
9.6
7.3
14
15
284
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
7.3
7
*
R03BB04
ATC
tiotropium bromide; inhalant
2.1
7.2
72
369
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.0
7.2
20
51
XG466
NOMESCO Finland
Sleep oxymetry
3.5
7.2
25
75
L04AD01
ATC
ciclosporin; systemic
6.7
7.2
17
26
RS220, ,
NOMESCO Finland
10.2
7.1
13
13
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.3
7.1
18
43
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.5
7.1
47
203
K85
ICD-10 Finland
Acute pancreatitis
4.5
7.0
17
39
K65.0
ICD-10 Finland
Acute peritonitis
7.7
6.9
15
20
J12.8
ICD-10 Finland
Other viral pneumonia
8.4
6.9
14
17
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
6.8
78
422
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.0
6.7
29
100
GX2D5
NOMESCO Finland
Sleep oximetry
22.9
6.7
9
*
H02AB04
ATC
methylprednisolone; systemic
2.0
6.7
81
446
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
5.6
6.7
18
33
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.5
6.7
42
177
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.4
6.6
23
69
Z94.0
ICD-10 Finland
Kidney transplant status
10.2
6.6
12
12
J93.8
ICD-10 Finland
Other pneumothorax
10.2
6.6
12
12
N17.8
ICD-10 Finland
Other acute renal failure
7.0
6.6
15
22
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.0
6.5
28
96
Z49.1
ICD-10 Finland
Extracorporeal dialysis
6.3
6.5
16
26
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.5
6.4
14
19
137
Kela drug reimbursment
Uraemia requiring dialysis
9.4
6.3
12
13
JN4AD
NOMESCO Finland
Body CT examination
2.0
6.3
68
359
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
6.3
25
82
356
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
6.3
6
*
P01BA02
ATC
hydroxychloroquine; oral
2.4
6.2
41
177
C07AB07
ATC
bisoprolol; oral
1.6
6.2
262
2042
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.4
6.1
41
178
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
6.1
36
147
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
8.8
6.1
12
14
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.8
6.1
14
21
ZXD00
NOMESCO Finland
Emergency procedure
3.4
6.1
21
63
J12.9
ICD-10 Finland
Viral pneumonia, unspecified
10.2
6.1
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
104
115
11.18
88.74
2.2
1.5
—
—
—
0
0
100
109
11.24
86.11
2.2
1.5
—
—
—
0
0
56
32
19.60
69.82
2.2
1.7
—
—
—
0
0
72
79
10.49
61.05
2.1
1.6
—
—
—
0
0
76
93
9.47
59.34
2.1
1.5
—
—
—
0
0
64
71
10.20
53.66
1.9
1.6
—
—
—
0
0
56
54
11.56
51.75
2.1
1.5
—
—
—
0
0
66
86
8.70
48.76
2.0
1.6
—
—
—
0
0
64
85
8.50
46.50
2.0
1.5
—
—
—
0
0
101
216
5.62
46.48
3.8
1.9
1.13
3.31
ug/l
0.92
96
192
51
56
10.04
42.88
2.1
1.5
—
—
—
0
0
44
46
10.40
38.24
2.1
1.7
—
—
—
0
0
42
43
10.58
37.02
2.1
1.8
—
—
—
0
0
77
168
5.24
34.21
3.8
3.2
—
—
—
0
0
153
587
3.32
31.01
14.6
5.9
1.08
1.03
mmol/l
1.07
147
547
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
68
146
5.24
30.67
5.8
2.4
0.32
0.35
iu/ml
0.38
48
74
133
490
3.34
28.55
25.2
9.6
93.51
95.24
%
1.66
127
478
41
57
7.75
28.40
1.3
1.4
—
—
—
0
0
139
529
3.26
28.26
25.3
9.5
2.01
0.82
mmol/l
2.38
126
440
49
85
6.29
27.66
14.0
6.6
280.46
168.00
iu/ml
0.61
13
11
138
535
3.19
27.08
25.6
9.4
5.09
5.15
kpa
0.24
133
515
178
811
2.86
26.03
3.4
1.8
—
—
—
0
0
166
733
2.90
25.69
7.7
3.3
0.84
0.82
mmol/l
0.82
160
694
139
574
2.98
24.13
3.0
1.9
—
—
—
0
0
30
35
9.06
23.88
2.2
1.6
—
—
—
0
0
30
35
9.06
23.88
2.2
1.6
—
—
—
0
0
30
35
9.06
23.88
2.2
1.6
—
—
—
0
0
142
610
2.86
22.78
2.8
1.8
—
—
—
0
0
29
35
8.74
22.47
2.1
1.5
—
—
—
0
0
93
316
3.39
22.35
2.1
1.6
—
—
—
0
0
80
281
3.20
18.03
7.1
3.1
2.88
2.07
mmol/l
1.19
66
213
44
102
4.64
17.94
2.4
1.4
—
—
—
0
0
68
225
3.34
16.86
2.2
2.1
1.68
1.49
g/l
0.65
55
198
23
17
14.12
13.85
1.7
1.1
—
—
—
0
0
347
4156
0.45
13.77
61.6
26.7
4.19
4.47
e12/l
13.71
341
4055
347
4153
0.45
13.63
62.2
26.8
244.74
241.99
e9/l
0.30
342
4069
348
4156
0.45
13.41
61.6
26.8
8.25
6.84
e9/l
10.33
341
4057
31
69
4.73
13.25
2.2
1.4
161.00
151.72
au/ml
—
6
20
87
386
2.52
12.48
3.3
2.7
61.92
66.13
g/l
3.49
82
351
41
121
3.60
12.06
2.7
1.5
—
—
—
0
0
111
561
2.26
11.84
7.4
4.3
302.24
240.02
u/l
3.14
105
533
88
405
2.43
11.63
22.4
8.6
1.52
1.33
mmol/l
0.64
88
399
339
4045
0.49
11.59
24.0
12.5
29.27
26.18
u/l
1.95
333
3919
303
3748
0.51
11.52
36.3
17.2
76.47
77.68
ml/min/173m2
0.35
285
3505
92
442
2.33
11.00
6.6
3.6
1.65
1.80
mmol/l
0.14
80
372
319
3866
0.51
10.95
5.8
6.1
2.55
2.61
mmol/l
0.56
297
3553
21
22
9.91
10.85
2.6
1.6
—
—
—
0
0
30
78
4.03
10.55
1.5
1.2
—
—
—
0
0
21
24
9.08
10.37
2.6
1.6
—
—
—
0
0
311
3780
0.52
10.29
5.1
5.3
1.36
1.42
mmol/l
1.65
292
3461
301
3693
0.53
10.24
8.3
6.8
41.49
39.87
mmol/mol
1.96
280
3434
20
22
9.42
10.10
2.4
1.6
—
—
—
0
0
20
22
9.42
10.10
2.4
1.6
—
—
—
0
0
20
22
9.42
10.10
2.4
1.6
—
—
—
0
0
20
22
9.42
10.10
2.4
1.6
—
—
—
0
0
314
3798
0.53
10.05
5.2
5.4
4.40
4.49
mmol/l
0.83
294
3505
91
453
2.24
9.96
6.9
3.6
5.87
5.79
kpa
0.26
86
441
67
293
2.49
9.83
6.6
3.1
119.10
128.52
g/l
2.07
62
285
21
27
8.07
9.71
2.6
1.6
—
—
—
0
0
19
21
9.36
9.60
1.6
2.0
—
—
—
0
0
18
19
9.78
9.34
2.5
1.6
—
—
—
0
0
18
19
9.78
9.34
2.5
1.6
—
—
—
0
0
20
26
7.97
9.22
1.8
1.8
669.86
479.57
e6/l
0.48
14
21
18
20
9.29
9.10
2.5
1.6
—
—
—
0
0
316
3785
0.54
9.08
5.5
5.3
6.36
6.04
mmol/l
2.43
289
3448
25
64
4.06
8.98
1.4
1.3
996.05
2069.78
e6/l
1.67
20
40
27
76
3.70
8.52
1.6
1.2
192.24
297.97
u/ml
0.99
17
37
78
388
2.20
8.49
1.8
2.1
349.23
389.98
nmol/l
0.83
73
358
33
108
3.20
8.29
3.6
2.0
119.68
128.56
g/l
0.99
28
87
20
46
4.49
8.22
1.5
1.3
—
—
—
0
0
72
355
2.20
8.00
4.3
3.2
262.24
214.19
ng/l
0.26
67
324
34
121
2.94
7.42
1.7
1.6
—
—
—
0
0
61
1149
0.47
7.42
3.0
3.4
0.61
0.81
ug/l
1.43
41
769
111
673
1.84
6.86
5.0
2.5
19.79
22.11
%
1.02
104
631
308
3632
0.60
6.75
4.9
4.5
1.46
1.28
mmol/l
3.96
287
3310
99
1552
0.55
6.67
4.0
4.8
23.48
21.48
%
0.62
43
781
20
55
3.75
6.54
1.4
1.3
32467.64
27002.00
e6/l
0.09
11
27
34
132
2.69
6.35
1.4
1.2
—
—
—
0
0
61
312
2.09
6.16
7.6
4.1
135.49
86.59
ng/l
2.43
55
277
337
3861
0.60
6.10
49.0
17.8
38.23
26.46
mg/l
6.37
321
3220
140
936
1.69
6.09
3.2
1.7
2.01
1.55
mg/l
0.80
125
741
250
1931
1.59
6.07
24.7
6.9
1.19
1.21
mmol/l
3.99
239
1771
14
21
6.83
6.07
2.9
5.6
—
—
—
0
0
26
90
2.99
5.98
1.5
1.2
—
—
—
0
0
31
119
2.71
5.92
1.6
1.3
—
—
—
0
0
26
92
2.93
5.76
1.4
1.3
—
—
—
0
0
76
432
1.90
5.69
2.7
2.4
0.21
0.21
g/l
0.03
71
400
29
110
2.74
5.67
1.9
1.4
—
—
—
0
0
119
777
1.70
5.60
4.9
2.5
10.38
12.61
umol/l
3.38
113
730
35
148
2.47
5.53
2.4
1.6
3.67
9.34
iu/ml
—
10
39
112
725
1.70
5.43
5.1
2.5
2.12
2.26
g/l
1.66
104
674
243
1900
1.55
5.37
11.5
5.2
31.23
35.25
g/l
14.39
233
1777
307
3562
0.64
5.34
5.5
5.0
2.14
1.98
mu/l
0.94
287
3228
279
2251
1.55
5.33
12.7
6.9
10.24
12.09
umol/l
4.13
273
2155
87
528
1.79
5.28
3.6
3.0
5.00
8.26
umol/l
3.69
76
476
16
35
4.69
5.22
1.3
1.1
—
—
—
0
0
18
54
3.42
5.21
1.2
1.2
1.17
3.24
u/ml
—
6
17
17
50
3.49
5.07
2.7
4.1
—
—
—
0
0
143
1940
0.63
5.06
4.3
5.9
1.69
2.78
ug/l
3.51
122
1733
24
88
2.82
5.01
1.9
1.4
—
—
—
0
0
24
88
2.82
5.01
1.9
1.4
—
—
—
0
0
10
13
7.82
4.87
2.9
2.3
71.09
104.29
ug/l
—
10
13
18
57
3.24
4.81
1.0
1.2
—
—
—
0
0
36
166
2.26
4.72
1.4
2.3
41.30
38.53
u/l
0.20
30
147
184
1385
1.52
4.67
4.9
3.3
41.62
34.64
u/l
0.94
175
1306
13
26
5.10
4.66
1.6
1.7
—
—
—
0
0
13
26
5.10
4.66
1.6
1.7
—
—
—
0
0
33
149
2.30
4.54
4.9
3.5
7.82
3.26
ratio
0.30
25
84
11
19
5.90
4.46
2.5
2.3
1477.91
783.16
u/ml
0.55
11
19
57
325
1.85
4.23
2.0
1.4
—
—
—
0
0
14
41
3.48
4.21
1.2
1.1
—
—
—
0
0
114
787
1.58
4.21
2.0
1.7
1112.59
1178.07
nmol/l
0.37
88
605
36
175
2.14
4.17
10.2
3.6
25.83
25.08
mmol/l
0.81
36
162
10
17
5.98
4.15
2.5
3.1
112.30
94.76
%
—
10
17
8
10
8.11
4.07
1.9
1.4
—
—
—
0
0
8
10
8.11
4.07
1.1
1.0
—
—
—
0
0
99
670
1.60
3.96
1.6
1.3
38.80
27.83
iu/ml
0.62
35
212
122
1647
0.66
3.94
2.3
2.0
1.58
1.30
mmol/l
2.45
109
1368
14
43
3.32
3.93
1.7
2.8
576.36
1489.51
mg
1.04
14
43
8
11
7.37
3.87
10.6
10.3
4.61
4.77
kpa
—
8
11
7
8
8.85
3.78
1.0
1.8
—
—
—
0
0
16
55
2.97
3.77
1.9
1.4
—
—
—
0
0
16
55
2.97
3.77
1.9
1.4
—
—
—
0
0
16
55
2.97
3.77
1.9
1.4
—
—
—
0
0
276
2319
1.43
3.72
18.7
9.8
5.37
4.21
e9/l
8.22
252
2010
257
2132
1.43
3.72
22.4
16.1
1.34
1.31
inr
0.44
222
1779
36
184
2.03
3.68
4.1
1.7
—
—
—
0
0
16
56
2.92
3.66
1.9
1.4
—
—
—
0
0
16
57
2.87
3.55
1.9
1.4
—
—
—
0
0
16
57
2.87
3.55
1.9
1.4
—
—
—
0
0
257
2144
1.41
3.54
25.9
7.6
1.20
1.21
mmol/l
2.32
231
1846
24
106
2.33
3.51
1.5
1.3
—
—
—
0
0
162
1257
1.43
3.31
5.2
3.4
0.51
0.56
e6/l
0.14
131
931
42
237
1.84
3.25
2.2
1.5
—
—
—
0
0
9
19
4.80
3.25
1.0
1.1
—
—
—
0
0
70
457
1.62
3.24
6.2
3.5
—
—
—
0
0
183
1456
1.41
3.24
4.3
3.3
2794.50
1659.99
ng/l
1.19
169
1251
7
11
6.44
3.19
1.1
1.2
—
—
—
0
0
17
67
2.59
3.16
2.1
2.2
29.29
33.19
pg
1.47
17
67
149
1157
1.41
2.99
3.1
2.3
3.18
2.95
mg/l
0.58
131
1003
11
32
3.49
2.91
1.6
1.3
—
—
—
0
0
15
58
2.64
2.90
1.3
1.1
2.50
8.45
u/ml
—
6
22
10
27
3.76
2.89
2.3
1.9
—
—
—
0
0
24
116
2.12
2.87
1.7
1.5
238.06
293.08
ug/g
0.53
15
66
31
167
1.91
2.78
3.1
1.6
—
—
—
0
0
6
10
6.06
2.70
12.0
10.7
9.07
10.74
%
—
6
10
10
30
3.38
2.61
1.1
1.0
—
—
—
0
0
86
620
1.47
2.56
1.5
1.3
15.72
7.58
u/ml
0.48
28
226
168
1361
1.35
2.55
3.4
2.2
347.24
265.60
u/l
0.25
161
1283
6
11
5.50
2.55
1.5
1.2
—
—
—
0
0
6
11
5.50
2.55
1.2
1.0
1648.67
1304.73
miu/ml
—
6
11
178
1461
1.34
2.47
5.4
3.5
52.84
103.19
e6/l
0.48
148
1128
129
1011
1.37
2.40
3.9
2.6
4.75
4.64
e6/l
0.05
122
922
5
8
6.30
2.37
1.2
1.3
—
—
—
0
0
13
52
2.54
2.37
1.2
1.1
—
—
—
0
0
16
326
0.47
2.34
2.1
2.1
3.50
3.52
ratio
0.02
11
272
116
899
1.38
2.31
6.6
4.2
754.01
352.01
ng/l
0.38
102
751
11
40
2.79
2.28
1.0
1.3
—
—
—
0
0
14
60
2.37
2.23
3.4
7.4
7.00
6.92
mmol/l
0.06
14
50
60
415
1.51
2.19
4.6
2.6
39.04
34.51
u/l
0.39
49
352
18
89
2.06
2.08
1.2
1.4
146.08
271.68
miu/ml
—
5
40
6
15
4.04
2.04
1.7
1.1
—
—
—
0
0
11
44
2.53
2.02
2.9
2.0
2.11
0.56
mmol/l
0.56
11
44
8
26
3.11
2.02
3.0
1.2
—
—
—
0
0
9
32
2.85
2.01
6.0
3.1
0.56
0.84
index
—
9
32
35
540
0.62
2.00
5.8
5.1
30.00
31.49
%
0.52
30
344
7
21
3.37
1.97
1.1
1.1
—
—
—
0
0
45
300
1.55
1.96
2.1
1.6
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
11
4.58
1.94
1.6
3.1
329.46
130.18
%
—
5
11
7
22
3.21
1.88
1.0
1.2
80.86
19.35
u/l
—
7
17
263
2918
0.79
1.85
4.4
4.0
14.87
14.84
pmol/l
0.07
241
2620
7
23
3.07
1.80
1.0
1.2
121.57
82.94
u/l
—
7
18
8
29
2.79
1.80
1.3
3.6
1.00
0.90
%
—
8
29
8
29
2.79
1.80
1.9
1.3
—
—
—
0
0
48
333
1.49
1.76
9.6
3.9
1.20
1.23
mmol/l
2.64
43
286
7
24
2.94
1.73
2.0
1.3
—
—
—
0
0
7
24
2.94
1.73
2.0
1.3
—
—
—
0
0
55
397
1.43
1.66
3.0
2.5
7.93
7.69
ug/l
0.02
47
351
13
63
2.09
1.61
1.2
1.4
—
—
—
0
0
186
2117
0.81
1.53
6.1
3.9
0.00
0.00
estimate
-0.00
46
445
236
2616
0.81
1.50
5.7
3.4
103.22
54.07
u/l
2.29
223
2455
19
109
1.77
1.49
1.5
1.6
—
—
—
0
0
7
28
2.52
1.45
2.0
1.3
—
—
—
0
0
7
29
2.43
1.39
2.0
1.3
—
—
—
0
0
27
175
1.57
1.37
1.5
1.5
0.23
0.31
mg/l
—
10
81
5
17
2.96
1.36
1.0
1.1
—
—
—
0
0
17
98
1.76
1.32
1.1
1.1
—
—
—
0
0
13
230
0.55
1.30
1.8
1.9
3.65
3.48
mmol/l
—
8
175
193
2161
0.83
1.29
6.5
4.0
0.00
0.72
estimate
0.51
42
424
57
436
1.35
1.26
2.1
1.8
2.07
1.55
%
1.91
50
376
10
49
2.06
1.22
2.5
2.7
—
—
—
0
0
8
38
2.12
1.19
1.1
1.2
—
—
—
0
0
165
1449
1.21
1.18
6.2
3.5
2.31
2.35
mmol/l
1.97
152
1299
5
21
2.39
1.09
1.2
1.1
—
—
—
0
0
193
2136
0.84
1.08
6.3
4.0
23.69
3.60
estimate
0.39
48
451
7
32
2.20
1.08
1.1
1.2
90.71
95.69
pmol/l
—
7
32
271
2505
1.18
1.06
20.0
5.5
7.55
6.77
mmol/l
5.56
266
2385
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
22
2.29
1.03
1.2
1.2
—
—
—
0
0
7
34
2.07
1.03
1.0
1.1
—
—
—
0
0
142
1607
0.84
1.02
6.0
3.9
0.07
0.01
estimate
0.55
42
377
7
35
2.01
1.00
1.6
1.2
—
—
—
0
0
13
76
1.73
0.99
1.6
1.2
147.58
31.25
u/l
0.44
13
65
13
76
1.73
0.99
9.3
3.3
12.26
8.74
pmol/l
0.54
13
76
93
784
1.23
0.99
4.7
3.2
1.71
0.98
e6/l
0.67
55
434
9
49
1.85
0.99
6.3
3.3
13.44
12.28
index
—
9
32
130
1139
1.19
0.94
6.8
2.9
361.74
358.87
umol/l
0.10
110
994
18
118
1.55
0.92
1.4
1.3
—
—
—
0
0
22
151
1.48
0.92
1.1
1.3
—
—
—
0
0
6
29
2.08
0.89
1.2
1.1
—
—
—
0
0
6
31
1.95
0.84
1.2
1.2
—
—
—
0
0
6
31
1.95
0.84
1.2
1.1
—
—
—
0
0
6
31
1.95
0.84
1.2
1.1
—
—
—
0
0
15
98
1.55
0.79
1.1
1.1
—
—
—
0
0
104
908
1.18
0.79
1.8
1.8
551.38
5284447.43
pmol/l
0.50
84
757
6
34
1.77
0.76
1.2
1.1
—
—
—
0
0
43
345
1.27
0.73
4.0
2.8
60.70
65.89
ml/min/173m2
0.27
23
150
202
2178
0.88
0.73
3.3
2.8
—
—
—
0
0
9
59
1.53
0.68
10.7
2.0
12.44
10.56
mmol/l
—
9
59
7
43
1.64
0.67
1.1
1.1
—
—
—
0
0
285
2995
0.89
0.65
7.7
4.2
22.34
12.71
mm/h
9.61
276
2762
5
29
1.73
0.64
2.8
1.6
62.00
84.55
umol/l
—
5
29
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
109
1204
0.88
0.56
6.1
3.9
0.00
0.01
estimate
0.78
44
405
84
744
1.16
0.55
5.3
3.3
1.78
1.70
e6/l
0.05
45
397
9
136
0.66
0.52
2.4
1.9
25.67
41.68
nmol/l
—
9
127
6
40
1.51
0.51
1.2
1.1
—
—
—
0
0
6
40
1.51
0.51
1.5
1.5
29.82
27.56
u/l
—
6
35
105
1155
0.88
0.51
5.5
3.4
0.00
0.08
estimate
0.60
40
350
33
399
0.81
0.50
1.2
1.5
—
—
—
0
0
116
1060
1.12
0.49
5.1
2.6
—
—
—
0
0
27
217
1.26
0.49
1.2
1.2
28.04
133.99
u/ml
—
8
85
189
1776
1.10
0.48
3.6
2.4
72.40
77.39
nmol/l
1.94
175
1561
93
843
1.13
0.45
1.3
1.2
2.81
1.31
u/ml
0.55
28
235
6
91
0.66
0.42
1.3
3.6
3617.32
478.98
u/ml
—
6
83
5
32
1.57
0.42
1.6
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
9.24
—
0
17
0
17
0.00
0.40
0.0
2.5
—
42.05
—
0
17
8
112
0.71
0.37
1.0
1.1
1.47
1.55
g/l
—
8
112
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
194
1853
1.08
0.33
5.8
3.0
325.41
138.35
ug/l
2.90
182
1714
49
546
0.89
0.31
1.4
1.5
—
—
—
0
0
124
1315
0.92
0.30
2.0
1.8
17.73
20.40
nmol/l
1.56
112
1092
7
57
1.23
0.29
1.9
1.6
—
—
—
0
0
9
118
0.76
0.27
1.0
1.1
0.97
0.89
g/l
—
9
118
184
1913
0.94
0.26
2.6
2.2
92.80
94.35
pmol/l
0.22
115
1036
0
11
0.00
0.21
0.0
2.2
—
2.37
—
0
6
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
6
50
1.20
0.19
1.2
1.1
—
1.32
—
0
9
23
259
0.88
0.19
2.0
1.8
—
—
—
0
0
26
284
0.91
0.14
2.1
1.9
—
—
—
0
0
178
1740
1.04
0.12
6.8
4.1
79.60
47.60
ng/l
0.49
155
1313
5
44
1.14
0.10
1.4
1.3
—
—
—
0
0
143
1461
0.97
0.09
5.4
4.0
28.60
9.97
mg/mmol
1.23
102
923
12
134
0.89
0.09
1.6
1.8
3.06
4.29
mg/l
0.30
12
104
12
107
1.12
0.08
1.4
1.3
—
—
—
0
0
16
174
0.92
0.07
1.2
1.0
—
—
—
0
0
9
100
0.90
0.06
1.3
1.7
—
—
—
0
0
311
3134
0.98
0.06
17.5
8.4
89.53
79.98
u/l
2.77
304
2945
196
1937
1.02
0.06
5.3
2.9
—
—
estimate
—
0
0
46
476
0.96
0.06
16.1
7.4
—
—
—
0
0
148
1468
1.01
0.02
4.4
3.3
6.70
7.78
mmol/l
2.61
130
1215
10
104
0.96
0.00
1.8
1.9
—
—
—
0
0
13
126
1.03
0.00
1.6
2.0
—
—
—
0
0
48
485
0.99
0.00
2.7
4.4
4.81
39.26
ug/l
1.30
42
402
88
876
1.01
0.00
3.1
3.1
2.49
2.45
mmol/l
1.56
79
784
92
924
0.99
0.00
6.2
4.2
15.27
1.02
kg/l
0.49
71
627
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
21.33
—
0
9
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.43
—
0
5
8
79
1.01
-0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
85.67
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_ARDS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_ARDS | 4.114 [2.99, 5.67] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.123 |
During the follow-up period (1.1.1998 — 31.12.2019), 380 out of 840 females with J10_ARDS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_ARDS | 3.869 [3.11, 4.82] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.02 |
During the follow-up period (1.1.1998 — 31.12.2019), 581 out of 1115 males with J10_ARDS died.
Mortality risk
Mortality risk for people of age
years, who have J10_ARDS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.343% | 0.847% |
| 5 | 2.574% | 4.935% |
| 10 | 6.118% | 11.15% |
| 15 | 11.445% | 19.998% |
| 20 | 18.726% | 31.948% |
Relationships between endpoints
↥Index endpoint: J10_ARDS – Adult respiratory distress syndrome
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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