synovitis: ['Inflammation of the SYNOVIAL MEMBRANE [ MeSH ]']
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
350 |
4. Check minimum number of eventsNone |
350 |
5. Include endpointsNone |
350 |
6. Filter based on genotype QC (FinnGen only) |
323 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M67
- Name in latin
- Synovitis transitoria
Similar endpoints
↥List of similar endpoints to
Transient synovitis
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4739 | 1722 | 3013 |
| Only index persons | 3886 | 1464 | 2422 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.05 | 0.08 |
| Only index persons | 0.08 | 0.05 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 6.89 | 8.17 | 6.11 |
| Only index persons | 8.02 | 10.50 | 6.51 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 323 | 190 | 133 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.06 |
| Median age at first event (years) | 23.63 | 31.13 | 12.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 336
- Matched controls
- 3360
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M67.3
ICD-10 Finland
Transient synovitis
+∞
307.7
336
*
M25.5
ICD-10 Finland
Pain in joint
4.6
42.4
162
563
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
17.9
40.6
34
21
M67.4
ICD-10 Finland
Ganglion
11.1
40.1
45
46
M13.9
ICD-10 Finland
Arthritis, unspecified
7.5
32.9
51
78
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
7.4
26.1
40
60
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
246.1
22.9
23
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
5.0
22.2
53
122
M79.6
ICD-10 Finland
Pain in limb
3.1
21.7
143
654
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
7.7
19.4
28
39
A07EC01
ATC
sulfasalazine; oral, rectal
6.1
19.1
35
63
M65.3
ICD-10 Finland
Trigger finger
18.5
19.1
29
17
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.7
18.9
68
213
L04AX03
ATC
methotrexate; systemic
4.5
18.6
49
122
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
5.3
18.3
39
81
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
55.8
18.2
21
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
6.0
17.8
33
60
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
8.0
17.2
24
32
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
6.4
16.3
28
47
N06AA09
ATC
amitriptyline; systemic
5.6
16.1
32
62
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
7.6
15.9
23
32
L88
ICPC
Rheumatoid/seropositive arthritis
7.4
15.5
23
33
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
6.7
14.8
24
38
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
37.9
14.6
18
5
NF1AA
NOMESCO Finland
Hip X-ray examination
5.2
14.6
31
64
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
44.5
14.2
17
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.7
13.7
47
141
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.8
13.0
43
126
P01BA02
ATC
hydroxychloroquine; oral
4.7
12.9
31
71
M02AA07
ATC
piroxicam; topical
2.6
12.9
91
415
ACC51
NOMESCO Finland
Release of median nerve
5.5
12.7
25
48
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.2
12.1
53
186
M01AH05
ATC
etoricoxib; oral
2.2
11.9
183
1168
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
10.6
11.7
22
22
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
15.8
11.4
18
12
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.2
11.4
32
83
L29
ICPC
Musculoskeletal sympt/complt other
3.5
11.0
41
130
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
10.1
10.9
21
22
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
13.5
10.8
18
14
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.1
10.5
47
167
M01AE02
ATC
naproxen; oral, rectal
2.2
10.3
212
1485
N02AJ06
ATC
codeine and paracetamol; systemic
2.1
10.1
134
793
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
41.4
10.0
12
*
N02AX02
ATC
tramadol; systemic, rectal
2.2
10.0
108
588
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.4
10.0
38
122
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
9.9
81
391
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
3.6
9.9
34
102
N06AX21
ATC
duloxetine; oral
3.2
9.9
41
139
M54.5
ICD-10 Finland
Low back pain
2.2
9.9
114
638
J01FF01
ATC
clindamycin; systemic
2.4
9.8
82
400
SPAT1263
SPAT
Sampling
2.1
9.8
154
969
M01AH01
ATC
celecoxib; oral
3.0
9.6
45
164
N03AX12
ATC
[U] gabapentin; oral
3.1
9.6
42
147
L15
ICPC
Knee symptom/complaint
2.2
9.3
94
496
SPAT1153
SPAT
Removal of sutures
2.3
9.1
87
449
M01AC06
ATC
meloxicam; systemic, rectal
2.2
8.9
88
459
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
12.0
8.7
15
13
R01BA52
ATC
pseudoephedrine, combinations; oral
2.3
8.6
77
385
SPAT1255
SPAT
Intravenous administration of medicine
4.3
8.4
22
54
L04AA13
ATC
[U] leflunomide
11.2
8.4
15
14
SPAT1229
SPAT
Assessment of need for aid
4.4
8.3
21
50
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
3.2
8.3
33
109
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
8.5
8.2
17
21
N03AX16
ATC
[U] pregabalin
2.5
8.0
53
231
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.0
7.9
37
134
L17
ICPC
Foot/toe symptom/complaint
2.0
7.6
106
627
L01BA01
ATC
methotrexate; systemic
7.9
7.5
16
21
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.0
7.5
33
116
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
13.8
7.4
12
9
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
3.5
7.4
26
79
M23.8
ICD-10 Finland
Other internal derangements of knee
4.5
7.3
18
42
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.4
7.3
26
80
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.1
7.3
20
51
ZXA00
NOMESCO Finland
Right side
2.2
7.3
65
324
M02AA10
ATC
ketoprofen; topical
2.7
7.2
41
165
H02AB06
ATC
prednisolone; systemic
1.9
7.2
130
838
ZXA05
NOMESCO Finland
Left side
2.3
7.0
57
273
M17.5
ICD-10 Finland
Other secondary gonarthrosis
14.2
6.9
11
8
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
11.3
6.8
12
11
L16
ICPC
Ankle symptom/complaint
2.4
6.8
53
248
N02BE01
ATC
paracetamol; systemic, rectal
2.1
6.7
274
2271
S83.2
ICD-10 Finland
Tear of meniscus, current
3.3
6.7
25
79
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
6.6
121
779
X58
ICD-10 Finland
Exposure to other specified factors
2.2
6.5
62
316
B01AB05
ATC
enoxaparin; parenteral
2.1
6.4
73
399
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
+∞
6.3
6
*
NGF10
NOMESCO Finland
Total synovectomy of knee, open
+∞
6.3
6
*
G56.2
ICD-10 Finland
Lesion of ulnar nerve
6.5
6.2
15
24
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.2
69
373
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
6.2
77
435
M01AB05
ATC
diclofenac; systemic, rectal
1.8
6.1
171
1242
L04AB01
ATC
etanercept; parenteral
8.8
6.1
12
14
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
6.9
6.1
14
21
M16.1
ICD-10 Finland
Other primary coxarthrosis
3.0
6.1
27
95
ZXD20
NOMESCO Finland
Day surgery
2.4
6.1
43
193
Z50.1
ICD-10 Finland
Other physical therapy
4.0
6.1
17
44
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
6.0
156
1107
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
6.0
124
823
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
80
371
2.52
10.77
1.4
1.2
12.90
15.37
u/ml
0.08
31
138
198
1364
2.10
9.89
5.3
3.3
0.00
0.00
estimate
-0.00
41
273
196
1354
2.07
9.61
4.9
3.3
0.00
0.00
estimate
0.50
40
279
198
1373
2.08
9.61
5.3
3.4
0.00
0.00
estimate
-0.00
40
260
22
32
7.28
9.48
2.1
1.3
—
—
—
0
0
211
1560
1.95
7.84
15.2
9.9
3.76
3.96
e9/l
0.61
195
1318
154
1028
1.92
7.79
4.4
3.2
0.00
0.02
estimate
0.88
33
235
242
1878
2.03
7.78
8.7
7.0
82.42
83.46
u/l
0.10
233
1777
194
1405
1.90
7.57
8.3
5.8
6.50
6.33
mmol/l
0.42
182
1306
109
670
1.93
6.90
5.7
3.3
1.02
1.02
kg/l
0.22
78
431
77
420
2.08
6.82
1.4
1.2
30.92
33.01
iu/ml
0.07
19
117
116
769
1.78
5.58
3.1
2.7
0.00
0.02
estimate
0.99
30
224
36
160
2.40
5.20
2.6
2.2
23.03
11.75
au/ml
—
7
13
108
721
1.73
4.98
5.3
3.4
0.00
0.01
estimate
0.80
37
260
120
834
1.68
4.74
6.8
3.2
—
—
—
0
0
82
512
1.80
4.74
3.2
1.8
0.96
1.34
mg/l
0.76
66
380
14
31
4.67
4.61
2.5
1.4
—
—
—
0
0
149
1119
1.60
4.21
3.3
2.8
—
—
estimate
—
0
0
104
720
1.64
4.07
2.9
3.0
14.80
27.87
ng/l
2.03
61
410
11
22
5.13
4.04
9.6
2.4
10.45
12.36
%
0.30
11
22
131
962
1.59
4.02
7.9
5.2
36.87
37.18
g/l
0.27
126
918
181
1436
1.56
3.95
4.0
3.0
97.57
87.40
ug/l
0.26
175
1361
35
176
2.10
3.80
1.7
1.6
—
—
—
0
0
147
1120
1.56
3.80
3.1
2.6
76.03
72.37
nmol/l
0.81
142
1041
305
2777
2.07
3.73
20.4
11.3
22.77
22.44
mg/l
0.06
248
2133
57
343
1.80
3.68
2.4
1.9
—
—
—
0
0
19
74
2.66
3.62
5.5
10.1
1.65
1.55
%
0.33
19
68
260
2267
1.65
3.60
6.2
4.7
37.30
37.38
mmol/mol
0.05
253
2151
32
159
2.12
3.59
3.1
1.7
—
—
—
0
0
77
509
1.67
3.56
4.2
2.8
301.40
329.97
umol/l
2.10
70
468
10
22
4.65
3.45
10.5
2.4
—
—
—
0
0
17
66
2.66
3.26
2.5
2.1
—
—
—
0
0
16
61
2.70
3.18
2.5
1.9
—
—
—
0
0
144
1132
1.48
3.03
13.6
8.7
1.22
1.22
mmol/l
0.63
128
998
37
211
1.85
2.85
8.7
12.7
0.48
0.71
mmol/l
0.22
30
176
5
6
8.43
2.76
1.6
1.2
—
—
—
0
0
5
6
8.43
2.76
1.6
1.0
—
—
—
0
0
17
73
2.40
2.70
1.6
1.4
1.18
1.21
g/l
0.13
17
68
310
2896
1.91
2.63
15.4
9.3
26.28
26.51
u/l
0.08
305
2818
10
30
3.40
2.62
3.0
1.8
—
—
—
0
0
7
15
4.74
2.61
1.0
1.0
—
—
—
0
0
115
895
1.43
2.45
1.6
1.8
95.57
94.63
pmol/l
0.09
67
478
255
2286
1.48
2.43
3.9
3.6
—
—
—
0
0
20
97
2.13
2.42
1.5
1.5
0.01
0.03
iu/ml
—
5
15
245
2180
1.46
2.42
4.8
3.9
14.41
14.64
pmol/l
0.90
231
1982
27
148
1.90
2.36
1.4
2.0
—
—
—
0
0
9
28
3.27
2.32
1.3
2.1
—
—
—
0
0
81
596
1.47
2.30
5.0
4.1
13.68
10.36
mg/mmol
0.25
55
386
128
1027
1.40
2.26
16.2
8.6
1.22
1.22
mmol/l
0.03
123
957
57
392
1.55
2.22
2.4
2.2
—
—
—
0
0
21
108
2.01
2.20
2.0
1.5
3.40
4.55
iu/ml
—
7
22
89
674
1.44
2.17
6.1
2.9
0.07
0.33
e6/l
3.77
66
460
40
254
1.65
2.16
2.6
1.8
—
—
—
0
0
35
216
1.69
2.10
6.4
5.6
—
—
—
0
0
10
37
2.75
2.08
2.8
2.2
—
—
—
0
0
13
56
2.37
2.07
1.5
1.7
—
—
—
0
0
6
15
4.05
2.04
3.5
5.5
1233.67
1069.67
mg
—
6
15
308
2906
1.72
2.03
20.9
13.2
70.51
71.10
umol/l
0.13
308
2867
9
32
2.86
2.01
1.2
1.4
—
—
—
0
0
16
77
2.13
2.00
1.4
2.0
—
—
—
0
0
287
2668
1.52
1.97
20.9
12.6
139.08
139.62
mmol/l
3.56
287
2606
5
11
4.60
1.95
1.6
1.3
—
—
—
0
0
5
11
4.60
1.95
1.8
1.4
—
—
—
0
0
287
2670
1.51
1.94
21.0
12.7
3.95
3.92
mmol/l
0.88
287
2598
56
397
1.49
1.90
3.5
2.8
2165.00
557.91
ng/l
0.46
37
264
27
161
1.74
1.85
1.9
2.8
79.80
73.17
ml/min/173m2
—
10
69
14
66
2.17
1.84
7.1
2.6
13.12
3.15
index
—
9
41
5
12
4.21
1.83
1.2
1.3
144.98
115.21
iu/ml
—
5
12
5
12
4.21
1.83
1.6
1.3
—
—
—
0
0
105
841
1.36
1.82
1.7
1.5
1.68
1.94
u/ml
0.13
35
227
7
23
3.09
1.81
1.4
2.3
—
—
—
0
0
214
1908
1.33
1.76
3.7
3.1
40.24
37.52
u/l
0.21
206
1829
22
125
1.81
1.76
1.7
1.5
—
—
—
0
0
32
203
1.64
1.76
2.3
2.4
11553.30
3640.45
u/l
—
6
82
8
30
2.71
1.73
3.1
1.7
—
—
—
0
0
7
24
2.96
1.73
1.1
1.3
10.71
11.00
mm/h
—
7
24
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
13
3.89
1.72
1.0
1.1
91.80
109.92
%
—
5
13
61
451
1.43
1.68
2.5
2.4
—
—
—
0
0
6
19
3.20
1.67
1.8
2.6
439.17
830.16
u/ml
—
6
19
326
3150
2.17
1.67
29.1
17.2
261.03
258.16
e9/l
0.38
320
3074
10
42
2.42
1.63
1.4
1.6
—
—
—
0
0
58
429
1.43
1.60
6.2
2.7
0.67
0.81
e6/l
0.33
34
213
326
3154
2.13
1.59
29.0
17.1
4.55
4.59
e12/l
0.77
320
3072
6
20
3.04
1.59
15.8
2.5
32.17
26.70
%
—
6
20
27
172
1.62
1.48
5.9
4.8
61.19
66.02
ng/l
0.22
27
161
45
324
1.45
1.44
2.9
2.4
2.46
2.40
g/l
0.29
45
296
75
591
1.35
1.42
3.1
2.2
—
—
—
0
0
12
60
2.04
1.40
1.8
1.4
—
—
—
0
0
5
17
2.97
1.36
2.4
3.8
2.76
2.48
nmol/l
—
5
17
35
243
1.49
1.34
2.9
1.9
—
—
—
0
0
261
2436
1.32
1.31
12.8
10.2
93.88
93.45
ml/min/173m2
0.11
236
2146
9
43
2.12
1.31
3.2
1.7
—
—
—
0
0
5
18
2.80
1.29
1.2
1.2
—
—
—
0
0
11
55
2.03
1.29
23.4
7.0
75.24
66.34
%
1.19
11
55
81
657
1.31
1.26
3.1
2.2
2.52
2.61
mg/l
0.18
75
553
30
205
1.51
1.25
13.2
8.6
1.65
1.08
mmol/l
0.95
23
152
6
25
2.42
1.25
1.0
1.2
—
—
—
0
0
31
214
1.49
1.23
6.9
4.9
240.13
256.26
u/l
0.40
31
207
8
37
2.19
1.22
2.0
1.4
—
—
—
0
0
53
407
1.36
1.19
1.6
1.7
399.67
43132298.37
pmol/l
0.69
48
364
33
234
1.45
1.16
1.1
1.3
48.82
139.56
u/ml
2.28
16
103
7
31
2.28
1.11
2.4
2.5
18.60
16.76
%
—
7
31
14
81
1.76
1.10
3.2
9.3
23.84
24.35
mmol/l
0.23
14
81
20
129
1.59
1.08
10.2
14.2
93.75
94.49
%
0.19
20
129
271
2566
1.29
1.06
27.0
14.7
334.95
333.92
g/l
1.22
271
2546
45
344
1.36
1.05
5.3
2.3
27.90
29.30
s
1.60
45
334
40
301
1.37
1.03
14.8
8.0
103.90
104.95
mmol/l
1.02
40
301
50
390
1.33
1.03
6.4
2.8
1.61
2.67
e6/l
0.78
26
178
37
275
1.39
1.03
20.9
5.2
5.23
4.81
kpa
0.45
37
267
251
2365
1.24
0.96
4.5
3.4
1.24
1.21
mmol/l
0.25
246
2232
22
151
1.49
0.93
16.0
9.8
8.85
9.28
kpa
0.51
22
146
9
52
1.75
0.93
2.8
2.3
—
—
—
0
0
106
921
1.22
0.92
1.9
1.8
—
—
—
0
0
12
71
1.72
0.90
1.3
1.3
—
—
—
0
0
6
30
2.02
0.87
1.0
2.0
—
—
—
0
0
37
284
1.34
0.86
1.5
1.6
1113.23
1163.39
nmol/l
0.09
31
223
16
104
1.57
0.86
1.2
1.3
—
—
—
0
0
31
232
1.37
0.85
28.4
13.2
25.09
24.98
mmol/l
0.08
31
232
8
47
1.72
0.81
1.4
1.4
—
—
—
0
0
19
132
1.47
0.78
1.6
1.4
—
—
—
0
0
5
24
2.10
0.75
13.0
2.1
0.60
0.83
index
—
5
24
7
42
1.68
0.69
1.7
1.2
—
—
—
0
0
7
44
1.60
0.65
1.3
1.8
—
—
—
0
0
13
88
1.50
0.61
1.5
1.4
—
—
—
0
0
68
589
1.19
0.61
1.5
1.5
16.01
19.07
nmol/l
1.43
62
507
11
72
1.55
0.60
1.4
1.8
—
—
—
0
0
26
203
1.30
0.57
2.6
2.9
—
—
—
0
0
55
470
1.20
0.57
4.6
3.4
1681.15
914.18
ng/l
0.41
48
386
20
151
1.35
0.55
3.3
4.1
1.21
1.23
mmol/l
0.44
15
130
28
226
1.26
0.50
22.2
5.5
24.41
23.85
mmol/l
0.90
28
226
249
2400
1.14
0.48
4.8
3.8
5.71
5.66
mmol/l
0.29
239
2228
14
103
1.37
0.46
2.1
1.7
202.25
203.42
u/ml
—
8
54
259
2508
1.14
0.44
5.0
4.0
1.45
1.46
mmol/l
0.22
253
2376
8
56
1.44
0.43
1.1
1.4
—
—
—
0
0
5
32
1.57
0.42
1.2
1.2
0.50
0.48
e9/l
—
5
32
5
33
1.52
0.41
2.4
1.4
13.16
12.85
%
—
5
33
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
26
214
1.23
0.41
1.0
1.1
—
—
—
0
0
26
214
1.23
0.41
1.4
1.3
—
—
—
0
0
12
88
1.38
0.40
1.7
1.8
—
—
—
0
0
88
807
1.12
0.38
3.2
3.3
2.35
2.37
mmol/l
0.49
82
757
16
125
1.29
0.37
2.1
1.7
—
—
—
0
0
54
481
1.15
0.37
1.5
1.5
—
—
—
0
0
21
172
1.24
0.35
1.4
1.5
256.19
341.61
mu/l
1.38
21
164
26
219
1.20
0.34
21.5
10.5
1.47
1.37
mmol/l
0.16
26
213
13
100
1.31
0.34
1.6
1.5
65.99
52.31
ug/l
0.82
13
100
14
109
1.30
0.34
38.0
10.2
1.22
1.15
mg/l
0.14
14
103
10
74
1.36
0.32
1.0
1.1
—
—
—
0
0
12
92
1.32
0.32
1.3
1.3
—
—
—
0
0
41
364
1.14
0.30
4.6
4.2
22.62
21.61
%
0.19
20
168
9
73
1.24
0.25
1.0
1.1
—
—
—
0
0
11
136
0.80
0.23
1.1
1.6
2.48
2.64
mg/l
—
6
98
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
24
272
0.87
0.21
2.8
3.0
0.75
0.77
ug/l
0.04
16
170
0
10
0.00
0.21
0.0
3.9
—
132.90
—
0
10
0
10
0.00
0.21
0.0
1.4
—
10.00
—
0
5
107
1021
1.07
0.21
2.0
1.8
1.33
1.30
mmol/l
0.15
96
893
35
385
0.90
0.20
1.5
1.7
3.47
3.42
ratio
0.08
21
290
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
50
1.20
0.20
1.3
1.1
—
—
—
0
0
72
684
1.07
0.16
2.8
2.3
—
—
—
0
0
13
111
1.18
0.16
1.8
1.7
—
—
—
0
0
15
133
1.13
0.12
26.3
4.7
0.59
0.61
%
0.08
15
133
11
96
1.15
0.10
1.3
1.6
—
—
—
0
0
14
125
1.13
0.10
1.5
1.5
1.05
1.17
ratio
—
8
77
14
125
1.13
0.10
1.5
1.5
0.91
1.14
ratio
—
8
77
14
125
1.13
0.10
1.5
1.5
0.95
0.96
ratio
—
8
77
76
734
1.05
0.10
2.9
2.4
—
—
—
0
0
5
60
0.83
0.08
1.8
2.0
4.16
4.52
g/l
—
5
55
5
60
0.83
0.08
1.8
2.0
7.00
7.20
g/l
—
5
55
5
60
0.83
0.08
1.8
2.0
3.82
3.49
g/l
—
5
55
5
62
0.80
0.08
2.0
1.7
—
—
—
0
0
7
64
1.10
0.08
1.1
1.4
2.55
4.00
ug/l
—
7
59
7
67
1.05
0.08
1.0
1.2
—
8.59
—
0
15
7
67
1.05
0.08
1.9
1.4
—
—
—
0
0
11
121
0.91
0.06
1.5
1.5
—
—
—
0
0
30
288
1.05
0.04
1.3
1.5
3.55
3.35
mmol/l
0.41
15
200
12
111
1.08
0.04
1.1
1.1
1.13
1.82
u/ml
—
7
69
24
234
1.03
0.00
3.5
2.9
0.22
0.22
g/l
0.10
24
220
12
122
0.98
0.00
1.6
1.3
—
—
—
0
0
17
167
1.02
0.00
1.6
1.4
—
—
—
0
0
12
125
0.96
0.00
1.1
1.2
0.35
3.79
u/ml
—
7
77
11
114
0.96
0.00
2.5
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
24
240
1.00
-0.00
3.8
3.7
33.89
31.28
%
0.55
18
165
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
54
0.92
-0.00
1.0
1.2
—
50.13
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
12.88
—
0
5
5
50
1.00
-0.00
1.2
1.3
—
1.04
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
76.44
—
0
9
Mortality – FinRegistry
↥Association
Association between endpoint M13_TRANSSYNOVITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_TRANSSYNOVITIS | 1.188 [0.89, 1.59] | 0.244 |
| Birth year | 0.993 [0.98, 1.0] | 0.098 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 1551 females with M13_TRANSSYNOVITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_TRANSSYNOVITIS | 1.195 [0.91, 1.56] | 0.196 |
| Birth year | 0.989 [0.98, 1.0] | 0.024 |
During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 2694 males with M13_TRANSSYNOVITIS died.
Mortality risk
Mortality risk for people of age
years, who have M13_TRANSSYNOVITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.247% |
| 5 | 0.579% | 1.482% |
| 10 | 1.456% | 3.667% |
| 15 | 2.989% | 7.022% |
| 20 | 5.127% | 11.837% |
Relationships between endpoints
↥Index endpoint: M13_TRANSSYNOVITIS – Transient synovitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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