Other and unspecified heterotropia

H7_HETEROTRONAS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H50.4 Cause of death: ICD-10 — H50.4 2 out of 7 registries used, show all original rules.	122
4. Check minimum number of events None	122
5. Include endpoints None	122
6. Filter based on genotype QC (FinnGen only)	107

Control definitions (FinnGen only)

Control exclude: H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H50
Name in latin: Heterotropia alia sive non specificata

NAME	H7_HETEROTRONAS
CONTROL_EXCLUDE	H7_OCUMUSCLE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H504
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H504
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other and unspecified heterotropia based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	971	511	459
Only index persons	817	435	382
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.02	0.02	0.01
Median age at first event (years)
Whole population	24.32	23.48	25.22
Only index persons	34.01	31.14	37.28

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	107	65	42
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	55.02	52.84	58.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
112: Matched controls
1120

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H50.4

ICD-10 Finland

Other and unspecified heterotropia

+∞

161.6

112

H53.2

ICD-10 Finland

Diplopia

122.5

38.9

H50.2

ICD-10 Finland

Vertical strabismus

+∞

36.5

XCW99

NOMESCO Finland

Other investigative procedure of eye

12.7

33.6

CEC10

NOMESCO Finland

Recession and resection of extraocular muscle

+∞

18.2

CEC00

NOMESCO Finland

Recession of extraocular muscle

+∞

16.0

H49.1

ICD-10 Finland

Fourth [trochlear] nerve palsy

+∞

14.9

H50.0

ICD-10 Finland

Convergent concomitant strabismus

+∞

13.8

H50.1

ICD-10 Finland

Divergent concomitant strabismus

+∞

12.7

WX408

NOMESCO Finland

General anesthesy, balanced

3.9

11.0

181

Z01.0

ICD-10 Finland

Examination of eyes and vision

4.1

10.3

121

XCK00

NOMESCO Finland

Perimetry

9.5

9.9

WX002

NOMESCO Finland

Sedation and analgesia

4.2

9.9

102

CEC60

NOMESCO Finland

Transposition of extraocular muscle with adjustable suture

+∞

9.5

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

5.0

9.1

H50.30

ICD-10 Finland

Intermittent esotropy

+∞

8.4

ZXE10

NOMESCO Finland

More than one and less than three hours

3.0

7.5

250

CEC85

NOMESCO Finland

Combined correction of cyclodeviation

+∞

7.4

CEW99

NOMESCO Finland

Other operation on extraocular muscle

+∞

7.4

H50.31

ICD-10 Finland

Intermittent exotropia

+∞

6.3

WX100

NOMESCO Finland

Conjunctival surface anesthesia

3.5

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

166

2.84

5.84

3.6

3.0

0.72

0.81

e6/l

0.11

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

159

2.75

5.35

3.7

3.1

3.29

3.20

e6/l

0.02

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

346

2.40

4.94

4.2

3.2

—

(3019309) Folate [Moles/volume] in Red Blood Cells

138

2.72

4.89

1.4

1.6

1159.83

1181.55

nmol/l

0.04

110

(3002582) Erythrocytes [#/volume] in Urine

331

2.38

4.84

4.1

3.2

118.44

255.41

e6/l

0.28

251

(3018418) pH of Serum or Plasma

278

2.27

4.22

4.7

4.0

7.40

0.07

193

(3030467) Casts [#/volume] in Urine by Automated count

289

2.24

4.10

4.0

2.9

0.28

0.41

e6/l

0.29

206

(40758558) Short blood count panel - Blood

281

2.24

4.09

5.8

7.8

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

464

2.03

3.28

12.7

9.2

1.23

1.21

mmol/l

1.44

395

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

3.95

3.19

1.7

1.5

0.24

0.23

g/l

0.17

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

3.95

3.19

1.9

1.6

1.17

1.22

g/l

0.14

(3013826) Glucose [Moles/volume] in Serum or Plasma

567

2.06

3.14

7.2

6.3

6.22

6.56

mmol/l

0.88

529

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

413

1.98

3.11

2.3

2.0

100.55

96.15

pmol/l

0.32

208

(3044290) Cell count panel - Cerebral spinal fluid

4.56

3.07

2.2

3.2

—

(3018095) Leukocytes [#/volume] in Urine

390

1.94

2.97

5.0

4.0

71.87

64.13

e6/l

0.06

261

(3048689) Calprotectin [Mass/mass] in Stool

133

2.24

2.96

2.7

1.8

339.00

110.29

ug/g

0.85

100

(3007164) IgA [Mass/volume] in Serum or Plasma

223

1.91

2.44

1.7

1.6

1.89

2.42

g/l

0.89

128

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

6.48

2.39

1.2

1.1

—

(3015736) pH of Urine

429

1.79

2.38

3.4

3.8

6.12

6.31

0.60

244

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.33

14.4

16.6

24.56

25.12

mmol/l

0.29

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

4.07

2.29

1.1

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

117

2.10

2.26

1.7

1.8

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.51

2.22

2.1

1.4

—

(3023410) Appearance of Cerebral spinal fluid

4.46

2.18

2.8

4.2

—

(42870588) Differential panel, method unspecified - Blood

331

1.72

2.04

5.5

7.9

—

(3019150) Specific gravity of Urine by Refractometry

236

1.77

2.00

2.9

4.1

1.02

kg/l

0.15

155

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

2.87

1.98

1.1

2.4

324.78

478.48

mg/l

—

(3023520) Reticulocytes [#/volume] in Blood

2.09

1.93

2.8

4.2

61.65

73.32

e9/l

0.89

(3035350) Ketones [Presence] in Urine by Test strip

559

1.67

1.84

4.1

0.00

estimate

-0.00

136

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

451

1.65

1.84

2.6

2.9

—

estimate

—

(3011288) Drugs identified in Urine by Screen method Nominal

2.89

1.83

1.5

1.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

242

1.72

1.81

1.3

0.83

0.69

u/ml

—

(3044640) Blood type and Crossmatch panel - Blood

304

1.67

1.80

2.2

2.5

—

(3019198) Lymphocytes [#/volume] in Blood

512

1.64

1.78

6.8

7.8

1.75

2.04

e9/l

1.05

454

(3021601) Nitrite [Presence] in Urine by Test strip

552

1.65

1.77

4.1

0.00

estimate

-0.00

133

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

2.70

1.69

1.1

1.3

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

171

1.76

1.66

1.3

1.4

1.83

15.29

u/ml

1.10

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

100

894

2.11

1.66

5.1

4.8

5.74

5.91

mmol/l

0.78

812

(3013650) Neutrophils [#/volume] in Blood by Automated count

559

1.61

1.63

9.8

11.3

4.35

4.17

e9/l

0.21

485

(3013115) Eosinophils [#/volume] in Blood

520

1.60

1.61

6.8

8.0

0.19

0.18

e9/l

0.09

452

(3009261) Glucose [Presence] in Urine by Test strip

560

1.60

4.0

4.2

0.00

estimate

-0.00

128

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

2.70

1.54

1.4

2.0

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

2.16

1.50

24.4

12.0

23.67

24.47

mmol/l

0.29

(3001604) Monocytes [#/volume] in Blood

506

1.56

1.49

6.8

7.6

0.55

0.58

e9/l

0.44

436

(3006315) Basophils [#/volume] in Blood

506

1.56

1.49

6.8

7.6

0.04

e9/l

0.30

436

(3023511) Choriogonadotropin [Units/volume] in Urine

2.60

1.48

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

121

1.79

1.43

1.5

2.1

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

3.03

1.37

1.2

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

1.37

0.0

1.8

—

(36660697) Celiac disease serology panel - Serum

1.91

1.35

1.1

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.11

1.32

1.2

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

103

954

1.99

1.32

19.8

15.8

26.53

23.55

mg/l

0.41

777

(3021589) Normoblasts [#/volume] in Blood

476

1.51

1.31

11.2

12.9

0.00

e9/l

1.29

393

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

191

1.62

1.31

2.5

3.8

26.52

349.41

ng/l

1.37

145

(3015235) Bicarbonate [Moles/volume] in Capillary blood

2.38

1.30

4.5

24.01

24.64

mmol/l

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

184

1.62

1.27

1.1

1.3

13.86

31.94

iu/ml

—

(3000991) Gas panel - Venous blood

1.82

1.25

20.1

12.1

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

2.25

1.24

1.4

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

2.25

1.24

3.4

6.3

103.38

91.97

—

(3014051) Protein [Presence] in Urine by Test strip

306

1.48

1.12

3.0

3.4

—

0.25

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

2.19

1.07

4.4

5.8

161.71

211.00

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

100

1.70

1.03

5.1

3.4

—

(3000492) Spirometry study

1.73

1.03

1.9

1.5

—

(3042936) Bacteria identified in Isolate by Culture

134

1.60

1.00

2.1

1.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

213

1.49

0.98

5.8

4.8

20.36

20.88

0.07

104

(40761511) CBC panel - Blood by Automated count

105

992

1.93

0.95

15.0

13.8

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.73

0.92

1.5

1.6

—

(40768797) Stomach Pathology biopsy report

120

1.60

0.92

1.2

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

137

1.56

0.92

9.0

8.5

1.02

1.09

mmol/l

0.59

126

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

225

1.46

0.91

2.5

—

(3002256) Pathology report gross observation

113

1.59

0.88

1.5

1.3

—

(3022145) Colonoscopy Study observation

105

1.61

0.87

1.3

—

(3016879) Cocaine [Presence] in Urine

1.84

0.86

1.4

1.5

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

900

1.58

0.86

18.4

14.8

86.75

83.51

ml/min/173m2

0.75

815

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

311

1.39

0.85

2.2

2.4

63.00

54.46

u/l

0.79

284

(3000764) Benzodiazepines [Presence] in Urine

1.72

0.80

1.4

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.79

0.0

1.3

—

(3026008) Bacteria identified in Urine by Culture

324

1.36

0.79

3.5

2.8

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.76

0.78

28.7

12.8

91.95

94.77

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

117

1.53

0.77

1.6

2.2

—

(3021901) Oxygen saturation in Capillary blood

2.23

0.77

3.4

3.3

93.76

89.64

—

(3049717) Cytology report of Urine Cyto stain

2.23

0.77

5.4

2.2

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

2.13

0.75

1.2

1.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

170

1.44

0.75

1.9

2.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.65

0.75

2.0

1.7

—

(3032080) INR in Blood by Coagulation assay

442

1.33

0.74

27.6

12.9

1.29

1.20

inr

0.53

364

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

930

1.56

0.73

5.6

2.72

2.66

mmol/l

0.32

856

(3025941) Bacteria identified in Stool by Culture

1.63

0.73

1.2

1.3

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

102

1.54

0.72

1.7

2.2

320.67

371.34

nmol/l

0.62

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.60

0.72

1.1

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.58

0.69

4.5

3.0

9.71

9.22

g/l

0.21

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

912

1.47

0.66

4.6

4.9

1.50

1.44

mmol/l

0.70

838

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

113

1.49

0.65

18.8

9.5

5.37

5.07

kpa

0.31

107

(3027801) Oxygen [Partial pressure] in Arterial blood

113

1.49

0.65

18.7

9.5

15.90

12.45

kpa

0.73

108

(3023368) Bacteria identified in Blood by Culture

276

1.33

0.65

5.2

4.1

—

(3027008) Opiates [Presence] in Urine

1.68

0.63

1.4

—

(3028300) Cannabinoids [Presence] in Urine

1.68

0.63

1.4

—

(3019977) pH of Arterial blood

114

1.47

0.63

18.8

9.4

7.41

7.40

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.61

0.0

3.1

—

16.35

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.60

0.0

1.9

—

(3009343) pH of Capillary blood

1.54

0.60

6.2

5.9

7.41

7.42

0.52

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

122

0.63

0.58

1.6

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

116

1.44

0.58

2.3

1.7

—

(40768443) Skin Pathology biopsy report

1.70

0.57

1.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

918

1.42

0.57

4.9

5.0

4.62

4.55

mmol/l

0.34

853

(3009445) Proteinase 3 Ab [Units/volume] in Serum

1.66

0.56

1.2

1.3

—

(3022313) Gas panel - Capillary blood

1.47

0.54

7.4

5.3

—

(3008898) HLA-B27 [Presence]

1.57

0.54

1.2

1.0

—

(3028626) Oxygen [Partial pressure] in Capillary blood

1.59

0.50

5.3

6.0

9.29

8.58

kpa

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.59

0.50

2.6

—

(3029937) Albumin [Presence] in Urine by Test strip

315

1.26

0.49

4.2

3.9

0.00

estimate

-0.00

125

(3016502) Oxygen saturation in Arterial blood

103

1.41

0.48

21.1

10.0

94.26

96.14

0.41

(3020961) Endomysium IgA Ab [Titer] in Serum

1.43

0.46

1.1

1.2

—

(40768804) Tissue Pathology biopsy report

377

1.23

0.44

2.5

2.0

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

160

1.30

0.42

3.1

3.0

1.14

0.75

ug/l

0.31

102

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.41

0.0

1.7

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.41

0.0

1.7

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.41

0.0

1.7

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.3

—

(3044941) Cell count panel - Synovial fluid

0.00

0.41

0.0

1.1

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.49

0.41

1.8

1.1

3.08

2.90

g/l

—

(3045716) Anion gap in Serum or Plasma by calculation

0.00

0.40

0.0

2.5

—

9.77

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.40

0.0

2.1

—

(1761868) Lipid panel - Serum or Plasma

388

0.82

0.38

3.2

—

(1002224) Polysomnography panel

1.38

0.35

1.2

1.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.36

0.33

4.7

7.8

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.34

0.33

2.9

2.5

0.10

0.18

e6/l

0.36

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

166

1.25

0.32

1.4

—

(3027944) Amphetamines [Presence] in Urine

1.40

0.32

1.3

1.4

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.34

0.31

2.3

1.4

—

(3003694) ABO and Rh group [Type] in Blood

310

1.19

0.31

1.4

1.6

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.32

0.31

1.7

1.8

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.21

0.27

2.8

2.6

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

867

1.19

0.26

4.1

4.2

1.22

1.28

mmol/l

0.38

790

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

133

1.24

0.26

1.7

2.4

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.37

0.24

1.8

1.1

4.04

4.55

g/l

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.37

0.24

1.8

1.1

3.58

3.61

g/l

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.37

0.24

1.8

1.1

7.08

7.46

g/l

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

229

0.85

0.22

2.5

2.3

1.33

1.53

mg/l

0.16

191

(3021788) Differential panel - Synovial fluid

0.00

0.21

0.0

1.2

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.21

0.0

3.9

—

0.82

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.21

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

0.21

0.0

5.6

—

53.73

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.21

0.0

1.4

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.21

0.0

1.1

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.9

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.8

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.20

0.0

1.7

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.20

0.0

1.7

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.1

—

1.46

—

(3041096) Erythrocytes [Presence] in Urine by Automated

319

0.88

0.20

4.0

3.6

0.00

estimate

—

104

(4035726) Immunohistochemistry procedure

1.26

0.19

1.3

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

147

1.18

0.19

1.9

2.5

—

(3012516) Albumin [Mass/volume] in Urine

292

1.13

0.19

4.2

3.5

26.69

81.35

mg/l

1.56

207

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

422

1.11

0.17

3.8

4.0

0.00

estimate

—

105

(3000494) Fungus identified in Specimen by Culture

115

0.86

0.11

1.5

—

(3012544) pH of Venous blood

115

1.15

0.11

3.4

8.1

7.38

7.39

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.12

0.10

1.2

2.0

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.07

0.09

1.2

1.3

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.06

0.08

3.5

5.8

0.92

1.02

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.06

0.08

3.5

5.8

0.68

0.62

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

363

1.07

0.08

3.0

4.0

16.72

38.03

ng/l

1.84

264

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

403

1.07

0.08

2.0

1.9

1.39

mmol/l

0.01

325

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.84

0.07

1.3

2.2

—

(40761536) Microorganisms panel - Urine sediment

1.14

0.07

6.0

3.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

220

1.06

0.04

2.5

2.1

—

(40760892) CBC W Ordered Manual Differential panel - Blood

250

1.05

0.04

4.8

5.8

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.10

0.03

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

142

1.07

0.02

1.6

2.0

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

218

1.01

0.00

1.5

1.7

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

107

1.03

0.00

4.3

5.4

264.09

263.10

u/l

0.01

102

(3020682) Albumin/Creatinine [Ratio] in Urine

303

0.99

0.00

5.0

4.0

4.23

15.02

mg/mmol

1.84

201

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

646

1.01

0.00

3.6

3.2

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3013727) Leukocytes other/Leukocytes in Blood

0.00

0.0

6.0

—

50.67

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.3

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.3

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.3

—

(3045462) Protein/Creatinine [Ratio] in Urine

0.00

0.0

1.0

—

31.33

—

(3035509) Tobramycin [Mass/volume] in Serum or Plasma

0.00

0.0

3.2

—

3.80

—

(3030558) Cytomegalovirus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

0.0

1.5

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.7

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

2.3

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

0.0

1.0

—

136.33

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.0

1.5

—

(3037534) Parathyrin related protein [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

73.08

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(4211845) Urine protein measurement

0.00

0.0

1.3

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

103.65

—

(21494814) CD8 cells/Lymphocytes in Specimen

0.00

-0.00

0.0

1.6

—

33.40

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

2.4

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(3017704) Immunofixation for Urine

0.00

-0.00

0.0

1.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.0

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.89

-0.00

1.3

2.1

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

1.4

—

4.57

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

0.00

-0.00

0.0

1.0

—

21.58

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

5.0

—

55.20

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(3032567) Hepatitis B virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3020650) Glucose [Presence] in Urine

0.00

-0.00

0.0

1.4

—

0.00

—

(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3002619) Bacteria identified in Specimen by Culture

0.00

-0.00

0.0

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

180

1.00

-0.00

2.1

1.8

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.6

—

(4024509) Urine culture

0.98

-0.00

2.8

1.9

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

1.4

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

1.4

—

10.44

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

5.0

—

4.36

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.4

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.3

—

(44806420) Estimation of glomerular filtration rate

0.00

-0.00

0.0

1.9

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.1

—

(3015183) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells

0.00

-0.00

0.0

1.1

—

10.56

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

3.2

—

91.52

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_HETEROTRONAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_HETEROTRONAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_HETEROTRONAS – Other and unspecified heterotropia

GWS hits: 1

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other and unspecified heterotropia

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints