No definition available.
Familial benign pemphigus (Hailey-Hailey disease)
Q17_FAMILIAL_BENIGN_PEMPHIGUS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
89 |
4. Check minimum number of eventsNone |
89 |
5. Include endpointsNone |
89 |
6. Filter based on genotype QC (FinnGen only) |
80 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Familial benign pemphigus (Hailey-Hailey disease)
based on the number of shared cases.
Similar with more cases:
- Other congenital malformations of skin
- Other congenital malformations of skin, including avohilmo
- Other congenital malformations
- Other congenital malformations, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 80 | 48 | 32 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 53.42 | 51.82 | 55.81 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 84
- Matched controls
- 840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q82.80
ICD-10 Finland
Benign familial pemphigus [Hailey-Hailey]
+∞
120.9
84
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
28.2
56.1
53
48
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
13.3
27.8
33
39
Q82.88
ICD-10 Finland
Other specified congenital malformations of skin
+∞
26.4
24
*
D07CC01
ATC
betamethasone and antibiotics; topical
10.9
26.2
39
62
D05BB02
ATC
acitretin; oral
30.6
19.7
26
12
D07BA04
ATC
hydrocortisone and antiseptics; topical
9.8
17.5
24
33
E0000UV, ,
ATC
6.6
14.9
62
251
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.6
13.1
35
95
D06AX01
ATC
fusidic acid; topical
6.7
11.3
21
40
Q82.81
ICD-10 Finland
Keratosis follicularis [Darier-White]
125.0
10.7
11
*
D07AD01
ATC
clobetasol; topical
5.2
10.6
28
74
E000002, ,
ATC
5.9
9.9
21
45
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
25.2
9.7
13
6
WX402
NOMESCO Finland
General anaesthesia
4.5
9.6
32
101
D07BC01
ATC
betamethasone and antiseptics; topical
5.5
9.5
22
51
D07AC13
ATC
mometasone; topical
4.0
8.9
40
156
E000001, ,
ATC
4.3
8.8
31
101
D07AC01
ATC
betamethasone; topical
3.6
7.9
47
217
Q82.82
ICD-10 Finland
Inherited keratosis palmaris et plantaris
+∞
7.4
7
*
Q82.8
ICD-10 Finland
Other specified congenital malformations of skin
+∞
7.4
7
*
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
3.6
7.2
33
128
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
10.0
6.8
13
15
WX704
NOMESCO Finland
Intubation
7.4
6.5
15
24
ZXC07
NOMESCO Finland
Carbon dioxide laser
75.3
6.5
7
*
QBA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of trunk
+∞
6.3
6
*
D07XB05
ATC
dexamethasone; topical
14.0
6.3
10
8
D02AE01
ATC
carbamide; topical
6.8
6.2
15
26
J01DA01
ATC
[U] cefalexin
3.7
6.1
66
417
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
8
7.96
3.11
1.0
1.3
—
—
—
0
0
5
5
10.51
3.01
1.2
1.2
—
—
—
0
0
7
14
5.35
2.79
1.3
1.6
—
—
—
0
0
6
10
6.36
2.74
1.0
1.2
—
—
—
0
0
5
7
7.50
2.58
1.2
2.0
—
—
—
0
0
47
326
2.00
2.48
2.3
2.0
1.41
1.35
mmol/l
0.16
42
273
5
9
5.82
2.24
1.0
1.2
—
—
—
0
0
26
151
2.05
2.21
6.0
3.2
17.29
80.09
ng/l
1.08
21
112
48
346
1.90
2.16
3.7
2.7
—
—
estimate
—
0
0
5
11
4.76
1.97
1.2
1.4
—
—
—
0
0
7
24
3.09
1.76
1.1
1.3
—
2.63
—
0
6
28
181
1.82
1.70
1.2
1.3
1.90
2.70
u/ml
—
6
44
7
25
2.96
1.69
1.1
1.3
—
—
—
0
0
16
86
2.06
1.64
2.9
2.3
—
—
—
0
0
7
26
2.84
1.62
1.1
1.2
—
—
—
0
0
34
241
1.69
1.48
4.5
3.3
0.00
0.01
estimate
—
10
68
42
315
1.67
1.47
4.7
3.9
0.00
0.01
estimate
0.49
11
72
14
75
2.04
1.44
5.4
3.7
—
—
—
0
0
39
293
1.62
1.33
2.9
4.4
40.05
24.61
ng/l
0.27
25
208
8
36
2.35
1.28
2.7
10.0
24.31
24.82
mmol/l
—
8
36
51
412
1.61
1.27
4.9
3.8
0.00
0.00
estimate
-0.00
12
88
50
406
1.57
1.18
4.9
3.8
0.00
0.00
estimate
-0.00
12
85
15
89
1.83
1.17
3.3
2.1
—
—
—
0
0
25
176
1.60
1.08
4.4
4.1
1.02
1.02
kg/l
0.24
17
116
18
117
1.69
1.04
2.9
2.3
—
—
—
0
0
50
414
1.51
1.03
4.9
3.9
0.00
0.00
estimate
-0.00
12
79
42
338
1.49
0.98
2.5
2.0
91.07
97.36
pmol/l
0.40
22
170
0
24
0.00
0.80
0.0
2.2
—
—
—
0
0
0
24
0.00
0.80
0.0
1.3
—
0.00
—
0
24
0
25
0.00
0.80
0.0
1.3
—
0.00
—
0
25
0
25
0.00
0.80
0.0
2.6
—
—
—
0
0
0
27
0.00
0.79
0.0
1.6
—
1.04
—
0
27
18
126
1.55
0.78
1.7
1.6
—
—
—
0
0
51
440
1.40
0.75
9.9
11.7
4.19
4.14
e9/l
0.05
44
391
5
26
1.98
0.72
1.2
1.7
80.40
44.92
nmol/l
—
5
26
22
165
1.45
0.70
1.3
1.4
12.75
6.52
u/ml
—
6
65
33
268
1.38
0.68
3.7
3.6
9.75
8.41
mg/mmol
0.06
20
161
42
357
1.35
0.64
2.1
2.7
81.67
102.42
ug/l
0.73
35
342
5
30
1.71
0.62
1.0
1.3
0.24
0.23
g/l
—
5
30
5
30
1.71
0.62
1.0
1.3
1.21
1.21
g/l
—
5
30
0
20
0.00
0.61
0.0
1.6
—
—
—
0
0
28
232
1.31
0.49
3.0
2.7
0.06
0.37
e6/l
2.52
22
171
69
728
0.71
0.49
5.7
5.2
6.02
5.84
mmol/l
0.91
62
681
39
340
1.27
0.46
5.6
6.3
1.19
1.21
mmol/l
1.50
39
316
33
283
1.27
0.44
2.9
3.1
—
—
—
0
0
22
179
1.31
0.43
1.5
1.4
56.25
27.17
iu/ml
—
8
67
17
134
1.34
0.41
2.8
2.7
0.86
0.99
e6/l
—
7
72
15
116
1.36
0.40
3.1
3.0
3.14
2.20
e6/l
—
5
54
0
18
0.00
0.40
0.0
2.8
—
—
—
0
0
9
66
1.41
0.40
1.3
2.8
9.09
4.86
ug/l
—
9
60
6
42
1.46
0.36
1.7
2.5
22.40
24.04
mmol/l
—
6
42
8
63
1.30
0.29
1.8
2.6
16.06
13.85
nmol/l
—
8
63
76
740
1.28
0.22
21.9
16.5
23.44
21.79
mg/l
0.19
68
601
5
41
1.23
0.22
7.2
9.0
21.80
24.91
mmol/l
—
5
41
5
42
1.20
0.22
2.2
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
7.80
—
0
5
6
47
1.30
0.21
5.5
3.6
34.50
65.32
u/ml
—
6
47
0
13
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
4.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
1.15
—
0
8
0
14
0.00
0.20
0.0
1.6
—
0.97
—
0
8
0
14
0.00
0.20
0.0
1.6
—
0.93
—
0
8
8
69
1.18
0.17
1.6
1.3
—
—
—
0
0
9
77
1.19
0.16
1.4
2.1
—
—
—
0
0
9
82
1.11
0.15
6.2
8.5
—
—
—
0
0
20
182
1.13
0.12
4.2
5.0
20.76
22.22
%
—
5
85
14
125
1.14
0.11
1.1
1.5
—
—
—
0
0
70
715
0.87
0.11
19.8
15.6
83.76
80.92
ml/min/173m2
0.63
70
671
56
543
1.09
0.10
3.8
3.3
49.92
41.78
u/l
0.25
51
519
9
83
1.09
0.07
1.3
1.8
1.41
1.56
%
—
9
75
24
227
1.08
0.07
6.2
4.0
0.00
0.00
estimate
-0.00
11
80
18
172
1.06
0.02
3.6
2.4
—
—
—
0
0
72
714
1.06
0.01
6.8
6.3
39.88
39.13
mmol/mol
0.32
66
676
71
709
1.01
0.00
5.4
4.5
1.29
1.27
mmol/l
0.15
63
660
74
741
0.99
0.00
6.8
5.4
4.61
4.60
mmol/l
0.02
69
699
44
444
0.98
0.00
3.5
3.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
198.24
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
8.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
8.3
—
148.75
—
0
8
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
7
69
1.02
-0.00
1.4
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
4.60
—
0
5
76
757
1.04
-0.00
26.5
18.2
4.00
3.96
mmol/l
0.82
76
744
0
5
0.00
-0.00
0.0
2.4
—
10.46
—
0
5
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
40.53
—
0
6
0
7
0.00
-0.00
0.0
2.0
—
14.00
—
0
7
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.3
—
1.11
—
0
9
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_FAMILIAL_BENIGN_PEMPHIGUS – Familial benign pemphigus (Hailey-Hailey disease)
GWS hits: 14
This endpoint is excluded (different definition than used in FinnGen).