Primary adrenocortical insufficiency

E4_PRIMARY_ADRENOCORTICAL_INSUFFICIENCY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E27.1
  • Cause of death: ICD-10 E27.1

2 out of 7 registries used, show all original rules.

464

4. Check minimum number of events

None

464

5. Include endpoints

None

464

6. Filter based on genotype QC (FinnGen only)

416

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 416 283 133
Unadjusted period prevalence (%) 0.09 0.10 0.06
Median age at first event (years) 52.13 50.67 55.25

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
423
Matched controls
4230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
307.7
423
*
H02AB09
ATC
hydrocortisone; systemic
837.4
307.7
377
41
H02AA02
ATC
fludrocortisone; oral
739.2
281.3
248
8
105
Kela drug reimbursment
Adrenal cortical hypofunction
6013.9
276.8
236
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
278.2
107.0
105
5
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
23.3
104.9
80
42
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
15.0
96.8
94
79
H03AA01
ATC
levothyroxine sodium; systemic
5.8
72.7
225
690
E27.2
ICD-10 Finland
Addisonian crisis
+∞
70.9
66
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
5.0
57.6
186
572
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
118.5
57.5
61
6
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
5.0
48.6
138
376
E23.03
ICD-10 Finland
Lack of ACTH
263.6
47.0
47
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
7.9
45.0
67
98
R11
ICD-10 Finland
Nausea and vomiting
5.4
44.1
104
241
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
9.4
42.5
54
65
104
Kela drug reimbursment
Thyroid insufficiency
5.9
41.7
86
176
25510
ICD-8 Finland
Diseases of adrenal glands, Adrenal cortical hypofunction
+∞
38.1
36
*
H04AA01
ATC
glucagon; nasal, parenteral
9.3
35.0
44
52
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.5
34.0
187
786
2554A
ICD-9 Finland
Disorders of adrenal glands, Corticoadrenal insufficiency[MORBUS ADDISON PRIMARIUS]
+∞
31.7
30
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.3
31.6
213
1003
T89
ICPC
Diabetes insulin dependent
6.6
30.7
53
90
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
8.4
29.4
40
52
A41.9
ICD-10 Finland
Sepsis, unspecified
7.7
29.4
43
61
A10AB05
ATC
insulin aspart; parenteral
4.7
29.0
75
184
E87.5
ICD-10 Finland
Hyperkalaemia
10.4
28.0
32
33
R50.9
ICD-10 Finland
Fever, unspecified
3.6
28.0
116
401
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.2
27.9
85
237
M05BA04
ATC
alendronic acid; oral
4.6
27.3
73
184
E86
ICD-10 Finland
Volume depletion
9.3
26.6
33
38
E87.6
ICD-10 Finland
Hypokalaemia
7.1
26.5
42
65
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.7
26.2
99
321
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
25.5
249
1393
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.6
25.1
33
41
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.7
24.8
63
152
R53
ICD-10 Finland
Malaise and fatigue
2.9
24.0
178
855
A10AB04
ATC
insulin lispro; parenteral
6.2
23.9
43
76
A10AE05
ATC
insulin detemir; parenteral
5.0
23.1
53
117
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
9.9
22.9
27
29
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.6
22.8
38
62
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
22.8
91
304
E27.0
ICD-10 Finland
Other adrenocortical overactivity
63.4
21.1
24
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
8.1
21.1
29
38
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.7
21.0
77
242
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
21.0
106
407
101
Kela drug reimbursment
Anterior pituitary hypofunction
39.4
21.0
26
7
E27.9
ICD-10 Finland
Disorder of adrenal gland, unspecified
+∞
21.0
20
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.5
20.9
43
86
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
20.6
98
363
121
Kela drug reimbursment
Severe hypofunction of sexual glands
7.7
20.2
29
40
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.8
19.7
28
38
E03.89
ICD-10 Finland
Other specified hypothyroidism
5.2
19.4
42
88
A10AB01
ATC
insulin (human); parenteral
5.5
19.0
38
74
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.9
18.6
61
177
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
24.1
18.0
25
11
A10AC01
ATC
insulin (human); parenteral
3.6
17.9
64
197
M05BX04
ATC
denosumab; parenteral
4.3
17.9
50
129
E23.00
ICD-10 Finland
Panhypopituitarism
69.7
17.9
20
*
A10AA01, ,
ATC
6.3
17.2
30
51
C03CA01
ATC
furosemide; systemic
2.5
16.9
152
777
C03DA01
ATC
spironolactone; oral
3.2
16.5
73
257
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
16.4
68
230
J46
ICD-10 Finland
Status asthmaticus
6.3
16.3
28
47
JN3AD
NOMESCO Finland
Abdominal CT examination
3.0
16.1
84
325
N02AA05
ATC
oxycodone; systemic
2.7
16.1
107
472
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
4.8
16.0
37
82
A07AA02
ATC
nystatin; oral
4.0
15.9
48
131
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
20.2
15.7
23
12
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
5.5
15.6
31
60
UJF32
NOMESCO Finland
Coloscopy
2.5
15.4
134
670
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
15.4
139
707
J45.8
ICD-10 Finland
Mixed asthma
5.9
15.3
28
50
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
15.8
15.1
24
16
J01MA12
ATC
levofloxacin; systemic
2.6
14.8
100
443
J01MA02
ATC
ciprofloxacin; systemic
2.3
14.8
191
1130
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
14.7
119
574
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.3
14.7
40
101
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
16.1
14.6
23
15
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.0
14.5
32
68
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
6.5
14.4
24
39
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
5.1
14.0
30
62
B03BA03
ATC
hydroxocobalamin; parenteral
3.9
13.7
42
116
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.4
13.5
120
601
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
144.5
13.5
14
*
J45.9
ICD-10 Finland
Asthma, unspecified
2.5
13.5
109
523
A10AE04
ATC
insulin glargine; parenteral
3.1
13.4
62
223
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
13.4
120
604
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.0
13.3
29
61
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
13.2
86
372
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
29.4
13.1
17
6
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.9
13.0
29
62
103
Kela drug reimbursment
Diabetes, insulin-treated
2.3
12.9
128
671
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.5
12.8
101
478
N06AA09
ATC
amitriptyline; systemic
3.1
12.7
59
213
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
10.5
12.6
24
24
E31.08
ICD-10 Finland
Autoimmune polyglandular failure
+∞
12.6
12
*
E31.00
ICD-10 Finland
APECED syndrome
+∞
12.6
12
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.2
12.3
34
87
N03AX16
ATC
[U] pregabalin
2.3
11.9
120
631
A10AA02, ,
ATC
4.6
11.9
29
67
N03AE01
ATC
clonazepam; systemic
3.8
11.9
38
108
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
11.8
56
204
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
4.8
11.8
27
59
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
11.8
83
372
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
11.7
177
1089
A10AE06
ATC
insulin degludec; parenteral
4.3
11.6
31
77
AA1AD
NOMESCO Finland
CT of head and brain
2.2
11.6
140
791
L28
ICPC
Limited function/disability (L)
2.3
11.4
103
516
H02AB06
ATC
prednisolone; systemic
2.0
11.2
226
1535
H02AB07
ATC
prednisone; oral
2.6
11.2
75
328
R03AC12
ATC
salmeterol; inhalant
3.8
11.2
35
98
N06AX21
ATC
duloxetine; oral
2.6
11.1
75
329
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.9
11.1
25
54
M05BA07
ATC
risedronic acid; oral
4.9
11.1
25
54
J01FF01
ATC
clindamycin; systemic
2.1
10.9
133
751
SPAT1254
SPAT
Administration of medicine
2.5
10.9
78
352
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.1
10.9
31
81
K90.0
ICD-10 Finland
Coeliac disease
4.8
10.9
25
55
A04
ICPC
Weakness/tiredness general
2.3
10.8
92
448
WX882
NOMESCO Finland
High dependency care
5.8
10.8
20
36
XF600
NOMESCO Finland
Bloodpressure measurement
3.3
10.8
42
136
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
10.7
56
215
A02BC02
ATC
pantoprazole; systemic
2.1
10.7
304
2317
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.4
10.7
82
382
J01MA14
ATC
moxifloxacin; systemic
2.9
10.6
52
193
R03BB04
ATC
tiotropium bromide; inhalant
2.8
10.5
55
212
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
112.7
10.5
11
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
112.7
10.5
11
*
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
12.5
10.4
18
15
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
12.5
10.4
18
15
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.6
10.4
25
57
R03DC03
ATC
montelukast; oral
2.3
10.3
94
472
WX892
NOMESCO Finland
Monitored bed care
3.1
10.3
44
151
R02
ICPC
Shortness of breath/dyspnoea
2.4
10.2
76
348
A11CC03
ATC
alfacalcidol; systemic
5.5
10.2
20
38
107
Kela drug reimbursment
Pernicious anaemia
7.9
10.0
22
29
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
9.9
54
212
N05CF01
ATC
zopiclone; oral
2.0
9.9
158
978
I95.1
ICD-10 Finland
Orthostatic hypotension
4.3
9.8
26
64
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
9.8
58
238
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
4.5
9.7
24
56
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.1
9.7
42
145
318
Kela drug reimbursment
Teriparatide
56.3
9.7
11
*
H3600, E103,
ICD-10 Finland
11.8
9.6
17
15
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
7.4
9.6
22
31
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
9.6
149
912
ZX120
NOMESCO Finland
Intravenous
2.7
9.5
55
223
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.2
9.5
100
531
E27
ICD-10 Finland
Other disorders of adrenal gland
+∞
9.4
9
*
E28.3
ICD-10 Finland
Primary ovarian failure
22.3
9.4
13
6
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.9
9.4
21
45
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
4.2
9.4
25
62
SPAT1262
SPAT
Handing over of treatment supplies
2.3
9.4
82
403
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
9.8
9.4
18
19
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
9.3
88
446
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
4.6
9.2
22
50
B81
ICPC
Anaemia vit B12/folate deficiency
4.0
9.1
26
68
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.6
9.1
30
87
N03AX12
ATC
[U] gabapentin; oral
2.2
9.1
88
451
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
19.1
9.0
13
7
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
8.9
61
268
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
12.9
8.9
15
12
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.3
8.8
71
336
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.6
8.8
29
84
R06.0
ICD-10 Finland
Dyspnoea
2.0
8.8
135
819
A46
ICD-10 Finland
Erysipelas
2.3
8.7
70
331
H05AA02
ATC
teriparatide; parenteral
51.1
8.7
10
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.3
8.7
33
105
N03AG01
ATC
valproic acid; systemic, rectal
3.1
8.7
38
132
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.2
8.6
23
57
106
Kela drug reimbursment
Hypoparathyroidism
28.2
8.5
11
*
Z3231
NOMESCO Finland
Registered nurse
1.9
8.5
131
795
E27.8
ICD-10 Finland
Other specified disorders of adrenal gland
91.8
8.4
9
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.8
8.4
19
41
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
11.1
8.4
15
14
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.7
8.3
46
182
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.1
8.3
35
119
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.7
8.3
26
73
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
8.1
47
190
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
8.1
55
241
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.4
8.1
29
89
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
8.0
55
242
A06AD11
ATC
lactulose; oral
2.2
8.0
72
357
UJD02
NOMESCO Finland
Gastroscopy
3.3
8.0
30
95
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
8.0
78
400
M01AH01
ATC
celecoxib; oral
2.1
8.0
85
451
H03BB01
ATC
carbimazole; oral
3.4
8.0
29
90
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.9
7.9
38
139
R4190
NOMESCO Finland
Nutritional therapy
3.5
7.9
28
85
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
11.1
7.8
14
13
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
11.1
7.8
14
13
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.1
7.8
33
112
R60.9
ICD-10 Finland
Oedema, unspecified
3.1
7.8
33
112
A12AA04
ATC
calcium carbonate; oral
9.7
7.8
15
16
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.5
7.8
53
232
R03DA04
ATC
theophylline; systemic, rectal
3.2
7.8
31
102
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
7.7
125
767
J02AC01
ATC
fluconazole; systemic
1.8
7.7
188
1308
K59.09
ICD-10 Finland
Constipation, unspecified
2.8
7.7
40
153
N02AX02
ATC
tramadol; systemic, rectal
1.8
7.7
188
1310
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
7.7
116
696
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
7.7
176
1203
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
7.6
92
510
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
7.6
110
650
WZC30
NOMESCO Finland
Teaching
2.1
7.6
81
429
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.2
7.6
30
98
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.8
7.5
39
149
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.7
7.5
40
155
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
7.5
186
1298
N06AB04
ATC
citalopram; systemic
2.0
7.5
101
583
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
7.4
44
180
BCA30
NOMESCO Finland
Unilateral adrenalectomy
81.5
7.4
8
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
7.4
57
264
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
3.4
7.4
27
84
E25.01
ICD-10 Finland
Congenital adrenal hyperplasia
+∞
7.3
7
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
7.3
192
1360
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
4.4
7.3
18
42
M81.4
ICD-10 Finland
Drug-induced osteoporosis
16.1
7.3
11
7
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.7
7.3
39
152
SPAT1260
SPAT
Consultation of another employee
2.1
7.2
82
444
WVA30, ,
SPAT
2.8
7.2
36
135
A02BA02
ATC
ranitidine; systemic
2.0
7.2
90
505
R42
ICD-10 Finland
Dizziness and giddiness
1.9
7.2
108
645
M48.0
ICD-10 Finland
Spinal stenosis
2.3
7.2
59
281
R52.2
ICD-10 Finland
Other chronic pain
3.2
7.2
29
96
K29.4
ICD-10 Finland
Chronic atrophic gastritis
6.8
7.2
17
26
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.9
7.2
21
56
H3603, E103,
ICD-10 Finland
20.4
7.2
10
5
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
20.4
7.2
10
5
D51.0
ICD-10 Finland
Vitamin B12deficiency anaemia due to intrinsic factor deficiency
12.3
7.1
12
10
SPAT1229
SPAT
Assessment of need for aid
2.7
7.1
39
154
H3601, E103,
ICD-10 Finland
10.3
7.1
13
13
R03AK08
ATC
formoterol and beclometasone; inhalant
3.1
7.1
29
97
N05BA01
ATC
diazepam; systemic, rectal
2.2
7.0
65
325
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.1
7.0
30
103
H02AB04
ATC
methylprednisolone; systemic
2.2
7.0
67
340
R13
ICD-10 Finland
Dysphagia
2.6
7.0
40
161
N05CD07
ATC
temazepam; oral
2.3
6.9
53
246
N91.1
ICD-10 Finland
Secondary amenorrhoea
6.3
6.8
17
28
Z50.1
ICD-10 Finland
Other physical therapy
3.0
6.8
30
105
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
40.7
6.8
8
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.0
6.7
29
100
ZXD05
NOMESCO Finland
Urgent procedure
1.8
6.7
135
881
N03AX14
ATC
levetiracetam; systemic
4.1
6.7
18
45
M54.5
ICD-10 Finland
Low back pain
1.7
6.7
171
1195
K59.1
ICD-10 Finland
Functional diarrhoea
2.7
6.6
36
141
SPAT1255
SPAT
Intravenous administration of medicine
2.9
6.6
31
112
R55
ICD-10 Finland
Syncope and collapse
2.2
6.6
57
277
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
12.5
6.6
11
9
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.9
6.6
19
50
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
6.6
40
166
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
6.6
64
327
A03CA02
ATC
clidinium and psycholeptics; oral
3.1
6.6
28
96
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.6
6.5
21
60
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
6.5
51
238
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
6.4
232
1774
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.6
6.4
21
61
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.6
6.4
21
61
R03DC01
ATC
zafirlukast; oral
5.7
6.4
17
31
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
6.4
153
1048
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
6.3
47
215
E31.0
ICD-10 Finland
Autoimmune polyglandular failure
+∞
6.3
6
*
2581B
ICD-9 Finland
Polyglandular dysfunction and related disorders, Other combinations of endocrine dysfunction[AUTOIMMUNE-POLYENDOCRINOPATHY-CANDIDOSIS-ECTOD DYST]
+∞
6.3
6
*
E25.00
ICD-10 Finland
Congenital salt-losing adrenal hyperplasia
+∞
6.3
6
*
E31.01
ICD-10 Finland
Schmidt's syndrome
+∞
6.3
6
*
V04CD01
ATC
metyrapone; oral
+∞
6.3
6
*
E000001, ,
ATC
1.9
6.2
91
536
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
6.2
135
897
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
6.2
98
592
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
6.4
6.2
15
24
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
6.2
69
371
N06AX16
ATC
venlafaxine; oral
2.0
6.1
73
401
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.2
6.1
16
39
SBA00
NOMESCO Finland
Microbiological examinations
4.2
6.1
16
39
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.8
6.1
31
117
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
3.7
6.1
19
53
R41.0
ICD-10 Finland
Disorientation, unspecified
3.7
6.1
19
53
B37.08
ICD-10 Finland
Other candidal stomatitis
8.8
6.1
12
14
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
5.3
6.1
17
33
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
6.1
52
252
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.0
6.0
17
44
A01
ICPC
Pain general/multiple sites
2.2
6.0
54
267

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
163
37
71.05
287.57
3.0
1.4
275.34
23.23
ng/l
10.00
163
37
271
385
17.81
208.91
5.6
2.2
269.02
382.11
nmol/l
5.26
248
359
74
5
178.74
72.58
1.3
1.0
34.34
—
titre
—
35
0
59
51
13.28
58.86
1.7
1.2
254.50
312.85
pmol/l
0.38
40
46
121
258
6.17
57.18
4.2
3.8
4.46
4.52
pmol/l
0.26
109
229
347
1819
6.05
52.07
17.0
7.3
1.20
1.21
mmol/l
2.52
305
1584
233
929
4.36
49.78
6.4
4.3
—
—
—
0
0
155
461
4.73
48.97
6.7
5.9
1.07
1.04
mmol/l
0.58
149
422
320
1643
4.89
47.32
15.3
6.6
1.20
1.22
mmol/l
2.87
312
1523
56
65
9.78
45.40
1.4
1.2
43.04
18.86
iu/ml
0.50
21
14
256
1147
4.12
45.15
9.5
4.0
7.40
7.40
ph
0.11
205
797
172
602
4.13
42.89
5.0
3.6
0.79
0.82
mmol/l
2.19
164
570
306
1697
3.90
36.28
4.9
2.7
77.90
76.71
nmol/l
0.33
290
1538
218
991
3.48
35.19
2.1
1.3
1.41
1.77
u/ml
0.20
65
272
41
44
10.21
35.02
1.6
1.1
266.59
273.97
mosm/kgh2o
0.64
34
36
104
306
4.18
32.00
1.5
1.2
298.69
157.74
u/ml
1.45
40
126
198
889
3.31
31.89
2.2
1.5
2.07
2.27
g/l
1.06
130
549
133
480
3.58
30.26
12.3
7.1
101.80
104.06
mmol/l
3.69
133
480
169
723
3.23
29.00
3.9
2.8
479.27
514.92
mosm/kgh2o
1.30
151
640
334
2120
3.74
28.77
10.8
5.2
7.15
6.55
mmol/l
2.78
326
1994
113
380
3.69
28.46
11.0
9.0
0.79
1.01
mmol/l
0.21
91
319
83
228
4.28
27.77
8.4
8.2
25.39
24.82
mmol/l
0.51
83
228
71
174
4.70
27.47
2.4
1.6
342.06
322.82
mu/l
0.22
62
156
109
366
3.66
27.43
6.1
4.1
7.39
7.38
ph
0.05
70
211
92
275
4.00
27.41
3.5
3.7
59.02
80.31
ng/l
2.65
73
240
106
350
3.71
27.35
6.5
4.0
1.72
1.87
mmol/l
0.13
90
303
108
363
3.65
27.11
7.0
4.0
5.79
5.73
kpa
0.27
102
358
138
544
3.28
26.87
3.2
2.5
2.21
2.35
g/l
2.28
127
502
110
378
3.58
26.66
11.5
9.2
7.42
7.42
ph
0.16
69
222
42
66
6.95
26.13
4.8
2.8
—
—
—
0
0
50
94
5.90
26.09
4.8
2.9
7.42
7.42
ph
0.05
50
94
110
384
3.52
25.96
11.6
9.0
12.42
12.42
kpa
0.00
105
374
141
591
3.08
24.41
3.3
2.5
12.87
13.27
umol/l
0.25
129
550
95
316
3.59
24.01
7.2
3.7
4.05
4.54
kpa
2.33
88
310
127
509
3.14
23.68
3.3
2.5
25.35
22.46
%
1.19
119
475
93
310
3.56
23.38
10.4
8.4
—
—
—
0
0
265
1578
2.82
23.30
8.8
4.7
34.57
36.09
g/l
4.52
256
1485
190
972
2.73
22.29
3.4
2.3
2.77
2.93
mg/l
0.49
173
837
55
130
4.71
22.10
1.6
1.3
17.81
10.59
u/l
1.61
47
105
260
1567
2.71
21.75
3.1
2.1
96.05
96.69
pmol/l
0.09
170
804
206
1110
2.67
21.62
3.3
2.2
182.58
254.69
u/l
0.53
200
1062
91
316
3.39
21.34
12.4
9.8
122.52
120.86
g/l
0.33
91
310
36
60
6.47
21.12
4.6
2.5
8.42
8.91
kpa
0.82
36
60
36
60
6.47
21.12
4.6
2.5
5.11
4.97
kpa
0.43
36
60
36
60
6.47
21.12
4.6
2.5
3.90
2.92
mmol/l
0.59
27
36
218
1227
2.60
20.65
8.2
6.3
—
—
—
0
0
90
330
3.19
19.17
2.5
2.7
0.21
0.22
g/l
0.78
81
309
85
304
3.25
18.86
3.7
3.1
9.62
10.30
g/l
0.81
77
288
37
71
5.61
18.79
1.8
1.4
0.33
0.36
nmol/l
0.11
29
55
294
1969
2.62
18.47
10.4
6.1
10.29
10.95
umol/l
0.86
289
1873
49
123
4.37
18.18
2.7
1.7
2.97
3.28
ug/l
0.05
44
111
70
227
3.50
18.12
5.4
3.8
7.41
7.42
ph
0.48
65
190
276
1812
2.51
17.81
8.8
6.6
27.06
28.30
%
0.97
271
1728
46
113
4.45
17.53
2.2
2.0
150.37
3.62
iu/l
0.51
22
44
378
2923
3.76
17.46
11.7
4.6
15.71
14.70
pmol/l
11.17
364
2705
270
1771
2.45
17.20
9.0
6.6
2.22
2.82
%
5.12
265
1668
270
1775
2.44
17.06
9.2
6.7
8.23
8.63
%
1.60
265
1676
35
70
5.36
16.98
2.9
1.9
4.46
4.49
mmol/24h
0.02
29
60
286
1938
2.47
16.74
9.1
6.6
0.04
0.04
e9/l
0.62
261
1686
292
1999
2.49
16.68
9.3
7.0
0.16
0.19
e9/l
2.97
266
1770
124
579
2.62
16.67
1.6
1.4
650.00
517.91
titre
0.26
16
134
289
1970
2.47
16.66
9.1
6.7
1.93
1.91
e9/l
0.08
266
1760
285
1931
2.46
16.65
9.1
6.6
0.61
0.56
e9/l
2.46
260
1684
270
1790
2.41
16.51
8.7
6.5
58.08
57.11
%
0.55
265
1715
267
1766
2.39
16.34
9.3
6.7
0.58
0.70
%
3.18
260
1656
251
1620
2.35
16.21
14.6
11.9
1.15
1.19
inr
0.84
225
1340
200
1176
2.33
16.04
4.5
2.5
50.67
60.96
u/l
1.55
193
1097
62
202
3.42
15.86
12.3
9.1
23.39
24.49
mmol/l
1.12
62
194
211
1275
2.31
15.79
5.3
3.2
2.33
2.36
mmol/l
1.75
203
1157
157
845
2.36
15.31
3.7
2.7
6.27
6.65
e6/l
0.10
149
772
361
2794
2.99
15.05
16.0
7.9
76.33
78.12
u/l
0.32
356
2638
86
350
2.83
15.00
5.2
4.7
1.32
0.92
%
0.76
37
112
84
341
2.83
14.70
1.7
1.2
—
—
—
0
0
82
329
2.85
14.66
5.2
4.8
0.09
0.18
%
0.60
33
90
40
102
4.23
14.50
2.3
2.4
8.01
12.37
mg/l
2.78
35
96
69
256
3.03
14.19
2.1
1.7
1.21
1.35
g/l
0.30
63
239
300
2160
2.34
14.04
12.9
10.0
4.89
4.05
e9/l
5.47
274
1893
253
1700
2.21
14.02
22.6
11.3
0.00
0.00
e9/l
0.77
216
1412
177
1042
2.20
13.59
4.4
3.1
0.26
0.33
e6/l
0.49
148
761
197
1218
2.16
13.27
4.8
3.3
18.44
89.45
e6/l
0.74
167
933
57
201
3.12
12.75
5.9
3.5
0.64
0.61
%
0.36
57
201
19
11
18.00
12.62
1.2
2.2
1.06
1.18
ug/l
0.08
19
11
94
436
2.49
12.46
2.6
1.6
—
—
—
0
0
51
174
3.20
12.04
11.7
12.2
16.38
16.03
%
0.45
51
167
77
330
2.63
12.00
4.9
4.5
0.66
0.58
%
0.18
29
100
79
343
2.60
11.99
5.4
5.1
0.00
0.16
%
0.91
27
86
27
59
4.82
11.82
3.0
3.4
4.81
4.59
e9/l
0.16
27
59
165
995
2.08
11.47
4.4
3.0
—
0.00
estimate
—
0
5
174
1080
2.04
11.10
2.1
1.7
20.00
20.79
nmol/l
0.32
156
919
101
510
2.29
10.94
1.5
1.2
—
—
—
0
0
101
512
2.28
10.83
2.8
2.0
—
—
—
0
0
87
416
2.37
10.67
2.3
3.3
1.88
1.83
%
0.14
71
380
22
44
5.22
10.63
1.6
4.8
206.83
62.31
u/ml
—
6
17
109
576
2.20
10.54
2.1
1.7
1309.17
1210.35
nmol/l
0.47
91
439
70
305
2.55
10.48
2.6
3.2
75.69
72.63
e9/l
0.24
53
227
210
1413
1.97
10.47
5.9
4.0
25.75
85.40
e6/l
2.78
171
980
207
1388
1.96
10.41
6.7
3.8
25.18
75.44
ng/l
0.60
160
919
22
45
5.10
10.37
3.0
1.3
—
—
nmol/l
—
0
0
69
303
2.53
10.16
4.9
3.9
—
—
—
0
0
30
81
3.91
10.05
3.3
3.2
62.07
58.52
%
0.73
30
81
39
126
3.31
10.04
10.5
8.3
0.96
0.85
%
0.85
39
116
66
287
2.54
9.91
2.0
3.0
64.60
67.09
g/l
2.15
60
272
62
264
2.58
9.71
4.2
2.5
11.72
13.22
nmol/l
0.68
55
249
150
921
1.97
9.57
7.0
5.1
—
—
—
0
0
55
223
2.69
9.49
1.4
1.2
—
—
—
0
0
16
13
12.74
9.43
2.6
1.2
931.56
49.69
nmol/24h
0.70
16
13
21
46
4.75
9.16
2.0
1.3
2.56
2.75
g/l
0.19
14
36
21
46
4.75
9.16
2.0
1.3
6.28
6.47
g/l
0.09
14
37
21
46
4.75
9.16
2.0
1.3
0.39
0.37
g/l
0.12
14
36
255
1882
1.89
9.15
4.9
3.1
122.70
97.74
ug/l
1.42
241
1778
193
1304
1.88
9.13
5.5
3.2
86.93
31.00
u/l
0.62
184
1245
56
234
2.61
9.10
1.7
2.8
—
—
—
0
0
41
148
2.96
8.77
12.1
7.4
1.59
1.56
%
0.07
41
138
143
889
1.92
8.64
2.4
1.8
0.79
1.11
mg/l
1.77
108
701
42
156
2.88
8.54
1.9
2.3
1.37
1.42
g/l
0.15
36
140
84
433
2.17
8.50
3.9
2.8
4.99
7.84
umol/l
2.09
64
389
123
733
1.96
8.39
5.2
2.7
2.47
2.45
mmol/l
0.82
113
653
27
77
3.68
8.39
1.8
1.9
0.59
0.71
g/l
0.18
19
67
57
250
2.48
8.37
1.7
1.3
26.04
23.43
iu/l
0.22
48
215
175
1178
1.83
8.13
5.1
3.1
—
—
—
0
0
20
47
4.42
8.02
2.3
1.3
—
—
—
0
0
158
1035
1.84
7.99
4.6
3.4
1116.46
1009.70
ng/l
0.19
141
878
97
543
2.02
7.85
2.0
2.6
145.90
104.80
ug/g
0.57
84
428
20
48
4.32
7.82
3.0
1.3
0.31
0.18
nmol/l
0.96
14
30
123
749
1.91
7.79
2.3
1.7
454.97
18196392.59
pmol/l
0.50
104
643
40
155
2.75
7.52
5.5
3.8
—
—
—
0
0
26
79
3.44
7.37
4.0
2.9
6.12
8.69
pmol/l
0.94
26
79
30
100
3.15
7.35
1.3
4.1
1.28
3.15
ratio
1.39
16
62
32
112
3.01
7.23
1.3
4.4
27.27
52.63
mg/l
1.39
23
98
41
165
2.64
7.17
1.3
1.7
—
14.34
—
0
7
86
478
2.00
7.05
4.1
3.2
5.03
6.58
e9/l
0.59
76
430
173
1199
1.75
7.04
4.6
3.2
6.51
7.67
mmol/l
3.19
155
1023
42
175
2.55
6.85
1.5
1.2
0.28
2.54
u/ml
—
6
11
14
18
8.00
6.66
4.1
3.2
268.29
158.22
nmol/l
0.23
14
18
31
112
2.91
6.63
1.4
4.4
22.40
46.51
mg/l
0.68
22
96
216
1620
1.68
6.40
4.8
3.5
6.30
6.22
ph
0.49
117
924
35
138
2.67
6.38
1.3
1.3
—
—
—
0
0
69
369
2.04
6.26
3.2
2.2
28.53
36.19
u/l
1.01
60
309
383
3405
2.32
6.24
13.6
5.6
2.76
1.86
mu/l
0.48
367
3170
81
473
1.88
5.68
2.0
1.4
—
—
—
0
0
21
66
3.30
5.67
1.2
1.1
—
—
—
0
0
17
47
3.73
5.54
1.8
2.0
31.88
32.68
pg
0.36
17
47
94
581
1.79
5.49
4.2
3.0
5.62
3.05
e6/l
0.69
54
278
156
1126
1.61
5.06
6.1
4.2
0.00
0.00
estimate
0.50
85
411
373
3340
1.99
5.04
10.6
6.0
42.35
38.84
mmol/mol
6.22
364
3161
11
16
7.02
4.98
3.8
5.8
15.34
15.21
%
0.03
11
16
151
1086
1.61
4.95
4.9
3.4
82.74
50.73
mg/l
0.51
92
704
24
89
2.80
4.93
2.9
2.0
169.71
228.44
pmol/l
1.31
24
82
13
25
5.33
4.80
1.2
1.0
—
—
—
0
0
252
2051
1.57
4.76
6.4
4.0
0.00
0.01
estimate
0.50
81
414
250
2032
1.56
4.75
6.4
4.0
0.00
11.11
estimate
1.07
87
442
27
109
2.58
4.73
1.6
1.3
272.59
312.71
ug/g
0.47
17
62
18
58
3.20
4.69
8.3
13.5
99.28
104.98
mmol/l
2.07
18
52
18
58
3.20
4.69
8.3
13.5
13.33
11.04
mmol/l
1.54
18
52
15
43
3.58
4.65
2.3
3.4
—
—
—
0
0
152
1108
1.58
4.65
5.8
4.1
18.49
9.06
mg/mmol
0.80
92
696
247
2011
1.55
4.59
6.4
3.9
0.00
0.00
estimate
-0.00
87
428
154
1140
1.55
4.35
5.6
3.3
0.00
0.00
estimate
0.50
76
351
15
38
4.05
4.34
3.1
3.2
—
—
—
0
0
21
78
2.78
4.32
1.1
1.9
—
—
—
0
0
218
1743
1.52
4.29
3.5
2.7
—
—
estimate
—
0
0
56
320
1.86
4.18
3.3
2.5
0.31
0.36
e6/l
0.14
56
304
161
1213
1.53
4.16
3.2
2.3
—
—
—
0
0
21
80
2.71
4.13
1.3
1.5
1.08
0.91
nmol/l
0.26
14
68
129
928
1.56
4.10
3.4
2.7
336.57
331.89
umol/l
0.17
103
831
9
14
6.54
4.00
1.9
1.1
178.22
180.90
mmol/24h
—
9
14
23
94
2.53
3.95
4.3
3.4
0.85
1.76
index
0.61
13
54
194
1539
1.48
3.83
6.3
3.8
0.00
0.02
estimate
1.15
76
362
36
182
2.07
3.81
2.3
2.2
3.13
4616.93
u/l
1.84
16
79
149
1124
1.50
3.75
10.5
6.6
—
—
—
0
0
17
407
0.39
3.72
1.2
1.4
—
—
—
0
0
289
2495
1.50
3.64
5.6
3.9
—
0.33
—
0
6
7
9
7.88
3.57
2.3
2.2
24.71
28.44
%
—
7
9
9
18
5.08
3.38
1.0
1.4
144.56
139.89
nmol/l
—
9
18
12
33
3.71
3.31
2.3
2.4
40.44
41.08
%
0.04
12
33
47
274
1.80
3.31
3.2
2.4
2.93
6.29
ug/l
2.43
39
246
189
1527
1.43
3.23
2.4
1.9
1.50
1.37
mmol/l
0.96
165
1309
26
125
2.15
3.15
4.8
4.0
393.87
260.35
mg/l
0.31
15
48
9
20
4.57
3.13
2.2
4.1
607.00
676.20
u/ml
—
9
20
7
12
5.91
3.03
1.1
2.5
—
64.71
—
0
7
9
21
4.35
3.01
5.2
4.8
8.16
8.26
mmol/l
—
9
21
67
444
1.60
2.97
1.3
1.4
—
—
—
0
0
16
65
2.52
2.82
1.0
1.0
—
—
—
0
0
30
160
1.94
2.79
2.0
1.9
—
—
—
0
0
385
3608
1.75
2.78
39.9
15.2
22.45
22.19
mg/l
0.07
352
2938
15
331
0.43
2.71
1.7
1.8
3.66
3.50
mmol/l
—
7
240
8
19
4.27
2.69
2.0
1.9
69.50
77.24
ug/l
—
8
19
32
178
1.86
2.64
1.4
1.5
0.39
0.36
mg/l
0.05
12
77
17
75
2.32
2.54
1.2
1.3
171.00
156.47
au/ml
—
5
22
8
21
3.86
2.47
1.1
1.8
—
—
—
0
0
18
85
2.17
2.32
1.2
1.4
—
—
—
0
0
32
186
1.78
2.32
1.9
2.3
9.87
5.13
iu/ml
—
6
53
12
47
2.60
2.29
1.5
1.6
—
—
—
0
0
12
47
2.60
2.29
1.5
1.6
—
—
—
0
0
12
47
2.60
2.29
1.5
1.6
—
—
—
0
0
12
47
2.60
2.29
1.5
1.6
—
—
—
0
0
8
23
3.52
2.28
3.8
1.6
15.64
9.85
nmol/l
—
8
18
102
782
1.40
2.22
1.5
1.3
20.54
31.74
iu/ml
1.13
29
239
13
54
2.45
2.22
3.1
2.6
—
—
—
0
0
179
1503
1.33
2.18
2.2
2.0
—
—
—
0
0
22
116
1.95
2.15
1.8
1.2
—
—
—
0
0
11
43
2.60
2.09
4.5
2.6
3.95
3.90
mmol/l
0.19
11
43
11
43
2.60
2.09
4.5
2.6
105.55
106.05
mmol/l
0.08
11
43
9
31
2.94
2.08
1.8
1.5
—
—
—
0
0
9
31
2.94
2.08
1.6
1.7
—
—
—
0
0
10
37
2.74
2.08
3.3
5.5
8.63
11.32
%
—
10
37
25
141
1.82
2.01
1.2
1.4
—
—
—
0
0
5
11
4.59
1.94
1.0
1.0
—
—
—
0
0
9
33
2.76
1.94
1.6
1.2
127.33
105.61
pmol/l
—
9
33
13
59
2.24
1.86
1.3
1.2
—
—
—
0
0
5
12
4.20
1.83
2.0
4.1
46.10
58.38
%
—
5
12
8
29
2.79
1.80
2.1
1.7
—
—
—
0
0
17
88
1.97
1.77
1.1
1.2
—
—
—
0
0
8
30
2.70
1.73
1.9
3.3
1496.13
689.73
mg
—
8
30
10
40
2.54
1.67
1.4
1.1
—
—
—
0
0
10
43
2.36
1.60
4.9
2.6
1.19
1.19
mmol/l
—
10
43
20
116
1.76
1.51
1.3
1.2
—
—
—
0
0
88
702
1.32
1.48
7.6
3.9
340.75
256.99
ng/l
0.14
60
515
5
16
3.15
1.44
1.2
1.7
—
—
—
0
0
9
40
2.28
1.41
1.1
1.3
—
—
—
0
0
15
82
1.86
1.37
1.3
1.3
—
—
—
0
0
280
2586
1.24
1.33
6.2
3.3
68.47
43.45
u/l
1.76
266
2452
5
18
2.80
1.29
1.0
1.0
1625.80
1703.89
miu/ml
—
5
18
6
26
2.33
1.19
1.2
1.1
—
—
—
0
0
47
357
1.36
1.11
3.1
3.9
6.22
39.57
ug/l
0.86
38
295
8
41
1.97
1.09
1.0
1.1
—
—
—
0
0
13
217
0.59
1.09
1.2
1.1
—
—
—
0
0
25
170
1.50
1.07
1.1
1.2
—
—
—
0
0
46
351
1.35
1.07
2.9
2.2
0.00
0.04
estimate
0.49
14
80
7
34
2.08
1.03
1.1
2.9
—
—
—
0
0
5
107
0.46
1.02
1.0
1.4
—
—
—
0
0
129
1127
1.21
1.00
1.5
1.5
—
—
—
0
0
10
54
1.87
0.97
1.4
1.5
—
—
—
0
0
0
32
0.00
0.95
0.0
1.1
—
—
—
0
0
15
93
1.64
0.95
1.3
1.2
75.11
13.56
e6/l
—
9
68
7
37
1.91
0.94
1.0
1.3
—
—
—
0
0
8
146
0.54
0.94
1.3
1.1
1.58
1.56
g/l
—
8
146
9
52
1.75
0.93
1.6
1.2
—
—
—
0
0
6
28
2.16
0.92
1.5
1.4
88.00
77.96
umol/l
—
6
28
61
499
1.26
0.88
1.6
1.5
—
—
—
0
0
15
96
1.58
0.85
1.5
1.3
73.11
115.42
e6/l
—
9
74
8
141
0.56
0.84
1.0
1.1
—
0.66
—
0
15
25
180
1.41
0.84
2.4
2.3
—
—
—
0
0
6
32
1.89
0.82
1.0
1.1
—
—
—
0
0
355
3425
1.23
0.81
7.1
4.8
5.90
5.87
mmol/l
0.12
340
3184
39
306
1.30
0.78
1.6
1.4
—
—
—
0
0
6
34
1.78
0.76
1.0
1.3
—
—
—
0
0
10
160
0.62
0.75
1.4
1.4
309.40
251.44
miu/ml
—
5
78
5
24
2.10
0.74
1.6
1.2
—
—
—
0
0
20
142
1.43
0.73
1.5
1.8
—
—
—
0
0
37
464
0.78
0.73
3.3
3.0
0.97
0.78
ug/l
0.44
26
277
25
186
1.37
0.72
1.2
1.1
—
—
—
0
0
7
40
1.76
0.71
1.0
1.3
—
—
—
0
0
5
26
1.93
0.71
2.0
1.5
—
—
—
0
0
13
86
1.53
0.67
8.3
4.3
—
—
—
0
0
5
28
1.79
0.66
1.2
1.6
108.80
184.01
pmol/l
—
5
28
83
727
1.18
0.63
1.5
1.3
6.87
12.13
u/ml
0.61
32
293
16
113
1.43
0.62
1.7
2.6
—
—
—
0
0
13
88
1.49
0.61
1.2
1.8
—
—
—
0
0
38
309
1.25
0.61
1.7
1.4
—
—
—
0
0
297
3085
0.87
0.59
43.0
19.6
332.24
332.14
g/l
0.06
297
3071
10
150
0.66
0.59
1.9
1.2
0.90
0.90
g/l
—
10
150
6
35
1.72
0.58
1.5
1.0
—
—
—
0
0
8
55
1.46
0.56
1.6
1.5
—
—
—
0
0
57
489
1.19
0.56
1.7
1.6
—
—
—
0
0
100
900
1.15
0.54
6.4
4.1
1.01
1.02
kg/l
2.01
68
592
6
38
1.59
0.54
1.5
2.8
—
—
—
0
0
9
63
1.44
0.52
1.0
1.3
8.50
20.60
u/l
—
9
54
6
40
1.51
0.52
1.0
1.2
—
—
—
0
0
7
51
1.38
0.44
3.1
2.2
—
—
—
0
0
92
838
1.13
0.43
1.8
2.0
—
—
—
0
0
5
32
1.57
0.42
1.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
0.00
—
0
17
0
17
0.00
0.40
0.0
2.2
—
—
—
0
0
345
3371
1.13
0.40
5.3
4.1
1.44
1.26
mmol/l
1.52
321
3134
8
60
1.34
0.40
1.0
1.1
—
—
—
0
0
381
3747
1.17
0.40
35.8
13.2
—
—
—
0
0
77
702
1.12
0.36
1.8
1.7
—
—
—
0
0
6
43
1.40
0.35
4.2
2.4
—
—
—
0
0
145
1532
0.92
0.34
4.0
3.0
—
—
—
0
0
6
46
1.31
0.33
1.5
1.3
—
—
—
0
0
7
53
1.33
0.31
1.3
1.4
—
—
—
0
0
15
121
1.25
0.29
13.3
10.4
—
—
—
0
0
8
65
1.24
0.27
1.4
1.2
—
—
—
0
0
11
88
1.26
0.22
1.1
1.1
—
—
—
0
0
360
3553
1.09
0.22
6.5
4.9
4.71
4.69
mmol/l
0.12
340
3337
0
11
0.00
0.21
0.0
3.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
4.19
—
0
10
0
10
0.00
0.21
0.0
2.3
—
33.40
—
0
10
0
10
0.00
0.21
0.0
4.6
—
8.60
—
0
10
0
12
0.00
0.21
0.0
1.3
—
9.60
—
0
12
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
21
183
1.16
0.20
4.1
2.2
0.00
0.01
estimate
—
9
69
358
3540
1.07
0.18
6.4
4.8
1.57
1.49
mmol/l
2.57
339
3309
6
80
0.75
0.15
1.2
1.1
—
—
—
0
0
6
80
0.75
0.15
1.2
1.1
—
—
—
0
0
24
258
0.93
0.09
1.0
1.2
—
—
—
0
0
19
175
1.09
0.08
2.1
1.6
—
—
—
0
0
12
107
1.13
0.08
1.4
1.3
—
—
—
0
0
16
146
1.10
0.08
1.4
1.7
—
—
—
0
0
6
75
0.80
0.07
2.0
1.9
—
—
—
0
0
10
112
0.89
0.07
1.4
1.6
—
—
—
0
0
20
187
1.07
0.06
2.0
1.6
—
—
—
0
0
10
110
0.91
0.05
1.4
1.5
—
—
—
0
0
44
426
1.04
0.05
1.7
1.8
—
—
—
0
0
31
299
1.04
0.04
6.3
2.5
6.14
6.20
ph
0.14
21
192
12
128
0.94
0.02
3.8
1.8
—
—
—
0
0
360
3608
0.99
0.01
7.2
5.5
2.66
2.75
mmol/l
1.25
339
3384
40
406
0.98
0.00
1.7
1.4
—
—
—
0
0
23
228
1.01
0.00
1.7
1.8
—
—
—
0
0
19
189
1.01
0.00
2.1
1.6
—
—
—
0
0
49
485
1.01
0.00
1.7
1.8
—
—
—
0
0
47
466
1.01
0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
6.06
—
0
5
19
190
1.00
-0.00
2.1
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
19
190
1.00
-0.00
2.1
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: E4_PRIMARY_ADRENOCORTICAL_INSUFFICIENCY – Primary adrenocortical insufficiency

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).