Benign neoplasm: Nasopharynx

CD2_BENIGN_NASOPHARYNX

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D10.6&
  • Hospital discharge: ICD-9 2107
  • Hospital discharge: ICD-8 2107
  • Cause of death: ICD-10 D10.6&
  • Cause of death: ICD-9 2107
  • Cause of death: ICD-8 2107

2 out of 7 registries used, show all original rules.

354

4. Check minimum number of events

None

354

5. Include endpoints

None

354

6. Filter based on genotype QC (FinnGen only)

316

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10
Name in latin
Neoplasma benignum nasopharyngis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1716 784 921
Only index persons 1545 733 812
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.03
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 52.07 54.78 49.75
Only index persons 51.34 54.20 48.77

-FinnGen-

Key figures

All Female Male
Number of individuals 316 163 153
Unadjusted period prevalence (%) 0.06 0.06 0.07
Median age at first event (years) 57.01 55.38 58.73

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
333
Matched controls
3330
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D10.6
ICD-10 Finland
Benign neoplasm: Nasopharynx
4503599627370496.0
307.7
302
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
12.4
93.1
110
127
EMA30
NOMESCO Finland
Biopsy of rhinopharynx
283.6
69.1
68
*
EMB30
NOMESCO Finland
Adenotomy
20.7
47.2
37
20
UDQ12
NOMESCO Finland
Flexible laryngoscopy
5.9
26.0
51
99
DHA10
NOMESCO Finland
Biopsy of cavity of nose
33.8
21.9
28
9
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
8.1
18.1
25
33
21070
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Nasopharynx
+∞
17.9
17
*
2107A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Nasopharynx
+∞
16.8
16
*
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
19.5
14.9
22
12
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.7
14.8
24
38
H65.2
ICD-10 Finland
Chronic serous otitis media
16.4
14.6
23
15
J35.2
ICD-10 Finland
Hypertrophy of adenoids
12.8
13.8
24
20
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
13.7
115
572
ENA10
NOMESCO Finland
Biopsy of pharynx
52.2
12.9
15
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
5.5
12.7
25
48
R01AD09
ATC
mometasone; nasal
2.2
11.9
174
1090
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
11.5
198
1317
UDC00
NOMESCO Finland
Ear microscopy
3.3
10.9
44
147
1290
FHL
Epipharyngoscopy
+∞
10.5
10
*
C11.9
ICD-10 Finland
Malignant neoplasm: Nasopharynx, unspecified
+∞
10.5
10
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.3
10.2
40
131
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
9.6
10.2
20
22
R01BA52
ATC
pseudoephedrine, combinations; oral
2.2
10.0
114
636
ENB00
NOMESCO Finland
Excision or exploration of lesion of pharynx
102.8
9.5
10
*
EMB10
NOMESCO Finland
Tonsillectomy
4.4
9.3
24
58
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
19.3
9.0
13
7
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.8
8.9
49
195
R01AD08
ATC
fluticasone; nasal
2.1
8.6
108
619
J33.0
ICD-10 Finland
Polyp of nasal cavity
4.7
8.5
20
45
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.4
8.4
64
299
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
34.3
8.1
10
*
J39.2
ICD-10 Finland
Other diseases of pharynx
10.4
8.1
15
15
J34.2
ICD-10 Finland
Deviated nasal septum
3.3
7.9
31
101
H92.0
ICD-10 Finland
Otalgia
3.3
7.9
31
101
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
15.5
7.8
12
8
DHB10
NOMESCO Finland
Excision of lesion of internal nose
46.1
7.7
9
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.1
7.6
21
54
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.5
7.5
49
212
C11.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of nasopharynx
+∞
7.3
7
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
7.2
90
510
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.3
7.2
28
91
H66.9
ICD-10 Finland
Otitis media, unspecified
3.0
7.2
32
113
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.1
7.2
30
102
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
7.1
87
491
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
7.0
132
860
GD1AD
NOMESCO Finland
Thorax CT examination
2.9
7.0
33
120
J01CA04
ATC
amoxicillin; systemic
2.2
7.0
275
2277
R04.0
ICD-10 Finland
Epistaxis
2.7
6.7
37
147
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
6.5
176
1275
J02AC01
ATC
fluconazole; systemic
1.8
6.3
127
839
Z2221
NOMESCO Finland
Medical doctor
1.9
6.3
101
621
8010/3-C11.9
ICD-O-3
Carcinoma, NOS, of nasopharynx, NOS
+∞
6.3
6
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
6.3
102
631
UDM02
NOMESCO Finland
Sinoscopy
5.5
6.2
17
32
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
8.8
6.1
12
14
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.6
6.1
35
142

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
69
272
2.94
12.92
1.6
1.4
—
—
—
0
0
180
1131
2.29
12.32
2.7
2.2
—
—
—
0
0
162
1018
2.15
10.59
8.7
6.2
—
—
—
0
0
232
1695
2.22
10.04
11.5
10.4
4.17
4.15
e9/l
0.05
189
1485
201
1403
2.09
9.62
9.0
6.5
0.72
0.66
%
0.85
185
1309
202
1413
2.09
9.61
8.4
6.4
57.75
58.00
%
0.12
189
1346
201
1409
2.08
9.44
8.8
6.4
2.85
2.81
%
0.11
184
1317
201
1411
2.07
9.38
9.2
6.5
9.00
8.83
%
0.36
185
1324
203
1439
2.05
9.11
8.8
6.5
27.52
27.00
%
0.28
190
1360
215
1575
2.03
8.58
8.8
6.8
0.20
0.19
e9/l
0.41
183
1377
211
1565
1.95
7.77
8.2
6.4
1.81
1.89
e9/l
0.49
183
1385
207
1538
1.91
7.44
8.1
6.4
0.04
0.04
e9/l
0.28
175
1317
206
1532
1.90
7.34
8.2
6.4
0.60
0.59
e9/l
0.22
174
1314
188
1382
1.83
6.70
6.8
6.6
1.22
1.21
mmol/l
0.18
177
1285
200
1524
1.78
6.07
8.3
7.3
1.22
1.21
mmol/l
0.17
175
1315
44
206
2.31
5.66
1.2
1.4
—
—
—
0
0
78
455
1.93
5.66
2.0
2.0
—
—
—
0
0
16
32
5.20
5.64
1.4
1.0
—
—
—
0
0
81
495
1.84
5.05
2.2
2.3
2.28
2.30
g/l
0.19
75
451
63
358
1.94
4.90
2.7
1.7
—
—
—
0
0
186
1440
1.66
4.88
17.9
13.9
1.27
1.25
inr
0.23
152
1202
124
869
1.68
4.76
4.3
4.4
—
—
—
0
0
52
289
1.95
4.30
2.1
2.1
334.39
375.35
nmol/l
0.71
46
266
80
511
1.74
4.25
4.6
3.4
0.82
0.81
mmol/l
0.08
75
484
91
604
1.70
4.21
5.9
4.0
734.75
339.15
ng/l
0.53
69
478
214
1753
1.62
4.19
6.3
5.2
6.86
6.73
mmol/l
0.42
205
1666
169
1310
1.59
4.18
5.7
4.9
35.48
35.51
g/l
0.03
159
1236
171
1338
1.57
4.00
2.5
2.2
96.58
96.23
pmol/l
0.03
90
694
129
947
1.59
3.97
4.1
4.2
7.40
7.40
ph
0.22
98
691
25
111
2.35
3.65
1.2
1.3
—
—
—
0
0
80
533
1.66
3.60
2.2
2.4
11.89
12.97
umol/l
0.75
74
492
71
464
1.67
3.43
2.2
2.4
19.89
22.41
%
1.11
65
431
108
785
1.56
3.37
2.5
2.2
2.61
3.01
mg/l
1.05
91
679
12
33
3.73
3.32
1.1
1.4
—
—
nmol/l
—
0
0
59
370
1.72
3.31
2.3
2.9
1.78
1.79
%
0.01
51
333
60
382
1.70
3.19
1.6
1.3
—
—
—
0
0
228
1956
1.53
3.16
6.8
4.7
—
1.61
—
0
5
14
50
2.88
3.12
1.0
1.2
—
—
—
0
0
166
1342
1.47
3.04
3.4
2.9
119.42
125.58
ug/l
0.13
155
1236
18
75
2.48
3.02
2.8
3.5
1.57
2.44
index
—
7
48
31
163
1.99
3.02
1.1
1.1
—
—
—
0
0
39
222
1.86
3.02
1.8
1.8
1.73
1.42
g/l
0.31
34
201
53
331
1.72
3.02
1.4
1.5
—
—
—
0
0
248
2178
1.54
2.98
5.3
4.3
14.91
14.80
pmol/l
0.26
228
1977
17
70
2.51
2.93
2.5
3.3
61.64
61.27
%
0.02
17
70
162
1314
1.45
2.86
2.7
2.5
77.54
76.41
nmol/l
0.18
145
1168
48
296
1.73
2.86
2.4
3.1
69.48
70.15
e9/l
0.06
36
225
10
28
3.65
2.80
1.9
1.4
—
—
—
0
0
11
34
3.31
2.75
1.3
1.1
—
—
—
0
0
105
791
1.48
2.69
3.9
3.0
321.70
347.43
umol/l
2.08
97
693
12
43
2.86
2.67
1.1
1.5
0.43
46.49
nmol/l
0.49
12
37
75
527
1.55
2.66
1.7
1.7
1036.99
1238.82
nmol/l
1.04
55
396
17
74
2.37
2.62
1.6
1.7
—
—
—
0
0
90
660
1.50
2.62
1.8
1.8
1.06
1.42
mg/l
1.19
75
520
43
264
1.72
2.61
8.5
9.2
—
—
—
0
0
59
394
1.60
2.60
1.3
1.2
—
—
—
0
0
58
387
1.60
2.57
1.9
1.4
—
—
—
0
0
250
2234
1.48
2.45
11.8
8.5
80.32
81.45
u/l
0.11
241
2119
66
460
1.54
2.43
1.7
1.9
—
—
—
0
0
77
555
1.50
2.42
1.4
1.4
33.97
33.63
iu/ml
0.01
26
184
37
223
1.74
2.40
2.0
2.5
—
—
—
0
0
126
1001
1.42
2.39
2.9
2.3
—
—
—
0
0
60
411
1.56
2.38
1.6
1.6
—
—
—
0
0
41
256
1.69
2.35
3.6
2.1
0.00
0.06
estimate
—
6
53
18
85
2.18
2.33
1.2
1.3
—
—
—
0
0
10
34
3.00
2.30
1.5
1.1
—
—
—
0
0
26
143
1.89
2.26
1.2
1.3
—
—
—
0
0
85
639
1.44
2.15
2.0
1.5
2.20
2.59
g/l
1.36
51
375
10
36
2.83
2.15
1.3
1.2
—
—
—
0
0
48
321
1.58
2.11
3.7
3.8
7.38
7.39
ph
0.68
26
195
11
43
2.61
2.10
2.3
3.4
—
—
—
0
0
44
289
1.60
2.09
1.7
1.5
—
—
—
0
0
163
1377
1.36
2.06
3.1
2.8
—
—
estimate
—
0
0
6
15
4.05
2.05
1.5
2.2
—
—
—
0
0
11
44
2.55
2.03
1.0
1.1
—
26.20
—
0
10
43
283
1.60
2.03
4.8
4.0
7.39
7.35
ph
0.91
30
201
59
419
1.50
1.99
4.8
5.0
1.00
1.04
mmol/l
0.53
54
391
51
351
1.53
1.99
9.0
8.3
1.45
1.02
mmol/l
0.38
42
299
111
888
1.38
1.96
8.6
6.4
—
—
—
0
0
6
16
3.80
1.94
1.7
1.1
—
—
—
0
0
50
345
1.53
1.93
2.3
2.3
114.35
118.11
ug/g
0.04
43
275
60
431
1.48
1.92
1.5
1.4
458.18
504.80
titre
0.07
11
100
158
1339
1.34
1.91
13.3
12.1
0.00
0.00
e9/l
0.66
125
1102
21
115
1.88
1.87
2.0
2.1
142.30
364.50
ug/l
2.11
21
107
8
28
2.90
1.87
1.9
1.8
22.20
19.09
ng/l
—
8
28
113
913
1.36
1.86
3.7
3.3
—
—
—
0
0
9
35
2.61
1.81
4.1
3.4
—
—
—
0
0
13
61
2.18
1.74
2.0
1.6
—
—
—
0
0
64
475
1.43
1.73
3.3
3.2
3.29
1.95
e6/l
0.38
35
238
11
48
2.34
1.72
3.0
2.1
—
—
—
0
0
106
857
1.35
1.72
3.7
3.2
0.36
0.45
e6/l
0.22
76
628
5
13
3.89
1.72
1.4
5.1
16.52
50.58
mu/l
—
5
13
50
355
1.48
1.70
9.2
8.3
7.43
7.42
ph
0.25
28
205
126
1047
1.33
1.70
4.0
3.4
2.37
2.36
mmol/l
0.57
111
945
7
25
2.84
1.66
1.1
3.9
12.40
12.15
%
—
7
25
116
961
1.32
1.58
2.9
2.7
58.75
64.88
u/l
0.38
106
892
59
440
1.41
1.56
7.5
7.3
104.49
104.09
mmol/l
0.24
59
440
109
897
1.32
1.55
2.0
1.7
20.92
21.01
nmol/l
0.02
90
741
28
178
1.63
1.54
2.4
2.5
27.94
17.26
au/ml
—
5
11
28
178
1.63
1.54
2.8
3.8
24.37
24.09
mmol/l
0.14
28
178
67
512
1.39
1.54
1.4
1.3
32.37
13.21
u/ml
0.50
14
199
28
179
1.62
1.51
5.3
4.4
—
—
—
0
0
292
2767
1.45
1.42
25.4
16.9
21.88
24.32
mg/l
0.71
261
2305
211
1911
1.28
1.39
4.0
3.6
45.42
52.42
u/l
0.54
202
1807
5
17
2.97
1.36
1.0
1.2
—
—
—
0
0
84
679
1.32
1.34
5.1
4.0
—
0.25
—
0
8
11
54
2.07
1.34
1.7
1.3
—
—
—
0
0
20
121
1.69
1.34
4.6
3.1
25.16
24.78
mmol/l
0.34
20
114
34
235
1.50
1.33
2.7
3.7
81.86
84.22
ng/l
0.06
29
207
15
83
1.85
1.33
1.3
1.2
—
—
—
0
0
38
273
1.44
1.24
2.9
3.2
4.54
4.45
kpa
0.11
38
265
76
613
1.31
1.23
3.4
3.0
2.47
2.46
mmol/l
0.61
67
554
10
49
2.07
1.23
4.8
3.3
0.78
0.89
nmol/l
—
10
43
0
35
0.00
1.16
0.0
1.2
—
—
—
0
0
31
218
1.47
1.14
5.1
2.8
5.28
5.17
kpa
0.33
31
213
84
694
1.28
1.14
1.4
1.3
0.81
1.47
u/ml
0.98
16
180
7
30
2.36
1.13
1.0
1.0
—
—
—
0
0
16
96
1.70
1.12
1.4
1.7
40.25
40.36
nmol/l
0.01
16
91
124
1078
1.24
1.09
5.0
3.7
—
1.00
—
0
5
136
1197
1.23
1.06
4.6
4.0
31.36
87.21
ng/l
0.66
100
895
7
33
2.14
1.06
4.3
2.8
—
—
—
0
0
9
46
1.98
1.04
1.3
2.2
32.11
33.22
pg
—
9
46
23
156
1.51
1.01
4.8
2.8
—
—
—
0
0
45
348
1.34
0.99
1.3
1.3
—
—
—
0
0
0
29
0.00
0.98
0.0
1.3
—
—
—
0
0
26
183
1.46
0.97
1.1
1.2
31.74
130.55
u/ml
—
7
73
13
77
1.72
0.96
2.5
2.4
82.90
71.90
ug/min
—
8
45
14
85
1.68
0.96
1.4
1.2
—
3.29
—
0
11
114
995
1.22
0.95
3.5
3.3
1371.76
1298.07
ng/l
0.09
105
849
7
37
1.91
0.94
1.1
1.3
—
—
—
0
0
272
2590
1.27
0.94
7.1
5.4
1.85
1.96
mu/l
0.75
257
2372
138
1229
1.21
0.94
5.0
3.7
6.34
6.19
ph
0.77
80
691
37
280
1.36
0.93
4.2
4.9
1.16
0.95
%
0.27
19
96
29
211
1.41
0.92
8.2
8.2
23.62
24.85
mmol/l
1.10
29
211
15
95
1.61
0.89
2.2
3.9
1.76
2.74
ratio
—
10
55
76
640
1.24
0.88
1.8
1.8
108621172.95
21627052.96
pmol/l
0.36
58
541
34
258
1.35
0.85
3.8
5.1
0.13
0.12
%
0.04
15
73
6
31
1.95
0.85
1.7
1.7
—
—
—
0
0
282
2707
1.27
0.83
6.0
5.4
6.11
6.01
mmol/l
0.53
259
2475
6
32
1.89
0.82
1.0
1.2
—
—
—
0
0
6
32
1.89
0.82
2.0
1.6
1485.00
1181.11
e6/l
—
6
27
34
261
1.34
0.80
4.5
4.8
0.50
0.56
%
0.11
16
83
77
659
1.22
0.77
5.8
4.3
1.02
1.02
kg/l
0.00
56
432
10
59
1.72
0.76
1.4
1.8
—
—
—
0
0
112
995
1.19
0.76
4.1
3.3
20.99
111.49
e6/l
0.79
83
768
41
327
1.29
0.75
4.8
4.5
3.34
43.28
ug/l
1.01
34
275
290
2801
1.27
0.75
6.5
6.1
2.60
2.67
mmol/l
0.63
265
2586
31
238
1.33
0.74
3.5
2.5
6.20
6.04
ph
0.53
22
155
124
1114
1.18
0.74
4.7
4.0
34.69
78.77
e6/l
1.30
89
801
16
229
0.68
0.73
1.6
1.4
—
—
—
0
0
17
118
1.46
0.71
3.0
1.9
—
—
—
0
0
9
58
1.57
0.70
1.2
1.3
—
—
—
0
0
5
27
1.86
0.68
2.2
1.6
972.20
570.33
e6/l
—
5
21
19
137
1.41
0.66
2.4
2.3
—
—
—
0
0
33
261
1.29
0.65
4.4
5.5
0.07
0.18
%
0.37
15
67
7
44
1.60
0.65
1.0
1.1
—
—
—
0
0
46
380
1.24
0.65
2.9
3.4
4.53
6.53
e9/l
0.69
38
334
277
2674
1.21
0.63
8.2
6.8
40.42
39.75
mmol/mol
0.57
260
2499
8
50
1.61
0.61
1.3
1.7
—
—
—
0
0
8
50
1.61
0.61
1.3
1.7
—
—
—
0
0
8
50
1.61
0.61
1.3
1.7
—
—
—
0
0
8
50
1.61
0.61
1.3
1.7
—
—
—
0
0
5
30
1.68
0.61
1.6
1.4
—
—
—
0
0
8
51
1.58
0.61
1.1
1.1
—
—
—
0
0
18
131
1.40
0.60
2.9
2.8
—
—
—
0
0
292
2837
1.24
0.60
20.9
15.2
—
—
—
0
0
69
601
1.19
0.59
3.4
2.9
514.70
530.31
mosm/kgh2o
0.23
60
525
8
54
1.49
0.57
1.5
1.2
—
—
—
0
0
37
303
1.25
0.57
1.8
1.5
—
—
—
0
0
20
150
1.35
0.57
1.1
1.1
—
—
—
0
0
22
169
1.32
0.55
1.7
1.3
—
—
—
0
0
20
258
0.76
0.52
5.1
3.5
—
—
—
0
0
168
1576
1.13
0.52
5.7
4.1
0.00
0.94
estimate
0.50
20
323
100
1096
0.87
0.50
4.2
3.4
—
—
—
0
0
14
102
1.39
0.48
6.0
2.7
7.41
7.42
ph
0.20
14
102
110
1010
1.13
0.47
4.5
3.5
71.32
55.89
mg/l
0.27
71
662
164
1544
1.12
0.46
5.4
4.0
0.00
0.00
estimate
-0.00
27
340
5
31
1.62
0.43
1.6
3.0
1003.40
829.03
mg
—
5
31
5
31
1.62
0.43
1.8
2.0
—
—
—
0
0
298
2919
1.20
0.43
17.7
12.7
24.81
25.97
u/l
0.71
287
2840
5
32
1.57
0.42
1.2
2.0
—
—
—
0
0
8
58
1.39
0.42
1.3
1.5
—
—
—
0
0
5
33
1.52
0.41
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
80
878
0.88
0.41
4.0
3.4
0.00
0.09
estimate
0.52
22
287
77
698
1.13
0.40
3.5
2.6
4.69
5.03
e6/l
0.09
68
636
8
60
1.34
0.40
1.4
1.1
—
—
—
0
0
5
34
1.48
0.40
1.0
1.1
—
—
—
0
0
88
805
1.13
0.40
1.4
1.4
—
—
—
0
0
14
106
1.33
0.39
4.3
2.9
280.56
234.40
mg/l
—
9
45
112
1041
1.11
0.39
5.6
4.1
15.05
10.07
mg/mmol
0.30
74
660
5
36
1.39
0.38
1.0
1.3
—
—
—
0
0
164
1558
1.10
0.37
5.5
4.0
0.00
4.68
estimate
0.50
27
347
5
37
1.36
0.37
1.4
1.4
—
—
—
0
0
5
37
1.36
0.37
1.4
1.4
1.20
1.22
mm
—
5
27
6
41
1.47
0.36
1.3
1.6
84.43
90.21
%
—
6
41
75
685
1.12
0.35
5.6
5.2
—
—
—
0
0
23
192
1.21
0.33
2.0
2.0
3.37
3.43
mmol/l
0.09
18
146
11
84
1.32
0.30
4.4
5.0
—
—
—
0
0
106
997
1.09
0.29
5.8
5.5
3.65
2.59
ug/l
0.40
94
893
65
600
1.10
0.26
3.8
3.1
0.74
0.82
ug/l
0.28
41
375
112
1063
1.08
0.25
4.5
3.4
7.55
7.64
mmol/l
0.07
92
890
9
76
1.19
0.25
4.7
3.0
56.00
58.54
%
—
9
76
25
218
1.16
0.24
1.8
1.7
—
—
—
0
0
129
1234
1.07
0.23
2.0
2.0
1.41
1.39
mmol/l
0.11
99
1025
304
3004
1.14
0.23
37.3
25.7
4.44
4.49
e12/l
0.79
299
2944
304
3004
1.14
0.23
37.3
25.8
6.82
6.77
e9/l
0.18
298
2943
5
39
1.29
0.23
1.6
1.6
—
—
—
0
0
31
277
1.13
0.22
1.5
1.5
—
—
—
0
0
83
879
0.93
0.22
6.2
4.1
0.00
0.01
estimate
0.50
24
321
0
11
0.00
0.21
0.0
1.1
—
6.36
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
5653.40
—
0
5
0
12
0.00
0.21
0.0
2.5
—
4.16
—
0
12
11
89
1.24
0.21
1.4
1.4
335.00
279.04
ug/g
—
6
54
0
14
0.00
0.20
0.0
1.0
—
62.11
—
0
9
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
53
1.13
0.19
4.7
3.1
3.07
4.41
e9/l
—
6
53
7
61
1.15
0.17
2.0
2.5
7.01
8.92
pmol/l
—
7
61
268
2643
1.07
0.17
4.9
4.5
1.33
1.30
mmol/l
0.25
238
2421
8
72
1.11
0.16
8.5
2.6
4.58
5.04
kpa
—
8
72
8
72
1.11
0.16
8.5
2.6
8.70
8.20
kpa
—
8
72
9
78
1.16
0.15
1.1
1.1
—
—
—
0
0
10
84
1.20
0.14
1.5
1.3
—
—
—
0
0
14
122
1.15
0.14
2.4
1.7
—
—
—
0
0
8
99
0.80
0.14
1.1
2.4
—
—
—
0
0
8
99
0.80
0.14
1.1
2.0
—
—
—
0
0
8
99
0.80
0.14
1.1
2.4
—
—
—
0
0
8
100
0.80
0.14
1.1
2.4
—
—
—
0
0
26
238
1.10
0.13
1.3
1.2
—
—
—
0
0
115
1186
0.95
0.13
5.3
4.0
0.00
0.02
estimate
0.88
22
301
17
152
1.12
0.12
1.4
1.2
—
—
—
0
0
11
95
1.16
0.12
1.1
1.1
1.42
1.55
g/l
0.96
11
95
13
146
0.89
0.10
1.8
1.5
0.24
0.35
mg/l
—
5
61
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
5
63
0.79
0.08
8.6
2.4
—
—
—
0
0
11
98
1.13
0.07
18.8
8.9
—
—
—
0
0
7
82
0.85
0.07
1.0
2.6
—
—
—
0
0
13
118
1.11
0.07
1.3
1.1
—
—
—
0
0
8
94
0.85
0.07
1.0
2.4
—
—
—
0
0
11
99
1.11
0.06
1.1
1.2
0.86
0.90
g/l
0.48
11
99
276
2744
1.03
0.05
5.9
5.3
1.43
1.45
mmol/l
0.42
252
2526
277
2756
1.03
0.04
5.9
5.4
4.52
4.58
mmol/l
0.42
255
2554
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
6
66
0.91
-0.00
1.8
3.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
75
0.93
-0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.02
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
1.79
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
1.08
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
24.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
91.83
—
0
6
5
57
0.88
-0.00
1.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.02
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_NASOPHARYNX and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_NASOPHARYNX 1.468 [1.14, 1.89] 0.003
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 608 females with CD2_BENIGN_NASOPHARYNX died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_NASOPHARYNX 1.524 [1.23, 1.89] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 145 out of 638 males with CD2_BENIGN_NASOPHARYNX died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_NASOPHARYNX.

N-year risk Females Males
1 0.144% 0.226%
5 0.644% 1.578%
10 1.517% 4.198%
15 2.925% 8.015%
20 5.201% 13.646%

Relationships between endpoints

Index endpoint: CD2_BENIGN_NASOPHARYNX – Benign neoplasm: Nasopharynx

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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