auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
492 |
4. Check minimum number of eventsNone |
492 |
5. Include endpointsNone |
492 |
6. Filter based on genotype QC (FinnGen only) |
444 |
Control definitions (FinnGen only)
- Control exclude
- H8_OTHEREAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H93
- Name in latin
- Aliae perceptiones auditoriae abnormes
Similar endpoints
↥List of similar endpoints to
Other abnormal auditory perceptions
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2549 | 1593 | 947 |
| Only index persons | 2466 | 1555 | 911 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 46.50 | 48.98 | 42.40 |
| Only index persons | 46.89 | 49.24 | 42.89 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 444 | 323 | 121 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.06 |
| Median age at first event (years) | 51.74 | 50.76 | 54.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 464
- Matched controls
- 4640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
4503599627370496.0
307.7
463
12
H93.1
ICD-10 Finland
Tinnitus
36.0
206.5
138
54
DFF00
NOMESCO Finland
Pure tone audiometry
26.1
177.7
134
71
Z01.1
ICD-10 Finland
Examination of ears and hearing
14.0
156.5
178
198
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
33.7
151.5
101
38
N07CA01
ATC
betahistine; oral
9.4
58.5
76
95
UDC00
NOMESCO Finland
Ear microscopy
9.0
53.8
72
93
H02
ICPC
Hearing complaint
5.9
50.6
106
221
H91.9
ICD-10 Finland
Hearing loss, unspecified
9.3
35.8
45
53
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
58.9
32.8
38
7
SPAT1043
SPAT
Audiometry
5.5
30.3
63
128
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
165.7
30.0
31
*
H92.0
ICD-10 Finland
Otalgia
5.2
28.0
63
137
H29
ICPC
Ear symptom/complaint other
3.6
22.6
86
277
R42
ICD-10 Finland
Dizziness and giddiness
2.7
19.0
133
603
DFF15
NOMESCO Finland
Speech audiometry
18.5
18.5
28
16
Z3229
NOMESCO Finland
Other healthcare associate professional
3.8
16.0
52
149
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
7.1
15.0
23
34
Z97.4
ICD-10 Finland
Presence of external hearing-aid
26.0
14.8
20
8
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
44.0
14.2
17
*
H01
ICPC
Ear pain/earache
2.7
13.7
87
371
DAX08
NOMESCO Finland
Fitting of hearing aid
23.3
13.0
18
8
R51.80
ICD-10 Finland
Headache
2.4
13.0
106
508
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
+∞
12.6
12
*
G44.2
ICD-10 Finland
Tension-type headache
2.4
12.3
96
450
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
38.7
12.3
15
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
12.2
210
1345
R01AD09
ATC
mometasone; nasal
2.0
12.2
246
1667
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
11.5
201
1290
H03
ICPC
Tinnitus, ringing/buzzing ear
5.4
11.2
22
42
H66.9
ICD-10 Finland
Otitis media, unspecified
3.0
11.0
50
177
A11
ICPC
Chest pain NOS
3.0
11.0
52
189
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
28.8
10.8
14
5
H13
ICPC
Plugged feeling ear
2.3
10.4
93
460
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.9
10.2
51
191
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
9.8
285
2124
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
8.7
9.7
20
24
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.5
9.6
66
290
R5120
NOMESCO Finland
Preparation of an aid
9.4
9.6
19
21
R52.9
ICD-10 Finland
Pain, unspecified
2.5
9.6
65
284
M01AH01
ATC
celecoxib; oral
2.2
9.6
87
433
A02BC05
ATC
esomeprazole; systemic
1.9
9.5
196
1307
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.7
9.4
52
205
L01
ICPC
Neck symptom/complaint
2.1
9.3
96
503
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
9.2
65
289
K07.60
ICD-10 Finland
Snapping jaw
2.9
8.6
42
155
P06
ICPC
Sleep disturbance
2.2
8.6
79
394
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
8.4
38
134
R01AD08
ATC
fluticasone; nasal
1.9
8.4
149
940
SPAT1081
SPAT
Cardiorespiratory global assessment
3.8
8.3
25
68
D06
ICPC
Abdominal pain localized other
2.5
8.1
53
228
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.0
8.0
35
121
A27
ICPC
Fear of other disease NOS
3.2
8.0
32
105
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.8
8.0
24
65
R03DC03
ATC
montelukast; oral
2.0
7.9
94
516
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.4
7.9
56
249
R06AE07
ATC
cetirizine; oral
1.7
7.9
218
1562
C07AA05
ATC
propranolol; systemic
1.9
7.7
113
667
F45.8
ICD-10 Finland
Other somatoform disorders
2.6
7.7
47
195
N05BA04
ATC
oxazepam; oral
1.8
7.7
134
838
H81.0
ICD-10 Finland
Ménière disease
7.3
7.5
17
24
R53
ICD-10 Finland
Malaise and fatigue
1.8
7.5
131
817
Z2445
NOMESCO Finland
Psychologist
2.9
7.5
35
126
L17
ICPC
Foot/toe symptom/complaint
1.8
7.5
155
1019
S29
ICPC
Skin symptom/complaint other
1.9
7.5
105
611
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
7.3
130
816
A02BC02
ATC
pantoprazole; systemic
1.8
7.3
310
2482
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.6
7.2
17
38
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
7.2
181
1254
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
30.5
7.2
9
*
L13
ICPC
Hip symptom/complaint
1.9
7.2
97
557
H02AB06
ATC
prednisolone; systemic
1.7
7.2
216
1573
R01AD12
ATC
fluticasone furoate; nasal
1.7
7.1
166
1127
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
7.1
92
521
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
7.0
131
832
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
7.0
126
791
R02
ICPC
Shortness of breath/dyspnoea
2.1
7.0
67
339
M79.6
ICD-10 Finland
Pain in limb
1.7
7.0
219
1608
A01
ICPC
Pain general/multiple sites
2.2
6.9
59
285
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
6.9
74
391
D02
ICPC
Abdominal pain epigastric
2.7
6.9
38
150
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.1
6.8
67
342
Z01.2
ICD-10 Finland
Dental examination
1.7
6.7
235
1770
C05AA08
ATC
fluocortolone; rectal, topical
2.1
6.7
63
317
R49.01
ICD-10 Finland
Functional dysphonia
3.6
6.6
22
64
L19
ICPC
Muscle symptom/complaint NOS
3.9
6.6
19
50
N06AX22
ATC
agomelatine; oral
3.9
6.6
19
50
Z71.9
ICD-10 Finland
Counselling, unspecified
2.4
6.6
47
210
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.7
6.5
34
130
N05CD07
ATC
temazepam; oral
2.3
6.5
51
238
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.0
6.4
69
365
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.3
6.4
49
226
L08
ICPC
Shoulder symptom/complaint
1.8
6.3
113
706
N01
ICPC
Headache
2.0
6.3
74
403
N17
ICPC
Vertigo/dizziness
2.1
6.3
63
324
D11
ICPC
Diarrhoea
2.0
6.3
71
382
R03AC02
ATC
salbutamol; inhalant
1.6
6.3
268
2110
R4135
NOMESCO Finland
Rehabilitation for hearing problems
+∞
6.3
6
*
SPAT1153
SPAT
Removal of sutures
1.7
6.2
133
875
H91.1
ICD-10 Finland
Presbycusis
6.4
6.2
15
24
D07AB02
ATC
hydrocortisone butyrate; topical
1.7
6.0
139
933
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
73
301
2.69
12.20
2.6
2.4
15.78
18.06
au/ml
—
10
25
68
274
2.74
11.87
1.3
1.3
51.76
35.59
au/ml
—
7
23
379
3063
2.30
11.03
5.3
4.1
9.02
10.88
mm/h
2.72
368
2887
307
2405
1.82
8.31
9.4
9.8
4.03
4.02
e9/l
0.02
271
2087
280
2137
1.78
8.25
3.3
3.0
95.66
92.58
ug/l
0.17
267
2022
258
1928
1.76
8.13
7.5
6.7
1.22
1.21
mmol/l
1.11
235
1680
230
1668
1.75
8.02
2.3
2.0
101.46
97.44
pmol/l
0.64
121
890
292
2273
1.77
7.87
4.8
4.6
6.17
6.51
mmol/l
3.54
273
2133
389
3312
2.08
7.86
5.4
4.6
14.64
14.59
pmol/l
0.13
369
3092
96
549
1.94
7.18
1.7
1.6
1067.37
1179.76
nmol/l
0.66
78
428
430
3850
2.60
7.05
6.8
5.5
1.80
1.83
mu/l
0.35
418
3636
104
621
1.87
6.80
2.2
2.3
14.45
13.41
umol/l
0.80
96
585
247
1888
1.66
6.64
3.0
2.5
76.76
76.07
nmol/l
0.16
237
1731
443
4052
3.06
6.44
18.4
15.2
3.92
3.94
mmol/l
1.23
438
3968
160
1115
1.66
6.02
1.4
1.3
1.65
2.34
u/ml
0.28
45
309
142
962
1.69
5.94
1.8
1.8
0.81
1.16
mg/l
1.20
106
745
441
4066
2.71
5.50
18.1
13.4
18.51
22.00
mg/l
2.13
376
3278
440
4053
2.66
5.49
18.4
15.1
139.96
139.67
mmol/l
2.16
435
3980
123
822
1.68
5.35
1.4
1.3
4.54
12.02
u/ml
1.66
53
335
223
1725
1.56
5.27
7.5
6.1
1.22
1.22
mmol/l
0.27
207
1616
215
1657
1.55
5.12
4.7
4.6
37.22
36.47
g/l
1.21
206
1581
353
3057
1.65
4.95
8.3
7.8
75.51
79.19
u/l
1.11
337
2921
272
2226
1.54
4.82
3.9
3.6
0.00
7.58
estimate
0.80
55
462
274
2250
1.53
4.75
4.0
3.6
0.00
0.01
estimate
0.50
49
436
29
122
2.47
4.66
1.1
1.1
1.55
11.50
eliau/ml
—
6
15
452
4265
3.31
4.52
13.3
11.3
25.63
25.61
u/l
0.01
445
4182
90
581
1.68
4.40
2.2
2.3
2.36
2.38
g/l
0.12
80
543
256
2094
1.50
4.36
5.4
6.4
10.51
10.90
umol/l
0.28
242
2002
69
415
1.78
4.33
2.5
2.2
424.94
383.38
nmol/l
1.25
62
398
13
29
4.58
4.27
2.7
3.2
—
—
—
0
0
139
1005
1.55
4.25
2.4
2.1
2.60
2.90
mg/l
0.81
124
867
124
874
1.57
4.24
1.5
1.3
24.58
33.08
iu/ml
0.46
36
283
266
2202
1.49
4.21
3.9
3.6
0.00
0.00
estimate
0.50
54
461
104
707
1.61
4.13
5.6
3.8
153.89
396.29
ng/l
0.93
72
497
47
254
1.95
4.12
2.2
2.3
14.09
12.47
nmol/l
0.67
42
239
332
2886
1.53
4.07
4.1
3.4
—
—
—
0
0
29
133
2.26
3.88
1.5
1.3
—
—
—
0
0
148
1109
1.49
3.76
4.4
2.9
0.10
0.40
e6/l
4.48
113
790
180
1403
1.46
3.75
3.6
3.3
18.24
82.26
ng/l
0.81
93
900
162
1237
1.48
3.75
2.3
2.5
53.20
66.51
u/l
1.53
152
1167
64
395
1.72
3.68
5.5
7.9
1.45
0.87
mmol/l
0.72
56
329
407
3738
1.72
3.67
6.0
5.7
37.70
38.33
mmol/mol
1.05
388
3551
81
535
1.62
3.60
2.2
2.3
24.70
22.67
%
0.66
75
508
68
430
1.68
3.58
1.8
1.8
—
—
—
0
0
12
32
3.82
3.41
1.0
1.1
—
—
—
0
0
30
148
2.10
3.39
1.4
1.5
6.50
11.10
u/l
2.05
22
120
86
585
1.58
3.38
1.9
2.0
29.93
29.23
s
0.28
86
572
130
967
1.48
3.38
3.2
2.5
318.39
329.94
umol/l
0.71
115
873
7
10
7.08
3.37
1.3
1.0
86.00
94.90
%
—
7
10
133
996
1.47
3.34
2.8
2.1
—
—
—
0
0
177
1399
1.43
3.34
4.2
3.0
—
—
—
0
0
118
867
1.48
3.25
2.7
2.4
3.14
6.83
e6/l
2.84
107
780
17
66
2.64
3.25
1.2
1.3
—
—
—
0
0
10
25
4.06
3.10
1.2
1.4
—
—
—
0
0
94
671
1.50
2.96
4.5
2.8
0.66
0.93
e6/l
0.75
53
338
49
299
1.71
2.95
1.4
1.5
—
—
—
0
0
8
17
4.77
2.93
2.0
1.4
0.51
0.52
e9/l
—
8
17
413
3858
1.64
2.85
5.2
4.6
5.76
5.81
mmol/l
0.33
394
3596
83
586
1.51
2.75
1.8
1.8
—
—
—
0
0
428
4042
1.76
2.74
5.9
5.4
2.81
2.77
mmol/l
0.40
409
3822
132
1022
1.41
2.71
3.9
3.7
96.99
94.33
%
0.76
125
1004
45
276
1.70
2.67
2.3
1.7
—
—
—
0
0
12
43
2.84
2.66
2.3
2.3
22.80
18.66
mg/l
—
5
17
62
414
1.57
2.64
2.5
2.4
29.66
33.76
u/l
0.60
53
349
406
3792
1.57
2.63
4.2
4.0
1.27
1.25
mmol/l
0.22
385
3551
140
1100
1.39
2.63
1.7
1.6
20.73
20.85
nmol/l
0.03
122
949
28
149
1.94
2.62
1.1
1.3
—
1.20
—
0
7
424
4002
1.69
2.61
5.4
4.8
4.76
4.73
mmol/l
0.24
404
3792
5
7
7.21
2.55
1.2
1.4
—
—
—
0
0
18
82
2.24
2.50
1.2
1.3
—
—
—
0
0
29
159
1.88
2.50
1.6
1.7
4.96
9.25
u/ml
—
5
41
86
624
1.46
2.50
4.9
2.8
2.79
2.73
e6/l
0.03
43
290
15
63
2.43
2.48
2.2
2.1
13.60
13.20
%
0.48
15
63
126
986
1.38
2.40
3.3
3.4
1.02
1.02
kg/l
0.47
82
655
101
761
1.42
2.40
1.5
1.7
467.76
37313864.57
pmol/l
1.00
84
670
421
3982
1.62
2.37
5.2
4.7
1.52
1.51
mmol/l
0.12
404
3758
323
2915
1.36
2.35
3.5
3.1
38.35
43.09
u/l
0.72
311
2798
204
1725
1.33
2.33
2.1
1.9
1.25
1.36
mmol/l
1.22
187
1500
124
976
1.37
2.27
1.8
1.6
—
—
—
0
0
21
107
2.01
2.24
1.2
1.3
—
1.10
—
0
6
5
9
5.60
2.22
1.6
1.7
—
—
—
0
0
40
252
1.64
2.18
1.1
1.1
—
—
—
0
0
11
42
2.66
2.15
1.0
1.1
—
—
—
0
0
15
68
2.25
2.13
1.1
1.3
—
—
—
0
0
37
230
1.66
2.12
3.0
3.4
67.09
204.72
ng/l
4.72
37
215
46
305
1.56
2.05
3.1
2.7
74.86
71.33
ml/min/173m2
0.32
21
135
25
141
1.82
2.01
1.2
1.3
—
3.16
—
0
13
24
134
1.83
1.99
1.2
1.1
—
—
—
0
0
24
135
1.82
1.95
1.2
1.1
—
—
—
0
0
7
22
3.21
1.88
4.0
4.3
320.14
696.86
u/ml
—
7
22
122
986
1.32
1.85
3.3
3.3
538.49
972.04
ng/l
3.38
103
840
58
415
1.45
1.83
1.9
1.8
—
—
—
0
0
170
1439
1.29
1.83
3.6
3.1
26.88
30.95
u/l
1.97
162
1373
21
116
1.85
1.81
1.3
1.1
1.36
2.06
u/ml
0.23
13
64
11
47
2.37
1.79
1.0
1.1
—
—
—
0
0
36
234
1.58
1.77
2.4
2.3
4277.04
3949.62
u/l
0.05
11
106
24
142
1.73
1.68
1.2
1.3
—
6.82
—
0
23
222
1959
1.26
1.65
3.1
2.6
—
—
estimate
—
0
0
193
1677
1.26
1.64
3.5
3.4
0.00
0.02
estimate
1.13
43
388
163
1390
1.27
1.62
2.8
3.3
2.36
2.36
mmol/l
0.01
156
1283
8
32
2.53
1.60
1.3
1.2
—
—
—
0
0
18
99
1.85
1.59
1.3
1.6
2.08
15.42
e6/l
1.05
13
71
83
650
1.34
1.56
2.3
2.1
—
—
—
0
0
89
705
1.32
1.55
5.6
4.9
1.46
2.08
ug/l
1.29
82
634
405
3864
1.38
1.51
15.3
13.0
86.64
86.05
ml/min/173m2
0.24
388
3555
18
101
1.81
1.51
1.3
1.6
852.08
1362.24
e6/l
0.14
13
76
26
164
1.62
1.46
2.3
1.6
—
—
—
0
0
14
73
1.95
1.45
1.2
1.2
—
—
—
0
0
143
1215
1.26
1.45
4.1
3.6
0.00
0.00
estimate
0.80
53
436
6
22
2.75
1.44
1.0
1.2
174.72
171.30
pmol/l
—
6
22
6
22
2.75
1.44
1.7
2.2
0.83
1.05
index
—
6
22
65
498
1.35
1.42
5.0
6.3
104.32
104.24
mmol/l
0.05
65
498
10
46
2.20
1.41
1.0
1.1
—
—
—
0
0
21
127
1.68
1.39
1.6
1.3
293.69
307.55
ug/g
0.13
16
79
17
97
1.78
1.36
1.4
1.1
3.40
0.79
u/ml
—
10
51
18
105
1.74
1.35
1.2
1.5
—
—
—
0
0
5
18
2.80
1.29
1.4
3.9
64.40
166.67
nmol/l
—
5
18
28
187
1.53
1.27
1.5
1.4
—
—
—
0
0
14
77
1.84
1.26
1.0
1.1
1.90
2.25
eliau/ml
—
6
35
71
563
1.31
1.24
4.8
4.2
23.15
22.22
%
0.17
23
255
9
45
2.02
1.24
1.0
1.2
—
—
—
0
0
14
78
1.82
1.22
1.9
1.9
182.36
221.77
pmol/l
0.77
14
73
8
37
2.18
1.22
1.1
1.2
—
84.29
—
0
7
18
109
1.68
1.20
1.2
1.1
—
—
—
0
0
15
86
1.77
1.20
1.3
1.3
257.72
228.13
u/ml
—
10
50
6
26
2.32
1.19
1.0
1.4
—
—
—
0
0
41
302
1.39
1.16
1.4
1.4
29.27
25.20
iu/l
0.32
34
261
5
21
2.40
1.09
1.4
1.3
204.20
773.70
u/l
—
5
21
89
747
1.24
1.00
2.5
2.7
2.42
2.44
mmol/l
1.19
83
677
84
703
1.24
0.97
2.5
2.3
—
—
—
0
0
9
50
1.82
0.97
1.0
1.0
—
—
—
0
0
21
141
1.51
0.96
1.5
1.6
0.00
0.04
iu/ml
—
6
19
9
52
1.74
0.93
1.3
1.2
—
—
—
0
0
50
399
1.28
0.87
1.7
1.8
3.47
3.41
mmol/l
0.18
36
287
8
48
1.68
0.79
2.5
4.7
15.89
45.09
u/ml
—
8
48
17
115
1.50
0.78
2.4
2.5
1.78
1.85
index
—
9
60
9
54
1.68
0.75
1.3
1.4
—
—
—
0
0
34
264
1.31
0.74
1.4
1.3
—
—
—
0
0
7
38
1.85
0.74
1.0
1.2
120.00
102.32
pmol/l
—
7
38
54
446
1.24
0.73
5.4
4.4
33.35
32.18
%
0.35
37
297
27
204
1.34
0.70
2.8
2.4
0.91
0.61
%
0.68
27
204
13
192
0.67
0.69
1.2
1.1
0.92
0.88
g/l
0.28
13
192
53
443
1.22
0.65
3.5
2.9
1.22
0.75
ug/l
0.36
34
268
48
398
1.23
0.64
5.9
5.9
—
—
—
0
0
19
138
1.39
0.63
18.4
5.4
24.75
25.34
mmol/l
0.90
19
132
37
298
1.26
0.63
3.6
3.5
4.43
4.67
pmol/l
0.91
32
265
13
187
0.69
0.62
1.2
1.1
1.48
1.59
g/l
0.96
13
187
27
210
1.30
0.60
1.5
1.9
1.10
4.86
iu/ml
—
7
43
11
72
1.54
0.59
1.6
2.7
6.55
6.82
pmol/l
0.09
11
72
6
36
1.68
0.57
2.8
1.2
—
—
—
0
0
6
36
1.68
0.57
2.8
1.2
—
—
—
0
0
46
386
1.21
0.56
4.7
3.7
6.10
5.80
kpa
1.37
46
377
22
168
1.32
0.56
1.5
1.5
—
—
—
0
0
22
169
1.32
0.54
1.5
1.5
1.10
1.22
ratio
0.36
14
108
22
169
1.32
0.54
1.5
1.5
1.00
0.93
ratio
0.36
14
108
22
169
1.32
0.54
1.5
1.5
1.08
1.15
ratio
0.22
14
108
18
134
1.36
0.54
1.7
1.9
—
—
—
0
0
27
214
1.28
0.53
1.6
1.4
—
—
—
0
0
10
66
1.53
0.53
1.1
1.3
—
215.00
—
0
8
9
63
1.44
0.52
1.0
1.7
—
—
—
0
0
19
146
1.31
0.47
1.9
1.6
0.23
0.24
g/l
0.15
19
137
12
85
1.42
0.47
1.7
1.6
—
—
—
0
0
10
68
1.48
0.47
1.1
1.3
—
—
—
0
0
7
48
1.47
0.47
1.0
1.5
—
—
—
0
0
7
48
1.47
0.47
1.0
1.1
—
—
—
0
0
134
1242
1.11
0.45
3.0
3.0
0.00
0.02
estimate
0.96
42
378
32
380
0.83
0.42
3.1
2.8
—
—
—
0
0
21
167
1.27
0.42
1.2
1.3
—
—
—
0
0
10
70
1.44
0.42
1.9
1.8
—
—
—
0
0
14
105
1.34
0.41
1.2
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
16
123
1.31
0.41
1.6
1.3
—
—
—
0
0
19
152
1.26
0.37
1.9
1.6
1.05
1.22
g/l
2.54
19
142
5
37
1.36
0.37
3.0
2.2
—
—
—
0
0
6
43
1.40
0.35
1.5
1.2
—
—
—
0
0
15
189
0.79
0.35
1.4
1.4
190.77
253.07
miu/ml
—
6
104
25
209
1.21
0.34
1.5
1.5
0.22
0.30
mg/l
—
9
87
58
521
1.13
0.34
2.0
2.0
3.68
3.34
ratio
1.22
44
402
6
45
1.34
0.34
1.3
1.2
—
—
—
0
0
6
45
1.34
0.34
1.3
1.2
—
—
—
0
0
6
46
1.31
0.33
1.3
1.2
—
—
—
0
0
7
52
1.35
0.31
1.0
1.3
—
—
—
0
0
16
129
1.25
0.30
2.3
1.7
—
—
—
0
0
13
103
1.27
0.28
2.2
2.6
—
—
—
0
0
23
197
1.18
0.26
1.3
1.5
—
—
—
0
0
5
72
0.69
0.26
2.4
2.9
22.58
51.65
ug/min
—
5
40
9
73
1.24
0.25
1.8
1.3
—
—
—
0
0
44
485
0.90
0.25
2.0
2.5
9.65
7.17
umol/l
0.26
38
428
12
96
1.26
0.24
1.8
1.3
—
—
—
0
0
41
370
1.12
0.24
3.7
4.5
9.07
19.78
ug/l
0.37
32
304
6
83
0.72
0.24
1.0
1.1
—
—
—
0
0
17
143
1.20
0.23
3.4
2.1
5.83
5.03
iu/l
—
6
59
5
39
1.29
0.23
1.4
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
430.00
—
0
6
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.14
—
0
5
0
10
0.00
0.21
0.0
1.0
—
85.50
—
0
10
0
10
0.00
0.21
0.0
1.0
—
0.07
—
0
5
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
5
43
1.16
0.21
1.4
1.2
—
—
—
0
0
5
43
1.16
0.21
1.0
1.3
—
—
—
0
0
138
1324
1.06
0.21
3.3
3.4
8.07
7.73
mmol/l
0.32
117
1134
23
202
1.15
0.20
2.0
1.7
—
—
—
0
0
6
50
1.20
0.20
2.5
1.4
—
—
—
0
0
6
51
1.18
0.19
2.5
1.4
—
—
—
0
0
6
51
1.18
0.19
2.5
1.4
—
—
—
0
0
6
52
1.16
0.19
2.5
1.4
—
—
—
0
0
6
52
1.16
0.19
2.5
1.4
—
—
—
0
0
6
52
1.16
0.19
2.5
1.4
—
—
—
0
0
124
1191
1.06
0.18
3.8
4.1
2.76
8.68
mg/mmol
3.73
66
716
45
417
1.09
0.17
2.3
2.1
—
—
—
0
0
9
78
1.16
0.15
2.2
1.4
—
—
—
0
0
9
78
1.16
0.15
2.2
1.4
—
—
—
0
0
7
89
0.78
0.14
1.1
1.9
—
—
—
0
0
23
208
1.11
0.14
1.6
2.0
2.19
2.69
mg/l
0.37
16
156
10
117
0.85
0.13
1.1
1.2
—
—
—
0
0
10
85
1.18
0.12
1.9
1.5
—
—
—
0
0
5
44
1.14
0.10
4.0
1.7
—
—
—
0
0
5
46
1.09
0.09
1.8
2.7
1.25
1.19
mmol/l
—
5
46
5
46
1.09
0.09
1.8
2.7
107.20
105.61
mmol/l
—
5
46
27
253
1.07
0.08
13.8
4.1
5.10
5.16
kpa
0.19
27
245
36
343
1.05
0.07
2.1
1.9
—
—
—
0
0
33
315
1.05
0.06
1.5
1.5
1118.11
1006.19
mu/l
0.37
27
266
9
104
0.86
0.06
4.3
3.6
28.93
89.99
mg/l
—
9
88
9
104
0.86
0.06
4.3
3.6
35.40
32.02
mg/l
—
9
86
10
111
0.90
0.06
1.6
1.5
43.59
54.12
ug/l
—
10
111
38
366
1.04
0.05
1.2
1.2
80.82
171.43
u/ml
1.72
11
159
18
169
1.07
0.05
1.4
1.5
—
—
—
0
0
12
129
0.93
0.03
5.2
4.7
1.16
1.29
mg/l
0.70
12
119
89
878
1.02
0.03
1.7
1.5
—
—
—
0
0
14
132
1.06
0.02
2.2
1.7
—
—
—
0
0
17
165
1.03
0.00
3.2
3.2
25.69
25.19
mmol/l
0.42
17
160
17
167
1.02
0.00
1.2
1.9
—
—
—
0
0
6
61
0.98
0.00
1.0
1.1
—
16.56
—
0
16
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
5
56
0.89
-0.00
1.2
1.4
284.40
410.90
pmol/l
—
5
49
15
150
1.00
-0.00
1.4
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
82
0.98
-0.00
1.4
1.3
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
5.86
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_ABNAUDPER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_ABNAUDPER | 0.748 [0.58, 0.96] | 0.025 |
| Birth year | 0.998 [0.99, 1.01] | 0.628 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 1328 females with H8_ABNAUDPER died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have H8_ABNAUDPER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.074% | No data |
| 5 | 0.432% | No data |
| 10 | 1.122% | No data |
| 15 | 2.294% | No data |
| 20 | 4.246% | No data |
Relationships between endpoints
↥Index endpoint: H8_ABNAUDPER – Other abnormal auditory perceptions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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