Colitis, primary sclerosing, strict definition

K11_PSC_COLITIS_STRICT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • K11_CHOLANGI
2969

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

443

6. Filter based on genotype QC (FinnGen only)

410

Control definitions (FinnGen only)

Control conditions
not K11_CHOLANGI

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF3

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1356 487 865
Only index persons 1293 469 824
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 36.00 36.74 35.48
Only index persons 35.04 36.02 34.48

-FinnGen-

Key figures

All Female Male
Number of individuals 410 189 221
Unadjusted period prevalence (%) 0.09 0.07 0.10
Median age at first event (years) 37.71 37.72 37.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
416
Matched controls
4160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K51.5
ICD-10 Finland
Left sided colitis
15284.5
307.7
415
59
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
216.0
307.7
303
51
A05AA02
ATC
ursodeoxycholic acid; oral
1417.8
307.7
363
20
UJF30
NOMESCO Finland
Ileoscopy through colon
41.0
307.7
282
203
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
856.5
307.7
396
94
A07EC02
ATC
mesalazine; oral, rectal
540.5
307.7
389
108
K83.0
ICD-10 Finland
Cholangitis
+∞
307.7
414
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
50.9
307.7
307
218
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
1074.2
307.7
282
8
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
181.8
307.2
151
13
K51.8
ICD-10 Finland
Other ulcerative colitis
100.4
303.3
161
26
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
174.3
298.0
147
13
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
81.4
297.1
164
33
L04AX01
ATC
azathioprine; systemic
50.1
297.1
189
68
UJK02
NOMESCO Finland
ERCP
91.8
290.1
156
27
UJF32
NOMESCO Finland
Coloscopy
37.0
277.1
348
506
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
86.3
276.5
150
27
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
77.6
254.0
140
27
A07EA06
ATC
budesonide; oral, local oral
39.0
248.1
168
71
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
23.9
239.0
222
190
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
52.3
201.3
120
32
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
120.9
197.7
101
11
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
96.8
173.3
91
12
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
39.1
154.9
99
33
WX404
NOMESCO Finland
Intravenous generell anesthesy
10.8
136.9
246
491
K51
ICD-10 Finland
Ulcerative colitis
57.9
132.9
76
16
A07EA02
ATC
hydrocortisone; rectal
31.6
132.1
90
36
K83.1
ICD-10 Finland
Obstruction of bile duct
63.0
129.9
73
14
WX402
NOMESCO Finland
General anaesthesia
10.3
129.9
258
571
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
56.0
128.5
74
16
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
8.6
109.1
252
633
K50.8
ICD-10 Finland
Other Crohn disease
33.5
106.1
70
25
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
58.3
105.4
60
12
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.7
95.6
158
273
UJK12
NOMESCO Finland
Peroral cholangioscopy
+∞
95.6
88
*
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
56.3
94.3
54
11
127
Kela drug reimbursment
Transplant complication
35.3
89.9
58
19
L01BB02
ATC
mercaptopurine; oral
27.8
88.5
62
26
K50.9
ICD-10 Finland
Crohn disease, unspecified
26.8
87.3
62
27
J01MA12
ATC
levofloxacin; systemic
7.4
86.1
172
360
K50.1
ICD-10 Finland
Crohn disease of large intestine
35.1
85.2
55
18
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.7
84.3
229
643
ZXE00
NOMESCO Finland
One hour or less
7.0
81.5
289
1025
P01AB01
ATC
metronidazole; oral, rectal
7.1
81.1
296
1076
ZX120
NOMESCO Finland
Intravenous
9.4
80.9
113
158
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
9.7
75.6
101
133
K76.9
ICD-10 Finland
Liver disease, unspecified
28.2
75.0
52
21
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
121.5
74.9
79
8
H02AB07
ATC
prednisone; oral
7.3
71.4
130
243
TPH04
NOMESCO Finland
Cathetrisation of vein
6.0
71.2
186
492
L04AD01
ATC
ciclosporin; systemic
25.1
70.5
51
23
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
24.1
69.3
51
24
ZXD10
NOMESCO Finland
Scheduled procedure
5.7
68.5
257
920
WX002
NOMESCO Finland
Sedation and analgesia
6.2
68.3
161
386
H02AB06
ATC
prednisolone; systemic
6.0
64.7
305
1300
L04AA06
ATC
mycophenolic acid; systemic
20.9
64.0
50
27
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
+∞
63.2
59
*
L04AD02
ATC
tacrolimus; systemic
31.0
62.9
42
15
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
22.4
60.8
46
23
J01MA02
ATC
ciprofloxacin; systemic
5.1
59.2
253
976
WX302
NOMESCO Finland
Thoracal epidural anesthesy
11.1
58.5
67
71
Z94.4
ICD-10 Finland
Liver transplant status
139.8
57.5
60
5
Z2221
NOMESCO Finland
Medical doctor
4.8
56.0
208
713
JJC00
NOMESCO Finland
Allogenic transplantation of liver
316.4
55.6
55
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
22.1
55.4
42
21
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
8.7
55.4
78
108
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
157.9
53.2
55
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.7
52.4
123
287
A07EC01
ATC
sulfasalazine; oral, rectal
7.3
52.3
87
145
JN4CD
NOMESCO Finland
Very extensive body CT
15.1
50.1
46
34
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.4
48.6
69
96
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
499.9
46.2
45
*
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
18.4
45.0
37
22
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
251.5
44.9
45
*
K74.3
ICD-10 Finland
Primary biliary cirrhosis
132.1
44.8
47
*
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
167.7
43.7
45
*
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
11.0
43.6
49
50
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
14.1
43.2
41
32
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
9.5
43.1
54
64
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
163.5
42.7
44
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
163.5
42.7
44
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
6.0
42.0
85
171
WVA20
NOMESCO Finland
Medicine administration
10.7
41.1
47
49
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
437.9
40.8
40
*
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
151.2
39.5
41
*
R50.9
ICD-10 Finland
Fever, unspecified
4.3
38.0
127
386
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
88.4
36.5
40
5
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
+∞
36.0
34
*
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
47.8
35.7
43
10
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
10.7
35.3
40
41
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.8
34.8
46
58
UJF92
NOMESCO Finland
Capsular endoscopy
13.7
34.4
33
26
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
14.4
34.3
32
24
H02AB04
ATC
methylprednisolone; systemic
4.6
34.3
98
263
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
9.0
34.0
44
54
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
7.0
33.0
54
87
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
31.4
239
1210
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
172.8
31.1
32
*
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
30.6
29
*
TPH07
NOMESCO Finland
Cathetrisation of artery
4.8
30.5
79
195
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
30.0
155
620
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
54.4
29.9
35
7
C10AC01
ATC
colestyramine; oral
10.0
29.6
35
38
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.7
28.5
57
112
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
28.5
27
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.9
28.4
101
315
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
9.5
28.4
35
40
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
155.4
28.0
29
*
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
51.0
27.9
33
7
L04AB04
ATC
adalimumab; parenteral
8.9
27.8
36
44
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
39.6
26.6
33
9
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
+∞
26.3
25
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.5
26.2
45
76
JJ5AT, ,
NOMESCO Finland
276.9
26.0
26
*
JAH00
NOMESCO Finland
Laparotomy
9.8
25.9
31
34
253, ,
Kela drug reimbursment
96.1
25.0
27
*
3042, ,
Kela drug reimbursment
96.1
25.0
27
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
46.1
24.9
30
7
N02AX02
ATC
tramadol; systemic, rectal
2.9
24.8
215
1127
A07EA01
ATC
prednisolone; oral, rectal
40.2
24.3
30
8
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.9
24.1
46
86
L04AC05
ATC
ustekinumab; parenteral
49.8
23.6
28
6
ZXE40
NOMESCO Finland
More than seven and less than nine hours
8.9
23.4
30
36
D94
ICPC
Chronic enteritis/ulcerative colitis
38.8
23.3
29
8
L04AA01
ATC
[U] ciclosporin
37.4
22.3
28
8
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.7
22.0
43
82
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
23.8
22.0
31
14
3AC01, ,
NOMESCO Finland
41.1
22.0
27
7
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
84.8
21.9
24
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.4
21.7
60
154
A07DA03
ATC
loperamide; oral
8.8
21.6
28
34
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.9
21.5
70
203
H02AB09
ATC
hydrocortisone; systemic
8.0
21.5
30
40
UJF02
NOMESCO Finland
Peroral enteroscopy
39.5
21.0
26
7
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
220.6
20.8
21
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
21.5
20.7
30
15
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
23.9
20.7
29
13
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.9
20.2
65
187
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
20.2
201
1100
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
37.9
20.1
25
7
A07AA11
ATC
rifaximin; oral
209.6
19.7
20
*
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
27.6
19.4
26
10
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
40.5
18.7
23
6
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.9
18.6
110
460
K85.8
ICD-10 Finland
Other acute pancreatitis
22.1
17.5
25
12
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
4.4
17.2
46
115
A07AA09
ATC
vancomycin; oral
23.1
17.1
24
11
WX419
NOMESCO Finland
Other general anesthesy
16.0
16.9
27
18
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
16.8
16
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.3
16.6
46
118
R4110
NOMESCO Finland
Physiotherapy
2.5
16.2
139
694
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.6
16.1
122
575
JN4AD
NOMESCO Finland
Body CT examination
3.4
16.0
62
201
K83
ICD-10 Finland
Other diseases of biliary tract
+∞
15.7
15
*
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
88.5
15.7
17
*
1370
FHL
Colonoscopy, whole colon
39.7
15.5
19
5
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.8
15.5
36
80
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.3
15.4
23
33
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
15.1
72
265
A02BC02
ATC
pantoprazole; systemic
2.4
14.4
293
2084
JFF10
NOMESCO Finland
Loop enterostomy
28.3
14.4
19
7
Z93.2
ICD-10 Finland
Ileostomy status
44.1
14.2
17
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
14.0
80
325
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
24.8
13.9
19
8
B01AB05
ATC
enoxaparin; parenteral
2.4
13.9
131
676
K92.1
ICD-10 Finland
Melaena
4.7
13.8
33
75
WZC00
NOMESCO Finland
Treatment plan or consultation
2.2
13.8
180
1064
256, ,
Kela drug reimbursment
77.8
13.7
15
*
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
13.6
13
*
R4190
NOMESCO Finland
Nutritional therapy
4.3
13.6
36
89
JFH10
NOMESCO Finland
Total colectomy and ileostomy
144.5
13.5
14
*
Z2446
NOMESCO Finland
Social worker
3.5
13.4
50
158
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
41.5
13.2
16
*
K90.0
ICD-10 Finland
Coeliac disease
5.9
13.0
24
43
TJF80
NOMESCO Finland
Ostomy education
23.4
13.0
18
8
TK800
NOMESCO Finland
Hemodialysis
10.2
12.9
25
26
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
72.1
12.7
14
*
JKA20
NOMESCO Finland
Cholecystectomy
9.8
12.7
25
27
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
18.0
12.6
19
11
WW500
NOMESCO Finland
Blood transfusion
5.1
12.6
27
56
K83.3
ICD-10 Finland
Fistula of bile duct
133.9
12.5
13
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
12.4
49
160
XX2RW, ,
NOMESCO Finland
11.0
12.4
23
22
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
16.5
12.3
19
12
L04AG05
ATC
vedolizumab; parenteral
48.1
11.9
14
*
WZC30
NOMESCO Finland
Teaching
2.6
11.8
81
359
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
5.8
11.8
22
40
L04AA33
ATC
[U] vedolizumab
66.9
11.7
13
*
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
+∞
11.5
11
*
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
123.3
11.5
12
*
K85
ICD-10 Finland
Acute pancreatitis
10.5
11.1
21
21
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.2
11.1
23
46
XW000
NOMESCO Finland
Bone marrow biopsy
5.2
11.1
23
46
Z3226
NOMESCO Finland
Physiotherapist
2.4
11.1
88
417
K75.4
ICD-10 Finland
Autoimmune hepatitis
61.6
10.7
12
*
K81.0
ICD-10 Finland
Acute cholecystitis
10.4
10.6
20
20
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
14.7
10.6
17
12
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.4
10.5
27
65
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
10.5
44
149
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
112.8
10.5
11
*
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
+∞
10.5
10
*
SPAT1255
SPAT
Intravenous administration of medicine
3.8
10.4
33
93
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
33.5
10.4
13
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.3
10.3
40
129
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.8
10.3
23
31
K56.0
ICD-10 Finland
Paralytic ileus
24.1
10.3
14
6
M05BA04
ATC
alendronic acid; oral
4.2
10.2
28
71
JN4BD
NOMESCO Finland
Extensive body CT
3.0
10.1
47
169
E86
ICD-10 Finland
Volume depletion
9.5
10.1
20
22
A02BC01
ATC
omeprazole; systemic
2.1
10.0
113
617
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
41.1
10.0
12
*
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
41.1
10.0
12
*
C03DA01
ATC
spironolactone; oral
2.9
10.0
49
182
UJG02
NOMESCO Finland
Proctoscopy
8.4
9.9
21
26
4AA12, ,
NOMESCO Finland
26.8
9.9
13
5
130
Kela drug reimbursment
Malignant tumour
3.2
9.8
40
133
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
13.8
9.7
16
12
ZXD05
NOMESCO Finland
Urgent procedure
2.0
9.7
134
788
JN1DM
NOMESCO Finland
Upper part of abdomen very extensive MRI examination with 3 Tesla magnet
56.3
9.7
11
*
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
9.6
105
565
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
18.1
9.5
14
8
ZX108
NOMESCO Finland
Inhalation
18.1
9.5
14
8
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
+∞
9.4
9
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
9.4
9
*
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
11.0
9.4
17
16
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
9.3
146
896
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
9.3
105
573
K56.7
ICD-10 Finland
Ileus, unspecified
10.4
9.1
17
17
4AB02, ,
NOMESCO Finland
37.6
9.1
11
*
JFF13
NOMESCO Finland
Terminal enterostomy
37.6
9.1
11
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
9.0
68
313
XX3DW
NOMESCO Finland
Time consuming IT work
2.7
9.0
52
211
ZXC86
NOMESCO Finland
Use of endoscopic device
24.6
9.0
12
5
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.7
8.9
50
200
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.7
8.7
51
208
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.7
8.7
28
80
WX600
NOMESCO Finland
Single shot through catheter
9.3
8.6
17
19
M81.8
ICD-10 Finland
Other osteoporosis
20.5
8.5
12
6
A41.9
ICD-10 Finland
Sepsis, unspecified
4.6
8.5
20
45
1280
FHL
Endoscopic retrograde cholangiography and pancreaticography
91.8
8.4
9
*
JL5BM
NOMESCO Finland
Bile and pancreas ducts MRI examination with 3 Tesla magnet
91.8
8.4
9
*
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
+∞
8.4
8
*
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
8.4
8
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.3
8.3
19
27
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
34.1
8.1
10
*
Z51.5
ICD-10 Finland
Palliative care
3.4
8.1
30
94
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
22.5
8.1
11
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
8.0
70
344
WX872
NOMESCO Finland
Intensive care
3.6
7.8
26
76
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
3.6
7.8
26
76
M81.9
ICD-10 Finland
Osteoporosis, unspecified
6.1
7.8
20
34
N02AA05
ATC
oxycodone; systemic
2.3
7.8
64
306
K81.9
ICD-10 Finland
Cholecystitis, unspecified
18.8
7.6
11
6
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
18.8
7.6
11
6
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
18.8
7.6
11
6
H26.3
ICD-10 Finland
Drug-induced cataract
18.8
7.6
11
6
R18
ICD-10 Finland
Ascites
9.1
7.6
15
17
D97
ICPC
Liver disease NOS
25.5
7.6
10
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
7.5
50
217
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
7.9
7.5
16
21
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
81.5
7.4
8
*
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
81.5
7.4
8
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
81.5
7.4
8
*
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
81.5
7.4
8
*
4AA33, ,
NOMESCO Finland
81.5
7.4
8
*
B01AB10
ATC
tinzaparin; parenteral
2.5
7.4
50
218
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.2
7.4
20
50
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
13.7
7.4
12
9
WX892
NOMESCO Finland
Monitored bed care
2.7
7.4
39
151
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
7.3
7
*
5761A
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SUPPURATIVA]
+∞
7.3
7
*
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
7.3
7
*
K83.4
ICD-10 Finland
Spasm of sphincter of Oddi
+∞
7.3
7
*
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
+∞
7.3
7
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.8
7.3
22
60
B01AB04
ATC
dalteparin; parenteral
3.5
7.2
25
75
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
6.8
7.2
17
26
JJA20
NOMESCO Finland
Open biopsy of liver
30.6
7.2
9
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.6
7.1
23
66
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.3
7.1
18
43
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.2
7.1
16
23
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
40.7
6.8
8
*
L04AF03
ATC
upadacitinib; oral
17.0
6.8
10
6
C03CA01
ATC
furosemide; systemic
2.0
6.8
76
410
B03BA03
ATC
hydroxocobalamin; parenteral
3.8
6.7
20
54
WX004
NOMESCO Finland
Patient-controlled sedation
22.9
6.7
9
*
RS220, ,
NOMESCO Finland
8.9
6.6
13
15
L04AB02
ATC
infliximab; parenteral
8.9
6.6
13
15
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
6.4
6.5
16
26
6419
FHL
Other measure in this category
70.9
6.4
7
*
8160/3-C24.9
ICD-O-3
Cholangiocarcinoma of billiary tract, NOS
70.9
6.4
7
*
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
14.6
6.4
10
7
K80.8
ICD-10 Finland
Other cholelithiasis
6.1
6.4
16
27
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
11.3
6.3
11
10
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.2
6.3
25
82
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.8
6.3
19
52
JJ9AT
NOMESCO Finland
Sampling of liver transplant under radiological guidance
+∞
6.3
6
*
K83.2
ICD-10 Finland
Perforation of bile duct
+∞
6.3
6
*
L04AA10
ATC
[U] sirolimus
+∞
6.3
6
*
8140/3-C23.9
ICD-O-3
Adenocarcinoma, NOS, of gallbladder
+∞
6.3
6
*
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
6.3
6
*
K82.0
ICD-10 Finland
Obstruction of gallbladder
+∞
6.3
6
*
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
27.1
6.2
8
*
L01BC06
ATC
capecitabine; oral
3.6
6.2
20
57
Z3231
NOMESCO Finland
Registered nurse
1.8
6.2
113
715
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.9
6.2
18
48
UJD02
NOMESCO Finland
Gastroscopy
3.1
6.1
25
84
C07AG02
ATC
carvedilol; oral
3.2
6.0
24
79
A04AA02
ATC
granisetron; systemic, transdermal
2.9
6.0
28
101

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
162
18
146.76
321.75
1.9
1.5
11.19
10.89
umol/l
0.13
162
18
330
379
38.28
309.74
4.1
1.3
—
—
—
0
0
243
80
71.64
307.65
3.2
1.3
0.87
0.63
g/l
1.53
227
67
311
105
114.39
307.65
8.7
3.2
37.38
2058.86
u/ml
0.86
294
90
280
125
66.46
307.65
3.0
1.1
67.06
69.29
titre
0.07
34
14
342
257
70.19
307.65
9.6
4.7
2.52
24.11
ug/l
0.72
279
213
276
121
65.81
307.65
2.9
1.1
—
—
—
0
0
170
38
74.96
301.78
1.9
1.1
197.00
—
titre
—
10
0
278
248
31.78
299.41
3.5
1.5
1.23
1.24
g/l
0.01
272
232
226
140
34.15
289.99
2.8
1.3
—
—
—
0
0
296
312
30.42
289.26
4.8
2.4
12.77
10.35
g/l
15.44
284
291
123
24
72.34
221.56
2.4
1.1
—
—
—
0
0
263
416
15.47
184.72
12.8
2.3
8.59
7.77
umol/l
0.25
250
371
295
558
15.74
179.76
3.1
1.4
462.76
433.50
titre
0.11
116
117
339
868
16.70
156.27
20.2
3.9
95.79
93.04
%
1.31
333
856
387
1352
27.72
128.63
23.7
9.1
1.07
1.15
inr
4.74
363
1113
234
487
9.70
123.50
3.0
2.1
—
—
—
0
0
377
1338
20.39
120.71
18.3
3.1
35.64
32.34
u/l
1.26
370
1286
216
423
9.54
119.89
3.2
2.5
22.63
24.94
%
1.26
209
401
215
469
8.42
106.23
3.4
2.4
2.43
2.40
g/l
0.35
206
439
288
864
8.58
103.26
3.7
1.4
2.50
2.30
g/l
1.49
272
565
219
505
8.05
101.93
3.4
2.5
13.25
14.50
umol/l
1.36
210
475
366
1499
12.99
92.72
6.0
2.5
73.19
73.45
nmol/l
0.06
366
1388
100
102
12.59
90.99
1.5
1.3
347.24
196.07
u/ml
2.24
55
56
67
33
24.01
89.94
1.2
1.1
—
—
—
0
0
52
12
49.38
88.29
4.8
1.9
0.59
0.62
mmol/l
1.27
52
12
63
29
25.42
86.81
1.2
1.1
—
—
—
0
0
264
906
6.24
75.87
7.3
3.9
7.39
7.40
ph
1.49
207
632
242
776
6.07
75.02
5.2
2.1
3.10
2.80
mg/l
0.86
221
683
376
1809
12.22
73.35
21.6
6.8
0.55
0.57
e9/l
0.79
366
1575
376
1812
12.18
73.12
21.6
6.8
0.04
0.04
e9/l
0.46
366
1577
282
1068
6.09
70.95
4.7
2.3
—
—
—
0
0
380
1880
12.80
70.94
22.2
7.1
0.19
0.19
e9/l
0.12
369
1660
282
1074
6.05
70.29
7.1
2.5
74.65
60.95
u/l
0.91
275
1016
377
1864
11.91
69.94
21.6
6.8
1.79
1.93
e9/l
1.90
366
1664
74
71
12.46
69.43
1.2
1.1
—
—
—
0
0
95
129
9.25
69.13
5.3
4.3
1.50
1.28
mg/l
1.67
95
119
82
96
10.39
66.87
1.5
1.4
—
—
—
0
0
80
92
10.53
66.07
1.4
1.4
142.69
142.65
au/ml
0.00
13
22
199
594
5.51
65.38
1.7
1.6
—
—
—
0
0
311
1346
6.19
64.86
12.2
7.4
1.21
1.21
mmol/l
0.02
305
1264
384
2039
12.48
62.73
25.9
10.4
3.59
4.04
e9/l
5.59
376
1779
326
1500
6.42
62.24
13.1
8.0
1.21
1.21
mmol/l
0.36
295
1325
105
189
7.09
59.08
1.4
1.4
—
—
—
0
0
295
1320
5.25
56.14
3.7
1.9
—
—
—
0
0
117
247
6.20
55.86
1.9
1.4
—
—
—
0
0
221
817
4.64
53.38
8.8
4.3
—
—
—
0
0
325
1610
5.66
53.24
32.1
10.4
0.00
0.00
e9/l
0.47
301
1319
217
800
4.58
52.40
1.9
1.7
—
—
—
0
0
61
69
10.19
50.58
1.2
1.1
—
—
—
0
0
144
419
4.73
46.61
14.4
8.8
105.33
104.38
mmol/l
1.80
144
419
207
793
4.21
46.18
4.5
2.3
—
—
—
0
0
49
50
10.97
43.57
1.4
1.3
0.48
0.29
g/l
2.04
30
39
49
50
10.97
43.57
1.4
1.3
8.93
6.28
g/l
2.84
31
39
49
50
10.97
43.57
1.4
1.4
—
—
—
0
0
49
50
10.97
43.57
1.4
1.3
3.37
2.63
g/l
1.67
30
38
315
1724
4.41
39.99
5.6
3.0
91.42
106.00
ug/l
1.37
308
1636
231
1036
3.77
39.36
14.6
6.5
—
—
—
0
0
44
45
10.82
38.97
1.3
1.3
—
—
—
0
0
127
382
4.35
38.60
1.5
1.6
—
—
—
0
0
294
1575
3.96
37.51
5.3
2.7
—
—
estimate
—
0
0
67
127
6.10
34.97
1.3
1.3
—
—
—
0
0
133
450
3.87
33.83
1.5
1.3
—
—
—
0
0
40
10
44.12
32.78
1.3
4.0
—
—
—
0
0
133
468
3.71
31.69
3.7
2.6
30.09
29.33
s
0.72
133
461
48
71
7.51
31.68
2.7
2.3
27.68
4.75
umol/l
3.77
43
53
97
274
4.31
31.54
17.3
12.2
—
—
—
0
0
98
279
4.29
31.54
7.1
5.5
0.38
0.59
%
0.56
39
88
98
280
4.27
31.38
7.8
6.3
0.00
0.05
%
0.99
36
73
100
293
4.18
30.91
7.8
5.6
0.44
0.86
%
1.61
41
96
94
274
4.14
29.15
8.1
5.8
0.03
0.14
%
1.28
35
76
42
62
7.42
27.69
1.1
1.1
—
—
—
0
0
134
515
3.36
27.33
3.0
2.8
2.21
2.15
e6/l
0.03
80
251
187
909
2.92
24.91
4.4
2.9
0.32
0.29
e6/l
0.14
150
665
36
18
21.78
24.79
3.2
4.8
8.10
9.46
mg/l
0.34
28
18
75
208
4.18
24.66
1.7
1.2
—
—
—
0
0
37
56
7.15
23.79
5.4
3.2
4.09
4.04
e9/l
0.04
37
56
77
224
3.99
23.67
2.9
2.8
77.06
75.85
e9/l
0.06
48
156
73
205
4.11
23.55
4.7
3.7
1.21
1.23
mmol/l
2.09
68
184
92
304
3.60
23.48
6.9
4.3
7.36
7.38
ph
2.63
49
174
53
116
5.09
23.37
1.9
2.2
1.14
1.49
g/l
2.14
48
106
28
7
42.78
22.96
1.0
1.0
—
—
—
0
0
28
7
42.78
22.96
1.0
1.1
—
—
—
0
0
62
159
4.41
22.52
15.3
17.8
15.69
16.14
%
0.47
62
150
200
1050
2.74
22.42
4.6
3.1
206.68
44.15
e6/l
0.40
165
801
88
293
3.54
22.12
7.2
4.3
0.33
1.62
mmol/l
2.62
79
254
131
556
2.98
21.93
3.3
2.7
0.90
1.11
e6/l
0.29
81
290
222
1238
2.70
21.92
5.3
3.7
23.50
77.58
e6/l
1.00
170
848
42
79
5.80
21.84
5.1
2.8
53.64
57.58
%
0.86
42
79
138
614
2.87
21.07
3.4
2.7
534.33
548.52
mosm/kgh2o
0.31
129
536
76
243
3.60
20.22
1.6
1.6
0.15
0.29
mg/l
1.77
17
115
69
211
3.72
19.59
2.8
1.1
0.85
0.90
g/l
0.97
69
211
148
709
2.69
19.33
3.9
2.5
5.83
5.15
e6/l
0.29
141
642
188
1020
2.54
18.89
2.0
2.1
—
—
—
0
0
228
1357
2.51
18.70
2.6
1.9
92.69
96.48
pmol/l
0.73
141
721
24
9
28.18
18.01
1.1
1.0
—
—
—
0
0
25
12
22.07
17.51
3.6
2.9
5.28
5.74
ug/l
0.09
25
12
103
432
2.84
17.17
1.4
1.2
—
—
—
0
0
30
52
6.14
16.89
2.9
3.0
—
—
—
0
0
409
3583
9.41
16.66
58.0
13.0
16.96
21.86
mg/l
4.91
400
2851
174
955
2.41
16.55
1.6
1.3
1.39
1.61
u/ml
0.17
45
278
164
886
2.40
16.06
12.2
5.0
—
—
—
0
0
83
321
2.98
15.97
15.9
12.8
7.40
7.42
ph
0.56
31
184
82
317
2.98
15.78
16.1
12.9
-0.62
0.99
mmol/l
3.06
71
265
76
290
2.98
14.92
17.2
13.6
97.09
95.70
%
1.04
76
279
191
1133
2.27
14.74
1.7
1.5
—
—
—
0
0
384
3124
3.98
14.39
59.6
16.4
13.76
13.35
%
7.32
384
3091
72
275
2.96
14.07
17.0
13.4
117.54
124.48
g/l
1.68
72
267
20
10
20.93
13.91
1.5
1.8
122.48
—
au/ml
—
5
0
114
567
2.39
13.04
2.3
1.6
474.65
30784751.98
pmol/l
0.69
100
510
96
453
2.45
12.27
4.3
3.2
3.65
4.88
e9/l
1.62
87
409
33
83
4.23
12.16
4.6
2.9
2.80
3.05
index
0.09
20
44
68
272
2.79
12.14
4.0
3.1
—
—
—
0
0
25
51
5.15
11.83
3.3
2.5
1.99
2.93
mmol/l
1.01
14
35
15
6
25.84
11.21
3.3
1.2
—
—
—
0
0
143
863
2.00
9.63
4.8
2.7
352.59
340.85
umol/l
0.65
135
790
84
415
2.28
9.50
2.1
1.6
1219.34
1144.63
nmol/l
0.25
64
329
20
26
8.02
9.24
1.2
1.0
1362.60
1663.85
miu/ml
0.62
20
26
251
1860
1.88
8.82
4.2
3.4
0.00
0.00
estimate
-0.00
69
385
254
1894
1.88
8.70
4.2
3.4
0.00
0.01
estimate
0.50
70
360
252
1875
1.87
8.69
4.2
3.4
23.50
4.23
estimate
0.37
70
384
164
1072
1.87
8.50
2.4
2.7
—
0.14
—
0
14
86
455
2.12
8.14
2.2
1.5
—
—
—
0
0
28
84
3.50
8.08
1.4
1.3
253.20
302.44
ug/g
0.48
19
48
210
1503
1.80
7.96
3.3
3.1
5.91
6.17
ph
3.20
116
882
12
8
15.39
7.76
3.3
1.3
—
—
—
0
0
157
1068
1.75
6.80
5.1
3.1
2.33
2.35
mmol/l
2.26
151
978
370
3237
2.29
6.78
54.6
16.5
332.30
334.20
g/l
3.86
370
3227
40
164
2.59
6.75
2.3
2.7
—
—
—
0
0
14
20
7.20
6.27
4.4
2.5
1.86
0.80
index
0.78
14
20
93
555
1.87
6.14
4.8
2.7
2.45
2.44
mmol/l
0.67
87
501
16
29
5.69
6.05
1.3
1.1
—
—
—
0
0
123
807
1.74
5.91
2.3
2.0
1.60
1.04
mg/l
0.99
102
609
8
5
16.26
5.43
1.3
1.4
—
—
—
0
0
28
110
2.66
5.16
1.3
1.2
—
—
—
0
0
22
76
3.00
5.11
2.8
4.3
42.39
117.68
mg/l
0.50
16
67
22
76
3.00
5.11
2.8
4.3
36.96
27.59
mg/l
1.15
16
66
20
68
3.04
4.78
2.9
3.9
1.17
2.65
ratio
—
6
37
191
1478
1.54
4.46
2.4
1.9
1.35
1.43
mmol/l
0.67
182
1294
402
3764
3.02
4.38
36.1
11.2
—
—
—
0
0
43
222
2.04
4.30
3.6
3.5
7.40
7.42
ph
0.94
38
193
94
621
1.66
4.27
3.8
3.5
19.09
326.48
ng/l
3.32
65
420
37
183
2.12
4.14
1.6
2.3
1.75
5.17
iu/ml
—
6
41
13
31
4.29
4.04
2.4
1.4
32.00
33.32
pg
0.50
13
31
34
166
2.14
3.93
6.6
3.3
0.67
0.60
%
0.50
34
166
13
32
4.16
3.93
2.5
1.4
1.06
1.08
%
0.04
13
19
29
133
2.27
3.90
1.2
1.1
—
—
—
0
0
158
1200
1.51
3.90
4.2
3.2
22.36
28.64
ng/l
0.49
100
726
135
993
1.53
3.86
4.9
3.4
0.01
0.00
estimate
0.36
71
362
113
800
1.57
3.83
2.8
2.7
—
—
—
0
0
7
8
8.87
3.78
5.0
2.9
47.86
52.31
%
—
7
8
14
39
3.68
3.73
2.0
2.4
8.73
11.96
%
1.45
14
39
28
135
2.15
3.36
1.1
1.2
—
—
—
0
0
10
23
4.43
3.33
1.4
1.1
—
—
—
0
0
13
43
3.09
3.28
1.6
1.6
—
—
—
0
0
9
19
4.82
3.25
1.9
3.8
4530.78
743.89
u/ml
—
9
19
15
55
2.79
3.19
2.7
2.4
—
—
—
0
0
5
5
10.10
2.98
1.2
1.4
—
—
—
0
0
5
5
10.10
2.98
2.4
1.0
—
—
—
0
0
380
3553
1.80
2.94
7.4
4.6
4.57
4.70
mmol/l
2.03
373
3382
11
32
3.50
2.92
1.4
1.1
—
—
—
0
0
178
1447
1.40
2.86
4.2
3.1
0.02
0.01
estimate
0.15
63
319
5
6
8.41
2.75
1.6
7.8
21.24
25.60
mmol/l
—
5
6
5
6
8.41
2.75
1.2
1.3
—
—
—
0
0
22
106
2.14
2.68
5.2
10.1
0.88
0.88
%
0.03
22
97
35
200
1.82
2.66
1.1
1.1
—
—
—
0
0
0
69
0.00
2.62
0.0
7.3
—
378.61
—
0
61
12
44
2.78
2.57
1.9
1.7
—
—
—
0
0
12
44
2.78
2.57
1.9
1.7
—
—
—
0
0
12
44
2.78
2.57
1.9
1.7
—
—
—
0
0
12
44
2.78
2.57
1.9
1.7
—
—
—
0
0
7
16
4.43
2.48
1.1
1.3
—
—
—
0
0
49
318
1.61
2.38
1.2
1.2
—
—
—
0
0
11
39
2.87
2.36
1.4
1.2
—
—
—
0
0
26
141
1.90
2.33
1.8
1.8
—
—
—
0
0
14
59
2.42
2.31
2.6
3.4
8.51
8.02
pmol/l
0.07
14
59
13
53
2.50
2.30
1.9
2.0
—
—
—
0
0
7
18
3.94
2.26
1.7
1.3
—
—
—
0
0
23
122
1.94
2.21
5.0
9.1
1.41
1.58
%
0.39
23
113
15
67
2.29
2.20
1.9
1.9
—
—
—
0
0
10
36
2.82
2.15
1.4
1.1
—
—
—
0
0
13
55
2.41
2.14
1.2
1.3
—
—
—
0
0
140
1137
1.35
2.14
3.6
3.3
8.57
8.67
mmol/l
0.08
128
1004
136
1104
1.34
2.07
3.9
2.7
0.00
0.00
estimate
0.50
61
306
11
44
2.54
2.02
1.0
1.1
—
—
—
0
0
7
21
3.37
1.97
1.7
1.0
—
—
—
0
0
140
1672
0.75
1.96
3.6
2.7
—
—
—
0
0
9
33
2.76
1.94
1.7
1.2
—
—
—
0
0
297
2708
1.34
1.94
4.5
4.1
14.43
14.60
pmol/l
0.57
286
2517
28
168
1.71
1.86
1.3
1.4
213.33
271.86
miu/ml
0.33
13
82
9
35
2.61
1.81
2.0
3.1
—
—
—
0
0
8
30
2.70
1.73
1.6
1.3
—
—
—
0
0
20
112
1.83
1.67
1.2
1.1
—
—
—
0
0
20
112
1.83
1.67
1.2
1.1
—
—
—
0
0
27
422
0.61
1.67
1.4
1.7
—
—
—
0
0
47
651
0.69
1.65
2.4
2.6
0.82
0.69
ug/l
0.26
25
338
12
56
2.18
1.62
5.2
15.7
12.25
11.44
mmol/l
0.41
12
48
12
56
2.18
1.62
5.2
15.7
106.58
104.85
mmol/l
0.70
12
48
114
932
1.31
1.62
3.7
3.5
34.04
62.79
mg/l
1.62
72
621
115
945
1.30
1.57
4.6
4.2
6.80
10.18
mg/mmol
0.65
74
616
56
418
1.39
1.44
1.8
1.6
—
—
—
0
0
5
16
3.15
1.44
1.6
1.4
89.40
70.41
ug/l
—
5
16
5
17
2.96
1.36
1.8
1.5
25.80
27.65
s
—
5
17
6
24
2.52
1.31
1.0
1.1
—
—
—
0
0
6
24
2.52
1.31
1.3
1.5
—
—
—
0
0
5
18
2.80
1.29
1.6
1.8
—
—
—
0
0
8
36
2.25
1.25
2.1
2.1
42.23
40.34
%
—
8
36
8
37
2.18
1.22
1.0
1.4
27.00
27.75
ng/l
—
8
37
5
21
2.40
1.09
2.0
3.2
—
—
—
0
0
353
3382
1.29
1.07
5.4
3.9
1.20
1.31
mmol/l
2.83
343
3190
7
33
2.14
1.06
2.3
2.8
—
—
—
0
0
43
557
0.75
1.03
1.3
1.4
—
—
—
0
0
9
48
1.89
1.01
1.1
1.2
—
—
—
0
0
7
132
0.52
1.00
1.4
2.1
—
—
—
0
0
0
29
0.00
0.98
0.0
1.1
—
0.31
—
0
14
20
134
1.52
0.93
3.1
3.7
23.60
24.75
mmol/l
1.38
20
127
18
265
0.66
0.91
1.1
1.1
—
—
—
0
0
32
423
0.74
0.89
1.5
1.7
3.15
3.52
mmol/l
1.19
21
304
23
161
1.45
0.88
1.7
1.4
5.31
7.62
u/l
1.10
18
129
6
32
1.89
0.82
1.3
1.2
7.17
9.78
mm/h
—
6
32
23
165
1.42
0.79
3.2
3.6
—
—
—
0
0
48
589
0.79
0.79
1.7
1.9
—
—
—
0
0
23
166
1.41
0.77
7.3
7.8
—
—
—
0
0
5
24
2.10
0.74
1.2
1.5
—
—
—
0
0
5
24
2.10
0.74
1.2
2.0
6.32
5.62
mmol/l
—
5
17
5
26
1.93
0.71
1.0
1.2
95.40
108.15
pmol/l
—
5
26
5
26
1.93
0.71
1.8
1.3
—
—
—
0
0
53
441
1.23
0.68
1.5
1.4
—
—
—
0
0
364
3541
1.22
0.66
6.4
4.5
1.51
1.41
mmol/l
5.02
356
3356
36
287
1.28
0.66
1.2
1.3
97.99
135.46
u/ml
—
9
122
10
62
1.63
0.65
1.1
1.3
30.55
10.47
u/l
—
10
56
336
3247
1.18
0.65
5.3
4.9
1.90
1.83
mu/l
0.45
323
3059
30
234
1.30
0.65
2.0
2.4
—
—
—
0
0
38
307
1.26
0.63
2.4
2.0
0.00
0.04
estimate
—
10
84
17
122
1.41
0.61
1.2
1.2
—
2.76
—
0
13
7
112
0.62
0.59
1.3
1.3
—
—
—
0
0
8
55
1.46
0.56
1.5
1.4
—
—
—
0
0
6
39
1.55
0.53
1.2
1.2
—
—
nmol/l
—
0
0
366
3584
1.18
0.47
6.5
5.1
2.64
2.82
mmol/l
3.94
356
3401
22
174
1.28
0.46
13.6
10.4
23.42
24.65
mmol/l
0.93
22
164
7
50
1.41
0.45
1.3
1.3
—
—
—
0
0
6
91
0.65
0.43
1.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
2.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
22
178
1.25
0.39
2.5
2.1
0.00
0.06
estimate
—
9
68
0
19
0.00
0.39
0.0
1.3
—
80.02
—
0
14
0
19
0.00
0.39
0.0
1.7
—
1.15
—
0
14
321
3284
0.90
0.36
6.9
5.3
36.96
38.10
mmol/mol
1.76
313
3133
25
208
1.21
0.36
1.2
1.1
1.56
1.51
g/l
0.53
25
208
5
80
0.62
0.35
1.0
1.1
—
9.40
—
0
44
23
276
0.82
0.35
1.6
1.8
—
—
—
0
0
25
209
1.21
0.35
1.5
1.4
32.20
19.70
iu/l
0.64
20
173
29
339
0.84
0.34
1.8
1.9
—
—
—
0
0
17
136
1.26
0.34
10.7
4.8
37.07
36.94
°c
1.60
17
136
6
45
1.34
0.34
1.3
1.5
179.78
176.52
pmol/l
—
6
45
29
338
0.85
0.33
1.8
2.0
—
—
—
0
0
25
214
1.18
0.28
2.1
2.0
45.00
35.53
nmol/l
0.95
25
208
30
343
0.86
0.28
1.8
2.0
—
—
—
0
0
30
342
0.87
0.27
1.8
1.9
—
—
—
0
0
13
104
1.26
0.26
1.2
1.1
—
—
—
0
0
10
77
1.31
0.26
1.0
1.2
—
—
—
0
0
340
3349
1.08
0.23
4.4
4.3
5.72
5.80
mmol/l
0.50
330
3135
5
42
1.19
0.21
2.6
1.7
10.00
10.69
mmol/l
—
5
42
0
11
0.00
0.21
0.0
1.4
—
75.85
—
0
11
0
10
0.00
0.21
0.0
1.0
—
0.38
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
43.18
—
0
12
0
12
0.00
0.21
0.0
1.2
—
63.83
—
0
12
0
13
0.00
0.21
0.0
3.1
—
37.30
—
0
8
0
13
0.00
0.21
0.0
2.1
—
13.15
—
0
13
0
13
0.00
0.21
0.0
2.4
—
5.39
—
0
13
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
9
111
0.81
0.20
1.4
1.5
—
—
—
0
0
9
115
0.78
0.20
1.6
1.6
—
—
—
0
0
5
68
0.73
0.17
1.4
1.1
—
—
—
0
0
20
177
1.14
0.16
2.3
1.9
209.05
233.72
pmol/l
0.87
20
168
6
79
0.76
0.15
1.0
1.6
—
—
—
0
0
29
317
0.91
0.15
1.8
2.0
—
—
—
0
0
15
131
1.15
0.14
3.3
1.9
—
—
—
0
0
22
200
1.11
0.12
2.3
2.6
2364.29
4971.87
u/l
—
8
83
15
133
1.13
0.12
3.2
3.1
1.01
1.02
ratio
2.01
15
124
13
147
0.88
0.11
1.7
2.4
—
—
—
0
0
68
654
1.05
0.10
1.3
1.3
5.55
9.91
u/ml
0.44
26
260
5
44
1.14
0.10
12.0
2.3
—
—
—
0
0
67
645
1.05
0.10
1.6
1.6
—
—
—
0
0
12
108
1.11
0.07
10.2
7.3
—
—
—
0
0
7
82
0.85
0.07
2.6
2.5
—
—
—
0
0
7
84
0.83
0.07
1.0
1.4
—
—
—
0
0
88
859
1.03
0.07
4.6
3.3
1.02
1.02
kg/l
0.49
65
566
73
712
1.03
0.06
1.3
1.3
19.12
26.12
iu/ml
0.58
27
209
24
227
1.06
0.06
1.4
1.7
—
—
—
0
0
25
263
0.95
0.05
2.6
2.5
6.62
15.00
au/ml
—
5
29
24
234
1.03
0.00
1.0
1.2
—
—
—
0
0
28
274
1.02
0.00
2.6
1.8
6.14
6.16
ph
0.05
18
166
0
9
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
8.20
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
31.54
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
64
0.94
-0.00
7.0
3.0
1.13
1.45
mmol/l
—
6
64
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.03
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
2.11
—
0
6
5
55
0.91
-0.00
1.4
1.4
384.80
293.70
mu/l
—
5
46
6
67
0.89
-0.00
5.0
3.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_PSC_COLITIS_STRICT and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
K11_PSC_COLITIS_STRICT 2.174 [1.71, 2.76] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 113 out of 793 males with K11_PSC_COLITIS_STRICT died.

Mortality risk

Mortality risk for people of age

years, who have K11_PSC_COLITIS_STRICT.

N-year risk Females Males
1 No data 0.422%
5 No data 2.357%
10 No data 5.82%
15 No data 11.196%
20 No data 19.291%

Relationships between endpoints

Index endpoint: K11_PSC_COLITIS_STRICT – Colitis, primary sclerosing, strict definition

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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