animal viral hepatitis: A hepatitis that involves viral infection of an animal causing inflammation of the liver.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
103 |
4. Check minimum number of eventsNone |
103 |
5. Include endpointsNone |
103 |
6. Filter based on genotype QC (FinnGen only) |
95 |
Control definitions (FinnGen only)
- Control exclude
- IBD_CMV
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Cytomegaloviral hepatitis
based on the number of shared cases.
Similar with more cases:
- Cytomegalovirus infection, IBD co-morbidity
- Cytomegaloviral disease
- Cytomegaloviral disease, including avohilmo
- Infections, IBD-co-morbidities
- Other viral diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 572 | 309 | 258 |
| Only index persons | 496 | 268 | 228 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 39.29 | 44.09 | 33.25 |
| Only index persons | 38.68 | 43.17 | 33.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 95 | 60 | 35 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 43.81 | 46.57 | 39.09 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 98
- Matched controls
- 980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K77.0*B25.1
ICD-10 Finland
Cytomegaloviral hepatitis
+∞
67.8
57
*
B25.1
ICD-10 Finland
Cytomegaloviral hepatitis
+∞
23.9
22
*
0785B
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Cytomegaloviral disease[HEPATITIS CYTOMEGALICA]
+∞
20.5
19
*
R50.9
ICD-10 Finland
Fever, unspecified
6.7
19.1
43
102
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.6
13.6
26
51
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
26.9
12.0
16
7
L04AA06
ATC
mycophenolic acid; systemic
24.9
11.1
15
7
A05AA02
ATC
ursodeoxycholic acid; oral
32.2
11.1
14
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.3
11.0
27
66
127
Kela drug reimbursment
Transplant complication
26.9
10.6
14
6
Z94.4
ICD-10 Finland
Liver transplant status
55.1
8.9
10
*
L04AD02
ATC
tacrolimus; systemic
55.1
8.9
10
*
K76.9
ICD-10 Finland
Liver disease, unspecified
98.1
8.6
9
*
L04AX01
ATC
azathioprine; systemic
11.6
8.4
15
15
TK800
NOMESCO Finland
Hemodialysis
27.5
7.7
10
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.0
7.7
17
25
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
+∞
7.4
7
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
+∞
7.4
7
*
K83.0
ICD-10 Finland
Cholangitis
32.7
7.3
9
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
15.3
7.1
11
8
L04AD01
ATC
ciclosporin; systemic
12.2
6.5
11
10
H02AB04
ATC
methylprednisolone; systemic
3.5
6.4
26
91
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
22
15.63
15.75
1.3
1.1
82.30
178.07
au/ml
—
10
6
23
19
15.42
14.00
1.1
1.1
452.20
175.18
u/ml
—
10
11
33
129
3.35
6.86
6.0
3.0
2.76
3.09
e6/l
0.07
18
67
17
33
6.00
6.38
6.4
3.0
1.99
1.41
mg/l
1.32
17
28
15
26
6.61
6.13
1.6
1.3
—
—
—
0
0
47
238
2.87
6.12
5.5
2.9
0.13
0.37
e6/l
1.33
36
169
33
142
3.00
5.73
5.8
2.9
0.44
0.91
e6/l
1.26
18
78
9
7
13.98
5.70
1.1
1.0
—
—
—
0
0
27
104
3.20
5.65
2.1
2.0
—
—
—
0
0
65
417
2.66
4.98
15.6
7.1
1.21
1.22
mmol/l
0.56
59
364
32
146
2.77
4.91
2.2
2.1
—
—
—
0
0
16
48
3.79
4.85
9.2
2.2
24.29
24.72
mmol/l
0.22
16
48
26
108
2.92
4.72
2.0
1.9
—
—
—
0
0
75
524
2.84
4.72
21.7
11.7
4.04
3.89
e9/l
0.22
70
464
13
29
5.00
4.44
2.8
1.9
97.15
93.93
%
0.14
13
29
14
44
3.55
3.95
2.3
1.8
—
—
—
0
0
7
8
9.31
3.84
1.6
1.4
—
—
—
0
0
13
35
4.12
3.76
1.7
1.2
—
—
—
0
0
36
198
2.29
3.59
2.7
2.4
—
—
—
0
0
9
19
5.10
3.33
3.7
2.7
4.77
6.07
u/ml
—
9
19
5
5
10.43
3.01
3.2
2.8
0.60
0.80
index
—
5
5
13
47
3.04
2.95
3.3
1.6
3.48
5.35
iu/ml
—
5
11
16
67
2.66
2.80
3.2
2.2
47.83
76.07
ml/min/173m2
—
6
28
10
31
3.47
2.60
1.4
1.4
—
—
—
0
0
12
46
2.83
2.46
7.4
9.6
94.41
95.18
%
0.49
12
46
6
13
4.84
2.31
1.0
1.3
—
—
—
0
0
6
13
4.84
2.31
1.5
1.0
—
—
—
0
0
12
49
2.65
2.20
4.8
2.3
—
—
—
0
0
15
69
2.39
2.18
16.0
3.1
109.07
69.57
ng/l
0.75
15
60
62
475
1.83
2.14
7.8
3.8
0.00
0.00
estimate
-0.00
15
96
57
426
1.81
2.14
4.9
2.9
104.56
101.10
ug/l
0.07
52
403
61
468
1.80
2.07
7.4
3.7
0.00
0.00
estimate
-0.00
17
101
5
11
4.72
1.96
1.6
1.1
128.40
112.45
%
—
5
11
18
94
2.12
1.96
3.4
2.5
38.61
28.68
u/l
1.07
18
75
17
87
2.15
1.94
2.9
3.3
—
—
—
0
0
5
12
4.33
1.84
1.0
1.1
—
—
—
0
0
8
29
2.91
1.83
2.5
1.2
—
—
—
0
0
54
411
1.70
1.79
3.1
2.7
—
—
estimate
—
0
0
31
203
1.77
1.75
2.5
2.2
2.72
2.55
mg/l
0.19
25
182
13
63
2.23
1.68
6.2
4.6
1.23
1.22
mmol/l
0.16
13
56
7
25
2.93
1.68
1.9
2.6
0.00
0.00
g/l
—
7
25
10
42
2.53
1.67
2.3
1.1
0.89
0.88
g/l
—
10
42
8
32
2.63
1.63
1.9
2.3
6.79
7.77
g/l
—
8
32
8
32
2.63
1.63
1.9
2.3
4.06
4.73
g/l
—
8
32
8
32
2.63
1.63
1.9
2.3
3.71
3.80
g/l
—
8
32
12
57
2.26
1.63
6.7
2.5
—
—
—
0
0
5
15
3.45
1.54
1.6
1.5
—
—
—
0
0
59
473
1.62
1.50
8.1
3.8
0.00
0.00
estimate
-0.00
17
102
71
597
1.69
1.48
3.9
3.3
—
—
—
0
0
18
106
1.86
1.41
7.1
6.9
104.72
103.80
mmol/l
0.27
18
106
9
44
2.15
1.31
3.0
1.4
—
—
—
0
0
28
193
1.63
1.29
2.3
1.8
0.66
1.17
mg/l
0.76
22
161
8
36
2.33
1.27
3.3
2.3
0.78
1.02
%
—
8
36
8
37
2.26
1.25
4.1
1.4
0.23
0.24
g/l
—
8
37
8
37
2.26
1.25
4.1
1.4
1.14
1.20
g/l
—
8
37
16
97
1.78
1.15
2.0
1.9
358.56
401.22
nmol/l
0.34
16
91
7
30
2.43
1.15
1.9
2.4
3.44
2.98
g/l
—
7
30
7
30
2.43
1.15
1.4
1.7
—
—
—
0
0
11
59
1.97
1.12
3.3
1.5
—
—
—
0
0
7
33
2.21
1.08
1.6
2.1
—
—
—
0
0
5
22
2.34
1.04
1.4
1.6
—
—
—
0
0
22
151
1.59
1.02
1.8
1.6
—
—
—
0
0
6
28
2.22
0.93
1.5
1.8
—
—
—
0
0
28
208
1.48
0.92
1.6
1.6
—
—
—
0
0
32
247
1.44
0.86
6.9
4.0
0.00
0.00
estimate
-0.00
15
94
6
32
1.93
0.83
1.5
1.4
—
—
—
0
0
46
387
1.36
0.73
2.0
2.1
109.38
96.99
pmol/l
0.96
32
193
5
27
1.90
0.69
2.4
1.3
—
—
—
0
0
5
27
1.90
0.69
2.4
1.3
—
—
—
0
0
0
21
0.00
0.61
0.0
1.9
—
—
—
0
0
18
134
1.42
0.58
1.6
1.6
1526.15
1194.67
nmol/l
0.45
13
99
25
205
1.29
0.45
7.0
3.9
1.02
1.02
kg/l
0.62
18
137
5
34
1.50
0.41
2.0
2.3
—
—
—
0
0
16
125
1.33
0.40
3.0
2.2
—
—
—
0
0
22
182
1.27
0.37
1.4
1.3
11.91
9.41
u/ml
—
9
71
24
201
1.26
0.37
1.4
1.4
22.12
26.79
iu/ml
—
9
75
85
816
1.31
0.34
5.7
5.8
37.26
38.97
mmol/mol
1.11
79
776
10
75
1.37
0.31
1.5
1.4
—
—
—
0
0
40
360
1.19
0.31
7.8
3.6
0.00
0.01
estimate
0.49
11
84
14
115
1.25
0.25
3.1
2.1
—
—
—
0
0
31
279
1.16
0.23
7.9
3.1
0.00
0.00
estimate
-0.00
12
82
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
565.83
—
0
6
0
11
0.00
0.21
0.0
5.9
—
107.43
—
0
11
0
11
0.00
0.21
0.0
1.0
—
37.17
—
0
6
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
30
330
0.87
0.21
4.7
3.5
34.00
34.91
ng/l
0.02
24
209
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
14
164
0.83
0.20
5.5
4.1
22.81
22.50
%
—
7
75
11
127
0.85
0.13
1.6
2.1
3.64
3.44
ratio
—
5
104
27
250
1.11
0.13
7.3
4.1
12.57
6.47
mg/mmol
0.50
18
149
79
808
0.89
0.12
5.1
5.5
1.76
1.86
mu/l
0.35
74
747
25
235
1.09
0.08
1.4
1.3
0.71
0.71
u/ml
—
7
60
10
94
1.07
0.01
22.5
6.7
—
—
—
0
0
68
685
0.98
0.00
4.3
4.7
14.68
14.75
pmol/l
0.09
63
633
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.8
—
224.20
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
14.90
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
121.57
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
0.30
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
1011.14
—
0
7
0
5
0.00
-0.00
0.0
11.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CMV_HEPATITIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have CMV_HEPATITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: CMV_HEPATITIS – Cytomegaloviral hepatitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data