No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
611 |
4. Check minimum number of eventsNone |
611 |
5. Include endpointsNone |
611 |
6. Filter based on genotype QC (FinnGen only) |
562 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
Asymmetry of jaw
based on the number of shared cases.
Similar with more cases:
- Dentofacial anomalies [including malocclusion]
- Diseases of oral cavity, salivary glands and jaws
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5892 | 3581 | 2294 |
| Only index persons | 5631 | 3444 | 2187 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.06 |
| Only index persons | 0.11 | 0.13 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 19.42 | 20.42 | 17.77 |
| Only index persons | 20.03 | 21.27 | 18.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 562 | 421 | 141 |
| Unadjusted period prevalence (%) | 0.13 | 0.15 | 0.06 |
| Median age at first event (years) | 31.96 | 31.30 | 33.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 579
- Matched controls
- 5790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.13
ICD-10 Finland
Retrognaty, mandibular
63.0
307.7
218
55
K07.10
ICD-10 Finland
Asymmetry of jaw
+∞
307.7
578
*
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
210.0
307.7
213
16
SBB10
NOMESCO Finland
Dental impressions
17.1
274.9
331
419
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
26.2
254.2
196
111
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
21.6
254.2
221
161
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
16.3
240.4
261
277
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
20.4
234.4
207
154
EB1MA
NOMESCO Finland
Cephalometry with X-ray
21.1
220.3
187
128
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
17.8
209.1
197
163
K07.24
ICD-10 Finland
Open bite
41.6
208.1
130
40
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
18.2
202.2
186
147
SJC10
NOMESCO Finland
Orthodontic band in one tooth
20.0
196.0
168
116
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
17.7
193.9
180
144
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
26.8
185.1
135
65
EEC05
NOMESCO Finland
Le Fort I osteotomy
351.6
160.3
155
6
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
14.3
155.5
161
152
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
13.9
152.8
161
156
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
61.7
142.5
80
15
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
17.9
138.9
121
84
SAA04
NOMESCO Finland
Special examination of mouth
10.0
127.7
175
241
K07.60
ICD-10 Finland
Snapping jaw
9.4
118.6
169
243
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
12.2
103.4
113
113
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
246.9
102.1
102
5
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
11.1
95.4
111
121
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
10.1
94.7
119
144
K07.14
ICD-10 Finland
Retrognaty, maxillary
145.3
93.2
97
8
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
6.0
92.9
227
560
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
13.7
89.7
89
76
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
11.1
88.7
102
109
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
163.3
81.4
84
6
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
9.7
77.2
98
119
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
6.2
75.2
155
321
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
7.2
73.2
125
214
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
36.5
69.6
44
13
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
13.1
69.1
69
59
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
136.7
68.6
72
6
EBB10
NOMESCO Finland
Insertion of dental implant
21.9
68.6
52
26
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
195.4
67.6
69
*
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
7.7
66.1
103
159
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
16.8
63.9
55
36
K07.23
ICD-10 Finland
Deep bite
8.3
63.7
91
127
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
179.5
62.3
64
*
SAA03
NOMESCO Finland
Extended examination of mouth
4.4
59.8
415
2118
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
7.3
56.4
91
145
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
75.5
54.3
61
9
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
17.1
54.3
46
29
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
22.5
53.7
40
19
SXC05
NOMESCO Finland
Other oral or dental procedure
5.0
52.9
137
340
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
279.0
50.9
51
*
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
16.7
49.0
42
27
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
14.3
48.2
45
34
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
5.6
47.1
99
204
WZC00
NOMESCO Finland
Treatment plan or consultation
3.3
44.5
334
1678
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
5.8
42.6
86
170
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
10.1
40.3
47
50
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
62.3
39.9
46
8
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
10.3
39.1
45
47
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
5.2
38.8
89
197
SPC10
NOMESCO Finland
Standard dental crown
13.7
36.9
35
27
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
5.6
36.3
75
151
EDC30
NOMESCO Finland
Genioplasty
368.5
35.3
35
*
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
7.4
33.2
50
73
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
11.6
31.4
33
30
Z3229
NOMESCO Finland
Other healthcare associate professional
4.7
30.4
77
184
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.7
29.5
341
2012
SPC20
NOMESCO Finland
Implant borne crown
35.8
29.1
37
11
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
6.2
28.5
51
89
K01.0
ICD-10 Finland
Embedded teeth
6.5
28.1
48
80
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
9.9
26.4
31
33
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.5
26.2
68
165
ZXA10
NOMESCO Finland
Bilateral
3.1
26.0
130
492
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
30.0
25.7
34
12
SJA02
NOMESCO Finland
Workplan for orthodontic treatment
70.6
24.0
27
*
L01BA01
ATC
methotrexate; systemic
6.2
23.4
41
70
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
22.5
22.4
32
15
K00.00
ICD-10 Finland
Hypodontia
7.4
22.3
33
47
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
228.3
21.7
22
*
P01BA02
ATC
hydroxychloroquine; oral
3.6
21.6
78
240
EB1WA, ,
NOMESCO Finland
21.8
21.5
31
15
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
7.7
21.0
30
41
EBB15
NOMESCO Finland
Insertion of dental implant abutment
26.7
20.6
28
11
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
21.0
20.6
30
15
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
18.5
19.8
30
17
L04AX03
ATC
methotrexate; systemic
3.2
19.5
87
305
SXC03
NOMESCO Finland
Other oral or dental procedure
15.5
19.1
31
21
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.6
18.9
66
198
K07.4
ICD-10 Finland
Malocclusion, unspecified
6.2
18.9
33
56
EBA10
NOMESCO Finland
Operative extraction of tooth
2.4
18.9
163
804
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.0
18.6
90
331
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
6.5
18.2
30
48
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
54.3
18.1
21
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
17.7
174
905
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
98.1
17.7
19
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.9
17.3
90
344
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
18.1
17.1
26
15
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
7.2
16.7
25
36
EEC02
NOMESCO Finland
Rapid expansion of maxilla
92.8
16.6
18
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.1
16.6
78
281
ZXX07
NOMESCO Finland
Extent of procedure, 7 units
87.5
15.6
17
*
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
39.2
15.5
19
5
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.2
15.0
41
103
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
5.4
15.0
30
58
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.3
14.8
25
41
SJE90
NOMESCO Finland
Orthodontic finishing
17.5
14.4
22
13
R06.5
ICD-10 Finland
Mouth breathing
2.9
13.9
69
256
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
13.7
187
1090
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
13.5
57
193
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.0
13.4
62
221
A07EC01
ATC
sulfasalazine; oral, rectal
3.0
13.4
61
216
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.3
12.8
106
505
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.0
12.8
37
97
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
71.5
12.6
14
*
K07.9
ICD-10 Finland
Dentofacial anomaly, unspecified
132.8
12.5
13
*
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
14.7
12.3
20
14
J01CE02
ATC
phenoxymethylpenicillin; oral
2.1
12.2
441
3525
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
18.5
12.1
18
10
G50.1
ICD-10 Finland
Atypical facial pain
6.0
11.9
21
36
EEC45
NOMESCO Finland
Reconstruction of maxilla using bone graft
66.3
11.6
13
*
K07.0
ICD-10 Finland
Major anomalies of jaw size
66.3
11.6
13
*
TEG00
NOMESCO Finland
Punction of mandibular joint
66.3
11.6
13
*
Z01.2
ICD-10 Finland
Dental examination
1.9
11.6
337
2485
SPB20
NOMESCO Finland
Temporary bridge
23.5
11.6
16
7
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
11.3
209
1336
EB1TW
NOMESCO Finland
3D modelling of dentition
25.6
11.2
15
6
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
20.5
11.2
16
8
OIKK, ,
NOMESCO Finland
3.0
11.2
52
186
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
11.1
197
1244
ZXE00
NOMESCO Finland
One hour or less
1.8
10.9
233
1557
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
18.2
10.8
16
9
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
28.6
10.8
14
5
SAA02
NOMESCO Finland
Basic examination of mouth
2.1
10.7
472
3931
EGC30
NOMESCO Finland
Prosthetic replacement of mandibular joint
112.0
10.5
11
*
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
+∞
10.4
10
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
10.4
10
*
K07.08
ICD-10 Finland
Other specified anomaly in the size of the cores
+∞
10.4
10
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
10.4
115
614
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.6
10.0
33
95
5241A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Anomalies of relationship of jaw to cranial base
40.8
10.0
12
*
Z2221
NOMESCO Finland
Medical doctor
1.9
9.9
169
1046
K07.61
ICD-10 Finland
Cracking jaw joint
3.6
9.9
33
96
L04AB01
ATC
etanercept; parenteral
5.1
9.6
20
40
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
37.3
9.0
11
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.5
9.0
31
92
ZXD20
NOMESCO Finland
Day surgery
2.2
8.8
81
401
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
8.6
56
238
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
16.6
8.6
13
8
G47.3
ICD-10 Finland
Sleep apnoea
1.9
8.6
121
701
L88
ICPC
Rheumatoid/seropositive arthritis
3.3
8.5
32
101
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.2
8.4
33
107
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
+∞
8.4
8
*
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
17.5
8.1
12
7
Q67.0
ICD-10 Finland
Facial asymmetry
33.9
8.1
10
*
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
33.9
8.1
10
*
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
8.0
156
996
Z3226
NOMESCO Finland
Physiotherapist
2.0
8.0
102
570
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
6.7
7.9
19
29
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.8
7.9
40
150
R4110
NOMESCO Finland
Physiotherapy
1.8
7.7
148
942
ZZH22
NOMESCO Finland
Graft of patients own bone, block
18.6
7.6
11
6
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
6.3
7.6
19
31
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.9
7.6
22
58
N03AE01
ATC
clonazepam; systemic
2.9
7.5
34
120
4347
FHL
Osteotomy of the upper jaw
81.1
7.4
8
*
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.3
7.4
28
89
UDC00
NOMESCO Finland
Ear microscopy
2.4
7.3
50
218
K07.09
ICD-10 Finland
Anomaly in the size of the jaws UNS
+∞
7.3
7
*
K07.6
ICD-10 Finland
Temporomandibular joint disorders
7.4
7.2
16
22
T84.62
ICD-10 Finland
Osteitis associated with dental implants
30.4
7.2
9
*
M01AE02
ATC
naproxen; oral, rectal
1.6
7.0
359
2912
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
6.8
6.9
16
24
A02BC02
ATC
pantoprazole; systemic
1.6
6.8
339
2721
H02AB06
ATC
prednisolone; systemic
1.6
6.8
241
1789
EBA40
NOMESCO Finland
Extraction of apex of root of tooth
7.9
6.6
14
18
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
12.4
6.6
11
9
RT160, ,
NOMESCO Finland
12.4
6.6
11
9
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
6.6
51
235
ECA50
NOMESCO Finland
Periodontal flap surgery
8.8
6.6
13
15
ZYC01
NOMESCO Finland
Remote contact by phone
2.3
6.6
48
216
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
7.0
6.5
15
22
ZXA00
NOMESCO Finland
Right side
1.8
6.5
109
662
R51.81
ICD-10 Finland
Facial pain NOS
3.5
6.5
22
65
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
70.6
6.4
7
*
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
18.2
6.3
9
5
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
18.2
6.3
9
5
7143D
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[OLIGARTHRITIS JUVENILIS]
+∞
6.3
6
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.2
226
1677
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
5.8
6.2
16
28
EMAK, ,
NOMESCO Finland
2.7
6.1
32
123
F45.8
ICD-10 Finland
Other somatoform disorders
2.0
6.0
62
321
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
435
3652
1.77
7.98
5.8
4.1
8.69
9.21
mm/h
0.52
422
3463
220
1611
1.59
6.49
3.2
2.7
0.00
0.03
estimate
1.92
74
502
337
2774
1.51
5.54
3.8
3.4
0.00
0.02
estimate
1.08
89
566
331
2732
1.49
5.25
3.8
3.3
0.00
0.00
estimate
0.50
92
595
332
2755
1.48
5.04
3.8
3.3
0.00
2.54
estimate
0.50
90
594
351
2949
1.48
4.98
9.6
9.0
3.65
3.98
e9/l
2.74
320
2581
260
2101
1.43
4.29
3.7
3.1
0.00
0.03
estimate
2.03
77
506
191
1470
1.45
4.06
4.0
3.3
0.00
0.01
estimate
1.34
89
581
47
256
1.91
3.98
1.6
1.7
—
—
—
0
0
405
3578
1.44
3.87
7.9
7.4
72.59
77.69
u/l
2.20
394
3419
132
965
1.48
3.61
3.0
2.5
6.28
8.53
e6/l
0.82
124
869
20
436
0.44
3.40
2.8
4.8
—
—
—
0
0
148
1128
1.42
3.22
1.9
1.9
0.90
0.95
mg/l
0.10
106
852
247
2061
1.35
3.06
5.2
7.2
1.22
1.22
mmol/l
0.63
216
1781
221
1818
1.35
2.99
4.6
5.0
37.99
37.14
g/l
1.70
202
1737
263
2242
1.32
2.72
2.6
2.6
77.06
73.20
nmol/l
1.46
246
2092
101
740
1.44
2.71
3.3
3.4
173.07
426.83
ng/l
0.78
56
439
193
1575
1.34
2.70
1.4
1.4
0.90
2.02
u/ml
1.71
55
436
328
2893
1.31
2.60
3.1
3.2
80.52
85.74
ug/l
0.33
319
2751
102
755
1.43
2.59
2.7
2.4
2.43
2.42
mmol/l
0.29
94
682
532
5067
1.62
2.58
14.9
12.2
19.22
20.52
mg/l
0.48
432
4004
34
194
1.80
2.56
1.5
1.6
0.03
0.05
iu/ml
—
10
24
179
1456
1.33
2.54
3.1
2.6
55.65
61.43
u/l
0.80
168
1370
359
3224
1.30
2.40
4.8
4.0
345.71
410.68
e6/l
—
7
40
96
721
1.40
2.25
2.2
2.5
14.98
14.73
umol/l
0.13
89
675
81
592
1.43
2.21
2.1
2.6
25.63
24.60
%
0.30
73
559
58
398
1.51
2.18
2.5
2.7
—
—
—
0
0
10
36
2.81
2.14
1.0
1.4
66.40
68.97
umol/l
—
10
36
26
146
1.82
2.10
1.1
1.1
3.67
7.86
u/ml
0.80
16
69
14
278
0.49
1.92
1.1
1.4
—
—
—
0
0
178
1497
1.27
1.90
3.0
3.1
2.35
2.36
mmol/l
0.12
169
1393
16
79
2.05
1.87
1.7
1.7
5.81
4.99
mmol/24h
0.28
16
69
148
1220
1.29
1.85
2.5
2.2
2.54
2.64
mg/l
0.25
135
1065
6
17
3.55
1.84
1.0
1.0
—
—
—
0
0
87
667
1.36
1.81
2.1
2.5
2.51
2.41
g/l
0.88
81
620
11
47
2.37
1.78
1.5
1.5
0.55
0.48
e9/l
0.37
11
47
27
164
1.68
1.71
1.1
1.1
8.29
5.32
u/ml
0.21
16
86
25
150
1.70
1.66
1.7
2.0
—
—
—
0
0
68
509
1.38
1.65
1.6
1.6
1251.90
1168.03
nmol/l
0.25
51
388
205
1778
1.24
1.65
3.7
3.2
30.56
30.04
u/l
0.08
194
1699
13
63
2.09
1.61
1.1
1.1
—
—
—
0
0
28
177
1.61
1.54
1.1
1.1
1.04
2.04
u/ml
0.77
14
92
101
816
1.29
1.48
1.5
1.6
462.52
47368846.98
pmol/l
1.57
89
722
13
67
1.96
1.39
2.0
1.5
—
—
—
0
0
138
1170
1.24
1.35
1.4
1.5
20.10
20.56
nmol/l
0.16
121
1028
137
1163
1.23
1.32
4.1
4.0
90.83
95.86
%
1.53
132
1137
21
129
1.65
1.31
1.3
1.9
—
—
—
0
0
24
153
1.59
1.31
1.3
1.1
—
—
—
0
0
59
451
1.34
1.29
1.2
1.5
22.28
22.63
iu/l
0.03
53
388
51
381
1.37
1.29
2.1
3.7
4.43
4.67
pmol/l
0.97
44
344
265
2403
1.19
1.28
5.3
6.1
10.02
11.04
umol/l
1.12
250
2291
206
1827
1.20
1.27
4.8
7.0
1.22
1.22
mmol/l
0.39
190
1698
27
179
1.53
1.26
1.4
1.2
2.32
6.15
u/ml
—
5
28
165
1436
1.21
1.25
3.7
3.0
83.54
71.72
e6/l
0.09
132
1063
13
70
1.88
1.24
1.5
1.3
—
—
—
0
0
290
2667
1.18
1.15
4.3
5.1
6.20
6.37
mmol/l
0.72
270
2450
20
305
0.64
1.14
2.1
1.7
0.33
0.27
mg/l
—
9
136
144
1248
1.20
1.13
2.5
2.2
138.94
211.88
u/l
0.76
138
1200
12
66
1.84
1.09
1.7
1.3
0.51
0.50
nmol/l
0.05
12
61
202
1812
1.18
1.07
1.8
1.9
98.63
97.49
pmol/l
0.12
97
970
23
154
1.51
1.05
1.3
1.1
—
—
—
0
0
154
1353
1.19
1.04
2.4
2.4
—
—
—
0
0
5
23
2.18
0.98
2.0
2.0
46.60
82.51
ug/l
—
5
23
141
1238
1.18
0.96
3.6
2.8
0.14
0.39
e6/l
2.09
110
876
29
208
1.42
0.96
1.1
1.1
2.52
3.31
u/ml
0.19
17
111
254
2337
1.15
0.95
2.9
2.7
—
—
estimate
—
0
0
51
402
1.29
0.94
1.0
1.0
—
—
—
0
0
7
37
1.90
0.94
1.3
1.1
—
—
—
0
0
436
4177
1.18
0.94
3.6
3.7
—
—
—
0
0
143
1261
1.18
0.93
2.2
2.2
—
—
—
0
0
6
31
1.95
0.84
1.5
1.2
187.83
180.58
pmol/l
—
6
31
434
4171
1.16
0.83
5.0
4.4
14.28
14.39
pmol/l
0.50
414
3889
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
6
33
1.83
0.79
1.2
1.1
1682.00
1703.79
miu/ml
—
6
33
0
25
0.00
0.79
0.0
2.9
—
1.36
—
0
25
491
4771
1.19
0.79
5.8
5.3
1.74
1.80
mu/l
0.62
476
4530
6
34
1.77
0.76
1.5
3.1
—
—
—
0
0
49
397
1.26
0.76
1.3
1.3
—
—
—
0
0
34
263
1.31
0.75
1.8
2.1
1.29
4.55
iu/ml
—
9
55
37
290
1.29
0.74
1.6
1.6
—
—
—
0
0
74
629
1.20
0.74
2.0
2.0
—
—
—
0
0
23
168
1.38
0.72
2.3
2.6
5.75
6.56
umol/l
0.14
15
123
17
117
1.47
0.72
1.1
1.1
—
—
—
0
0
537
5271
1.26
0.72
12.6
10.2
25.22
26.08
u/l
0.70
527
5163
20
274
0.72
0.71
1.6
1.8
2.38
3.38
mg/l
0.64
15
194
125
1116
1.15
0.70
1.4
1.3
28.09
27.52
iu/ml
0.02
32
331
77
662
1.19
0.69
4.3
4.3
1.59
2.04
ug/l
0.44
71
600
12
77
1.57
0.69
1.9
3.4
1.39
1.73
ratio
—
7
44
7
119
0.58
0.68
3.3
1.8
—
—
—
0
0
482
4691
1.16
0.68
13.7
10.9
93.11
93.05
ml/min/173m2
0.02
451
4197
5
28
1.79
0.66
1.2
1.1
—
—
—
0
0
116
1039
1.15
0.63
1.4
1.3
9.02
8.46
u/ml
0.03
52
430
14
96
1.47
0.62
1.7
1.3
—
—
—
0
0
13
187
0.69
0.62
2.2
2.4
1.02
1.02
ratio
0.38
13
176
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
61
522
1.19
0.59
3.7
3.8
24.19
22.43
%
0.38
19
217
35
283
1.25
0.58
1.1
1.1
0.86
0.89
g/l
0.49
35
283
6
35
1.72
0.58
1.2
1.4
4.22
7.57
u/l
—
6
29
470
4811
0.88
0.57
4.6
4.3
4.73
4.76
mmol/l
0.30
454
4594
44
366
1.22
0.57
5.1
12.1
0.46
0.91
mmol/l
0.31
34
309
16
116
1.39
0.55
1.9
1.7
—
—
—
0
0
19
143
1.34
0.53
1.8
1.8
—
—
—
0
0
52
444
1.19
0.53
2.6
2.4
36.91
32.81
u/l
0.22
45
374
65
739
0.86
0.50
3.3
2.6
1.13
0.94
e6/l
0.22
27
353
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
11
155
0.70
0.49
1.0
1.4
51.73
159.34
pmol/l
0.86
11
150
34
281
1.22
0.48
2.4
1.9
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
103.43
115.09
pmol/l
—
7
46
470
4796
0.89
0.46
4.4
4.2
1.47
1.48
mmol/l
0.29
454
4557
501
4921
1.13
0.45
13.2
12.9
3.90
3.92
mmol/l
0.84
492
4801
7
51
1.38
0.44
1.7
1.4
3.59
6.04
umol/l
—
7
46
132
1221
1.11
0.44
1.7
1.5
—
—
—
0
0
17
131
1.31
0.42
1.6
1.4
320.82
324.09
ug/g
0.02
11
72
22
176
1.26
0.42
1.1
1.1
10.01
6.62
u/ml
0.31
11
107
33
277
1.20
0.42
1.1
1.1
1.49
1.55
g/l
0.64
33
277
0
15
0.00
0.41
0.0
1.0
—
0.00
—
0
10
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
16
0.00
0.41
0.0
2.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
44.81
—
0
16
0
16
0.00
0.41
0.0
2.1
—
—
—
0
0
40
343
1.18
0.41
1.3
1.4
228.70
254.65
miu/ml
0.15
14
173
98
896
1.11
0.41
2.9
3.1
432.51
683.29
ng/l
0.91
79
719
10
71
1.42
0.39
1.6
1.5
—
—
—
0
0
172
1621
1.09
0.39
1.8
1.8
—
—
—
0
0
564
5599
1.28
0.37
21.3
18.5
90.26
90.03
fl
0.71
564
5559
499
4914
1.11
0.36
13.1
12.8
139.68
139.67
mmol/l
0.02
492
4811
41
357
1.16
0.36
1.7
1.4
—
—
—
0
0
476
4838
0.91
0.36
4.9
4.7
2.85
2.84
mmol/l
0.14
463
4609
5
79
0.63
0.35
1.0
1.1
90.80
95.43
%
—
5
69
212
2024
1.07
0.34
2.0
1.9
1.40
1.35
mmol/l
0.31
187
1774
383
3735
1.08
0.34
3.3
3.3
33.35
37.83
u/l
1.07
372
3605
444
4523
0.92
0.34
3.7
3.7
1.20
1.24
mmol/l
0.61
425
4274
6
45
1.34
0.34
2.3
3.6
21.00
41.31
u/ml
—
6
45
131
1229
1.09
0.33
3.7
3.1
1.02
2.31
kg/l
0.50
90
783
6
86
0.69
0.33
1.8
1.7
—
—
—
0
0
6
88
0.68
0.33
3.3
1.6
—
—
—
0
0
6
46
1.31
0.33
1.5
1.6
—
—
—
0
0
17
137
1.25
0.32
1.5
1.2
—
1.17
—
0
7
34
295
1.16
0.32
2.2
4.3
5.06
5.11
kpa
0.13
34
288
35
306
1.15
0.30
7.5
10.5
24.95
24.87
mmol/l
0.05
35
306
10
75
1.34
0.30
1.4
1.4
—
—
—
0
0
10
75
1.34
0.30
1.4
1.4
—
—
—
0
0
13
102
1.28
0.30
1.1
1.2
—
—
—
0
0
25
213
1.18
0.29
1.6
1.6
8.28
7.60
u/ml
—
6
55
21
176
1.20
0.29
1.9
2.1
2.27
4.94
iu/l
—
6
74
22
259
0.84
0.29
2.7
4.3
1.81
1.45
mmol/l
0.28
16
182
124
1169
1.08
0.29
2.1
2.2
—
—
—
0
0
31
354
0.87
0.28
1.8
2.5
77.25
75.77
ml/min/173m2
0.10
16
149
9
119
0.75
0.27
2.2
1.7
0.15
3.46
ug/l
—
9
113
9
120
0.75
0.27
2.9
1.8
—
—
—
0
0
8
65
1.23
0.27
1.0
1.1
—
—
—
0
0
17
203
0.83
0.26
1.5
3.9
0.64
0.60
%
0.13
17
203
20
169
1.19
0.26
4.3
6.0
1.19
1.29
mg/l
0.34
20
155
5
75
0.66
0.26
4.2
2.4
551.20
118.49
ug/min
—
5
47
447
4402
1.07
0.25
4.8
4.9
36.47
37.60
mmol/mol
3.41
428
4200
50
548
0.90
0.25
1.3
1.3
110.04
136.78
u/ml
0.24
24
223
27
307
0.87
0.24
1.6
2.3
25.21
39.78
u/ml
0.77
27
295
34
303
1.13
0.24
5.4
3.2
1.22
1.23
mmol/l
0.23
28
260
17
143
1.19
0.23
2.4
2.4
8.07
10.93
mg/l
1.40
17
134
29
327
0.88
0.23
3.5
4.5
3.26
20.42
ug/l
0.69
18
260
28
247
1.14
0.23
1.3
1.4
—
—
—
0
0
7
94
0.74
0.22
2.6
2.6
—
—
—
0
0
14
116
1.21
0.22
2.8
2.0
234.43
197.42
pmol/l
1.11
14
111
5
42
1.19
0.21
1.0
1.1
276.80
291.22
mg/l
—
5
37
23
201
1.15
0.21
1.3
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.08
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
1.77
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
2.24
—
0
7
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
13
155
0.84
0.20
1.4
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
30
269
1.12
0.20
1.8
1.8
—
—
—
0
0
6
51
1.18
0.19
1.0
1.3
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
6
52
1.16
0.19
3.5
1.8
—
—
—
0
0
44
406
1.09
0.18
3.5
4.2
230.18
235.14
u/l
0.11
44
391
121
1160
1.05
0.18
3.7
4.4
6.41
10.09
mg/mmol
0.50
81
729
12
100
1.20
0.18
1.2
1.9
0.00
0.00
g/l
-0.00
12
95
21
185
1.14
0.18
3.1
3.0
174.81
173.40
%
0.03
21
177
28
252
1.12
0.18
1.4
1.6
—
—
—
0
0
7
60
1.17
0.18
3.1
1.8
—
—
—
0
0
7
61
1.15
0.17
1.0
1.1
—
—
—
0
0
27
243
1.12
0.17
1.5
1.6
60.49
56.65
ug/l
0.16
27
243
7
62
1.13
0.17
1.0
1.0
—
—
—
0
0
8
72
1.11
0.16
1.1
1.3
—
—
—
0
0
33
359
0.91
0.16
2.5
4.4
4.55
4.81
kpa
0.49
33
349
42
391
1.08
0.15
2.2
2.3
35.57
17.25
au/ml
—
6
40
33
357
0.92
0.14
1.6
1.5
58.70
62.78
ug/l
0.23
28
309
21
190
1.11
0.13
1.5
1.7
0.20
0.23
g/l
0.72
21
184
60
571
1.06
0.12
2.1
3.0
6.49
6.63
umol/l
0.02
45
493
78
749
1.05
0.12
1.9
2.0
—
—
—
0
0
63
602
1.05
0.11
1.5
1.7
3.39
3.49
mmol/l
0.32
41
426
22
201
1.10
0.11
2.0
1.8
—
—
—
0
0
66
689
0.95
0.11
3.3
2.7
2.63
3.93
e6/l
1.00
27
300
11
96
1.15
0.10
2.9
2.0
123.55
134.30
g/l
1.00
11
77
54
564
0.95
0.09
4.4
6.7
1.11
1.07
mmol/l
0.49
49
527
82
793
1.04
0.09
1.6
1.8
3.39
3.45
ratio
0.15
60
605
10
87
1.15
0.09
1.2
1.1
—
—
—
0
0
20
217
0.92
0.09
1.5
1.5
—
—
—
0
0
13
116
1.12
0.09
1.3
1.1
3.93
2.04
eliau/ml
—
7
57
14
126
1.11
0.09
1.1
1.7
2.78
15.68
e6/l
—
9
91
6
57
1.05
0.08
1.0
1.1
—
—
—
0
0
5
62
0.80
0.08
1.2
1.4
—
—
—
0
0
5
63
0.79
0.08
1.2
1.4
—
—
—
0
0
5
63
0.79
0.08
1.2
1.4
—
—
—
0
0
107
1096
0.97
0.08
2.2
2.6
304.64
321.06
umol/l
1.14
101
1003
6
71
0.84
0.07
1.2
1.5
—
—
—
0
0
7
85
0.82
0.07
1.7
1.2
—
—
—
0
0
9
88
1.02
0.07
5.7
2.6
5.31
6.62
pmol/l
—
9
88
91
889
1.03
0.06
2.0
2.1
—
—
—
0
0
9
105
0.85
0.06
2.6
1.6
—
—
—
0
0
31
325
0.95
0.06
1.5
1.5
—
—
—
0
0
12
109
1.10
0.06
1.4
1.4
322.75
349.51
mu/l
0.13
12
91
29
304
0.95
0.06
1.6
1.7
—
—
—
0
0
48
496
0.96
0.05
6.1
8.7
104.94
104.82
mmol/l
0.09
48
496
51
494
1.04
0.05
2.2
2.2
2319.66
4915.19
u/l
0.63
16
203
39
405
0.96
0.05
2.9
5.0
5.94
5.79
kpa
0.69
39
392
458
4600
0.98
0.05
4.3
4.0
5.57
5.70
mmol/l
1.38
439
4316
42
407
1.03
0.04
2.5
2.8
0.78
0.69
ug/l
0.26
19
229
11
101
1.09
0.04
1.2
1.9
0.00
0.00
g/l
-0.00
11
90
32
331
0.96
0.03
1.5
1.5
0.99
0.94
ratio
0.29
16
208
32
331
0.96
0.03
1.5
1.5
1.08
1.21
ratio
0.34
17
208
32
331
0.96
0.03
1.5
1.5
1.06
1.17
ratio
0.42
16
208
45
439
1.03
0.03
2.3
2.0
—
—
—
0
0
43
421
1.02
0.02
1.4
1.5
—
—
—
0
0
10
107
0.93
0.02
1.0
1.1
—
—
—
0
0
17
177
0.96
0.01
1.1
1.2
—
—
—
0
0
63
638
0.99
0.01
1.5
1.6
1192.79
978.69
mu/l
0.26
56
554
38
387
0.98
0.01
2.8
5.2
1.33
1.70
mmol/l
0.40
33
331
11
104
1.06
0.01
1.5
1.2
—
—
—
0
0
15
146
1.03
0.00
1.3
1.2
—
—
—
0
0
15
148
1.01
0.00
2.3
1.5
—
—
—
0
0
145
1453
1.00
0.00
3.0
3.5
8.83
8.31
mmol/l
0.48
132
1274
45
449
1.00
0.00
2.3
2.0
—
—
—
0
0
149
1489
1.00
0.00
3.0
2.9
12.83
78.69
ng/l
0.72
66
802
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
3.1
1.9
—
—
—
0
0
8
89
0.90
-0.00
4.1
3.4
14.52
27.29
mg/l
—
8
62
0
5
0.00
-0.00
0.0
1.0
—
8.83
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
8.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
8.28
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
13.44
—
0
7
6
65
0.92
-0.00
3.0
4.4
7.58
411.59
u/ml
—
6
60
0
5
0.00
-0.00
0.0
3.0
—
0.80
—
0
5
6
68
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_ASYMMETRY_JAW and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ASYMMETRY_JAW | 0.842 [0.65, 1.1] | 0.204 |
| Birth year | 0.99 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 2066 males with K11_ASYMMETRY_JAW died.
Mortality risk
Mortality risk for people of age
years, who have K11_ASYMMETRY_JAW.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.188% |
| 5 | No data | 1.004% |
| 10 | No data | 2.642% |
| 15 | No data | 5.127% |
| 20 | No data | 8.709% |
Relationships between endpoints
↥Index endpoint: K11_ASYMMETRY_JAW – Asymmetry of jaw
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data